LOCUS       DBEJZJ010000001       121544 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000001 DBEJZJ010000000
VERSION     DBEJZJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 121544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 121544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..121544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.01"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..632)
                     /locus_tag="ACL3R8_000001"
                     /pseudo
     CDS             complement(1..632)
                     /locus_tag="ACL3R8_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            928..1233
                     /locus_tag="ACL3R8_000002"
                     /pseudo
     CDS             928..1233
                     /locus_tag="ACL3R8_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            1365..2309
                     /gene="manA"
                     /locus_tag="ACL3R8_000003"
     CDS             1365..2309
                     /gene="manA"
                     /locus_tag="ACL3R8_000003"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR1312971.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(2330..3808)
                     /locus_tag="ACL3R8_000004"
     CDS             complement(2330..3808)
                     /locus_tag="ACL3R8_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR1312972.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFEKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            3913..4662
                     /locus_tag="ACL3R8_000005"
     CDS             3913..4662
                     /locus_tag="ACL3R8_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGR1312973.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLYTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(4682..5137)
                     /locus_tag="ACL3R8_000006"
     CDS             complement(4682..5137)
                     /locus_tag="ACL3R8_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR1312974.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5157..6331)
                     /locus_tag="ACL3R8_000007"
                     /pseudo
     CDS             complement(5157..6331)
                     /locus_tag="ACL3R8_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
     gene            complement(6390..7235)
                     /locus_tag="ACL3R8_000008"
     CDS             complement(6390..7235)
                     /locus_tag="ACL3R8_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1312975.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSIQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            7360..7917
                     /locus_tag="ACL3R8_000009"
     CDS             7360..7917
                     /locus_tag="ACL3R8_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR1312976.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7936..8403
                     /locus_tag="ACL3R8_000010"
     CDS             7936..8403
                     /locus_tag="ACL3R8_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR1312977.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            8492..9121
                     /gene="upp"
                     /locus_tag="ACL3R8_000011"
     CDS             8492..9121
                     /gene="upp"
                     /locus_tag="ACL3R8_000011"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR1312978.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            9295..9885
                     /gene="clpP"
                     /locus_tag="ACL3R8_000012"
     CDS             9295..9885
                     /gene="clpP"
                     /locus_tag="ACL3R8_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR1312979.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9964..10212
                     /locus_tag="ACL3R8_000013"
     CDS             9964..10212
                     /locus_tag="ACL3R8_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR1312980.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            10314..11474
                     /locus_tag="ACL3R8_000014"
     CDS             10314..11474
                     /locus_tag="ACL3R8_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1312981.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINGAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11742..12611
                     /locus_tag="ACL3R8_000015"
     CDS             11742..12611
                     /locus_tag="ACL3R8_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR1312982.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            12615..13571
                     /locus_tag="ACL3R8_000016"
     CDS             12615..13571
                     /locus_tag="ACL3R8_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR1312983.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            13571..14335
                     /locus_tag="ACL3R8_000017"
     CDS             13571..14335
                     /locus_tag="ACL3R8_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312984.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            14335..15045
                     /locus_tag="ACL3R8_000018"
     CDS             14335..15045
                     /locus_tag="ACL3R8_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1312985.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            15353..16009
                     /locus_tag="ACL3R8_000019"
     CDS             15353..16009
                     /locus_tag="ACL3R8_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR1312986.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            16116..17211
                     /gene="prfB"
                     /locus_tag="ACL3R8_000020"
     CDS             join(16116..16187,16189..17211)
                     /gene="prfB"
                     /locus_tag="ACL3R8_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR1312987.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            17229..17921
                     /gene="ftsE"
                     /locus_tag="ACL3R8_000021"
     CDS             17229..17921
                     /gene="ftsE"
                     /locus_tag="ACL3R8_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR1312988.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17914..18840
                     /gene="ftsX"
                     /locus_tag="ACL3R8_000022"
     CDS             17914..18840
                     /gene="ftsX"
                     /locus_tag="ACL3R8_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR1312989.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSAVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            19108..21288
                     /locus_tag="ACL3R8_000023"
     CDS             19108..21288
                     /locus_tag="ACL3R8_000023"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR1312990.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            21340..22155
                     /locus_tag="ACL3R8_000024"
     CDS             21340..22155
                     /locus_tag="ACL3R8_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR1312991.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            22295..23638
                     /locus_tag="ACL3R8_000025"
     CDS             22295..23638
                     /locus_tag="ACL3R8_000025"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1312992.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLEIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23853..25043
                     /gene="metK"
                     /locus_tag="ACL3R8_000026"
     CDS             23853..25043
                     /gene="metK"
                     /locus_tag="ACL3R8_000026"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR1312993.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            25478..26413
                     /locus_tag="ACL3R8_000027"
     CDS             25478..26413
                     /locus_tag="ACL3R8_000027"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR1312994.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIKELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            26447..27484
                     /gene="holA"
                     /locus_tag="ACL3R8_000028"
     CDS             26447..27484
                     /gene="holA"
                     /locus_tag="ACL3R8_000028"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR1312995.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKVDSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27657..28262
                     /gene="sodA"
                     /locus_tag="ACL3R8_000029"
     CDS             27657..28262
                     /gene="sodA"
                     /locus_tag="ACL3R8_000029"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR1312996.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            28419..28949
                     /locus_tag="ACL3R8_000030"
     CDS             28419..28949
                     /locus_tag="ACL3R8_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR1312997.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISCLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SHKEDKGQRHFVIRQK"
     gene            28970..30055
                     /gene="rlmN"
                     /locus_tag="ACL3R8_000031"
     CDS             28970..30055
                     /gene="rlmN"
                     /locus_tag="ACL3R8_000031"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR1312998.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVDCNIGCTFCASDLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEYGT
                     DIDAACGQLRSNTMKRDRQKAVAEVNP"
     gene            30057..30530
                     /locus_tag="ACL3R8_000032"
     CDS             30057..30530
                     /locus_tag="ACL3R8_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR1312999.1"
                     /translation="MTKKRELILRLGVAVYSLCIVYFCFTPQATVEVGTPGIQHLGRL
                     VFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKKVLL
                     FSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN"
     gene            30532..32073
                     /locus_tag="ACL3R8_000033"
     CDS             30532..32073
                     /locus_tag="ACL3R8_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1313000.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMTEDGADVDALMEEVGELQDRLESRDFYILDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKSLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(32129..32932)
                     /locus_tag="ACL3R8_000034"
     CDS             complement(32129..32932)
                     /locus_tag="ACL3R8_000034"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR1313001.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNHALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(33015..33227)
                     /locus_tag="ACL3R8_000035"
     CDS             complement(33015..33227)
                     /locus_tag="ACL3R8_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313002.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(33707..33916)
                     /locus_tag="ACL3R8_000036"
     CDS             complement(33707..33916)
                     /locus_tag="ACL3R8_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313003.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            34086..34358
                     /gene="rpsP"
                     /locus_tag="ACL3R8_000037"
     CDS             34086..34358
                     /gene="rpsP"
                     /locus_tag="ACL3R8_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR1313004.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            34378..34617
                     /gene="kphA"
                     /locus_tag="ACL3R8_000038"
     CDS             34378..34617
                     /gene="kphA"
                     /locus_tag="ACL3R8_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR1313005.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34766..35090
                     /locus_tag="ACL3R8_000039"
                     /pseudo
     CDS             34766..35090
                     /locus_tag="ACL3R8_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            35194..35982
                     /locus_tag="ACL3R8_000040"
     CDS             35194..35982
                     /locus_tag="ACL3R8_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1313006.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            36013..36531
                     /gene="rimM"
                     /locus_tag="ACL3R8_000041"
     CDS             36013..36531
                     /gene="rimM"
                     /locus_tag="ACL3R8_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR1313007.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            36521..37240
                     /gene="trmD"
                     /locus_tag="ACL3R8_000042"
     CDS             36521..37240
                     /gene="trmD"
                     /locus_tag="ACL3R8_000042"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR1313008.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            37252..37590
                     /locus_tag="ACL3R8_000043"
     CDS             37252..37590
                     /locus_tag="ACL3R8_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR1313009.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(37620..37940)
                     /locus_tag="ACL3R8_000044"
     CDS             complement(37620..37940)
                     /locus_tag="ACL3R8_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313010.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            38038..38253
                     /locus_tag="ACL3R8_000045"
     CDS             38038..38253
                     /locus_tag="ACL3R8_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR1313011.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(38250..38438)
                     /locus_tag="ACL3R8_000046"
     CDS             complement(38250..38438)
                     /locus_tag="ACL3R8_000046"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313012.1"
                     /translation="MTQYPFFYFENLYSMKIKEQTRKLAAGCSKHCFEVVDETDEVSN
                     HTYGKAKLMRFEEIFEEY"
     gene            complement(38458..38994)
                     /locus_tag="ACL3R8_000047"
     CDS             complement(38458..38994)
                     /locus_tag="ACL3R8_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR1313013.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            complement(39190..40536)
                     /gene="gor"
                     /locus_tag="ACL3R8_000048"
     CDS             complement(39190..40536)
                     /gene="gor"
                     /locus_tag="ACL3R8_000048"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR1313014.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            40822..42021
                     /locus_tag="ACL3R8_000049"
     CDS             40822..42021
                     /locus_tag="ACL3R8_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR1313015.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            42005..42706
                     /locus_tag="ACL3R8_000050"
     CDS             42005..42706
                     /locus_tag="ACL3R8_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313016.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            42708..43967
                     /locus_tag="ACL3R8_000051"
     CDS             42708..43967
                     /locus_tag="ACL3R8_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313017.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            44091..46088
                     /gene="metG"
                     /locus_tag="ACL3R8_000052"
     CDS             44091..46088
                     /gene="metG"
                     /locus_tag="ACL3R8_000052"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR1313018.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            46138..46329
                     /locus_tag="ACL3R8_000053"
     CDS             46138..46329
                     /locus_tag="ACL3R8_000053"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313019.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHIYGKATLTKFELDFRRV"
     gene            46417..53118
                     /gene="bgaA"
                     /locus_tag="ACL3R8_000054"
     CDS             46417..53118
                     /gene="bgaA"
                     /locus_tag="ACL3R8_000054"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR1313020.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEALKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIINTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRAIIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGATGQITLTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(53428..53805)
                     /locus_tag="ACL3R8_000055"
     CDS             complement(53428..53805)
                     /locus_tag="ACL3R8_000055"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1313021.1"
                     /translation="MFDKKQKRGYKESAKNLANWHYNDKEDSYTHPDGWYYRFHHTKH
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKI
                     DVEPVFGQIKASLGYKRCNLRGK"
     gene            complement(53970..54215)
                     /locus_tag="ACL3R8_000056"
     CDS             complement(53970..54215)
                     /locus_tag="ACL3R8_000056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313022.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEDCHFHAF
                     YHAFDRLSYHLKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(54427..54786)
                     /locus_tag="ACL3R8_000057"
     CDS             complement(54427..54786)
                     /locus_tag="ACL3R8_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR1313023.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            54878..55834
                     /locus_tag="ACL3R8_000058"
                     /pseudo
     CDS             54878..55834
                     /locus_tag="ACL3R8_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            55818..56375
                     /locus_tag="ACL3R8_000059"
     CDS             55818..56375
                     /locus_tag="ACL3R8_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1313024.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            56368..56622
                     /locus_tag="ACL3R8_000060"
     CDS             56368..56622
                     /locus_tag="ACL3R8_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313025.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            56634..58688
                     /locus_tag="ACL3R8_000061"
     CDS             56634..58688
                     /locus_tag="ACL3R8_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR1313026.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLIWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLPSRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            58872..59732
                     /locus_tag="ACL3R8_000062"
     CDS             58872..59732
                     /locus_tag="ACL3R8_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR1313027.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            59943..60653
                     /gene="ccdA2"
                     /locus_tag="ACL3R8_000063"
     CDS             59943..60653
                     /gene="ccdA2"
                     /locus_tag="ACL3R8_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR1313028.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            60673..61239
                     /locus_tag="ACL3R8_000064"
     CDS             60673..61239
                     /locus_tag="ACL3R8_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR1313029.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            61250..62362
                     /gene="msrB"
                     /locus_tag="ACL3R8_000065"
     CDS             61250..62362
                     /gene="msrB"
                     /locus_tag="ACL3R8_000065"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR1313030.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            62630..63367
                     /locus_tag="ACL3R8_000066"
     CDS             62630..63367
                     /locus_tag="ACL3R8_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1313031.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            63364..65055
                     /locus_tag="ACL3R8_000067"
     CDS             63364..65055
                     /locus_tag="ACL3R8_000067"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1313032.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSAGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            65171..65734
                     /locus_tag="ACL3R8_000068"
     CDS             65171..65734
                     /locus_tag="ACL3R8_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR1313033.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            65756..71419
                     /locus_tag="ACL3R8_000069"
     CDS             65756..71419
                     /locus_tag="ACL3R8_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR1313034.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTVKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEET
                     VLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETR
                     EEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIE
                     KPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNT
                     GTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKV
                     EIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVT
                     EEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNP
                     NGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIK
                     NINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMT
                     NVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFN
                     PRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSN
                     DMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEV
                     TEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDS
                     PLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVA
                     ELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLE
                     ESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYG
                     VKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLS
                     GNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNG
                     QHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRETFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFF
                     GRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAY
                     LGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKL
                     QTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSG
                     PHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDF
                     IIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTK
                     DLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            71488..73209
                     /gene="pabB"
                     /locus_tag="ACL3R8_000070"
     CDS             71488..73209
                     /gene="pabB"
                     /locus_tag="ACL3R8_000070"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR1313035.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            73210..73827
                     /locus_tag="ACL3R8_000071"
     CDS             73210..73827
                     /locus_tag="ACL3R8_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1313036.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSRCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            73877..74875
                     /locus_tag="ACL3R8_000072"
     CDS             73877..74875
                     /locus_tag="ACL3R8_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR1313037.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            75002..75961
                     /locus_tag="ACL3R8_000073"
     CDS             75002..75961
                     /locus_tag="ACL3R8_000073"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR1313038.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            76058..76897
                     /locus_tag="ACL3R8_000074"
     CDS             76058..76897
                     /locus_tag="ACL3R8_000074"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR1313039.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(76945..77115)
                     /locus_tag="ACL3R8_000075"
     CDS             complement(76945..77115)
                     /locus_tag="ACL3R8_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR1313040.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            77236..78120
                     /gene="miaA"
                     /locus_tag="ACL3R8_000076"
     CDS             77236..78120
                     /gene="miaA"
                     /locus_tag="ACL3R8_000076"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR1313041.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            78113..79351
                     /gene="hflX"
                     /locus_tag="ACL3R8_000077"
     CDS             78113..79351
                     /gene="hflX"
                     /locus_tag="ACL3R8_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR1313042.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            79344..79967
                     /locus_tag="ACL3R8_000078"
     CDS             79344..79967
                     /locus_tag="ACL3R8_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR1313043.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLKEAAAFSGKRYFRSENRTAMLYID"
     gene            79982..80911
                     /gene="rnz"
                     /locus_tag="ACL3R8_000079"
     CDS             79982..80911
                     /gene="rnz"
                     /locus_tag="ACL3R8_000079"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR1313044.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKDDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            80932..81687
                     /locus_tag="ACL3R8_000080"
     CDS             80932..81687
                     /locus_tag="ACL3R8_000080"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1313045.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(81741..82649)
                     /locus_tag="ACL3R8_000081"
     CDS             complement(81741..82649)
                     /locus_tag="ACL3R8_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR1313046.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            82713..82982
                     /locus_tag="ACL3R8_000082"
     CDS             82713..82982
                     /locus_tag="ACL3R8_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR1313047.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            82982..83362
                     /locus_tag="ACL3R8_000083"
     CDS             82982..83362
                     /locus_tag="ACL3R8_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR1313048.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            83451..83678
                     /locus_tag="ACL3R8_000084"
     CDS             83451..83678
                     /locus_tag="ACL3R8_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313049.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(83718..84443)
                     /locus_tag="ACL3R8_000085"
     CDS             complement(83718..84443)
                     /locus_tag="ACL3R8_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR1313050.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            84605..86446
                     /gene="typA"
                     /locus_tag="ACL3R8_000086"
     CDS             84605..86446
                     /gene="typA"
                     /locus_tag="ACL3R8_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR1313051.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDSTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            86466..86720
                     /locus_tag="ACL3R8_000087"
     CDS             86466..86720
                     /locus_tag="ACL3R8_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR1313052.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            87084..87386
                     /locus_tag="ACL3R8_000088"
     CDS             87084..87386
                     /locus_tag="ACL3R8_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR1313053.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAVAGKTSEAWIWTKFGEQVSFFYDYDD"
     gene            87457..89478
                     /locus_tag="ACL3R8_000089"
                     /pseudo
     CDS             87457..89478
                     /locus_tag="ACL3R8_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            89480..90121
                     /locus_tag="ACL3R8_000090"
     CDS             89480..90121
                     /locus_tag="ACL3R8_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313054.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            90225..91577
                     /gene="murD"
                     /locus_tag="ACL3R8_000091"
     CDS             90225..91577
                     /gene="murD"
                     /locus_tag="ACL3R8_000091"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR1313055.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGEHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            91581..92639
                     /locus_tag="ACL3R8_000092"
     CDS             91581..92639
                     /locus_tag="ACL3R8_000092"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR1313056.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            92649..93878
                     /gene="divIB"
                     /locus_tag="ACL3R8_000093"
     CDS             92649..93878
                     /gene="divIB"
                     /locus_tag="ACL3R8_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR1313057.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEIEE
                     SESKEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYAT
                     MKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQF
                     PTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIK
                     AFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSK
                     IKPQLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKK
                     QEEESNRNQTTQRSSRR"
     gene            94111..94812
                     /gene="pyrF"
                     /locus_tag="ACL3R8_000094"
     CDS             94111..94812
                     /gene="pyrF"
                     /locus_tag="ACL3R8_000094"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR1313058.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            94846..95478
                     /gene="pyrE"
                     /locus_tag="ACL3R8_000095"
     CDS             94846..95478
                     /gene="pyrE"
                     /locus_tag="ACL3R8_000095"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR1313059.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            95939..96061
                     /locus_tag="ACL3R8_000096"
     CDS             95939..96061
                     /locus_tag="ACL3R8_000096"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313060.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            96157..96921
                     /locus_tag="ACL3R8_000097"
     CDS             96157..96921
                     /locus_tag="ACL3R8_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313061.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFLAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            96921..97673
                     /locus_tag="ACL3R8_000098"
     CDS             96921..97673
                     /locus_tag="ACL3R8_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313062.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            97683..98381
                     /locus_tag="ACL3R8_000099"
     CDS             97683..98381
                     /locus_tag="ACL3R8_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313063.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            98378..99025
                     /locus_tag="ACL3R8_000100"
     CDS             98378..99025
                     /locus_tag="ACL3R8_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313064.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(99112..99978)
                     /locus_tag="ACL3R8_000101"
     CDS             complement(99112..99978)
                     /locus_tag="ACL3R8_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313065.1"
                     /translation="MKLFKPLLTVLVLAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKLFGYVDNDGSYQGYDIELGNQLAQNLGVKVKYISVDAANRA
                     EYLISNKVDIILANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDTAK
                     ADDLVVEGGKVD"
     gene            complement(99990..100747)
                     /locus_tag="ACL3R8_000102"
                     /pseudo
     CDS             complement(99990..100747)
                     /locus_tag="ACL3R8_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(100748..101425)
                     /locus_tag="ACL3R8_000103"
     CDS             complement(100748..101425)
                     /locus_tag="ACL3R8_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1313066.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFRTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(101385..102065)
                     /locus_tag="ACL3R8_000104"
     CDS             complement(101385..102065)
                     /locus_tag="ACL3R8_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1313067.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            102280..102414
                     /locus_tag="ACL3R8_000105"
                     /pseudo
     CDS             102280..102414
                     /locus_tag="ACL3R8_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            102554..104044
                     /gene="lysS"
                     /locus_tag="ACL3R8_000106"
     CDS             102554..104044
                     /gene="lysS"
                     /locus_tag="ACL3R8_000106"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR1313068.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALCEQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKVIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            104668..105804
                     /gene="lctO"
                     /locus_tag="ACL3R8_000107"
     CDS             104668..105804
                     /gene="lctO"
                     /locus_tag="ACL3R8_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR1313069.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      106056..106144
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            106359..107027
                     /locus_tag="ACL3R8_000108"
     CDS             106359..107027
                     /locus_tag="ACL3R8_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR1313070.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(107024..107251)
                     /locus_tag="ACL3R8_000109"
     CDS             complement(107024..107251)
                     /locus_tag="ACL3R8_000109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313071.1"
                     /translation="MKIKEQTRKLTADCSKHCFEPVDKTDEVSSKHCFEVVDRTDEVS
                     NHTYGKVKLTWFEEIFEEYYLIKFVNIMSLL"
     gene            107354..108136
                     /gene="thiM"
                     /locus_tag="ACL3R8_000110"
     CDS             107354..108136
                     /gene="thiM"
                     /locus_tag="ACL3R8_000110"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR1313072.1"
                     /translation="MTSLKLLKKKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGMDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            108138..108767
                     /gene="thiE"
                     /locus_tag="ACL3R8_000111"
     CDS             108138..108767
                     /gene="thiE"
                     /locus_tag="ACL3R8_000111"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR1313073.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      108976..109064
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            109326..109886
                     /locus_tag="ACL3R8_000112"
     CDS             109326..109886
                     /locus_tag="ACL3R8_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1313074.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNMLSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIRLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            109887..111272
                     /locus_tag="ACL3R8_000113"
     CDS             109887..111272
                     /locus_tag="ACL3R8_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313075.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEKRNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            111274..111924
                     /locus_tag="ACL3R8_000114"
     CDS             111274..111924
                     /locus_tag="ACL3R8_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR1313076.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            111935..112627
                     /gene="tenA"
                     /locus_tag="ACL3R8_000115"
     CDS             111935..112627
                     /gene="tenA"
                     /locus_tag="ACL3R8_000115"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR1313077.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            112632..113156
                     /gene="thiW"
                     /locus_tag="ACL3R8_000116"
     CDS             112632..113156
                     /gene="thiW"
                     /locus_tag="ACL3R8_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR1313078.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            113156..113959
                     /locus_tag="ACL3R8_000117"
     CDS             113156..113959
                     /locus_tag="ACL3R8_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR1313079.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            113952..114584
                     /gene="thiE"
                     /locus_tag="ACL3R8_000118"
     CDS             113952..114584
                     /gene="thiE"
                     /locus_tag="ACL3R8_000118"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR1313080.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(114794..115585)
                     /gene="thiD"
                     /locus_tag="ACL3R8_000119"
     CDS             complement(114794..115585)
                     /gene="thiD"
                     /locus_tag="ACL3R8_000119"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR1313081.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(115669..115767)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            115951..116346
                     /locus_tag="ACL3R8_000120"
     CDS             115951..116346
                     /locus_tag="ACL3R8_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR1313082.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            116357..116728
                     /locus_tag="ACL3R8_000121"
     CDS             116357..116728
                     /locus_tag="ACL3R8_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR1313083.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            116738..118981
                     /locus_tag="ACL3R8_000122"
     CDS             116738..118981
                     /locus_tag="ACL3R8_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR1313084.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTTIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            119188..120963
                     /gene="spxB"
                     /locus_tag="ACL3R8_000123"
     CDS             119188..120963
                     /gene="spxB"
                     /locus_tag="ACL3R8_000123"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR1313085.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            121074..121421
                     /locus_tag="ACL3R8_000124"
     CDS             121074..121421
                     /locus_tag="ACL3R8_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1313086.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT        36956 a        22349 c        26698 g        35541 t
ORIGIN      
        1 ctgtatgggc atcaacagct ccataacaat agtgaaattc tcgtatatag tgactatgga
       61 catgtggacc tactcctatt ggagcccaac aagatcccag tttactgatt ctaccgaaac
      121 cagcctcatc ttggtacatc aagcgaacct tacgaaaacg tctactgctt ttaaagcgct
      181 ttcttttctt cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct
      241 ttcctaggat gttctggacg tggcataata tttcgccaac catggtgctt caacagttga
      301 tagaaggcat cacgtgtgta ggaacgacct aactcctttt tataagcctg aaataaggca
      361 tcaattgtaa caaattctcc tgcctctgta gccttcaaat ggcgggcaag aaagactttc
      421 ttttcctcaa tcgtcatata tgcatggtta cggccaccac gtgtttcttg aaggagagag
      481 tcgagttcga actcctcata tttttttaca tttcgccaaa tcgttgtttg attacagtct
      541 atagtgtatt gaatctataa cagtacacct tagctgctaa aatatttcta taaattagtt
      601 tgactttcct gatagagttg ttcacatctt atttcaaact actataaaag ttctataatc
      661 tctttataag atttgcccat cagacgaaat ataataaatt gaaactagaa tagtacacct
      721 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg ccctgttctt
      781 gtttcgtttt actatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct
      841 ttaaaaagtg ttttgatggt ttggatttct tctttagttg atttcatatc actattatat
      901 aatgcttttt gattttagta tagtattatc gtagaaaatg gactcggtgc tatggataca
      961 ccggatgaga atggttatgt agcagatgac tatcggatta cttacttaga ggcccacatc
     1021 aaggccatgc gagatgccat ttacaaagac ggggttgact tgcttggtta tacgacatgg
     1081 ggctgtatcg attcggtttc agctggcaca ggggaaatga ataagcgcta tggctttatc
     1141 tatgtagatc gagataatgt aggaaatggg actctcaaac gtagcaagaa gaagtccttc
     1201 tattggtaca tgtcatttat agcaatggtg taagcatcga gtagagcaca tttgtttact
     1261 atttttataa aatcttctcc ctgctttata agatgtaaaa aagagttcaa ttcgaactct
     1321 ttttttgcta taatgagggg agaaaaatca gacaggagat cgacatgtca gaaccattat
     1381 ttttacaatc agttatgcaa gaaaaaatct ggggtggagc caagctacgt gatgagtttg
     1441 gctacgacat cccaagtgaa aaaatcggag aatattgggc catctcagcc catccaaatg
     1501 gagtctctaa agttgccaat ggtcgttacg agggaacaga tcttgctact ttgtatgcgg
     1561 aacaccgtga attatttggc aatcgtccag aacctgtatt tccacttttg accaagatcc
     1621 tcgatgccaa cgactggctc agtgtccaag ttcacccaga cgatgcttat ggactcgagc
     1681 atgaaggcga actcggaaaa acagaatgct ggtacattat cgcagcggat gaaggttcag
     1741 agattatcta cggtcacaat gccaagtcaa aagaagaact ccgccagcaa atcgaggaca
     1801 agaactggga tgacttgttg accaaagtcc ctgttaaggc tggagatttc ttctatgtac
     1861 caagcgggac tatgcacgct atcggggcgg gtatcttcat ccttgaaacc cagcagtcta
     1921 gcgataccac ctatcgcgtc tatgactttg accgcaagga tgacaaaggc aacttgcgtg
     1981 aacttcatct tgaaaaatcc atcgatgtct tgaacattgg tgagccagca aatagccgtc
     2041 ctgtaactgt taaagcagat gatttgcgtt ccactctcct tgtatctaat gatttcttcg
     2101 cagtttacaa gtgggaaatt actggaaaag ttgactttga aaagacagct gactacagct
     2161 tattgagtgt cttagctggt caaggtcagc taactgttga cgggaaaaat tatccaattc
     2221 aaaaaggcag ccactttatc ctaccaagtg atgttgaagc ttggactctg gaagggcaag
     2281 gtttggaatt gattgttagc catccataaa aagaaagggc ctgagttcac tactcaagtc
     2341 ctttttgatt acataaattg ggcaatgaag accacaatga tgatgattgg aatgacggaa
     2401 cgaagaaacg aagaaggaag agccagactt ggaacagtcc ttgtttccat gctctttcat
     2461 cgagatggag ttcctccatt gcaagagcct ttttaaagat atagcctgta aaaagtgaaa
     2521 ggtagagagc tccaaatggc atgaggagat tggaaaccaa gaagtccata gcgtcaaaga
     2581 aggtcttacc aaaaatgtga acatccgcca tgacaccgta agatagggct gaaggaatgc
     2641 caaagacaaa ggtcaaaatt cctaaaataa cactccattt ggcacgtttg ctgttatcct
     2701 ggttggtgat attgcccaca ttgatctcca gcatcacgac agaagaagtg acagtcgcaa
     2761 agaggaagag gacgtagaaa atggttccaa aaggcatctt gtcaaagagt tgaggcaaga
     2821 cgataaagag caggctgggt cccccttcag actggatatt gaagggggat cgagcttgga
     2881 aaatggctag acctgccatg atggatatcg agatattcat ggctacgatg gagattcctg
     2941 actggactag attggttttc ttgtccaagt aagaagcata ggtcaacatg actgtaaccc
     3001 ctagtgagag ggcaaagaaa gattgtccca gagcatagag gagaccagcg ctagtcagtt
     3061 ttgaaaagtc tggtttgagg aagtaaagaa ccccttccat ggcatttggc aaactgagag
     3121 agcgaccgat gataacaaca aagatgataa agagcagggg catcatgact ttcgaagctc
     3181 tttcaatccc tttttgaacc ccacgtgata caatgaagat attcaatagg ataaaggccg
     3241 cttgagctcc tagggcaatg gctggatttg aaatgattga agtaaataac tgagcataat
     3301 cacccgttcc accaagttgg aacaatttcc caaactcaat acctagatag actagaatcc
     3361 atcctccgat aacactgtaa aaagataaga ggataaagag ggcaaaggcg ccaatccaac
     3421 cgataaagtt gtacttgtta ttcttgccca gtttttcaaa ggttttgata gcggaaacgc
     3481 cagcactacg gccaagggca aactcagcca gcaggagagg gaaaccgatt aaaatagtgg
     3541 aaatgagaaa gattagtaaa aagcctccac cgccattagc agcagtcatg tagggaaact
     3601 tccaaacgga accaagcccg atggccgagc cagcagatgc tagaataaaa ccaagtttcg
     3661 acccccattg tgatttttct gacatagtta aactctgatc tcctttttca aaataagaaa
     3721 aagctacttg agttgtcaaa tagccttctg tttgattgat agacttgact atcctatcat
     3781 gttttctaag gtctgtcaag aaaatcattt tcaagttttc atacctttct caaaaaagtt
     3841 aaaaaatttt ctcaaaaacg cttgactctg acctaagggg aggggttata ctatcattgt
     3901 aaggaggaaa tcatgtacca tataaaagaa gctgcgcagc tttcaggtgt ctctgtcaag
     3961 accctgcatc actatgacaa gataggactc ttggtcccct taaagtcgga aaacggctat
     4021 cgaacctaca gtcaagagga tttggaacgc cttcaggtca ttctttacta caaatatcta
     4081 ggcttttctt tagagaaaat agcagagctg ttaaaggaag aaaggacaga tttattgccc
     4141 catttgacta ggcagttgga ctatctaact cgcgaaaggc aacatctgta taccttgatt
     4201 tccaccttgc aaaaaactat tcaagaacaa aaaggagaaa gaaaaatgac cattgaggaa
     4261 aaattcacgg gatttagcta tcaagacaat caaaaatacc accaagaagc ggtagagaaa
     4321 tatggtcaag aagtcatggg acaagcgctc gaacgccaaa aaggtcacga agacgaggct
     4381 acggccgcct ttaaccaagt ctttcaaact ttggcacaaa atcttcaagt tggtttacct
     4441 gcaacagcaa ccgaaaacca agagcaagca gccaagctct tgcaagccat tcgcacttat
     4501 ggatttgact gctctattga ggtattcggt catatcggta aaggttacgt ctacaaccca
     4561 gagtttaagg aaaacattga caagtttggt tctggaacag cccagtacac gtcagatgcc
     4621 attgcagctt acgttcagac aaatgcagaa aaaataggct aggaatttcc tagcctattt
     4681 tttacttcaa atcataaagc cagtcgtcac cgtttttgta gtaaaagaat tcactgagat
     4741 cttcttctag aaacacacga agcatatcag acatatcatc ggttgcaagt tttagatgag
     4801 aaagattttc aaagtcctcc caccaaactt tcccttcgtc tgaagactgg agttcaccag
     4861 taaagtgttc tgtcttgtaa aaaaggacga cataacgata atccttgtcg tcataccagt
     4921 ttttgatacc acagagttgg ggtttggaaa tgatcagacc agtttcttct ttcacttcac
     4981 gaatgacagc atcgacaaag gattcgccac gttcaacatg accaccagga aaagtaatgc
     5041 caggccagtc gggactaact cggtcttgga ccaggacctt atctccgttt ttaatcatac
     5101 acatgttaac aaattcgact gcctctcttc tgttcattct tcacaacctt taatctttaa
     5161 tcataatgca gacttcccgc cacccagccg gtacagaggg cagaagtgat gttaaagcca
     5221 cccgtgtggg cattgatatc cataacttcg cctgcaaagt ggaggccagg taccagctta
     5281 ctttcaaggg ttttaggatt gatttccttg agactgactc cacccttggt aacaaaggac
     5341 tttgcaaggg acatttttcc agttacagga attttaagtt ctttaatgga ctggacaagc
     5401 tgttctcgtt ccttttcagt cagctgtttg actttttcag gatatccttg tacaaaaaat
     5461 tcggccaagc gttctggtaa caaggttttt aaagcgtttt tcaaggattt ttcccgattt
     5521 tttctagaaa tgtaaccaag ttcttctcag aaagttgagg caaaacatcg agtgagagaa
     5581 cctccccacc gtttacaaag ctagacatgc gtagggcagc aggacctgac aaaccaaagt
     5641 gggtaaagag taaatcatga gtgatgacat gcttaccata acttagggtc acatcgtcca
     5701 gagaaatccc ttgtaaggct ttatgtggaa aatctgttaa taaaggactt tcagcagcct
     5761 caagatctgt gatggtatgc ttaaaatggc gagcaatctc gtgaccaaaa ccagtcgaac
     5821 cagtcgaagg ataagactta ccacctgttg tgacaatgag tttctcacaa gtgaaggttt
     5881 gatccgctga cttaaggaca aactggtcat ctactttttt aacagaaacg atttctattt
     5941 gagtagcaac ttgaccacct agttcggtga ttttcttttc caaagcttcg ataatagtcc
     6001 gagacttgtc actggctgga aagacgcgtc cgtggtcttc gaccttaagt ttaacaccat
     6061 tttctgtaaa aaagttgatg atgtcatgat tatcgaactg ggagaaaaca ctgtaaagaa
     6121 agcgtccgtt tccaggaatt ccagctagca ggttgtctaa gctaccattg ttggtcacat
     6181 tgcaacgtcc cccaccagtc ccagctaatt tttttccaag tttccgattt ttttcgatga
     6241 ggagggtttt ctgtccataa aagctactgg aaatcgtagc catcatacca gcaggtcccc
     6301 caccgatgac aatagtatca aaatgtttca tagctctatt gtaccacaaa aaaacaagag
     6361 atgatggtca cctcttgtca agaatgcaat taatcaattt catagcccat cagcaaaccg
     6421 ccatcttctg catagaaact gcagagacca gaggttggta gaattttaat atccgcttgt
     6481 gggaaggttt cacggattcg ctctgagagc tgttgacaac atttttcgtt attgcgttgg
     6541 gccatgacaa tacggccacc agcatatcca gcttttacta actcatcata ggcagcttga
     6601 attgatttct ttgatcccct tgctttttgt agcaattcga gagttccagt ttcactagct
     6661 tttccgacca tacgaatgtt gagaaggcca acgaccgtac cgataagctt gctcaaacgg
     6721 ccgttcttca ccaagttatc gactttggct aggacaaaga gcaacttagt tttttcttga
     6781 taggcggtga tagcttcaac cacttcttca aaagacaagc cctggtcaat caagtcattc
     6841 aatttttcta cgagtaggtc aacttcacca ccagcagata aactatcaat cacatgaatc
     6901 ttagtgtcag gatggtcttc cagataaata ttctttgcta gttgagcact attgtgactg
     6961 ccagaaaggg tacctgtgat ggttactagg aaaatgtttt tggcaccttc aaatgctcgc
     7021 aaatagtcat ctgggcttgg acaagccgat tttgaagctt ctgcagttgc atacatggtt
     7081 tccatcattt ggtcaatatc gagactggcg tcatcaacaa agacctgatc agctacttga
     7141 atggttaagg ggacgcttac aaaggttgtg ttaatagctg gtgttggcag ttgacgataa
     7201 tcacaaccag agtcagcaat aatcttccaa gtcatagaaa ttctccatct ttgtcagtta
     7261 tacattgaca aaggttctgt ctttttttac aattatatca tgaaaaccct tgaaacaaaa
     7321 gcatcatccg tctgttgtga caagtagaaa gaaaatgtta tgtctgaacg tagaatctct
     7381 gaaaagtctc ttgaaaatct cagaaaatca aaccaagaat ccaatttatt aaccagagaa
     7441 gccattgaaa cagccctctt gcaactcttg gaaaaaaagg aactgaccaa gattagtatt
     7501 tctgaattgg tcaaacgtgc aggtgtttcg cgtgcggcct tttatcgcaa ttatgactcc
     7561 aaagaggaaa ttttagagag cgtctttaaa cgaactgtcc acaatattat ggaacagctg
     7621 catcattacg atttaaagac agacctttat ttggtttggg ttcacctttt ccgggaggcc
     7681 agaaaggaag ctagagtaat tcaattggcc ttggattacc atctggaaaa aatctttgtc
     7741 caagccatgc aggaatttct agaaaaatac catgggaaat caaaaggtgt cagctcttat
     7801 cttcattcct tctggagctc agccatcgtc tctgtccttc taaaatggat caaggatggc
     7861 atgaaggtac cagctgaaaa gattgcagat ttaggtttac cattttttaa aaaatagaga
     7921 aaaaggagaa aagagatgac tgaaaaaaga ctggcctggg atgagtattt tgcagcccaa
     7981 gccctactaa ttgcgaatcg ttccacttgt aaacgtgcta aagtgggcgc gattctggta
     8041 aaagataata aggttatttc cactggttac aatggttcgg tgtcagggac tgagcattgt
     8101 attgatcacg aatgtttggt cattgaaggc cactgtgttc gcacccttca cgctgaggtc
     8161 aatgctatcc ttcaaggtgc tgagcgtggt gttcccaaag gctttacagc ctatgtaacc
     8221 cattttcctt gtctcaactg tacaaaacaa ttgcttcagg tcggctgcaa gcgtgtggtt
     8281 tatatcaacc agtaccgaat ggacgactac gcccaatacc tttatcaaga aaaagggaca
     8341 gaattgaccc atttaccact tgagacagta cagacagctc ttaaagaggc tgatctaatg
     8401 taaaaattat caaaaataaa tggtttagaa agatttttaa accgtttttt ggtataataa
     8461 gaagaataaa ttgaaagaag gaattccaaa aatgggaaaa attgaagtta ttaatcaccc
     8521 actgattcaa cacaaattgt caatcttgcg tcgtacagat acttctacaa aagcttttcg
     8581 tgagctagta gatgagattg caatgttgat ggggtatgaa gtacttcgtg atcttccact
     8641 agaagatgtg gaaatcgaaa caccaattac aaaaacagtt caaaaacaat tggcaggtaa
     8701 gaaattggcc atcgtcccaa tcttgcgtgc aggtatcggg atggttgatg gtctcttgag
     8761 cttggttcca gctgctaaag ttggccacat cggtatgtac cgtgatgaag aaacacttca
     8821 accagttgaa tacttggtga aattgcctga ggacattgac caacgtcaaa tttttgtagt
     8881 agacccaatg ttggcaacag gtggctcagc aatcttggct gttgattctc ttaaaaaacg
     8941 tggcgcatca aatatcaaat ttgtctgcct tgtatctgct ccagagggtg taaaagccct
     9001 tcaagaagct catccagatg tagaaatctt tacagcagcc ttggatgaac gtttgaacga
     9061 acacggttat atcgttccag gtcttggaga tgctggagac cgcttgttcg gtacaaaata
     9121 agatcgaaaa gaagaatgac ttggaaaagt atttccagtc acgaaaggag gttgggtttt
     9181 tgtttctgtc taatgaaagc agagcaaaaa tttgaccttt tttgaccaag atattataat
     9241 agtcttatct tcagtcattt gaccaacaaa attaaaactc aaaaggagaa atgaatgatt
     9301 cctgtagtta ttgaacaaac aagccgtgga gaacgttctt acgatattta ctcacgtctt
     9361 ctcaaagacc gcatcattat gctgacaggt ccggttgaag acaatatggc taactctgtt
     9421 attgcccaac tgcttttctt ggatgcccaa gatagtacaa aagatattta cctttatgtc
     9481 aatacaccag gtggttctgt ttcagctggt ttggcaatcg tagataccat gaactttatc
     9541 aaggcagatg tccaaaccat tgttatggga atggctgcat ctatgggaac agtcatcgca
     9601 tcaagtggag caaaaggcaa acgtttcatg cttccaaatg ctgaatacat gattcaccaa
     9661 ccaatgggcg gtacaggtgg tggtacccaa caaactgata tggctatcgc tgcagaacac
     9721 ttgctcaaaa ctcgtaatac cttggaaaaa atcttggctg aaaattcagg tcagtcaatg
     9781 gaaaaagtcc atgcagatgc agaacgtgat aactggatga gcgcccagga aacacttgaa
     9841 tatggcttta ttgatgaaat tatggccaac aattcattga actaatgatg atagaaggca
     9901 aactcgactg ggtttgcttt ttttggtata atagggagag atttcttaga aagaggattt
     9961 atcatgtttg aaaaagtcaa tcgctctggc ttgattatct atctttacta taatcgtgat
    10021 gccaaaaaac tgcaggatta tggagatatt acctatcatt ccaagaaaca tcgttactta
    10081 caactctatg ttccaactca agaagtggag caattggtcg gacgcttgag caaggaaaaa
    10141 tttattaaaa aagttagggt ttgtcatatc caagagttgg aaacaccctt tgtgggcaat
    10201 ctttatcgat aggaaaacgt tatcatcgaa aaagttcaag gaaaacattg acaattttct
    10261 gataattcgg tatattctta acagactatt taagaaataa ggagacaaaa aagatgaaga
    10321 aaaaatttgc cctatcgttt gtggcgcttg caagtgtagc acttcttgca gcctgtggag
    10381 aagtgaagtc tggagcagtc aacactgctg gtaactcagt agaggaaaag acaattaaaa
    10441 tcgggtttaa ctttgaagaa tcaggttctt tagctgcata cggaacagct gaacaaaaag
    10501 gtgcccaatt ggctgttgat gaaatcaatg gcgcaggtgg tatcgatgga aaacaaatcg
    10561 aagtagtcga taaagataat aagtctgaaa cagctgaggc tgcttcagtt acaactaacc
    10621 ttgtaaccca atctaaagta tcagcagtcg taggacctgc gacatctggt gcgactgcag
    10681 ctgcggtagc gaatgctaca aaagcaggtg ttccattgat ctcaccaagt gcgactcaag
    10741 atggattgac taaaggtcaa gattacctct ttattggaac tttccaagat agcttccaag
    10801 gaaaaattat ctcaaactat gtttctgaaa aattaaatgc taagaaagtt gttctttaca
    10861 ctgacaatgc cagtgactat gctaaaggga ttgccaaatc tttccgcgag tcatacaagg
    10921 gtgaaatcgt tgcagatgaa actttcgtag caggtgacac agacttccaa gcagccctta
    10981 caaaaatgaa agggaaagac tttgatgcta tcgttgttcc tggttactat aatgaggctg
    11041 gtaagattgt aaaccaagcg cgtggtatgg gaattgacaa accaatcgtt ggtggtgatg
    11101 gattcaacgg tgaggagttt gtacaacaag caactgctga aaaagcatca aacatctact
    11161 ttatctcagg cttctcaact actgtagaag tttcagctaa agctaaagcc ttccttgacg
    11221 cttaccgtgc taagtacaat gaagagcctt caacatttgc agccttggct tatgattcag
    11281 ttcaccttgt agcaaacgca gcaaaaggtg ctaaaaattc aggtgaaatc aagaataacc
    11341 ttgctaaaac aaaagatttt gaaggtgtaa ctggtcaaac aagcttcgat gcagaccaca
    11401 acacagtcaa aactgcttac atgatgacca tgaacaatgg taaagttgaa gcagcagaag
    11461 ttgtaaaacc ataatagaaa aatgttgaaa cagggaatga gcctttgact cactccctgt
    11521 ttcgatattt aatactcttc gaaaatctct tcaaactgcg tcaacgtcgc cttggattat
    11581 atatgtgact gacttcgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacctg
    11641 cggctagttt cctagtttgc tctttgattt tcattgagta taagaaccta tcaaaaagtg
    11701 agggaaaacc ctcggaatta taaatagaaa gagtgaatct tatgctccaa caactcgtaa
    11761 atggtttgat tctaggtagt gtttacgcgc tgttagccct aggatatacc atggtttacg
    11821 gaattatcaa gctcatcaac ttcgcccatg gtgatattta tatgatggga gcctttatcg
    11881 gttatttctt gatcaattct ttccaaatga atttctttgt agcgcttatt gtagctatgc
    11941 tagcgacagc tattcttggt gtcgtgattg agtttcttgc ttaccgacct ttgcgccact
    12001 ctactcgtat tgctgttttg attacggcta ttggggtttc tttcctattg gagtatggaa
    12061 tggtctatct ggttggtgcc aatacccgtg ccttccctca agcgattcaa acagttcgat
    12121 atgatttggg accaattagc ttaacaaatg tgcagttaat gattttgggc atttccttga
    12181 ttttgatgat tttgttacaa gtcattgtcc aaaagactaa gatggggaaa gccatgcgtg
    12241 cagtatcagt agatagcgac gcggcgcaat tgatggggat caatgtaaac cgtacgatta
    12301 gctttacctt cgctttgggt tctgctcttg cgggtgcggc tggtgttctg attgctcttt
    12361 attataactc tcttgagcct ttgatggggg ttactccagg tcttaaatct ttcgttgccg
    12421 cagtacttgg tggtatcgga attattcctg gtgcggctct tggtggcttt gtgattggtc
    12481 tattggaaac ctttgcgaca gcctttggga tgtcagattt ccgtgatgcc attgtttatg
    12541 gaatcttgtt gttgatcttg attgtccgcc cagctggtat ccttggtaag aatgtgaaag
    12601 agaaggtgta aacgatgaag gaaaatttaa aagttaatat tctatggtta ctccttttgt
    12661 tagctggcta tagcttgatt agtgtactgg tttcagtcgg agtacttaat ctattctatg
    12721 tacagatttt acaacaaatt ggaattaata ttattttggc tgttggtctc aacttaatcg
    12781 ttggtttttc aggacaattt tcacttggtc atgctggttt catggcgatt ggtgcctatg
    12841 cagcagctat tattggttct aaatcaccaa cctacggtgc cttctttgga gctatgcttg
    12901 taggggcttt gctttcagga gcagttgcct tacttgtcgg cattccaacc ttgcgcttga
    12961 agggggacta tcttgcggta gcaactctgg gtgtttctga aattatccgt atctttatca
    13021 tcaatggtgg aagtcttaca aatggtgcgg caggtatctt agggattcct aactttacaa
    13081 cttggcaaat ggtttacttc tttgtcgtga ttacaaccat tgcaaccttg aacttcttgc
    13141 gtagcccaat tggccgttca accctctctg ttcgtgaaga tgaaatcgct gctgagtcag
    13201 ttggggttaa tacgactaaa attaaaatca tcgcttttgt ctttggtgcc attactgcaa
    13261 gtattgctgg gtcacttcag gcaggattta tcgggtctgt tgtaccgaaa gattacacct
    13321 tcatcaactc aatcaacgtt ttgattattg ttgtatttgg tggactcggt tccattacag
    13381 gtgcgattgt ttcggctatt gttctgggaa ttttgaatat gcttctccaa gatgttgcta
    13441 gtgtgcgtat gattatttac gctttggcct tggtattggt aatgattttc agaccaggtg
    13501 gactccttgg aacgtgggaa ctgagcctat cacgtttctt taaaaaatct aagaaggagg
    13561 aacaaaacta atggcattac ttgaagtaaa acagttaacc aaacattttg gtggtctaac
    13621 agctgttgga gatgtgactc ttgaattgaa cgaaggggaa ctggttggat taatcggtcc
    13681 aaacggagct gggaaaacca cccttttcaa ccttttgacc ggtgtttatg aaccaagtga
    13741 gggaacagta accctagatg gtcacctttt gaatgggaaa tcaccttata agattgcctc
    13801 tttgggactt ggacgtactt tccaaaatat ccgtcttttt aaagatttaa cagttttaga
    13861 caatgttttg attgcttttg gaaaccatca caaacagcat gtttttacta gtttcttacg
    13921 cttaccagct ttttacaaga gtgaaaaaga attaaaggct aaagctttgg aattgttgaa
    13981 aatctttgat ttagatggtg atgcagagac tcttgctaaa aatctttcct acggacaaca
    14041 acgtcgtttg gaaattgttc gtgcccttgc tacggaacct aaaattctct tcttagatga
    14101 accagcagca ggtatgaacc cacaggaaac agccgaattg actgagttaa ttcgtcgtat
    14161 caaagatgag tttaagatta caatcatgtt gattgaacac gatatgaatc tggtcatgga
    14221 agtaacagaa cgtatctacg tacttgaata tggccgttta atcgctcaag gaactccaga
    14281 cgaaattaag accaataaac gcgttatcga agcttatcta ggaggtgaag cctaatgtct
    14341 atgttaaaag ttgaaaatct ttctgtgcat tacggtatga tccaagcagt tcgtgatgta
    14401 agctttgaag ttaatgaagg agaagttgtt tcccttatcg gtgccaacgg tgcaggtaag
    14461 acaactattc ttcgcacctt gtcaggtttg gttcgaccaa gttcaggaaa gattgaattt
    14521 ttaggtcaag aaatccaaaa aatgccagct cagaaaatcg tggcaagtgg tctttcacaa
    14581 gttccagaag gacgccacgt ctttcctggc ttgactgtta tggaaaatct tgaaatggga
    14641 gctttcttaa agaaaaatcg tgaagaaaat caagctaact tgaagaaggt tttctcacgc
    14701 tttcctcgtc ttgaagaacg gaagaaccaa gatgcagcca ctctttcagg gggggaacaa
    14761 caaatgcttg ccatgggacg cgccctcatg tcaacaccaa aacttcttct tttagatgaa
    14821 ccatcaatgg gacttgcccc aatctttatc caagaaattt ttgatatcat tcaagatatt
    14881 cagaagcaag gaacaacggt cctcttgatt gaacaaaatg ccaataaagc acttgcaatc
    14941 tctgaccgag gatatgtact ggaaacaggg aaaatcgtcc tatcaggaac aggaaaagaa
    15001 ctcgcttcat cagaagaagt cagaaaagca tatctaggtg gctaaaacaa tccagtggat
    15061 tgttttagtc ggcagatgga gattacgaag taatcatcaa tatagtccgg gggacctttt
    15121 tagtcggtag attgagattg caaacaaatc tgcatctaca ttgaaagctt aatttctaat
    15181 aattgaaaaa atcgaatgaa aaatttctta ccttcattca cagagctcga tttcagagct
    15241 ctttttgcta gcttattcat acttttttga atttcgaaaa agaaatgtaa gcgtttgata
    15301 gatttacaaa aagattgtat aatggggata agaatagaaa aggagaagtc tcatggcagt
    15361 taaagatttt atgacccgca aggtagttta tattagtcca gatacaacag tatctcatgc
    15421 agcagatttg atgagagagc aaggattgca ccgcttgcct gttatcgaaa atgatcaatt
    15481 ggttggtttg gtgactgagg gaaccattgc acaagcaagt ccatctaaag caacaagtct
    15541 ttctatctat gagatgaatt atcttctgaa taagacaaaa gtaaaagatg tcatgattcg
    15601 cgatgttgtc actgtctcag gctatgctag tctagaagat gcaacttatc tgatgttgaa
    15661 aaataagatt ggtattctcc ctgtcgtaga taaccatcaa gtatacggag ttattactga
    15721 ccgtgacgtt ttccaagcct ttcttgaaat tgcaggttat ggcgaagaag ggattcgtgt
    15781 acgctttgtt acagaagatg aagttggtgt tcttggaaaa attatttctt tgattgtaga
    15841 agaaaatttg aatatatccc atacagtcaa tattccgcgt aaggatggta aggtcattat
    15901 cgaagtgcaa atcgatggat caattgattt accagccttg aaagaaaaat ttgaagcaaa
    15961 tggtattcaa gtggaagaaa tcgctcgcac ttcagcaaaa gtcttgtaag aagggaagcc
    16021 aaaggcttct tttttcatga aaaggggatt agagcaaaag atggaaagaa atgataaaat
    16081 atgctataat gaaataatgt aaaaaaggag tatttatgga catttcagta attcgtcaga
    16141 aaattgacgc aaatcgtgaa aaattagctt ctttcagggg gtctctttga cctcgaaggg
    16201 ctagaggaag agattgccat cttggaaaac aagatgacag aacctgattt ttggaacgat
    16261 aatattgcgg cccaaaaaac gtcgcaagaa ttgaatgaat taaaaaacac ttacaatacc
    16321 ttccataaga tggaagagtt gcaggatgaa gtcgaaattt tattggattt tttggctgaa
    16381 gacgagtcag tgcatgatga actggtagcg cagttagccg aacttgataa gataatgact
    16441 agttacgaga tgactctact cttgtcagaa ccttatgacc acaacaatgc catcttggaa
    16501 atccatccag gttctggtgg tactgaggcg caggactggg gtgatatgtt gcttcgtatg
    16561 tatactcgtt atggtaatgc taaaggcttt aaagtggaag tgttggatta ccaagcaggt
    16621 gatgaggctg gtattaagtc ggtaacttta tcatttgaag ggcctaatgc ctatggtctc
    16681 ctcaagtcag aaatgggtgt tcatcgctta gtgcgaatct caccatttga ctctgccaaa
    16741 cgtcgccata cctctttcac atctgtagaa gtgatgccag aattggatga tactattgaa
    16801 gtggaaatcc gtgaagatga tatcaagatg gataccttcc gttcaggtgg tgccggtgga
    16861 caaaacgtca ataaagtttc aacaggtgta cgtttaaccc acattccaac tggaattgtt
    16921 gtccaatcaa cagtggatcg tacccagtat ggaaatagag atcgtgccat gaagatgttg
    16981 caggctaagc tctatcaaat ggagcaagat aagaaggctg cggaggtaga ttctctcaaa
    17041 ggtgagaaaa aggagatcac ttggggaagc caaatccgtt cttatgtctt cacgccttat
    17101 actatggtaa aagatcaccg aactagcttt gaggttgctc aggtagataa ggttatggat
    17161 ggggacctag atggttttat cgatgcttat ctcaagtggc gaattagcta agatagaaag
    17221 gaactcacat gtcaattatt gaaatgagag atgtcgttaa aaaatacgac aacggaacga
    17281 ctgctctacg cggtgtttcg gttagcgttc aaccggggga atttgcctac atcgtaggac
    17341 cttcaggagc agggaagtca acttttattc gttctctgta tcgtgaagta aaaatcgata
    17401 aaggaagcct atcagttgct ggttttaatc tggttaagat caaaaagaaa gatgtcccgc
    17461 ttctacgtcg tagtgttggg gttgtcttcc aggattataa actgttacca aagaaaactg
    17521 tctatgaaaa tattgcttac gctatggaag taatcgggga aaatcgccgt aatatcaaaa
    17581 gacgagtgat ggaagttttg gacttggttg gattgaagca taaggttcgt tcttttccaa
    17641 atgaactctc aggtggggag cagcagcgga ttgcgattgc gcgtgcaatt gtaaataatc
    17701 ccaaagtatt gatagctgat gagccaacag gaaatctgga tccggataat tcatgggaaa
    17761 ttatgaatct cttggaacgg attaacctac aaggaacaac tattttgatg gcgactcata
    17821 atagccagat tgtaaatacc ttgcgccacc gtgtcattgc cattgaaaat ggccgtgtcg
    17881 ttcgtgacga atcaaaagga gagtatggat acgatgatta gtagattttt tcgccattta
    17941 tttgaagcct taaaaagttt gaaacgaaat ggttggatga cagtagctgc tgtcagttca
    18001 gtcatgatta ctttgacctt ggtggcaata tttgcatctg ttattttcaa tacagcgaaa
    18061 ctagctacag atattgaaaa taatgtccgt gtagtagttt atatccgaaa ggatgtggaa
    18121 gataatagtc agacaattga aaaagaaggt caaactgtta caaataatga ctaccacaag
    18181 gtatatgatt ctttgaagaa catgtctgcg gttaaaagtg ttaccttttc aagtaaagaa
    18241 gaacaatatg aaaaattaac cgagataatg ggagataact ggaaaatctt tgaaggagat
    18301 gccaatcctc tctatgatgc ttatattgta gaggcaaaca ctccaaatga tgtaaaaact
    18361 atagccgaag atgctaaaaa aattgaaggt gtctctgagg ttcaagatgg cggtgccaat
    18421 acagaaagac tcttcaagtt agcttcattt atccgtgttt ggggactagg gattgctgct
    18481 ttgttaattt ttatcgcagt tttcttgatt tcaaatacca ttcgtattac cattatttcc
    18541 cgcagtcgcg aaattcaaat catgcgcttg gtcggagcta aaaacagtta tatccgtgga
    18601 ccgttcttgt tagaaggagc ctttatcggt ttattgggag ctatcgcacc atctgttttg
    18661 gtctttattg tttatcaaat tgtttaccaa tctgtcaaca aatcgttggt agggcaaaat
    18721 ctatccatga ttagtccaga tttatttagt ccgttgatga ttgccctact atttgtgatt
    18781 ggggttttca ttggttcatt gggatcagga atatccatgc gccgattctt gaagatttag
    18841 gtaaaatagc tgcttttatg aggagattgt aaaatctcct tttttgctac aagagttttt
    18901 gaaaagagat tccaaagaag tcccccagag aagacttctt gatggctaat ttgaacttga
    18961 aatttggcgc actagaaatt ttttagaaaa aagtgtaatt tttttataaa agcctttaca
    19021 aaaaaaatta aagtggtata attaaatcat agaaagtgca aacgttttcg taaaacgttt
    19081 gcctaaataa aaataaagga gatttgaatg atgaaagata cattcaaaaa tgtcttgtct
    19141 ttcgaatttt ggcaaaaatt cggtaaggct ttgatggtag ttatcgcggt tatgccggct
    19201 gctggtttga tgatttcaat cggtaagtct atcgtgatga ttaacccaac ctttgcacca
    19261 cttgtcatca caggtggaat tcttgagcaa atcggttggg gggttatcgg taaccttcat
    19321 attttgtttg ccctagccat tggaggaagc tgggctaaag aacgtgctgg tggtgctttc
    19381 gccgctggtc ttgccttcat cttgattaac cgtatcactg gtacaatctt tggtgtatca
    19441 ggcgatatgt tgaaaaatcc agatgctatg gtaactactt tctttggtgg ttcaatcaaa
    19501 gttgctgatt actttatcag tgttcttgaa gctccagcct tgaacatggg ggtattcgta
    19561 gggattatct caggttttgt aggggcaact gcttacaaca aatactacaa cttccgtaaa
    19621 cttcctgatg cactttcatt cttcaacggg aaacgtttcg taccatttgt agttattctt
    19681 cgttcagcaa tcgctgcaat tctacttgct gctttctggc cagtagttca aacaggtatc
    19741 aataatttcg gtatctggat tgccaactca caagaaactg ctccaattct tgcaccattc
    19801 ttgtatggta ctttggaacg tttgctcttg ccatttggtc ttcaccacat gttgactatc
    19861 ccaatgaact acacagctct tggtggtact tatgacattt taactggtgc agctaaaggt
    19921 actcaagtat tcggtcaaga cccactatgg cttgcatggg taacagacct tgtaaacctt
    19981 aaaggtactg atgctagtca ataccaacac ttgttagata cagtacatcc agctcgtttc
    20041 aaagttggac aaatgatcgg ttcattcggt atcttgatgg gtgtgattgt tgctatctac
    20101 cgtaatgttg atgctgacaa gaaacataaa tacaaaggta tgatgattgc aacagctctt
    20161 gcaacattct tgacaggggt tactgaacca atcgaataca tgttcatgtt catcgcaaca
    20221 cctatgtatc ttgtttactc acttgttcaa ggtgctgcct tcgctatggc tgacgtcgta
    20281 aacctacgta tgcactcatt cggttcaatc gagttcttga ctcgtacacc tattgcaatc
    20341 agtgctggta ttggtatgga tatcgttaac ttcgtttggg taactgttct ctttgctgta
    20401 atcatgtact ttatcgcaaa cttcatgatt caaaaattca actacgcaac tccagggcgt
    20461 aacggaaact acgaaactgc tgaaggttca gaagaaacca gcagcgaagt gaaagttgca
    20521 gcaggctctc aagctgtaaa cattatcaac cttcttggtg gacgtgtaaa catcgttgat
    20581 gttgatgcat gtatgactcg tcttcgtgta actgttaaag atgcagataa agtaggaaat
    20641 gcagagcaat ggaaagcaga aggagctatg ggtcttgtga tgaaaggaca aggggttcaa
    20701 gctatctacg gtccaaaagc tgacattttg aaatctgata tccaagatat ccttgattca
    20761 ggtgaaatca ttcctgaaac tcttccaagc caaatgactg aagcacaaca aaacactgtt
    20821 cacttcaaag atcttactga ggaagtttac tcagtagcag acggtcaagt tgttgctttg
    20881 gaacaagtaa aggatccagt atttgctcaa aaaatgatgg gtgatggatt tgcagtagaa
    20941 cctgcaaatg gaaacattgt atctccagtt tcaggtactg tatcaagcat cttcccaaca
    21001 aaacatgctt ttggtattgt gacggaagca ggtcttgaag tattggttca cattggtttg
    21061 gacacagtaa gtcttgaagg taaaccattt acagttcatg ttgctgaagg acaaaaagtt
    21121 gcagcaggag atctccttgt cacagctgac ttggatgcta tccgtgcagc aggacgtgaa
    21181 acttcaacag tagttgtctt cacaaatggt gatgcaatta aatcagttaa attagaaaaa
    21241 acaggttctc ttgcagctaa aacagcagtt gctaaagtag aattgtaata tacttgaggt
    21301 tggaagctgt attccaacct cttattttgg gagaaaagaa tgaaattttt aacactcaat
    21361 actcacagtt ggatggagaa agaagcagag gaaaaattcc agattttgct tgaagatatt
    21421 cttgaaaagg actatgattt gatttgtttt caagaaatca atcaggagat gacctcgtca
    21481 gaggtggagg ttaatgacct ttatcaagct ttgccagcag ctgagcctat tcaccaagac
    21541 cattatgtta gactcttggt tgaaaagttg ttagagcaag ggaaaaatta ctactggacc
    21601 tgggcttata accatatcgg ctatgaccgc taccacgaag gtgtggctat cttgtctaaa
    21661 acacctattg aagccagaga aattttggtt tcagatgtgg atgatccaac agactatcat
    21721 actcgccgtg ttgccctagc tgaaactgta gttgatggca aggagctagc agttgccagt
    21781 gttcatctct cttggtggga taaaggtttc caagaagaat gggcacgatt tgaggctgtt
    21841 ttgaaaaaat tgaacaagcc acttttacta gctggagatt ttaacaaccc agcaggtcag
    21901 gaaggttacc aagctatttt agctagtcca ttaggcttac aagacgcatt tgaagttgct
    21961 caagagaaaa gtggtagcta tactgttccg cctgaaattg atggctggaa agggaacact
    22021 gaaccccttc gaatcgatta tgtctttact accaaagagt tagcggtgga aaatttacat
    22081 gtcgtatttg atggtaacaa gagtccacaa gtgagtgatc actatggctt gaatgctatg
    22141 ttaaactgga aataataact gaaaagaggt tggaactata aaattccagc cttttcttac
    22201 tagagaagct actggaaata gcctaaataa gtgagactac tgtaatggaa taaaatatgg
    22261 tataattgat aagatagata gaatcgagga tgttatgtca tttacgaaat ttcaatttaa
    22321 aaactatatt agagaagcct tgaaggagtt aaaatttaca actccaacag aggtgcaaga
    22381 caagttgatt cctattgttt tggcaggtcg tgacctagta ggagaatcaa aaacaggttc
    22441 aggtaagact catactttct tgttaccgat tttccagcaa ttagatgaag ctagcgatag
    22501 tgtgcaagca gtgattactg caccgagtcg tgagttggct actcaaattt accaagtagc
    22561 gcgtcagatt tcagctcact cagatgtcga agttcgtgtg gttaattatg tgggtggtac
    22621 ggataaggct cgccagattg agaaattggc aagcaatcag cctcatattg ttattggaac
    22681 accaggccgt atctacgact tggttaaatc tggtgattta gctattcata aagccaagac
    22741 atttgttgtt gatgaagcag atatgacctt ggatatggga ttcttggaaa ctgttgataa
    22801 gattgctggc agtcttccaa aagacttgca attcatggtc ttctcagcga ctatcccaca
    22861 aaaactgcaa ccattcttga aaaaatactt atcaaatcct gttatggaga aaattaagac
    22921 caaaacggtt atttctgaca ccattgataa ttggttgatt tcgaccaagg gacatgataa
    22981 gaatgctcaa atttaccagt tgactcagtt gatgcagccg tatttggcaa tgatttttgt
    23041 taacactaaa acgcgtgctg atgaattgca ttcatatctg actgctcaag gcttgaaggt
    23101 tgcaaaaatc catggagata ttgcccctcg tgaacgcaag cgaatcatga atcaggtgca
    23161 aaatctggat tttgagtata ttgtcgcaac agatttggca gcgcgtggga ttgacattga
    23221 aggtgtcagc catgtcatca atgatgccat tccgcaagac ttatcttttt ttgttcatcg
    23281 tgttggtcgt actggacgaa atggcctacc aggtacagct attacccttt atcagccaag
    23341 tgatgactcg gatatccgtg agttggagaa attggaaatc aagtttagtc ctaagatggt
    23401 caaagacggg gaatttcaag atacctatga ccgtgatcgt cgtgccaacc gtgagaaaaa
    23461 acaagataaa cttgatatcg aaatgattgg tttggttaaa aagaaaaaga aaaaagtcaa
    23521 accgggttat aagaagaaaa ttcaatgggc ggttgatgaa aagcgccgta aaaccaagcg
    23581 tgctgaaaat cgcgctcgcg gtcgtgcaga gcgtaaagct aaacgccaaa cattttaata
    23641 gaaattgttg gagtattgag ctccaacttt ttgctttatg agaacgaact atctaaaccg
    23701 aaacactaca ttaaagactg caaattgcga ttaaaaatgg tataatgata aagttatata
    23761 gtcccgataa gatggtaggt atttattacg aagagttttc ctatcagtac tttgtaactc
    23821 tataacaata ttttttaagg ggggacattt ttatgtcaga acgtaaatta ttcacgtctg
    23881 aatctgtatc tgaggggcat ccggataaga ttgcagacca aatttcagat gcgattttgg
    23941 atgctatttt agcaaaggat ccagaggcgc acgttgctgc tgaaacagct gtatatactg
    24001 gttctgtcca cgtttttggt gaaatttcta caaatgccta tgtggatatt aaccgtgtgg
    24061 ttcgtgatac cattgcagag attggttata ccaatacaga atatggattt tctgctgaga
    24121 cggtgggagt acacccatct ttggtggaac aatctcctga catcgctcaa ggtgttaacg
    24181 aagccttgga ggttcgtgga aatgctgatc aagatccact ggacttgatt ggagcaggtg
    24241 accaagggct catgtttgga tttgcagtag atgaaacaga agagctcatg ccattgccaa
    24301 ttgcactcag tcataaattg gttcgtcgtc tggcagaact tcgtaagtct ggagaaatta
    24361 gctatctccg tccagatgca aaatcacaag ttacagttga gtacgatgaa aatgaccgtc
    24421 cggtacgtgt agatacagtc gttatttcta ctcagcatga tccagaggcc actaatgaac
    24481 aaatccatca agatgtgatt gacaaggtca tcaaagaagt tattccatct tcttatcttg
    24541 atgataagac aaaattcttt atcaatccga caggtcgttt tgtaatcggt ggtcctcaag
    24601 gggactcagg tttgactggt cgtaagatta ttgtagatac ttatggtggc tactctcgtc
    24661 atggtggtgg tgccttctct ggtaaagatg cgactaaggt ggatcgttca gcctcttatg
    24721 cggctcgcta tattgccaag aatatcgttg cagcagacct tgctaagaag gcagaagtgc
    24781 agttggccta tgctatcggt gttgcgcaac ctgtttctgt tcgtatcgat actttcggta
    24841 caggaacagt agctgaaagt caacttgaaa aagcggctcg tcaaatcttt gaccttcgcc
    24901 ctgcagggat tatccaaatg ctggacctta agcgtccaat ttaccgtcaa acatcggctt
    24961 acggtcacat gggacgtaca gatattgatc ttccatggga acgtttggat aaggtagatg
    25021 ctttgaaaga agcagtaaaa taagatttta agaggggaac gtcctctctt ttttatagtt
    25081 tttaactata ctgggatact gttctgaaaa tccattttgc gaaagtagag atttacatgt
    25141 atagtagatt gaaactaaaa tagtacactt gaacttctaa aacattgtta gaaatcgatt
    25201 tgactgtcct gatcgatttc tcctgttctt gtttcatttt actatatttc tttaaaaatg
    25261 ataaaggttg agatttctcc ttgttgcttg gacttcattc aaaagtctgt tacccaagcc
    25321 ttgttcaaac ttccaataca ctagctgttt ccatagcatg acttctgtac tagactttct
    25381 tttccgaata aatagataga accacagaat ctagtaaacc tagaattaaa attatggtat
    25441 aatattagca ataaaagaaa tctggaggat tagaatcatg gtatcaacga aaacacaaat
    25501 tgctggtttt gagtttgaca attgcttgat gaatgcagca ggtgtggctt gtatgacgat
    25561 aaaggagtta gaagaggtca aaaactcagc ggcaggaacc tttgttacta agacagcgac
    25621 cttggatttc cgtcagggga atcctgagcc acgctaccaa gatgttccac ttggttccat
    25681 caactctatg ggcttgccaa ataatggctt agactattat ttggattatc ttttagattt
    25741 gcaggaaaaa gagtcgaacc gaactttctt cttatctctg gtcggcatgt ctccagagga
    25801 aacccatact attttgaaaa aagtccaaga gagtgatttt cgtggtctga ctgagctaaa
    25861 tctttcctgt ccaaatgttc caggtaaacc tcagattgcc tatgattttg agacaacaga
    25921 ccggattttg gcagaagtgt ttgcttactt caccaaacct cttggaatta aattgccacc
    25981 ttattttgat attgttcact ttgaccaagc ggcagctatt ttcaacaaat atccgctcaa
    26041 gtttgtcaac tgcgttaact ctatcggaaa cggcctctat atagaagacg agtctgtcgt
    26101 tattcggcct aagaatggtt ttggtggaat tggtggagaa tacatcaaac cgactgctct
    26161 agccaatgtt cacgcctttt atcaacgttt aaatcctcaa atccaaatta tcggaacagg
    26221 tggcgttctg actggtcgag atgcctttga acacatcctc tgtggagcaa gtatggtgca
    26281 ggtgggaacg acccttcaca aagaaggcgt cagtgctttt gaccgcatta ccaatgaact
    26341 gaaagcaatc atggtggaaa aaggctacga gagcttagaa gatttccgtg ggaaattgcg
    26401 ctatattgac taaattaaat cgaaaaatct gaagaaagga gagacgatgc tagccattga
    26461 agaaagtcag aagttgactt tatcaaattt accgagcctg agcctattta cagggacaga
    26521 tcagggtcag tttgaagtga tgaagagtca aatgttgaaa cagattgggt atgattctgc
    26581 tgacctcaac tttgcctact ttgatatgaa agaagtagtt tacaaggatg tggaactgga
    26641 gttggtcagc cttcctttct ttgcggatga gaaaatcgtg atattagatt attttatgga
    26701 tatcacgact gctaagaaac gctttttgac agatgatgag cttaagtcat ttgaggaata
    26761 ccttgacaat ccttctccaa caaccaagtt gataatcttt gcagaaggaa agctggatag
    26821 caaaagacgg ttagtcaaat tacttaagcg tgatgccaag gccttcgatg cagtagaagt
    26881 aaaagaacaa gaattgcgcc agtacttcca aaagtggagt cagaaacaag gtctgcagtt
    26941 taccaatcat tcttttgaaa atctcctcat caagtcgggg tttcaattta gcgaaatcca
    27001 gaaaaatctt ctctttttac agtcctataa ggtggattct gttatcgagg aagaggatat
    27061 tgttaacgca attcccaaga ccttgcagga caatattttt gatttaactc agtttattct
    27121 gactaaaaag atggatcagg cgcgcgattt ggtgagagac ttgaccttgc aaggggaaga
    27181 tgaaatcaaa ctgattgcag tcatgctggg acaatttcgg acttttactc aggtgaagat
    27241 tttggcggag tctggccaaa cagaatcgca gattgcaagt agtttaggta gttatctggg
    27301 acgtaaccca aatccttacc aaatcaagtt tgcattaaga gattcgagag gactttcttt
    27361 gagctttctg aagcaagcta tttcctattt gattgagaca gactatcaga ttaagacagg
    27421 tctttatgaa aaaggtttcc tttttgaaaa ggcactctta cagattgcta gtcaggtcaa
    27481 ttgacatttg ttgaaactac aacccgcgcc aggattatct tgtcgtgggt ttcttgctga
    27541 tttgcttatt ttattagaaa gtatgtcagt gatttgctta tctataagca aaaaacttga
    27601 aaaaagtgaa tgtttgcgtt atcattttca tatagaaaga aaaagaggta ttacagatgg
    27661 ctattatctt accagaactt ccatatgcat acgacgcttt ggaaccatac atcgatgcgg
    27721 aaacaatgca tttgcaccat gacaaacacc atcaaactta tgtcaacaat gccaatgcag
    27781 ctttagaaaa acaccctgaa atcggtgaag accttgaagc cttgcttgct gatgtagaat
    27841 ctatcccagc tgatatccgt caagcactta tcaacaatgg tggcggacac ttgaaccacg
    27901 ctcttttctg ggaattgatg actcccgaga aaacagctcc ttcagcagag ctggcagcag
    27961 caatcgatgc aacatttggt tcatttgaag aattccaagc agccttcact gcagcagcaa
    28021 caactcgttt tggttcaggt tgggcatggt tggttgtcaa caaagaaggg aaacttgaag
    28081 tgacttcaac agcaaaccaa gacacaccaa tctcagaagg taaaaaacca atcttgggct
    28141 tggacgtttg ggaacatgct tactacgtga aataccgcaa cgtgcgtcct gactacatca
    28201 aagctttctt ttcagtaatc aactggaata aagtagatga attgtacgca gctgctaaat
    28261 aatgatagtt ggagggaaga attgttcttc tcttttttag gttataagat tctggtctga
    28321 caaaatcgtc agactttttt catttttatg agaaacgtgc taactgctag aaattatggt
    28381 agaataaagt attaagtaat cgtggaaaaa ggatatctat gcgaaaagaa attgcacctg
    28441 aattatacaa ctataacaag tttcctggtc cggagttcca tttacacggg gacaaggtcg
    28501 aaacggaagg gatagctttt tccttggttg aaaatatcaa ggatgccttt gatgtgacga
    28561 cttttaatca gcgtttttca gaagtattaa ccaagtttga ttatatcgtg ggggactgga
    28621 gcaacgaaca gcttcgccta cgaggttttt acaaggatga ccgaacagaa gaaaaacttg
    28681 aaaaaatcag ttgtttacaa gactaccttt tagagtattg tagttatggt tgtgcctatt
    28741 ttgtcttaga aaatgaagcc cctaagcgag catcatttga caagaaaatg cgtaagacgg
    28801 aagaagaaac accttctaga aaaggaaaga aaccgactca aactaaacga aagtcgaatg
    28861 cagataagaa aaatagacgt cgtcagaaag accagcattc tcataaagag gacaagggac
    28921 aacgtcattt tgtcattcgt cagaagtgag tagagaataa ggagaagaaa tgaaaccctc
    28981 aattcatagt ttggcacatc aaaccatgca ggaatgggta ttggagcagg gagaaaagaa
    29041 attccgtgca gatcaaatct gggaatggct ctaccgtaaa cgtgtgcagt catttgaaga
    29101 aatgaccaac ctttccaagg atttgattgc taagctcaat gaccagtttg tggtcaatcc
    29161 cttgaaacaa cgtattgtgc aagagtctgc tgatggtaca gtcaaatatc tctttgaatt
    29221 gcctgacggt atgttaattg aaactgtact catgcgtcaa cactatggtt tatctgtctg
    29281 tgtgaccact caggtcgact gtaatatcgg ttgtaccttc tgtgcctctg atttgattaa
    29341 gaagcaacgt gacctcaata acggtgaaat cgtagcgcaa atcatgctgg ttcagaaata
    29401 ctttgctgag cgtggtcagg atgaacgcgt cagccatatc gttgtcatgg gaatcggtga
    29461 gccctttgat aattacaaca atgtcttgaa tttcgtttgt actatcaatg atgataaagg
    29521 aatggctatc ggtgctcgtc acatcacggt ttcaacctca ggtttggctc ataaaattcg
    29581 taactttgct gatgaagggg ttcaggtcaa tcttgccgtg tctcttcacg cacccaacaa
    29641 tgaacttcgt tcaagtatca tgaagattaa ccgtgccttt ccgattgaaa aactctttgc
    29701 tgctattgaa tactacattg agacaacaaa ccgtcgtgta acctttgaat atatcatgct
    29761 taatgaagtc aacgacggtg tagaacaagc cttggaattg gctgaattgc tcaagaacat
    29821 caagaaattg tcttatgtaa acttgattcc ttataaccca gttagtgagc atgaccaata
    29881 tagccgtagt cccaaagagc gcgtgttggc tttctatgat acgcttaaga aaaaaggggt
    29941 caactgtgtg gttcgtcaag agtatggtac agatattgac gcagcttgtg gacaattgcg
    30001 ctctaacaca atgaaacgtg accgccagaa ggcagtcgca gaggtaaatc cgtaaaatga
    30061 ctaaaaaaag agaattaatc ttaagattgg gagtggctgt ttatagccta tgcattgtct
    30121 atttttgctt tactcctcaa gctaccgtgg aagtgggaac tccaggtatt cagcatcttg
    30181 gacgcctggt ttttcttttg actcctttca attctctctg gaaactgggc gaagtgagtg
    30241 acattggaca attatgttgg atttttttac aaaatatcct caatgtcttc ttgttttttc
    30301 ctctgatttt ccaactcctt tatctatttc caaatttgcg gaaaacaaaa aaggtccttc
    30361 tttttagttt tcttgtgagt cttggaatcg agtgtacgca attaatcttg gactttttct
    30421 ttgatttcaa tcgcgtcttt gagattgatg atttgtggac caacactttg ggtggctatc
    30481 tggcttggct cctttataaa cgattacata aaaacaagat aaggaattaa aatgagtatt
    30541 ttagaagtta aaaatctgag tcacggtttt ggtgaccgtg caatttttga agatgtgtcc
    30601 ttccgtctcc tcaagggaga acatatcggc ttggtcggtg ccaatggtga aggaaaatca
    30661 acctttatga gtatcgtgac tggtaaaatg ctgccagatg aaggaaaggt tgagtggtcc
    30721 aaatatgtga cggctggtta cttggatcag cactctgtcc ttgctgaaag acagtcggtg
    30781 cgtgatgttc tccgtacggc ttttgatgag cttttcaaag ctgaagctcg tatcaatgac
    30841 ctctatatga aaatgactga agacggtgcg gatgttgatg ctctcatgga agaagtagga
    30901 gaacttcaag accgtctgga gagtcgtgat ttctatatct tggatgctaa gattgacgaa
    30961 gtagcgcgtg ctcttggtat tatggacttt ggcatggata cggatgtaac ttctttgtca
    31021 ggtgggcaaa gaaccaaggt gcttttggca aaacttctcc ttgaaaagcc tgatattttg
    31081 ctgttggacg agccgaccaa ctacttggat gctgagcata ttgattggct caagcgctat
    31141 ctccaaaact atgagaatgc ctttgttctc atttcgcacg atattccatt cctcaatgac
    31201 gttatcaata ttgtctatca tgtggaaaat caacagctga cgcgttactc tggtgactac
    31261 taccagttcc aagaagttta tgctatgaaa aaatctcagc tagaggcagc ctacgaacgc
    31321 cagcagaaag agattgcaga cctcaaggac tttgtggctc gtaataaagc ccgtgttgca
    31381 actcgtaata tggctatgtc tcgtcaaaag aaattggata agatggatat tatcgaactc
    31441 caaagtgaga aaccaaaacc atcctttgat ttcaaaccag ctcgtacacc agggcgcttt
    31501 atcttccaag ccaagaactt gcaaattggt tacgaccgtc ctcttactaa gtctttaaat
    31561 cttaccttcg aacgcaatca aaaggttgcg attattggtg ctaatggtat tggaaaaaca
    31621 actctcttga agagtctctt gggcattatc tcgccaatcg ctggggaagt ggagcgtgga
    31681 gattatttag aacttggtta ttttgagcag gaagtagaag gtggtaatcg ccaaactcct
    31741 cttgaagctg tctggaatgc ctttcctgcc cttaatcaag cagaagtccg tgcagccctt
    31801 gcccgttgtg gtttgacaac caaacatatt gaaagccaga ttcaagtatt atcaggggga
    31861 gagcaagcca aggttcgttt ctgtctcttg atgaatcgtg aaaacaacgt tttagtgctg
    31921 gacgagccga ccaaccattt ggatgtggat gcaaaggatg agctcaaacg cgctctcaaa
    31981 gaatacaggg gatctatcct tatggtctgc cacgagccag acttttatga aggttggata
    32041 gaccaaatat gggattttaa taatttaact taagaatgag agtaaaagaa atacagtacc
    32101 gaatgtggat actgtatttt tttggttttt aagatttaaa atcgtagtct ttcaccactt
    32161 cgatgctgtc gattgtgata gcagtagttg gcttgtcttt ttcatctttt tcggctttag
    32221 caatcttatc cacaacatcc ataccgtcaa tcacttgacc aaagactggg tgtttgccgt
    32281 ctagactagg gtttccacct tctttgtagg cttcgataat tttctgtgga tacttgcttg
    32341 tagggagttt agaagaggta tctgtagagt tttggttgat gaagaactgg ctgccattgg
    32401 tgtttggttg accagtatta gccatagcaa gagcaccacg gatgttatac aaataaggag
    32461 taatctcgtt cttgaaacca gttcctttgt ctttagtctt atccttgtca tgccagatgg
    32521 actgaccacc tgtaccgtcc ccttttggat ctccagtttg gaccataaag ccatcgatga
    32581 cacggtggaa ggtaataccg ttatagtagc cttctttggc gtgagtgagg aaattttcaa
    32641 ccgctagagg agcgagttta gggaagagtt taatgcgaat atcaccttgg cttgtgtgga
    32701 gaatcacttc ggcttcatct tcagcaactt ccttagatag ttgtgggaaa ttggcgtttt
    32761 cgtttgttaa agcatggttt aactccttgg cagattgggc agctactttg gaactttctt
    32821 cagcagcaag actggaatca acataatcat caccacgcag actgcgttgg acgctgctac
    32881 acccagctag ggctacagta gacagtaaaa gaagggttgc tagttttttc attctgttcc
    32941 tctcaaaaat tcatttatac cattgtaccc taaaaggaag tggatttcaa atattagtag
    33001 tttacagaac tggcttagat aatagttggg atttcatcat catcttgaaa atcttcaact
    33061 tcttccccag taaatggttt ctgaaaagaa cttagtataa aacgggcaat tggttcaaca
    33121 attaggaaat ttagaggaag agctgcaata aagtttacga accaggcgct tagataggta
    33181 ttgggtgtga tagcaatgcc attgtaaaaa agtccataga aggacatgaa agtgaccagc
    33241 taattcttct tctgaaaaat gctcatgaag ggcttgatcc aggtcgcaag atttcatttt
    33301 agaaagtcca gtaattccct tcttcttcag gatattcttt ttcatggtag tatttagatg
    33361 gtcaagtgag tcaaaagaag tttcgacaag agcataccct ttttctacca gagtttttag
    33421 atgtttaggg ggcatcaata ccataagtgt actcaaagta ttttggaaac cagatcttaa
    33481 gaaagctcgt aaagctagtc agttctctaa acgctaagaa ctagctacaa cacagcattt
    33541 acaacacttc atggttcaca ccatggggtg ttttttaatg attttaagca aaattcacac
    33601 ttaattgaaa gttatttaaa ttagatgaaa atttattttt tgaaaaagtg ggaaaacatt
    33661 gattctaagc gaattttgaa tcatattcga atgggagttt ttaaaatcat gtttcagtgg
    33721 taaaagtacc aaactggatt ctccatagta aaatgatatc tcctgctagt gaatcatctg
    33781 ctaataagtc catatttcgc ttgggaacgg gcttgggact taggagccaa gtatccaaat
    33841 ctcgttcagg cgatatgaag ggtttgactt ggtgttcttt ataaaatttt tctaaaatag
    33901 tattcacgga tagcatcttt caaacattta tttcctattc taacaaattt ctaaatactt
    33961 taagaaattt atagtctgtc aagttttttt cttgacacat gccagaaatc tgctataata
    34021 gaacatgtgc taaatagctc agctatttca ccgaaataaa aaattaaaga aatgagactt
    34081 taaaaatggc agttaaaatc cgtttgactc gtatgggttc taagaaaaaa cctttctacc
    34141 gtatcaacgt agcagattca cgttcaccac gtgacggacg tttcatcgaa acagttggaa
    34201 cttacaaccc acttgttgct gaaaaccaag taactttgaa agaagaccgc gttcttgcat
    34261 ggttggctaa tggagctcaa ccttcagaca cagtacgtaa catcctttca aaagaaggcg
    34321 tattgaaaaa attccacgat tctaaattct caaaataagt ttaaagtagg ttgacagatg
    34381 gatacgattg aaaatctcat tattgcgatt gtgaaaccct taatttcaca accagatgcc
    34441 ttaactatca agattgaaga tacaccagaa tttttggaat atcatttgaa tcttgatcaa
    34501 agcgatgtgg gtcgtgtaat cggtcgtaag ggtcgcacta tttctgcgat aagaacgatt
    34561 gtctactctg tcccaactga atacaaaaaa gtaagaatcg ttattgacga aaaataagaa
    34621 gggcgggacg gatgtctcgc ttttttgtgt ggaatagaag atatagtaaa atgaaataat
    34681 gacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtaaagg
    34741 tgtactattc tagtttcaat atactataaa agattgaacg tttaggcaat tccaagacta
    34801 cttactcgaa cattaacagc agtctcggac tgatgaaggt ctctttatga agttagtgga
    34861 ggaagtcgga gaagtagccg aggttttgaa taggcgctct ggtcgaaaag aagggatagg
    34921 attcgaacga ggaacctgcc atagaactgg ctgatatcat tcactacacc gtcgctattg
    34981 ctgttatcaa gcatattgac ctaactagaa ccatctttga gaaagacaaa accgcagccg
    35041 ttaattacca acataaacat gatttggaag gattcttgaa gggaaagtag agatgttgtc
    35101 cccttcctcc aacttgagaa aatctttgga acgtgataaa ataaaggata aggattttta
    35161 ataattcatt atatagaatg agtggatttc tttatgaaga ggtttgaagt atctacagaa
    35221 attggtagcc tctctgttac ttatcaaaaa caaaagaaag tgctagtttg tctaaacgga
    35281 gcaggtttgc taccaagtta tgaaaatttt tcacttatac ttgaaaaacc tcctcctaca
    35341 attggttatt tgacaattga ttttccgaac acaggtagga gtccgattca tgaccaagct
    35401 ggaaaaaatc tagataatct tgcagatgcg gtttatgaag tacttgaaga attaggaatt
    35461 tctgaatata tactttgtgc acatagttgg agtggaattt tagcttgcaa attactcgag
    35521 aaaccaatta agcgtcagac tttagtagca attgaaccga caactaaaaa agtcatgttt
    35581 gctgattttt cagaaaatcc ttatccagaa atggaagagc agatgaggct gattgacgag
    35641 tgtggtcctg aactttattt taagaactta actcaagcaa catttagtcc tgaaacgaat
    35701 aaaaaaatct gggaattaat gcaagaaaaa ggcttagagt tggaaaatca agatccagaa
    35761 tttcagatat ctggagagat tactgaggaa gattttgaga atttgtcgat agaatctcat
    35821 gtccctgtat ttattttttg tcagacttat agagaaaaag agtacagaga atcagaatat
    35881 tggacttcca atactaaact cattttagga gggaatcacc attatttaca atggtcagaa
    35941 tcggaaaaaa ttgcggctat tattcgagaa ttgtcagaat aagatggaaa aaaggagatt
    36001 acaggagaca agatgaacta ctttaatgtt gggaaaatcg ttaatacgca gggattacag
    36061 ggtgagatgc gagtcttgtc tgtgacggat tttgcagaag aacggtttaa aaaaggagct
    36121 gagctggctt tgtttgatga aaaagatcag tttgtccaaa cagtgaccat cgctagccac
    36181 cgtaaacaga agaactttga cattattaaa ttcaaagata tgtaccatat caatactatc
    36241 gaaaagtaca agggatacag tctcaaggtc gctgaggaag atttgaatga cctagacgat
    36301 ggtgaatttt actatcacga gattatcggt ttggaagtct atgagggtga tagcttggtt
    36361 ggaaccatca aggaaatcct gcaaccaggt gctaatgatg tctgggtggt caaacgaaaa
    36421 ggcaaacgtg atttgctttt accttatatc ccaccagtgg ttctcaatgt tgatattcca
    36481 aataaacggg tcgatgtgga aatcttagaa gggttagacg atgaagattg atattttaac
    36541 cctctttcca gagatgtttt ctccactgga gcactcaatc gttggaaagg ctcgagaaaa
    36601 agggctcttg gatatccagt atcataattt tcgagaaaat gctgaaaagg cccgtcatgt
    36661 agatgatgag ccctacggag gcggtcaggg catgttgctc agagcacaac ctattttcga
    36721 ttcctttgat gctattgaaa agaaaaatcc gcgcgttatt ctcctcgatc ctgctggaaa
    36781 gcagtttgat caggcttatg ctgaagattt ggctcaagag gaagagctaa tctttatctg
    36841 tgggcactat gagggttatg atgagcgcat taagaccttg gtaacagatg agatttccct
    36901 aggcgactat gtcctcactg gtggagaatt ggcagctatg accatgattg atgctacagt
    36961 tcgcctgatt ccagaagtga ttggcaagga gtctagccac caagatgata gtttttcttc
    37021 aggtctttta gaatatcctc agtacacacg tccctatgat tatcgaggca tggtcgtgcc
    37081 agatgtattg atgagtggcc accatgaaaa gattcgtcag tggcgattgt acgagagttt
    37141 aaagaaaacc tacgagcgca gaccagattt acttgaacat tatcaactga cagtagaaga
    37201 agaaaaaatg ctggcagaaa tcaaagaaaa caaagaataa aggagaaacc tatgcaagta
    37261 atcaaacgta atggcgaaat tgctgaattt aatccagata agatttacca agccatcttg
    37321 aaggcagccc aaactgttta tgttttgaca gatgatttgc gtcaaaatct tgctcaagtc
    37381 actaagaagg tagttttgga tttacaagaa gccaaggtgg aacgtgcgac tatcagtatg
    37441 attcaatcta tggttgaaca tcgtttattg ggcgcaggtt acattaccat tgcagaacac
    37501 tatatttcct atcgtttaca acgtgacttg gaaagaagtg gttatggaga tcatatcgca
    37561 gttcatttac attttgaaca aattcgctaa gaaaaagagt gggatgaagc aactacatct
    37621 cactctttct taaatctatt tttttgggct gtttggacag ttgaggggac aaatcgcagg
    37681 cgttgaatat cgcttatacg gataatccgg ctcacatttt tggaaaaatt tttcacgata
    37741 atttgctggc cttgctgatc atatttgatg atatcacctg taaagcttgt ctcagacaag
    37801 ataaggtgaa cagcggtttg tttctggata gcctcttcaa tagtggctgt aagggagttg
    37861 gtttcagtct ggtcaggttg gtcatgtcca tttaaaaaat catgtatttt atctagaact
    37921 tgctggaatt tatgtctcat attggcctcc cttcttttat atcaatatta tataaaattt
    37981 tcctaaaatc tacaagattt tacgaataaa ctaatgaaac taaaaaagga gaagaaaatg
    38041 gcagaattta catttgaaat cgaagagcac ttgttgactc tttctgaaaa cgaaaaaggt
    38101 tggaccaagg aaattaaccg tgtgagcttt aatggtgccc ctgcaaagtt tgatattcgt
    38161 gcttggagtc cagaccatac taaaatgggc aaagggatta ctctctcaaa tgaagaattt
    38221 caaacgatgg tggatgcctt taaaggcaac taatactctt cgaaaatctc ttcaaaccgc
    38281 atcagctttg ccttgccgta tgtatggtta ctgacttcgt cagtttcatc tacaacctca
    38341 aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt gctctttgat tttcattgag
    38401 tataagtttt caaaataaaa aaaaggatat tgagtcatga taactcggta tcctttttta
    38461 gttagtaaag taagtctgat ttttaaggcg ttgaagtagg ggacggctaa taaaactaat
    38521 agccagaagt ttgccaaggt ctggaatgat aaagggaaga acccccacaa caagagcttt
    38581 ttcaaatgcc attccagcta ggaaatgcaa gctgagaatc ccgccgacaa agacaagggc
    38641 atcacccaag aggtttgcaa gaaaaatctt aacaacacca ctcttgctgt tggttagaga
    38701 ggaagtaagt ccagagtaaa cgagataaaa ccaaagatag cctgcagtag ggccaactaa
    38761 agcctgaaaa ccagctccac ctcctgcaaa gacaggaaga ccgatagcac ctagaagaag
    38821 atagagtcca gcagaaagta cagcctctct cggtctaaag acagtagcaa tcaagccgat
    38881 tgcaaagttt tgcagagtga agggaacagg tccaattgga agactgattt gtgccaaaac
    38941 agcaatgaga gcagccccaa tagcagggat agcataaacg tgagcttttt tcaaaatagt
    39001 taacctcttt tctaatgtat agtaactatt atactcatat aggagtcgat gtcaaccatt
    39061 ttttaaaaac aaggtaacaa aaactgtaac agccgatttt cgtgactagt caagttggat
    39121 aattttttgt tgattcgaaa atcattaaaa aagaagcaga catatttata tcagcttctt
    39181 ttgtttcgat taacgcatgg ttacaaattc ttcagatgaa gttgggtgaa tcgctacagt
    39241 tgcgtcaaag tcagccttgg ttgctcccat tttgatagca acggcaaatc cctgaatcat
    39301 ttcatcaacg ccgtagccaa ttccatgaag tccgacaact ttttcttctg aaccagctgt
    39361 tatgagtttg aaacgggatt cttgacggtt gcgagtgcaa gcagagtaca tagatgcaaa
    39421 gcttgatttg taaaccttga tttggtcttg accgtattct ttaatagctt gctcttctgt
    39481 caaaccaaca gttccgatag cagggtgtga aaagacaaca gttggaatag ttgagtaatc
    39541 catttttgca gtagtttttc cgttaaagag acgttcagat agggtacgtc cggccttgat
    39601 tgcaactgga gtcagttctt tctcgcccgt tacatcacct agagcataga ttccctcaac
    39661 aacagtattt tggtattcat ccacttggat aaagccacgt tcgttcagag tcactccagc
    39721 tttttcaagt tgcaagccct taacgtttgg acggcggcct gtagcccaga taacttggct
    39781 agctgtgtga ctagtaccat cttcgaaatg aatggtaatg ccgtcagtag ttttttctaa
    39841 cttgacaggg actttgtgag tgtgaagtgg taagtttgtt ctttccattt ccttgaccaa
    39901 accttcaacg atgtaggaat caaaaccacg taaaggacga tcgcggcgaa caaagagatc
    39961 tgtcttgaca ccaaaagtgt ggagtacgcc agctaattca acggcgatat aaccagcgcc
    40021 tagaatggca actgactctg gaagttcttc ccaggcaaat acatcatcag aagagccacc
    40081 tagctcagca ccaggaatat taggaatact tggatgggca cctgtagcaa tcacgatatg
    40141 tttagcacga atcagttcac catttacgct tacagtatga gaatctacaa attcagcatg
    40201 accttcaatc aagtctacac cgttgcgttt aaaactacca tcataagaag aacgagcgcg
    40261 atcaatgtag gcttcacgat tgcgacgtag ggttgcaaag ttaaagttaa gatcagtagt
    40321 cttaaagccg tagtcttctc caaattgatg gaaagtctca gcgatttgcg ccccgtacca
    40381 catgattttt ttaggaacac aaccgacgtt gacacaggtt ccacctaatt tcttttcctc
    40441 aataacggct gctttggctc catgttcacc agcacggttc atggtagcga ttcctccgct
    40501 acctccaccg atagcaatga tatcatattc tctcattgaa aactcctttg taatctttta
    40561 aatagtagag tgtctttttt gatagttata ttttattctt tttttgattt gattgcaaaa
    40621 atctgctacg cacaaaaaat tgcaaaaaag cttgccaaat aagtcaagat agtgtattat
    40681 atatctagta caatagaaaa gcaaaattcc gaacgattgt ttaatcctga actgccatta
    40741 tttccatctg aactgcattg tttgctggag ggaaatttgg tataatagca aagtattgta
    40801 aaaaagaaaa ggagtttcat tatgaagaaa aagaatggta aagctaaaaa gtggcaactg
    40861 tatgcagcaa tcggtgctgc gagtgtagtt gtattgggtg ccggggggat tttactcttt
    40921 agacaacctt ctcagactgc tctaaaagat gagcctactc atcttgttgt tgccaatgaa
    40981 ggaagcgtgg catcctctgt tttattgtca gggacagtaa cagcaaaaaa tgaacaatat
    41041 gtttattttg atgctagtaa gggtgattta gatgaaatcc ttgtttctgt gggcgataag
    41101 gtcagcgaag ggcaggcttt agtcaagtac agtagttcag aagcgcaggc ggcctatgat
    41161 tcagctagtc gagcagtagc taaggcagat cgtcatatca atgaactcaa tcaagcacga
    41221 aatgaagccg cttcagctca ggctccacag ttaccagcgc cagtaggagg agaagatgca
    41281 acggtgcaaa gcccaactcc agtggctgga aattctgttg cttctattga tgctcaattg
    41341 ggtgatgccc gtgatgcgcg tgcagatgct gcagcgcaat taagcaaggc tcaaagtcaa
    41401 ttggatgcaa caactgttct cagtacccta gagggaactg tagtcgaagt caatagcaat
    41461 gtttctaaat ctccaacagg ggcgagtcaa gttatggttc atattgtcag caatgaaaat
    41521 ttacaagtca agggagaatt gtctgagtac aatctagcca acctttctgt aggtcaagaa
    41581 gtaagcttta cttctaaagt gtatcctgat aaaaaatgga ctgggaaatt aagctatatt
    41641 tctgactatc ctaaaaacaa tggtgaagca gctagtccag cagccgggaa taatacaggt
    41701 tctaaatacc cttatactat tgatgtgaca ggcgaggttg gtgatttgaa acaaggtttt
    41761 tctgtcaaca ttgaggttaa aagcaaaact aaggctattc ttgttcctgt tagcagtcta
    41821 gtaatggatg atagtaaaaa ttatgtctgg attgtggatg aacaacaaaa ggctaaaaaa
    41881 gttgaggttt cattgggaaa tgctgacgca gaaaatcaag aaatcacttc tggtttaacg
    41941 aacggtgcta aggtcatcag taatccaaca tcttccttgg aagaaggaaa agaggtgaag
    42001 gctgatgaag caactaatta gtctaaaaaa tatcttcaga agttaccgta atggtgacca
    42061 agaactgcag gttctcaaaa atatcaatct agaagtgaat gagggtgaat ttgtagccat
    42121 catgggacca tctgggtctg gtaagtccac tctgatgaat acgattggca tgttggatac
    42181 accaaccagt ggagaatatt atcttgaagg tcaagaagtg gctgggcttg gtgaaaaaca
    42241 actagctaag gtccgtaacc aacaaatcgg ttttgtcttt cagcagttct ttcttctatc
    42301 gaagctcaat gctctgcaaa atgtagaatt gcccttgatt tacgcaggag tttcgtcttc
    42361 aaaacgtcgc aagttggctg aggaatattt agacaaggtt gaattgacag aacgtagtca
    42421 ccatttacct tcagaattat ctggtggtca aaagcaacgt gtagccattg cgcgtgcctt
    42481 ggtaaacaat ccttctatta tcctagcgga tgaaccgaca ggagccttgg ataccaaaac
    42541 aggtaaccaa attatgcaat tattggttga tttgaataaa gaaggaaaaa ccattatcat
    42601 ggtaacgcat gagcctgaga ttgctgccta tgccaaacgt cagattgtca ttcgggatgg
    42661 ggtcatttcg tctgacagtg ctcagttagg aaaggaggaa aactaagatg cagaatctga
    42721 aatttgcctt ttcatctatc atggctcaca agatgcgttc tttgcttact atgattggga
    42781 ttattatcgg tgtttcatca gttgttgtga ttatggcttt gggtgattcc ctatctcgtc
    42841 aagtcaataa agatatgact aaatctcaga aaaatattag cgtctttttc tctcctaaaa
    42901 aaagtaaaga tgggtctttt actcagaaac aatcagcttt tacggtttct ggaaaggaag
    42961 aggaagttcc tgttgaaccg ccaaaaccgc aagaatcctg ggtccaagag gcagctaaac
    43021 tgaagggagt ggatagttac tatgtaacca attcaacgaa tgccatcttg acctatcaag
    43081 ataaaaaggt tgagaatgct aatttgacag gtggaaacag aacttacatg gacgctgtta
    43141 agaatgaaat tattgcaggt cgtagtctga gagagcaaga tttcaaagag tttgcaagtg
    43201 tcattttgct agatgaggaa ttgtccatta gtttatttga atctcctcaa gaggctatta
    43261 acaaggttgt agaagtcaat ggatttagtt accgggtcat tggggtttat actagtccgg
    43321 aggctaaaag atcaaaaata tatgggtttg gtggcttgcc tattactacc aatatctccc
    43381 ttgctgcgaa ttttaatgta gatgaaatag ctaatattgt ctttcgagtg aatgatacca
    43441 gtttaacccc aactctgggt ccagaactgg cacgaaaaat gacagagctt gcaggcttac
    43501 aacagggaga ataccaggtg gcagatgagt ccgttgtatt tgcagaaatt caacaatcgt
    43561 ttagttttat gacgacgatt attagttcca tcgcagggat ttctctcttt gttggaggaa
    43621 ctggtgtcat gaacatcatg ctggtttcgg tgacagagcg cactcgtgag attggtcttc
    43681 gtaaggcttt gggtgcaaca cgtgccaata ttttaattca gtttttgatt gaatccatga
    43741 ttttgacctt gttaggtggc ttaattggct tgacaattgc aagtggttta actgccttag
    43801 caggtttgtt actgcaaggt ttaatagaag gtatagaagt tggagtatca atcccagttg
    43861 ccctatttag tcttgcagtt tcggctagtg ttggtatgat ttttggagtc ttgccagcca
    43921 acaaggcatc gaaacttgat ccaattgaag cccttcgtta tgaatgagat caacaagatg
    43981 gacactcgtc tatcttgttt ttgtatggat ttccctatcg aaattcatta aaaatgtgat
    44041 ataatgaagt gttagaaaaa caggtttcat ttgcctggaa aggaaaaatt atgtctgaaa
    44101 aaaattttta tattacaacg ccgatttact atccatctgg gaaacttcat atcggttctg
    44161 cctacacaac tatcgcatgt gatgtcctag cacgttacaa acgcctgatg ggctacgatg
    44221 tattttatct gacaggtctt gatgaacatg gtcagaaaat ccagcagaaa gcggaagaag
    44281 ctggtattac acctcaagcc tatgttgatg gaatggcggt tggagttaaa gaactctggc
    44341 aattactaga tatctcatac gataaattta tccgtacaac tgatgactac catgaaaaag
    44401 ttgtcgcaca ggtctttgaa cgcttacttg ctcaagatga tatttacttg ggtgaatact
    44461 ctggttggta ttcagtatca gacgaagaat tctttacaga aagccagctg gcagaagttt
    44521 tccgtgatga agctggaaat gtgactggtg gtattgctcc atcaggtcat gaggttgaat
    44581 gggtttctga agaatcatac tttcttcgcc ttagcaaata ccaagaccgt ttggtcgaat
    44641 ttttcaaagc tcatcctgaa tttatcacgc cagatggtcg ccttaatgaa atgctacgca
    44701 acttcatcga gccaggtttg gaagatttgg cggtatctcg tacaaccttt acatggggag
    44761 tgcctgtccc atcaaatcca aaacacgttg tctacgtttg gattgatgcc cttcttaact
    44821 atgcgacagc tcttggctac gctcaagacg aacatggtaa ctttgacaag ttctggaatg
    44881 gaacagtctt ccatatggta ggaaaagata tccttcgctt ccactctatc tactggccaa
    44941 tccttcttat gatgttggat gttaaattac ctgatcgttt gattgcccat ggttggtttg
    45001 tcatgaaaga cggaaaaatg tctaagtcaa aagggaatgt cgtttaccct gaaatgttgg
    45061 tagagcgtta tggactagat ccacttcgtt actacctcat gcgtaacctt ccagttggtt
    45121 cagacggaac ctttactcct gaagactatg ttggccgtat caactatgaa ttggctaatg
    45181 accttgggaa cctccttaac cgtacggttt ccatgattaa taagtacttt gatggacaaa
    45241 tccctgccta tgtagaaggt gtgactgaat ttgatcatgt tcttgctgag gttgcagaac
    45301 aatcaatcgc agacttccat acacacatgg aagcagttga ctatccacgt gcgcttgaag
    45361 cagtctggac tctgatctct cgtaccaata aatacatcga tgagaccgca ccatgggtct
    45421 tggccaagga tgaagctctt cgtgaccaat tggcaagtgt catgagccac ttggcagcca
    45481 gcattcgtgt agttgctcac ttgattgaac catttatgat ggaaactagt cgtgcagttt
    45541 tgactcaact tggtttggaa gaagtttcta gtcttgaaaa cttgagtttg gctgacttcc
    45601 cagcagatgt gactgtagtt gccaaaggaa cacctatctt tccacgtcta aatatggaag
    45661 aagaaatcgc ctatatcaag gaacaaatgg aaggcaataa accagcagtc gaaaaagaat
    45721 ggaatccgga cgaagttgag ctcaaactaa acaaggatga aatcaagttt gaagactttg
    45781 acaaggttga aatccgtgtg gcagaagtca aagaagtgtc taaagtagaa ggttcagata
    45841 agttgcttca attctgcttg gatgctggtg atggagaaga tcgtcagatt ctttcaggaa
    45901 ttgccaaata ctatccaaat gaacaagaat tggtcggcaa gaaagttcaa atcgttgcta
    45961 acctcaaacc acgtaaaatg atgaaaaaat atgtcagcca gggtatgatt ctctcagctg
    46021 aacatgatgg caaattaacc cttctcacag ttgatccagc tgtaccaaat ggaagtgtga
    46081 ttgggtaaaa gtagacagga ctagttcagg ctagttctgt ttttttattt atactcaatg
    46141 aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaaacacag ttttgaggtt
    46201 gtagataaga ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac
    46261 gaagtcagta atcatatcta cggcaaggcg acactgacga agtttgaatt ggattttcgc
    46321 agagtgtaaa ttgttgaaac taggttgtca taccatgtat accacttggg ctttggtagt
    46381 agctaactgc actaaatata atataaggag gtttttatgg ggaaaggcca ttggaatcgg
    46441 aaaagagttt atagcattcg taagtttgct gtgggagctt gctcagtaat gattgggact
    46501 tgtgcagttc tattaggagg aaatatagct ggagaatctg tagtttatgc ggatgaaaca
    46561 cttattactc atactgctga gaaacctaaa gaggaaaaaa tgatagtaga agaaaaggct
    46621 gataaagctt tggaaactaa aaatgtagtt gaaaggacag aacaaagtga acctagttca
    46681 actgaggcta ttgcatctga gaagaaagaa gatgaagccg taactccaaa agaggaaaaa
    46741 gtgtctgcta aactggaaga aaaagctcca aggatagaat cacaagcttc aagtcaagaa
    46801 aaaccgctca aggaagatgc taaagctgta acaaatgaag aaatgaatca aatgattgaa
    46861 gacaggaaag tggattttaa tcaaaattgg tactttaaac tcaatgcaaa ttctaaggaa
    46921 gcccttaaac ctgatgcaga cgtatctacg tggaaaaaat tagatttacc gtatgactgg
    46981 agtatcttta acgatttcga tcatgaatct cctgcacaaa atgaaggtgg acagctcaac
    47041 ggtggggaag cttggtatcg caagactttc aaactagatg aaaaagacct caagaaaaat
    47101 gttcgcctta cttttgatgg cgtctacatg gattctcaag tttatgtcaa tggtcagtta
    47161 gtggggcatt atccaaatgg ttataaccag ttctcatatg atatcaccaa ataccttcaa
    47221 aaagatggtc gtgagaatgt gattgctgtc catgcagtca acaaacagcc aagtagccgt
    47281 tggtattcag gaagtggtat ctatcgtgat gtgactttac aagtgacaga taaggtgcat
    47341 gttgagaaaa atgggacaac tattttaaca ccaaaacttg aagaacaaca acatggcaag
    47401 gttgaaactc atgtgaccag caaaatcatc aatacggacg acaaagacca tgaacttgta
    47461 gccgaatatc aaatcgttga acgaggtggt catgctgtaa caggcttagt tcgtacagcg
    47521 agtcgtacct taaaagcaca tgaatcaaca agcctagatg cgattttaga agttgaaaga
    47581 ccaaaactct ggaccgtttt aaatgacaaa cctgccttgt acgaattgat tacgcgtgtt
    47641 taccgtgacg gtcaattggt tgatgctaag aaggatttgt ttggttaccg ttactatcac
    47701 tggactccaa atgaaggttt ctctttgaat ggtgaacgta ttaaattcca tggagtatcc
    47761 ttgcaccacg accatggggc gcttggagca gaagaaaact ataaagcaga atatcgccgt
    47821 ctcaaacaaa tgaaggagat gggagttaac tccatccgta caacccacaa ccctgctagt
    47881 gagcaaacct tgcaaatcgc agcagaacta ggtttactcg ttcaggaaga ggcttttgat
    47941 acttggtatg gtggcaagaa accttatgac tatggacgtt tttttgaaaa agatgccact
    48001 cacccagaag ctcgaaaagg tgaaaaatgg tctgattttg acctacgtac catggtcgaa
    48061 agaggcaaaa acaaccctgc tatcttcatg tggtcaattg gtaatgaaat aggtgaagct
    48121 aatggtgatg cccactcttt agcaactgtt aaacgtttgg tcaaggttat caaggatgtt
    48181 gataagactc gctatgttac catgggagca gataaattcc gtttcggtaa tggtagcgga
    48241 gggcatgaga aaattgctga tgaactcgat gctgttggat ttaactattc tgaagataat
    48301 tacaaagccc ttagagctaa gcatccaaaa tggttgattt atggatcaga aacatcttca
    48361 gctacccgta cacgtggaag ttactatcgc cctgaacgtg aattgaaaca tagcaatgga
    48421 cctgagcgta attatgaaca gtctgactat gggaatgatc gtgtgggttg ggggaaaaca
    48481 gcaaccgctt catggacttt tgaccgtgac aacgctggct atgctggaca gtttatctgg
    48541 acaggtacgg actatattgg tgaacctaca ccatggcaca accaaaatca aactcctgtt
    48601 aagagctctt actttggtat cgtagataca gccggcattc caaaacatga cttctatctc
    48661 taccaaagcc aatgggtttc tgttaagaag aaaccgatgg tacaccttct tcctcactgg
    48721 aactgggaaa acaaagaatt agcatccaaa gtagctgact cagaaggtaa gattccagtt
    48781 cgtgcttatt cgaatgcttc tagtgtagaa ttgttcttga atggaaaatc tcttggtctt
    48841 aagactttca ataaaaaaca aaccagcgat gggcggactt accaagaagg tgcaaatgct
    48901 aatgaacttt atcttgaatg gaaagttgcc tatcaaccag gtaccttgga agcaattgct
    48961 cgtgatgaat ctggcaagga aattgctcga gataagatta cgactgctgg taagccagcg
    49021 gcagttcgtc ttattaagga agaccatgcg attgcagcag atggaaaaga cttgacttac
    49081 atctactatg aaattgttga cagccagggg aatgtggttc caactgctaa taatctggtt
    49141 cgcttccaat tgcatggcca aggtcaactg gtcggtgtag ataacggaga acaagccagc
    49201 cgtgaacgct ataaggcgca agcagatggt tcttggattc gtaaagcatt taatggtaaa
    49261 ggtgttgcca ttgtcaaatc aactgaacaa gcagggaaat tcacccttac tgcccactct
    49321 gatctcttga aatcgaacca agtcactgtc tttactggta agaaagaagg acaagaaaag
    49381 actgttttgg ggacagaggt gccaaaagta cagaccatta ttggagaggc acctgaaatg
    49441 cctaccactg ttccgtttgt atacagtgat ggtagccgtg cagaacgtcc tgtaacctgg
    49501 tcttcagtag atgtgagcaa gcctggtatt gtaacggtga aaggtatggc tgacggacga
    49561 gaagtagaag ctcgtgtaga agtgattgct cttaaatcag agctaccagt tgtgaaacgt
    49621 attgctccaa atactgactt gaattctgta gacaaatctg tttcctatgt tttgactgat
    49681 ggaagtgtac aagagtacga agtagatagc tgggagattg ccgaagaaga taaagctaag
    49741 ttagcaattc caggttctcg tattcaagcg accggttatt tagaaggtca accaattcat
    49801 gcaacccttg tggtagaaga aggcaatcct gcagcacctg tagtgccaac tgttactgtt
    49861 ggaggtgaag cagtaacagg tcttactagt cgacaaccaa tgcaatatcg tactctatct
    49921 tatggtgccc aattgccaga agtcacagca agtgctgaaa atgctgatgt gacagttctt
    49981 caagcaagcg cagcaaacgg catgcgtgcg atcatcttta ttcagcctaa agatggtggc
    50041 cctcttcaaa cctatgcaat tcaattcctt gaagaagcgc caaaaattgc tcacttgagc
    50101 ttgcaagtgg aaaaagctga cagtctcaaa gaagaccaaa ctgtcaaatt gtcggttcga
    50161 gctcactatc aagatggaac gcaagctgta ttaccagctg ataaagtaac cttctctaca
    50221 agtggtgaag gggaagtcgc aattcgtaaa ggaatgcttg agttgcataa gccaggagca
    50281 gtcactctca aagcggaata tgagggagct acaggtcaaa tcactctcac tatccaagcc
    50341 aatactgaga agaagattgc gcaatctatc cgtcctgtaa atgtagtcac agatttgcat
    50401 caaaaaccta ctcttccaac aacagtaacg gttgagtatg acaaaggttt ccctaaagct
    50461 cacaaagtca cttggcaagc tattccgaaa gaaaaactag actcttatca aacatttgaa
    50521 gtactaggta aagttgaagg aattgacctt gaagcgcgtg caaaagtctc tgtagaaggt
    50581 atcgtttcag ttgaagaagt cagtgtgaca actccaatcg cagaagcacc acaattacca
    50641 gaaagcgttc ggacatatga ttcaaatggt cacgtttcat cagctaaggt tgcatgggat
    50701 gcgattcgta tagagcaata cgctaaggaa ggtgtcttta cagttaatgg tcgcttagaa
    50761 ggtactcaat taacaactaa acttcatgtt cgcgtatctg ctcaaactga gcaaggtgca
    50821 aacatttctg accaatggac cggttcagaa ttgccacttg cctttgcttc agattcaaat
    50881 ccaagcgacc cagtttcaaa tgttaatgac aagctcattt cctacaataa ccaaccagcc
    50941 aatcgttgga caaactggaa tcgtagtaat ccagaagctt cagtcggtgt tctgtttgga
    51001 gattcaggta tcttgagcaa acgctccgtt gataatctaa gtgtcggatt ccacgaagac
    51061 catggagttg gtgcaccgaa gtcttatgtg attgagtatt atgttggtaa gactgtccca
    51121 acagctccta aaaaccctag ttttgttggt aatgaggacc atgtctttaa tgattctgcc
    51181 aactggaaac cagttactaa tctaaaagcc cctgctcaac tcaaggctgg agaaatgaac
    51241 cactttagct ttgataaagt tgaaacctat gctattcgta ttcgcatggt taaagcagat
    51301 aacaagcgtg gaacgtctat cacagaggta caaatctttg cgaaacaagt tgcggcagcc
    51361 aaacaaggac aaacaagaat ccaagttgac ggcaaagact tagcaaactt caaccctgat
    51421 ttgacagact actaccttga gtctgtagat ggaaaagttc cggcagtcac agcaaatgtt
    51481 agcaacaatg gtctcgctac cgtcgttcca agcgttcgtg aaggtgagcc agttcgtgtc
    51541 atcgcgaaag ctgaaaatgg cgacatctta ggagaatacc gtctgcactt cactaaggat
    51601 aagaacttac tttctcataa accagttgct gcggttaaac aagctcgctt gctacaagta
    51661 ggtcaagcac ttgaattgcc gactaaggtt ccagtttact tcacaggtaa agacggctac
    51721 gaaacaaaag atttgtcagt tgaatgggaa gaagttccag cagaaaatct gacaaaagca
    51781 ggtcaattta ccgttcgagg ccatgtcctt ggtagtgatc ttgttgctga ggtcactgta
    51841 cgagtgacag acaaactagg cgaagctctt tcagataacc ctaactatga tgaaaacagt
    51901 aaccaggcct ttgcttcagc aaccaatgat attgacaaaa actctcatga ccgcgttgac
    51961 tatctcaatg acggagatca ttcagaaaat cgtcgttgga caaactggtc tccaacacca
    52021 tcttctaatc cagaagtatc agcgggtgtg atcttccgtg aaaatggtaa gattgtagaa
    52081 cggactgttg cgcaagccaa acttcacttc tttgcagata gtggtacgga tgcaccaact
    52141 aaactcgttt tagaacgcta tgtcggtcca gagtttgaag tgccaaccta ctattcaaac
    52201 taccaagcct acgacgcaga ccatccattc aacaatccag aaaattggga agctgtgcct
    52261 tatcgtgcgg ataaagacat cgcagctggt gatgaaatca acgtaacatt taaagctgtc
    52321 aaagccaaag ctatgagatg gcgtatggag cgtaaagcag ataagagcgg tgttgcgatg
    52381 attgagatga ccttccttgc accaagtgaa ttgcctcaag aaagcacgca atcgaagatt
    52441 cttgtagatg gaaaagaact tgctgatttc gctgaaaatc gtcaagacta tcaaattacc
    52501 tataaaggtc aacggccaaa agtctcagtt gaagaaaaca atcaagtagc ttcaactgtg
    52561 gtagatagtg gagaagatag ccttccagta cttgttcgcc tcgtttcaga aagtggaaaa
    52621 caagtcaagg aataccgtat ccacttgact aaggaaaaac cagtttctga gaagacagtt
    52681 gctgctgtac aagaagatct tccaaaactc gaatttgttg aaaaagattt ggcctacaag
    52741 acagttgaga aaaaagattc aacactgtat ctaggtgaaa ctcgtgtaga acaagaagga
    52801 aaaactggta aagaacgtat ctttacagcg attaatcctg atggaagtaa ggaagaaaaa
    52861 ctccgtgaag tggtagaagc tccgacagac cgcatcgtct tggttggaac caaaccagta
    52921 gctcaagaag ctaaaaaacc acaagtgtca gaaaaagcag atacaaaacc aattgattca
    52981 agtgaagcta gtcaaactaa taaagcccag ttaccaaata caggtagtgc gtcaagccaa
    53041 gcagcagtag cagcaggttt agctcttcta ggtttgagtg caggattagt agttactaaa
    53101 ggtaaaaaag aagactagaa attttgatac cttctttatc attaaagacc aaagaaaaac
    53161 tcttgtccta aatagaagat aaagagtctg gaacaaaata gttctcaacc acaaaaaagc
    53221 tagatatttc caattgtgga actctagctt tttaattttg agtcattctc ttattgtata
    53281 gtggattgaa actagaatag tacacttcta cttctaaaac attgttagaa atcgatttga
    53341 ctgtccttat cgatttgtcc tgttcttatt tcattttact atattttagg aggttattgg
    53401 ccataagtac caatcccatg tcaattctca cttgcccctc agattacatc tcttgtaacc
    53461 caaagaagcc tttatctgcc caaagacagg ttccacatca atcttgcgtt gagcgaaaat
    53521 ctgtctacct tggggagata aaagcgcctg acattcttta gctttcaagt tttgatagcg
    53581 ttcgttcata tatagtccct tttgaggggc tgattcaggt tcgtcggcgt agtaaacctt
    53641 gatttcctgt tgaaagtctg tctgtgtttt ctgatgtttg gtatggtgaa aacgataata
    53701 ccagccatca ggatgtgtgt agctatcctc cttgtcatta tagtgccaat tcgctaagtt
    53761 tttagctgac tctttatacc ctctcttttg tttcttatca aacatggcat atttaatcag
    53821 gaggggagtg atttcttctt gaaaatagac ttgtatctgt tcttgaagtt tggcggagaa
    53881 tttctctgtc gttttcttcc acacaaaact atacttgttg gcattggctt caatcttagt
    53941 tccgtcaata aacaaacaat ctaaggtcac taactcttcc atttttcaat ttttcgacca
    54001 gagaaaatcc cttgtgaata ggcaaataga agagtagata caagcatttt aaggtgataa
    54061 gacaggcgat caaaggcatg atagaaggcg tggaaatgac aatcctccaa ggtattcacc
    54121 actttttcaa tagtaaaaac gagatggtct tgtggcaaga aggaactgat ttctagtggt
    54181 aaagttgttt gatttgtgtt atagtgaata tgcatgggat agcctttcta aatggtttat
    54241 tgggcaattc tattttacca agactatcgt aaccatgcaa aaaaagcaac ggcaaatccg
    54301 ttgctttttt tggagataag agactattgt cccagactct tttctttgta taaaattgta
    54361 tagtgttatt gtctatacta ttttgtagag aaagaaaaaa tccctagaaa atgcttaggg
    54421 attcgactat ttcattaaga acaattcaac aatcatttct acatacatga taagggttaa
    54481 taagaatcct gcacgccaga agaatttgat gaatttagga tagtaaaagc tgcgtttttt
    54541 caaaaggaag aaaaagacga gaataatggc taggatcgag agggctagcc ccagtctagg
    54601 gaggaaatta tgggtaaagg ttttagctgt aatcaggtaa tattcaaata ccaagaccgg
    54661 aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat ctaaaaagtt tggttaggat
    54721 aatgcagacg actaaggtca gtatcaataa taaaatagat gctaatttca ttaaaatcat
    54781 acccatattg tatcataaaa aaaggctaat ggaaacgaga aacagaggaa tttataggaa
    54841 agtcaggctt ttgagattgt gggtgatttt tgttataatg aaagtcatga aatcttataa
    54901 taccttgaat gattattatc gaaaattctt tggagaaaag acttttaaag tccctattga
    54961 tgcgggattt gactgtccca atcgtgatgg aactgtggct catggaggct gtactttttg
    55021 tacggtttca ggttctggag atgctattgt agccccagat gcgcctatcc gtgagcaatt
    55081 ttataaggaa attgacttta tgcaccgtaa gtggccggat gttcagaagt atctggttta
    55141 ttttcaaaat tttaccaaca cccatgaaaa ggtggaagtt attcgagagc gttatgaaca
    55201 ggctatcaat gagccaggtg tggtaggtat caatattgga acgcgcccag actgtttacc
    55261 agacgaaacc atcgaatatt tggctgagtt atcggagtgc atgcatgtga cggttgaatt
    55321 gggcttgcag accacttatg aagcaacctc tgacctgatt aaccgtgtgc attcttatga
    55381 attgtaggtg gaaacggtca agcgtttgag aaagtatccc aagattgaga ttgtttccca
    55441 tttgatcaat ggcttgcctg gtgaaaccca tgagatgatg gttgaaaatg tccgccgttg
    55501 tgtcacggat aacgatattc aagggattaa actgcatttg ctccatctta tgacaaatac
    55561 tcgtatgcaa cgagattacc atgagggacg tttacaattg atgagtcagg acgaatatgt
    55621 cagggtcatc tgtgaccaac tggaaattat tcccaaacat atcgtcatcc atcgaattac
    55681 aggagatgcg cctagggata tgctgattgg tcctatgtgg agcctcaaaa aatgggaagt
    55741 cctcaacagc attgagatgg agatgcgacg tcgtggaagt gttcaaggat gcaaggctgt
    55801 aaaacaggag tttgaaaatg aaaagaccac ttgagatggc acatgatttt ttggctgagg
    55861 tcgtgacaaa agaggatgtc gtagtggatg cgactatggg aaatggtcat gacacgcttt
    55921 ttttagccaa gctagccaag caagtctatg cctttgatat tcagaagcaa gccttggaaa
    55981 agacccaaga gcgtttgcat caggctggct tgacaaatgc ccagttaatc ttgcaaggcc
    56041 atgagacact ggaccagttt gtgacaaaag ctaaggcagg gatttttaat ctgggctatt
    56101 tgccgtcagc tgataagtct gtcatcaccc gaccgcagac aacgattgag gcattagaaa
    56161 agctatgtgg cttacttgtc aaaggtggac gaattgctat tatgatttac tatggtcatg
    56221 aaggaggcga cctcgagaga gatgctgtct tggattttgt gatccagttg aaccaacaag
    56281 agtacacagc tgccatttac cgaactttaa accaagtcaa caacccgccg tttttagtga
    56341 tgattgaaaa attagagaga tacagacatg gataaacaat acctacacga aaagctggat
    56401 gccatgcgcc agaattttgt tgaatcaact caccacgaac gagcggtggg cgtgctagac
    56461 caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa aattagttgc tcttgaaatg
    56521 gaacggtgcc agagaaaaat tgagcacaaa gactgttcca agattgacca aaaaatcaaa
    56581 gagcagaagg agatatttga atcctgttgt aaaaaagatt aaggaggacg tgcgtggaat
    56641 tactgattta cctcatccta tttttactgg ttttgattgt ctcaagtaca accaataagc
    56701 tcctaccctt tttgcctctc cctttggtgc agattctttt gggaattgtg attggtctct
    56761 ttttacccaa tactgacttt catcttaata cggagttgtt tttggccctg gttatcggac
    56821 ccttgctttt ccgagaggct gaagaagcag atgttacggc tattttaaaa cactggcgaa
    56881 tcattgttta tctcatattt ccagtgattt ttatctcgac cctgagtttg ggtggcttgg
    56941 cccatcttat ttggttcagc cttcccttgg cagcttgctt ggctgttggg gcagcccttg
    57001 gtcctacgga cttggtggcc tttgcctctc tttcggagcg ttttagcttt cctaagcgcg
    57061 tgtccaatat tcttaagggc gaaggactct tgaatgatgc ttctggtttg gtggcttttc
    57121 aggtagcttt gacagcttgg acaactggag ctttttctct ggggcaagct agcagttcgc
    57181 tcatcttttc aatcctaggc ggttttttaa ttggcttttt aacagccatg accaatcgtt
    57241 tcctccatag cttcttgcta agtgtgagag caacggatat tgctagtgag ctccttctgg
    57301 aattgagttt gcccttggta accttcttcc tggcagaaga agtccatgtt tcagggatta
    57361 ttgccgtcgt agttgctgga attttaaagg caagtcgctt caagaaaatc acgctcctcg
    57421 aagcccaagt ggatacggtg accgagacgg tctggcatac agtgaccttt atgctcaacg
    57481 gttctgtctt tgtgatttta gggatggagt tggaaatgat agcagaacct atcttgacca
    57541 atccaatcta taatcctcta cttttattgc tatctctcat cgcccttacc tttgtcctct
    57601 ttgtcattcg ttttattatg atctatggct attatgccta tagaacccga cgcctcaaga
    57661 aaaagctaaa taagtatatg aaggacatgt ttctcttgac cttttcaggt gttaagggaa
    57721 cggtgtcgat tgctacgatt ctcttgatac caagtaatct agaacaggag tatcctctct
    57781 tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt aacaggtctc ttggtcttgc
    57841 ctcatctttc tgatgaagag gaagaaagca aggattatct catgcatatc gccattttga
    57901 atgaagtaac gctagagttg gaaaaagagt tggaagacac tagaaataaa cttcccctct
    57961 atgcggctat tgacaattat catggacgta ttgaaaatct cattttaagc caagaaaacc
    58021 aggatgatca agaagactgg gctgctttga aactcttgat tcttagtatt gaaagtgatg
    58081 gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg tgcttaccga gtttaccaac
    58141 gttatctgaa aaatatagaa caaggaatca atcgtaaact tccctcaaga ctgacctatt
    58201 attttcttgt ttccttgagg attttacgtt ttctccttca tgaagttttt actctcggaa
    58261 agaccttccg tagctggaag aacaaggagc aaagccgtct ccgtgctctt gattatgacc
    58321 aaattgcaga gctctatctt gccaatacag agatgattat tgaaagtttg gaaaacctga
    58381 agggagtcta cagacgctct ttgattagtt ttatgcagga gtctcgtctt cgagaaacag
    58441 ctattatcag cagtggtgcc tttgtcgaac gggttatcaa tcgtgtcaaa cccaacaata
    58501 tcgatgaaat gctgagaggc tattatctgg agcgcaagtt gattttcgaa tacgaagaaa
    58561 aacgattgat tacgactaag tatgccaaga aattacgaca aaatgtaaat aacttagaga
    58621 actattcctt gaaggaagct gccaataccc taccgtatga tatggtggaa ttggtaagaa
    58681 gaaattagtt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    58741 gtatgtgact gacttcgtca gtcttatcta caacctcaaa acagtgtttt gagcagcttg
    58801 cggctagctt tctagtttgc tctttgattt tcattgagta taagattata agtgaaggag
    58861 tatgatatga catgaaaaag tggtggaaag agctgataga caaaccttta ttaaaagctt
    58921 ttttgcatta ttatcaagca tcagatagtg agttgaccag tgtcgcagta gcctactatt
    58981 ggttgatttc gattttcccc ctgcttttgg tggtggtcaa tatcctcccc tattttcaga
    59041 ttcctgtggg agaatttttg ggctttatga aagacgttct gcccccaagc ctctatgaag
    59101 gtgtggaaaa aatagccaga gaagttttga cgcaaccttc aacaggttta ttgagttttt
    59161 ctgttttatc ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa aaagctttta
    59221 acaaggctta tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg ctgagtctcc
    59281 tagtcagttt tggcttgcag ctcctctttg cgtttgcctt gtttttgatc ttatttggtc
    59341 agatgatttt ggctttactt gctcattatt ggacaaaaga tggcattatc tatcaggctt
    59401 tacaagggtt ggcaggtcct ctgatttacg ccctcctctt tgctatcttg gtcatgcttt
    59461 attattttct tcccaatcta tctaacagga aaattagcta taccctacca ggcagtgcct
    59521 ttgttctctt agtgatttta ggtttactaa ctctgttctc tagttatctc aattactatg
    59581 tccatcattt ggtggatgtc cgaattttag gttccgttct tcttgttgtt atgatgtttt
    59641 ggtttatctt gattgctaaa attgttatcc taggcgcggt tatcaatgcc agtatgcaga
    59701 gtttgaaaga tccggtcttt aaaaaagact aactatttat ctattataaa agcgcatagt
    59761 atcaagactt tatagaacct tgatactatg cgcttttgtg ctttgacagt tttttgtata
    59821 gtttttgtcc aagatttcta aatcatctga ttaaattcct attttcccct atcattgtcc
    59881 ctgttttttc gaaaatggaa ggagtataat aaatctatca ataaaatgat aggaggaact
    59941 ttatgggtca tattttcttt tttctaagtg tctttttggc agggattcta tccttctttt
    60001 ctccttgtat cttacctttg ttaccggtct atacaggggt gttactagat gataaggatg
    60061 gtgctcaggc ttctagcggc aaattttcaa tctcagttac tagtttatta cgaactctgg
    60121 cctttatagc aggaatttcc tttatattta ttttgttggg ctatggagct ggttttttag
    60181 gcgatttgct ttatgcttct tggttccaat atcttactgg ggcaattatt atccttcttg
    60241 gtttgcacca aatggagatt ctacacttta aggggcttta taaggaaaag aggctacaac
    60301 tgcaaggaca ggggcaaaat ggtaagggct atagtcaggc atttttattg ggcttgacct
    60361 ttagttttgc ttggacgcct tgcgtggggc cggttctggg gtctgttttg gccttggcgg
    60421 cttcaggtgg ttcaggagct tggcagggag ctggtctcat gttggtgtat acgctgggct
    60481 tggcgctacc attcttgctt ctagctctga cctctagtta tgttttgaaa catttccgaa
    60541 aacttcatcc ctatctcgga atcctcaaaa aagtgggagg ttttctcatt attgtgatgg
    60601 gactcttggt tctgtttgga aatgcttcaa ttttaagtca attatttgaa taaaatggaa
    60661 aggaatatca atatgaaaaa atggcaaaca tgtgttcttg gagcgggttc gctcctttgt
    60721 ttgacggctt gttcaggcaa gtccgtgact agtgaacacc aaacgaaaga tgaaatgaag
    60781 acggagcaga cagctagtaa aacaagcgca gctaaaggga aagaggtggc tgattttgaa
    60841 ttgatgggag tagatggcaa gacctaccgt ttatctgatt acaagggcaa gaaagtctat
    60901 ctcaaattct gggcttcttg gtgttccatc tgtctggcta gtcttccaga tacggatgag
    60961 attgctaaag aagctggtga tgactatgtg gtcttgacag tagtgtcacc aggacataag
    61021 ggggagcaat ctgaagcgga ctttaagaat tggtataagg gattggatta taaaaatctc
    61081 ccagtcctag ttgacccatc aggcaaactt ttggaaactt atggtgtccg ttcttaccca
    61141 acccaagcct ttatagacaa agaaggcaag ctggtcaaaa cacatccagg attcatggaa
    61201 aaagatgcaa ttttgcaaac tttgaaggaa ttagcctagg aggtgtctta tgaatgataa
    61261 gttaaaaatc ttcttgttgc taggagtatt ttttctagcc ataaccggtt tctatgttct
    61321 attgatacga aatgcagggc agacagatgc ctcgcaaatt gaaaaggcgg cagttagcca
    61381 aggaggaaaa acagtgaaaa aaacagaaat tagtaaagac gcagacttgc acgaaattta
    61441 tctagctgga ggttgtttct ggggagtgga ggaatatttc tcacgcgttc ccggggtgac
    61501 ggatgccgtt tcaggctatg caaatggtag aggagaaaca accaagtacg aattgattaa
    61561 ccaaacaggt catgcagaaa ccgtccatgt cacctatgat gccaagcaaa tttctctcaa
    61621 ggaaatcctg cttcactatt tccgcattat caatccaacc agcaaaaata aacaaggaaa
    61681 tgatgtgggg acccagtacc gtactggtgt ttattacaca gatgacaagg atttggaagt
    61741 gattaaccaa gtctttgatg aggtggctaa gaaatacgat caacctctag cagttgaaaa
    61801 ggaaaacttg aagaattttg tggtggctga ggattaccat caagactatc tcaagaaaaa
    61861 tccaaatggc tactgccata tcaatgttaa tcaggcggcc tatcctgtca ttgatgccag
    61921 caaatatcca aaaccaagtg atgaggaatt gaaaaagacc ctgtcacctg aggagtatgc
    61981 agttacccag gaaaatcaaa cagaacgagc tttctcaaac cgttactggg ataaatttga
    62041 atccggtatc tatgtggata tagcaactgg ggaacctctc ttttcatcaa aagacaaatt
    62101 tgagtctggt tgtggctggc ctagttttac ccaacccatc agtccagatg ttgtcaccta
    62161 caaggaagat aagtcctaca atatgacgcg tatggaagtg cggagccgag taggagattc
    62221 tcaccttggg catgtcttta cggatggtcc acaggacaag ggcggcttac gttactgtat
    62281 caatagcctc tctatccgct ttattcccaa agaccaaatg gaagaaaaag gctacgctta
    62341 tttactagat tatgttgatt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc
    62401 cttaccgtat gtagggttac tgacttcgtc agttttatct acaacctcaa agctatactt
    62461 tgagctgact tcgtcagttt tatctacaac ctcaaagcgg tactttgaga aacctgtggc
    62521 tatcttccta gtttactttt tgatttttat tgagtataag aggtctttcc taagcagtta
    62581 gaggagaatt ttgctatact gatactagta aatggtaaag gagcagagca tgacctacac
    62641 aatcttaatc gtagaagatg aatatctggt aagacaaggt ttgactaaac tggtcaatgt
    62701 agcagcctac gatatggaaa tcatcggtca ggctgaaaat ggaaggcagg cttgggaatt
    62761 gatccaaaag caggttccag atatcatttt aaccgatatc aacatgcctc atctaaatgg
    62821 catccagttg gccagtttgg tacgagaaac ctatcctcag gttcatttgg tctttttaac
    62881 aggttacgat gattttgatt atgccttgtc tgctgtcaaa ctaggtgtgg acgactacct
    62941 gctcaaaccc ttttctcgtc aggatattga ggaaatgttg gggaaaatca aacaaaaact
    63001 agacaaggaa gagaaagaag agcagttaca agatttattg actaataggt ttgaaggaaa
    63061 catggcccag aaaatccagt ctcatctggc tgatagccaa tttagtttaa agtctttagc
    63121 cagtgactta ggttttagtc cgacctatct gagttctttg attaagaaag agttgggctt
    63181 gccttttcag gattatctgg tgagagaacg tgttaaacaa gccaagctct tgcttttaac
    63241 tacagatctg aagatttatg agatcgcaga gaaggttggt tttgaagata tgaactattt
    63301 tacccaacgt tttaagcaga ttgcaggtgt gacacctcgt cagtttaaga agggagaaga
    63361 ccgatgaagc gttcttctct tttagttaga atggttattt ccatctttct ggtctttctc
    63421 attctcctag ctctggttgg aactttctac tatcaatcaa gttcttcagc cattgaggcc
    63481 accattgagg gcaacagcca aacgaccatc agccagacta gccactttat tcagtcttat
    63541 atcaaaaaac tagaaaccac ctcggctggt ttgacccagc agacggatgt tctggcctat
    63601 gctgagaatc ccagtcaaga caaggtcgag ggaatccgag atttgttttt gaccatcttg
    63661 aagtcagata aggacttgaa aactgttgtg ctggtgacca aatctggtca ggtcatttct
    63721 acagatgaca gtgtgcagat gaaaacttcc tctgatatga tggctgagga ttggtaccaa
    63781 aaggctattc atcagggagc tatgcctgtt ttgactccag ctcgtaaatc agatagtcag
    63841 tgggtcattt ctgtcactca agaacttgtt gatgcaaagg gagccaatct tggtgtgctt
    63901 cgtttggata tttcttatga aactctggaa gcctatctca atcaactcca gttggggcag
    63961 cagggctttg ccttcattat caatgaaaac catgaatttg tctaccatcc tcaacacaca
    64021 gtttatagtt cgtctagcaa aatggaggct atgaaaccct acatcgagac aggtcagggt
    64081 tatactcctg gtcacaaatc ctacgtcagt caagagaaga ttgcaggaac tgattggacg
    64141 gtacttggcg tgtcatcatt ggaaaagtta gaccaggttc ggagtcagct cttgtggacc
    64201 ttgcttgggg ccagtgtcac atctcttctt gtctgtctct gcttagtgtg gttcagtctt
    64261 aaacgctgga ttgctccttt gaaggatttg agagaaacca tgttggaaat tgcttctggt
    64321 gctcaaaatc ttcgtgccaa ggaagttggt gcctatgaac tgagagaagt aactcgccaa
    64381 tttaatgcca tgttggatca gattgatcag ttgatggtag ctattcgtag ccaggaagaa
    64441 acgacccgtc agtaccaact tcaagccctt tcgagccaga ttaatccaca tttcctctat
    64501 aacactttgg acaccatcat ctggatggct gaatttcatg atagtcagcg agtggtgcag
    64561 gtgaccaagt ccttggcaac ctatttccgc ttggcgctca atcaaggcaa ggacttgatt
    64621 tgtctctctg acgaaatcaa tcatgtccgc cagtatctct ttatccagaa acaacgctat
    64681 ggagataagc tggaatacga aattaatgaa aatgttgcct ttgataattt agtcttaccc
    64741 aagctggtcc tacaacccct tgtagaaaat gctctttacc atggcattaa ggaaaaggaa
    64801 ggtcagggcc atattaaact ttctgtccag aaacaggatt cgggattggt catccgtatt
    64861 gaggatgatg gcgttggctt ccaagatgct ggtgatagta gtcaaagtca actcaaacgt
    64921 gggggagttg gtcttcaaaa tgtcgatcaa cggctcaaac ttcattttgg agccaattac
    64981 cagatgaaga ttgattctag accccaaaaa ggaacgaaag ttgaaatata tataaataga
    65041 atagaaacta gctaactccc agtcaattct gggagtttta tgcgtaattg ggcaaacttt
    65101 ctaggttgtc tatcttgcta aaaacaagaa aaaacggtat gatagaagag tgacaacaga
    65161 ggtaacagag atgaacgaga cacagattca aagagaaaca cgtcaggtag tggaagatgt
    65221 tttagaaaag accaatttga aacagggggc cctttttgtt ttaggtctat cttctagtga
    65281 ggtgctaggt ggtcagattg ggaaagaatc cagtcaagag attggtgagc tgatagtgga
    65341 gactatcttg ggtattctag gtagtagagg tatccattta gcagttcaag gttgtgagca
    65401 tgtcaatcgg gctctcgttg ttgaacgtca ggtggcagag cagtttggtc tggaaattgt
    65461 cagtgtccat cctactcttc atgcaggagg ttcggggcag ttggcagcct ttaagtttat
    65521 gcaggatcca gttgaggttg aatttatcaa ggctcatgct ggattggata tcggagacac
    65581 tgcaattggc atgcatgtca agcatgttca ggttccgatt cgccctattt tgagagagat
    65641 tggtcatgcc catgtaacgg cactgactag tcgtccaaaa ttaatcggag gtgcgcgtgc
    65701 gcactatccg caagatgcta ttaggaagtt ttgagaatga ataaaggaga taaaagtgtt
    65761 taaaaaagac cgtttttcaa ttcgtaagat taagggagtt gtaggctctg tatttcttgg
    65821 aagccttttg atggctcctt ctgtagtgga cgcagccacc tatcactatg taaataaaga
    65881 gattatttca caagaagcta aagatttaat tcagacagta aagcctgaca ggaatgaagt
    65941 tgtatatggt ttggtgtatc aaaaagatca gttgcctcaa acagggacag aagcatctgt
    66001 tttgacagct tttggtttgc tgactgttgg gagcttgctt ttaatctaca agagaaagaa
    66061 aattgctagc gtctttctag ttggaactat gggattggta gttcttccta gtgcaggggc
    66121 tgtagaccca gttgcgaccc tagcactggc tagtcgagag ggtgttgttg aaatggaggg
    66181 ctatcgctat gttggttatc tatcaggtga catcctcaaa acgcttggct tggacactgt
    66241 tttagaagaa acctcagcaa aacctggaga ggtgactgta gtcgaagttg agactcctca
    66301 atcaacaaca aatcaggagc aagctaggac agaaaaccaa gtagtagaga cagaggaagc
    66361 tccaaaagaa gaagcaccta aaacagaaga aagtccaaag gaagaaccaa aatcggaggt
    66421 aaaacctact gacgacaccc ttcctaaagt agaagagggg aaagaagatt cagcagaacc
    66481 agctccagtt gaagaagtag gtggagaagt tgagtcaaaa ccagaggaaa aagtagcagt
    66541 taagccagaa agtcaaccat cagacaaacc agctgaggaa tcaaaagttg aacaagcagg
    66601 tgaaccagtc gcgccaagaa aagacgaaca ggcaccagtc gagccagaaa atcaaccaga
    66661 agctcctgaa gaagagaagg ctgtagagga aacaccgaaa caagaagagt caactccaga
    66721 taccaaggct gaagaaactg tagaaccaaa agaggagact aaaacagcta aggggacgca
    66781 agaagaagat tacgtgggtg aggctcttgt tccagaacaa ttacctgagt ataaggtgac
    66841 tgaaggaaca ctcgttgaag aatcaactac agaacttgac tataaaactg aaacgactga
    66901 ggacccaacc aagtacacgg acgaagaaac tgtcctacga aatggtgaaa aaggaagtca
    66961 agttacaaaa acaacctata aaacaatagg aggggttaaa actgaccaag ttctttcaac
    67021 cagtacggaa gtcaccaagg agcctgtaaa tcaacaggta atccgtggta caaaaccaat
    67081 tgaagggaca acggttgaga caagagaaga aatcattcct tttgaaacaa aagaacaaga
    67141 agatgacact ttaaaacgcg gaacaagaca agtaactcaa gaaggtgtaa acgataagaa
    67201 acaaattact gaaacctata aaacaattcg cggagaaaaa acaagtgacg ctcctactat
    67261 cacagaaaca gtgattgaaa aacctcaaga caaaattatt aagaatggca caaaagagtt
    67321 agagaaacca accttggaat gggctaaaac agataaagat gtcttgaaga agagtgcgac
    67381 agctagttat acattgacta aaccagctgg agtagaaatt aaatcgatta aagtagctct
    67441 aaaagataat actggaacag ttgttaaaga agtaacggta gaagaaaata acttacaagc
    67501 tactttagac aacttgaaat attatcaagg ttatacacta tccacaacca tggtctatga
    67561 tcgaggtaac ggtgaagaaa ctgaaatatt agaagataaa gaagttcagt tagaccttaa
    67621 aaaagttgag attaaagata ttaaagaaac aagattgatg aaagtggatg agaatggaaa
    67681 tgaaacagat agtagccttc tagaaactgt tccagaaaat ctaacgtcat attatctaaa
    67741 aattaccact aatcataata aagtaacaag gcttgccatt actaatatag aggaagtaac
    67801 tgaggaggag acatccttat ttaaagttac tgcttcagct cctgatttaa tccaacgtga
    67861 ttcaaataat agtttgagtc aaacatacac ttattacata gagaaaccca aagcatcgca
    67921 aaataacgtt tactataact tcaaagattt agtagatgct atgcagaaaa atcctaacgg
    67981 tgagtttaaa ttaggatcgg atttaaatgc aacaaatgta cctacaccaa gtaaatcata
    68041 tgtaacaggt aaatttacag gtcacttaac aagtgttgat ggtaagcatt tctccattca
    68101 taacactgct cgtccattat ttgatagagt tgaagggggt tctatcaaaa atattaattt
    68161 aattaacgtt aatattaata tgccttgggc aaatcaatta gcttcattag ctcaaacagt
    68221 gaaaaatgca actgttgaaa atattaaagt aacgggtact atcgttggta ataacaatgt
    68281 tgcgggtatt ttggataaat tagatgatgc aggtattatg actaatgttg cttttatcgg
    68341 aaaagttcaa tctgttggtg ataaagggtg gaacttggct gggattgcat ctgagattta
    68401 tcgaggcaat ttaaataaag cttatgcaga tgttgaactt aaaggtttaa atactcgtgc
    68461 aggtgctata gtaggacatt tagctcatga ttttaatcca agagatgttg gtgcttggtc
    68521 taatgtaaga aattctgtag ccaaaggtac tattgatgtt gctagaggtg atgtaggcgg
    68581 tttaattggt aaagactggc cttggggaac cattgataac aatatcagct tagtgaatgt
    68641 taagcgtggt gatattttct ttggttctaa tgatatggat gatgaatttg taagcaattg
    68701 gattaaacct aataatgcaa cagttatcgg tgtgagttct ggagataaaa cccataaaca
    68761 atcgtctaaa attaaagaaa tttcacaggt agaagctgat aagaaaatta aggatatggg
    68821 tatcactgct gatacatttg aagtaactga gcatttggtt gataagttga atcgccgtat
    68881 attacgtgat gaagaataca aaacaattca agattataat gcaaatcgtg agcttgttta
    68941 tcgtaatgtt gaaaaactcc aaccgttcta caacaaagaa tggattgtga atcaagggaa
    69001 caaacttaca actgatagtc cattaatgaa taaagaagta ttgtctgtga ctgcaatgaa
    69061 aggtaatgac tttattacag accttacaga tgctgaccat attatggttc attacgcaga
    69121 taagacaaaa gatatcttta cgatttctcc taaagactct caagttaagc aagtaaaaga
    69181 atacagtgtc gcagagcttg gtgaagtcgt ctatacacca aatatggttg ttaaagatcg
    69241 tgcagattta attagtgcta ttgaaggtat tttaagtcca attgaattac aatctgatcc
    69301 aatttatcaa cgattaggaa gaactgggga taacagagtt aatgcaatta agaatcttta
    69361 cttagaagaa agctttaaag aagtaaaaga tcatcttaat acatttgtga caaaattagt
    69421 tgaaaatgaa gatcatcaac tgaatacaga tgaagctgca aaacgtgcct tgattaagaa
    69481 aattgaagat aacaaagctg ctgtcctgtt aggattaaca tacctaaatc gttattacgg
    69541 tgtgaaattt gataacttca atattaaaga attaatgcta ttcaaaccag atttttatgg
    69601 taagaatgta agtgttttag atcgattaat agaaattggt tcaaaagagg actatattaa
    69661 gggaagtcgt acacaggagt ccttccgtga agtggtggcg aaaaatactc tttctggaaa
    69721 cttacatgac ttcttgacct acaatatgaa actattcaca aatgaaacag acataaatgt
    69781 ttggtttaag aaagctattg aaaataatgc ttatgtagtt gaacaaccgt caactaaccc
    69841 tgcatttgct aataaaaaat atcgtctata tgaaggactt aataacggac aacatggacg
    69901 catgatttta tcgcttctga acttgaaaga tgcacattta tttatgattt caacatataa
    69961 tactatctca tttagttcgt ttgaaaagta tggtaaagat acagaagaaa aacgtgaaac
    70021 gttcaagagt gaaatcaata aacgtgctaa agagcaagtt aattacttag atttttggtc
    70081 acgccttgcc actgataatg tccgcgataa acttcttaag agtcaaaatg tagttccaac
    70141 tcctgtatgg gataatcatg gtgcacccgg tggttggcct gatagatttg gtcatcgaaa
    70201 agataaaccg gattatgcac ctattcgtga attctttgga cgtattgata agtatcatga
    70261 ttataagtat gggtatggag cgtatgctta catctttgct gatccacagc ctatggatgc
    70321 tgtatatttt gttatgtcgg atttaataag tgaatatggc acatctgcct ttacacatga
    70381 gactacccac gtaaatgacc gaatggcata tctgggaggt catagacatc gacagggtac
    70441 agatcttgaa gcatttgctc aaggtatgtt acaaactcca gcagaacatg gacatcaagg
    70501 tgaatatggc gcacttggat taaatatggc atttgaacgt tcaaatgatg gaaaccaatg
    70561 gtataatcca gatcctacca aacttcaaac acgtgaccaa atcgaccatt acatgaagaa
    70621 ctacaatgaa gctatgatga tgctcgatta tgcagaagct gaggctgttc ttcctaaggt
    70681 taaaggtgac aatagtaagt ggttcaagaa aattgatcgc gaaacacgtc gaccaatgga
    70741 cagaaataaa ctaagtggtc ctcaccaatg ggacaaagtg cgtgatttga tagacgctga
    70801 gaaaacaact aaccttgaaa ccatcgatga cttggtaaat aataatttca tgaccattca
    70861 cggaaatcca ggtaataagg tcttccaccc agaggacttt ggtacggcat atgtcaatgt
    70921 taatatgatg gctggtattt atggcggtaa tacgagtcaa ggtgcccctg gttctctatc
    70981 cttcaaacat aacgccttcc gtatgtgggg ttactatgga tatgaacatg ggttcattga
    71041 ctatgtttca agcaaacatc aaggtgcagc caataaagaa aataacggtc tattaggtga
    71101 tgatttcatt attaagaaag tttctaataa ccaattttca aaccttgaag attggaagaa
    71161 gcaatggtat ggggaagttc ttacaaaatc taaaaaaggt tttgcaccaa ttgaaattaa
    71221 tggcactcaa atttcaacct atgaacagtt gaagactatg tttgatgagg ctgttactaa
    71281 agatttaacg gaactaaacg atagtagtat taaagacaaa taccgaaata cagttgtctt
    71341 gaaatcgaaa gtctttaaag ctctccttaa aaacacagac ggtttctctg gtgatctatt
    71401 tactgcacca caagcataga atgaataaaa tcgtaaaaag gtagatcagc tttgtctgta
    71461 tctgcctttt tatgctatac ttaaggtatg catagaaaaa cagtgattga ttttaggact
    71521 ttgggggaga gatatacctt taccaagcct attaaagagt tgaaaacgag aaatgtagaa
    71581 gaagtggcag atttgctggc acaagtggaa agctaccaag agcaaggtta ttatgtggtg
    71641 gggtatgtca gctacgaggc tgcacctgct tttgaggaaa aattagcagt tcacaaggat
    71701 cccctactgg gagagtacct gctttatttt actgttcatg atagcgtaga aacttcccct
    71761 attcctctga cttatgagga tattgatttg ccctcaaatt ggcaggaagt aacgtctgca
    71821 gcagactatg aaaaggccat tgcccaaatt caccatcatt tacggcaggg agatacctat
    71881 caggtcaact acaccgtcca acttaagcaa aagttaaatg ccaatccttt tgccatctac
    71941 aatcgtatgg tggtagagca ggaggcgggc tacaatgcct atgtggaaca tgacgagatg
    72001 gcagtgattt ccatgagccc agagctcttt tttgagcaaa atgatcgcga gttgacaaca
    72061 cgaccaatga aggggacgac tcagcgtggg gtaactgacc aagaagatct tgaacaggcc
    72121 agttggttgg aacaggatcc caaaaatcgc tctgaaaata tgatgattgt ggacctcttg
    72181 cgcaatgata tgaaccgtat ttctgaagtt gggagcgagc acgtggagcg tctgtgtcag
    72241 gtagagcagt attcaactgt ttggcagatg acttcgacca tcaagagtca gttgcgagag
    72301 gatgtggacc ttgttgaaat cttccgctca ctctttcctt gtggttccat aacgggtgca
    72361 ccgaaaattg cgacaatgga gattatcaag gacttggagc ctcaaccgcg tggagtctac
    72421 tgtggaacga ttggtctctt gcttccaaat ggacgacgga tttttaatgt ggccattcgt
    72481 accattcaac ttcacaaagg tcaagccatt tatggagttg gcggagggat tacttgggat
    72541 agcacatggg aatctgaata ccgagaggtt catcaaaagg cagcagttct ttatcgtaaa
    72601 caagctcgct tccaactgat tacgacaggg gaaatcagcc agaagaacct gttgtttgaa
    72661 gatcaacatc tggaaagact gagaaaagct agtcgttatt ttgcctttcc ttttgatgca
    72721 gaagacttgg gacacaagat tgaggaagag tgtcaggatt gtgaagctaa tcgagattac
    72781 cgcttgcgaa tcagccttag caaatctgga gagatagaag tcaatcgtca agtattaacc
    72841 cctctcagta caagcttttg tcaggcccaa gtctgccttc aggaagctgc tttgaatcaa
    72901 tcctttacct actttaaaac cactcaccga ccgcatttga gcctaggaga acaagagaag
    72961 atttaccaca ataagtcagg agaactgctt gaaacctcta taggaaattt ggttctgaaa
    73021 atcgctggaa aactctacac accgcctatc cgacttggaa tcttgccagg aatttaccgt
    73081 cagtatttgc tagaaacagg acaggtagaa gagaaagtct tgaccttggc agatttagcc
    73141 caagcagaag ctatttacgg ctgtaatgca gtgagaggct tgtatgaact aagccttgag
    73201 gagaactaga tgaaactgat atttttgcat gggttagggc agtcagcaga gtcttggaaa
    73261 gaagttcgga atctactgac agattatcct tctgaggcta tcgagttatt tccttctgga
    73321 gttagtaact atcaacaagc taaggagcga gtttatcagc acctagctca agagacagaa
    73381 ccttttgttt tgattggatt gtccttaggt gctgccctgg cactagaact ttccagttac
    73441 gatttaccaa atcttcgagc tttgattctg tcaagatgcc cgcttaaatt agcagggaat
    73501 atcctatttt atcttcagtt gctgattttt aaactacttc ccaaaagagt atttgaaaaa
    73561 cagggagcag acaaggctct tatggtcgga gtttctgagg agttgaagac acttgattta
    73621 acggatatag caggaacttg cccttatcca accttactaa tttgtggtat caaagataaa
    73681 ccgaatctta gttctatgag aagtcttcat aaactaatat cagaatccca atttcagatt
    73741 atcccagatg gccctcatgt cttgaataag gcaaaaccaa aggagtttgt agaaaagacc
    73801 agaagtttcc ttgaattgct gaaataagtt tgataaaata atattgaaat cgatatcata
    73861 attatgggag aaagaaatga ataaacgtct atttttaaaa atgagtctgg tgacgttgcc
    73921 aattttagcc ttgttttcac aaccagtttt ggcggaagaa aacatccatt tttcgagctg
    73981 taaggaagct tgggcgaatg gctattcgga tattcacgag ggagaacctg gttattctgc
    74041 caagttagac cgtgatcatg atggtgtggc ttgcgaattg aaaaatgctc ctaagggtgc
    74101 ttttaaagca aaacagtcaa cggctattca aatcaacaca agttcagcaa caacaagtgg
    74161 ttgggttaag caggacggcg cttggtacta ctttgatgga aatggaaatc tagtgaaaaa
    74221 tgcatggcag ggaagctatt acctgaaagc tgatggtaaa atggcccaga gtgaatggat
    74281 ttatgactct tcttatcaag cttggtatta tttgaaatca gatggttctt atgcaaaaaa
    74341 tgcatggcaa ggagcttatt accttaaatc aaacggtaaa atggcacaag gtgagtgggt
    74401 ttatgattct tcttaccaag catggtatta cttgaaatca gatggttcat atgctcgcaa
    74461 tgcatggcaa ggaaactact atttgaaatc agatggtaaa atggctaaag gtgaatgggt
    74521 ttatgatgcc acctatcaag cttggtatta tttgacatca gatggttctt atgcttacag
    74581 tacatggcaa ggaaattact atctaaaatc ggatggtaaa atggctgtca atgaatgggt
    74641 tgatggtgga cgttattatg ttggcgctga cggagtttgg aaggaaggtc aagcaagtac
    74701 agtttcttct agtaatgata gcaatagtga atattctgct gctttaggaa aggcaaaaag
    74761 ttataattcg ttattccaca tgtcaaaaaa acgtatgtat agacaattaa cttctgattt
    74821 tgataaattt tcaaatgatg cagctcaata tgccattgat catttagatg attaacagat
    74881 actggtaggc gaaaaaattc cttataattc atttacgcaa acctttgcat aagtgaatgg
    74941 attttgatat actagtactg taagcatttt caattactac acaatgaaaa aggagaatat
    75001 gatgagtcaa aagattattg ggattgacct tggtggaact tctatcaaat ttgcaatctt
    75061 aacaacagca ggagaaatcc aaggaaaatg gtcaatcaag accaacattt tggatgaggg
    75121 aagtcatatc gttgatgata tgattgagtc tattcaacat cgtttggact tgcttggatt
    75181 ggcagcagcg gacttccaag gcattggaat gggatcacca ggtgtggttg accgtgacaa
    75241 agggactgtt atcggtgcct acaacttgaa ctggaaaacc cttcaaccaa tcaaacaaaa
    75301 gattgaaaaa gctttgggca ttccattttt catcgataat gatgccaacg tagcagctct
    75361 tggtgagcgc tggatgggtg ctggagataa ccaaccagac gttgtcttta tgacactcgg
    75421 tactggtgtt ggtggcggta tcgtcgcaga aggcaaattg cttcacggtg ttgctggtgc
    75481 agcaggtgag cttggtcaca tcactgttga ctttgaccag ccaatctcat gtacttgtgg
    75541 taaaaaaggc tgccttgaga cagttgcttc agcaacaggg attgtcaact tgactcgtcg
    75601 ctatgccgat gaatacgaag gcgatgcagc cttgaaacgc ttgattgata acggagaaga
    75661 agtaactgct aagactgtct ttgatctcgc aaaagaagga gacgaccttg ctttgattgt
    75721 ttaccgtaac ttctcacgtt acttgggaat cgcttgtgct aacattggtt caatcctaaa
    75781 cccatcaaca atcgtcatcg gtggtggtgt gtcagctgcg ggagaattcc ttctacaagg
    75841 tgttcaaaaa gtttacgatg aaaatagttt cccacaagta cgcacatcta ctaaattagc
    75901 tcttgcaact ctaggaaatg acgctggagt tatcggagca gcatcacttg tattgcaata
    75961 agataatgag agaggaaaat gctaacctag agttagtaat gttcctcttt tattttttat
    76021 gctatactag ttaggacaat gaatgaggtg agagtaaatg acaaaagcag atacgatttt
    76081 taaagagaat attgaacgca ttctaaagga aggtgttttc tcagagcagg ctcgtcctaa
    76141 gtacaaggat gggactgttg ctaattccaa gtatgtaact ggtgcctttt ccgagtacga
    76201 cttatctaaa ggagaatttc ctatcacaac cttgcgtccc attgcaatca aatccgccat
    76261 caaagaagtt ctctggattt accaagacca gtcaaatagc ttagaagtgc ttaatgacaa
    76321 gtacaatgtt cactactgga atgactggga agttggagac acgggaacca ttggtgagcg
    76381 ctatggtgcc gttgttaaga aacacgacat tatcaataag cttctcaaac agttggaaac
    76441 caatccttgg aaccgccgca atattatttc gctctgggat taccaagctt tcgaagaaac
    76501 agatgggctg ctcccgtgcg cctttcagac catgtttgat gtccggcgtg ttgatgggga
    76561 aatctatctg gatgcgacct tgacccagcg ctccaatgat atgctggtgg cccaccacat
    76621 caacgctatg cagtatgtgg ctttgcagat gatgattgcc aaacattttg gctggaaggt
    76681 tgggaagttc ttctacttca tcaacaacct ccatatctat gataatcaat ttgaacaagc
    76741 tcaggaattg ctccgtcggg agccgtcaaa ctgccaacca cgcttggttt taaatgttcc
    76801 tgatgggact aatttctttg atatcaaagc agaagatttt gagttggtgg attatgaccc
    76861 tgttaagcca cagttgaagt ttgacctagc tatttaaaag aatagaaaaa agaagttgag
    76921 aataatccca acttcttttg tttcttaacg tgatacgcgg cgacgagctg cttttttacg
    76981 gttttcttcg atgaaagctg ctttttgctc ttctggttcg attactttct ttttaaatgc
    77041 gtatactgca cctgcaacgg cagcgacagt tcctgcgaca cctgttacaa gacctttagc
    77101 gaatccttta gccatgagtc ttcctccttt atattctcaa tcagccagcc tcctcaagag
    77161 gtcacatttt tctgactgac ctttttgtgt tataataata gtaacgaaaa aatgggaatt
    77221 tttcaaggaa aaaagatgaa aacaaaaata attgtgattg ttggaccgac tgctgttgga
    77281 aagacggctc tagctattga agttgcaaag cgttttaatg gcgaagtggt tagtggagat
    77341 agccagcaag tctatcgagg acttgatatt gggacggcca aggctagtcc agaagagcag
    77401 gcagctgttc ctcatcattt aatcgatgtt agagagataa ccgagtctta ctcggctttt
    77461 gattttgttt cagaagctaa gatgactatt gagggtattc acaaccgtgg caagctagcc
    77521 attatcgccg gtgggactgg actttatatc cagagcttgc tagaaggtta ccacctaggt
    77581 ggggagactc ctcatgagga gattttagct tatcgagcta gtttggagcc atattcagat
    77641 gaggaattag cccatttggt ggatcaagca ggccttgaga ttccccagtt taatcgtcgt
    77701 cgtgctatgc gtgccttaga aattgcccat tttggtcagg atttggaaaa tcaagagacc
    77761 ttgtatgaac cgctgattat ctgcttggat gatgaacgta gtcaacttta tgagcgtatc
    77821 aaccaccgag tggatttgat gtttgaggct gggcttttgg atgaggccaa gtggctgttt
    77881 gaccattccc ctaatgtaca ggctgctaaa ggaattggct ataaggaact ctttccttat
    77941 ttccgtggag agcagacctt ggaggaagct cgtgagagtc tcaaacaggc tactcgtcgt
    78001 tttgccaagc gtcagctgac ctggttccgt aatcgcatgc aggtcacctt ttatcagatt
    78061 ggagaatctg gtgtacaaga ccgcatttta agccagatag aggagttttt agatgattga
    78121 aacggagaaa aaagaggagc gggtcctgct gattggtgtg gaattgcagg gtatggacag
    78181 ttttgacctc tccatggaag aattggctag tttagcgaaa acggcagggg cagtcgttgt
    78241 agatagctac agacaaaaac gtgaaaaata tgattccaag accttcgtcg gctctggtaa
    78301 gttggaagag attgcgctta tggtggatgc agaagaaatc actactgtca tcgtcaacaa
    78361 ccgtctgacc ccaaggcaga atgtcaatct agaggaagtt ctcggtgtta aggtcattga
    78421 ccgtatgcag ttgattttgg atatctttgc catgcgggct cgaagccatg aagggaagct
    78481 ccaagtccac ctagcccaac tcaaatacct cttgcctcgc ttggttggtc aggggattat
    78541 gctcagccgt caggcagggg gaattggttc ccgtggtcct ggtgaaagcc aactggagct
    78601 gaaccgtcgt agcgttcgca atcaaatcac ggatatcgag cgccagctta aggtggttga
    78661 gaaaaatcgt gcgactgtca gagaaaaacg tttggagtct agcaccttta agattggttt
    78721 gattggttat accaatgctg ggaaatcaac tatcatgaac atcttgacca gtaagaccca
    78781 gtatgaagca gatgagctct ttgcgactct ggatgcgaca accaagagta ttcatctagg
    78841 aggcaatctc caagtaactt tgacagatac cgttggcttt atccaagatt tgccgacaga
    78901 gttggtgtcc agtttcaagt caaccttgga agaaagcaag catgtggacc ttctggttca
    78961 tgttatcgat gctagcaatc cttaccacga ggagcatgaa aaaacggttc tctccatcat
    79021 gaaagacctg gacatggaag atattcctca cttgacgctt tataataaag cggatttggt
    79081 ggaggatttc acgcctaccc aaacgccata taccctcatt tctgccaagt ctgaggacag
    79141 tcgtgaaaac ttgcaagcat tattgctaga taagattaag gaaatttttg aagcatttac
    79201 cctgcgagtg cctttttcaa agtcctacaa gattcatgat ttagagagtg ttgcgattct
    79261 tgaagaacgt gattatcagg aagacagcga agtgattaca ggctacattt ccgagaaaaa
    79321 taaatggagg ttagaagaat tttatgactg atattaaaac tttggctcta aagtatggag
    79381 gttatacaag tctggacaag gtctatctgg atcagcttct agctggtaaa acagagcagg
    79441 agcagttaac acttattaca cctccgccaa gtgttgttaa tgcctacttt gcagaactct
    79501 atcagaaaaa gagtcctcag gctgcgacgg attattttgc agaactcagt caggaactga
    79561 atctttacaa tactgagcca agtttcaccc tagaaaataa gtcttttatt cggcttaatc
    79621 tgtctggtaa atcctttggt ttttgttatg agagtgacgg ctttggtcgg attttctctg
    79681 aaaatgagga gaaaatctcg gatgacttgc tctttgaaat tgcgcaaatt ttcccccatc
    79741 aattagtctt tgaagagtct ggtaagattt acatgaagcc tgtcgaggac gaggaagttg
    79801 tcagcctaga aagtctcaca gctttgactg atttggaaag attggctgat ggtcgaaaac
    79861 gtctcaaagg ctacagccaa gaggatttat tgaaagaagc tgctgctttt tctggcaaac
    79921 gctatttccg atcggaaaac cgcacagcca tgttatatat tgattaatta gaaagtatcg
    79981 aatggatatt caatttttag gaacgggggc tggtcagccc tctaaagccc gcaacgtttc
    80041 aagtctcgcc ctgaaacttt tggatgagat taacgaagtt tggctctttg actgtggaga
    80101 aggtacgcaa aatcgcattc tggaaaccac aattcgacca cgtaaggtca gcaaaatctt
    80161 tattacccat ctgcatggag accacatttt tggtttgcca ggtttccttt ctagccgtgc
    80221 ctttcaggcc aatgaagagc agacagattt ggaaatctac ggacctcaag gaatcaagtc
    80281 atttgtctta accagccttc gtgtgtcagg ttctcgtctg ccctaccgca ttcatttcca
    80341 tgagtttgac caagattctc tgggtaaaat tcttgaaacc gataaattca ctgtgtatgc
    80401 agaggagctg gaccacacta ttttctgtgt tggctatcgt gtcatgcaaa aggatctaga
    80461 agggacgctg gatgctaaaa aactcaaggc tgctggtgtt ccgttcggcc cgctttttgg
    80521 taaaatcaaa aacggccagg atcttgtttt ggaagacgga actgaaatca aggcagcaga
    80581 ctatatctca gcgccacgtc caggtaagat tatcactatt ttaggagaca ctcgaaaaac
    80641 ggatgccagt gtgcgtctgg ctgtcaatgc agatgtccta gttcatgagt ccacttatgg
    80701 caaggatgat gaaaaaattg ctcgtaacca tggtcactca actaatatgc aagctgcaca
    80761 agtagcggta gaagcaggtg ccaaacgcct cctactcaac catatcagtg cccgtttcct
    80821 ctcaaaagat ataagcaaac tcaagaaaga cgctgccaca atttttgaaa atgtccatgt
    80881 ggtcaaagac ttggaagaag tggaaatcta gcagtcacag aaaggataag tatgcctact
    80941 attctcatta ccggagctag cggtggtcta gctcaagaaa tggtcaaact cctgcccaat
    81001 gaccaactca tcttgcttgg tagaaataag gaaaaattag cccaactcta cggaaattat
    81061 tcccatgcag aattgattga aattgatatt accgacgatt cagccctaga agctctggta
    81121 actgatcttt atctccgcta tggcaagatt gatgtcttga ttaacaacgc tggttacggg
    81181 atttttgagg gatttgacca aattgctgat aaagacattc accagatgtt tgaggtcaat
    81241 acctttgccc tgatgaatct gtctcgtcac cttgcggctc gtatgaagga aagcagcaaa
    81301 gggcatatca tcaacatcgt cagcatggca ggtctaatag ctactggcaa gtctagtctt
    81361 tactcagcga ccaagtttgc ggctattggt ttttcaaatg ctctgcgact cgaacttatg
    81421 ccctatggag tctatgtgac aacagtcaat ccaggtccaa tccgaacagg attttttgac
    81481 caagctgacc cagatggaac ttatcttaaa tcggttgacc gcttcctctt agaggcagat
    81541 gcagtggcta aaaagattgt caagattata ggcaaaaata aacgagaact caatctcccg
    81601 attttgttga acctagccca taagttttat actctctttc ccaagctagc tgataagttg
    81661 gcaggggaaa cttttaatta taagtaaaaa gaaccaatgt gcaggttgtt gctagcctac
    81721 atattggttc ttatcatttc tcaactatca aactgaactt cttctagtag atagtcgata
    81781 aagcgttcgc ccatcttaga taggctggtt ttctcatgct ggatatagac cagctcaatc
    81841 gggtcatcaa tatccagtgg gatagaaacg atattgtctc cgtttaggtt gctgttcaaa
    81901 atccctgtcg caatggtata accatccaaa ccaatcaaga gattaaagag ggtggcacgg
    81961 tcactgacca caatggattt cttgtggtgt tcttgagaaa gaatctcttc tgaaaagtag
    82021 aaggagttgt gcgtcccttg gtcatagctg aggtaaggga aattctccaa atcagacagt
    82081 ttcaccttgt ctttctttgc cagagggttg gtcttgctga caaagatatg cggttgcgct
    82141 gtgaagagat ggtgggctag caggtgattg tcatccagca tcttggttaa aacatcacgg
    82201 ttgtaactgt ttaagaagag gaccccgacc tcactgcgga agttcttgac gtcgtcgata
    82261 atctcccaag tccgagtttc acgaaggaag agttcgtatt tctccatatc gcttttcttg
    82321 agcaaagaga caaaggcatt gaccacaaag gcatagtgtt gagacgaaac gctaaagagt
    82381 tcgcggtggg cgacaggatt tttatagcgt tcctccagaa gctgggtctg ctcgacaacc
    82441 tgacgggcat aagagagaaa ctccatccca tcacgggtca aggtgattcc cttgggattg
    82501 cggataaaga tctcaatgcc catttcattt tccaaatctc gcactgcatt ggagagactt
    82561 ggctgagtga taaagagttg cttggctgcc tcattcatgg agccagtttc gacgattttg
    82621 ataatataat gtaattgttg aattctcatg tttttattgt accatacttg ccttagaatc
    82681 gctaaagaag ataggaaaat aaggagcatt gtgtgagtct cttcttgaaa aaaacacaaa
    82741 attttgctag aatgagtctt atgaaaacat tctatgatgt gcagcaattc ctcaaacgat
    82801 ttggtattat tgtttacatg ggaaaacgct tatatgatat tgaactgatg aagttggaac
    82861 tatctcggat ttacgatgca gggttgatgg ataaattaga ctatctagag gcagaagcag
    82921 ttcttcgcag agagcacaag gtagaattgg attatattga gaaaaatgga gaaaagaact
    82981 aatggttact tggattttgt gggcacttat actagcaatg ttggcgtgga tgggctttaa
    83041 ctatcttcgt attcgccgtg cggctaaaat tgtggacaat gaggagtttg aagccttgat
    83101 tcgtacgggt caattgattg atttgcgcga cccagcagaa ttccacagaa aacatatcct
    83161 tggtgcacgc aatattcctt caagtcagtt gaaaactagt cttgcagccc ttcgtaaaga
    83221 taaacctgtc cttctctacg aaaaccaacg tgcgcaacga gttacaaatg cagctcttta
    83281 cttgaaaaaa caaggttttt ctgagattta tatcctttct tatggcttgg attcttggaa
    83341 agggaaagtg aagactagct aaccttattt ccaaattagt cgaatgatag gatgaagata
    83401 ttgttttata gtataattaa tttgtataaa atttaaggag ttcttagaac atgaaagaaa
    83461 agaagaaaaa tccacttttt gtgggtatct tgtcgattat tcttggtttg ttatttccaa
    83521 ttgtaggcct gattttgggt atcataggat tggtcttggc tatttcatac caaaaagagt
    83581 cacaattaga ctataaaata gaaaagattc ttaatatctt aggaattgtg atttctgtag
    83641 ttaactggat tgtagcaatc gccttaattt ttcggtaaat aaaagaaaaa agctttagtt
    83701 ttaaagcttt ttttgtttta tcgactcatc tctaaatagt ttttaatgat ttgtaactct
    83761 ttttggttca aagggcggta gttaccttct gctaaatctg ggttcaatgt gaagtcccca
    83821 aattggattc ttttgaggct agtcacctta acaccaaccg agaggaacat tttcttgatt
    83881 tgatgaaatt ttccttctga aatggtgata gaggcttgac tgagggaggg acttgcagat
    83941 agaatctcta gttttgcggg tttacagaca gtaccatcta aaaagacaat tcccttttga
    84001 aaggcttgga tatggtcagg tgttagaagt ccattaacct ggacttggta agtcttatcg
    84061 acatgatatt ggggatggag gagctgaaag cccaagggac cgttatcggt caagaggagg
    84121 agtcccgttg tatctcggtc cagtcggcca acggcataga gcttgtcaga ctggatgtca
    84181 gatggaagca ggtccatgac ggtcggaagt tccttgtctt tgttggctgt aacgacacca
    84241 gcaggtttat gaagcataag ataggtgtgt tcatagcctt gaatgattcg atcctgaaaa
    84301 aggagttctt gtagtcctgt atcgatattt tgagctaggg agcgggctgg gcaaccatcg
    84361 actagaattt cccctctgag gagtgcttgc ttcatggcct ttcggctaac tttttcttgg
    84421 gctaataaat tatctaaacg catactgtgc ctatcttatc ataagtcgct tgctttgaaa
    84481 aggcttgacg tgaaaagaaa agcggagtga aaacatttac acttgcttga gttatgttat
    84541 ttacttgaaa ttatggtata atcgttcagt tagaaaataa attttgaata ttatagagga
    84601 aatcatgaca aaattaagag aagatatccg taacattgcg attatcgccc acgttgacca
    84661 cggtaaaaca accctggttg acgaattatt gaaacaatca gaaacgcttg atgcacggac
    84721 tgaattggca gagcgtgcta tggactcaaa cgatatcgaa aaagagcgtg gaattaccat
    84781 ccttgctaaa aatactgccg ttgcttacaa cggaactcgt atcaatatta tggacacacc
    84841 aggacacgcg gactttggtg gagaagttga gcgtatcatg aaaatggttg acggtgttgt
    84901 cttggtcgta gatgcctatg aaggaaccat gccacaaact cgtttcgtat tgaaaaaagc
    84961 cttggaacaa gaccttgtcc caatcgtggt tgttaacaaa atcgataagc catcagctcg
    85021 tccagcagaa gtagtggatg aagtcttgga acttttcatc gagcttggtg cagatgacga
    85081 ccagcttgat ttcccagtgg tttatgcttc agcgatcaac ggaacttctt cattgtcaga
    85141 tgatccagct gaccaagaag cgactatggc accaatcttt gacacgatta tcgaccatat
    85201 cccagctcca gtagataact cagatgagcc tttgcagttc caagtgtcac ttttggacta
    85261 caatgacttc gttggacgta tcggtatcgg tcgtgtcttc cgtggtacag ttaaggttgg
    85321 ggaccaagtt accctttcta aacttgacgg tacaactaaa aacttccgtg ttacaaaact
    85381 cttcggtttc tttggtttgg aacgtcgtga aatccaagaa gccaaagcgg gtgacttgat
    85441 tgccgtttca ggtatggaag acatctttgt cggtgaaacc atcactccga cagatgcagt
    85501 agaagctctt ccaatcctac acatcgatga gccaactctt caaatgactt tcttggtcaa
    85561 caactcacca tttgctggta aagaaggtaa atgggtaact tctcgtaagg tggaagaacg
    85621 cttgcaggca gaattgcaaa cagacgtttc ccttcgtgtt gactcaactg attcaccaga
    85681 taaatggact gtttcaggac gtggagaatt gcacttgtca atccttatcg aaacaatgcg
    85741 tcgtgagggc tatgaacttc aagtatctcg tccagaagtt atcgtaaaag aaatcgacgg
    85801 tgttaaatgt gaaccatttg aacgtgtaca aatcgacact ccagaagaat accaagggtc
    85861 tgttatccaa agcctttctg aacgtaaagg tgaaatgttg gatatgattt caactggtaa
    85921 tggtcaaact cgtttggtct tccttgttcc agcgcgtggt ttgattggat actcaactga
    85981 gttcttgtca atgactcgtg gttacggtat catgaaccat accttcgacc aatacttgcc
    86041 attgattcca ggggaaattg gtggacgtca ccgtggtgcc cttgtttcta tcgatgctgg
    86101 taaggctaca acttactcaa tcatgtctat cgaagaacgt ggtacgatct ttgtcaaccc
    86161 aggtactgag gtttatgaag gaatgatcat cggtgaaaac tctcgtgaaa atgacttgac
    86221 agttaacatc acgaaggcaa aacaaatgac caacgttcgt tcagctacta aggaccaaac
    86281 agctgttatc aagacgcctc gtatcttgac acttgaagag tctcttgagt tcttgaacga
    86341 cgatgagtac atggaagtaa cgcctgagtc tatccgtttg cgtaaacaaa tccttaacaa
    86401 agcagagcgt gagaaagcta acaagaagaa aaaatcagct gaataagagc tagaaagaga
    86461 gaaagatggt ctatttagtc ctaggaattt tactgctcct actctatgta tttgcgacac
    86521 cagaaagcat taaagggact gtcaatatcg tcgctatggt atgtatttta gtggcactct
    86581 tgattttatt ggttctatct tttctgaaaa tttttcaatt accaacagaa atattcctag
    86641 caatagccat gttgatccta gcttacttta gtgttagaga catcacactc atgccagtca
    86701 aaaaaagtaa aagaagataa aaagagagtt ttggctctct tttttgctag gaattttaca
    86761 agattgcaat ttatttttga gttatcacca tctcttttgt ttggataata tgaatgggaa
    86821 aaacttgaat aaaattcttt aatggcatct attttatatt tggttagtac tggttgcata
    86881 ttattttgaa ataaaactac tatataatat tattaataga ggtaatatag taaaatatct
    86941 aaaaaattcg attttttcct tgacaacaaa taataaaaat attattctta tcacataaga
    87001 aagcggtttc aataaaagag agaggaggat ttattttgtt gcattgttgc tcagggtgtg
    87061 ctttttttga aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc
    87121 ttatttcaag ttttacatta ttgggagctg catcagctgc tgtacaatat ccagatggag
    87181 gagtatggac atatggagaa ggttcaggag gtggttgggc tttttcaaat tactatcatg
    87241 gtaaaaaata tcattattca tccatcgtga gcagatggga tggtcattct gataaaggag
    87301 aagcagttgc aggaaaaact tcagaggctt ggatttggac taaatttggg gaacaagtat
    87361 catttttcta tgactatgac gactaatatt tagttttctt agataattcc ccttgtaaga
    87421 aattacaggg ggaattttgt ttacaaggag tctactatga agaaactatt catattatta
    87481 tcaacttttt ttctcagctt cttccttgct tggattattg tcttacgtgc gccacaatat
    87541 ttatatgcaa gctatgattc cgtttcttta cttcgtgtca aaaaagatac tcaggaaccg
    87601 acgcgtgagg tatttgaaca ggaattggag aattttgcaa actcagaaca gagtttaata
    87661 gctagaagaa ttgtagagcc gagtaaggat gggacgactc actttactta tgcaacttat
    87721 ggtcagggaa ctttaccaaa agaattccaa gaagctagcc aagaaagtcg tgaacgtagt
    87781 gatccgctaa atagttatct ccttttgtca ggctccttga cgaaagaaaa gcttgccgat
    87841 aaattaggag atttgggtta taaagcaagt gctgaccgaa agataccgcc ctattttctt
    87901 gcttttcgaa tattactaaa tccccttatt ttaattagtt tagcaatatt tggcttatct
    87961 ttctttgctt tagtgattat cactcggatt aaggaaatga gagcagcagg tataaaactc
    88021 ttttctggtc agactctctt atccatcatg ggggattctt tatctactga tatcaagtgg
    88081 ctccttctat cagccctcct ttccttccta ggtgggggag tcgttctttt tagtcaaggt
    88141 ttgttttatc ctatcttgtt agccacctat ggttttggga ttagtttcta tctgttgttt
    88201 ttattggcga tttcaatttt actaatgctt ctttatctaa tgagtttgag ttacaaagca
    88261 ttagttcccg ttattaaggg gagattaccc cttaaacgcc tgatgatttt aaccctattg
    88321 tgtcagttgg ttgctgtctt tacagtagga tacgctgtta agacaggttt gacgtcttac
    88381 caacgattga aagaacttga aatttcaaaa caagcatggc aggatagagc agactattat
    88441 caaatttctt ttggcttagg tgatagagga aaagatacag aaaatcagag caagtgatat
    88501 gcctttgcca aggaagcaat cgaagaagaa caagctcttt atgtaaagga taatctgctc
    88561 cattttgcca atccacaagg aaaaaatgaa cagggagaga cactggatac ctatagtcca
    88621 gatgctaata cgctctatgt tagtcccagt tatttggaca aggaaaaggt cgtggtagat
    88681 gctgagacca aacagaagtt agcccatctt caaaaaggtg agtttatcct cttgctccca
    88741 gaacatttgc gctctcgaga agcagaactt aagaaagttt ttgaagaaag attgagttat
    88801 tatggaaaat ctggtgagga ggcaagtgct cctttggatt atgagatgaa agcgcacgtt
    88861 agttatcttt caatgggaga aaagcggttt gtttataata acggtgagaa tcccgtatcc
    88921 actcagtatt tgactgatcc gattttagtg gtattcacgc cgacttctac aggtgatagt
    88981 tttatatcct tatctagttg gtctatcaat gctggaaaac aactctttat caaaggatat
    89041 gagagtgggc tagaactctt gaagaaagct ggaatttatg agcaagtatc ctatcttaaa
    89101 gaaggaagaa gtgtttatct aactcgttat aatgaagttc aaactgaaac agcaacttta
    89161 atcttaggag ctattgttgg aatagccagt tccttgttac tcttttattc tgtcaatctt
    89221 ctatatttcg agcaattccg ccgagatatc ttgattaaac gaatttcagg tttacgattt
    89281 tttgaaacac atgctcagta tatggttagc caatttgcca gttttgtatt tggtgctagt
    89341 ctctttattt taagcagtcg agacttggtg attggcttgc tcactttatt ggtctttcta
    89401 gctagtgcag ttttgacgct ttaccgtcaa gcgcagaaag aatctcgtgt ttctatgaca
    89461 attatgaaag gaaaatagga tgattgaact aaagaatata tctaaaaaat ttggaagccg
    89521 tcagctattt tcagatatga atcttcattt tgaaggtggg aaaatttatg ccttaatcgg
    89581 tacaagtggc tgtggtaaga caacactctt gaatatgatt ggacgattag agccatatga
    89641 caaagggcaa atcatatatg atggcacttc tcttaaggac attaagcctt ctgttttctt
    89701 tagagattac ttaggatact tatttcaaga ttttggctta attgaaagcc aaaccgtcaa
    89761 agagaatctc aatctgggtt tagttggtaa aaagttgaag gaaaaagaga aaatctcttt
    89821 gatgaaacaa gctctaaacc gtgtaaacct ctcttatttg gatttgaagc aacctatatt
    89881 tgagttatca ggaggagaag cacaacgtgt tgcactagcg aagataattt taaaggatcc
    89941 acctttgatc ctcgcagatg aaccaaccgc ttccttagac cccaaaaact ctgaggaatt
    90001 actttccatc ctagaatctt taaaaaatcc gaatcggacc attattattg cgacccataa
    90061 tcctctgatt tgggagcaag tggatcaggt cattcgagtt accgatttat cacatagatg
    90121 atatggtaag attcagttag aagaaagagt cacaaacaca ctttgtggct tttttatttc
    90181 cataaaaatg gtaaaatagt aggagtagaa atggagttcg agacatgaaa gtaatagatc
    90241 aatttaaaaa taagaaagtc cttgttttag gtttggccaa gtctggtgaa tctgcagctc
    90301 gtttgttgga caagctaggt gccattgtga cagtaaatga tgggaaacct ttcgaggaca
    90361 atccagctgc ccaaagtttg ctggaagaag ggatcaaggt cattacaggt ggccatcctt
    90421 tggaactctt ggatgaagag tttgccctta tggtgaaaaa tccaggtatc ccctacaaca
    90481 atcccatgat tgaaaaggct ttggccaagg gaattccagt cttgactgag gtggaattgg
    90541 cttatttgat ttcagaagca ccgattattg gtatcacagg atcgaacggt aagacaacca
    90601 caacgactat gattggggaa gttttgactg ctgctgggga acatggtctt ttatcaggga
    90661 atatcggcta tccagctagt caggttgctc aaatagcatc agataaggac acgcttgtta
    90721 tggaactttc ttctttccaa ctcatgggtg ttcaagaatt ccatccagag attgcggtta
    90781 ttaccaacct catgccaact catatcgact accatgggtc attttcggaa tatgtagcag
    90841 ccaagtggaa tatccagaac aagatgacag cagctgattt ccttgtcttg aactttaatc
    90901 aagacttggc aaaagacttg gcttccaaga cagaagccac tgttgtacca ttttcaacac
    90961 ttgaaaaggt tgatggagct tatctggaag atggtcaact ctacttccgt ggtgaagtag
    91021 tcatggcagc gaatgaaatc ggtgttccag gtagccacaa tgtggaaaat gcccttgcga
    91081 ctattgctgt agccaagctt cgtggtgtgg acaatcaaac catcaaggaa actctttcag
    91141 ccttcggtgg tgtcaaacac cgtctccagt ttgtggatga catcaagggt gttaaattct
    91201 ataacgacag taaatcaact aatatcttgg ctactcaaaa agccttgtca ggatttgaca
    91261 acagcaaggt cgtcttgatt gcaggtggtt tggaccgtgg caatgagttt gacgaattgg
    91321 tgccagacat tactggactc aagaagatgg tcatcctggg tcaatctgca gaacgtgtca
    91381 aacgggcagc agacaaggct ggtgtcgctt atgtggaggc gacagatatt gcagatgcga
    91441 cccgcaaggc ctatgagctt gcgactcaag gagatgtggt tcttcttagt cctgccaatg
    91501 ccagctggga tatgtatgct aactttgaag tacgtggcga cctctttatc gacacagtag
    91561 cggagttaaa agaataaaat atgaaaaaaa ttgtctttac aggtgggggg acggttggac
    91621 acgttaccct caatcttttg ttaatgccca agttcatcga agatggttgg gaagtccact
    91681 atatcgggga caagcgtggt atcgaacacc aagaaatcct taagtcaggt ttggatgtca
    91741 ctttccactc cattgcgact gggaaattgc gtcgctattt ctcttggcaa aatatgctgg
    91801 acgtcttcaa agttggctgg ggaatcgtcc aatcgctctt tatcatgttg cgacttcgtc
    91861 cacagaccct tttttcaaag ggaggctttg tctcagtacc gcctgttatc gctgcgcgtg
    91921 tgtcaggagt gcctgtcttt attcacgaat ctgacctgtc tatgggcttg gccaataaaa
    91981 tcgcctataa atttgcgact aagatgtatt caacctttga acaagcttcg agtttggcta
    92041 aggtcgagca tgtgggagcg gtgaccaagg tttcggacaa aaacactcca gaaccagatg
    92101 aattggtgga tattcaaacc cactttaatc ccaaattgcc aactgtattg tttgtcggcg
    92161 gttctgcagg cgctcgtgtc tttaaccaat tggtgacaga ccataagaaa gaactaacag
    92221 agcgctacaa tattatcaat ttaactggag attctagcct gaatgagttg aggcaaaatc
    92281 tttttcgtgt tgactatgtg accgatctct atcaaccctt gatggaattg gctgatattg
    92341 ttgtgacacg aggtggtgcc aatacgattt ttgagctctt ggcgatagca aaattgcatg
    92401 tcattgtgcc gcttggtcgt gaagctagtc gtggtgacca gattgaaaat gcagcttact
    92461 ttgtaaaaaa aggctatgca gaagaccttc aagaaagcga tttgaccttg gatagtttgg
    92521 aagagaagct ttctcactta ctaagtcaca aggaagatta ccaagctaag atgaaagctt
    92581 ctaaggaatt gaaatctcta gcagattttt atcaattgtt gaaaaaagat ttatcataag
    92641 gaaagtaaat gtcaaaagat aagaaaaatg aggacaaaga aatcctcgaa gaattgaaag
    92701 agttatcaga atggcagaaa cgaaaccaag aatatctaaa aaagaaggct gaagaagagg
    92761 cggctctagc tgaggagaag gaaaaggaaa gacaagctcg aatgggagaa gaatctgaga
    92821 agtcagagga taaacaggac caggagagtg aaacagacca ggaagattca gaatcagcta
    92881 aggaagagtc tgaagaaaaa gtggcatcct cagaggctga caaagagaaa gaagaaaaag
    92941 aagagataga agaatcagag tctaaagaga aggaggaaca ggataaaaag cttgctaaaa
    93001 aggctataaa ggaaaaacca gccaaagcaa agattcctgg tatccatatc ttgcgagcct
    93061 tcacgatttt atttccaagt ctgcttttat tgattgtctc tgcctacttg ctcagtcctt
    93121 atgcgaccat gaaagatatt cgtgttgagg gaacggtgca aactacagct gatgatattc
    93181 gacaggcttc aggcattcag gattcggatt atacgattaa ccttctgcta gacaaggcaa
    93241 aatatgaaaa gcagattaag tctaactatt gggttgaatc agctcaactt gtctatcaat
    93301 ttccaactaa gttcactatt aaggtcaagg aatatgatat tgtggcctac tatatttctg
    93361 gtgaaaatca ttatcctatt ctttccagtg gtcagcttga gactagttct gtgagcctga
    93421 acagtttacc agaaacttat ttatcagttc tctttaatga tagtgaacaa atcaaggctt
    93481 ttgtctcaga acttgctcaa attagcccag aactcaaggc ggctatccaa aaggtggaat
    93541 tagccccaag caaggtgaca tccgatttaa ttcgattgac catgaatgat tcggacgaag
    93601 tcttggttcc tctatctgaa atgagtaaga aactgccata ttacagtaag attaagcctc
    93661 aattgtcaga accgagtgtg gtcgacatgg aagctggaat ctacagctac actgtggcgg
    93721 ataaattaat tatggaggct gaggaaaaag ccaaacaaga ggccaaggaa gctgagaaaa
    93781 aacaggaaga agaacagaaa cgtttagaag aagaacagaa aaaacaagag gaagagagca
    93841 atcgaaacca aacgacccag cgctcatcgc gtcgctaggt ttaccttttc tcttatagtt
    93901 ctttagtgac catgttttta cttgacaagt gctagtagaa ataatagaat agtaaaaaac
    93961 ctttaaagca gtccagagag gcagctaagg ttagacggtg aaagggtgga gactacccat
    94021 ttttcgtgga accttgctgt tggcaggttc cttttttcgt ggcttctgtt ggccagactc
    94081 tctcactagt aaaggtaaaa ggagaaacct atgcgagaac atcgtccaat cattgctctt
    94141 gattttccta gttttgaggc ggtcaaggaa tttttagctc ttttcccagc agaagaaagc
    94201 ctttatctca aggtagggat ggagctttat tacgcagcgg ggcctgagat tgtgtcctac
    94261 ttaaaaggtt tgggtcatag tgtctttttg gatctcaaac ttcatgacat tcctaataca
    94321 gtcaagtcag ccatgaaggt cttgtctcag cttggtgtcg atatgactaa tgtccatgcg
    94381 gctggtggtg tagagatgat gaaggcggcg cgtgaaggtc ttgggagtca agccaaattg
    94441 atcgctgtaa cgcagctgac atcaacgtca gaagcccaga tgcaggagtt tcaaaatatc
    94501 caaaccagtc tgcaagagtc tgtgattcac tatgccaaga agacagctga agctggcttg
    94561 gatggtgttg tttgctcggc tcaggaagta caagtcatca agcaggctac caatccagat
    94621 tttatctgtc tgacaccagg gattcgtcca gctggtgttg cagttggaga tcaaaaacga
    94681 gtcatgacac ctgctgatgc ctatcaaatc ggcagtgact atatcgtagt gggacgtccc
    94741 attacccaag ctgaggatcc tgttgcagct tatcatgcca tcaaggatga atggacacag
    94801 gactggaatt aaagaactag attagaaaaa taaaaggaga ataccatgac acttgctaaa
    94861 gatatcgcta gccacctctt gaaaatccaa gccgtttacc tcaaaccaga ggaacccttc
    94921 acttgggcat ctggtatcaa gtcaccgatt tacactgata atcgtgtgac actagcctat
    94981 ccagaaactc gtaccctaat tgaaaatggt tttgtggaag ctatcaaaga agcctttcct
    95041 gaagtagaag tgattgcagg aactgcaaca gcagggattc cacacggagc cattattgct
    95101 gataagatgg acttgccttt tgcctacatc cgtagcaaac caaaagacca cggagctggt
    95161 aatcaaatcg aaggtcgcgt agctcaaggt caaaaaatgg tagtggttga agaccttatt
    95221 tcaacgggtg gttcagttct tgaagctgta gcagcagcca agcgagaagg agcagatgta
    95281 cttggagttg tagcgatttt cagctaccaa ttgccaaaag cagataagaa ctttgcagat
    95341 gctggtgtta aacttgtgac gctttcaaac tatagcgagc ttatccatct agcccaagaa
    95401 gaaggttaca tcacgccaga gggccttgat cttctaaaac gctttaaaga agaccaagaa
    95461 aattggcaag aaggttaggt cagtaagata aagagagacg aggctaccga gtctctttta
    95521 ccattttatt taaaatatga caatatttta aataaaataa ttgacaacgc tttcttttat
    95581 tgatataatg aaaatgtaat atgtatcaaa ttgatcaatc aactatcttg tttatcactt
    95641 cttaagagga cgatgtcatg aaaagaagaa aaatatattc cttttttgcg tagttacaat
    95701 tgcatctagt ttgtttctcc ctacagtttt agctagacag attggaaatt atgatttaac
    95761 gttgccgcgt tggggttcgg atacaactag tgagcttgag aaagaaaacg cctctgctgg
    95821 aattaataat agtgacagca ctggtggcgg taaaaggtta agtacctcta ttcgtagcgc
    95881 ctatagtggg tcagatatta ccccggtata ttcattgggg tctggctcta ggattgtcat
    95941 gtactataat ggaggtggtg acaattatat tggttctggt actagattag ctatggcgcc
    96001 acaatttgga aatcatgtaa gaattcatac ttcaggttct tggagtccag attcttatta
    96061 acttacttgt cagagtaagc cttaaagatg gttgattgtg ggtgtagcat gaaaaaagaa
    96121 tgctacaccc tatttttatt ataaggagga gtaaggatgg aatttttcat ttgtaatctt
    96181 gtacgagtcg ttcaatcacc tcgattttat atgtctttat ttttgaccct tctttgcatg
    96241 agtttaggaa atttccttgc tttcaatggt atttataaaa ttgaaggttt atcgattttt
    96301 tttgccgctt cttctattcg aggattttca ccgattagcc tagtagctgc acttatctgt
    96361 acactgccct attctagtca gataatagag gatgctgaga gtcattttct aacagcacaa
    96421 ttgtgccgaa tttctaaaaa gaggtatcta gctattgtag gtagtactgc aattatttct
    96481 tcttttctag tcttttttct cccctattta ttattattag gaattaatct tttagtgact
    96541 ccttatcagg aaatttatat tggagattat agtggtgcct taaaagaatt atttgattct
    96601 aatcagttgc tctatagtct tgtgacgact ctctggtatg gagtttgggg cgctgtgttc
    96661 tctatttttg gactagctag tgctttgcta gtgaagaaaa aaataggagc tattttcatc
    96721 ccagttgcct atatgatggt tggtggtatt tttttggcta ttttagggct atcttactta
    96781 gaacctgtga caacattagc tttgggatat cagaaagata tcagtctttc cttagttagt
    96841 gggcatcttg cttttatttt atttgttagt tgtttggttg tttatggtac attttttcta
    96901 cattcagagg actatgtata atgaaacaat ttgttcaatt ttataaaaaa gatttcttag
    96961 cagtattggt ttattttata ttactgctat cctgtgtttt atctagtaca gtatatttat
    97021 tgcgctgtcg ccaatattca atccatccaa atgtattaga atggatctta gttttacttc
    97081 aagatatgac gactggagta tattgctttc cgttcacata tatattgttc tttttttatt
    97141 tgatgaataa ctattttaat aggttggagt gtcgcattcg tctgaaatca attaagcact
    97201 ttaccagttt tagtttcaaa ttagcagctc ttagtacggg gatttggacg gcgattttat
    97261 ttttattgat ttttctaatt gcatttagta atggttttag cttctctttg gagataaagg
    97321 aggttgattt tttaagagaa ttttatggca taagtattgc aaacaatgct agtttcttta
    97381 taggattttt tttctcttat atagcatact atttcttttt atccttactt actattagca
    97441 gtttttcttg gtttaaaaaa tcaaacatga gcttagtatt tctgtttact tttttatttg
    97501 tagaatcctt attctggatt tatcagttga acaatgggat aattggatta ttgccaattt
    97561 ttcagtatat ggtaaattcc aatccgtatg cattgattta ttggcttgca ttactatcta
    97621 tcataattcc attgactgta ttttctgttc atagaaactg gaggagagtg taaaagttgg
    97681 aaatgggaaa gttaagtagt cacatgtgga ggttgaatca gataatctat accaagtact
    97741 tttggggtta tgttcttttt tggatattga tttgtttagg attatggtat tggttagaag
    97801 gaaatgatag acttgttata gaaattttaa aagggcctaa tctgagtcaa aactcttttt
    97861 tagtcttatc tatatggttg cttcattggt ttattattca tacatttttt ctagcagttg
    97921 tatatcgtag aagagcatcc gatttctttc tggaagtgat tcgattttct tctattaagc
    97981 tctggattag gtatcagatt tggacctgtt ttctttatgg acttatttta atcatggtaa
    98041 aagttctagt gattcaattt atgttacagt taccaaactg ggatatagga gttttgttta
    98101 tagttgattc tttgaatgct tgtgtgctat ccttgctttg ctttatgtta tacgcactag
    98161 gagcgaatgt acaaatgaac tttgcttgcg ttagtttctt tttactcatg attgtgtttg
    98221 gtggtctatt tgtaggaaat cgaactaatt atctatttta tattttgaat cgagggaatg
    98281 gagatatagg acgagattta tttcttcagt tgctattttt agtctttctt tttaaaagca
    98341 ttttctattt cactcgtcaa aagaggaggt ttatagaatg aatgaaataa ttacattaaa
    98401 aaatattgag ttgaaattaa aaaaaacatg tgtttttcaa aaccttaatt ttagttgtaa
    98461 acagggggaa attataggaa ttactggtgc gaatggctca ggtaaaagtg tattgtttaa
    98521 attaatagct ggtttatata gtccgtctta tggagaagtg ttaatcaatg gggaaaatat
    98581 tgttcctgag agaaaaattc cagctaattt gggagctttg attgaagaac ctggttttat
    98641 aaattattat agtggcttta agaatttaca atatttggca agcatacgag gagtagttgg
    98701 taatcaggaa atcaatgata cactgaaaat agttggtcta tatgagcaaa aagaccagaa
    98761 agttaaaact tattcgctag gtatgaggaa aaagctaggg attgctcaag caattatgga
    98821 gaatccctct attcttttac tagatgaacc tatgaatgcc ttggataaat caagtgtaga
    98881 aaatatgaga acattgttta gaaagctctc tagtgaaaaa gggacaacaa ttttgattgc
    98941 tagtcatagt gaagaggata ttcgtatctt atgtgataaa gtatatgcaa tagaagataa
    99001 agtatgtaca ctgtgttcag attgaacatc ttagatagac tcaggatgtt ataggtaaaa
    99061 tcttaaaaag ggattggagc ttaaaatcca gttcctttta agagttaatg actaatcaac
    99121 ttttccacct tcaacaacca ggtcatctgc tttagcagtg tcaccgtagg ttgggtgaag
    99181 tgttttttca taggccttgt ggaagaagtt ttccttgcct aatttttcaa tatctttatt
    99241 gatgaagtct agcaattctt ggttgccttt ttgaactgct gccgcaatgg tatcgggatc
    99301 accgagggaa gtaattccta cttcaaatcc tttattttca agcgcccaag ctagaacttc
    99361 cgtattatca gttgaaaagg catctccacg tccgtcaaga agagcttggt aagagtcact
    99421 gtattggtcg tatttttgga gtttgatttc tggatgattc ttttcaaaat aagtctcagc
    99481 agtcgttcct tttgtgacaa ttaaggtttt accttcaagt tgtttgacgt ctgtaatgag
    99541 accagtctta ggtgatacga cacccagaga aactttcata tatggaaggg caaaatcaac
    99601 ttgtttctta cgttcgtcag ttactgtaaa gttagcaaga ataatatcta ccttgtttga
    99661 aatcaagtat tccgcacggt tggcagcatc gactgaaatg tatttaacct tgacaccaag
    99721 gttttgagct agttggttcc ctagttcaat atcgtagcct tggtaagaac catcattgtc
    99781 aacgtagcca aacagttttt tatctccaaa cacggcgatt cgcagttcac cgcttttttt
    99841 gatttcatcg atagtgcgag ctttggcagt tgtttttcca gaggatgaac cagcgtttcc
    99901 acctgagcta caagcagtga taaagataag ggcaaaggca agtactaaaa cagttaagag
    99961 tggtttgaat agtttcataa gaatctcctt tatagatatg agccgaattg gctaaagtca
   100021 aagacgttta aaaattcctg ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct
   100081 gttccttctt cagcgatttt cccttggtcg aggaagataa tccggtcagc aatggcttgg
   100141 gcaaactgca tttcgtgggt tactaaaatc atggtacggc cttcttgggc caaatcattg
   100201 ataagttcca gcacctcacg caccatttct ggatccagcg aagcagtcac ctcgtcaaaa
   100261 aggatgattt ctggatgcat taggagggca cggacaattg caacacgttg cttctgtcca
   100321 ccagataatt gacgggcaaa gctatgttgt ttatccagca aaccgacacg atctagtaat
   100381 tgcaaagctt cttccgttac ttctttcttg tcccttcctt gagttttgat agggcctagg
   100441 atgaggtttt gtaagacatc cagatgggga aagagttcat aactttgaaa gaccatgcca
   100501 atcttttggc gaactaggtg aaaatctttt ttattttcaa cgatagactg accatccaga
   100561 aaaatatctc caccttgaat actttctaag ccgttgaggc aacgaaggag ggtacttttc
   100621 ccacaaccag atggccctag gatgacaaca acttcccttt tttgatttct agagaaagtc
   100681 ctttgaggat gggattgtct ccgaaggatt tttttagttc cttgatttct aagatagttt
   100741 cagacattta gtttctccaa tgtttttcta agtgagtgga tagtttggaa atagggtagc
   100801 aaactgcgaa atataagact agaatggttc cataaatcca aaatgaagca gttgggatgg
   100861 tcaggcgatt gctatcgatg atttgttgtc caactttggt cacttccaca accccaatca
   100921 aaacaactaa tgaagtggtt ttaatcatcc gagtgacaag attgatagcc tgcggtagca
   100981 gtcttcttaa gacttgtggg atgatgatgt ggtagtaaag ttgaacatta gtcaagccga
   101041 gtgcctgtcc actttcaaac tgatgtttag ggagagaagt gatagctcca cgtaccaagt
   101101 ctcccatttc agctgttccc cagagggtaa aaacgataat agctgaagtc tcacctgaga
   101161 tattgatatt aaagtttcga gccaagccaa agtaaacgat gaagagtagc accagctggg
   101221 gcatgatacg gataaattcc agatacaatc gtgttaaaaa tcgtatgatt ctagaatggg
   101281 aggtcatgat gattcccatg actgttctga acatcatgga taagaggaca gacaggatgg
   101341 atatctcaat cgtaacgccc aatccctgta agattctcag gagattattt ccctgaaaga
   101401 gtacttggat tcccgaatcc tgcatggcgg agcctccttt ctatccagct aaagaccagt
   101461 gagatgggta gcagcatgat cagataagca actaccaaca tagctagcgc aatgtctgtc
   101521 tcatagtaga gaccaatcaa atccttggcg acatacatga ggtcggccaa agccactgct
   101581 gagaaaacag aggtttcctt gataaggaaa atgacattgg cactaaagga ggggagtgcc
   101641 accgctgttg cttgcggaag aaccacatag cgaaagacct gtagaggtgt cagaccaata
   101701 gcgaggccaa tctcctgctg ggtttgactg atggcttcca gcccacttcg gaaagattct
   101761 gccatatagg agcctcctaa aaagacaagc ccaagcgttg cacagacttc tgaagatagg
   101821 acaatcccga ttcggggaag accgaagtag agaaagaaga gttgaatcaa aaggggcgta
   101881 ttacgtgaca attcaatgta ggctgtcgct acttgcgcca aaacagggat tcgataatgt
   101941 cggatgatac taacgattaa accgagcaga aaggatccca aaattcccca aactgcaata
   102001 tgcaaggtca gaaagaatgc cttttgatat agtggtagat attgttcaac aatggaccaa
   102061 tccaaaaata gaacctccca tctagaaata atacagttat tgtagcactt aaaatcttct
   102121 ttggataata tctatttttt attgccgtta taaggatttt ttaccataga cataaaattt
   102181 ctgaaatttc caaacaaaat atttgaaaag ttttgaaaaa gagttaagat atttttgtaa
   102241 tatacaaagt gaacgcttac ttattaagga gggcatttta tgtcatacaa aacaagcaat
   102301 gcagaaggtc atgtagattt catcaatacc tatgatttgg agccaatggc gcaacaagtt
   102361 attcctaaag cagcatttgg ctatatcgct agtggggcgg aagatacttt cacttctttc
   102421 cagtgatttt agcgtcaggt tctttttagt ttttaaagat tatccgtgaa tttcttgctt
   102481 atttatgata aaatgggggt atcgcaaaaa atgactcatc gtattcaatt ttgagtaaaa
   102541 ctaggaggat cccatgtcta cagaacatat ggaagaacta aatgaccagc agatcgttcg
   102601 ccgtgaaaaa atggctgcgc tctgcgaaca aggaatcgat cctttcggaa aacgttttga
   102661 acgtactgca aattcacaag aattaaaaga taaatatgcc aacctcgata aagaacaatt
   102721 acacgataaa aacgaaacag ctactatcgc aggacgcttg gtaaccaaac gtggtaaagg
   102781 aaaagttggt tttgcccacc ttcaagaccg cgaaggccag attcagatct acgttcgtaa
   102841 ggatgctgtc ggtgaagaaa actacgaaat cttcaaaaaa gcagaccttg gtgacttcct
   102901 tggtgtcgaa ggtgaagtga tgcgtacgga tatgggagaa ctctctatca aggcaaccca
   102961 catcacacac ttgtctaagg ctcttcgtcc tcttcctgag aaattccatg gtttgacaga
   103021 cgttgaaaca atttaccgta aacgttacct tgacttgatt tctaaccgtg aaagctttga
   103081 acgctttgtc actcgttcaa aaatcatctc tgaaatccgt cgttaccttg accaaaaagg
   103141 attccttgaa gtggaaacac ctgttcttca taatgaagcc ggtggtgctg ctgcccgtcc
   103201 atttatcacc caccacaatg cccaaaacat tgacatggtg cttcgtatcg cgactgagct
   103261 tcacttaaaa cgccttatcg tgggtggtat ggaacgtgtc tatgaaattg gccgtatctt
   103321 ccgtaacgaa ggaatggacg ctactcataa ccctgagttt acttctatcg aagtttacca
   103381 agcttatgca gacttccaag acatcatgga cttgacggaa ggcattatcc aacacgctgc
   103441 taaatcagtt aagggcgatg gcccagtcaa ctaccaaggt actgaaatca agattaacga
   103501 accatttaag cgtgttcata tggtggatgc tatcagagaa attactggtg tcgatttctg
   103561 gcaagacatg actttagaag aagctaaagt tatcgctgct gagaagaaag ttccagttga
   103621 gaaacactac actgaggttg gtcacatcat caatgccttc tttgaagagt ttgttgaaga
   103681 aactttaatc caaccaacct ttgtctatgg acatccagta gctgtatctc cactcgctaa
   103741 gaaaaatcct gaagaccaac gctttactga ccgtttcgag ctctttatca tgactaagga
   103801 gtacggtaat gcctttactg aactcaacga cccaatcgac caacttagcc gttttgaagc
   103861 ccaagctaaa gccaaagaac ttggtgatga tgaagcgaca ggaatcgact atgactacat
   103921 tgaagctctt gaatacggta tgccaccaac aggtggtttg ggaatcggta tcgaccgtct
   103981 ctgcatgctc ctcactgata caacaactat ccgtgatgta ttgctcttcc caacaatgaa
   104041 ataaattctt atcctctggc tcttaccaga ggattttttg attcaaaaag agactgaatt
   104101 taaggagaaa atgaagtgta gtatattgaa gttgaaatag tacactttga tttctaagac
   104161 attgttagaa attggtttaa attccctaag caatttgtgc atgttttatt tcattttacg
   104221 atagtacgct gaaactgttc aaaaagtact agaaattgac ttggattccc caattgattt
   104281 gttcagattc actataaata aaaaattaat aagtgggata ggaagttagc gtcaactagg
   104341 atagtatctt gcttaaacag tatatatggg actgatataa gtccataggt cctattagag
   104401 gatgttctgg tgtcttattc acttgttttt tatagtatta gtagatagaa tcagcaaata
   104461 aaaaagtagt tcaaatgcct ggcagcaaaa aatctcaacg attcacttaa tatagactaa
   104521 ggtttagagt ttaaggaaag tagggctagt atattgtatg aaaaaataag atggttttta
   104581 agcaaaactc ttgaaaatga ttgaaaaaag agttattata gttgtatagt aaaaagcaaa
   104641 cgcttactta atcgaggagg acagtttatg tcatacaaaa caagcaatgc agaaggtcat
   104701 gtagacttca tcaataccta tgatttggag ccaatggcgc aacaagttat tcctaaagca
   104761 gcatttggct atatcgctag tggggcggaa gatactttca ctttaagaga gaatatccgt
   104821 gcctttaacc acaagctcat cgttcctcat acactttgca atgtagaaaa tccaagtaca
   104881 gagattgaat ttgcaggtga aaaactatct tcaccaatca ttatggcgcc tgttgcggcc
   104941 cataaattag cgaatgaaca gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt
   105001 tctctttata caaccagttc ttactctact gttgaccttc cagagatttc tgaagccctt
   105061 caagggacac ctcattggtt tcaattttac tttagtaagg atgacggtat caaccgccac
   105121 atcatggacc gtgtgaaggc tgaaggttat aaagcgattg tcttgacggc agatgctact
   105181 gtagggggga atcgtgaagt ggataagcgt aatggttttg tcttcccagt tggcatgccg
   105241 attgttgaag aatacctgcc agaaggtgct ggtaaatcaa tggactttgt ttacaaatca
   105301 gctaaacaac gcttgtctcc acgcgatgta gaatttatcg ctgaatactc tggtcttcct
   105361 gtgtatgtca agggaccaca atgccgtgag gacgttgaac gttcgcttgc tgcaggagct
   105421 tctggtatct gggtaaccaa ccacggtggt cgtcaaatcg acggtggacc agctgccttt
   105481 gactcgcttc aagaagtggc agaagcagtt gatagacgtg tgccgattgt ctttgactct
   105541 ggtgttcgtc gtggtcaaca cgtctttaaa gccttggctt caggagcaga cttggtagct
   105601 attggtcgcc ctgttattta tggcttggct ctcggtggta gtgtcggtgt gcgtcaagtc
   105661 tttgaacact tgaatgcgga attgaagaca gttatgcaat tgtctggagc tcagaccatt
   105721 gaagatgtca aacactttaa gctccgtcac aatccataca acccaacctt cccagttgac
   105781 cctcgtgact taaaattgta ttgataaaac agattgcctc cactgaatgt ggaggttttt
   105841 cttcgtgtat tggaagaata aattgctatc gaaaactata gtaaaatgaa ataagaatag
   105901 gacaaatcaa tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac
   105961 tattctagtt tcaatctact atataaagat atttttcggt caaatatctt gctagggctt
   106021 tcattttttg ctatactggt tcagtaatta aataatagag acatttgggg tgctttaagc
   106081 tgagatgata cccattgaac ctgatacagt taagactggc gaagggaaat gtgaaacgtt
   106141 ttttcgtatg gcgaaatgaa cgatctaatc ttgtaagtca actctaattc ttgattgtaa
   106201 ttggagtttt ttgtttatat aaactggata ggcttgttta gttagctctc tgcaaatgct
   106261 ctcgatgtgc tttaaaagga tcaagtggaa ttacgatttt gcttgatatt tcttggtgtt
   106321 ttattaatta ctaacaagta aagagaggag aagtaaatat ggaaacacaa gactatgcat
   106381 ttcagccagg tttgactgtt ggagaattat taaaaagcag tcagaaggat tggcaggctg
   106441 caatcaatca tcgttttgtt aaggaacttt ttgcggggac aattgagaat aaggtcttaa
   106501 aggactatct gattcaagat tatcacttct ttgatgcctt cttatccatg ctgggtgcct
   106561 gcgtagctca cgcagataaa cttgaatcca agcttcgttt tgccaagcaa ctaggctttc
   106621 ttgaagcaga tgaagatggt tatttccaaa aggcttttaa agagttaaaa gtagcagaga
   106681 atgactatct agaagtgact ttgcaccctg taacaaaagc ctttcaggat ctaatgtatt
   106741 cggcagtggc ttcatcagac tatgcccatc ttttggttat gctggtcatt gcagaaggtc
   106801 tctatttaga ctggggttct aaagatttgg ctctacctga agtctatatt cattcggaat
   106861 ggatcaatct ccacagaggt cctttctttg cagagtgggt tcaatttctg gttgacgaac
   106921 tcaatcgtgt cggtaaaaat cgagaagatt tgacagaact tcagcaacgc tggaatcaag
   106981 cagtcgcttt agaattagct ttttttgata ttggttacga tgtctagaga aggctcatga
   107041 tatttacaaa tttgatgagg taatactctt cgaaaatctc ttcaaaccac gtcagtttca
   107101 ccttgccgta ggtatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
   107161 ttgagctgac ttcgtcagtc ttatctacag gttcaaagca gtgttttgag caatctgcgg
   107221 ttagcttcct agtttgctct ttgattttca ttgagtataa atcattcaac gtaaatgaaa
   107281 aaaatttctt aacgaaagat agagataaat cgaaatcagt agatcgtata aagtgaaaag
   107341 gaaggatttc aatatgacaa gtttaaaatt attaaaaaaa aaagcaccat tggtcatttg
   107401 tataaccaat gatgtagtaa aaaatttcac agcaaatgga ttagtagcac tgggcgcctc
   107461 accagccatg agtgagtttc cagcagattt agaggatttg ttaaagtatg ctggtggttt
   107521 attaataaac ataggaacat tgacagatga aaattggaaa ttataccaag ctgctctgaa
   107581 aattgcggag aaatataatg tcccagcagt tttagatcct gtagcctgtg gagcaggaga
   107641 atatagaaaa aaagtagcag atgatctaat caacaattat aaactagcag cgattagagg
   107701 aaatgctggc gagattgcct ctttagtagg aatggatgtg gcatctaaag gagtagatag
   107761 tgcgggcgta gataatattg acgaaattgc tctagcagca aatgagaagt tcaatattcc
   107821 aatagtagta acaggtgaag tggatgccat tgctgttaat ggagaagtgg taacgattca
   107881 taatggtagt gctatgatgc cgaaagtcat tgggacagga tgcttattag gagctgtagt
   107941 agcaagcttt atcggacttg aaaaaggtca agaattgaaa tcattagaaa cagcaatgtt
   108001 ggtttacaat atcgctggag aaatggcgga aaaacgtcca aatggacatc ttcctggaac
   108061 atttaaagtt gaatttataa atgccttata tgaaattaca gatgaagatg tcaagaaatt
   108121 caaaagagtg aagtaagatg tttcataaag aattactaaa actatatttt atttgtggaa
   108181 cgactacttg ccaaggaaaa gatctatata cagtcgttga ggaagcctta aaaggtggta
   108241 taaccttatt tcaatttcga gaaaaaggtg agggtgcttt agaaggctta gaaaaacttg
   108301 agctagctat ccaaattaaa gaactttgta aaaaatacaa tgttccattt atcgttaatg
   108361 acgatataga tttagcaatg gaaattgacg ccgatggcgt acatgtaggt caagatgata
   108421 ttggtgttga tgaaattaga aaattgatgc cagataaaat aattggtctt tctataaaaa
   108481 acgaggaaga atttcaacaa tcaaaagttg aatatgtaga ttatgtaggt gttgggcctg
   108541 tatttgatac ccagtcaaaa gatgatgctg gtggtgctat aggttatgaa ggtcttgaat
   108601 tgatgagaaa actattgcca caaatgcctt tagttgcaat tggtgggata cagacgaaac
   108661 atattaaaga cattataaag accaatgttg acggcgtttc aatcatttcg gcaatatcgt
   108721 atgcaaaaaa tatagaaaaa actgttcggg aaatgagtga acaatagata tctatccttg
   108781 gattctaagt aagtaggatt ttcctttttt aaaaagctat gtctagattc agcttgaatg
   108841 gctaattcat caaacaggtc atttgttttt tgcaaaagaa agatctgctg tctttgtgag
   108901 tgcaaggctg tatttccagt tcaatttctt gaactagtat aaaatgtgtg ttataataat
   108961 tacataatta aataataaag gcatttgggg tgctttaggc tgagatgata cccattgaac
   109021 ctgatacagt taagactggc gaagggaaat gtgaaatgtt tttttcgtat gtcgaaaaga
   109081 actgtctaat cttgtaagct gaactctaat tcgtatctgt aattagagtt ttttctttta
   109141 cgaaactgga tgaagatgat atagtagatt gaaataagat gcgaacaaat caattagaaa
   109201 attcaaatta atttctagaa atattttagc attcctgtgt actgttctaa attcaatctg
   109261 ctatacaaag tatttaggtc ggtcttcttg agtgccccac ttttctttta aaaaaggagt
   109321 tttttatgtt gaaaaaatgg cagttaaaag atgttatctt gcttgctttc ttgtctatct
   109381 tttttggtgg ggttttcgtt ggttcaggat atgtgtataa tatgctcagt ctactcttaa
   109441 cacctcttgg tttgcaggcc tttgccaatg aaatcctctt cggtctctgg tgtatggctg
   109501 cgcccattgc tgccatcttt gttccgagag tcggaagtgc aacgattgga gaagtgctag
   109561 ctgcgcttgc tgaagtcctt tatggtagcc aatttggtct aggagctctt ttgtctggct
   109621 tggttcaagg tttgggaagt gaatttggtt ttatcgtaac taagaatcgc tatgaaagtt
   109681 ggctctctct aactgctaat agtattggga ttacgcttgt tagctttgtc tatgaataca
   109741 ttaggttagg ttactacgcc ttttcccttc cgtttgtcct ttccttactt gtggtacgtt
   109801 ttatttctgt ttatttcttc tgtaccatct tggttcgtgc cattgtcaaa ctctatcatc
   109861 agtttgcaac tggaggaaaa gcatagatgg gtctggaact acgagcgatt cagtccccaa
   109921 tcttctctga gccgtttgat tttacttttc atgcgcaagc ctttaccttg ttagttggga
   109981 gtagtggttc aggaaaatcc agcctttttc aagtcattgc ccaagtcagt tctcttccct
   110041 atagtggtca agtcctgata gatgggagcg aggtcagtca gctttctatc atcgcacgtg
   110101 tccagaaggt tggcattctc tttcaaaatc ccaatcatca atttaccatg gagaacttgt
   110161 ttgaggagct gattttcacc ttggagaata tcggctatca ccttcaggaa attgattcta
   110221 aaatagcaga ggttgtccag caatgtcgtt gcgaggcaat cttacaccgt cccattcatc
   110281 acctatcagg tggggaaaag caaaaagcag cgctggctgt cctctttgcc atgaatccta
   110341 gggtctatct cttggatgag cccttcgctt ctattgaccg caagagcaga atcgagatat
   110401 tggagattct aaaagagttg gctcttgatg ggaagacagt tattttgtgc gaccatgatt
   110461 tatctgacta taaagcctat atcgaccata tggttgagct aagagacgga aaactaaggg
   110521 aagtgtttca aatcccttcc tatgagatga cacaggttgc ttcaaaggaa gttgcttcta
   110581 gcccggaact attccatatg aaccgtgtga ctggtgagct tggtaatcgc cccctctttt
   110641 caattgctga tttcacattc tatcaaggga tttcctgtat cctgggtgac aatggtgtcg
   110701 ggaaatcaac cctctttcgc tctattcttc aatttcaaaa gtataagggg cgcattgcat
   110761 ggaaggggac agtcctgaaa aagaaaaaga gtttgtaccg tgatctgacg ggtgttgttc
   110821 aggaagctga gaagcagttt atccgagtaa gtctgcgaga ggagcttcaa ttagatggac
   110881 ctgattctga aagaaatcag cggatttttc aagctttacg atattttgat ttggagcagg
   110941 cagtcgataa gagtccctat caattaagtg gtggtcagca aaaaattctt cagctcctga
   111001 ccatcttgac cagtaaggct tccgtgatct tgctagatga accttttgca ggtttggatg
   111061 atagagcctg ccattatttt tgcaagtgga ttgtggagaa gaggaatcaa ggaagaagtt
   111121 ttctgctcat tagtcatcgt ttagaccctt tgatttctgt ggttgattat tggattgaga
   111181 tgactagtca ggggctcagt catgtgaaag aagtgaccat taccaaacca cttacatctc
   111241 agagtagcaa tacccaaggg gaggtgagat agtatggtca aagtagcaac ccagacaccg
   111301 attatcagtc tcttcttgct gattttatcc ttggaaacat ctttcattcc ttcgattgct
   111361 ctgaatcttt cggtagtcgc attttgtatt ctctttatgc tctattaccg tcgatttaaa
   111421 atgttagctt ggatgatcat acttgccatt ttaccatctt ttgccaacta ctgggcagtt
   111481 cagttacacg gagatgcttc acaggcagtc atgcttggaa cgagggcctt tgtgacagtt
   111541 tgtatcggcc ttgtctttgt ttcctctatt tcactaaaag agcttctctt gtacttggct
   111601 caaaaggggc tatcacgctc ttggtcctat gccttgattg tggtattcaa ttcctttcct
   111661 ctcattcagc aagaaatcaa gtccctcaaa gaagcttgcc tattacgtgg tcaagaactg
   111721 catttttggt cgcccttgat ttacagtaag gttctgatga cagtctttag gtggcgccat
   111781 ctttacctga gagctctgtc tgctcatgga tatgacgaac atgcacagtt gaagaatagc
   111841 tatcggactt tttatattcc taaaaaaaca aaattaatct acctgctttt ctttttattg
   111901 cttcaaacca gtctattttt ataaaggagt tattatggaa tttacagata ttgcgatgga
   111961 attatccaag aaagcttggc aggcttcctt tcatcatccc tttattttac aattacaaga
   112021 ggggaattta gaacctgcca ttttccgcta ttacctgatt caggatgcct actatctgaa
   112081 ggccttctca gaaatctatc atcttttggc tgataagact tcaaaccaag agatgaaaag
   112141 actcttgaaa caaaatgctc agggtttagt ggagggtgag ttatttattc gccaacaatt
   112201 tttcaaggaa ttggaaatca acgaccagga aatggagcaa catccaatcg ctccaacctg
   112261 ttatcattac atttctcata tttataggca atttgcagaa ccgaacttag ccatcgcttt
   112321 tgcaagcttg cttccttgtc cttggttata ccatgatata ggcaaatcac ttaatcttaa
   112381 accatcacca aatcctctct atcaacaatg gattgaaact tatattacgg atgagttaga
   112441 gcaacagatc agagaggagg gagcactggt caatcagctc tatcgagaaa gtgatgagac
   112501 agataagcaa aaaatgctag atgccttcca catcagtgtt catatggaag ccaagttttg
   112561 ggagatggct taccaacacc agacatggaa gagcgattta cagtctttag aaaaaggaga
   112621 agaatagaaa catgagaaag caccaactac aagttcacaa attgaccatt ttatctatga
   112681 tgactgccct tgatgtagtc cttacaccta tctttcggat tgagggaatg gcaccgatgt
   112741 ccagtgtagt caatattcta gcgggaatca tgatgggacc tgtttatgcc ttggccatgg
   112801 ctacagtgac agcctttatc cgtatgacga ctcaagggat tccgccttta gctctcacag
   112861 gagcgacttt tggagccctt ctagcaggtc tcttttataa gtacggtcga aaattttact
   112921 tttctgcctt gggagaaatt gtgggaacag gtattattgg ttctattgtt tcctatcctg
   112981 ttatggtact ctttacagga tcagctgcta agcttagctg gtttatctac acgcctcgat
   113041 ttttcggagc aaccttgatt ggtacagcga tttcctttat tgcctttcga tttttaatca
   113101 agcaggaatt ctttaaaaaa gtgcagggat atttctttag tgaaaggata gactgatgca
   113161 ggaatttaca aatccctttc ctataggctc tagttccctc attcactgta tgaccaatga
   113221 gatttcttgt gagatgctgg caaatgggat tttggctctg ggatgcaaac ctgtcatggc
   113281 agatgatccc cgtgaggttc ttgattttac taagcaaagt caggctctct tcatcaattt
   113341 ggggcatttg tcagctgaga aggagaaagc aatccgtata gcagcttctt atgcagctca
   113401 agtttgtctc ccaatggtag tagatgcggt tggcgtaaca gcttcatcca ttcgtaagag
   113461 cttagtcaga gaccttttag actatagacc tacggtcctt aaaggaaaca tgtcagaaat
   113521 tcgaagtctt gttggattaa agcaccacgg cgttggggtc gatgcgagtg ctaaagatca
   113581 agaaacggag gatttgcttc aagtcttgaa agactggtgt cagacctatc atggtatgtc
   113641 tttcttagtc acaggtccca aggacctcgt cgtttcgaaa aatcaggtcg ctgtactggg
   113701 aaatggctgt gcagaattag actggataac agggacagga gatttggttg gagccttaac
   113761 agccgttttt ctcagccaag gaaagactgg ttttgaagct tcttgcttag cagtctctta
   113821 tctcaatatc gctgctgaga aaatagttgt tcaaggaatg ggattggaag aatttcgtta
   113881 ccaagtactc aatcagcttt cgctcctaag aagagatgaa aattggctag ataccatcaa
   113941 aggagaggtt tatgaataga gaagcactta gactatatct ggtaaccaat cgctatcaag
   114001 attccgtgga aagctttctt gcaaaagttg agacggcctg ccgttcaggg gttaccatag
   114061 tccaattgcg agaaaaaaat ctcacaacca atcaatatta tcaactggca aaacaagtca
   114121 aggaaataac agatgcttat caggtaccct tgataatcga tgatcggttg gatgtttgtc
   114181 ttgcggttga tgctgctggt ctgcatattg gagatgacga actcccagtt tcggttgccc
   114241 gacaagtctt gggtcctgaa aaaatcctcg gtgtcaccgc taaaacggtt aaaagagctc
   114301 tggaagcgga gaaatcaggt gcagattact tgggtacagg agccattttc ccaaccacca
   114361 ccaaggaaaa tgcgcccatt actctgatat cgaccttgaa aacaatttgc caaacggttg
   114421 ccattccagt agttgctatt ggaggcttga cttcggagaa tattgatcag cttatgggca
   114481 ctggcatagc tggtgtagct gttgtacgtg atttgatgca agcagaagat attgaggcaa
   114541 aaacgcaagc ctttttaaca aagttgcatg acattctttc ctaattaata ctcaatgaaa
   114601 atcaaagagt aaactagaaa gctagtcgca ggttgctcaa agtactgcct tgaggtttta
   114661 gataagactg acgaagtcag ctcaaaacag tgttttgagg ttgcagatgg aagctgacgt
   114721 agtttgaaga gattttcgaa gagtataaaa actctctaat tcccttaaag tgggaactag
   114781 agagtttttt ttcttaatct ttaaaagttg tatggttgac tggaccagaa ccatgaccga
   114841 gttgaggggc atcttgaata gcttttgtga taaaggcctt ggccttatca actgcctggt
   114901 aaagactctt gcccttggct agttcagcag taatcactgc agcaaaggta catccagtac
   114961 catgggtgtg acaggtttga attcgtgggc tttcccagac aaattgttca ttcttggtaa
   115021 agaggaaatc tttagcacca cctttgagat gtccgccttt gataaccaca gactgaggac
   115081 caaattcttt taaaatcagg cgaccagcac gctgcatgtc ttcggggtca tggattgaaa
   115141 aaccaacaat ctcttctgct tcaggaagat ttggcgtaat aatagttgct agaggtagta
   115201 agtttgtttt gagatagtct ctagcacttg agtcaatcaa ggcatctcca cttgtagcaa
   115261 ccataacagg atcaaggaca tagggacaat ccagtttttt aagatagggt tggatgattt
   115321 ccatgatttc agtagtagcc aacattccag tttttacagc ctgaggtgga atatcagaaa
   115381 agacactgtc caattgggct ttcaacattt gaggagaaac gtgttcgatt agctgaacac
   115441 ctctggtatt ttgagcgaca agactggtta caacagccat tccataggca tctctcgctt
   115501 ggaatgactt taaatctgcc ataatgccag caccaccact agggtcagtc cctgcaatgg
   115561 tcaaagcaac gggtaaataa gtcatctaaa acctcccaac caactgaagt ttgtattctt
   115621 aagaacaagc tagtctgttt tagaaaggca atagaagact gctagtcccc attatcattt
   115681 ccacttccat cagctagcat tacctagatt gagtcagagg gatctaacag tcgttaatct
   115741 cagctttacg cacccctagt ggttgttttc ttttttcttt agtatagcat atttttattg
   115801 tttatatagt aatatttgac tgcaaatcgt ttttcaaatg attaaaattc tatttttcga
   115861 agaaaatatt atttctataa ttgacaaatg tagattttga gagtatactg atgagtgtaa
   115921 ttgacaaatg tagattttgg aggtatggta atgcagattt cagatgcaga atggcaggtc
   115981 atgaagatta tttggatgca gggggagcag accagtacag atttgattag ggttttggca
   116041 gagcggtttg attggtccaa gtcaacggtt cagacacttt tgtctcggct ggttgagaaa
   116101 gagtgtttga ctcggaaaaa agaaggcaag tcctttgttt attcagccct tttaactcta
   116161 gaccaaagtc gggatttact tgtccaagat atcaaagaca aggtttgttc ccgtaggatt
   116221 aggaatttgt tggctgactt gattgtagaa tgtgaattta ctcagactga cttggaagac
   116281 ttggaagctg tgatttcaga gaagaaatca agtgctgtaa cagaagtaag atgtaattgt
   116341 atgtaaagga gacgtcatgt taaatagtat tgtaaccatt atttgtattg cccttatcgc
   116401 gtttatcttg ttttggtttt tcaaaaagcc tgaaaaatct ggacaaaaag cccagcaaaa
   116461 aaatggatac caagagattc gagtggaagt catgggaggc tatactcctg agttgattgt
   116521 cctcaagaaa tcagtgccag cacgcattgt ctttgaccgc aaggatcctt caccatgtct
   116581 ggatcaaatt gtttttccag attttggtgt acatacgaac ctgccaatgg gggaagagta
   116641 tgtagtggaa atcacgcctg agcaggctgg agagtttggc tttgcttgtg gtatgaacat
   116701 gatgcacggc aagatgattg tagagtaggt ggagactatg acagaaattg tgaaagcaag
   116761 cttagaaaat ggcattcaaa aaatccgtat ccgagctgaa aaaggctatc atccagccca
   116821 tatccagctt caaaagggaa ttccagctga gattaccttt catcgtgcta ctccttcaaa
   116881 ctgttataag gaaattctgt ttgaagaaga aggtatcttg gaaccaatcg gcgtagatga
   116941 ggagaaagtc attcgtttta cacctcaaga attagggcga catgaatttt cttgtggcat
   117001 gaagatgcaa aagggaagct atacagtcgt tgagaagact cgaaaatctc tatctctcct
   117061 gcaacgtttt tggattacta gtatctttac tgtgcctctt gtgattctca tgattgggat
   117121 gttgacaggt agcattagtc atcaagtcat gcattgggga acctttctag caacaacgac
   117181 tattatgtta gttgcaggta agccatatat ccagagtgct tgggccagtt ttaaaaagca
   117241 caatgccaac atggatacct tggttgcgct gggaactcta gtggcttatt tctatagcct
   117301 agttgctctc tttgctggtc tccctgttta cttcgaaagt gctggattta tcctcttttt
   117361 cgttcttttg ggagcagttt ttgaggaaaa aatgagaaaa aatacgtccc aagctgtgga
   117421 gaaattactg gacttgcaag ctaaaaccgc agaagtcttg agtgatgata gttatgtcca
   117481 agttcctttg gaacaagtca aggtaggcga cctgattcga gtgcgtcccg gtgaaaagat
   117541 tgctgttgat ggtgtcgtag tagaaggtgt ctctagtatt gacgaatcca tggtgacagg
   117601 tgagagtctg cctgtggaca agacagttgg agatactgtc attggctcaa ccatcaatca
   117661 tagtggaacg cttgtcttta gagcagaaaa agttggctca gagactgttt tggctcagat
   117721 tgtggatttt gtgaagaaag ctcagacaag tcgtgcgccg attcaagact tgacggataa
   117781 gatttcaggg atttttgtcc cagtagttgt cattttagga atcatgacct tttgggtttg
   117841 gttcgtcttg ctcagggata gtgtggttgt gcttggagct agctttgtgt cctctcttct
   117901 ctacggagtg gcggttttga ttatcgcctg tccttgtgcc ttgggacttg caacaccgac
   117961 agcccttatg gtggggacag gacgtagtgc caagatgggg gttctcctca aaaatggaac
   118021 tgtcttacag gaaatccaga aagttcaaac ccttgtcttt gataagaccg ggactttgac
   118081 ggaagggaaa cctgtggtaa cagatgtcat cggcgacgaa gtagaagtgt ttaggttggc
   118141 agcctccttg gaagatgctt ctcaacaccc actggctgag gctatcgtta agcgagcgag
   118201 tgaagctgga cttgagtttc aaactgttga aaattttcag accttgcacg ggaaaggtgt
   118261 ttcagggcga atcaatggaa aacaagtttt acttggaaat gctaaaatgc tggatggcat
   118321 ggatatttct aatacttatc aagataaact agaagaacta gaaaaagaag ctaagacagt
   118381 tgtgttctta gctgttgaca atgaaatcaa aggcttgctt gctttgcaag atattcctaa
   118441 ggaaaatgct aagctagcca tcagtcagct aaaaaaacgt ggtctccgaa cagtcatgct
   118501 gacaggagac aatgctggtg tggcgcgtgc tattgcagat caaatcggaa ttgaagaggt
   118561 cattgcaggc gtcttgccag aagaaaaagc ccatgaaatc cataaactgc aacagtcagg
   118621 gaaagtagcc tttgttgggg acggtatcaa tgacgctcct gcccttagtg tagcagatgt
   118681 ggggattgct atgggagctg gaacagatat cgccatcgag tcagcagatt tggtgttgac
   118741 aaccaataat cttttaggag tggttcgtgc ctttgatatg agtaagaaaa cctttcatcg
   118801 aattctactc aatcttttct gggcttttat ctacaatgtt gtcggaattc cgattgcagc
   118861 aggagtcttt tcaggtgttg gactggctct caacccagaa ttggcaggtc tagccatggc
   118921 ctttagttct gtatctgttc tgaccagttc ccttctgtta aattttagta aaatagacta
   118981 aaagtaatga ctagatttct ttgttataaa acagaaatga cagaactttc aaaactgtat
   119041 tagaatagag aatagagagt tttgagcaga tttttagaaa agtcagcata aatatgatac
   119101 agtggaatag taaaaatttg gagaacgttt ccaattctat gtaatcgtat tctccaaatc
   119161 taaaaaaatt gaaggagagt tatcattatg actcaaggga aaattactgc atctgcagca
   119221 atgcttaacg tattgaaaac atggggcgta gatacaatct acggtatccc atcaggaaca
   119281 ctcagctcat tgatggacgc tttggctgaa gacaaagata tccgcttctt acaagttcgc
   119341 cacgaagaga caggtgctct tgcagcggtt atgcaagcta aattcggcgg ctcaatcggg
   119401 gttgcagttg gttcaggtgg tccaggtgcg actcacttga ttaacggtgt ttacgatgca
   119461 gctatggata acactccatt cctagcgatc cttggatcac gtccagttaa cgaattgaac
   119521 atggatgctt tccaagagct taaccaaaac ccaatgtaca acggtatcgc tgtttacaac
   119581 aaacgtgtag cttacgctga gcaattgcca aaagtaattg acgaagcctg ccgtgctgca
   119641 atttctaaaa aaggtccagc tgttgttgaa attccagtaa acttcggttt ccaagaaatc
   119701 gacgaaaact catactacgg ttcaggttca tacgaacgct cattcatcgc tcctgctttg
   119761 aacgaagttg aaatcgacaa agctgttgaa atcttgaaca atgctgaacg cccagttatc
   119821 tatgctggat ttggtggtgt taaagctggt gaagtgatta ctgaattgtc acgtaaaatc
   119881 aaagcaccaa tcatcacaac tggtaaaaac tttgaagctt tcgaatggaa ctatgaaggt
   119941 ttgacaggtt ctgcttatcg tgttggttgg aaaccagcca acgaagtggt ctttgaagca
   120001 gacacagttc ttttccttgg ttcaaacttc ccatttgctg aagtttacga agcattcaag
   120061 aacactgaaa aattcatcca agttgatatc gacccttaca aacttggtaa acgtcatgcc
   120121 cttgacgctt caatccttgg tgatgctggt caagcagcta aagctatcct tgacaaagta
   120181 aacccagttg aatcaactcc atggtggcgt gcaaacgtta agaacaacca aaactggcgt
   120241 gattacatga acaaactcga aggtaaaact gagggtgaat tgcaattgta tcaagtttac
   120301 aatgcaatca acaaacatgc tgatcaagac gctatctact caatcgacgt aggtaacact
   120361 actcaaacat ctactcgtca ccttcacatg acacctaaga acatgtggcg tacatctcca
   120421 ctctttgcga caatgggtat tgcccttcct ggtggtatcg ctgctaagaa agacaatcca
   120481 gatcgccaag tatggaacat catgggtgat ggagcattca acatgtgcta cccagacgtt
   120541 atcacaaacg ttcaatacga ccttccagtt atcaaccttg tcttctcaaa tgctgagtac
   120601 ggcttcatca agaacaaata cgaagataca aacaaacact tgtttggtgt agacttcaca
   120661 aacgctgact acgctaaaat tgcggaagct caaggagctg ttggattcac agttgaccgt
   120721 atcgaagaca tcgatgcagt tgttgcagaa gctgttaaat tgaacaaaga aggtaaaact
   120781 gttgtcatcg atgctcgcat cactcaacac cgtccacttc cagtagaagt acttgaattg
   120841 gatccaaaac ttcactcaga agaagctatc aaagccttca aggaaaaata cgaagcagaa
   120901 gaactcgtac cattccgtct cttcttggaa gaagaaggat tgcaatcacg cgcaattaaa
   120961 taattcctct cgccgaaaat caaatatgaa acttgtagac tttattcttt gattttcata
   121021 gagcagaact ttaaaagatc ggagcaatcc ggtcttttta tggaggagag taaatgaatt
   121081 taaatcaatt agatattatc gtttcaaatg ttccccaagt ctgtgctgac ttggagcata
   121141 ttttggataa aaaggcagat tatgctgatg atggttttgc tcagtttacg attggtagtc
   121201 actgccttat gttgtcacaa aatcatttgg ttcctttgga aaactttcag tcaggaatca
   121261 ttattcatat cgaggttgag gatgtagacc agaactacaa acggttgaac gagcttggta
   121321 taaaggtttt acacggacca actgtaaccg attggggaac agagtcctta ttagttcaag
   121381 gacctgctgg tctagtgctt gatttttatc gtatgaaata ggtcgcgtag tcatttgacg
   121441 ttaaccttag ctatttttaa aatagaaatt gagaatatga actattgaaa gatcggagca
   121501 atccggtctt tttatataaa gaaattgcat ataatactca tctg
//
LOCUS       DBEJZJ010000002       118128 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000002 DBEJZJ010000000
VERSION     DBEJZJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 118128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118128
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.02"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(51..377)
                     /locus_tag="ACL3R8_000125"
     CDS             complement(51..377)
                     /locus_tag="ACL3R8_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313087.1"
                     /translation="MILWSFDFANDHAHTFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(704..2584)
                     /locus_tag="ACL3R8_000126"
     CDS             complement(704..2584)
                     /locus_tag="ACL3R8_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR1313088.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2578..3447)
                     /locus_tag="ACL3R8_000127"
     CDS             complement(2578..3447)
                     /locus_tag="ACL3R8_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR1313089.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3531..6176)
                     /locus_tag="ACL3R8_000128"
     CDS             complement(3531..6176)
                     /locus_tag="ACL3R8_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR1313090.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPELL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RLYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6267..7547)
                     /locus_tag="ACL3R8_000129"
     CDS             complement(6267..7547)
                     /locus_tag="ACL3R8_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR1313091.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7718..9802
                     /locus_tag="ACL3R8_000130"
     CDS             7718..9802
                     /locus_tag="ACL3R8_000130"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR1313092.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKLGILFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTSFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLTQYQELGYLSTDHNESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(9842..11521)
                     /locus_tag="ACL3R8_000131"
     CDS             complement(9842..11521)
                     /locus_tag="ACL3R8_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR1313093.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFKKWFETTRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDAALPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12276..13505
                     /gene="arcA"
                     /locus_tag="ACL3R8_000132"
     CDS             12276..13505
                     /gene="arcA"
                     /locus_tag="ACL3R8_000132"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR1313094.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHDIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13563..14579
                     /gene="argF"
                     /locus_tag="ACL3R8_000133"
     CDS             13563..14579
                     /gene="argF"
                     /locus_tag="ACL3R8_000133"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR1313095.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14744..15691
                     /gene="arcC"
                     /locus_tag="ACL3R8_000134"
     CDS             14744..15691
                     /gene="arcC"
                     /locus_tag="ACL3R8_000134"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR1313096.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15900..17411
                     /locus_tag="ACL3R8_000135"
     CDS             15900..17411
                     /locus_tag="ACL3R8_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR1313097.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17433..18764
                     /locus_tag="ACL3R8_000136"
     CDS             17433..18764
                     /locus_tag="ACL3R8_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR1313098.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGTFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            18860..18967
                     /locus_tag="ACL3R8_000137"
                     /pseudo
     CDS             18860..18967
                     /locus_tag="ACL3R8_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19171..19461)
                     /locus_tag="ACL3R8_000138"
     CDS             complement(19171..19461)
                     /locus_tag="ACL3R8_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR1313099.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19449..19700)
                     /locus_tag="ACL3R8_000139"
     CDS             complement(19449..19700)
                     /locus_tag="ACL3R8_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR1313100.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20099..20983)
                     /locus_tag="ACL3R8_000140"
     CDS             complement(20099..20983)
                     /locus_tag="ACL3R8_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR1313101.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21128..22279)
                     /locus_tag="ACL3R8_000141"
     CDS             complement(21128..22279)
                     /locus_tag="ACL3R8_000141"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR1313102.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22425..24191)
                     /locus_tag="ACL3R8_000142"
     CDS             complement(22425..24191)
                     /locus_tag="ACL3R8_000142"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR1313103.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24204..24932)
                     /locus_tag="ACL3R8_000143"
     CDS             complement(24204..24932)
                     /locus_tag="ACL3R8_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGR1313104.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIWCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(24947..27964)
                     /locus_tag="ACL3R8_000144"
     CDS             complement(24947..27964)
                     /locus_tag="ACL3R8_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 98 domain-containing
                     protein"
                     /protein_id="HGR1313105.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLTKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(27975..30191)
                     /locus_tag="ACL3R8_000145"
     CDS             complement(27975..30191)
                     /locus_tag="ACL3R8_000145"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR1313106.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCVETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSRFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(30213..32083)
                     /locus_tag="ACL3R8_000146"
                     /pseudo
     CDS             complement(30213..32083)
                     /locus_tag="ACL3R8_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
     gene            complement(32089..33408)
                     /locus_tag="ACL3R8_000147"
     CDS             complement(32089..33408)
                     /locus_tag="ACL3R8_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR1313107.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDRYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(33405..34244)
                     /locus_tag="ACL3R8_000148"
     CDS             complement(33405..34244)
                     /locus_tag="ACL3R8_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313108.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPIDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(34247..35176)
                     /locus_tag="ACL3R8_000149"
     CDS             complement(34247..35176)
                     /locus_tag="ACL3R8_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313109.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            35209..35850
                     /locus_tag="ACL3R8_000150"
                     /pseudo
     CDS             35209..35850
                     /locus_tag="ACL3R8_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
     gene            complement(36979..38484)
                     /gene="adcA"
                     /locus_tag="ACL3R8_000151"
     CDS             complement(36979..38484)
                     /gene="adcA"
                     /locus_tag="ACL3R8_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR1313110.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(38494..39300)
                     /locus_tag="ACL3R8_000152"
     CDS             complement(38494..39300)
                     /locus_tag="ACL3R8_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR1313111.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(39293..39997)
                     /locus_tag="ACL3R8_000153"
     CDS             complement(39293..39997)
                     /locus_tag="ACL3R8_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR1313112.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNVGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(39997..40437)
                     /gene="adcR"
                     /locus_tag="ACL3R8_000154"
     CDS             complement(39997..40437)
                     /gene="adcR"
                     /locus_tag="ACL3R8_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR1313113.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(40592..41860)
                     /gene="dltD"
                     /locus_tag="ACL3R8_000155"
     CDS             complement(40592..41860)
                     /gene="dltD"
                     /locus_tag="ACL3R8_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR1313114.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(41853..42092)
                     /gene="dltC"
                     /locus_tag="ACL3R8_000156"
     CDS             complement(41853..42092)
                     /gene="dltC"
                     /locus_tag="ACL3R8_000156"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR1313115.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(42106..43350)
                     /gene="dltB"
                     /locus_tag="ACL3R8_000157"
     CDS             complement(42106..43350)
                     /gene="dltB"
                     /locus_tag="ACL3R8_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR1313116.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(43347..44897)
                     /gene="dltA"
                     /locus_tag="ACL3R8_000158"
     CDS             complement(43347..44897)
                     /gene="dltA"
                     /locus_tag="ACL3R8_000158"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR1313117.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(44918..45049)
                     /locus_tag="ACL3R8_000159"
     CDS             complement(44918..45049)
                     /locus_tag="ACL3R8_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR1313118.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(45280..45984)
                     /locus_tag="ACL3R8_000160"
     CDS             complement(45280..45984)
                     /locus_tag="ACL3R8_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR1313119.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(46054..47880)
                     /gene="glpO"
                     /locus_tag="ACL3R8_000161"
     CDS             complement(46054..47880)
                     /gene="glpO"
                     /locus_tag="ACL3R8_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR1313120.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(47922..49430)
                     /gene="glpK"
                     /locus_tag="ACL3R8_000162"
     CDS             complement(47922..49430)
                     /gene="glpK"
                     /locus_tag="ACL3R8_000162"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR1313121.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(49589..51016)
                     /locus_tag="ACL3R8_000163"
                     /pseudo
     CDS             complement(49589..51016)
                     /locus_tag="ACL3R8_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            51181..52053
                     /gene="hslO"
                     /locus_tag="ACL3R8_000164"
     CDS             51181..52053
                     /gene="hslO"
                     /locus_tag="ACL3R8_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR1313122.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            52040..53020
                     /gene="dusB"
                     /locus_tag="ACL3R8_000165"
     CDS             52040..53020
                     /gene="dusB"
                     /locus_tag="ACL3R8_000165"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR1313123.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(53250..55337)
                     /gene="pspC"
                     /locus_tag="ACL3R8_000166"
     CDS             complement(53250..55337)
                     /gene="pspC"
                     /locus_tag="ACL3R8_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR1313124.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFLGGVVHAEGVGGRN
                     TSTVTSSGQDTSKKYADEVKSHYQSILEKVRKSLEKDRHTQNVGLITKLSEIKKKYLY
                     ELEVNVLLEEKSKAELPSKAKAELDAAFEQFKKEPELTKKVAEAQKKVEEAKKKAEDQ
                     KEEDFRNYPTNTYKTIELEIAESDVKVKEAELELLKEEAKEHRDEGTIKQVEEKVKSE
                     KAEATRLEEIKTERKKAEEEAKRRADAKEQGKPKGRAKRGVPGEQATPDKKENDAKSS
                     DSSVGEETLPNPSLKPEKKVAEAQKKVEEAKKKAKDQKEEDHRNYPTITYKTLELEIA
                     ESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEAK
                     RKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGAMATGWLQNNGSWYYLNDNGDMATGWLQNNGSWYYLNANGSMVTGWLQNNG
                     SWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTV
                     DSYRVNANGEWVN"
     gene            complement(55416..55943)
                     /locus_tag="ACL3R8_000167"
     CDS             complement(55416..55943)
                     /locus_tag="ACL3R8_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR1313125.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(56026..57366)
                     /gene="hk06"
                     /locus_tag="ACL3R8_000168"
     CDS             complement(56026..57366)
                     /gene="hk06"
                     /locus_tag="ACL3R8_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR1313126.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(57363..58016)
                     /gene="rr06"
                     /locus_tag="ACL3R8_000169"
     CDS             complement(57363..58016)
                     /gene="rr06"
                     /locus_tag="ACL3R8_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR1313127.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(58277..60709)
                     /locus_tag="ACL3R8_000170"
     CDS             complement(58277..60709)
                     /locus_tag="ACL3R8_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR1313128.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(60711..61169)
                     /locus_tag="ACL3R8_000171"
     CDS             complement(60711..61169)
                     /locus_tag="ACL3R8_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR1313129.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(61288..62016)
                     /locus_tag="ACL3R8_000172"
     CDS             complement(61288..62016)
                     /locus_tag="ACL3R8_000172"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313130.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(62016..63023)
                     /locus_tag="ACL3R8_000173"
     CDS             complement(62016..63023)
                     /locus_tag="ACL3R8_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313131.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(63062..63820)
                     /locus_tag="ACL3R8_000174"
     CDS             complement(63062..63820)
                     /locus_tag="ACL3R8_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313132.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(63783..64073)
                     /locus_tag="ACL3R8_000175"
     CDS             complement(63783..64073)
                     /locus_tag="ACL3R8_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR1313133.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(64144..64246)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(64329..65675)
                     /gene="cbpD"
                     /locus_tag="ACL3R8_000176"
     CDS             complement(64329..65675)
                     /gene="cbpD"
                     /locus_tag="ACL3R8_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR1313134.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGYKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(65764..66030)
                     /locus_tag="ACL3R8_000177"
     CDS             complement(65764..66030)
                     /locus_tag="ACL3R8_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR1313135.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(66032..67384)
                     /gene="dnaB"
                     /locus_tag="ACL3R8_000178"
     CDS             complement(66032..67384)
                     /gene="dnaB"
                     /locus_tag="ACL3R8_000178"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR1313136.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(67428..67880)
                     /gene="rplI"
                     /locus_tag="ACL3R8_000179"
     CDS             complement(67428..67880)
                     /gene="rplI"
                     /locus_tag="ACL3R8_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR1313137.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(67877..69850)
                     /locus_tag="ACL3R8_000180"
     CDS             complement(67877..69850)
                     /locus_tag="ACL3R8_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR1313138.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSKAGEKLTEIVLNEIKEKEKEE"
     gene            complement(69986..70534)
                     /gene="raiA"
                     /locus_tag="ACL3R8_000181"
     CDS             complement(69986..70534)
                     /gene="raiA"
                     /locus_tag="ACL3R8_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR1313139.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(70614..71276)
                     /locus_tag="ACL3R8_000182"
     CDS             complement(70614..71276)
                     /locus_tag="ACL3R8_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR1313140.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(71273..72571)
                     /locus_tag="ACL3R8_000183"
     CDS             complement(71273..72571)
                     /locus_tag="ACL3R8_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1313141.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            72627..73262
                     /locus_tag="ACL3R8_000184"
     CDS             72627..73262
                     /locus_tag="ACL3R8_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR1313142.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            73547..74467
                     /gene="cysK"
                     /locus_tag="ACL3R8_000185"
     CDS             73547..74467
                     /gene="cysK"
                     /locus_tag="ACL3R8_000185"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR1313143.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(74706..75071)
                     /locus_tag="ACL3R8_000186"
                     /pseudo
     CDS             complement(74706..75071)
                     /locus_tag="ACL3R8_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_068988785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            75053..75361
                     /locus_tag="ACL3R8_000187"
                     /pseudo
     CDS             75053..75361
                     /locus_tag="ACL3R8_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(75552..75839)
                     /gene="tnpB"
                     /locus_tag="ACL3R8_000188"
     CDS             complement(75552..75839)
                     /gene="tnpB"
                     /locus_tag="ACL3R8_000188"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1313144.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(76085..77125)
                     /gene="tsf"
                     /locus_tag="ACL3R8_000189"
     CDS             complement(76085..77125)
                     /gene="tsf"
                     /locus_tag="ACL3R8_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR1313145.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(77204..77983)
                     /gene="rpsB"
                     /locus_tag="ACL3R8_000190"
     CDS             complement(77204..77983)
                     /gene="rpsB"
                     /locus_tag="ACL3R8_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR1313146.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(78207..79385)
                     /gene="pcsB"
                     /locus_tag="ACL3R8_000191"
     CDS             complement(78207..79385)
                     /gene="pcsB"
                     /locus_tag="ACL3R8_000191"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR1313147.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(79479..79973)
                     /gene="mreD"
                     /locus_tag="ACL3R8_000192"
     CDS             complement(79479..79973)
                     /gene="mreD"
                     /locus_tag="ACL3R8_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR1313148.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(79973..80791)
                     /gene="mreC"
                     /locus_tag="ACL3R8_000193"
     CDS             complement(79973..80791)
                     /gene="mreC"
                     /locus_tag="ACL3R8_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR1313149.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(80850..81644)
                     /locus_tag="ACL3R8_000194"
     CDS             complement(80850..81644)
                     /locus_tag="ACL3R8_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1313150.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(81637..82476)
                     /locus_tag="ACL3R8_000195"
     CDS             complement(81637..82476)
                     /locus_tag="ACL3R8_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR1313151.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(82461..83288)
                     /locus_tag="ACL3R8_000196"
     CDS             complement(82461..83288)
                     /locus_tag="ACL3R8_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR1313152.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            complement(83285..83830)
                     /gene="pgsA"
                     /locus_tag="ACL3R8_000197"
     CDS             complement(83285..83830)
                     /gene="pgsA"
                     /locus_tag="ACL3R8_000197"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR1313153.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(83841..84662)
                     /gene="rodZ"
                     /locus_tag="ACL3R8_000198"
     CDS             complement(83841..84662)
                     /gene="rodZ"
                     /locus_tag="ACL3R8_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR1313154.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(84704..85987)
                     /locus_tag="ACL3R8_000199"
     CDS             complement(84704..85987)
                     /locus_tag="ACL3R8_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR1313155.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(85984..87234)
                     /locus_tag="ACL3R8_000200"
                     /pseudo
     CDS             complement(85984..87234)
                     /locus_tag="ACL3R8_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
     gene            87393..87761
                     /gene="yaaA"
                     /locus_tag="ACL3R8_000201"
     CDS             87393..87761
                     /gene="yaaA"
                     /locus_tag="ACL3R8_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR1313156.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            87764..88861
                     /gene="recF"
                     /locus_tag="ACL3R8_000202"
     CDS             87764..88861
                     /gene="recF"
                     /locus_tag="ACL3R8_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR1313157.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(88912..90390)
                     /gene="guaB"
                     /locus_tag="ACL3R8_000203"
     CDS             complement(88912..90390)
                     /gene="guaB"
                     /locus_tag="ACL3R8_000203"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR1313158.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(90542..91567)
                     /gene="trpS"
                     /locus_tag="ACL3R8_000204"
     CDS             complement(90542..91567)
                     /gene="trpS"
                     /locus_tag="ACL3R8_000204"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR1313159.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            91773..93395
                     /locus_tag="ACL3R8_000205"
     CDS             91773..93395
                     /locus_tag="ACL3R8_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313160.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIIVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            93457..96009
                     /locus_tag="ACL3R8_000206"
     CDS             93457..96009
                     /locus_tag="ACL3R8_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR1313161.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFNLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(96039..97692)
                     /locus_tag="ACL3R8_000207"
                     /pseudo
     CDS             complement(96039..97692)
                     /locus_tag="ACL3R8_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            97820..98362
                     /locus_tag="ACL3R8_000208"
     CDS             97820..98362
                     /locus_tag="ACL3R8_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR1313162.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(98403..98476)
                     /locus_tag="ACL3R8_000209"
     tRNA            complement(98403..98476)
                     /locus_tag="ACL3R8_000209"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98440..98442),aa:Asn,seq:gtt)
     gene            complement(98482..98553)
                     /locus_tag="ACL3R8_000210"
     tRNA            complement(98482..98553)
                     /locus_tag="ACL3R8_000210"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98518..98520),aa:Glu,seq:ttc)
     gene            complement(98605..99357)
                     /gene="comE"
                     /locus_tag="ACL3R8_000211"
     CDS             complement(98605..99357)
                     /gene="comE"
                     /locus_tag="ACL3R8_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR1313163.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(99354..100679)
                     /gene="comD"
                     /locus_tag="ACL3R8_000212"
     CDS             complement(99354..100679)
                     /gene="comD"
                     /locus_tag="ACL3R8_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR1313164.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(100700..100825)
                     /gene="comC"
                     /locus_tag="ACL3R8_000213"
     CDS             complement(100700..100825)
                     /gene="comC"
                     /locus_tag="ACL3R8_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR1313165.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(100990..101063)
                     /locus_tag="ACL3R8_000214"
     tRNA            complement(100990..101063)
                     /locus_tag="ACL3R8_000214"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(101027..101029),aa:Arg,seq:tct)
     gene            complement(101107..101586)
                     /gene="rlmH"
                     /locus_tag="ACL3R8_000215"
     CDS             complement(101107..101586)
                     /gene="rlmH"
                     /locus_tag="ACL3R8_000215"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR1313166.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            101769..102950
                     /locus_tag="ACL3R8_000216"
     CDS             101769..102950
                     /locus_tag="ACL3R8_000216"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR1313167.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            103008..103766
                     /locus_tag="ACL3R8_000217"
     CDS             103008..103766
                     /locus_tag="ACL3R8_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR1313168.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEALAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            103979..105340
                     /gene="dnaA"
                     /locus_tag="ACL3R8_000218"
     CDS             103979..105340
                     /gene="dnaA"
                     /locus_tag="ACL3R8_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR1313169.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            105499..106635
                     /gene="dnaN"
                     /locus_tag="ACL3R8_000219"
     CDS             105499..106635
                     /gene="dnaN"
                     /locus_tag="ACL3R8_000219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR1313170.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNITITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            106700..106894
                     /locus_tag="ACL3R8_000220"
     CDS             106700..106894
                     /locus_tag="ACL3R8_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR1313171.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            106978..108093
                     /gene="ychF"
                     /locus_tag="ACL3R8_000221"
     CDS             106978..108093
                     /gene="ychF"
                     /locus_tag="ACL3R8_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR1313172.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRASYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            108164..108733
                     /gene="pth"
                     /locus_tag="ACL3R8_000222"
     CDS             108164..108733
                     /gene="pth"
                     /locus_tag="ACL3R8_000222"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR1313173.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            108734..112243
                     /gene="mfd"
                     /locus_tag="ACL3R8_000223"
     CDS             108734..112243
                     /gene="mfd"
                     /locus_tag="ACL3R8_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR1313174.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASHPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSCLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIVENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            112301..112567
                     /locus_tag="ACL3R8_000224"
     CDS             112301..112567
                     /locus_tag="ACL3R8_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR1313175.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            112560..112928
                     /locus_tag="ACL3R8_000225"
     CDS             112560..112928
                     /locus_tag="ACL3R8_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR1313176.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            112933..113055
                     /locus_tag="ACL3R8_000226"
     CDS             112933..113055
                     /locus_tag="ACL3R8_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR1313177.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            113048..114316
                     /locus_tag="ACL3R8_000227"
     CDS             113048..114316
                     /locus_tag="ACL3R8_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR1313178.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            114313..115590
                     /gene="tilS"
                     /locus_tag="ACL3R8_000228"
     CDS             114313..115590
                     /gene="tilS"
                     /locus_tag="ACL3R8_000228"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR1313179.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFKKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRNAILGISNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            115594..116136
                     /gene="hpt"
                     /locus_tag="ACL3R8_000229"
     CDS             115594..116136
                     /gene="hpt"
                     /locus_tag="ACL3R8_000229"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR1313180.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            116152..118110
                     /gene="ftsH"
                     /locus_tag="ACL3R8_000230"
     CDS             116152..118110
                     /gene="ftsH"
                     /locus_tag="ACL3R8_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR1313181.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT        36248 a        24633 c        20887 g        36360 t
ORIGIN      
        1 atactaagcc tacacacaga ctgattccaa ttgtttttta gatttcaatt ttaccattct
       61 tcatagtcaa aaccatcata atctggatat tgttctggcg acgttccaac cgaacgtacg
      121 agataagctt cttcgtcctc tgtctcgatt tctctcagca cttggcattc aaaacgccat
      181 tcatcaccga agtcgaaaat aaacttaaat ttttgtttga cacttaggct atccagatag
      241 acattttctg tgtaacgttc ttcaacatcg tcactaacaa agctaagaaa gtaagaatct
      301 gcatgactcc actcaacatt atccatgaaa aatgtgtgag catgatcatt tgcaaaatca
      361 aaactccata aaatcacatc tgctagttcc gctaacgttt ttgtttttgg aatctatata
      421 tgtcggtagc aacctttttt aaatttgacg gaaatgatcc aagcttctac agatgctggc
      481 ttttcagctt ctatttcttg ttttactaat tttaactgta gcatttgaaa ccagataatt
      541 cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt tcttgttttt atactcaatg
      601 aaaatcaaag agcaaactag gaagctagct gcaggctgct caaaacactg ttttgaggtt
      661 gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga gtattaagtc gtataaatcg
      721 tcgacgctgt cgcaatggta tgccactggt tggctgttgt agctgcgaaa tccttgtctg
      781 cgtagaagtc agtaaatggt aggatttcaa cttccagctc gtcgatgcgg tcaagctggc
      841 cagccagata aacctcgata cggctttctg ctcgtttgat gcgttgcaag agtccgccca
      901 tacggatgtc aactgtatcc aaaccaaaga ccttgttttc tttcagccat tggtggctaa
      961 agagggcatg gaagtcttca atttggcttc taagttctgg taattcttgt ctggcgattt
     1021 gttgtaaact ttctttatca tccgcttggt aggcctgacg aatgcgtcgt cccacatcta
     1081 ctttgctact taaaatagca ttcaactggg cctgagtttc aaagagataa gcatagtttc
     1141 cagctttttc tttaatgtta gcaagcgtct cagcagcctg agcgaagtgt ggcttgtcct
     1201 gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac atcctgataa aagacatatc
     1261 ggttgggatt gatgccactg agattacctg gtaggtctgg taaaaggttg gcaaggtcaa
     1321 tctgcataaa atcttcaacc gttagaccag tattggtctt gaaatgcgca gacaaactat
     1381 ctaggtcatt gcgatagctg agttctgccc agatttgcaa gcttggtagg atagagaact
     1441 gggcagtttc accaccattg tctccccaac ccgttacgat gacttcttta atctgattgg
     1501 cacggcaggc tttattagcc tcgatagcca ctagacggct aaaatggttg tgaggtgtaa
     1561 agccaatcca cttccaagct ccccctgcaa atgcaaggtc atggctaatc ttgtgatgat
     1621 tgcggaaatt acggttgtat ttttcctcgc tatcctgata ataatcccag taaaccagag
     1681 tcacacggtc tttgagacgg tctaggtaga cacgagtttc ctctggaatt tccacatcac
     1741 ggtcgtactg gccatccgct gacatgagtt tgaagaacat atcactccac atctggcagt
     1801 ggaaaccata tttgtcagca atatccagca cgcgctccaa gtgttggcac atgaggagac
     1861 tacgatccac aacaccgttc aaaatcaggt agcgtcccaa accaaccaag tgggcttcgt
     1921 ccatcccgat attgaccttg cgagtcttca gtttagacaa cgtggcaaac atgccatcaa
     1981 tcaggtcata aaccttttct tcgccaatga gaagaatgtc ctctacatca cggagctcct
     2041 gcacttcctt gacaccccat ttgacaaagg ccgacaagtg ggccaaggtc tggatgcatg
     2101 gtacaaaggt catgtcaaac tgttgagcat aggcttcgat ttcctgcaac tcctctgctg
     2161 aataagctcc acggaaatag ccaaagtaag gctgcccttc aatctggtaa gtgtcttcca
     2221 tgtaaagttc aaaggttgag tagcccatga gagccaagac ctcaatcatc tgcttggcag
     2281 aagccacatt cagcaccgca tttcgagaac agtcaaccat gtaagccaaa tcttcgtaag
     2341 ctgcttgttc ctcaatctct actttatcag cttctgctag aactgttacc aacaaggata
     2401 aggcacgata aagttggtga ggtttgcggt aggtcaattg atagtgacct tcctcaccct
     2461 cgatagagat agaggcttgg tcagactgag tgacagccac ttccacatct ggtagagaaa
     2521 tgtgaccttt taaaacctca atagcttgcg tttgtttggg actaagtcct gtaaatctta
     2581 ccattgcttt tcctcctgta gccagttgac aagggcaccg tagagattgg catctgcgtg
     2641 ataggtgcag gtctggataa ctggtgcgac cgtgtattct tcgtaggcat cgacaaagtc
     2701 ttcaacagcc ttcttaacac cttggataaa atctggattt tgactgatag agccacccag
     2761 actgatgaca tctggatcga tcagatactg gatattgagc aagccttgcg tcagattgcg
     2821 gttcatgcgc tcaatggctt cttgacaaag agcattacca gctgcggcct cttggtaaat
     2881 cttgcgaccg tcccaatcag tatgaccaga tttttcaatc acgtatcgta ccatattccc
     2941 agttgatgct agttgcgacc agttattaag tttttcagca ggggcaaggg ttgtcatgta
     3001 gccaaattct ccacccagac cgtggcgacc tcgatgaagt ctaccattga taatcatggc
     3061 tccgccaatc cctgtcccaa tcacgacaca ggctgcattt tcaagctctg gatgagctag
     3121 tagttcactg agtccaacgc agttggcatc attttctaaa tggacaggta gctgataaga
     3181 gctaagcgcc tcataccaag aaaagccatg gatgtagggc accgcactga agccatcaat
     3241 cacacctgtc tcttgattga ccgcacctgg aacgctcata gcaatcccac tgtaatcctg
     3301 ttctgacaag cgttgatcta gccacgctag taaatcctcc aagttttcag gcgttgaaat
     3361 acttgtctta tccagtattt tcccatcagg agtcagactg gcaaacttaa tcccagtccc
     3421 tccgatatca atcgttgcaa tggtcattgt ttttaccata aaaaggggcg aatcagcagt
     3481 tagttcttac tttttcgccc atcctttctt ttgatgttta ctttttgaaa ttaaatttct
     3541 tcttttttga tgaattctgt acgaatctct tgtggagcca atagtcctga atgaactgga
     3601 tatagtcgct caagtaagtc aagaatggtt tgttgatgtt ctgatatgcg cacattttct
     3661 tgactcatat tatagtaacg gaggacatag ccttcttcat tttccgccac tttaaaggct
     3721 gttggacaaa cttgcggtat gctgagaaca gaatggctca agaggctacc agtcgcaacc
     3781 acgcttcctt cctgtctagc aagctgaagg ctggtaaacg gtgtctgcaa ggctttggca
     3841 cgacgatagg ctgagaagcg ttcttgggct tggtggcatt caagtgcaaa ctcgacttca
     3901 aactcccgca agcattgtgc ttctggcgtt gggaagtagc cccagtcacc tagctcacct
     3961 gatgcacgca aaatggtcac ggcaatggtg ttatccccaa ggatttcgta ttcattcaat
     4021 cccttgttgg atacagtcac ccctttttca tcgtcataca gactgacaaa agcttgttgg
     4081 tgttgaggat tttcagggtt ttcccatgaa gcagctggtt tgtttggtcg tgtcaccacc
     4141 tcatagatac tttcagaatc attgcttgga cgcgtgttat gagtcttgac caagagacgg
     4201 atacggtgat ccttggcagt gttagtaaag cgagtcttga agcggatttg tggattgtca
     4261 acgaagacag tcaactcagt ttccagagga atgtttgtca attcttctga ccgtccagcc
     4321 tcacgcttca taaactcgat gataccttgt tgctcttctt ctagcttttc atccgcactg
     4381 acaggcacgg tcaattcatg tttgagcaag attttagcat agcgatctgt gttttccaag
     4441 acctcgtggt ccttaagctc tgcaaagatt ggctctgttc cttttggttg gaaatagata
     4501 tactcatttc cgatgtcccc acggtcttca aagcggataa agtcttcata ggcttcgtga
     4561 gttgtcttat catagactgt gatgttgtca tccacactca ccgttacgaa tggtgtatca
     4621 atcactccgt tttggtaaat accctcacgg tgttcttgtt ctccttccag caattggaag
     4681 gttgtccaag aaagcggtgc taggtgaact ggaatggtca cgcgcacttg tcgagcaata
     4741 cgagcttggc ggaacttgtc ttttggtaaa tcgtattcaa aattagctcc gaggtcttcg
     4801 attgtagcct ctacaggacg accatccaag tcctccacac ggtaacttgg caagataaga
     4861 gcagccatct ttttgtagcc ttctgttggg tgcaattcct tgaaatcaca agtcgccaca
     4921 tcaatcactg tgctgacagt atcgacctta tcatgcaagc ctgtgttaat gacagtaaag
     4981 agatagtcac tttgagcctt atccgtagca attttaccct tccactcgtt gagcaaatta
     5041 cttttaacaa agtttcctac ttggttgacc ttggcaaaac gcgtttccat ctcgcggtga
     5101 acttcgtcca cgctacagcc acagatacta tcatgtggcg cattctgcaa aagtgttttc
     5161 caagcatagg tcaactggtc cttgtggttg tgtccaccag tgataatagt caagggttct
     5221 accacttgct ctaggaggtt gctattttct tggaaggctt gttttaggta aatgcgggat
     5281 gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct gactggtcaa ctcacctgta
     5341 acagttgata agagttcagg aagcgcacct tctacagctt gaacatattc atcaaaagaa
     5401 ctatgaacaa agattacatc cgggaagagt tcatttgcca cacgaatggc ttcgctcaga
     5461 tttttctgta caggctggtg gtcacagccg ttcatcatca accattggtt ggtcgaagcg
     5521 taggcacgca catctgacaa tttttgtttc cagaaggtca aggcctcatc tttgtcaact
     5581 gggatttcat tcccattact gtaccagtta gcaaagagaa tacctaaaac acgactacca
     5641 tccacaccct gccagtacat ttctgaaaac tgggatgtaa actgctcatc ttcaaggact
     5701 tggttgtcaa atccaatcgg cttcacacca cgaccaaagg ccgccacgtg aatgcctgat
     5761 ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg tatctggaaa gtagccaatc
     5821 tgggttgatt taccccattt ggcagcttct tgttgaccaa tcaaggtatt gcggacattg
     5881 gcttcactgg agatcaagta gtcatcctgc aagatgtaaa agggaccaat tttaagtttg
     5941 ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag ggcgaatttg taagtagtcg
     6001 tcaaggacaa tagtttgtcc atccaagtgg aaactcttga actcagggtc attttcaaag
     6061 agatcaaaga gattgtcaaa caattccacc aactgcatac gatggctttc aaaaggcaag
     6121 taccactcac ggtcccagtg actatgtgag ataatatgta caacaacatt ttccatgaag
     6181 taaaacctca ttctaaattt aaattttaac gttttaaatg taaacttgtg attctgataa
     6241 gaatcggttg agctaaagcg agccccttag cgaatatcca agtaatccaa gaccaactca
     6301 cagaacatca tgttagccca ggagaaccat tcacgagagt agagggtcgg atcatctacg
     6361 tggaagcttt cgtgcatgac acctgtacca ccatcgcagg caaccagctg atccagcaag
     6421 aattttttct ctgccttatc tcttgttgtc aatccttgga tagaaagggc gattggccag
     6481 atatagcgat agaaggtatg agaacttccg agaccgctag cgtattctcc ttggtagaag
     6541 tatggatttt cagagctcaa aatggtacgg cgagtagctt gatacacttc atcatcgacc
     6601 gaacagtagc ccagataggg cgcagctagt agacttggta catttggatc atccatgatg
     6661 ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct tttcgccctt gctgttggtg
     6721 gtgtaagcgt agttttcgat tccttcttgg atttcatcct gaagacgctt ggcatcagca
     6781 ataacactct ggctatcagc taggtttaat gctgcgaaga tttcttgcac ataacccaag
     6841 actactacag caaacatatt tgacggaatc aagtaactat actggcaaca gtcatcactc
     6901 ggacgaaaag ctgaccaagt catacctgtc actgcaaagt caggtccaaa gccatcattt
     6961 accaaggtgt cttccttacg gtccgtatct cggacaaaac gataaggaga gttcttgtgg
     7021 tcttgttcaa ctgtccatag atggagaatt tccttagtcg ctacgacaaa aatctcatca
     7081 aactgactag tctcgccagt ctctttccag aggagataag ccaactgcaa aggatagcaa
     7141 agtgaatcca cctcatactt gcgctcccag atccagccgt taaggtctgt gtgatcagtc
     7201 tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt tagcataggg atccttgagt
     7261 accaaggtca tctgacgttt gaccaaacct gcaatggtct gacgcaggag ggcatctctt
     7321 ttagctacat gaaggtaggg tctgagttgg gctgtcgaat ctcgaagcca catggcagga
     7381 atatccccag tcaagacaaa agttgaacca tcttctaaga tttcaaccgt attgtccaag
     7441 gtatcggtgt agcaacgctc gaaaacatcc acccactctg gatggtcctt agcccgctct
     7501 gctacttcat ctagccattc tctaacaatt tctttcgaat aaatcatcgt gcaattccct
     7561 ctttcaaaca agtttcattt tcagtatata gcttttgaga cagaaaatac atacacaaat
     7621 gatagtcatt tttctacaaa atagttatct ttaaaactcc ttttctaaag gccctctttt
     7681 tctgatataa tgtagaaaaa cagctaaagg aaagactatg aaaccactac ttgaaaccat
     7741 cgatacccgc tttggtactg ctagcaagca tgccttctct cggggaaata ccctgccata
     7801 cacaggcgtg ccttttggga tgaattattt tgtgccccag accagtgacc aggacggagc
     7861 ttggtttttt gatccgcatc tgcctatctt tcaggggatt cgattaactc accagcccag
     7921 tccttggatt ggggactact cttggctcct tctgacacct gtcaccagtc aactgggtgg
     7981 agacagcctc tttcaccgcc agtcttctta tgatatagat aaagcttgct tccagcctca
     8041 ctatttgaag ctcttttccc tgcgctatca aattgaaacc cagctcacac cgacttgcta
     8101 tggtgcttct attcgtttga atcaaaagca aggcaaagcc ctctccctct atcttcacgc
     8161 agcagatgaa ctgaccgtag agcaagtaga taagcggact ctggctctca gacaagaagg
     8221 caaaacagag accaataaaa atccactgat gctcttcact gccctgcaaa tgaacacgga
     8281 tattcttgct atcagccaag aagctggaga ctggcgaatt gacttagcaa gtagtcaaac
     8341 cgagatgcaa ctagccactt ctttcatctc tccttctcaa gcactactta atctacctca
     8401 agaagatttt gatagctgta aatcaagtgc ccaagcggat tgggaaaatc tcctccatcg
     8461 ttttgacatt atagagatag gagaggctga ccgaaccttc tttgaccact gtctctacag
     8521 actcttcctc ttcccacaga ctttttatga ggttgatgag tcagggcaag ccatccacat
     8581 ggatctggct actggtactg tcaagcttgg tatcctcttt agcaacaatg gtttctggga
     8641 taccttccgc accaccttcc ccctctttgc ccttatcata ccggagcact atcaacgctt
     8701 tttagaaggt ttcctcaata gctaccgcga tactagtttc cttccaaaat ggctggctcc
     8761 agatgaacgg ggtatgatgc caggtacact tttagacggt attatcgcag atagcgcctg
     8821 caaggacatg gcccccgacc tagaaggaga actcttccaa gccatgctcg aaacagccag
     8881 caaagccgac cctctcggca tcaatggccg ccacggacta acccaatacc aagaactagg
     8941 ctacctctct accgaccaca acgaaagtgt tagccatact ctagactatg cctatagtga
     9001 tttttgtatc gccagctgtg ccaaaaaact agagaacata gaaatcgctg aaacctacaa
     9061 ggctgcttca caaaattacc gccagctatt tgacgctgag acaggttaca tgcgagcacg
     9121 agacaatcaa ggaaactttc accctgactt ctctccttat agttgggggc gagactacgc
     9181 tgaatgctct gccattcaag ctactttagg cgttctccac gacatccctg gcttaatcca
     9241 acttatgggt ggaaaagaaa cctttagcaa ctatcttttg aaagcctgtc aagatgctcc
     9301 cctctttgaa acaacaggct atggttacga aattcacgaa atgagcgaga tggctactgc
     9361 tccttttgga caaatagcca tttccaacca gcctagtttc cacattcctt atctcttccg
     9421 ctacagcgat taccctgact acactgccct tcttatcaag acgctccgtc agaaagcttt
     9481 tcacccaagt tgggaagcct atcctggaga tgaagacaat ggtagtctct ctgcttggta
     9541 catctggtca gctctcggat tttatccaac ctgtccagga aaaccaagct atgacctcgg
     9601 aatccctctc tttgaccatc tacgagtcta cctcgctaaa gaagataaat ggctggatat
     9661 ccatactaaa caaaaccaca accattttaa ctttgtcaaa gaatgccgac tggacaaaac
     9721 actcgtatca actattcaac accaagacct cttaaaagct gaacaactaa ctttcaccct
     9781 cagctggtta ccaagtcact aataaccaaa agaacctttg catcgcgcaa aggttcttct
     9841 tttatgaaac ttgaacttga agttgatcca caagctgacc atccaccgtt aggttcagat
     9901 agaaatccaa ggttttatct cctgcgaaat acaaggttgg tagcgtcaga cttttttcag
     9961 tctcaccagc ttgaaacgca agaacttgaa tctcatcctg ataggcgaca ccatggacac
    10021 ctgtccccgg ttgaatcgaa atcttagcct ctaaagagga gctactttca ctacgttcaa
    10081 tcctaaaatg aagagtctct ccctttgcca cagctaggct tttttctgca aatgctagtt
    10141 cctgaacaac ttcttttttt gataacccag gagttttata aagggaaatc ttggtcagta
    10201 gaggcataga ttgtgcttcg gtaatcatca cgcgcacctt ctgtgcctct actagcggac
    10261 ctcgcaagag gcgcttatga ccaactgtga agcccctgcc aaattcctgc cagacaccat
    10321 ccacctctac ttgcacatgg aaagcagcga ttcgttgccc tagcttcaaa tcttctctta
    10381 actcaattac atcaaaagtt ttaggagaac ctaagtcgag ttctaactgg atgggcaagg
    10441 ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt caaatggcga caagcaaagt
    10501 ctgcggaaag agctggacca gatacctcag ctcccagagc caaatcttct ttatagagct
    10561 cattgcgata ggtcgcaaat tcataaagtc gttcaatatc ctttgcatca aagagcccag
    10621 cttgattcgg cggaatatta agcaagagtg gagttcctcg ccctactgag tgaaagtaga
    10681 tttcgaccaa ctcctcgaga gacttaggat cctgatcctc atggtagaac cagcctggac
    10741 ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc cgagggatcc ccgtgctgaa
    10801 gatagttcag ctctgcttct gttcctagtt tatcaggatt caccttttgc cacagtggat
    10861 cacctgcata ccctcgttca ttgccaatcc agcggatact ggtgccttct gttgaaaaaa
    10921 tcaagcaatc gccctgcagg tcacgagtgg tttcaaacca ttttttaaat tcataattaa
    10981 ccttttgcgc accctctcct ctggcaccat ccatccaaac ctcagcgaac ttaccagcat
    11041 tcccatagtt aggatttgat aagatttcct tcaactgagc cagataatag gcattgtagt
    11101 ccgcttctcg gtccacatga tagaggggac tatgggcatc ccacggtgac aggtagaccc
    11161 ccatatccat atcaaactct gtggcagctt gggatacttc aaggagcaag tcgccctttc
    11221 ctctcctcca aggactgacc ttaaccgaat aatctgtgtg agctgtcgga taaaggacaa
    11281 agccatcgtg gtgcttgacc accaaaatca actttttgaa gcccgtttcc ttgagcacac
    11341 gaacccactc acgcgcatcc aactgactcg ggttaaagcg ctcaggatcc tcctgtccag
    11401 tcccccattc ttggtcataa aaggtattag gaccgaagtg gataaaagct gctagttcat
    11461 ctcccagata agctagctga gtctgacttg gtaacggtcc atgcggtttg attttcttca
    11521 tcgttatata tctccttctt tagcaacttc tcttgttcac aaggttatcc acaggttgtg
    11581 gataataaac catgatctaa cagccagctc tttccaactc caactggtag gctcaggatt
    11641 tttctcctca atattccctc ttcaaacagc tctgtcatat ggttctgcta acacctctca
    11701 gaatgctact ctccataatt attctcaggc ttctttcagg tcattgtgtg aagaccattc
    11761 actctccaga cttttccaca gattgtgaat aagtgattat tctaagctat cacctcgtcg
    11821 actataacaa aaaataaaaa gagggtcaat aagataatta tctcttccta aatactaaga
    11881 aaagattcta taatttgtac aattgaacaa gaaatgcttc tccaaaatct atcttcaaaa
    11941 gaatgttgca tctttttatc ctttcacaca aacatttctc tttatacaga tccaagtgat
    12001 aaccagatga taattggaca ctttttggtc atttgtatat tttttgaaaa attttttaaa
    12061 aaaattttat atccttttta tagaagttta tgcatttgta tctatgtatt ctatcctatg
    12121 ttatgtataa taacataaaa ttgtgctaaa catcataatt tatattattt tccgagaaat
    12181 tatagccatt gacattacct aggaattgcg ttataacata catgtaagcg gtacccaaaa
    12241 tggtgccaag tcaaaatttt taaggaggaa aatacatgtc ttctcatcca attcaggtct
    12301 tctcagaaat tgggaaactg aaaaaagtta tgttgcaccg tccaggcaag gagttagaaa
    12361 acttgttgcc ggactatctt gaaaggcttc tttttgatga tattcctttc ttggaagatg
    12421 ctcaaaaaga acatgatgca tttgcccaag ctcttcgcga tgaaggaatt gaggttctct
    12481 acctagaaca actcgctgct gaatcattga cctctccaga aatccgcgat caatttatcg
    12541 aggaatactt agacgaagcc aacatccgtg atcgtcaaac caaggttgct attcgtgaat
    12601 tgcttcacga catcaaggac aaccaagaat tggttgaaaa aacaatggct gggattcaaa
    12661 aagttgaatt gccagaaatt cctgacgaag ctaaagatct aactgactta gttgaatcag
    12721 attatccatt tgcaattgac ccgatgccaa acctctattt cactcgcgac ccatttgcaa
    12781 caattggaaa cgccgtatcg cttaaccaca tgtttgcaga cactcgtaac cgtgaaacac
    12841 tctacggtaa gtatatcttc aaataccacc caatctatgg cggaaaagtg gatttggtct
    12901 acaaccgtga agaagatacg cgtatcgaag gtggagacga gctagttctt tctaaagacg
    12961 tccttgcagt aggtatctct caacgtacag acgcagcttc tatcgaaaaa cttttggtca
    13021 acatcttcaa gaaaaatgtt ggcttcaaga aagttttggc ctttgaattt gctaacaacc
    13081 gtaaattcat gcacttggat actgtcttca ctatggtaga ctatgacaag ttcactattc
    13141 acccagaaat cgaaggcgac cttcacgttt actcagttac ttacgaaaac gaaaaactta
    13201 aaatcgttga agagaaaggt gacttagctg aacttcttgc tcaaaacctt ggtgtagaaa
    13261 aagttcattt gattcgttgc ggtggtggca atatcgtagc agctgcgcgt gaacaatgga
    13321 acgacggttc taacactttg accatcgcac ctggtgtggt agttgtttat gaccgcaata
    13381 ccgtgaccaa taagattttg gaagaatacg ggcttcgctt gattaagatt cgcggaagtg
    13441 aattggttcg gggccgtggt ggacctcgtt gtatgtctat gccatttgaa cgtgaagaag
    13501 tgtaatcgct gttcggcatt cgtcaataga aaatgtaaaa aatagaaaga ggaaataata
    13561 aaatgacaaa ttcagtattc caaggacgca gcttcttagc agaaaaagac tttacccgtg
    13621 cagagttaga ataccttatt ggtctttcag ctcacttgaa agatttgaaa aaacgcaata
    13681 ttcaacacca ctaccttgct ggcaagaata tcgctctcct atttgaaaaa acatctactc
    13741 gtactcgtgc agcctttaca actgcggcta tcgaccttgg tgctcaccca gaatacctcg
    13801 gagcaaatga tattcagttg ggtaaaaaag aatctactga agatactgct aaagtattgg
    13861 gacgtatgtt tgacgggatt gaattccgcg gattcagcca acgtatggtt gaagaattgg
    13921 cagaattctc aggcgttcca gtatggaacg gtctaactga cgaatggcac ccaactcaaa
    13981 tgctcgctga ctacttgact gttcaagaaa acttcggtcg cttggaaggc ttgacattgg
    14041 tatactgtgg tgatggacgt aacaacgttg ccaacagctt gctcgtaaca ggtgctatcc
    14101 ttggtgtcaa tgttcacatc ttctcaccaa aagaactctt cccagaaaaa gaaatcgttg
    14161 aattggcaga aggatttgct aaagaaagtg gcgcacatgt tctcatcact gaagatgctg
    14221 atgaagcagt taaagatgca gatgttcttt acacagacgt ttgggtatca atgggtgaag
    14281 aagacaaatt cgcagaacgt gtagctcttc ttaaacctta ccaagtcaat atggacttag
    14341 ttaaaaaagc aggcaatgaa aacttgatct tcctacactg cttgccagca ttccacgata
    14401 ctcacactgt ttatggtaaa gacgttgctg aaaaatttgg tgtagaagaa atggaagtaa
    14461 cagacgaagt cttccgcagc aagtacgctc gccacttcga tcaagcagaa aaccgtatgc
    14521 acactatcaa agctgttatg gctgctacac ttggtaacct ttatattcct aaagtataat
    14581 tttagataat aaaccgtcta ccaacagcta tgagggctgc gactaatagc tttagtccgg
    14641 tcctctttta tgtaatggta atctattatt tcttataaaa tatgtgaaaa atcattaaat
    14701 tgaaatctaa acgcattcta ttgagtgtga taaaggagaa tttatggcaa atcgtaaaat
    14761 tgtagtagct ttgggaggaa atgcgattct ttcttctgac ccatcagcaa aggctcaaca
    14821 agaagcttta gttgaaacag ctaagcatct tgtaaaattg attaaaaatg gagatgatct
    14881 gattatcact cacggtaatg gacctcaagt tgggaatctc ttgctccaac atttggcatc
    14941 agactctgaa aagaaccctg ccttcccact cgactcactt gtcgctatga cagaaggtag
    15001 catcggtttc tggttgaaaa atgctttgca aaatgctctc ttggatgaag gcatcgaaaa
    15061 aaatgttgcc tctgttgtaa cgcaagttgt cgtagataaa aatgatccag cttttgttaa
    15121 cttgagtaaa ccaatcggtc ctttctattc agaagaagaa gcaaaagcag aagccgaaaa
    15181 aagcggagcg actttcaagg aagatgctgg ccgtggctgg cgtaaggtcg ttgcctcacc
    15241 aaaacctgtt gacatcaaag aaattgaaac catccgtact cttttaaata atggtcaagt
    15301 cgtcgtagct gcaggtggtg gcggtattcc cgtcgtcaaa gaaaacaatg gacatttgac
    15361 tggtgtcgaa gcggttattg ataaagactt cgcttcccaa cgtttggcag aattggttga
    15421 tgcagacctc ttcatcattt tgacaggtgt agattatgta tttgttaact acaacaagcc
    15481 aaaccaggaa aaattggaac atgtgaatgt tgcccagctg gaagaatata tcaaacaaga
    15541 tcagtttgca ccaggtagca tgcttccaaa agtagaagca gctatcgctt ttgtcaatgg
    15601 tcgtccagaa ggaaaagcag ttattacttc ccttgaaaat ctaggcgcct tgattgaatc
    15661 tgaaagcgga acaattattg aaaaaggata agttgtttta ctaataagat gtattctatt
    15721 tctagtatct ttatatcaaa ttagaaatta ttcttgaaaa catgtacaat atttcaaaag
    15781 atactagttt tagactttaa tatggtaaaa caaatataaa tagaaagcgt tttcttgaat
    15841 gtttatttaa gaaagtagtt ggttttttac actttgttag acatcaggag gaaaaacaaa
    15901 tgagtgaaaa agctaaaaaa gggtttaaga tgccttcatc ttacaccgta ttattgataa
    15961 tcattgctat tatggcagtg ctaacttggt ttatccctgc gggggccttt atagaaggta
    16021 tttacgaggc tcagcctcaa aatccacaag ggatttggga tgtcctcatg gcaccgattc
    16081 gggctatgct aggtactcat ccagaggaag gttcgctcat taaagaaacg agcgcagcga
    16141 ttgatgtagc cttcttcatc cttatggttg gtggtttcct tggcattgtc aacaaaactg
    16201 gtgctcttga cgtagggatt gcctctatcg tgaagaagta taagggccgc gaaaaaatgt
    16261 taattttggt actgatgcct ttgtttgccc tcggtggtac aacttatggt atgggggaag
    16321 aaacaatggc cttctatcca ctccttgtgc cagttatgat ggccgttggt tttgatagcc
    16381 tgactggtgt tgcaattatt ttgctcggtt ctcaaatcgg ctgtttggca tctactctga
    16441 atccatttgc gacaggtatt gcttcagcga ctgcgggagt tggtacaggg gacggtatcg
    16501 tacttcgtct gatcttctgg gttaccttga ctgctcttag tacttggttt gtttaccgtt
    16561 atgcggataa gattcaaaaa gatccgacta agtcactggt ttatagtact cgcaaagaag
    16621 atttgaaaca ctttaacgta gaagaatctt catctgtaga atctacactt agcagcaaac
    16681 aaaaatcagt tctcttctta tttgtgttga cattcatctt gatggtattg agcttcattc
    16741 catggacaga ccttggcgtt accatttttg atgactttaa tgcttggttg actggtcttc
    16801 cagttattgg taatattgtc ggttcatcta cttctgcact aggtacttgg tacttcccag
    16861 aaggcgcaat gctctttgcc tttatgggta tcctgattgg tgttatttat ggtcttaaag
    16921 aagataagat tatctcttcc ttcatgaatg gtgctgctga cttgctcagt gttgccttga
    16981 ttgtagcgat tgctcgtggt attcaagtta tcatgaacga cggtatgatt accgatacaa
    17041 tcctcaactg gggtaaagaa ggcttgagcg gtctatcttc acaagtcttt atcgttgtaa
    17101 cttatatctt ctatctacct atgtcattct tgatcccatc ttcatctggt cttgccagcg
    17161 caactatggg tatcatggct ccacttggag aatttgtaaa tgtccgtcct agcttgatta
    17221 tcactgctta ccaatctgct tcaggtgtct tgaacttgat tgcaccaaca tctggtattg
    17281 tgatgggagc tcttgcactt ggacgtatca acattggtac ttggtggaaa ttcatgggca
    17341 aactcgtagt cgctattatt gtagtgacca tcgcccttct tctccttgga accttccttc
    17401 cattcctata aaatagtgag tgaggtgatt ccatgaaaat agatataaca aatcaagtta
    17461 aagatgaatt tcttatatca ttaaaaacct tgatttccta tccttcagta ctcaatgaag
    17521 gagaaaatgg aacacctttt ggacaagcaa tccaagatgt cctagaaaaa actttagaga
    17581 tttgtcgaga cataggtttc actacctatc ttgaccctaa aggttattac ggatatgcag
    17641 aaatcggtca gggagcagag cttctggcca ttctctgtca tttggatgtt gttccatcag
    17701 gtgatgaagc agattggcag acaccgccat ttgaagcaac tatcaaagac ggctgggtat
    17761 tcggacgtgg tgtccaagat gataaaggcc cttcgctcgc agctctctat gcagtaaaaa
    17821 gcttgctgga ccaaggtatt cagttcaaaa agcgcgtacg ctttatcttt ggtaccgatg
    17881 aggaaaccct ctggcgctgc atggcacgct acaataccat cgaagaacag gccagcatgg
    17941 gctttgcacc tgactcatct tttcctctga cctatgctga aaaagggctt ctacaggtca
    18001 aacttcatgg ccctggatcg gatcaactag agcttgaagt aggaggcacc tttaacgttg
    18061 taccagacaa ggccaactac caaggtcccc tctatgaaca ggtttgtaac gatctcaaag
    18121 aagctggtta tgattaccaa tccactgaac aaaccgtaac ggttctcgga gtgccaaagc
    18181 atgctaagga tgctagtcaa ggtatcaatg ctgtcatccg actagctacc attcttgctc
    18241 ctctccaaga acaccctgct ctcagctttc ttgcaacaca agcaggtcaa gacggcacag
    18301 gaagacaaat ctttggtgat atagcagatg aaccttctgg tcacctatcc tttaatgtcg
    18361 caggtctcat gatcaatcat gaacgttctg aaatccgtat tgacattcgg actcctgtct
    18421 tagctgataa ggaagaacta gtagagttgc ttacaagatg tgcacaaaac taccaactcc
    18481 gctacgaaga gtttgactat ctagcgcctc tatacgtcgc aaaagacagt aaactcgtta
    18541 gcacactgat gcaaatctac caagaaaaga ctggcgataa cagtcctgct atttcatccg
    18601 gtggtgccac ttttgctcgc accatgccaa attgtgtagc cttcggcgcc ttattcccag
    18661 gagcgaagca gacagaacat caggcaaatg aatgtgccgt tctagaagat ttgtaccgtg
    18721 ctatggatat ttatgccgaa gccgtctatc gacttgcaac ttaatcaggc aactgtttct
    18781 accaaaaaaa aatcgaccga ttaatgaact gcaccccaaa agttagacag aataaatcta
    18841 acttttgggg tgttttatta tgaaattgag ttatgaagat aaagttcaga tctatgaact
    18901 aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga tttggtgtgg atgtttctgg
    18961 tctaaagtca tctgaatctt tgagatgagc tttataaatc gcttttttca gtttttgcac
    19021 tggtgtttcg ataaactcaa actttttagc cgtggtattg cctgatttta tagtatattg
    19081 aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg
    19141 atcgatttgt cctgttctta tttcatttta ctatatttga gccacttcgt ctttaacggc
    19201 tttattcata agctcttgta atttttcttt actatcaatt acttctgatt ttccgttgta
    19261 atttattgta ataggtttta acttacctaa tttctcgaca cgctcattaa tttgatcttt
    19321 tttgaaggct gcatatgttt ttcctaagat tttttcgaaa atatatttat cagatagcgg
    19381 tttgccttct tcttcagctt ggtttttgta ttgatttgaa acataaggaa caaatccttc
    19441 atagtaacct aatgctccca taagttcaaa agcttgtttt ctaattcaaa ccattgcaac
    19501 tcagatttca gcttttcaga taaatcctgc tcatccaaat aatgacttga aattagtgct
    19561 gaactcgttt ctgtatcctg tacaggctga tcacccatac cagcaaaaaa taaactcgtt
    19621 cctagcaaga ccgaacaagc tcctattgca tatttcctca aagaaaaacg ctgctttctc
    19681 tcaaattgaa attctttcat cccatctccc atcattcatt attactgtat attttgtata
    19741 tcagaaatag tttgtattca caaatctttc tagttattcc cttatcattc ctaattaagg
    19801 gagataacat acaataattt ttagttaaat gtatatcgat gttttttgtt tttcttaata
    19861 aacgcaatac aaaaagagcc tgttgccaag ctctttgtac tcaatgaaaa tcaaagagca
    19921 aactaggaaa ctagccacag gttgctcaaa acaccgtttt gaggtagtag ataagactga
    19981 cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat
    20041 ctatacggca aggcgacgct gacgtggttt gaagagattt tcgaagagta ttagtctatt
    20101 atttcttctc agcgcgaagg gctgacaaga tttgtgttcg gatatcatcc acaccatttg
    20161 gagtatttgg taaaaagata gtttgatttc ctttagaggc aaaggtattc aaggtatcca
    20221 aatactggtt ggtcaagagg atagacatga tttgttcttc tgtcatgcca acattggctt
    20281 ccttgagttc ggtgatagac tctgccaatc catccacaat cgccttacgt tgttgggcaa
    20341 tccccacacc atgaaggcgg tctttttctg cttctgcttc agctgcagtg acaattttaa
    20401 tcttgtcagc ttccgccaat tcttgtgctg cgacccgctt acgttgcgcc gcattgattt
    20461 cattcatgga ttgcttaact tctgcatctg gttcgacctt ggtaatcaag gttttcacga
    20521 taatgtagcc gtaagtggtc atttcttctg ctacttggtg ttgaacctca agggcaatct
    20581 catctttttt ctcaaacaat tcatccaagg ttaattttgg aacagaagag cgaagagcat
    20641 cttcgatata agatttaatc tgagattctg gacgtatgag tttatagtaa gcatctgtca
    20701 cgctctgctc gttgacacgg tactgagtcg ctacattcat cataacgaac acattgtcct
    20761 tggtcttagt ctcaaccaca atatcacttt gcaacaagcg caactgaatc cgtgctgcaa
    20821 tcgagtcaat cccaaaaggc aagcgaatat gaataccgct attagcaacc ttttggtatt
    20881 tcccaaagcg ttcaataatc gccaccgact gctgacgaac cacataaact gtactcagtg
    20941 tgactatcac caataggagc acacaaacaa tcagaaaaat catgaaaaat attgccataa
    21001 tggaacctcc acaagtattt ttctagtatt atagcacatt taaagaaggc tgtgccgttt
    21061 ttactgcgat ttttcctgaa atgtcaataa ttagaggtga attgtcctat tgtcgtccaa
    21121 tctcttgcta aaataactct ttataaaagg caatcgtttc ttctaaggtt ggcataaatg
    21181 gatttcctgg tgcgcaggca tcaatcaagg cattcttaga aaggtattca aagtcgaaat
    21241 ctttttcttc aataccaagt tcagtcagtt tcttaggaat acctactgtc tcagaaagct
    21301 tctcaatctc aacaatcgca taatcggcac attcttgatc tgatttacct tctacatgaa
    21361 gtcccaaggc tttggcaaca ttgcggaaag cttctggtac acgtttagca ttttcacgtt
    21421 ctataactgg tagcaacatg gcacagcaaa caccatgtgg caaattatat actgcaccga
    21481 gttggtgagc cattgagtga acataaccaa gaccagcatt attaaagctc ataccaccaa
    21541 ggaagatggc attgaccata ccttcacgcg cttcaatatc atgtccattt tctacagcac
    21601 gaggaagata ttccttgata agctcaatag caccaataga cagtttcttg gttacatcat
    21661 aagcaccagg tgttaccaaa gcttcaacag cgtgagtcag agcatccata ccagtagcag
    21721 cagtcaggcc tttaggtttg gaaagcatga gttccgggtc attaacagag ataagagcaa
    21781 ggctattctt gtcaaccatt accatcttaa ccttgcgttc ttcatcagta atcacatagt
    21841 taatggtaat ttctgctgat gtacctgccg ttgtattgat agccacaact ggcaagcctt
    21901 ttttagcaga cttatgaagc ccttcataat cctgtggttt tccaccattt gtagccatga
    21961 tagaaataca actagctgca tcctgtggag aacccccacc aagactgatg ataaaatcac
    22021 agccatgttc ttgcaaagca gctaccccat ctgtgacatt cttacaagta gggtttggct
    22081 ctacatcgct aaagatgaca tattcgattc cttctgtatc cagtggtttt aaagtcttag
    22141 gtaaaatatc actgccttcg atgtacttat ctgtaaccaa aagtgccttt ttatagccaa
    22201 gttccttgat ataaggaccc acttcattta caacaccttt tccaataagg ttgactgccg
    22261 gaacataaaa tgtagccata taattttcct cctgcgcctc cgcgctatct atttaacatc
    22321 attatattac tttttgtatt cgtttttaat tatttgtgaa ttgtttaaca aatcttttta
    22381 aaaggatagg agggacgtaa gttcacctcc tatataaaca agttttattt atgtagtggt
    22441 cccaacaact gacatgcacg atagtctgct gattctagat cttctgttcc aaataaggac
    22501 caatttttag gtctaaagat atcttcctca ggtacattat gcatattgac aggaattctc
    22561 aacatagaag ccaaggtaat caagtctgct ccaatgtgtc catatgttat ggctccgtga
    22621 ttagctcccc aattattcat gacgtcatag acagacttga aagcaccttt tcctgtcaaa
    22681 cgtggagcaa accaagtagt tggccatcct ggatctgtac gattatctaa agtatggtga
    22741 acatcttcag gaagttcaag tgtataacct tctgcaattt gtagcactgg accaacccct
    22801 tttagaagat tgagacgtac cattgttact ggcatatccc ccttcgtcaa gaaacgagtt
    22861 gagaatcctc ctccacggaa gtattcgcgg tttgctggtg ggaagtctgt attttcaagc
    22921 atagcctgca cttcactttc atccaactcc cagaatggtt tcataacagg tttgccatct
    22981 cgagtagctt gccctgtacc atccaatgta caagaaccag agttgattag atgtaagaag
    23041 ccagctgcag cacgaccctc taaagtatgt cccgttacac gtttaacagc ctctggactc
    23101 caataagtgc gcacatcagc aaagatttgt ggagtatttg ttaatagata attaaagagc
    23161 atagacacac catttagtga atcattctct gtcgcaaata caaatggttt tcgaatacca
    23221 ttccagtcaa actgagtatt gaggaaagtt tccataaagt ccccatttgg gaaatggtct
    23281 gtccactggc gttgaccttg gaaaccagct actaaagcat ggtgaccaac tgcttcttcc
    23341 tcaaaaccaa gttcagcaag tcttgggtta ccaaccatta agtcacgtcc aatcatgaac
    23401 atcttaataa caaattccca ttgtttttct ttctcttctt tagaaagaat caaatcctca
    23461 cgatttcggt caactccttc tttgatatgt tcttttaccc aaaccatagc acgttcaaac
    23521 tcttctgggt cgtaaatacc acggtccata cggcgcgtga actccgtcat atctaccgat
    23581 tcatttcgca ttcctaagta ttcttggaag aaatctggat ttacaataga accgccaatc
    23641 cccatcgaaa cactacccat tgataggtaa gcagtgtctc tcatcaagcc agttgcaaga
    23701 gctgcacgcg cataacgtaa aagtttttct ttgacatctt ctggaatagc tgtatcatta
    23761 gcttcctgaa catctctacc ataaatccca aaggctggaa tccctttttg agcatgtgaa
    23821 gctagtacag ctgcaagata gacagctcct ggacgttctg tcccattaaa tccccaaata
    23881 gcatgaggaa tatctggaga catatccata gtttcactac cataacacca gcatggtgta
    23941 actgtaattg ttgcgcaaac atttgatttt ttaaacaact catgggaagc tgcagcctct
    24001 ggaacacgac caatagtaga tggagaaatc acgcattcca caggttcccc atctggatat
    24061 ttcaatgtgc ttgaaatcaa atctgccaca cttttagcca tgttcattgt ttgcacttca
    24121 agtgattcgc gtacaccttg acgacgacca tcaatagtcg gacgaatacc aatacgtgga
    24181 tgttgaatca tactattttc ctcttatttt tctgtttctt tcatactacc atcgccatta
    24241 tatttacggt agcctgggtg acgacctgta accttataat tttctcgcat tgagaataga
    24301 cgttctaaag tcggacgagc aatttcttgc tcctcaatgc cctttgtaga aagtaacatt
    24361 cttccgtgga aggttgtctt tgcgactaat tctaaagttt ccatacggta gtatgctgta
    24421 attacatcgc ttccgacagt cagagctcca tgattttcta atagcatgac atcatgatcg
    24481 ggcagataag gtgtaattgc ttctggcact tccattgtag acggaactcc aaatggcgtt
    24541 ataggaattg cccctaccac aatcgcgctc tcaattagtg aataagtatc taaaggaatg
    24601 tgtgcaagag caaatcctgt tgcaatcggt ggatgcgcgt gaacaactga acggacatcc
    24661 tcacgttctt cgtagcacca aatgtgcatt ttaatttcac tagaaggaca gtaatcacct
    24721 tctgcttcta aaatctctcc tttaagattt aacttcacca gcttttctgg tgtaataaaa
    24781 cttttgctga taccagtagg tgttgcaaga atggtatcct catctaatcg aacagataca
    24841 ttcccatcgt tagcagcaac ccaaccaagt tgccacatct tatgacaaac atcacaaatc
    24901 tgttcacgaa ttaatttttc atcttgagac ataaactcac tcctttctaa aaatgaagtt
    24961 cgaattcaag atttccgtta ctgttaatgg taatagtaac catatgattt ttctgatcaa
    25021 aattgagaga tggctgatca taggaattat ttgttcctga taatgaatga atagtaggaa
    25081 gtttatctat acctcttaat actatctttg taaccctttt ctctccaaac tgagtatctt
    25141 tgatataatg ttcttcaatc cacttaatcg cacctttctt ggtcaattgt ggtagtttct
    25201 ttgcctgatt tgcatcttga gcattagacc atagtgaatc tttatttgtt ctaaaattat
    25261 ttaaattcac tttcaatcca ttacttattc tctcaaaaat accataggta tgaggttcaa
    25321 attcaacatc catttctaaa gaattaaatt ttaatttccc agtctgttta acattctcat
    25381 ttaccttgta attatagaca aaccatctat tatctaattt ctgagcaaag atatctcctt
    25441 cataattcat aggatacagc ttatttaagt attcttttct agcctgagta gagctaaatt
    25501 ctggagaagt gatttcctta atctgaatac ggctaccaga aacagactct ttcaatttat
    25561 ctgtttttaa aacacctgga atagctggaa taacattata acgaccagtc atgtataatg
    25621 gagtttgttc tctatcagta tttacgttta caaagaactt accatttcct ttatttgaat
    25681 agtctccatg tatgaatact tttgtatcct caagtacctt ttctttggat ggtgctggat
    25741 gcgctattac atatctaaaa aattctttta ttacttcgct aaagagtaag ctttctttat
    25801 tatttacacc ataggtataa gctgggtgtt caaaattata aactacacct ccattaaggt
    25861 aaacccctaa agcttcttct cctagcatag actctggttc agtcaaccat tgtctatctc
    25921 cttgactttt tccgatatta ccacttgcaa acagtttcca tttacctgtc tcataccact
    25981 tccaagtatc catcaaacca ccccattgat aagtatgatt tgaaagccaa agtcccttca
    26041 tataactttc tgtagttgaa tcatttccct cagcagcagg tgtatttttg aacatgaaaa
    26101 taaggttctt ccagtactta tcaacagatt tctgaaatgc tatcttaccg ttttttccaa
    26161 atgctttttc tattgcagaa ccattatttt gttcagccca tataaaatat cctccatttt
    26221 tagctgatac ttttaagtaa tctgccgcct tattttcaat atcatttgcc caaatccaat
    26281 aattctctgt actgaaaata ccatgcaaat ttggatattt ttgatacatt ttatcaatcc
    26341 agctggtact taaccaatgt gccgaagtat aataaggcat attaccagca gtgtaaaccg
    26401 tcagaataac tggaattggt tcattttttc cagtcttagg atttacatat ttcgctgctt
    26461 cttctaacat atgttcataa aaatctctag cagctccatc tcttttagta agatcatctg
    26521 gatgtaactg tataacagta tatggtttta agtcatctgg tatattctcc cacttacctg
    26581 ttaatgtatc tcctccccaa aaagtatatt tcccttggtt aaactcttct ccgttagcat
    26641 ataaaggcat cataagtaac ggatgttcat tattaatttc acgacgttta tcaacttctg
    26701 accaatcatt aggattctta aatttaccat ttgccataaa caaggctcca cctaaaacca
    26761 attcgtcagc ccatgtatgt ttccctgaat atgatttaag ttctattgtc tgtgtatctt
    26821 tgggaatttc aacatcaacc agaaatgccg atgtatcata cttaattcct tttggatatt
    26881 ttgaatctga tgagtaaatg actttaccat ccgcaacaac ttcaaatttt tgaatatctg
    26941 cgtaatctga atttaaatga ttggcgctcc tatcaattcc gacataggaa ataaatcttg
    27001 taacattagc acccgaaaca tcatatttta tactagacgg gttgcttgct acagttccca
    27061 atcccttatt aaattcgact tccttaccgt caattagtaa ttttatttta ttattagacc
    27121 cgttattacc aggtgtaaac ggtttatctt tctgaactgt ttttgattta tcgtcatcac
    27181 catgagtagc atcaacccat tctaaatcag aaagatatac tcctccatta attcctttat
    27241 taagaagatc tggagttata gtttgagtac taacagtttt aataagttta gcatcagcaa
    27301 atacaacctc atcaccccat gtatgttctc ctgcgaatga ttttaaggat atttttttag
    27361 cgttttgtgg aattgtcaca ctaataaatt gtgcctgggt attatatctg aatccttctg
    27421 gattagttac actactagaa tagacaacct ttccatcaat ttctatttct attctatcca
    27481 ctactgcatg gtctgatcta gaactattag cactttgatc aattcctata taagtttcaa
    27541 atttttcaaa cccttgaccg ctgatatcat agctgattac tgatggagaa tctgcgactg
    27601 ttcctattcc tttatcaaaa tatttaactt tatcatcaga agtgagcaat gaaatcttag
    27661 tatgctctcc tttatttcct gttgtaaatg gagcatcttt ttgtactgtt tttgttttat
    27721 ctatatcacc atgagttgca gaagaccaat ccatatctga aagatatgtc atctctttat
    27781 caatttcttt atctttagta ataagttttt ctaagttatt ccctgttact ctagcagttt
    27841 cagtactagc tctgttatta gaattacttt gaactacatc tgcataaacc aaattacttc
    27901 ctaaaaaact tgttaaaaca gccgtagcta ttaaaatctg ttttgctatt tttttacttt
    27961 ccatttttat ttcctcaata tttacataca acttcttcaa taacaaataa ttttgtaaga
    28021 tattctggaa cacaaagtgc taaattactt aaactgactt ttattccagc attcattaat
    28081 tcatctccat aaaagaactc atcaaatcta gagacggaat agcatttatc tttatctaaa
    28141 ccactaaaat aaactcttgt ataacctgga ttcaacttac tattcaattg agcatacaat
    28201 aaaatcgatt ggcatttatc ttttgaaaca acttgccaac tagcagaatc acaactaaaa
    28261 ggactgttta tcctatagaa atccccatat tgaaacaatg aacgatattt tttataaaac
    28321 tgaatttgtt ctctcacttg ttctttttct tctaccgaca atctcgtaac atctaattca
    28381 taaccgaaag aactaaaata agctacattt gtcctagtgt ccaaactcgt ttgtcttcca
    28441 ctttgttcat ttggagaaat agaaacatgg gctgtcatca ttgatggaga atatccataa
    28501 gaagttccat gctgaatttt caatctttct atcgggtccg tatcatcact cgtccacgct
    28561 tgcggtgcat aatacataag tcctaaatca aaacgtccac cacctgaaga acaagattca
    28621 aatagaactg aagggaactt agttattaaa cgatctaata actgataaag acctaagata
    28681 tatcgatgac caaattccat ctgctgttca gaatcaagtt caatactata aatatctgtt
    28741 atatgacgat tcatatccca tttgatataa tccagatttg ttttgattat gattttagaa
    28801 atagaatcaa aaaggtaatc aacaacttcc tgtctcgtca aatccaacac atattgattt
    28861 cttcctactg acttctctct gtctaacaaa tggatagtcc aatcggcatg attcttgtac
    28921 aaatcactat caatagaaat catttcaggc tcaaaccaca aaccaaattg taaacctatt
    28981 ttgtgaattt catctgcaag aaatccaata ccttcaggaa ggcgacttct atctgttacc
    29041 caatcaccca gagaactttt gtcatctttc ctatgaccaa accaaccatc atccagtaca
    29101 aataattcta tccctaaatc tttagcagcc tttgctaaat ctaaaatttt ttctgtactc
    29161 aagtcaaaat aaaatgtttc ccaactattg agtattatag gacgactagc ttgagaaaaa
    29221 ttaggattaa ctaaatgatg tcgataaaaa tctgatagtt gttggctcat ctgattcatc
    29281 ccttgatcag aatagatcac aattgcttct ggtgtcacaa aactttcggc aggatttaat
    29341 aaaaaacgaa attctactgg atttattcct accgttactc tagcggtgtc aaaatggtca
    29401 acttcaatca tattttgaaa atttccagaa tagataaagt taaaaccata aacctcacca
    29461 ctatgctctg tagtttccct ccttgatagc ataaagaaag gattttgctg aggacttgat
    29521 gagtatctca agctatctat tgcttgaata cctggtctaa gcgaagttct atataactga
    29581 cgttccctca gccatgctcc agaaaattga ataaagtcat attgactatc aggtagatct
    29641 agctgtaagc tcattgcttt caaaagagtc aacttattat tgctattatt taaaaattcc
    29701 gtatttctaa ctaagacatt gtattccgga aaaattgtgt aatttagtct aacagttaaa
    29761 tctaatatgg aatctgttaa aataatcgtt aatgtttcca cacactgacc aatatcatca
    29821 aatgttgaag gtagagagtt aagacgattt ttcccttttt caagttcaaa accttgatat
    29881 tttagtgtcg ttatcctact accattcatt ccttgaactt gaaaggctgg atgccgaaaa
    29941 tctcctttcc catatgaaga atattcattt tgtatcatag actgttgaat atcctcaaat
    30001 tcttcagaaa aagatacttc aaatcctctt ttttcataag ccatcaattg gttataattt
    30061 tccttgacat gaatcctttt cccaaaatgt agatgttgaa gttccccatt ttctaaaatt
    30121 ctaaaaatat aactactatc tttcattgcc aaatgaaaaa cggtctcgtc cttattaata
    30181 taaatcgtca tctctacctc acaatttttt ctttacttct tcagtatcac gatagagtac
    30241 ggtgccaatt ctatctcatc ttcttgaata gtaaaatctc caattactct ggtaaaattc
    30301 tctatcgaaa gattctctat ttttattttt tgtttaatct gagcaggatt tctcagagag
    30361 agaatttcag tagaagtctt ctgattgtga cacttataac cataaatttc aaatttttca
    30421 ggacttcctc ctattttttt actatatttt agtgtttgat aattctcctc tatccatttg
    30481 acggcacgag cattggcttt ccagcgttct tcatcaaaca tatcaaaaga atagtgaaac
    30541 tcccaaaaag cattccctct tgttgaaata aataatagat aagcttcaaa atctggtatt
    30601 gatgcaaaca tttgatgatc catgtaccag gtatttgcac tgacagcata gattggttca
    30661 tgattataaa tcgaccacat aggtaactgt atctcacgtt tttccaaaaa ttcttgatac
    30721 tgaatatctc ggtaagtaat catacgattg atatcattac ctgcattctc tgtaaagcct
    30781 acatcttgag atatttgaat ccataaacta ttgacccact gtaaaaacca tggactagga
    30841 tttacataag aagtcaagtt taaccaacaa tcttttcctc ctctctcctt tcttagatct
    30901 atcaacagtt gaattaagaa ctcataaacc gctgtcatgg tatacatacc gtgcggtcca
    30961 ctcttatcag gtttgtcagg ttgaagtaac caaccatcaa ttttccaata gctgatatcg
    31021 aattcttttt gatattccaa catctttttc ttcatttgat tgagatagtt aaaatcagcc
    31081 acgtttacat catttgaaat caaattttta gatccaatat ttaactctgg atgtgcttct
    31141 aaccaatcac tcataatgat ttctgtccca ttgtaaccac ctcggggacc aatccacaat
    31201 cctaggcttg aaccaaatcc atttacaaga tatttaatat ttctcaaacc atttgggaat
    31261 ttatgattga attcccaaac tgattgatag tttgtccaac catcatcaac aacataagca
    31321 tctaaatgaa ctccatgatt ttcaaatcca tctcgaatct cagaaaaact ttttaaaata
    31381 ccttcctctg taatatcggt catatggtca taccaggaat tatactgttt acggaaataa
    31441 ctaggttgag ctattccttc aacatattca aaaaatgcct cttgaatctc ttctttttta
    31501 taagaacatg ctcccccaat aatacaagac cacaaactct tttcttgatt tacaacagtt
    31561 cccaagtaat atcttgatac atagtgtcta ccatctacct tgttttcaga cattggaaat
    31621 tccattccta agaataaaga attcgcataa acaggttgtc ccaattctac ataataaccg
    31681 gaaaaattcg ccatttcctt aatacaatct tgtcttttcg gatagaaaat attgtcttct
    31741 gtttcaaact caaaactctc tacctctaca gatttaataa cctcagtaga tgattctaaa
    31801 actaattgct tcgaaagaac atcatccctc gattcaaaga ttaaacgtaa acgaatggaa
    31861 ggacaaacaa aagaaacctg aattcgcgta tctccctctt ccctaacgat tgctgaaaaa
    31921 tgatttgaag aaagtcttat accattctcc aatgtaatgg taaattcttc tttcgaaaca
    31981 tttttatcat tactcctgcc cgtttgttta cgatatcagt agtataaaat cgaccatctc
    32041 cccaaaagaa attacgtctt acatttttat tttcaatttt catataaact actctctcaa
    32101 ctcaattttg attacgctat caatcaagtc tggtaatgga taggtaaaat gtggaacttc
    32161 tccaaactgt gcaaaacaaa ttcctttgta ggcattggtc gtccagcttt ctgaaatttt
    32221 cacctcactt ccatcatgaa gaaagctcat tctttttacg ttttctttac taataccaag
    32281 aagagctaaa ggacctatag gttgttcaaa tacatgagca taaaccgtat ttccattacg
    32341 agtatagtat ccccaatctg gttttggtaa attttcatct ccactacatc cataaattgc
    32401 ctcaccattt cgagacatcc atcgatgaaa attatctaat attttcttac ttgaatcatt
    32461 aattcttccc aaagcatctg ggcctacatt aagaatcata tttccgtttt tactaacaca
    32521 ttccactaac tttcttatca aagtttgact agacttatat agataatctg taggattata
    32581 agcccaattg ttattcatag ttagacaaag ttcccaagga acaggttcac ctttaaagtt
    32641 tcgaatacct tcgtgaggaa caatttgctc tggactaaca aaatctccag cgtaagaggt
    32701 aatttcatct gtaacgatac ttccgaatcc ttcacctgat gtttctaatc tattatctac
    32761 gataacgttt ggctgataat gacgaaccat gtctattaat tttgaagctc cccatttttc
    32821 acccaccatg tcttcataag aataatcaaa ccataatatg tcaatctgac cataaccagt
    32881 tacaatttct ttaacttgat tgtgcaaata ctccaaataa cggtcaaagt taattttctc
    32941 atctcgatag gcttcatttc ctctcattgg atgatttaga tcagcatatt tagggaaatc
    33001 aggatggtgc cagtcaatca aactaaaata taagcctact tttaaacctt cagctcgaac
    33061 agcatctaca aattctttaa ctaaatctct acctgcaggt gtatttgttg ctttataatc
    33121 tgtaaatttt gaatcaaaca aacaaaaccc atcatgatgt ttagccgtta aaaccatata
    33181 cttcatccct gcagcttttg cttgtttagc ccattctcta gggttatatt ccttaggatc
    33241 aaaagctcga aaatatggtt cataatcttc aatagataat ttctgatgac tacgaatcca
    33301 ttcccctttt cctggaatag aatataaccc ccaatgaatg aacatcccaa atcttgcttc
    33361 tctaaaccac tgagttctac tattgatagt ttcaagtgta tgtttcatcc ttttactgct
    33421 cctcctccta aagcttcaat gaagtattta cttgtaaatg cgaatagaat gattggtggt
    33481 aatacgatta caacaatagc tgaaaataga ccattataat tagtattaaa acttgtagta
    33541 aattgaccta gtaatgctgg tactgttaat tcatttttat caatcaccaa catagatgcc
    33601 caataatatt cattccagtt attaataaag gcaagtactg ctgctgttaa aattcctggt
    33661 ctagcaattg gcaacatcac tttccaaaaa gtttgagcat atgtcgcacc atcaatctct
    33721 gctgcctcct ccaattcttt tggaataatt tcaaaatagt tctttataat aaagaaactc
    33781 atagcaattc cactacaaga gtagaccaga attagagcaa ctggggtatt ataaatcccc
    33841 aactcattta ctaatctata aactggaaaa gtcatagctg ttgctggaat aaatagagta
    33901 gaatacagca tagaagtcac caacttcttc cctctaaatt ccatcctagc aataacatat
    33961 gaagacatgg agatcataac aatgctaata ataactgata tagacactac tttaaagcta
    34021 ttccaaaagt aagtaaaaac atgaagtttt gtaaaaacat ttatataacc ttcaagagta
    34081 aagtcaatcg gtaaactaat acctggattt ttcataggat ctgcttttaa tgatgataaa
    34141 aaaatccacg caatagggaa aatagaaatt aaaatggtaa ggagcatata accatatata
    34201 agaactttgc cttttttact aataccattt atatgtgtat tcataatcat ttcccacctt
    34261 tcagtctttt tctttctctg aataaaatat taatacaaac gataatcaac attccaccta
    34321 agatttgtat aactccaatt gtatttgcac gagcatattg agttcgtgag ctagccactg
    34381 ctaattctcg aataacaaaa ctgatacttt ttgttcctgc agcaccattt gtcaaaaaga
    34441 atacttcgtt atagagcaaa aatcctgaag ttgctgccat aattgaaaca gttttaattg
    34501 tccccttaat catcggaatc gtaatatacc actctttcct ccaaccagta atattgtcta
    34561 aaatagcagc ttcttgaact tcttctggaa tagcaaaaat ttgcccaaga atcataatgg
    34621 ttgatgctcc tgcaaagaag atataagcgc cagtcatagc tactatattt aatcctggag
    34681 tcaacagtac tgaatcttta aacgatggat taaatagatg aataatttgg ttaacaacac
    34741 catagtttgg attatagatt tgaagaaaaa tcaagcccat agcagcacta gaaatgatac
    34801 ttggtacaat ataaagattc ctagatatct tccagccttt taatttctta gataatgtaa
    34861 ttgcaacaga tacagctaaa ggaacttgaa taataacacc aattacagcc caacgaacag
    34921 aattaattag agcttctgta aaaaatgggt attctttaaa aacataccta taattttcaa
    34981 ataatttatc aaatccaaga aactcagggg tgtttaaatt tgtataatcc catttagcaa
    35041 atgaagttaa aaagattgtt actacagaat aaaaataaaa tagaaagaaa caaatcaacg
    35101 ttggcaaaag aaataaaaag ataaatcgtc ttttttgatt cttcctattt tgtaggctca
    35161 taattttttg tgccataaac aaactccttt tttcaactat ataagtaaaa tcaaggtctt
    35221 atcaaaagaa agcacggata cgtgaccctg tcctctatga acacaattga actttctcat
    35281 caaatacggg aaggagaaag tactaggcaa aaaagactaa tcgctagtct cgctaaagac
    35341 tttattcggt ctggtatgtg tatctatctg gattccagta ctactgtcta cgaactctgt
    35401 ccctatcttt ctgaacttga taatttgatt atttttacaa atggtttaca tactgcacaa
    35461 accctatctg aaactgttaa agatagctcc aaaatcttta tcacatctgg cgaggtcaaa
    35521 catcaatcct gttccgtggt caactatgat aaggaaaatt ctttattaga tcattttaat
    35581 atcgatttag cattttgttc agcaagaggt attgatgacc aatatgttta tgaagcttct
    35641 ctcagccaag ctatttcaaa aaagaatatt attgacaaag cccatgaaac catcttactg
    35701 attgatagtt ctaaatttta caagactgga ttttttaaaa ttaatcccct ctccaaatac
    35761 acaaccttta tttctgacac cgtgccagac caaaaattat tagacgcagt cgaattattt
    35821 gatggagaat gggtttctga tattcaatga aaatcaaata ggaagctagt ctcagcttgc
    35881 tcacagtaca gatttgaaaa ctgatcaagt caagtccccc atggacacgg caagacgaag
    35941 ctgacatgat gtgaagagat tttcgaagag tattcgttct gtctgctgac tgatttacaa
    36001 atattcacca catgacatta ttttcttagc aattctaaaa acagaggctg gacaaaaact
    36061 caatttcagg agaaaatgga gtaaaccttc ccacaataaa acgcatagta tcaagttttt
    36121 gcacacctga tattatgcgt ttttctgatt ttaaagactt tgtcgcctag accctatatt
    36181 tcaagaatta agtgaccttg atgatctaaa tatattgtgg tatactattt ttgtcatcgg
    36241 ttaccgatta cgttcctatg ggtttgtgag aggaggtgaa actaatgagc cttatcatag
    36301 agctcgctct tactattata gcggatgtta tagctggaat tatcttgtat ttcgtctgca
    36361 gatggctaga tagtaaggag tagaccgact gactagccta taaacacccg ttaaatcgct
    36421 aagatacgtc aaaaaagccc ttaactacgg ccatagttag gggctttggt gttctaatga
    36481 accttatcaa ttaactacat tttagcatat aatctacaat agttcaagca ttaagtgagg
    36541 ttgatgatct aaatttagtg tgatataata cttttgtcat cggttaccga ttacgttcct
    36601 atgggttcgt gagaggaggt gaaactaatg agccttatac cagagcttgc tcttactatt
    36661 atagcagatg ttatagctgg aattatcttg tatttcgtct gcaaatggct agatggtaag
    36721 aagtagaccg aatgactagc ctataaacac ccgttaaatc gctaagatac gtcaaaaaag
    36781 cccttaacta tggcactagt taggggcttt ggtgttctaa cgaaccttat acactaacta
    36841 cattctagca tataagccca gatatttcaa gagttttatt tattttttca ggttccctta
    36901 gttctgaaag gtctataatg aagttagcca tctagtatca aaaaaccgac tagctcttat
    36961 gaactagtcg atttctcatc aatgcgccaa catttcttgg gcgatttctt ggccagatag
    37021 gttatctggg tagtaggttg gccagttgtc catttcttca aagagggctt cttggcttgt
    37081 gcctccaaag aagatatgga aatgttctgc cttaactggg gcaacattgt ggtcactaaa
    37141 ctgaacatac ttgaattgtc cagcgtcagc atctgtggct tcaaagagga aacgcacgcc
    37201 acgattgcct ttcttgtaag tcaaaatttt cttaccgaca tacttgtaag tgtatttctt
    37261 gctttgtcca ccttgaacaa attccatagt attatcagta atgttaatct tagtcacatc
    37321 tgtctgatag ccttttgtat agtaagcctt gtactcagcc tgggtcatct taccagttaa
    37381 cttagccttg tagtcaaaga cttggtcaaa cgtgccgtct tcaaggaaag gataaactga
    37441 ttgccagtta cctgcatagt cactcaaggt acggtccttg acagctgcat cctcgaagta
    37501 accattttgg actgtcttgg tatcctctgc cttttcaggt tcgattgctg ggccttcttg
    37561 gtctgttgtt tgtttcaaag ccttgaggtt tttctccatc acggaaatgt agttttctcc
    37621 agccttggtg tcctcttctg tcagactttc taaaggattg aggacatcag ttttgacacc
    37681 tgcttctttt gaaagtgtgt tagcaagggc ttgtgaggca ttttcttcaa aatagatata
    37741 ggcgatttta tttttcttga catactctgt caattctgcc aagcgagcag ctgatggctc
    37801 tgcatctgga gaaagtcctg agattgcgac ttgtttgagt ccatagtcca aggcaagata
    37861 gttaaaggct gcgtgttgag tcacaaagct cttttgtttt gcttgagaca agccttctgc
    37921 gtaagcctta tccaaggctt gcaatttttc gatataggca gctgcattct tctcaaaggt
    37981 ctctttttta tcaggataat ctgctgacaa gctgtcgcgg atgtgctcta ctagtttaat
    38041 ggcacgaact ggtgataacc aaacatgggg gtcaaactca tggtgatgac cttcttctcc
    38101 atggtcatga tctccctctt cttcctcgcc acctggcaag agcaacatat cgcctgtcgc
    38161 cttgatggtt ttcacttttt tcttatccaa ggtatctagc aatttaggta cccatgtttc
    38221 catgttttca ttttcataaa caaaggtatc tgcatcttgg attttggcaa ctgccttggc
    38281 agatggttcg tattcatgag gttctgtccc agcaccgatt aggagttcta cattagccgt
    38341 atctcctgcg acttgcttgg taaattcata gacagggtaa aaggttgtca cgatattgag
    38401 tttaccatct gcctgttttt gattggaaca agccactaaa aacaaggcac atagactggc
    38461 tagtaataag ctaatttttt tcacgttcgt ctcctatttg ataaaacgtc ttactaaact
    38521 gattagtata aagacagtta caaaaataat ggtaatactt gcacttgcag gtgtttctgc
    38581 atagtaggaa atgtaaagtc ctgctaccat tcccaaaaag ccaatcgcac tggcaagcag
    38641 cataaccgat ttaaagtttt tccccagacg cagggcaata ctagctggca agaccataat
    38701 ggtcgatacc agaagagctc ctgctgcagg aatcataagg gcaatagcca cccctgtcac
    38761 catgttaaaa agaatggaca tggtacgaac tggcaagcca tccacaaagg ccgtatcttc
    38821 gtcaaaagtt aagatataca taggacgaag aaagagaaag gtcaaaatca aaacaaccgc
    38881 cgcaatgaca aagagggaaa tgacctgttc ttcactgata gtcacgatcg aaccaaagag
    38941 atattggtcc aaactcattg aactcgagct tttacccttg ctcatgacaa tcagagaaac
    39001 agccagacct gttgacatga ggatagctgt cccgatttcc ataaagctct tgtaaaccgt
    39061 acggagatac tccagaaaga ccgccgcaat caagacaatg gcaatagtag aaacagttgg
    39121 agaaatcccc aaaaccagac caaaggctac acctgaaagt gagacgtggc taagggtatc
    39181 actcatcaaa ctctgacgac gcaagatgag gaaggttccc aataccggtg agaaaagact
    39241 catagcaata accgccaaaa aggcgcgctg tataaagtcg taagataata aactaagcat
    39301 ggcccacctc ctggccattc tcatgaacgt tgaaacaacg ccatggcgag tcttggttac
    39361 ggactagatg aatattgcga tccgcataat ccttaacttc ttcagggtca tgggtaatca
    39421 tcaaaacagc cttgccatga tgatgggcgc tgtggtgcat gagttcgtaa aattcatttt
    39481 tacttcctgc atccatcccc gttgttggct cgtctaggat aaacacatca gggtcagaag
    39541 caaacatacg cgcaatcacc gctcgctgct tttgtccccc agatagagac cccaagcgtt
    39601 tgtctcgatg ttcccacatg ccaactgagt ccagactggc cttgatatgc tcctcatcat
    39661 gagcattcaa acgacggaac cagccttttc tcggatagcg acccgacttg acaaattcat
    39721 agaccgtact tggaaaacca acattaaaac tggcaatttg ttgaggaaga taggctattc
    39781 tcaatttctt accttgcgta tttgtctttg aaatagccac ctttccaatg cgtggttgca
    39841 gaattccaag actagccttg atgagcgtcg tcttagccgc tccattttcc ccagtcaagg
    39901 taacaaattc cccactatca acactataat tgatatgttc aagaacaggc tccttatcat
    39961 aatagaagga caaatcctct accgtaatat atctcattat ttgatttctc ctactaaagc
    40021 agtcaaaaac cgctgaatca ctttttgttc atttggagta aactgagtcg ccacttgttc
    40081 ataggttaaa agtgtatgct catggtgatg gtggtgctcc tcagcgattg gacgagccaa
    40141 gtcagtcaac tgataaaaaa tcacacgcgc atctttagaa tctttagatg tttccaacat
    40201 cccttccttg accaaagact taatggcctt ggtaactgcc gcctgactga cattgagacg
    40261 acgggccaat tctgaatttg ttaaagattc ctctgacaag agcataagga tatgctcctg
    40321 agtattggtc agggccacct cgctagtgca atgacctatt aggatttcat gctgattttc
    40381 cgcctgcaaa atcacctcat tcaaaaaagc attgatatcc tttgctagct gtctcatatc
    40441 tgactccttt ccttttagac ttctcttttt taagagaaaa atactattct ttgacatttt
    40501 gtttaccagt taattatatc acaagcaaaa aaagagtcaa gaaaaaacgt gaaaactagt
    40561 ttcattcttg aactcttcta tattatatta tctattgaaa ttctttgaca tctccatcat
    40621 aagtcgccca atctttgctg aaaaagcgct cattcagatg gtaagtcgga gctggtgtgg
    40681 gattggatag gaaaggatca actgccttgt caaaagccaa ccaacccaac cagccaaggt
    40741 gaatggtgtc cttcataaag aaaggctccc cgccgtcctt agaaaaatct gctatattgg
    40801 taaaaccttg actttctaac tggtagcgaa tcttctgcac cgtttgttga tacatatcct
    40861 ctcgtagacc agcatagtcc atccattttt tattaacagg tggaatgata aaaatcgggt
    40921 ttaccttaga tttagaaaac tgtgttaaaa ccaactgcaa gtcattatac tctggcgact
    40981 tgagataggt aaagcttttc tgagaatcct ttaatttctt caaatccttc ttgatctgct
    41041 cattatagaa ataattttcc attcccatct cattattgga agtatttttt tcagcatctg
    41101 ctttgacaac atcttctatt gcttgataag aaaactggtc tggcaagatt tttaaatact
    41161 tagctacatg cttatcgtag ttaacatagc ctctaaccga aaactgacca aaaaaggagg
    41221 cttggcgttc attaaaacga gccaataatt caatcatttc attgtctgct gtcgacaatt
    41281 cttctttact tgccaacttc tgaaccaggt ccttcatagc tacgtttggg aactgttgca
    41341 gtaagcgagt cgctgcatat tgactagcct gatccccaga ttgatgtttc agaaaactag
    41401 tcaactggtc tccattaaaa tactgctgga aggctgctgg atcatagcca tttttactga
    41461 accactgagg tgagataaca tacacaactt gtttattctc cagctgtggt aacatctgtt
    41521 gcattccaaa atattggtta agcgatgcag ctcccccctg tcctaaaaga taaggacggt
    41581 aggaacgatt gtatttctca gctaataccg caggatgagc accgtcaaaa cgaagccatt
    41641 cactagagcc aaagaaggga acaaaacgca catttggatc agatagtgct ctgacttttt
    41701 gacttcgctc cttaaaacta tcgatagtag tagccactgc tgaacgcttt tcagctccta
    41761 gattatgatg catctcagta ggataaaaga aaatgagcag aaaaaccaac aaaccagcga
    41821 tcaagaccgg tccgaagatc atccataagc gtttaagcat tttgtagctc cacaatacca
    41881 gctatgattt tattagctgt attccagtcg tcacgaccaa actctgttac agggacacga
    41941 atgtcaaaac ggttctcaat ctccacaatc aactcaaccg ttcccatact atccaagaca
    42001 cctgcatcaa aaagatcttc atccatcatg tcagaaacat cttccataaa caactcatca
    42061 ataatttcaa taacttctga tttgatatcc atattttatt tccttttatt ttttaaacca
    42121 tagattattc aagaatccag aaaagattaa gaatgacaac atgacaacat ggaaagtgat
    42181 aaccatgcca agcaactgaa tccagcgatt ctcaggtagg gcagccttcc ctgctttttt
    42241 ccgttcctta ttgagcgttt ttttcttgcg aacccaggca tcattgatga ccaagcctag
    42301 tccatgaaag agtccatagg cgatatagta ccaggtcaca ccatgccaaa atcccataat
    42361 cagcatattt acaatgtagg ccatgcttga ggttacatta cgatttttaa agactttctt
    42421 tctggttaac accatcacca ttcgcataaa gacaaagtca cggaaccaga aggacagact
    42481 catatgccag cgattccaaa actcctttaa atcccttgat aaaaagggct tgttaaagtt
    42541 gatagggcta cggattccca tcaagtttga gatggccaaa gcaaacatag aataacctgc
    42601 aaagtcaaag aagagctcca gaccaaaagt atacataact gccaaggcat agagattaaa
    42661 gaagccacct gactgcaagg ctaaattctt cagaggaggt agtaaggtct ctcctaaaac
    42721 atgagctagg ataaacttat acaaaaagcc ccgcatgata tagcggacag attcatccag
    42781 catatccatc aactcatctc gctcaggaat ggcctgataa ttttcattaa atcgcttaaa
    42841 acgatcgatt ggaccactcg agaaagttgg catgaagaga aggaaacgga ggaattccca
    42901 gagggtaaaa tccttaatca ctccatctct cagctcgatg ataatcccaa ccgaacgaaa
    42961 tgtcaggtaa gaaattccca agaacccaag caaagactgc gttccattga tagctggttg
    43021 caccttgaca aagataatcg gaagtaggga cagaaaacta actaagtaga agacccactt
    43081 gccatccttg ctttttcgat aatgcttgta gaaaagcagg agcaatattt cccagcaaag
    43141 gtaaataccc aaggcagcta gttgattggt ctttccaccc accaacatgg tgacaataaa
    43201 gaagagactt accaacactt cataccaggc aaagcgtttc ttgaaaaaga gacctataaa
    43261 gatgggcaag gttgcagcaa tcacataaac aaaatactga ggattgccat atggctctaa
    43321 atgaggaagc tgttgaaaaa actccatcat ctcttattca cctcgttaat caatcctttg
    43381 atgtcaatct ttccatttgg agttagtggc aaactgtctc ggtaaaggaa tttagatggc
    43441 atcatgtagg acatcatgat gtctgtcagg tcttccttga tggccttggt aatatcgata
    43501 tctcgctcaa actgctcacg aacaccgtct tttaagatga cataagccaa tagattttgt
    43561 accttgtggt ccttgttata gcgcggtact gcgacagcag attcgataaa gcgagacttg
    43621 ttgaggtttt gagagacatc ttctaactca atgcggtaac cgttaaactt aatctggaag
    43681 tccatgcgtc cgccgtagag aagcaagccc tcatctgtca tggttcccac atcgcctgtg
    43741 tgataggctg gcagaccttc aaactcaaag aaggcttctg ctgttttttc aggattgttc
    43801 atataacctt ttgaaacagc tggcccagaa acaatgattt ctccctgttc gccatttggc
    43861 agtttatttc cttcctcgtc aatgataaag gttggagaat cagccttggt atagccgatt
    43921 ggtaggcgtt tgagagtcgc taacatctcg tctgtaacag caactgctga cagagctact
    43981 gtcgcttctg ttgggccgta agcattgatg atacgggcat ttgggaaacg ctcgcgcagt
    44041 ttttgagctg ttttgaccgt caattcttca ccatcaaagt agaaatgcgt gattccaggc
    44101 attttctcac tgttgaagta ttcagacaac atggccatat ctgcaaagga tggtgttgat
    44161 gtccagatag cgattggcaa tgaaaagata gccgcaaaga gttgcttaaa gtcctgagtg
    44221 atgactgaag gaagagtgaa aagcgtacca ccaagtgcca aggtcggtgc ccaatacatg
    44281 acagacaagt caaaagaata aggtggctgt gccagcattt gcggacgact cggtgtcgca
    44341 aattccttat ccgtaatcat ccagtttgta aagctgagga gattatcatg tgaaatctgc
    44401 actcccttag gcttaccagt cgtaccagaa gtaaagataa tgtagtaatt atcatctccc
    44461 ttgactggat gcgtgatttc atagttgttc ccttgggcaa aggcttcttg aacctgagct
    44521 agatttatca ttggtgtaga aacctgctcc aagggaaagg ctgaaatggc aataatcaag
    44581 cttggctctg ctacttctaa aatagctgaa actcgctcca aggccgaatg gctatcaatt
    44641 ggaatgtagg catgacctga cttagtcagc gctacaaagg ttgccaacat ttcatattct
    44701 tggccaccaa aaacaaccac aggagacttc tcaggcaagc ctagttggtc aatgactgca
    44761 gctaaactat ccgaatcagc ctttaaatcg ccataagtgt gttcctgccc caaaacatta
    44821 tagacaggat agctaggctg tgtctgagca aaatgctcaa tggtttcaat catatctgct
    44881 attggtttat ttgacacaat agggattctc cttcaagtta aaattcatta tagataaagc
    44941 ttccttgacc ctgaccaaga tagctaaaga agtaaagcag ccctagaaag ataagaaaat
    45001 acaaggctgt ccgaccaaga aagaggtaca attcttttct ctgtttcatc aagaaaaacc
    45061 attcatttct gtaatttttc gctaaaataa gagtgattct tactagctta tttttctacc
    45121 attgtaccac tttatatagt atcttttcaa ttgtttaccg tatgtttcca atagatttca
    45181 gcttatttta aggattatgc ggtttttcta tatctatttc aaaagaaaaa agcctgagat
    45241 tttcatctca agctctagca ataatagtta ttttctaaac taaaaaagtg agaatacaag
    45301 cacggccaag gctgctccga taacagggcc tacaacagga atccaagcgt aagaccagtc
    45361 tccgtctccc ttgtttggaa ttggcaagat gctgtgcatg atacgaggtc caaggtcacg
    45421 agctgggttc aaggcataac ctgttgtccc acctagtgat agaccgatac cgacaatcaa
    45481 agttcccact gcaaaggttc cgatacctgc ctgaaagtcg taaagaccca aagcaaagat
    45541 tgtcaacacc aaaacaaaag ttccaaggat ttcgctaatc aagtttgata cagtatcctt
    45601 gatggctggt ccagtactga aggttgccag gatattgcct gcattttctt ctgcctcata
    45661 gtgaggtttg aattgcaacc aaaccaaaat ctgacccagc atggcccctg cgaactgggc
    45721 taagatataa ggcaaaacgg aagcccaagg caaaccacct tttaaggcca caccgatggt
    45781 cacagctggg tttaaataag ctggactgag cttgccagat acaaagactg caaccgcaac
    45841 tgcaatcccc caacccatag taatcacaat ccaacctgag ctattgctct tggttttagg
    45901 aagaaccaca cctgcaacaa caccatttcc tagaagaatc aggattaaag tccctagaaa
    45961 ttctccaaat aattcattca tcatctttct gtctccatta aaaagaaggg acgggcgaca
    46021 aggaatgctg ccctccacct cttttatttt ttcttaattt tttaattctg ctaaatcgtt
    46081 gttagcgaga gctgcttcga catcagcacg gtaagttgct ttttcttctt ctgtccagtc
    46141 atagaatcgt cccatttcat ccaaaattgg ctcaacgata ctatccaagc tatcacgcat
    46201 aaagagcatg tgattggtac gacgaagaag gaagtcaact gggctaagag tcaactcatt
    46261 gcgcattgca tagtgaaggg acaaggtgtc tgccaagcta agacctggcg cttgttccaa
    46321 gctgtgagca agtgcaaaga ccttcggtgc atttgaaccg taaagatttg ctaggtaatg
    46381 agcttccttg ctatccaaac cacgtgaaac tccaagttgc gcaaaggctt cgatttctga
    46441 atccacattt gctgggttca attctccacc tgaaacaggg taagttttag aattgatcaa
    46501 tttaaagcta cggtcaaatt ctgctttgag gatgtcaacc acgcgctcca tagctccttc
    46561 agccatctta cggtagtctg tgattttacc accagcaaga gtcaagagac cattgtcatc
    46621 acggtccaag ctagacccac gagaaactgc agatggatcc aaatgtttct cagatgtgct
    46681 actttcaagc ttgctgacag cagactcaac atcttcacgt gttttttctt tggagagata
    46741 agattcaaca gtcgcaatca agttgtcaaa gctttcatca ctgatggtac cgttatttcc
    46801 accattatag tcagaggcac tgttccctgc aatcaatgga cgaagacctg cccagctgct
    46861 ttcgatatca tcaatggtga tgttggattc tgggaagcgg ttgttgacaa tgccaagtag
    46921 ataatctaca tcttcttgag ttacttttgg atgctccaaa tcacctgtgt agtctgtatc
    46981 agttgtacca aagtaagtct tgttttcacg tgggagaaca aagaccatac gaccgtcacc
    47041 caaacctgtg tcgaagtaaa ctggctgtga aaccttgatt ttacttgaat ccactaccaa
    47101 gtgaactccc ttagttgggc gcatttgtga gaattgcgtt cccttattag acaaattacg
    47161 tactttatca ctccaaggac ctgttgtatt aataaccaga cgggccttga tttcaaatac
    47221 ttggtctgtc aagagatcac gagctacaac acctgtaatc ttgccacttt cgtcaaagag
    47281 gaagccttct gccttcacgt ggttggcaat gagggcaccg tcttggttgg cacgtttgat
    47341 gttttcaatc acgagacgcg catcgttgtt acggaagtca agatacactc cacctcctac
    47401 caagccttcc ttcttcaagt ttggctggcg ttccaagact tctttcttgc tcaaaacctt
    47461 gttcgcagtt ggtgtgttgc tcacacctgc taaaaggtcg tacaagtcca tggctacttt
    47521 aagacggaag aggctaaagg ttgctccatc ttcatcgtaa actggtaaga gcattggatc
    47581 tggttttgga atgtgtggag cgatttgttg aaccactgca cgttcagaaa ccgtatctga
    47641 gaccacttct acgtcgaatt gtttgaggta gcgaagacct ccgtgaacca attttgttga
    47701 acgactagat gttccttctg caaagtcttg catttcaatc aaaccagtct caagaccgct
    47761 agctgccgcc tgcaaggcta caccagctcc tgtgattcct ccaccgataa tcaagaggtc
    47821 cagggtgcgt tcctgcattt ttttaattga caattcacgt gttttctttg aaaattccat
    47881 atttacacac tttctaaata aatcgcttta ttctgccagt attagtcgtc tacttccgca
    47941 aagacttgag ttgctttcac agccttcttc cagcccttgt agagttgttc cttgcgagat
    48001 tcattcatag atggctcaaa gagttctcct gtctcgttca agagtttcaa ctcgtccaag
    48061 tctttccagt accctactga taaacctgct aggaaggccg ctcctagagc tgttgtttcc
    48121 aagtttttag cacgtgcaat atcaatgcct aaaatatccg cctggaactg catgaggaag
    48181 ttgttcatgg ctgcaccacc atccaccttc aatacttgaa tggcagtctg agtatccact
    48241 tgcatggtgt cgatgatgtc acgcacttga taagcaatag attgcaaagt cgccttgata
    48301 aagtcttctt tgcttgttcc acgagtcaaa ccaaagacgg aaccacgagc attttggttc
    48361 cagtatggag cgcctagacc tgtaaaggct ggaacgacat aaacttcatc gttgttgtga
    48421 gaatcacgag cgtatttttc agattctggt gaattttcaa ccatgcgaag accgtcacga
    48481 agccactgaa tagcacttcc tgcgatgaag atagaacctt ccaaggcata ataaacctta
    48541 ccgttgattc cgtaaccaat ggttgtcaag aggttgtttt cagacaactg catctcttcc
    48601 ccagtattca tgatgatgaa agagcctgtt ccataagtat tcttaaccat acctggctca
    48661 aaagccaact gtccaaagag ggctgcttgt tggtccccag ccatacctga gattggcacc
    48721 tctccaccgt agaaatggaa tggagctgtc ttgccgtaga tttcggagtt agaacgaact
    48781 tctggaagta tagccttcgg aatgttaagg atttccaaaa tctcatcatc ccatttgagt
    48841 tctttaatgt tataaagcat ggtacgagct gcatttgagt agtcagtcac gtgagccgca
    48901 ccgtcagtca atttccaaac caaccaagta tcgatagtac caaagagcaa ttcccctttt
    48961 tctgctcgct cttgagcgcc ttctacatga tccaaaatcc aacgaacctt ggtagcagag
    49021 aagtaagcat caataatcaa accagtcttt tcatggaatt tttccacata accttggctt
    49081 tttagttgct cagccaaagg tgctgtctgg cgtgactgcc aaacgatagc attgtagata
    49141 ggaagtcctg ttttcttatc ccagacaacc gttgtttcac gttggttggt aatcccgatt
    49201 gcctcgattt gatttggctt gacgccactt tcgatgaaag cacccgcaat aactgactga
    49261 acagagttcc aaatttcatt ggcattgtgc tcaacccaac ctgcctgagg gaaaatctgg
    49321 gtaaactctt tttgactcga gctaaccttt tccccttttt tgttgaaaat gatggcacga
    49381 gaacttgtag ttccctggtc aatggccatg atgtattttt cttgtgacat gtactgtcct
    49441 cctgataaag atcttgaggt gtttcctctt tacacttact agtatacaaa ataaagcgct
    49501 ttcttgttta tcaacttttt ttaattttta aaaaaatgtg aggagattgt gtgaatttca
    49561 caaaaaagac ctggattaac caagcctttt aagtgaataa taactgacga atccctgcca
    49621 aatcttccat atccaagtca ttttttaaat aatagactgg ggtctgttcc ttcttatgaa
    49681 tcgggttatt ggtaaccagc aaatcataat gccgactagg gtcataagct tcaatggtaa
    49741 taaaacgatt gtattccaaa taccgtttca aaatggctgc catccttgaa aagacaagaa
    49801 aaccagatgt caaatccaga ccaatccgca tatgctggcc accgttttca gccatatatt
    49861 cgattaactg gagccattcc cagagaatct tcttatctaa atctgtcccc tgttgaaaag
    49921 caggtagagc atgaaaaatc tcctctgctg tctctttaaa atcatgttcc atcagtaaat
    49981 atggatgacg attctctaac tggtacttgt agcgatcctg taaaatatag cccttataga
    50041 gatagacttg agcacaaagc tgactgagtt cataggtgac atggtcctct gtataatccc
    50101 ccaatagttc ctccttcttc atttcttgaa tcaattgcgt cagtaaatct gccaactgcc
    50161 ctccaaaacc aagaatatat tccatagtat gaagaggaag aatgcgatga gataggagaa
    50221 aagagaagaa tatcatcatc tcaccatcct caactcctag tggaatatgt tgcccagcaa
    50281 aaaaggacgg aacctttctc agcaaacgaa gatagaagat attgtcaaaa taccctcgca
    50341 ttttctcttc tatgacttga aactgacaag cattgacccg aagacgttgt tgactgatgt
    50401 gagctcagag aaccaagtcc aatttctgcc ccacagacaa acttgcaccg cagatttcct
    50461 ctaaattggc aatctcctgt tttctctctg gtttctgcat gtgaccttcc cattcctgac
    50521 tcgaccagac ctttcggaaa agacagaaat agaaatagcg aatctgatgc tctggacctc
    50581 gccaacgtcc attttggatg gataaatcaa attctgacaa aatctgattt aaaccagcca
    50641 agtgacgacc aagcgtagcc tcgctaatca ccaattcttg agccagctga tgggctaaaa
    50701 actgttggtg gtagagaaga taaaccaaaa tctggtattt aacagcactc tccaaaaaca
    50761 agctccgaat atctctcccc ttggtagctg caccgataga cagacgcaga ttttcatctt
    50821 ctgagtgaat agccagctct aagccactat ccaaagcctt gtcattgagc agggtgacat
    50881 atttggttag ggttgctttt gaaaatcctg tttcttccat tacagccttg acggtcgtct
    50941 gagactcttg taatagaaag gaaaggattg aaaattgacc acactcggct ttctccatca
    51001 aatctcctaa atacatttgt tacccctttc attttctacc ttaagcatag cataaatctt
    51061 acaaatgcta aaataatctg tttctctttt tattttcatg ctgatttcct ggtccattat
    51121 cctgaaaatc agtaaacaca cggctccccc tttgggcatt tttatgctaa aatagtagct
    51181 atggataaaa ttattaaaac tatatcagaa agcggagcct ttcgtgcttt tgtccttgat
    51241 agcactgaaa ccgtccgcac tgctcaagaa aaacatcaaa cccaagctag ctcaactgta
    51301 gcgcttggtc gaactcttat cgccagccag attctcgcag ccaatgaaaa aggaaatacc
    51361 aaacttacag ttaaggtgtt gggatctagc tctctaggtg ctattatcac cgtcgctgat
    51421 accaagggga acgtcaaagg ctacgttcaa aatcctggtg ttgacatcaa aaagactgcg
    51481 actggtgaag tcctagtcgg accttttgtt ggaaatggtc aattcctcgt tatcacagac
    51541 tacggtactg gaaatcctta caactctata actcccctca tctctggaga aatcggtgaa
    51601 gaccttgcct tttaccttac tgaaagccaa caaacgcctt cagcggtcgg cctcaatgtc
    51661 cttttggacg aggaagacaa ggtcaagatt gcaggtggtt tcctagttca agtcttgcca
    51721 ggagccaaga aagaagagat tgctcgcttt gaaaaacgca tccaagaaat gccagctatc
    51781 tctactcttc tcgaaagcga cgaccatatc gaagccctcc tcaaggctat ctacggggac
    51841 gaagcctaca agcgtctttc tgaagaagaa atccgtttcc aatgtgactg tagccatgaa
    51901 cgctttatga acgctcttgc cagccttcca agctcagact tacaggaaat gaaagaggaa
    51961 gaccacgggg tagaaatcac ttgtcaattc tgccaaacta cttacaactt tgatgaaaag
    52021 gacctggagg aactcattcg tgacaaatct taatacacct tttatgattg gcaatgttga
    52081 gattcccaat cgtaccgttt tagcgcctat ggctggcgtg accaactcag cctttcgtac
    52141 catcgcaaaa gagctcggag ctggactcgt tgtaatggaa atggtctctg acaagggaat
    52201 ccaatacaac aacgaaaaaa ccctgcacat gcttcatatc gatgagggcg aaaaccctgt
    52261 ctctatccaa ctttttggta gcgatgaaga cagcctagca cgcgcagcag aattcatcca
    52321 agaaaacacc aagaccgata tcgtcgatat caacatgggc tgccctgtca acaaaatcgt
    52381 gaagaacgaa gctggtgcta tgtggctcaa ggatcctgac aagatctact ctatcatcaa
    52441 caaggtccag tctgtccttg atatcccact tactgtcaaa atgcgtaccg gctgggcgga
    52501 cccatctctt gcagtagaaa atgctctcgc tgctgaagct gcaggtgttt ctgccctcgc
    52561 catgcatggc cgtacccgtg aacaaatgta tactggccac gcagaccttg agacccttta
    52621 caaggttgcc caagctctaa ccaagattcc attcatcgcc aacggtgata tccgtactgt
    52681 ccaagaagcc aagcaacgca tcgaagaagt tggtgctgac gcagtcatga ttggccgagc
    52741 tgccatggga aatccttacc tcttcaacca aatcaaccat tactttgaaa caggagaaat
    52801 cctacctgat ttgacctttg aagacaagat gaagatcgcc tacgaacact tgaaacgatt
    52861 gattgacctc aaaggagaaa acgtcgcagt tcgtgaattc cgcggcctcg ctcctcacta
    52921 tctccgtgga acatctggcg ctgccaaact ccgtggagcc atttcgcaag ctagcaccct
    52981 ggcagagatt gaagccctct tgcaattgga gaaggcttaa tagtttaaaa cccgtaactc
    53041 tcttaaagag cctcttgaat gccgccattc tttcctcatc aaaaaaactc cgtagtctct
    53101 agcgctataa atccagctag agattacaga gttatttttt aatctaaact tcctacaagg
    53161 gtatattatc tactgaaagg atatggtatt tgtagggaat actttaaaga gttcttacag
    53221 gaagtcagta ttaactagtt atattaggtt tagtttaccc attcaccatt ggcattgact
    53281 ctatagctat ctacagttgt gttgactgca agggcacctg agccattgac atagtaccat
    53341 ttatctgata ctttgaacca ttggcttgct ttcatagcac ctgatgcttc aagatagtac
    53401 caggtatctc catctttcac ccaatctgtt gccattgaac cgttagcgtt taggtagtac
    53461 catgaaccat tgttttggag ccatcctgtc accattgaac cattagcgtt taggtagtac
    53521 catgagccat tgttttggag ccatcctgtc gccatatcac cattatcgtt tagatagtac
    53581 catgaaccat tgttttggag ccatcctgtc gccatagcgc cattagcgtt gaggtagtac
    53641 catgaaccat tgttttggag ccatcctgtc gccattgaac cattagcgtt taggtagtac
    53701 catgagccat tgttttggag ccatcctgtt gccattgaac cattagcgtt tagatagtac
    53761 catgaaccat tgttttggag ccatcctgtc gccatagcgc cattgctgtt gaggtagtac
    53821 catgagccat tgttttggag ccatcctgtc gccattgaac catcagtatt gtagaagtac
    53881 cacataccgt tttcttgttt ccagcctgtt tttggagtag atggttgtgc tggtttttca
    53941 gtttttggcg gttgctgttg agtcaagcga ttatattctt cttctgatct acgagcatag
    54001 tcttcttcag cttgttgatc agctggtttt tctgcttttg gttgttcagc tggattctct
    54061 ggttttggag ctggagctgg tttttctggt tgaggagccg gcgctggttg tggttgttca
    54121 gctggttttt ctttaacttt atcttcttct gctgcttttc gtttagcttc ttctgctttt
    54181 ttacgatctg tcttgatttt ttctaacctt gtagcctcag cttttttact ctcaacttcc
    54241 gcttttgctt gcttaacttt ttcctcgttt cgagatccct tagcttcctc ttttactagt
    54301 tcaagctccg cttttttaac ttccacatcg gactcagcaa tttcaagttc aagcgttttg
    54361 taagtaatgg ttgggtagtt acggtgatct tcttcttttt gatccttggc ttttttctta
    54421 gcttcttcaa ccttcttctg agcttctgct accttttttt ctggtttcag ggatgggttt
    54481 ggaagagttt cttcacctac gctagaatct gaagacttcg catcattttc ttttttatca
    54541 ggtgttgctt gctctccagg aactcctcgt tttgcccgcc cctttggttt accttgctct
    54601 ttagcatctg ctcttcgttt agcttcttct tctgcttttt tacgttctgt cttgatttct
    54661 tctaaccttg tagcctcagc tttttcactc ttaactttct cttctacttg cttaattgtg
    54721 ccctcgtctc gatgttcctt agcttcctct ttcaatagtt caagctccgc ttctttaact
    54781 ttcacatcgg actcagcaat ttcaagttcg attgttttgt aagtattggt tgggtagtta
    54841 cggaaatctt cttctttttg atcctcggct tttttcttag cttcttcaac cttcttctga
    54901 gcttctgcta cttttttagt aagttctggt tcttttttaa actgctcaaa agctgcgtct
    54961 aactctgctt tagcttttga cggcaactca gctttcgact tctcttctaa taaaacatta
    55021 acttctaatt catacaaata cttcttttta atttcgctca actttgtgat taagccgaca
    55081 ttttgggtat gtcgatcttt ttccaaactt tttctgacct tctccaatat actttgataa
    55141 tgcgacttga cttcatcagc atacttcttc gatgtatctt gcccactaga tgtaaccgtg
    55201 gaggtattcc taccaccaac cccttctgca tggactactc ctcctaagaa caagctggca
    55261 actgctacac tagctactcc aatactaaat ttacgaattg aataatgtac ttttctttcg
    55321 ctttttgatg caaacatgtt tatttccttc tatatttttt ctttaacctt actatatcac
    55381 ttcaatatga actgtatata aatcgaattt tgtatttatc tctttatgct tccatttggg
    55441 attataactt catgtaatag cttttcctct tcagctattc gtcgatacaa aataactgca
    55501 taaactggaa aaactaaaac aaaagtcata taggcatgac tcaacaaggt caagccaatc
    55561 aactcaggta aaatatttaa aaagtaatta gggtgtttta ctgtcctaaa caagatatga
    55621 tctacatatt tgtgattatt gacaagcata agcttcactg tccaaatatc tcccaacaag
    55681 tgaatcacca acatcaacat cagcatagaa aaaataagca agactaaacc aaccatgccc
    55741 atgccatcaa aaattgtctt gtgcaccatt gcctcaacca agcaagagag ataaaaaaca
    55801 atatgagcca tagttaatcg ttttgtattc tcaactccaa attctttccc gccattgcta
    55861 aggattcgtt tctcattctc tatcgaacgc tttaaaaaaa tcaatcgaat aaggaatgtt
    55921 actaaaataa tcgctaatac catattagta tcctttcttt tatctacaca aagaataaca
    55981 cacttatgtt aaccctatat gaactttaat aaaaaactaa tctgtctaca agctaatctt
    56041 aaattccata ccgtgttcat aagggagaaa actataatcc atttgatagc tttctaaaat
    56101 attattcaca atgtaaagac ccaaaccgga actttcatcc ttatctgtca cgatttgaga
    56161 atgatagaat atatcaaata aatgttctag ttcttggtca cttagaggcg cacatgtatt
    56221 tttgatagag agatagccat cttgctcgga tatgattacg cgcccatttt tatctgaata
    56281 tttaattgca ttactaatca ggtttgtcaa aaccttatcc aatgccctaa gactcatgac
    56341 gaccctggta gcatctgtca attgattttc aattgtaaca cctattgaat gagctaattc
    56401 ttgataacgt gataaaatat ctactaaaac tggcttaaca gtcaaggtct cacgacactc
    56461 tgtccactct tggaatttag aagactccag tacttcttcc aataagtggc tcatctggtc
    56521 aatcttattt atactctttg caatatattt tggatgatct ttgtaatctc caatattatg
    56581 ctgcatattc tctaggataa ttctaagact ggctaaaggg gttttcaact catgtgatgc
    56641 tccgcggaca aaggaaacct tttgattttg caattttaca atttgctcat tacgactttc
    56701 caactcatga ataaccttca acaagtgctc atacatacca ttaatctgtt ttccaacttc
    56761 accaacttca ccaacttcat ctttcctact ttcatcaaaa cgaatattgt catccaaatc
    56821 ttgcatttta ctagtcactt ctgaaatgta aaaaagagga ttgagcaagc gtttagtata
    56881 aaaataagaa aaaacaaagg aaaaagcaat tgtaaccaaa aatgtatatg ggagatacaa
    56941 aagcaaaata ttctttgctt ctttgtagac atccaccccg tgaacaaatt gcactgttac
    57001 ctgtttacca tctgctgtac taacagacat atctaacatc acgatataat ttgatagctt
    57061 tccatcttta atatccaagt catgcacaag agggagtcgc ttatctacaa tatctctttt
    57121 aaggtgagca gatatggtca aggactttga ataagactgg agtaagcttg gaatttcatc
    57181 agatgtctta gtctttaaat actccgtaaa cactcttgcg ctctcattaa acttttcccc
    57241 ctccagttga atataataaa aaggaaaggt caaataaata gctatatgaa tgactagacc
    57301 aacaccacct agaattgcaa aacttcttaa aaaagacttg gttaataatt taggattttt
    57361 tatcataagc taatcttata cccaacattt ttcacagtca cgatacaatc taaagctaat
    57421 tttttgcgaa gagtacgaat atagacatca acgaccctat cacaaggtaa atcagctaca
    57481 tcttttgaaa tttcttccaa tatctgctct ctacttaaaa cttgattttt atgctgaatc
    57541 aaacacttta gtaccagtaa ttcctttggt ttgagatcaa tttcttcatt tttataatgt
    57601 gctttgtaag aggtaaaatc cactgttaca tcctgatatc gccaaatatc ctctatgacg
    57661 tagtaacgtc tgataagcgc cttaatacgc ttgacaagca gtaccaaaga aaaaggtttt
    57721 gtcacatgat catcagcata gagatcaaat acctgtgact gagtagtttc atctcccaga
    57781 gcactcaaga cgatgacagg aatatcgtgc ttttgattga tttcttttaa cacttcaaaa
    57841 ccactcttcc taggcatcat taaatccagt accatgagat ggatagggag atcttgaaat
    57901 ttttccaaga cctcttgtcc atccttagcc ataatgacat gataaccctc ttctgtcaga
    57961 aatgctgcaa ttccttctct aatcatttcc tcgtcatctg caactaaaat gttcatctct
    58021 ctccctttct actaccagtc tatcatctat gataatggaa tggatttcat ttatccgcta
    58081 ctttttgtca acaacaacgt caatacaaga aaatcattca tcttgcagct tatactcttc
    58141 gaaaatctct tcaaaccacg tcagctctat ctacaacctc aaagcaacct gcggctagct
    58201 gcctagtttg ctctttgatt ttcattgagt ttcactccac tgtgacttat ggtcagatgc
    58261 tgatactttt attcttttat gcaatatcaa attttaactg gcctgctttg acaccaatct
    58321 taagtgtgct gcctgccact aaatctccct taagaagaag ttctgccaac ttgtcctcca
    58381 cttctgtttg cagggttctg cgaagtgggc gagctcccat ctctgggtca tatccttgat
    58441 ttgctaacaa tttcagagct gaagcttgta atttcaagtc aatgcctttt tcagccaaac
    58501 ttgccactaa aggcttgacc ataatcttca ccacttcctg catatggtca ctagataggc
    58561 tatggaagac caccttctca tcaatacggt tgatgaattc cggtctataa gcttttttca
    58621 gttcttcaaa catgcgtttt tccatatttt cctggtcaaa acgaatatcc ttagccccaa
    58681 aaccaacagt cttatcatca cgaagggcag tcgcacctag gttcgatgtc ataatgataa
    58741 tggtatttga aaaatcgacc ttgcgtccct tgctatctgt caagacaccg tcatccagaa
    58801 cctgcaagag aacattaaag atatctgggt gagccttctc tacctcatca aagaggagaa
    58861 cggaataggg tttattgcga accttctctg tcaactcccc accttcttcg taacccacat
    58921 agcctggagg agctccattt agacggctgg ctgcgaattt ctccatatac tcactcatat
    58981 caaagcggat aagggctgat tcgtcatcaa agagaacttc tgccaaagcc ttggccaact
    59041 cggtcttacc gacacctgtg ggtcctagga acataaagga accgatcgga cgcttgtgac
    59101 tgcgaattcc tgactgatta cggcgaatgg cacgactaat acttgaaaca gcttgatctt
    59161 gaccgatgac acgtttatgg agttctgctt caagatttaa atacttctta gcatccgttt
    59221 gagtcagttt ttgaactggg attcctgaca agcgactcaa ggtggtcaaa atatcagact
    59281 ctgtcaccaa gtctttgtag acaggtactt cctcttcttt tgcgattagc tgggctgcct
    59341 gtttccactt gccatccatc agggccttgt cagctggact caaatctgaa tcgtctgctt
    59401 ttacatgctt tgccttattt tgcactgttg ctgctgcttc gtccaagagg tcgatagcag
    59461 agtctggcaa gtgacgactg gttaaataac gatgagccat cttaaccgct gtttcaaccg
    59521 cttcatctgt gatttgtaca cggtgatgtt tctcataagt cgccttcaaa ccttgtaaaa
    59581 tagtcatact atctgccaca cttggttctt caatcgtcac tttagcgaaa cgacgagaaa
    59641 gagccgcatc tttttcgata tgtttttgat attcttcctg agtggtggca ccaaccgttc
    59701 tcaaagttcc acgcgccaag gctggtttca agatattggc cgcatccaga gtcgaatcaa
    59761 tcccgctacc agaacccatg atggtgtgga gttcatcgat aaagaggatg acttggccat
    59821 cttcttcaat atccttgatg atattattca tgcgttcttc aaagtcacca cggaagcgtg
    59881 tccctgcaac gacattcatc aaatcaagtt ctaacacgcg catcttagcc atttccgcag
    59941 gcacgtcacc actagcaata cgctgggcaa gaccaagggc cagagctgtt ttcccgacac
    60001 cagcatcccc aaccaagaca gggttgttct tagtcttacg gctcaaaatt tgaatcatac
    60061 gtgagatttc cttgtcccga ccgatgactg gttctaactt gccagaacgc gcttgctctg
    60121 tcaaatcatg cgtatagtcc tcgagaccac cactaggagt ctgcggcatg cccatcatat
    60181 tggccataga attttgcttg tcagctactg tacgatggcg ttggcgtaaa gccttgagat
    60241 cttcacgagt ccagcctgcc cgttcttcta aatttcgacg aagagcagca atcttgacct
    60301 gatctttctt gtcttcataa gaaaaaccag ccctctccaa gatacgagtc gccaaggcat
    60361 tgccatcatg caaaatcgca tagaggacgt gctctgtccc tagcacctta gcatggacca
    60421 ctgacgctac atactctgct tcgtcaaaaa gaacctgcaa acgacgggag aacggcaatt
    60481 ccgtaaaggt ttcatcctgg ctatagtccg tttcagtcag ttccaaagcc acctcttcta
    60541 aacggtccat ctcatacgga taatcattta aagttgcccc tgctacacta taactgtgat
    60601 tagacatggc aatcaacaag tgccacgact ctagataacg agctccaaaa tgtccagcaa
    60661 ccatgtaggc actttcgata cattcattca atgcttttga atagttcatc ttacttccct
    60721 tttctatcta cctcttgtat gacctgacgt agcatgtttg ctcgaacaac tggagcttct
    60781 tctcctaaaa cgcgatccaa agctactgat tctagcaaat tcatctcctg cttggtcatc
    60841 aattcctgct caaccaaaag ctggagaata tcctcataaa tttcttgact gactcgctca
    60901 ccaatcgagt aaagcagctc ccggagcatt tcatgatgac tagaaaactc aatccgtcct
    60961 atacgaatgt agcctccgcc accacgctta ctttcaacca agtagcctct actttccgta
    61021 aagcgtgtct tgatcacgta gttaatctga ctaggaacaa cctgaaaggt atctgccaac
    61081 tgactccgtt gcaactccac gataccagat tgatctaaaa tcgccttgat gtaggcctca
    61141 atatgatccg atgtattttt aaatctcata acaaacccac ctctctcttt aaaccttgac
    61201 cttgtttgac tattataccg aaattttctc atttttaaaa gaaaaagggc gctggtaaag
    61261 gataatcttc accaactccc tatttttcta cttatctaag cctaattctg ccaagatttg
    61321 acgtttgtag gcaatctttt ggacttcctt gtcctcatct tcagaccaat ctagtttaat
    61381 ttctgaaaca atctgcccag ggcgattttt caagatatag atgcggtcgc tgagattgag
    61441 ggcctcctca atactatgcg tgatgatcag ggttgttagc tgcaactgct tgtgaatctc
    61501 aagataccaa gcgtggagtt ccatctttgt catctcatcc aaggcgctaa aggcctcatc
    61561 taagagaaag agcttgtgcc caaaaaggta ggtccggagt aaggctacac gctggcgcat
    61621 cccaccgcta agttcatgag gatacttgtc tcttacagct gtcagctgga aggtcgcaag
    61681 aattttatcc gctcgggaaa tagcttctgc cttatccacc ttttgaatca agaggggcag
    61741 aatgatattt ccaagcaccg tcttgtgctc caagagcaga tccttttgca acatataact
    61801 cacgcgcccc ttgggatttt cttcaccatc aaggacaatt ctccctgact gaacttctaa
    61861 aatcccagcg attagattaa agagggtggt ctttccaaca ccacttgggc ctaggatgga
    61921 aaccacttcg cctgaagtca cctgtaggtt gatatcctct aaaatcctct cctgaccata
    61981 ggcataactg acgtgctcta gtctaatttc tgtcattatt tcacaaattc gttggtgaag
    62041 cctttgtctg tcaagtcttc tttaaggata ccattttctt tatcccattt gtagaaagca
    62101 ttccagcgag ctgcgtcaaa ttgaccccat ttttccttgt cgcttgcgta ttcttttgac
    62161 aagtattttt gagattcgat gacaaagtca cgtttttcct tgagttcagg tgcattcttg
    62221 atgagaatat ctgcagcttc ttctggatgt tccatggcat attggtagcc ttttttgatg
    62281 gcttggatga ctttgcgagc ttcttctttg ttatctttca gatagtcgtt gtttgcgatg
    62341 ataactggtg aatagtagtc aaactccttg acatagtctt tcaagtacat gaagttagca
    62401 tctacacctt gagatttagc aaggatacca tcccaaccgt agtaaatcca agcagtatca
    62461 aagaccccat tggcaatcgg tgtgattgag tttgagtcgt tatttggtac tttttcaacc
    62521 ttctcaaagt ctccaccttg agattctacc aaggttttca acatagcaag ttcagttggg
    62581 tcattccatg tcccatattt cttaccaacc aagtcttttg gactgcttac attatcagat
    62641 ttacgagaga tgattcctga tgtattgtgt tcaacaatag ctgcaacggc agtgattcct
    62701 gctccttttt ccaatttctt agccatgtag tcttggaaat acactgcaaa tggtgccttt
    62761 ccgttgataa ccaagtcaga agaactttct tctggtggca atttcaaatc aacatccact
    62821 ccagcttctt tgaaataacc tttttccttg gcaacataaa gccctgtgtg gttggtattt
    62881 ggtgtccagt ctaggataaa gtcaaccttc ttaagttctg cctctttgtt gtctttagaa
    62941 gcagttcctt gaccacaggc cacaagcaca acagctacaa gagctgttac aagcgttaaa
    63001 aacactttcc atgttttctt cattttgatt tcctcttttc tttttcagaa acattctaat
    63061 tctacgaacg tttccattta ataacatatt tttcactaat atcgaccaac ttcataccca
    63121 aaaggctgat aatcgatacc agaataataa tagcgaacat ggtatcatac tgaaacaatt
    63181 tcttggactg aatcatataa acaccaagcc cctcaaagcc tcccaaccac tcagatacca
    63241 ctgttgtgat aaaagcgtag gagacactga ccctcagacc agcataaaag tagggcaggc
    63301 tgactggaat tttaaaatgc cacaggattt gccaaggctt ggcccgcatc agactaaaca
    63361 aggtcagcat atccttgtcg caatgcctaa aaccgtccaa aatgctgacg atgatgggaa
    63421 aggttgtcgt taagataatc aagacaatct tgggcaaaat cccataacct agccacaaga
    63481 ccaggatagg agctatggca atggtcggaa tggtctgaat gaccaccatc atagggtaaa
    63541 tcaggtcatt gagccaagtc aaactatcca tgagtacagc cataagacag gcaatcaaaa
    63601 ctcccaaaat cagccccagt aaagccactc tcaaggtcgc ccagctatgg tgccagagaa
    63661 attctctgtc acgaacaaag ggctggagaa tttcaagagg tgtcggcagg ataaacttgg
    63721 ggagaagttt aagaaaacct gctaactgcc agattgacaa gactccgaga aagcccaata
    63781 gactaatgtg tcgtctcagt atacttctca agtttctcat caatacttaa aatctctcct
    63841 acatttattt tgacattggc aaagacattg tctgccccct gccctgccac ttccagcgct
    63901 tcttttagaa tgcgcataag ctcatcaaac tccccttcca agaccgtttc aaatggtgtc
    63961 actaccatcg tcacttcttg agtttgcaga taagcaatga cctgatcaat aacagctatc
    64021 cgatcaatcc cctgtgctag gggtaaaact tgcaaggcaa tgcttgcttt cataagaacc
    64081 tcctcttctc gttttccttt ttaaaaaaag aaaaaccttt accatacatg gaaaaggtgc
    64141 aaaattagac taagtatcgt tccctccgct ggcattaccc agatcaggtg cggtcgaagt
    64201 ttaacacttc ctctcagact gtacacagac tcccatatat tatatgtata tatgatagcg
    64261 caaaataaga aaaatgtcaa ggaaactgct tacagaaaag agcaggaaat ttctcctact
    64321 ccaattttct atactcgttc tccatcactg tttactctgt agccatccac cgtcgtatta
    64381 acagctaagg cgcctgaaga gtaagaataa taccacttac cagagacctg gtaccagcct
    64441 gttttcattg cccctgaact acccagataa taccacgagc cattctcctt taaccatcct
    64501 gtctgcattt caccagataa tttcaaataa taccagctag aaccatcttt cagccatcct
    64561 gttgatttat aaccatttga tttgaaatga taccaactac catttatttt cttccaaccg
    64621 acagttgaac tattattgga tccatagcta gagatatttc ctgattgatt ctgataattt
    64681 tgtgaagaag tcactccctc tagctgtata tagcgacgac ttccgttata agccgtataa
    64741 ctcaaccact tgtagccgtc tttttcaagt atctgatcat aatgaacctt ctccccagga
    64801 taatagtaat caatcacagt tgcactaact aggggttcag ttttgatagc agacttggtc
    64861 ttaaaataat gagttccacc tgttgaagaa agaacagaat gacctagagg atttttattc
    64921 acagcctcca attgaacata acgatagctt ccattatagg cagtataact caaccacttg
    64981 tagccgtctt tttcgagaat ttgatcataa tgaaccttct ctccaggata atagtaatca
    65041 atcacagttg cactaactag gggttcagtt ttaatagcag acttggtctt aaaataatga
    65101 gttccgcctg ttgaagttga ggattgacta ttcccaacac tgccaccatc caaatcttta
    65161 aaatgaataa atcctgtcat cgtgtttgct tttataattc gtttattata ggattctgta
    65221 taaccatagt tatattcctc aatctcaatc tgatctccca ttacatttga cacccaggca
    65281 acatgaccat aagttcctgc agtagaccaa gtaatggaac caatcgtcgg tgtattatct
    65341 acacgataac cttcccgacg agcacgatgt ccccattcat tcgcatttcc ataagctgcc
    65401 ggcatttcaa aaccattgac attactcaaa cgaaaggcta caaaagaagt acactgacga
    65461 gaatacatgc gccactgatc aatttcctgg ctcccatttt tataataagc aggataatca
    65521 tccccacgcg caatcgatcc atttcctctg gaataggcat agacactatc accagctgct
    65581 agcatcaatc ctactactaa aaaaggaaca agctttttaa ctgacatctt caagtaataa
    65641 cttgttcctc ttgctataaa cggtaaaatt ttcattcttc ctccttgaaa aataatataa
    65701 agcgatgatt gccttcacct aaattattcg gagaaaaaag aaaaagtgag aaaatttctc
    65761 actttagtca agataatgaa tcaaattctt ttctgtaaga atatctgagt aagtaaagga
    65821 ttcaacgtaa acattaactt gtttatctcc ttccacatcc ccaaactcca caataaatag
    65881 ggatggataa acttcaatta gcttacccaa tctatttttt tggcgcttac gaccattctc
    65941 caaagtcatt tctacgactt gtccctcatg tgccttgatt tcttctttga tttttttcat
    66001 cttggctaca tctgtaaatg catctgacat cttatgcctc cctctttgag atacttgaaa
    66061 atttattgta ttctttttgg aaaatcaatt ccactgttcc acgagctcca ctacggtttt
    66121 tctcgataat aacttccacc ttattatttg ggataccttc ctcttcttca ccaccacgtt
    66181 catagtagtc atcgcgatag agaaaagcta cgatatcagc gtcctgctca atagacccag
    66241 attcacgaat atcagacaag accggtctct tgtcctgacg ttgttctaca ccacgagaaa
    66301 gctgactcag agcgattact ggaaccttca attccttggc tagtattttc aactgacgag
    66361 aaatttcaga aacttcttgt tgacgatttt ctcgaccagt tcccgtgata agttgcaaat
    66421 agtctatcaa aatcaaacca agatttccag tttcttgagc caatttacga gaacgagaac
    66481 gaatctctgt aatccgaata cctggcgtat catcgatata gatactggcg ttagctagat
    66541 taccctgagc aatagtatat ttttgccact cctcatctgt caattgccct gtacggatag
    66601 aatgtgactc cactaagcct tctgcagcta acatacgatc taccaagctt tccgcaccca
    66661 tttcgagtga aaaaatagca accgttttgt ccaacttagt cccaatgttc tgagcgatat
    66721 tcaaggcaaa tgctgtctta ccaactgctg gacgagctgc taagataatc aactcctcct
    66781 catgaagtcc tgttgtcata tgatccaaat cacgataacc tgtcgcaata cctgtaatat
    66841 cggtcgtttg ttgcgagcga gcttccagat ttccaaagtt gagattcaac acatctcgaa
    66901 tgttcttaaa cccgcttcga tttgcatttt cactgacatc aatcagccct ttttctgcct
    66961 gagcaataat ttcatcagct ggttgtgacg cttcgtaagc ttggttgaca gactctgtca
    67021 acttggcaat taaacgacgt agcattgctt tttctgcaac aatcttagca taatactccg
    67081 cattagcaga agttggcaca gaattgacaa tctcaaccaa gtaagacaag ccaccaatat
    67141 tctgtaaatc accttgatta tcaaggatag tacgaaccgt tgttgcatct atggcatcac
    67201 cacgatcgga taaatcgacc atggcttgga aaatcaaacg atgggcatac ttaaaaaagt
    67261 cccgagactc aatgtattct cgcacaaaaa caagtttact ctcatcaata aagatagccc
    67321 ctaaaacgga ttgctcagct aagatatctt gaggttgtac tcgtaactct tctacttctg
    67381 ccatcagact tcccttcctt ttacaatctt gtcaagaagg tgtaaactta tccttctttc
    67441 acacgaagat tgattacact tgtgatatct tgatagattt tcactggcac atcaatcaaa
    67501 ccaaccgctc gaatcggagc ttgtacttga atatgacgtt tatcaatctt aattccaaat
    67561 tgcttttgca attcttctgc aatcttctta ttggtaatag aaccaaaggt acgaccatct
    67621 ggaccaactt tttcaacaaa ttctacaaca gtttcttctg cttcaagttg tgctttaatt
    67681 gcttttcctt ctgcaatcat ctcagcgtga gctttttctt ccgatttttg tttaccacga
    67741 agttcaccta cagcttgagc agtcgcttct ttggctagat tctttttgat aagaaagttt
    67801 tgcgcatacc ctgttggtac ttccttaatt tcgccttttt taccttttcc tttaacatct
    67861 gctaaaaaga ttactttcat tcttctttct ccttttcctt tatttcattt aatacaattt
    67921 ctgtcagttt ttcacctgct tttgacaagg ttacatcttt aatttgagct gctgccaaat
    67981 taaagtggcc tccaccgcct aactcttcca taatccgttg tacattcagt ttactacgac
    68041 ttcgagctga gatagagata aatccttgtg tattcttcgc aagaacaaaa ctcgcttcaa
    68101 tacctgacat ggctaacatg gcatctgctg ccttactaat aacaactgta tcatagcatt
    68161 tcgtgtcctt agcctctgct attagtacat ctgaacctaa tttacgcccc tgtaaaataa
    68221 gttcattgac ctcacgatat tcttcaaaat ctgtcgcagc gatttcctgg atagcaatac
    68281 tatcacttcc gcgcgttctg agatagctag caacatcaaa tgtccgacta gttactcgcg
    68341 aggtgaaatt tttagtatcc aacatcatac cagccatcaa aacacttgct tgcatacgac
    68401 tcaaacgatt tttcttagaa ttctggaact gaatcaattc cgttaccaac tcactggcac
    68461 tacttgcacc actttcgata taagtaatga ccgcattatc tggaaaatcc tgatcccttc
    68521 tatggtggtc aataacaatg gtttgggtaa ataaatcata aaattctttt gataatgtta
    68581 aggctgtctt tgaatggtct acaagaatca acaaagaacg attggtcacc atccccattg
    68641 catccttaac agacaacaac ttcgtaactc cttctttttc tatgaatgaa acagctcgtt
    68701 caatatctgg agacatttgt tcttcatcat aaagagcata gctattttca atcacattgc
    68761 tggcgaacaa ctgcatacct acagcagagc ccaaagcatc catgtctaaa tttttgtgac
    68821 cgactacaaa aacctgatct acactccgaa tcttatctga aatagctgtc atcatagcgc
    68881 gcgtacgagt ccgtgtacgc ttgattgaag cagcagaccc accaccaaaa taaactggat
    68941 ttttcgtttc gtcgttttcc ttaacaacca cctggtcgcc accacgtact tcagccaagt
    69001 tcaaattgag caaagcaact ttccctatct catcatgatt tccatcgcca taagaaaatc
    69061 ccatacttaa ggtcaagggc aactgtctct gtttcgactc ttctctgaaa gcatcaataa
    69121 cagaaaattt atcattcatc aagccctcaa gcaccgtgta gtcagtaaat agataaaatc
    69181 gatccatact tacccgacga gaaaacatca tgtatttttc tgaaaactct gatataaaat
    69241 tagctacaaa actattgatt tgactaatat ctgactcaga agttgcatcc tccaaatcat
    69301 cataattatc cacagagaca atcccaatca ctggtcgact tgttaccaat tcatctgtta
    69361 tggcttgttc cctggataca tctacaaaat acaaaacacc ggaagaagca tccatatgaa
    69421 cagcataacg cttctcacca agcttggcat aagtagacgg atttcctact gaagccttaa
    69481 taatcgtttg aacagcttct aaatcaaaat caccatcttc cttggtcaaa atcaattcag
    69541 catagggatt aaaccactca acctctccag aagataaatt caatttcata acacctacag
    69601 gcatctgttc caatagagat gtcaaacttt cttccgcttg gtggtttaca tactgtatct
    69661 gttctacatc actccttgta taatgcactc tcagtttctt aaataaaaaa acatagcctc
    69721 ctacaaaaag aaacaaaatt aaaaccgtca acagattatt attaacaaaa ataatgaaag
    69781 tggataagac tccaaacgca atcaatccta ctagaatagg aaaaattgga cttacataaa
    69841 attttttcat tcaaaacctc ttggcaccca ttataccata atacccctca aaaagcgact
    69901 ttttaaaagt gtaatcagta attctatcaa ttataagaaa aaggtagttt acaattcagt
    69961 aaacctacct ttacacatat tgaaattaag attctttaac ctctaacaaa ccaatttcgc
    70021 catcctcacg acgataaatc acattggttg tctgatcttc aacatccaca tagataaaga
    70081 aatcatgccc caataaatcc atttgtagaa ttgcttcttc caaatccatt ggttttaaat
    70141 caatttgttt tgaacgaaca actttagact ggacaacatt tgaatcttcc accaaagcat
    70201 ctgtaaataa ttgaccagtt gctaccttat ttttattttt acgctcgatt tttgttttat
    70261 ttttacgaat ctgacgttca attttatcag ttacaaggtc aattgaacca tacatatctt
    70321 gagatacatc ttctgcgcgg agagtaatag atccaagcgg aatcgttact tccactttag
    70381 ccgttttttc acgataaact tttaagttaa ttcgggcatc caactcttgt tctggttgga
    70441 agtacttttc gatcttttcg agtttagaaa ctacataatc acgaattgct tctgttactt
    70501 ctaggttttc accacggata ctatatttaa tcatatgagt accttctttc taaacatttt
    70561 tgtttttatg attttattat aacgctttca ttctattttt gcaaattttt tcctcatctt
    70621 acaagggaaa atgtttttac atccttagca ccagcttctt ccaacagttt cttaacacga
    70681 tttatagttg ctcctgtagt atagatatca tctataagta ggattttttt aggaatagtg
    70741 actccacttt taataaagaa aggaagttct gtccccaagc gctctgaacg atttttagaa
    70801 gaactggctc tctcttctct tttctctaat aaatccagat actcaaaacc tgctgcctct
    70861 accaagccct caacctgatt aaatcctcta ttagcatatc tatcaggact taggggaatt
    70921 acaacaaatt gatactcttt gtactttttc aactcctcac ttaaaaatga agcgaaaact
    70981 tttcttaaca ggaagtctcc atcaaactta taccgactga aaaaatcctt catagcttga
    71041 ttgtaagtaa aaatcgctct atgactgact ccaactcctt ctttacacca aagttgacaa
    71101 tcttgacact ttgttgacaa ctctgttttc atacaatttg gacagttctc ttccccaatt
    71161 ctttcaaaag tagaatcaca gtctgaacaa agacaagagt catcattcct cagaagtaag
    71221 agactactaa aagttaaaac agtcttcata gtctgcccac ataacaagca cttcatagac
    71281 cagcctcctt attcatcatc tgaatttcct taatcgcctt cttgattgaa gcatttaacc
    71341 catcatggaa gaaaagcaaa tctcctgtcg gtctatccat gcttcgtcca actcgtccac
    71401 caatctgaat caaactagac ttggtaaaca aacgatgatt ggcctctact acgaaaacat
    71461 ccacacaagg gaaggtaact ccacgctcca agattgtcgt actgataagt attgtcagtt
    71521 ctccatctcg aaaagcttgt acttgctcta atcgatcctc tgttacagaa gatacaaagc
    71581 caattttctc atttggaaat tgctcctgta agatttcttc taactgctcc cctttcttaa
    71641 tttctgaagc aaaaatgagt aacggataag ctgtctttct ctgcttctca atataggact
    71701 ttaactttgg tgacaaacga ttcttgtcta agtagcgatt aaaatccgat aaccaaattg
    71761 gttttggaat aatcaacgga tttccatgaa accgtctcgg taaattcagt ctttttagtt
    71821 ctcctaaacg gaccttttta tctaactcat tggtcgaagt cgctgttaaa aagattctca
    71881 atccattctc ctttacacta ttcttgacag cgtggtaaag cattggatta tcaacataag
    71941 gaaaagcatc tacttcatcc actatcagca aatcaaaagc ttgataaaac ttcaataact
    72001 gatgggttgt tgcaacaact agtggtgttc gaaaataagg ttccgattct ccatgtagca
    72061 aagctatccc gcaagaaaaa tcctgttgca ggcgcttgta cagctccaaa caaacatcta
    72121 tgcgaggact agccaaacac actgcaccac ccgcattgat cactttagcc actacttgat
    72181 aaatcatttc tgtctttcca gctcctgtta ccgcatgaac taaggttggc ttttgcttgt
    72241 ctactgcttg aagcagtccc tctgacacct tctcttgaaa aggagttaat tggccgcgcc
    72301 atttgagaac atcttgcttc ggaaaatcct cctgcggaaa atagtataaa gtttgatcac
    72361 ttctgactcg cttcatcagc aagcactctc gacaatagta agcaccgatg ggcaaatacc
    72421 attcttctag aatagtacta ttacaacgtt gacagaaaag tttccccttc tcctttctca
    72481 ttgctggaag tttctccgcc aactgacgtt cttcttctgt taattcattc tcagtaaata
    72541 aacgaccgag ataatctaaa tttactttca tacttcttta ttcgtaaaaa ctagcacttt
    72601 agatgatttt ttagtacaat taaatcatgg aatttagaac aattaaagag gacgaccaag
    72661 tccaagaaga aatcaaaaaa tctcgcttta tctgccatgc caagcgtgtt tatagcgaag
    72721 aagaggctcg tgacttcatt actgccatca aaaaagaaca ctacaaagcg acacataact
    72781 gctctgcctt tattattgga gaacgtagtg aaattaaacg tacaagtgat gatggtgagc
    72841 ctagtggtac tgctggtgtt cccatgcttg gggtactaga aaatcacaat ctcaccaatg
    72901 tctgtgtggt cgtgacacgc tactttggtg gtattaaact aggcgctgga ggactaattc
    72961 gtgcttacgc cggcagtgtc gccttagctg tcaaagaaat tggtattatt gaaataaaag
    73021 aacaggctgg cattgctatt caaatgtctt atgctcagta ccaagagtac agtaacttcc
    73081 ttaaagaaca tgatctcatg gagctggata caaactttac agatcaagtc gatacgatga
    73141 tttatgttga taaagaagaa aaagaaacta ttaaagctgc acttgtggag ttttttaatg
    73201 gaaaagtcac tttaactgac caaggtttac gagaggttga agttcctgta aacttagtgt
    73261 aaacaatgaa taatacagcg tttcgttgac attctcacaa ctactttagc gagcaaaata
    73321 aaaagatgcg taccaaaata tactagaaaa tgaagcaatt caaacgaaac ctgatatcgt
    73381 tttccttcac acctatttac tagaattagc tgaacgcaat cacttgaaaa ttaatgactt
    73441 tgatctatga tatatagaaa tcctatcgct tcgataggat ttctatattt tacaaatggt
    73501 atggatagcg ttatactaaa gatatcttat acaaagaggt attcatatgt ctatttataa
    73561 caacattact gaattaatcg gtcaaacacc gattgttaaa cttaacaaca tcgtgccaga
    73621 aggtgctgca gacgtctata taaagcttga agcatttaat cctggttcat ctgtaaaaga
    73681 ccgtattgcc cttagcatga ttgaaaaagc tgaacaagat ggtattctga aacctggttc
    73741 tactattgtt gaagcaacaa gtggaaacac tggtattgga ctttcatggg taggtgctgc
    73801 taaagggtat aaagtcgtca tcgttatgcc tgaaactatg agtgtagaac gacgtaaaat
    73861 tatccaagct tatggtgctg aactcgtcct aactcctggt agcgagggaa tgaaaggtgc
    73921 tattgctaag gctcaagaaa tcgctgctga acgtgatggt ttccttcctc ttcaatttga
    73981 caatccagct aatccagaag tacacgaaag aacaacagga gctgagatac tagctgcttt
    74041 cggtaaagat ggattagatg cctttgttgc tggagtaggt accggtggaa cgatttctgg
    74101 tgtttctcat gcactcaaat cagaaaattc taacattcaa gtttttgcag tagaagcaga
    74161 tgaatctgct attctatctg gtgaaaaacc tggtcctcac aaaattcaag gtatctcagc
    74221 tggatttatt cctgatacac ttgatactaa agcctatgat ggtatcgttc gtgtaacatc
    74281 agatgacgct cttgcactcg gacgtgaaat tggtggaaaa gaaggcttcc ttgtagggat
    74341 ttcctcagct gcagctatct acggagccat cgaggttgcc aaaaaattag gtacaggtaa
    74401 aaaagtcctt gccctagcac cagataacgg tgaacgttat ctctctacag cactttatga
    74461 attgtaaccg tccaataacg aagtatattg aaaaatctcc agactagaga actcacggat
    74521 agttcctaat ctggagattt cttatttgca cttttcttgt acaactttag tccatggtaa
    74581 ataagcctct aaaacctctt tgtttacgag agtttccacg tttggaagac attctagaag
    74641 ataggataga tatttctcac tatttataat ggattgaaat aagatatgaa caaatcgatt
    74701 aggacatgat ggtaaagcgt aatcccttgt ttctcagctt tcccagacaa aaaagtccaa
    74761 tagtaagtca gctgactatc actctctagc accctataag aagtttcatc cgcatgaagt
    74821 aaggactgcg tcaatagtct ctctcgcaag aggttataaa ggggctccaa atagtattga
    74881 ctcgccttga tatgccaatt agcaatttcc ttacgtgtga ttggtaaacc catcttagcc
    74941 caatcttctt cttggcgata attgggtacc ttcagattaa acttctgatg gatggtgtga
    75001 gcgataatag aagctgagcc aaggctatgc gccaaagggg ctttaggaat aggagctttc
    75061 acaagcttat ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc
    75121 aagtacctta aagattccga ctaatattgg ttttaccttt attcctccat acacaccaga
    75181 gatgaacccc attgaacaag tgtggaaaga gattcgtaaa cgtggattta agaataaagc
    75241 ctttcaaact ttggaagatg tcatgaatca actccaagat gttatacaag gactggagaa
    75301 ggaggtgata aagtccatcg ttaatcggag atggactaga atgctttttg aaaacagatg
    75361 agtataaaaa gaaagtcctc atttcaatag aaatcacgac tttctgatgg atttatagta
    75421 aaatgaaata agaacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt
    75481 taaaagcaga ggtgtactat tctagtttca atctactata tttttggagt gatagaaaag
    75541 cccttcataa gctagtctac ttgttcaggt gcgagagctt tgacatcctt ttctgtactt
    75601 agccaagtca gttttccgtt ctcaaagcgt ttatatagta gccaaaatcc ttgaccatcc
    75661 cagtaaaggg ctttaaagcg gtctttacgt ccaccacaaa agagaaagac ttgaccggag
    75721 aaagaatcca attcaaagtg ggttttaact acataggcta atgagtctat tccctgcctc
    75781 atatctgtct tgccacaaac aaggtgaact tgacctaaat cacttagttg aattatcata
    75841 gtacaatacc tttcctccga taattatttt ttatctagta tactggaagt tggggaatta
    75901 ggatagatac cttgttatga cgcgcttact atgaatttta agtatagtct cctaaatgca
    75961 cttagccctt attatagggc tttttgtttt aattattcta atcgagtgag actggggaaa
    76021 aaacaatttc aggaaaaatc taagccctat acaaaaaagg aagcaatttg cttcctttct
    76081 attattagtt attcaaggct gctgccattg tagctgcaac ttcagcttcg aagtcgtttg
    76141 cagctttctc gataccttca ccaacttcaa agcgagcaaa ctcaactacc gaagcgttaa
    76201 ctgattcaag gtatgcttca actgtcttgc tgtcatccat gatgtaaact tgtgcaagaa
    76261 gtgtgtaagc ttggtcaact ttagtgttat caagcatgaa gcgatccatt ttacctggaa
    76321 taattttgtc ccagattttt tctggtttgc cttctgcagc caattcagct ttgatgtcag
    76381 cttcagcttg agcaataaca tcatcagtta attgagcttt tgatccatac ttcaagtgtg
    76441 gaagagctgg tttattaacc attgcacggc tttcgttgtc ttggtcgata acgtgattca
    76501 attgtgccaa ctcatcttta acgaattgct catccaattc tttgtaagaa agaactgttg
    76561 gtttcatcgc tgcgatgtgc attgacaatt gtttagcaag tgcttcgtct ccaccttcaa
    76621 caactgaaat aacaccgata cgtccaccgt tatgttggta tgctccaaag tgttgtgcgt
    76681 ctgttttttc aatcaatgca aagcgacgga atgagatttt ctctccgata gttgctgttg
    76741 cagatacgta tgcagcttca agagtttcac ctgaaggcat tatcaaagca agagcttctt
    76801 cattgttagc aggttttcct tcagcaatga ctttagctgt agtatttacc aattcaacga
    76861 attgagcgtt ttttgcaacg aagtcagttt cagcgtttac ttcaataact gctgcaacat
    76921 taccgttaac ataaacacca gtcaaacctt ctgcagcaac acggtcagct ttcttagctg
    76981 ccttagccat acctttttca cgaagcaatt caatcgcttt ttcgatgtca ccgtctgttt
    77041 ctacaagcgc ttttttagcg tccataacac cggcaccaga tttttcacgc aactctttta
    77101 caagtttagc tgtaatttct gccattttaa ttctcctata ttttttgaaa ataggagagc
    77161 cgggctaagc cccgccctcc taggtaatta ctatttgtat aaattaagcg ttgtcacctt
    77221 ctacaacttc aacgatttct tcaattgaat ctgcttgagt ttctgaagct gcaaattctg
    77281 cttcaactgc tactgcatcc tcaccttgac gtccttcgat aatagcgtca gccaatttag
    77341 ctgtgatcaa tttaacagca cggatagcgt catcgttagc tgggatgatt acatcgatat
    77401 catctggatc agtattggtg tcaaccatcg ctacaactgg gattcccaat tttttagctt
    77461 ctttaacagc gatttgctct ttatgtgggt caactacgta catcacatct gggatacgag
    77521 gcatatcttc gataccaccc aagaattttt caagacgcgc acgttgtttg ttaagaagtg
    77581 caacttcttt cttaggaaga acttcgaaag ttccatcttc ttccatacgt ttaatttctt
    77641 tcaaacgagc gatacgtttt tggattgttc cccagtttgt aagagttcca cccaaccaac
    77701 ggtggttgat gaagtattga cctgaacgta ctgcttcttc agcaactgca tcagctgctt
    77761 gtttcttagt accaacgaac aatacaactg catcgttagc tgctgcatca cgcatgaagt
    77821 cgtatgcttg gtcagcgtat tttacagttt gttgcaagtc gataacgtgg attccgttac
    77881 gttcagtaaa gatgtactta gccatcttag gattccagcg acgagtttgg tgaccaaagt
    77941 gtacaccagc ctcaagaagt tgtttcattg aaattactgc catgagtatt tctccttttt
    78001 gtttttttcc tcttcttgac ttcaactcgc aaaacgaccc aagggcaact gcttcacaat
    78061 tcatcaagaa tgagtattat cgttcacacg acaattttca ttctaccata cttttccaat
    78121 attttcaagc tattttgata taatttttaa tagggattgt cacggtaaaa cctgaaaaga
    78181 gggctctatt cgagtccctc tgtaaattaa tctgcataaa tatatgtaac aaaaccttca
    78241 gaagttgttg ttggattgaa ccatccacgg tgatttccaa ttgtacgatt acctgcataa
    78301 tttgattctg atacttggat acgtgttgtt gattcaacag ctgtaacaac cgctacgtga
    78361 ccatatccac catcattcca acatgcaatt gctccaactt gaggtgttga acctgtacgg
    78421 aaacctgctg ctgctgcact tgtagcccac tgtgctccat taccccagta gtctccagcc
    78481 caaggtgcca atgtttttac tccccatgta cattctccaa ttggataact tgaagcgttt
    78541 gtactgtatg ttggacgaac ttttgcacgg acaggtgctg ctgcagattc agatactgct
    78601 tgcacttgag ctgttaagtt agtgtttgct gaagcaagta ctgattgttg ttggctagct
    78661 cgtttttctt tataagctgc ttctgctacc gcagctgcac gagcctctgc ctcagctgct
    78721 gctttttgct ctaatagact tgctttttcc ccttcagctg tcgctttctc agcagcaaga
    78781 cttaattcag cagcttttag ttctgcctgt ttcgtagtca atgcttgagc atcatcagcc
    78841 aatttttgtt gattagcaat tacagtattg atagcatcat tatttgctac ttgtttttca
    78901 gaaatagctt ttttatctgc cttttgttgt tctaacattt tgttgtttgc agatacgatt
    78961 tcactcattg cagcaacacg tgaaatagct tctgtaattg attttgagtt tacaatggta
    79021 ttgatatagc tagttacggc tccatttgtt tgagcactac gagcttgttt ttccaacgat
    79081 tggttacgag aaacaatgtt tttagaaagt tctgtaatct caccctcgag tttcttagat
    79141 tctgcttgta atctatcatt ttcagcttgc aagttagact gctcagcttg aatagctgat
    79201 acttgctcct gaatttggtc aacttgtttt tgggcttctt gttgttgtgc tgttaagtta
    79261 ctaattttat tatcttgagc agcaattttg tcatcagtcg tttctgcatg cgcagttgtt
    79321 aaaacagcta cttgagaaac cattactgta cttaataaaa gtgacgctaa gatttttttc
    79381 ttcatattac gtagatactc cttcttttaa agacaatact agtataccaa aaaaaggcct
    79441 aataaatatt acgcctttgt tacatttata tgtcgttctt atagataata tttttcaaaa
    79501 ataaattgaa aaacagtaat ccataaaaaa tttaaaatca tcgtcggtac caagctatag
    79561 actataaaaa tcgacatgct atctactgtc aaccctacca taaaagccaa aagataacta
    79621 cccatttcaa acaggaatgt cagcacaatc atagctagca ttcttgtcca acgattcaac
    79681 aaaataacac tattcaattt atgaaggaag gctcccaata agataaataa gagagttgta
    79741 atccctatta gatggaaaaa gtaaacatca taaaccaagc ctataacaaa acaatagact
    79801 aggtagagat actctgatac ttctatcgtc tcaaataaga gaaatagaaa aagaaaatga
    79861 ctagccaaat gtacatgggg gaaaaatgag cccagaagct ggctaatatg ggcgtcaatt
    79921 agaacaaaga aaggaagcaa taaaaatact ccaactcgct tcaactgtct cattatgaat
    79981 tccccactaa ttctatcaca tctacattat gagtatctgc actcaattta acagttactt
    80041 ctcgtgtcaa atagtctgta ctatgcgttg tggcaaccac ttcaccaaca ggaatatcag
    80101 caacgttaaa gtttcctaat ccaccagtag tcaccttatc tcccgcacta atatcgctat
    80161 tactatttaa ttggctaatt ttaagaacgt cattttcctt gtcatagcca ataataattc
    80221 cataaattgt agtagagcca tgttgaattt taacagaaat cttatcagca ttttccgtat
    80281 ttgtcagaag gttgactata gtagagttct cctctacttt tgaaacactc ccaatcaagc
    80341 caccatttgc aatagctaac atgttctcag aagcaccttt tgatctacct gcatctaagg
    80401 tcaactcctg cttccaagat accggagaac gcataataac atctgctgct aaagtctttg
    80461 tggcttgcaa tttagacttc atatcaagca attggcgcag ttgttcattt tctgtcttta
    80521 aactttccac ctcatttgat ttaacttcta attggtaaag ctgtttcttc aaactttcat
    80581 tttcattata tgttcgtgtc aaatgagcca aatctgattt gacagaatca aaccactgaa
    80641 aaggtttttg tacaactcta tcaaccaatg agattccatc tcctaatttt gtcacaattg
    80701 tacttgaata agttgtcgct aagagagctg acacaagcag aacagtgaca aaaacaataa
    80761 tgacatattt tgatttttta aaacggttca tatccctacc tttatatcaa aaactgttac
    80821 agtaactttt tatcaattcc tgaaagctac taagatttta agaaaaataa acaacaacca
    80881 agtacgagaa taacaagaat ggtcagcgta tcctttagag tccatttcaa ttgtcggtat
    80941 tgacttctgc cttttccacc ctgatagcca cgcgcttcca tagcgatagc caaggaatct
    81001 gcacgtttta aacttgtcgc aaaaagagga atcaaaatgg gaatcatcga ctttactttt
    81061 tgaacgatgc ttccttctcc aaaatccact ccacgagctt tctgtgcatt cataatccgc
    81121 gtcgtatcat ccatcaaggt tgggacaaaa cgcaaactca tagacagcat caatccaatt
    81181 tcatgaactg gaactttcac acgctttaaa ggtgctaata aagcttcgac agctgatgcc
    81241 aaacttaaag gcatggttgt taaggttaac aaagttgaaa agaaaataat caatacaaag
    81301 cgacaaaaaa taatcccagc ttgttgcaaa gcataatccg tgattctcac aaacgaaaac
    81361 tcaaataaaa cattcccatt agaaatgaaa aatagttgaa aaatagttgt gaaggcaatc
    81421 aagaaaaaca tagacttcaa gccctgaata aaaaatgaaa gagatactcc tgacaaggca
    81481 ataaatatcc ctgtcgctat aaaaagaatc agattcgtca aggggttatt agcccaaaac
    81541 acaatcaaaa tcagtagcat catagcaagc aatttgctac gtggatccaa tcggtgaaca
    81601 atcgaatccc ctgggatata acgccctaaa atcatactat ccatttagcg actccttgaa
    81661 ctcctctatc ttaatcggta atcgtttaaa tgacacgcct ctatcagcca atcgtttaca
    81721 aaaggccgta attttaggta ctcccaactg aacttcttcc ataaaaacaa cgtcttgaaa
    81781 gacatcactt ggtttgcccc cctttactaa acgtcccttt tccattacat agacttgatt
    81841 cgcatattca gcaacatcat ccatcaaatg cgttaccaag acgatggtca tccctgactg
    81901 gtggagtttt ttgaacaggg tcatcaactc ctttctccct agaggatcta gaccagctgt
    81961 tggctcatct aagactaata tagctggctc catggcaagt atgcctgcaa tggcaacacg
    82021 tctcatttgt ccccctgaca gctcaaacgg actacgatca aaaagtgatt catcaattcc
    82081 aaccagagcc agtttctcac gcgcagtctt cacagcatct tcttcagaaa ctccaaaatt
    82141 ttgcggtcca aaagcaacgt ccttcaaaac cgtttcttca aaaatctgat tttcagcaaa
    82201 ctgaaatacc aagccaacct gttttctaat ttgacgaata tctttatttt tagaagtcga
    82261 ggtgattaag gtatcaaaaa ccctcacact cccttgactt ggcaccaata aaccatttaa
    82321 gagttgtaaa atagttgatt taccactacc tgtgtgccca attaaagctg tataagagcc
    82381 atcttcaatc gtcaaagaaa catccgacaa agctgctgaa gctaagggag taccttcttg
    82441 atatgtaaaa ttcacatttt ctagagcaat tcccatagct tatcctctag ctcactttct
    82501 gtcaaataat tttcaggtaa attatagcca ttatggctca aagatttttt taattgatta
    82561 gcaaaaggat cgtctaatcc aatttgatct aaatcatttc gagagaaaag ctcccttgga
    82621 ctactagttg attcaatttc cccttttttc atgaccaata cgcgatcact catggcgact
    82681 tcttccaaat catgggtaat agaaatgacc gtcatatcat agtcttttcg aattcctttt
    82741 actgtcccaa taagttctct acgcccctca ggatccaaca tactcgttgc ttcatctaag
    82801 attaaaatag ctggtcttag gactacaaca cctgcaatgg ccacacgttg cttttggcca
    82861 cctgatagac gcgctggctc tctcttttta aagtccaaca tgccaactaa atccagagct
    82921 tcttctactc tctttttcat ttcttgacga gaaagtccct gattttccaa accaaaagca
    82981 acatcatctt caacagtcgc tccaacaaat tgattgtctg gattttgaaa aaccataccg
    83041 atttgacgac gtatattcca aacattttcc tcagtcaaac gttggccatc aattacaatc
    83101 tctccggatt ctgcttccag taagccatca attaatcgaa ccgtcgttga tttaccacta
    83161 ccattatgcc ctacaatcga aagccattct ccacgtttca cgtgaaacgt aatatccttc
    83221 acatcgtagt agttctgatt ttctttatag cgaaaagaaa gattttttac atcaattatt
    83281 gatttcattt cgaaccaaat gtccctttaa atacataggc actacccttg aaatagtcat
    83341 agccagagta gatagtgaaa aataaggcta cataaagtag aacttgacca agcaaagtcc
    83401 aatgtaatag caagaaaata atggcaaaca tctgactaaa agttttaatt tttccaggca
    83461 ttgctgctgc taaaattgtt ccaccagttt caaccaataa aagccttaaa cctgtcacag
    83521 ctaactcacg acagataatc actgcaacaa tccaagccgg agccatacct aactcaatca
    83581 acataataaa agccgacata actagtaact tatccgccat aggatctgca aatttaccaa
    83641 aattactgac cacattccat ttacgagcta aatatccatc taaatagtcg gtaatactgg
    83701 caacagcaaa gataatagct gcaactatat gactctctat cgaatttcct atcgttaaaa
    83761 taaagataaa aataggtata aagagaattc gacctattgt taagagattg ggaatttgtt
    83821 cttttttcat tcgtttttcc ttaattttta gtaaaggtta cagtgatttg tccagtctga
    83881 gctgttaatt tcgataaatc aacagtctga ttatctactg tcaaatcaac accttttaca
    83941 acacctaacg taattgttac aggactttta gttgcaactg ttgcttctgc acttttcttc
    84001 tttggcgata aggttacacc gccctcaagt tcgctttctg aaacactgac ccaacttgta
    84061 acatctgaaa ctgccaattg caatttaact gtttccttac ttgtcttata agcgatttct
    84121 acatgatttc cttcgcctga tacacttata gctgattcta tactagaaga actactactt
    84181 gaggagtggg gaacagagct agttgaactt gttgattgaa ccacactgta attagaaaga
    84241 gaaggctcct ctggttgagt ttgaatatag ttccaaacat aataagtcac aaaaattaaa
    84301 atcgataaag caaaaaggat aaaataaaat aaaggtaaaa atgatgtttt tttcttcttt
    84361 ttcttacttg aacgtctacg acctgtcaac tcatcttcat caacatctac ttcctcataa
    84421 gtaatcatac tcccagaatc ataagcatcc aaaacaattt ggtcatctaa ctcaacagcc
    84481 catgcatatt ttttcaagaa agaacgcgtg taaaaaggac ttggaagttg atcgaaatcg
    84541 tctgcttcca ttgcttccaa catatctaac tggatttctg tctttttctg caattcatct
    84601 aaactcaatc cctgattgat tctagctaat cgtaaaacct ctccaattgt tttttttctc
    84661 atacttgtca tcccttcttt ctagtgtcta ttataatagg ttactacgat gggaatattg
    84721 taaaatcaac tatgtcacca tcatctatta aatgatgtcc agcatcaagg acatcctcta
    84781 aagtaatttc ctgtaaaatt ttcggcaaat caaaaattgt ctcaccattt tcaaaagcat
    84841 catattgcgt tgcaataaat tcaagagagt tcatgctact gaaaaattcg ccaaacatct
    84901 ctcttttgat aatatctaaa tgttcctctg taatatctaa atcctttgta aaattacgaa
    84961 tagccttcct aaattgatga gacaaagcaa ctggctcttt cgtatccatt gtcaacatga
    85021 caaaatgaaa gcgacttgtt acttcaactt ccagagataa ggatgcatca attttacctg
    85081 attcataaca tttttgaaaa cgatccgaag tccaaccaaa catcattgca aacaataact
    85141 ttaataaaat atgatgtcga tagcaatccg cttcagaaac ttctcgctta cctctaactc
    85201 caatcgctag tttgggagaa gatacttcca ttctcatact atctgttggc tttacaggct
    85261 gtaaaaacaa cttttctctt gctacttcct gaaaatctga atctttcagt tctttgcttt
    85321 caaaatagtc ctgtactcgc tccacatcaa aattaccaac taaaaacaga gacatgttta
    85381 caggtttgta aaactttgta aaattttctt gcaaattagt tagattgatt tgggaaatgg
    85441 actcctcact tccaactata tcagttgcta aaggtgtacc aggatacaaa ttcgctaaag
    85501 ttgaaaagaa taaacacgaa tctggatcat cttggtacat ttctcgttct tgctgaataa
    85561 tatcctgctc tgtcagaatg gaagcttcag taaagtgtgc tgatgttacc aattcatcaa
    85621 gtaaatctaa attttctaaa aaataatccg ttgctgaaaa aagatagttt gtttttgtaa
    85681 agcttgtaaa ggcattacta tctgcaccta gactcgtaaa agccgacatc aaatcactag
    85741 aatcttctct ctcaaataat ttatgttcaa gaaaatgagc aattcctcca ggatattgtt
    85801 ttacatctcc gtcaacttct gtgacaaacg tatctaccga accaaactgt acagtgacac
    85861 tcccgtaaac ctctttaaat tcctttttag gcaaaagagc aactatcaat ccattggcca
    85921 aacgagttcg ataaaccttt tcttttacag ctggatagta tttttcttca aaaacaacct
    85981 ttgtcattct attccttcca taaagtaaat cgcttgtagt ttcacattat tagctactct
    86041 acaaatagca tctttgtcaa tctgttcaag ctttacaatc caacttttaa agtctgctga
    86101 agattttcca aataaggcat tttgataagc acgttcaatc aatgaagatt gattatctta
    86161 agaaagtaac aacgaccaac gaatcatttc cttggtctga tttaactcaa actctgtaaa
    86221 ataacctttt tttaaatcaa gcagttgatt attcatcatt ttacgagcct ggttacgatt
    86281 ttctcgattg ataccagcat acatcctcaa gaatccacta aataaatcaa gctcacttga
    86341 aatggtataa gctaatccag cattttcacg gacatttgta aagagcttag aatgagcaaa
    86401 tccaccaagt aaaccattca ttacaatcat gggtaaatgt tgctcatcac catatttaga
    86461 acggtaatga taacctaatt ccaaaatgga ttgtcccaca tttttccgaa ccataccttc
    86521 ctgaaggata ttagaataag gttgacaata ctgaaccttc acatctcctt ttcgaccttt
    86581 aaagccaaat gattctaata cattttgaat ttcaacctca ttaaaatcac ctaggaaaaa
    86641 gaaatctatt cgatcattgg ctaaaaattc ttggaaacaa gaataagaac tttgtggagt
    86701 ttcagctaaa atacgatttc gtaaatcact atattccaat tgaagacgtt catcatgaaa
    86761 aaacaattta tccaattctt tatgtgcaaa ataaaaagaa tcatccatat cagctgctaa
    86821 acttgctagc aattgttttt tctcaatttc aaataaggcc ggatcaaacc cattatcaac
    86881 tactacgggt gaaaaaagag tttcttttac aagttccaaa atctgagagg ttagcacgtt
    86941 tttcctactt aaaaactcat cacgaacata ggtaaatgtc aattctataa tgtggctttg
    87001 ccctcttctg aaacaattgg ttgacatatc tgtaccgtat agactggcca agtgtctcct
    87061 caaatcttga gaagtggggt acatctgatt agcagtctct agcatacttg cactcaacat
    87121 gtgacctgca atcgtatcaa gggataatgg agcggtaaaa cgcacggtaa ttttgtttgt
    87181 tttaaacttt tttgattgga taaaatgtgt tgaaattcca tgcactaact ccatgattta
    87241 cctccttata tacagacttc tattatatca cgaaaacctg aaattttctt attccctgta
    87301 acacttttga aataaaaatc gcttacattt ctctctgtct ctctcactat ttttaggaaa
    87361 atatggtata ataccaaaga ttgaggtgaa ttatggaata caaattattt gaagaattta
    87421 ttaccctcca agcactactc aaagaacttg gaattacaca tagcggagga gctattaaat
    87481 catttctctc tgaacattct gtttacttta atagggaatt agagagtcgt cgtggaaaaa
    87541 aacttcgtat tggcgataaa gttgacatcc ctgacatgaa cattgacatc ttgttgacac
    87601 aacctacttc tgaagaacaa gatgaatacc aagctgataa agttgaaaaa gaacggatcg
    87661 ctaaacttgt caaaaagatg aataagggag ttaaaaaaga caaatcgaaa cctgcttcat
    87721 cacctaaaag ccaacaagct ccacgattcc ctggtagata atcatgtggc tacaacatct
    87781 atctctcaag acttttcgta attacaaaga aacgaaaata gactttaatc ctaaattgaa
    87841 tgtctttttg ggacgtaatg cacaaggaaa aacaaacatg ttagaggcta tctatttttt
    87901 agccttaacg cgtagtcatc gaactcgaac agataaaaat ctcattcatt ttgatgagga
    87961 acaacttcat ctttcaggtc tcgttcagaa aaaaactgga tccattcccc tagaaatcga
    88021 actaacacaa aaaggccgtg taacaaaagt taatcactta aaacaggcac gcctttcaga
    88081 ttatgtagga cacatgaatg ttgtcttatt tgctcctgaa gatttacaac taattaaagg
    88141 agcaccttcg attcgacgaa aattcattga tatggaactt gggcaaatta agccaatcta
    88201 cttatctgac ttaaccaatt ataaccacat cctaaagcaa agaaacactt acctaaaatc
    88261 agatcaaaaa atagatgaaa cattcctttc tgtgttagat gatcagctag ttgattatgg
    88321 atgtcgtgta atgaatcacc gcttagattt cataaaaaaa ctagaatcat ttgggcgtaa
    88381 gaaacatttt gaactctcta atcagatcga agagttgtca atatcctatc aatcttctgt
    88441 caatataact gacaaacaaa acttatccga atctttcaaa attgctttag aaaaaagtaa
    88501 atccagagat ttatttaaaa agaatactgg tgtcggtcct catcgagatg acatttcttt
    88561 ttatataaat gggatggatg ctagtttcgg aagccaaggt caacatcgta gtctcgtcct
    88621 ctcgataaaa ttagcagaaa tcgaattaat ggaaagcatt accacagaat ctccgatatt
    88681 actgcttgac gatgtgatga gtgaacttga caacactaga cagttaaaat tattagaaac
    88741 gatttctcaa tcaatccaaa cctttatcac aacaacaagc ttagaccatc ttcaaaatct
    88801 gccagaaaat ctaagtatct tcactattca ggatggtaaa gctgctgtaa atggaaattg
    88861 acaacattat aaaagaactc ctgttttcac tggagttctt ttcattgttt tttacataga
    88921 ataatttggt gcctcattag taatttgcac atcatgagga tggctttctt tcaaaccagc
    88981 accagacatt tcaataaatt gagcattatc gtgtagttct ttaaggttag ctgcaccaca
    89041 gtaacccata ccagagcgaa taccaccaat catttggaaa acaatatcag ctgccgctcc
    89101 tttataagca acacgacctt caattccttc tggaacaagc ttgtttgctt cattgacaga
    89161 accttggaaa taacggtcgc ttgaaccttt cttcatagca gcaattgatc ccataccacg
    89221 gtaagtcttg aatttacgtc cttggaagat ttcagtttcg cctggagctt catcagttcc
    89281 agcaaacata gatccaagca taacagcatt tccacctgca gcaagtgctt ttacaatatc
    89341 tccagaatac ttgatcccac cgtcagcaat aatcgtttta ccatattcgc gcgcaacagc
    89401 tgcagcatcg tagatagctg ttacttgcgg aacaccaaca ccagcaatca cacgagtagt
    89461 acagatagaa cctggtccaa taccaacctt aacaacgtct acacccgctt cataaagggc
    89521 acgtgcacct tcagcagtag caatatttcc agcaatcaaa gtccgatctg ggaaatgagc
    89581 acgaatctcg gcaattttac gcaagacacc tgcagaatga ccatgtgcag tatcaataac
    89641 aatcgcatcc gctcctgcct caaaaagagc ctctgcacgt tcaaatgtat ctgaagtaac
    89701 acctactgca cctgcaacta gaagacgacc aaactcatct ttagccgcat ttggaaactc
    89761 aataactttt tcaatatctt tgatagtgat caaaccagaa agactgcctt cttcatcgac
    89821 caacggaagt ttttcaatac gatgctcttg aagaatactc tcagccgttg caagatccgt
    89881 acccacagga gcagtaacaa gattttcact agtcatatgg tttgaaattg gttgattata
    89941 atctgaaata aaacgaagat ctcggtttgt caaaatacca accaatttac gattttcaag
    90001 tgtttcaaca actggaacac cactgatgcg gtaacgaccc ataagctcat ctgcttcagc
    90061 aattgtatgt tcaggcgtca agaagaacgg atcaataata actccatttt cagaacgttt
    90121 taccttacga acctcgtctg cttgttgagc aattgacatg tttttatgga taactccgag
    90181 accacctgca cgagcaatag caatggccat ttgactctct gtaactgtgt ccatggcagc
    90241 ggtaataatt gggatattta aagtcaaatt atctgccaat ttagttgtta aatctgcatc
    90301 gttaggcaac acatgacttt cagctggaat aagcaataca tcatcaaagg taaaaccttt
    90361 tttcaaaaat ttagtgtccc aattagacat tcgaagtttc ctcttttctt tctttttgag
    90421 cttgactctt tttatattgt atctatcata ccattctata caaatttgtc aaatgttaca
    90481 ggggtaaata aaaaactatc ttttcttcga gatagaaatg atagtttctt gtaaaataaa
    90541 cttagttaaa gtaatgaagt cccattgccc cttttacctc agatagggtt tgacccgcaa
    90601 cttcacgcgc tctttcacta cctttttgaa tcatattata aacttctccc atatccttag
    90661 caaattcaat acggcgctca cgaataggac ccagttcacg ttctaatatt tcaagtagat
    90721 aacgcttggt cttcacatca ccaagaccac ctcgttgata acgttctttc atatcagcaa
    90781 tttcttgagc atcttctgga cgaccaaaaa catctagata atggaaaacc atatttccct
    90841 caatcttacc tggatcctca acgcggatat gatctggatc tgtatacata ctcattactt
    90901 ttttacgcaa agtatccgca tcatcagcta aataaatacc attatttagt gatttagaca
    90961 ttttagcatt tccatctaaa ccaggcaaac gccctgctct ctcattttct ggataaatac
    91021 cttccggctc taccaagaca tcacagttat atgcattgtt aaaagaacga acaatttcac
    91081 gagtttgctc aatcattggt ttctgatctg tcccaacagg aacataatta gccttgaaag
    91141 ctgtgatatc agctgcttga gcgattggat agaccaagaa tcctgtcgga atgctttctc
    91201 caaatccttt ctgagaaatc tctgtcttga ctgttggatt tcgctccaaa cgtgctaacg
    91261 aaactagatt catataatac atagacaact cagccaactc tggaatctgg ctttgaataa
    91321 aaatagttga cttatttgga tccaatccaa ctgcaagata atccaaagcc acatttccga
    91381 tagactctac aatggtttga ggatctttgg catgatctgt caaggcttgt tggtcagcca
    91441 agaacacaaa catatcatac ttatcctctt cctgtaataa tactcgattt ttgagacttc
    91501 caacataatg tccaatatgc aattttcctg ttggacggtc tcctgttaaa ataatgggtt
    91561 tagtcatttt gttctccttc gatatagtcc tttcaattat agcatttttt taatgaaata
    91621 accgtaattt atcaaaataa atcagccttg ctttttacag atttgtgtaa aggatactgt
    91681 aaatataatt tacacaaaat tgacaaataa aaatttgaat atttctgtat tttctagtag
    91741 aataaatata ttacacatat aggagaaaaa tattgcttac agtatctgat gtttcactac
    91801 gttttagtga tcgcaaactt tttgatgatg tcaatatcaa atttacagaa ggaaatactt
    91861 acggattaat cggtgctaat ggtgccggaa aatcaacctt tttaaaaatt ttagctggag
    91921 atatcgaacc tactactggt cacatctctc ttggtccaga tgaacgtctc tctgttcttc
    91981 gtcaaaatca ctttgactac gaagatgaac gtgccattga tgtcgttatc atgggaaatg
    92041 aaaaacttta tagcatcatg aaagagaaag atgctatcta catgaaggaa gatttctcag
    92101 acgaggacgg ggttcgtgct gccgaactcg aaggagagtt tgccgaactt ggaggttggg
    92161 aagcagagag tgaagcctct caactacttc aaaacctaaa cattccagaa gaattacact
    92221 accaaaacat gagcgaattg gccaacggtg aaaaagtaaa ggttctcctc gccaaagcac
    92281 tttttggtaa accagatgtt cttctcttgg acgagcctac taacggtttg gatatccaat
    92341 cgattacttg gttagaagac ttcttaattg actttgataa cacagttatc atagtatccc
    92401 acgaccgtca cttcttaaac aaagtttgta ctcacatggc cgaccttgac tttggaaaaa
    92461 tcaaactcta tgtcggaaac tacgacttct ggaaggaatc ttctgagctt gctgctaaat
    92521 tgctagcaga ccgtaatgct aaagcagaag aaaaaattaa acaattgcaa gaattcgttg
    92581 ctcgtttctc tgccaatgct tctaagtcaa ggcaggcaac atcacgtaag aaaatgcttg
    92641 ataagattga gctagaagag attgtgccat ctagtcgtaa atatccattt atcaacttta
    92701 aagcggaacg tgagattggt aatgatctct tgacagtaga aaatctaact gtaaagattg
    92761 atggtgaaac tatcttggat aatattagtt tcatcttgcg tccagatgat aagacagcac
    92821 ttattggaca aaatgatatt caaacgactg cattaattcg tgcaatcatg ggagatattg
    92881 actatgaagg aactgtcaag tggggagtta caactagtca atcttaccta ccaaaagata
    92941 actcagctga ttttgcagga ggagaatcaa ttcttgactg gttgcgtcaa ttcgcaagta
    93001 aagaagaaga tgacaatact ttcctacgtg gcttcctcgg ccgtatgctc ttctctggag
    93061 atgaagttaa caaacctgta aatgtcttgt cagggggaga aaaagttcgt gtcatgcttt
    93121 caaaactcat gctcttaaaa tcaaatgtcc ttgtacttga tgatccaaca aatcacttgg
    93181 acttggaatc tatctcaagc ttgaatgatg gattgaaaaa ctttaaagaa tcaatcatct
    93241 ttgctagcca tgaccacgaa tttattcaaa ctttggctaa ccatatcatt gtcttatcta
    93301 aaaatggcgt cattgaccgt atcgatgaaa cctacgatga attcctagaa aatgcagaag
    93361 tacaagcaaa agttaaagaa ctttggaaag actaaataaa acttcaaaac tcagttgggt
    93421 taaccaactg agttttctat cattctacga ggtaacatga aatcattttt aaaaacatat
    93481 cgaacctatt ttatttcttt catcattcct gtagtgatta tgtctggagt atatctatct
    93541 caaggtatct actggaatag cgacaactct cctctattag gagatggctt tcatcaatac
    93601 gttatttttg atgtagcctt acgaaatatc ctacatggaa atagtagtct gttttacacc
    93661 tttacaagtg gtctagggct aaacttctat gccctatcta gttattactt gggtagtttt
    93721 ctcgcgcctc tagtttactt ttttgatcta acgaatatgc cagatgctgt ctatctgacc
    93781 actctcttaa aatttggatt gattggtctg tcaacctttt ttaatttgaa taaattgttt
    93841 caatctatcc ctcagacttt aaaactagcc ttatctactt cctatgctct gatgagtttc
    93901 actgtcagtc aattagagat aaaaacctgg ctagatgttt ttatcttgat tcctttaatt
    93961 ataactggtt tacatctact gataactgaa aagaaactcc tattgtactt tacaagtctg
    94021 tcaatcttat ttattcaaaa ttattatttt ggatatatga cagtattgtt tcttattttc
    94081 tggtatctct gtcaaatttc gtgggacttt aagactcgaa aatcatctgt tcttgatttc
    94141 atagttatct cctttttagc tggtatggct agtttgatta tgactcttcc cactctattt
    94201 gatttacaga cacatgggga aaaattgact gaagttacaa agtttcaaac tgaaagtagc
    94261 tggtatcttg atctctttgc taagcaattc attggttcct ttgacacaac aaagtatggg
    94321 gccatcccaa tgatttttgt tggactattt ccctttattt tgaccatttt attttttacg
    94381 ctgaaatcta ttaagtttca cgtgaaactc atatatgtaa tattctttgc atttctaatt
    94441 gcaagctttt acatagaagc tcttgactta ttttggcaag gcatgcatac tccaaacatg
    94501 tttttacatc gctatgcttg gattttctct accttgttaa tttacacagc agcagaagtc
    94561 ttaaagcgtc tgaaagaact taaagtctgg aattttttag tttcgctttt tcttgtagta
    94621 gcaggatttt tagctaccat ctatctaaaa tcgcattatt cttttttaac agatttgaat
    94681 attctgctta ctcttgaatt tttggttgtc tattctcttt tactccttgc agttatcaaa
    94741 aagtttatat ctgtgaatct atttgccatt ctaatctctt tatttatact ggttgaaatg
    94801 agtttaaatg cttcatctca aatggacgga attgctaagg aatggggatt tgcttctcga
    94861 agtgcttata gtcgagatat cccagctatg gaatctttct caacatatat tggaaatcaa
    94921 tttactcgta ctgaaaaact acaaactcag acaggaaatg acagtatgaa attcaactac
    94981 aatggaatct ctcaattttc atctgttcga aatcgttcat caagctctac tttagataaa
    95041 cttggtttta aatcctctgg gactaatctc aatctccgat atgcaaataa tagtattttg
    95101 gctgatagtt tatttggtat ccagtacaat atctcagaca gtcctattga taagtatggc
    95161 tttaaagata tctatcaaaa agataatctt accctatatg aaaatcaata ctctcttccg
    95221 attgcagttg ctagtcaatc tgtttacaat gatgtcaagt tcaatgaaca taccttggat
    95281 aatcaggcct catttttaaa tcaacttgct aacgtcaatt ttgattattt ttctccaata
    95341 ccttatgaaa aaacagaaaa aatagaaaat actaatgatt tgattagtgt cacaagttct
    95401 tcaaatgaag atgcagcaat ccagtatcaa attgaagttc cagaaaacag ccaagtttat
    95461 ctctctttca taaaccttca cttttctaac gataaacaaa agaaggttga catacttgta
    95521 aatggtgaaa aaaagacttt tacaactgat aatgtcttct ccttctttaa tctaggatat
    95581 actaaagaga aaaaaacttt caatatcaat gttagtttcc ctggaaattc acaagtatca
    95641 tttgaatctc ctaccttcta tcgtttagat accaaaactt tcaccgaggc aattcaaaaa
    95701 attaaagaac aacctgtcac agtatcaact tctaaaaaca aggtttttgc tacatatgat
    95761 gtccaacaag atacatctat tttcttcacc attccttatg acaaaggttg gtctgcctac
    95821 caagatggta agaaaataga aattaaacaa gctcaaactg gatttatgaa agttgacatt
    95881 cccaagggga aaggaactat tacactttcc ttcattccca atggttttat tactggagca
    95941 atctgttcct ttacttctct cttactattt ggaatctata atcacagacg aaagtcatct
    96001 aaggcataaa aaatcgacca gttaatcggt cgattttttt aatcttcttc cattttctta
    96061 tgttgatagg ctagcatacc taaaccagta aatagagcta gtatgacagc taggaaaatg
    96121 acttgttgat agagattgtt tgtcgtaatc ccgaaactga atagctcatt ggtaaccagg
    96181 gattaataga tctaaagaaa tcatttgtca aagcaagtgg ataagtacct gcacttgatg
    96241 ctaactgtag taaaagcaaa ataagtgaga aaaaagctcc tatacggcta ttccacgttg
    96301 ctaaagtggt caccatagac atgaatacta aacttgttag gatgatgaga ataaatattc
    96361 tcatctcatg attagcagtt aaaccaataa gctgaactcc tccatatacc aaaattcctg
    96421 ccaaaacagc tataatacca tttatttcag ctcaagattt caaccaagcc caacggctct
    96481 ctggatgacg tcctgaaggc aatttcgcaa atatcatatt tgttgatatt gctgcaaaaa
    96541 aaagagcaac tgatatcata taaggagcta ttgcgattcc atttacagga acttgatcat
    96601 tgtctgtttt tgaaagattg agtggatttg acaaaatctc tgcattttta gattctgttg
    96661 atactgattt gagttgatca ctagcattac ctagtccttg tcctaaagaa gcaagtcctg
    96721 tctgtaaatc ttccaatcca gaagttaact ttgttccacc ttctgctagt ttcccagatc
    96781 catctgccaa tttattagct ctattctcta atggagaagc acctgaaagt aactgactgg
    96841 atttgtctgc taattgccca gatcctgatt gtaattaacc aactcctgct gtcaatctag
    96901 aagatttttg tgtcaaggtg tttgagcctg aaactagttt atccaaacta cctgtcaagg
    96961 tggcattttt ttcacttagt tgacttgcgc cctgagaaac tttatcaaca cctgtagtat
    97021 atgcgtttac acctgatgca atcaactgac tggcaggaac taatttgcta gtaacagctc
    97081 cttgtatctc tgttaatcca cttgacaatc ctatcaaaga agtagaagta ataggtaata
    97141 cttgattagc ttgatttttt aaagtcgaaa gattagaaga ttgattttgt aagttttcta
    97201 aacttccctg taaaccttgt actaaagcta caattgactg agccgattga atactatcag
    97261 ttgaattttg agatacagaa tcacttatcc cagtttgttg ctcacttgtc aatgattgat
    97321 aagctgctgt cgattgaata ttggataatg tagttgtttt tttagataaa tcacttggta
    97381 aagtcactac catatagtaa tcgccatctt ccaatccctt ctttccttcc tcttcatcta
    97441 caaaatgaaa atccaaggtt ttattttctt ttaaattgga caccatgtct tttcctattg
    97501 ccatagtatt accattatag gaagcctctt tatcattatt tacaactgcc acaggtaagt
    97561 cagacaattg cccatatgga tcccacattg atgacaaaaa tatgatattg tacagagctg
    97621 gaataagaga aatcccgatc atgacaataa taaaggttgt tttttttaaa ttgctttcca
    97681 ttctttaaac atagtttctc cttttttaaa catattgtct aaaattttga tataatagat
    97741 tatacattaa aaaatctaaa ttacaagata aaaaatctat ttttagacat atagtctaat
    97801 ttgtttacaa ggaggaaata tgcaagaaag taacaaacgc ttaaaaacaa agcgaactat
    97861 tgaaaatgct atggtacaat tactgatgga acagccattt gataaaattt ctactgtcaa
    97921 attagtagaa aaagccggaa ttagtcgttc cagcttctat actcactata aggataagta
    97981 tgatatgatt gagcactatc aaagcaagct attccataca tttgaatata tttttcaaaa
    98041 acatgctcat cacaaaagag acgctatttt agaagttttt gaatatctag agtcagaacc
    98101 acttctggct gcccttcttt ctgaaaatgg gactaaagaa atccaaaatt tcttacgaaa
    98161 taaacttcat atcatgctta gtacagattt acaaaagcga tttatgcaac tgaatctaaa
    98221 taccactgaa ttagaatata gtagcatcta tctaactcat gcactttttg gtgtctgcca
    98281 aacttggatt gcacatggaa aaaaagaaag ttctcaagaa ataacagact tccttatgaa
    98341 aatgcttggt gatacaaatt gatacaaaaa gaggaacaca gctgtgttcc cttttatcta
    98401 tactccgcca gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca
    98461 actgagctat ggcggataaa atagtccgta cgggattcga acccgtgtta ccgccgtgaa
    98521 aaggcggtgt cttaacccct tgaccaacgg accttctatc tgtagcagat ataaccatta
    98581 tatcaatttc ttgctaattg tcaatcactt ttgagatttt ttctctaaaa tatcttttaa
    98641 ttttctaatt tttaatcttg aaataggaca acgatggtct tcatagaaaa caatttctaa
    98701 gttttttcga tcaatttctc tgatattgcc tatatttacc aaaaatgact tgtgaggaga
    98761 ataaaatcgc tgagtatgtt tgtccttttc ctgaatatct gtcatggtac cataaaactc
    98821 ttttgcaaaa ttcttaccaa taatgcgcaa tttatgagat acccctgttg tttcaatata
    98881 caaaatatca tggtaaggaa tttttaaatc atttcccttg taattgtagt cgaaataatc
    98941 tacaacatct tcattttcaa gtaacatact cttcgtgtag aagatatttt gctcaattct
    99001 cttcttaaac atctcatcat tgatatcctt atcaacaaaa tctagggctg atacctggta
    99061 tttataggtt agagtcgcaa actctgatcg actagtgata aagacgataa tagcgtaagg
    99121 attgtaatga cgaatgagct gagccacttc aaatcccttt ttctcaattc catgaatatc
    99181 gatatctagg aaataaagct gatttacttc atcattttca atgtattctt caaattcacg
    99241 gacttttccc gttgtcttgt atgatattgg aatattcgat tctttcgaaa tttcatccaa
    99301 tattctctct agtctcactt gatgttcaat aacatcttct aaaattaaaa ctttcattca
    99361 aattccctct taaatctaat gatttgtcta aatgtactgc cttccatctc tgtttctaaa
    99421 ataatattgt tgtacttatc tagtagttct ttcacattat ttaatccgac tccgcgattt
    99481 cttcccttag tggagaatcc taaggcaaat agatctcctg aaggagtcat cgtcatttta
    99541 catgaattct gaatcacaat aactgtttca gtttccatct taataactgc tacttccatc
    99601 tgctttttat agctatcagc cgatccttcg acagcattat tcaataaaac gctcatgata
    99661 cgaaccaaat ccaatagttc aattggaagc ttggtaatcg tatcttttac ttccagtgta
    99721 aactctacac cattatttcg agcatagaca attgactgag caaccaaact tcgtaaagct
    99781 gagtcttcta tgttgttcaa atcaaagtaa gtgtacttat ctgaacgcaa tttatgattt
    99841 gctttgacta aaacttcatt gtaaattctg tcaatttcct gtaaattacc actgtcaatt
    99901 gccatctgca tgctgacaag cattccagca taatcatgtc gaaaaccacg gatttcatta
    99961 tacagaccaa caatttcatc tgtgtaattc tgtaaatgtt tctgttcaaa tttcttctgc
   100021 ttcaaagcaa tctctttctc catttgaact ttatgagaat tcattgcaaa gaaggtcaaa
   100081 aggagagaga taaagacaat agatgacaaa atacttccaa aactattcaa atgtttaatc
   100141 gtacttacca tatctgaaac gaaagataca atatgtagca atagtaaagc aaaaaatact
   100201 tttttcaaga aaggataaag gtagtcctcg tcaaaatagg ctagttccaa atggaaatag
   100261 taaatgattt ttaatgtaac aaaataggtt aacaccgtca caacgaaaaa gaatgggaaa
   100321 tgatattgta aaacaaaatt atctcctgtt atagaggaga aagttacgga cagaaagtta
   100381 tgagtgctct catataaaag agatagtagt aaacttagga atagtcctct atccctctca
   100441 tactgtttca tccatcgaaa ataggaatat aatcccaaag gaaataaaaa tctttcaatc
   100501 cctaacccat ctaaatatag aatatataag ggaaaatcaa atactatttc tgttagtaat
   100561 gtataagcac caaaaacgaa taattctttt ctatttattt gacctttaca aataaaatgg
   100621 taactgtgac taataattaa aaaatgaaca ataaccgtcc caaatccaaa taaatccatt
   100681 actctttccc cttatttcat tacttttttc tttgtaaaat aaaatcacgg aagaattttg
   100741 acaacctcat ctccccacct ttaatctttt gtaagtcttt ttccttcaaa gctacaaact
   100801 gttccaattt aactgtgttt ttcataataa aatctcctaa aatgtttttt cttgtaagct
   100861 aacttacaaa aaccattata caaaatggaa tttcgtttta gataaaattc tctcaactgt
   100921 catttttttc tcccaaagtg tactttttta agaaaaaagc cgggaaaatt cccagctttg
   100981 ctattatatt gatcccagca ggattcgaac ctgcgaccgt tcgcttagaa ggcgaatgct
   101041 ctatccagct gagctatgag acctaataca attattctac caaaaattca attaaaagtc
   101101 aattttctat ttatggtagg ggaatccctg ctgaatcgta aaagcgcgat agatttgttc
   101161 aacaagaact agtctcatta actgatgggg taaggttagg cgaccaaaac tgacagaaag
   101221 attggctcta ttttttacag atgatgacaa tcctaaactt cccccaataa taaaagtaag
   101281 agtagaaaat ccttttatag aagtttcttc taactgctta ctaaattctt ctgagaagaa
   101341 agttttccct tcaatggcta acacaataac gaaatcacgg tcagcaattt ttgataaaat
   101401 tctctgacct tctatttcta aaatcttttg attttctgat tcactggcct tatctggtgt
   101461 tttttcatct gataactcaa tcatttcaaa cttagcaaat ctagaaattc gttttgaata
   101521 ctctgcgata ccatctttta aatacttttc tttcagtttc ccaactgtta caactttaat
   101581 tttcatgact ctattctaac atattctcta ttttttcaca tcttattcac aaaataaaaa
   101641 atagatttca attaagaaaa tcacagtttc aaaagagtta tccacagttt gtgtaaaact
   101701 tttgtgttta agttataatt aagctagtca gtttatactt tcagtaattc aaacatatgg
   101761 aggcaaatat gaaacatcta aaaacatttt acaaaaaatg gtttcaatta ttagtcgtta
   101821 tcgtcattag cttttttagt ggagccttgg gtagtttttc aataactcaa ctaactcaaa
   101881 aaagtagtgt aaacaactct aacaacaata gtactattac acaaactgcc tataagaacg
   101941 aaaattcaac aacacaggct gttaacaaag taaaagatgc tgttgtttct gttattactt
   102001 attcggcaaa cagacaaaat agcgtatttg gcaatgatga tactgacaca gattctcagc
   102061 gaatctctag tgaaggatct ggagttattt ataaaaagaa tgataaagaa gcttacatcg
   102121 tcaccaacaa tcacgttata aatggcgcca gcaaagtaga tattagattg tcagatggga
   102181 ctaaagtacc tggagaaatt gtcggagctg acactttctc tgatattgct gtcgtcaaaa
   102241 tctcttcaga aaaagtgaca acagtagctg agtttggtga ttctagtaag ttaactgtag
   102301 gagaaactgc tattgccatc ggtagcccgt taggttctga atatgcaaat actgtcactc
   102361 aaggtatcgt atccagtctc aatagaaatg tatccttaag atcggaagat ggacaagcta
   102421 tttctacaaa agccatccaa actgatactg ctattaaccc aggtaactct ggcggcccac
   102481 tgatcaatat tcaagggcag gttatcggaa ttacctcaag taaaattgct acaaatggag
   102541 gaacatctgt agaaggtctt ggtttcgcaa ttcctgcaaa tgatgctatc aatattattg
   102601 aacagttaga aaaaaacgga aaagtgacgc gtccagcttt gggaatccag atggttaatt
   102661 tatctaatgt gagtacaagc gacatcagaa gactcaatat tccaagtaat gttacatctg
   102721 gtgtagttgt tcgttcggta caaagtaata tgcctgccaa tggtcacctt gaaaaatacg
   102781 atgtaattac aaaagtagat gacaaagaga ttgcttcatc aacagactta caaagtgctc
   102841 tttacaacca ttctatcgga gacaccatta agataaccta ctatcgtaac gggaaagaag
   102901 aaactacctc tatcaaactt aacaagagtt caggtgattt agaatcttga ttgacatcta
   102961 tgtaaagaaa gctttacata agagaaaaga tgtgttagtg tagaatcatg gaaaaatttg
   103021 aaatgatttc tatcacagat atacaaaaaa atccctatca accccgaaaa gaatttgata
   103081 gagaaaaact agatgaacta gcacagtcta tcaaagaaaa tggggtcatt caaccgatta
   103141 ttgttcgtca atctcctgtt attggttatg aaatccttgc aggagagaga cgctatcggg
   103201 cttcactttt agctggtcta cggtctatcc cagctgttgt taaacagatt tcagaccaag
   103261 agatgatggt ccagtccatt attgaaaatt tacagagaga aaatttaaac ccaatagaag
   103321 aagcactcgc ctatgaatct ctcgtagaga aaggattcac ccatgctgaa attgcagata
   103381 agatgggcaa gtctcgtcca tatatcagca actccattcg tttactttcc ttgccagaac
   103441 agattctttc agaagtagaa aatggcaaac tatcacaagc ccatgcgcgt tccctagttg
   103501 ggttaaataa ggaacaacaa gactatttct ttcaacggat tatagaagaa gatatttctg
   103561 taaggaaatt agaagctctt ctgacagaga aaaaacaaaa gaaacagcaa aaaactaatc
   103621 atttcataca aaatgaagaa aaacagttaa gaaaactact cggattagat gtagaaatta
   103681 aactatctaa aaaagacagt ggaaaaatca ttatttcttt ttcaaatcaa gaagaatata
   103741 gtagaattat caacagcctg aaataaggct gttcttttat ttttttatct cacaaggtta
   103801 tccactatgt ttttcgataa aaagcttaat aaatcaataa tttcttcttt tatccccaac
   103861 ctgtggataa agtttggtaa cattgtggat tatttttcac agcttgtgga aaattcttgc
   103921 tatctatggt aaaatatctc tagtattaaa cttttaaata gtaaaggagg agaaaggatt
   103981 gaaagaaaaa caattttgga atcgtatatt agaatttgca caagaaagac tgactcgatc
   104041 catgtatgat ttctatgcta ttcaagctga actcatcaag gtagaggaaa atgttgccac
   104101 tatatttcta cctcgctctg aaatggaaat ggtctgggaa aaacaactaa aagatattat
   104161 tgtagtagct ggttttgaaa tttatgacgc tgaaataact ccccactata ttttcaccaa
   104221 acctcaagat acgactagct cacaagttga agaagctaca aatttaactc tttataacta
   104281 tagtccaaag ttagtatcta ttccttattc agatacggga ttaaaagaaa agtatacctt
   104341 tgataacttt attcaagggg atggaaatgt ttgggctgta tcagccgctt tagctgtctc
   104401 tgaagatttg gctctgacct ataaccctct ttttatctat ggaggaccag gccttggtaa
   104461 gactcactta ttaaacgcta ttggaaatga aattctaaaa aatattccta atgcgcgtgt
   104521 taaatatatc cctgccgaaa gctttattaa tgactttctt gatcacctaa gacttgggga
   104581 aatggaaaag tttaaaaaga cctatcgtag tcttgatctt ttgttaatcg atgatattca
   104641 gtcactcagc ggaaaaaaag ttgcaactca ggaagaattt ttcaatacct ttaacgccct
   104701 tcatgacaag caaaaacaga ttgtcctaac gagtgatcgt agtccaaaac atctagaagg
   104761 gctcgaggag aggcttgtca cgcgttttag ttggggattg acacaaacta tcacaccccc
   104821 tgactttgaa acacgtattg ccattttaca aagtaaaacg gaacatttag gctacaattt
   104881 ccaaagtgat actctagaat acctagctgg gcaatttgat tcaaatgttc gagatcttga
   104941 gggagccatc aacgacatca ctttaattgc cagagtaaaa aaaatcaagg atatcactat
   105001 tgatattgct gcagaagcca ttagagcccg caaacaagat gttagccaaa tgctcgtcat
   105061 cccaattgat aaaatccaaa ctgaagttgg taacttttat ggtgttagta tcaaagaaat
   105121 gaagggaagt agacgccttc aaaatattgt tttggcccgt caagtagcca tgtatttatc
   105181 tagagaacta acagataata gtcttccaaa aattgggaag gaatttgggg gaaaagatca
   105241 taccacagtc attcatgccc atgccaaaat aaaatctttg attgatcaag acgataattt
   105301 acgtttagaa attgaatcaa tcaaaaagaa aatcaaataa tttgtggata acttttagtt
   105361 ttttatcttt tttatccaca ttttttaaac aagctaaaaa acttgatatg acttgtttaa
   105421 aggctgtttt ccacagattt cacagactct attattacta ttatctttct aatactaaaa
   105481 ataaataaag gagaatccat gattcatttt tcaattaata aaaatttatt tctacaagca
   105541 ttaaatacta ctaagagagc tattagttct aaaaatgcca ttcctatttt atcaacagta
   105601 aaaattgacg tgaccaatga aggtattact ttaattggtt caaatggtca aatttcaatt
   105661 gaaaatttta tttctcaaaa aaatgaagat gctggtttgt taattacttc tttaggttcg
   105721 atccttcttg aagcttcttt ctttatcaat gtagtatcta gtttacctga tgtaactctt
   105781 gattttaaag aaattgaaca aaatcaaatt gttttaacca gtggcaaatc agaaattacc
   105841 ctaaaaggaa aagatagcga acaatatcca cgaatccaag aaatttcagc aagcactcct
   105901 ttaatacttg aaacaaaatt actcaagaaa attattaatg aaacagcctt tgctgcaagt
   105961 acacaagaga gtcgtccgat tttaacaggt gtccacttcg tattgagtca acacaaagag
   106021 ttaaaaacag ttgcaacaga ctctcatcgc ctaagccaga aaaaattgac tcttgaaaaa
   106081 aatagtgatg attttgatgt cgtaattcct agccgttctc tacgcgaatt ttcagcggta
   106141 tttacagatg atatcgaaac tgtagagatt ttctttgcca ataaccaaat cctctttaga
   106201 agcgaaaata ttagcttcta tactcgtctc ctagaaggaa actatcctga tacagatcgc
   106261 ttgattccaa cagactttaa cattactatt acttttaatg tggtaaactt acgccagtca
   106321 atggagcgtg cccgtctttt atcaagtgcg actcaaaatg gtactgtgaa acttgaaatt
   106381 aaggatgggg ttgttagcgc ccatgttcac tctccagaag ttggtaaagt aaacgaagaa
   106441 atcgatactg atcaggttac tggtgaagat ttgaccatta gtttcaaccc aacttacttg
   106501 attgattctc ttaaagcttt aaatagcgaa aaggtgacca ttagctttat ctcagctgtt
   106561 cgtccattta ctcttgtgcc agcagatact gacgaagact tcatgcagct aattacacca
   106621 gttcgtacaa attaagtgaa agaggttgag cctggctcgc ctcttttatg atataatcga
   106681 aaaagaaaag gagagtagta tgtatcaagt tggaaatttt gttgagatga aaaaatcaca
   106741 cgcttgtaca atcaagtcaa ctggtaaaaa ggctaatcgt tgggaaatta cacgtgtagg
   106801 agcagatatc aaaataaaat gcagtaattg tgagcatgtt gtcatgatgg ggcgatatga
   106861 ttttgagcga aaaatgaata aaattattga ctgagaaccc ttagttagag ggttagcact
   106921 ttatcccttt ttgtgttata atattaggga ttgaaatgaa aacggagaat gagaaatatg
   106981 gctttgacag caggtatcgt tggtttgcca aacgttggta aatcaacact atttaatgca
   107041 attacaaaag caggagcaga ggcagcaaac tacccatttg cgactattga tccaaatgtt
   107101 ggaatggtgg aagttccaga tgaacgccta caaaaactaa ctgaaatgat aactcctaaa
   107161 aagacagttc ccacaacatt tgaatttacg gatattgcag ggattgtaaa aggagcttca
   107221 aaaggagaag ggctagggaa taaattcttg gccaatattc gtgaagtaga tgcgattgtt
   107281 cacgtagttc gtgcttttga tgatgaaaat gtgatgcgcg agcaaggacg tgaagacgcc
   107341 tttgtagatc cacttgcaga tattgataca attaatctgg aattaattct tgctgactta
   107401 gaatcagtga acaaacgata tgcgcgtgta gaaaagatgg cacgtacgca aaaagataaa
   107461 gaatcagtag cagaattcaa tgttcttcaa aagattaaac cagtcctaga agacgggaaa
   107521 tcagctcgta ccattgaatt tacagatgag gaacaaaagg ttgtcaaagg tcttttcctt
   107581 ttgacgacta aaccagttct ttatgtagct aatgtggacg aggatgtggt ttcagaacct
   107641 gactctatcg actatgtcaa acaaattcgt gaatttgcag cgacagaaaa tgctgaagta
   107701 gtcgttattt ctgcgcgtgc tgaggaagaa atttctgaat tggatgatga agataaaaaa
   107761 gagtttcttg aagccattgg tttgacagaa tcaggtgtag ataagttgac gcgtgcatct
   107821 taccacttgc ttggattggg aacttacttc acagctggtg aaaaagaagt tcgcgcttgg
   107881 actttcaaac gtggtatgaa ggctactcaa gcagctggta ttatccactc agactttgaa
   107941 aaaggcttta ttcgtgcagt aaccatgtca tatgaagatc tagtgaaata cggatctgaa
   108001 aaggccgtaa aagaagctgg acgcttgcgt gaagaaggaa aagaatatat cgttcaagat
   108061 ggcgatatca tggaattccg ctttaatgtc taaaaattaa taaatggtgt caattaggtt
   108121 ggaaaaaaat tccaaccctt ttggcttttg aaaggaaaaa taaatgacca aattacttgt
   108181 aggcttggga aatccagggg ataaatattt tgaaacaaaa cacaatgttg gttttatgtt
   108241 gattgatcaa ctagcgaaga aacagaatgt cacttttaca cacgataaga tatttcaagc
   108301 tgacctagca tcctttttcc taaatggaga aaaaatttat ctggttaaac caacgacctt
   108361 tatgaatgaa agtggaaaag cagttcatgc tttattaact tactatggtt tggatattga
   108421 cgatttactt atcatttacg atgatcttga catggaagtt gggaaaattc gtttaagagc
   108481 aaaaggctca gcaggtggtc ataatggtat caagtctatt attcaacata taggaactca
   108541 ggtctttaac cgtgttaaga ttggaattgg aagacctaaa aatggtatgt cagttgttca
   108601 tcatgttttg agtaagtttg acagggatga ttatatcggt attttacagt ctgttgacaa
   108661 agttgacgat tctgtaaact actatttaca agagaaaaat tttgagaaaa caatgcagag
   108721 gtataacgga taaatggtga ccttattaga tttattctca gaaaatgatc agattaaaaa
   108781 atggcatcaa aatttaacag ataagaaaag acaactaata cttggtttat caacatctac
   108841 taaggcgctt gcaattgcaa gcagtttaga aaaagaagat aggattgtgt tattgacgtc
   108901 aacttatgga gaagcagaag gacttgttag tgatcttata tctatcttgg gtgaggaact
   108961 cgtctatcca tttttggtag atgatgctcc tatggtggag tttttgatgt cttcacagga
   109021 aaaaattatt tcacgggttg aagccttgcg ttttttgact gattcatcta agaaagggat
   109081 tttagtttgt aatatcgcag caagtcgatt gattttaccg tctcccaatg cattcaaaga
   109141 tagtattgta aaaatctcag ttggtgaaga atatgatcaa cacgcgttta tccatcagtt
   109201 aaaggaaaat ggctatcgaa aagttactca agtacaaact cagggcgaat ttagtcttcg
   109261 aggagatatt ttagatattt ttgaaatatc ccagttagaa ccttgtcgaa ttgagttttt
   109321 tggtgatgaa attgatggta tcaggtcatt tgaagtagaa acacaattat cgaaagaaaa
   109381 taagacagaa ctcactatct ttccagctag tgatatgctt ttgagagaaa aggattatca
   109441 acgaggacag tcagctttag aaaaacaaat ttcaaaaact ttatcaccta ttttgaaatc
   109501 atacctagaa gaaattcttt caagttttca tcaaaagcaa agtcatgcag attctcggaa
   109561 gtttttatct ttgtgctatg ataagacatg gactgtcttt gattatattg aaaaagatac
   109621 tccaatattc tttgatgatt atcaaaaatt gatgaatcag tatgaagtat ttgaaagaga
   109681 attagcgcag tactttacag aagaattaca gaatagtaaa gcattttctg atatgcagta
   109741 tttttctgat attgaacaaa tctataaaaa acaaagtcca gtgacctttt tctctaatct
   109801 tcaaaagggt ttaggaaatc tcaaatttga caaaatttat caattcaatc aatatcctat
   109861 gcaggaattt ttcaatcagt tttcttttct aaaagaagaa attgaacgat ataaaaaaat
   109921 ggattacacc attattctgc agtctagcaa ttcaatggga agtaaaacat tggaggatat
   109981 gttagaggaa tatcagatta aattggattc tagagataag acaagtatct gtaaagaatc
   110041 tgtaaactta atagagggta atctcagaca tggttttcat tttgtagatg aaaagatttt
   110101 attgataact gaacatgaga tttttcaaaa gaaattaaag cgtcgttttc gaagacaaca
   110161 tgtttcaaat gcagagagat taaaagatta caatgaactt gaaaaagggg actatgttgt
   110221 ccatcatatc catgggattg gtcaatatct aggaattgaa accattgaaa tcaagggaat
   110281 tcatcgcgat tatgtcagtg tccaatacca aaatggtgat caaatttcta ttcccgtgga
   110341 acagattcat ctactgtcca aatatatttc aagtgatggt aaagttccaa aactcaataa
   110401 attaaatgat ggtcatttta aaaaggccaa gcaaaaggtt aagaaccagg tagaggatat
   110461 agctgatgat ttaatcaaac tctactctga acgtagtcag ttgaagggtt ttgctttctc
   110521 agctgatgat gatgatcaag atgcctttga tgatgctttc ccttatgttg aaacggatga
   110581 tcaacttcgt agtattgagg aaatcaagag ggatatgcag gcttctcacc caatggatcg
   110641 acttttagtt ggggatgttg gttttggaaa gactgaagtt gctatgcgtg cagcctttaa
   110701 agcagtcaat gatcacaaac aggttgtcat tctagttccg acgacggttt tagcgcaaca
   110761 gcactatacg aattttaagg aacgattcca aaattttgca gttaatgttg atgtgttgag
   110821 tcgctttaga agtaaaaaag agcagactgc aacacttgaa aaattgaaaa acggtcaagt
   110881 cgatattttg attggaacac atcgtgtttt gtcaaaagat gttgtgtttg ctgatttggg
   110941 cttgatgatt attgatgagg aacagcgatt tggtgtcaag cataaggaaa ctttgaaaga
   111001 actgaagaaa caagtggatg tcctaacctt gaccgctacg ccaatccctc gtaccctcca
   111061 tatgtctatg ctgggaatca gagatttgtc tgttattgaa actccgccga ctaatcgcta
   111121 tcctgttcag acctatgttt tggaaaagaa tgatagtgtc attcgtgatg ctgtcttgcg
   111181 tgaaatggag cgtggaggtc aagtttacta tctttacaac aaagttgaca caattgttca
   111241 gaaggtttca gaattacagg agttgattcc ggaggcttcg attggatatg ttcatggtcg
   111301 aatgagtgaa gtccagttgg aaaatactct attagacttt attgagggac aatacgatat
   111361 cttggtgacg actactatta ttgagacagg ggtggacatt ccaaatgcta atactttatt
   111421 tattgaaaat gcggaccata tgggcttgtc aaccttatat cagttaagag gaagagtcgg
   111481 tcgtagtaat cgtattgctt atgcttatct catgtatcgt ccagaaaaat caatcagtga
   111541 agtctctgaa aagagattag aagcgattaa aggatttaca gaattgggct ctggctttaa
   111601 gattgcaatg cgagatcttt cgattcgtgg agcaggaaat cttttaggaa aatcccagtc
   111661 tggtttcatt gattctgttg gttttgaatt gtattcgcag ttattagagg aagctattgc
   111721 taaacgaaac ggtaatgcta acgctaacac aagaaccaaa gggaatgctg agttgatttt
   111781 gcaaattgat gcctatcttc ctgatactta tatttctgat caacgacata agattgaaat
   111841 ttacaagaaa attcgtcaaa ttgacaaccg tgtcaattat gaagagttac aagaggagtt
   111901 gatagaccgt tttggagaat acccagatgt agtagcctat ctgttagaga ttggtttggt
   111961 caaatcatgc ttggacaagg tctttgttca acgtgtggaa agaaaagata ataaaattac
   112021 aattcaattt gaaaaagtca ctcaacgact gtttttagct caagattatt ttaaagcttt
   112081 atccgtaacg aacttaaaag caggcatcgt tgagaataag ggattaatgg agcttgtatt
   112141 tgatgtccaa aataagaaag attatgaaat tttagaaggt ttgctgattt ttggagaaag
   112201 tttattagag ataaaagagt ctaaggaaga aaattccatt tgatattttt cttctataaa
   112261 atagataaaa atggtacaat aataaattga ggtaataagg atgagattag ataaatattt
   112321 aaaagtatcg cgaattatca agcgtcgtac agtcgcaaag gaagtagcag ataaaggtag
   112381 aatcaaggtt aatggaatct tggccaaaag ttcaacggac ttgaaagtta atgaccaagt
   112441 tgaaattcgc tttggcaata agttgctgct tgtaaaagta ctagagatga aagatagtac
   112501 aaaaaaagaa gatgcagcag gcatgtatga aattatcagt gaaacacggg tagaagaaaa
   112561 tgtctaaaaa tattgtacaa ttgaataatt cttttattca aaatgaatac caacgtcgtc
   112621 gctacctgat gaaagaacga caaaaacgga atcgttttat ggggggggta ttgattttga
   112681 ttatgctatt atttatcttg ccaactttta atttagcgca gagttatcag caattactcc
   112741 aaagacgtca gcaattagca gacttgcaaa ctcagtatca aactttgagt gatgaaaagg
   112801 ataaggaaac agcatttgct accaagttga aagatgaaga ttatgctgct aaatatacac
   112861 gagcgaagta ctattattct aagtcgaggg aaaaagttta tacgattcct gacttgcttc
   112921 aaaggtgata aaatggaaaa tttattagac gtaatagagc aatttttgag tttgtcagat
   112981 gaaaagctgg aagaattggc tgataaaaat caattattgc gtttacaaga agaaaaggaa
   113041 aggaagaatg cgtaaattct taattatttt gttgctacca agttttttga ccatttcaaa
   113101 agtcgttagc acagaaaaag aagtcgtcta tacttcgaaa gaaatttatt acctttcaca
   113161 atctgacttt ggtatttatt ttagagaaaa attaagttct cccatggttt atggagaggt
   113221 tcctgtttat gcgaatgaag atttagtagt ggaatctggg aaattgactc ccaaaataag
   113281 ttttcaaata accgagtggc gcttaaataa acaaggaatt ccagtattta agctatcaaa
   113341 tcatcaattt atagctgcgg acaaacgatt tttatatgat caatcagagg taactccaac
   113401 aataaaaaaa gtatggttag aatctgactt taaactgtac aatagtcctt atgatttaaa
   113461 agaagtgaaa tcatccttat cagcttattc gcaagtatca atcgacaaga ccatgtttgt
   113521 agaaggaaga gaatttctac atattgatca ggctggatgg gtagctaaag aatcaacttc
   113581 tgaagaagat aatcggatga gtaaagttca agaaatgtta tctgaaaaat atcagaaaga
   113641 ttctttctct atttatgtta agcaactgac tactggaaaa gaagctggta tcaatcaaga
   113701 tgaaaagatg tatgcagcca gcgttttgaa actctcctat ctctattata cgcaagaaaa
   113761 aataaatgag ggtctttatc agttagatac gactgtaaaa tacgtatctg cagtcaatga
   113821 ttttccaggt tcttataaac cagagggaag tggtagtctt cctaaaaaag aagataataa
   113881 agaatattct ttaaaggatt taattacgaa agtatcaaaa gaatctgata atgtagctca
   113941 taatctattg ggatattaca tttcaaacca atctgatgcc acattcaaat ccaagatgtc
   114001 tgccattatg ggagatgatt gggatccaaa agaaaaattg atttcttcta agatggccgg
   114061 gaagtttatg gaagctattt ataatcaaaa tggatttgtg ctagagtctt tgactaaaac
   114121 agattttgat agtcagcgaa ttgccaaagg tgtttctgtt aaagtagctc ataaaattgg
   114181 agatgcggat gaatttaagc atgatacggg tgttgtctat gcagattctc catttattct
   114241 ttctattttc actaagaatt ctgattatga tacgatttct aagatagcca aggatgttta
   114301 tgaggttcta aaatgaggga accagatttt ttaaatcatt ttctcaagaa gggatatttc
   114361 aaaaagcatg ctaaggcggt tctagctctt tctggtggat tagattccat gtttctattt
   114421 aaggtattgt ctacttatca aaaagagtta gagattgaat tgattctagc tcatgtgaat
   114481 cataagcaga gaattgaatc agattgggaa gaaaaggaat taaggaagtt ggctgctgaa
   114541 gcagagcttc ctatttatat cagcaatttt tcaggagaat tttcagaagc gcgtgcacga
   114601 aattttcgtt atgatttttt tcaagaggtc atgaaaaaga caggtgcgac agctttagtc
   114661 actgcccacc atgctgatga tcaggtggaa acgattttga tgcgcttgat tcgaggaact
   114721 cgcttgcgct atctatcagg aattaaggag aagcaagtag tcggagagat agaaatcatt
   114781 cgtcccttct tgcattttaa gaaaaaagac tttccatcaa tttttcactt tgaagataca
   114841 tcaaatcagg agaatcatta ttttcgaaat cgtattcgaa attcttactt accagaattg
   114901 gaaaaagaaa atcctcgatt taggaatgca atcttaggca ttagcaatga aattttagat
   114961 tatgatttgg caatagctga attatctaac aatattaatg tggaagattt acagcagtta
   115021 ttttcttatt ctgagtctac acaaagagtt ttacttcaaa cttatctgaa tcgttttcca
   115081 gatttgaatc ttacaaaagc tcagtttgct gaagttcagc agattttaaa atctaaaagc
   115141 cagtatcgtc atccgattaa aaatggctat gaattgataa aagagtacca acagtttcag
   115201 atttgtaaaa tcagtccgca ggctgatgaa gaggaagatg aacttgtgtt acactatcaa
   115261 aatcaggtag cttatcaagg atatttattt tcctttggac ttccattaga aggtgaatca
   115321 attcaacaaa tacctgtttc acgtgaaaca tccatacaca ttcgtcatcg aaaaacagga
   115381 gatgttttga ttcaaaatgg gcatagaaaa aaactcagac gtttatttat tgatttgaaa
   115441 atccctatgg aaaagagaaa ctctgctctt attattgagc aatttggtga aattgtctca
   115501 attttgggaa ttgcgaccaa taatttgagt aaaaaaacga aaaatgatat aatgaacact
   115561 gtactttata tagaaaaaat agataggtaa aaaatgttag aaaacgatat taaaaaagtc
   115621 ctcgtttcac acgatgaaat tacagaagca gctaaaaaac taggtgctca attaactaaa
   115681 gactatgcag gaaaaaatcc aatcttagtt gggattttaa aaggatctat tccttttatg
   115741 gctgaattgg tcaaacatat tgatacacat attgaaatgg acttcatgat ggtttctagc
   115801 taccatggtg gaacagcaag tagtggtgtt atcaatatta aacaagatgt gactcaagat
   115861 atcaaaggaa gacatgttct atttgtagaa gatatcattg atacaggtca aactttgaag
   115921 aatttgcgag atatgtttaa agaaagagaa gcagcttctg ttaaaattgc aaccttgttg
   115981 gataaaccag aaggacgtgt tgtagaaatt gaggcagact atacctgctt tactatccca
   116041 aatgagtttg tagtaggtta tggtttagac tacaaagaaa attatcgtaa tcttccttat
   116101 attggagtat tgaaagagga agtgtattca aattagaaag aataatcttt aatgaaaaaa
   116161 caaaataatg gtttaattaa aaatcctttt ctatggttat tatttatctt tttccttgtg
   116221 acaggattcc agtatttcta ttctgggaat aactcaggag gaagtcagca aatcaactat
   116281 actgagttgg tacaagaaat taccgatggt aatgtaaaag aattaactta ccaaccaaat
   116341 ggtagtgtta tcgaagtttc tggtgtctat aaaaatccta aaacaagtaa agaaggaaca
   116401 ggtattcagt ttttcacgcc atctgttact aaggtagaga aatttaccag cactattctt
   116461 cctgcagata ctaccgtatc agaattgcaa aaacttgcta ctgaccataa agcagaagta
   116521 actgttaagc atgaaagttc aagtggtata tggattaatc tactcgtatc cattgtgcca
   116581 tttggaattc tattcttctt cctattctct atgatgggaa atatgggagg aggcaatggc
   116641 cgtaatccaa tgagttttgg acgtagtaag gctaaagcag caaataaaga agatattaaa
   116701 gtaagatttt cagatgttgc tggagctgag gaagaaaaac aagaactagt tgaagttgtt
   116761 gagttcttaa aagatccaaa acgattcaca aaacttggag cccgtattcc agcaggtgtt
   116821 cttttggagg gacctccggg gacaggtaag actttgcttg ctaaggcagt cgctggagaa
   116881 gcaggtgttc cattctttag tatctcaggt tctgactttg tagaaatgtt tgtcggagtt
   116941 ggagctagtc gtgttcgctc tctttttgag gatgccaaaa aagcagcacc agctatcatc
   117001 tttatcgatg aaattgatgc tgttggacgt caacgtggag tcggtctcgg cggaggtaat
   117061 gacgaacgtg aacaaacctt gaaccaactt ttgattgaga tggatggttt tgagggaaat
   117121 gaagggatta tcgtcatcgc tgcgacaaac cgttcagatg tacttgatcc tgcccttttg
   117181 cgtccaggac gttttgatag aaaagtattg gttggccgtc ctgatgttaa aggtcgtgaa
   117241 gcaatcttga aagttcacgc taagaacaag cctttagcag aagatgttga tttgaaatta
   117301 gtggctcaac aaactccagg ctttgttggt gctgatttag agaatgtctt gaatgaagca
   117361 gctttagttg ctgctcgtcg caataaatcg ataattgatg cttcagatat tgatgaagca
   117421 gaagatagag ttattgctgg accttctaag aaagataaga cagtttcaca aaaagaacga
   117481 gaattggttg cttaccatga ggcaggacat accattgttg gtctagtctt gtcgaatgct
   117541 cgcgttgtcc ataaggttac aattgtacca cgcggccgtg caggcggata catgattgca
   117601 cttcctaaag aggatcaaat gcttctatct aaagaagata tgaaagagca attggctggc
   117661 ttaatgggtg gacgtgtagc tgaagaaatt atctttaatg tccaaactac aggagcttca
   117721 aacgactttg aacaagcgac acaaatggca cgtgcaatgg ttacagagta cggtatgagt
   117781 gaaaaacttg gcccagtaca atatgaagga aaccatgcta tgcttggtgc acagagtcct
   117841 caaaaatcaa tttcagaaca aacagcttat gaaattgatg aagaggttcg ttcattatta
   117901 aatgaggcac gaaataaagc tgctgaaatt attcagtcaa atcgtgaaac tcacaagtta
   117961 attgcagaag cattattgaa atacgaaaca ttggatagta cacaaattaa agctctttac
   118021 gaaacaggaa agatgcctga agcagtagaa gaggaatctc atgcactatc ctatgatgaa
   118081 gtaaagtcaa aaatgaatga cgaaaaataa ccctgagaga ggctggag
//
LOCUS       DBEJZJ010000003        88173 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000003 DBEJZJ010000000
VERSION     DBEJZJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 88173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.03"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(48..1937)
                     /locus_tag="ACL3R8_000231"
     CDS             complement(48..1937)
                     /locus_tag="ACL3R8_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR1313182.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2075..3640
                     /locus_tag="ACL3R8_000232"
     CDS             2075..3640
                     /locus_tag="ACL3R8_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR1313183.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3640..4404
                     /locus_tag="ACL3R8_000233"
     CDS             3640..4404
                     /locus_tag="ACL3R8_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1313184.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4603..4818)
                     /locus_tag="ACL3R8_000234"
     CDS             complement(4603..4818)
                     /locus_tag="ACL3R8_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313185.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="ACL3R8_000235"
     CDS             complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="ACL3R8_000235"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR1313186.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6989..7345)
                     /locus_tag="ACL3R8_000236"
     CDS             complement(6989..7345)
                     /locus_tag="ACL3R8_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR1313187.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7583..7819)
                     /locus_tag="ACL3R8_000237"
     CDS             complement(7583..7819)
                     /locus_tag="ACL3R8_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313188.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="ACL3R8_000238"
     CDS             complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="ACL3R8_000238"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR1313189.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="ACL3R8_000239"
     CDS             complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="ACL3R8_000239"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR1313190.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9483..11183)
                     /locus_tag="ACL3R8_000240"
     CDS             complement(9483..11183)
                     /locus_tag="ACL3R8_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR1313191.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11384..13051)
                     /locus_tag="ACL3R8_000241"
     CDS             complement(11384..13051)
                     /locus_tag="ACL3R8_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR1313192.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13054..13419)
                     /locus_tag="ACL3R8_000242"
     CDS             complement(13054..13419)
                     /locus_tag="ACL3R8_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1313193.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13576..13764)
                     /gene="rpmB"
                     /locus_tag="ACL3R8_000243"
     CDS             complement(13576..13764)
                     /gene="rpmB"
                     /locus_tag="ACL3R8_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR1313194.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13880..14056)
                     /locus_tag="ACL3R8_000244"
     CDS             complement(13880..14056)
                     /locus_tag="ACL3R8_000244"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1313195.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14167..14364)
                     /locus_tag="ACL3R8_000245"
     CDS             complement(14167..14364)
                     /locus_tag="ACL3R8_000245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313196.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14792..16336)
                     /locus_tag="ACL3R8_000246"
     CDS             complement(14792..16336)
                     /locus_tag="ACL3R8_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR1313197.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16549..16851
                     /gene="gatC"
                     /locus_tag="ACL3R8_000247"
     CDS             16549..16851
                     /gene="gatC"
                     /locus_tag="ACL3R8_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR1313198.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            16851..18317
                     /gene="gatA"
                     /locus_tag="ACL3R8_000248"
     CDS             16851..18317
                     /gene="gatA"
                     /locus_tag="ACL3R8_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR1313199.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAHVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TIQSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18317..19759
                     /gene="gatB"
                     /locus_tag="ACL3R8_000249"
     CDS             18317..19759
                     /gene="gatB"
                     /locus_tag="ACL3R8_000249"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR1313200.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEIAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19888..20448
                     /gene="efp"
                     /locus_tag="ACL3R8_000250"
     CDS             19888..20448
                     /gene="efp"
                     /locus_tag="ACL3R8_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR1313201.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20470..20859
                     /locus_tag="ACL3R8_000251"
     CDS             20470..20859
                     /locus_tag="ACL3R8_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1313202.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20852..21274
                     /gene="nusB"
                     /locus_tag="ACL3R8_000252"
     CDS             20852..21274
                     /gene="nusB"
                     /locus_tag="ACL3R8_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR1313203.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21324..21560)
                     /locus_tag="ACL3R8_000253"
     CDS             complement(21324..21560)
                     /locus_tag="ACL3R8_000253"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR1313204.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21573..22047)
                     /locus_tag="ACL3R8_000254"
                     /pseudo
     CDS             complement(21573..22047)
                     /locus_tag="ACL3R8_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22065..22250)
                     /gene="briC"
                     /locus_tag="ACL3R8_000255"
     CDS             complement(22065..22250)
                     /gene="briC"
                     /locus_tag="ACL3R8_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR1313205.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22409..23176)
                     /locus_tag="ACL3R8_000256"
     CDS             complement(22409..23176)
                     /locus_tag="ACL3R8_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR1313206.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23173..24039)
                     /gene="accD"
                     /locus_tag="ACL3R8_000257"
     CDS             complement(23173..24039)
                     /gene="accD"
                     /locus_tag="ACL3R8_000257"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR1313207.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24076..25443)
                     /gene="accC"
                     /locus_tag="ACL3R8_000258"
     CDS             complement(24076..25443)
                     /gene="accC"
                     /locus_tag="ACL3R8_000258"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR1313208.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25455..25877)
                     /gene="fabZ"
                     /locus_tag="ACL3R8_000259"
     CDS             complement(25455..25877)
                     /gene="fabZ"
                     /locus_tag="ACL3R8_000259"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR1313209.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(25874..26359)
                     /gene="accB"
                     /locus_tag="ACL3R8_000260"
     CDS             complement(25874..26359)
                     /gene="accB"
                     /locus_tag="ACL3R8_000260"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR1313210.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26362..27597)
                     /gene="fabF"
                     /locus_tag="ACL3R8_000261"
     CDS             complement(26362..27597)
                     /gene="fabF"
                     /locus_tag="ACL3R8_000261"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR1313211.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27619..28350)
                     /gene="fabG"
                     /locus_tag="ACL3R8_000262"
     CDS             complement(27619..28350)
                     /gene="fabG"
                     /locus_tag="ACL3R8_000262"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR1313212.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28384..29304)
                     /gene="fabD"
                     /locus_tag="ACL3R8_000263"
     CDS             complement(28384..29304)
                     /gene="fabD"
                     /locus_tag="ACL3R8_000263"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR1313213.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29297..30271)
                     /gene="fabK"
                     /locus_tag="ACL3R8_000264"
     CDS             complement(29297..30271)
                     /gene="fabK"
                     /locus_tag="ACL3R8_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR1313214.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30390..30614)
                     /locus_tag="ACL3R8_000265"
     CDS             complement(30390..30614)
                     /locus_tag="ACL3R8_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR1313215.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30674..31648)
                     /locus_tag="ACL3R8_000266"
     CDS             complement(30674..31648)
                     /locus_tag="ACL3R8_000266"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR1313216.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31648..32082)
                     /locus_tag="ACL3R8_000267"
     CDS             complement(31648..32082)
                     /locus_tag="ACL3R8_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR1313217.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32176..32961)
                     /locus_tag="ACL3R8_000268"
     CDS             complement(32176..32961)
                     /locus_tag="ACL3R8_000268"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR1313218.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33286..34650
                     /locus_tag="ACL3R8_000269"
     CDS             33286..34650
                     /locus_tag="ACL3R8_000269"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR1313219.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34653..35024
                     /locus_tag="ACL3R8_000270"
     CDS             34653..35024
                     /locus_tag="ACL3R8_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR1313220.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35238..36512
                     /gene="serS"
                     /locus_tag="ACL3R8_000271"
     CDS             35238..36512
                     /gene="serS"
                     /locus_tag="ACL3R8_000271"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR1313221.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDTKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36537..37436)
                     /locus_tag="ACL3R8_000272"
     CDS             complement(36537..37436)
                     /locus_tag="ACL3R8_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR1313222.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37546..38094)
                     /locus_tag="ACL3R8_000273"
     CDS             complement(37546..38094)
                     /locus_tag="ACL3R8_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR1313223.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38312..39634)
                     /locus_tag="ACL3R8_000274"
     CDS             complement(38312..39634)
                     /locus_tag="ACL3R8_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR1313224.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39725..39813)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39977..42313)
                     /locus_tag="ACL3R8_000275"
     CDS             complement(39977..42313)
                     /locus_tag="ACL3R8_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR1313225.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEKLARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDIFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42417..42965)
                     /locus_tag="ACL3R8_000276"
     CDS             complement(42417..42965)
                     /locus_tag="ACL3R8_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR1313226.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42962..43264)
                     /gene="zapA"
                     /locus_tag="ACL3R8_000277"
     CDS             complement(42962..43264)
                     /gene="zapA"
                     /locus_tag="ACL3R8_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR1313227.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43351..44232
                     /gene="rnhC"
                     /locus_tag="ACL3R8_000278"
     CDS             43351..44232
                     /gene="rnhC"
                     /locus_tag="ACL3R8_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR1313228.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEKKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44236..44850
                     /gene="lepB"
                     /locus_tag="ACL3R8_000279"
     CDS             44236..44850
                     /gene="lepB"
                     /locus_tag="ACL3R8_000279"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR1313229.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45129..47495
                     /locus_tag="ACL3R8_000280"
     CDS             45129..47495
                     /locus_tag="ACL3R8_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR1313230.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47543..48826)
                     /gene="tig"
                     /locus_tag="ACL3R8_000281"
     CDS             complement(47543..48826)
                     /gene="tig"
                     /locus_tag="ACL3R8_000281"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR1313231.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49020..49379)
                     /locus_tag="ACL3R8_000282"
     CDS             complement(49020..49379)
                     /locus_tag="ACL3R8_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1313232.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49681..50271)
                     /gene="cbpG"
                     /locus_tag="ACL3R8_000283"
                     /pseudo
     CDS             complement(49681..50271)
                     /gene="cbpG"
                     /locus_tag="ACL3R8_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(50352..50591)
                     /locus_tag="ACL3R8_000284"
     CDS             complement(50352..50591)
                     /locus_tag="ACL3R8_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313233.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50741..51283)
                     /locus_tag="ACL3R8_000285"
                     /pseudo
     CDS             complement(50741..51283)
                     /locus_tag="ACL3R8_000285"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51265..51507)
                     /locus_tag="ACL3R8_000286"
     CDS             complement(51265..51507)
                     /locus_tag="ACL3R8_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGR1313234.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51508..52140)
                     /locus_tag="ACL3R8_000287"
     CDS             complement(51508..52140)
                     /locus_tag="ACL3R8_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1313235.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52154..53149)
                     /locus_tag="ACL3R8_000288"
     CDS             complement(52154..53149)
                     /locus_tag="ACL3R8_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1313236.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53146..53844)
                     /gene="liaF"
                     /locus_tag="ACL3R8_000289"
     CDS             complement(53146..53844)
                     /gene="liaF"
                     /locus_tag="ACL3R8_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR1313237.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKNYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(53922..54932)
                     /gene="fni"
                     /locus_tag="ACL3R8_000290"
     CDS             complement(53922..54932)
                     /gene="fni"
                     /locus_tag="ACL3R8_000290"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR1313238.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLHTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVLGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(54916..55923)
                     /locus_tag="ACL3R8_000291"
     CDS             complement(54916..55923)
                     /locus_tag="ACL3R8_000291"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR1313239.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(55910..56863)
                     /gene="mvaD"
                     /locus_tag="ACL3R8_000292"
     CDS             complement(55910..56863)
                     /gene="mvaD"
                     /locus_tag="ACL3R8_000292"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR1313240.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(56845..57723)
                     /gene="mvk"
                     /locus_tag="ACL3R8_000293"
     CDS             complement(56845..57723)
                     /gene="mvk"
                     /locus_tag="ACL3R8_000293"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR1313241.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57845..58861)
                     /gene="cbpC"
                     /locus_tag="ACL3R8_000294"
     CDS             complement(57845..58861)
                     /gene="cbpC"
                     /locus_tag="ACL3R8_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR1313242.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            complement(58959..59648)
                     /locus_tag="ACL3R8_000295"
     CDS             complement(58959..59648)
                     /locus_tag="ACL3R8_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1313243.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(59660..61084)
                     /gene="gndA"
                     /locus_tag="ACL3R8_000296"
     CDS             complement(59660..61084)
                     /gene="gndA"
                     /locus_tag="ACL3R8_000296"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR1313244.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(61160..62554)
                     /gene="mapZ"
                     /locus_tag="ACL3R8_000297"
     CDS             complement(61160..62554)
                     /gene="mapZ"
                     /locus_tag="ACL3R8_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR1313245.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(62566..63723)
                     /locus_tag="ACL3R8_000298"
     CDS             complement(62566..63723)
                     /locus_tag="ACL3R8_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR1313246.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(63808..64188)
                     /gene="rnpB"
                     /locus_tag="ACL3R8_000299"
     ncRNA           complement(63808..64188)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3R8_000299"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(64209..64538)
                     /gene="gpsB"
                     /locus_tag="ACL3R8_000300"
     CDS             complement(64209..64538)
                     /gene="gpsB"
                     /locus_tag="ACL3R8_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR1313247.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(64608..65135)
                     /locus_tag="ACL3R8_000301"
     CDS             complement(64608..65135)
                     /locus_tag="ACL3R8_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR1313248.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            65201..65797
                     /gene="recU"
                     /locus_tag="ACL3R8_000302"
     CDS             65201..65797
                     /gene="recU"
                     /locus_tag="ACL3R8_000302"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR1313249.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            65794..67953
                     /gene="pbp1a"
                     /locus_tag="ACL3R8_000303"
     CDS             65794..67953
                     /gene="pbp1a"
                     /locus_tag="ACL3R8_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR1313250.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAA
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(68120..73423)
                     /locus_tag="ACL3R8_000304"
     CDS             complement(68120..73423)
                     /locus_tag="ACL3R8_000304"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR1313251.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTASTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSIKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HSRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKLVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYSFVVGKGEFQSGRRGTQASNLEIHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(73723..75705)
                     /locus_tag="ACL3R8_000305"
     CDS             complement(73723..75705)
                     /locus_tag="ACL3R8_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313252.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVDLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMIPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(76281..77519)
                     /locus_tag="ACL3R8_000306"
     CDS             complement(76281..77519)
                     /locus_tag="ACL3R8_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR1313253.1"
                     /translation="MKIAVTGTGYVGLSIAVLLAQHHQVIAVDIIPEKVELINQRKSP
                     IQDDYIEKYLAEKDLNLVATLDAKEAYKDADFVVIAAPTNYDPKKNFFDTSAVESVIE
                     TVLKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
                     GTDKNNERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPE
                     ELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNVFNERVEKDIIIGIYRLTMKSNSD
                     NFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSIINDLEEFKRLSNAIVANRY
                     DNSLEDVKEKVYTRDIFERD"
     gene            complement(77588..78751)
                     /gene="cap8K"
                     /locus_tag="ACL3R8_000307"
     CDS             complement(77588..78751)
                     /gene="cap8K"
                     /locus_tag="ACL3R8_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase Cap8K"
                     /protein_id="HGR1313254.1"
                     /translation="MPYLNNVPQNKFSIRLFDIAIVLLTLKMLVSSIPVFDFVFPQKF
                     QNILVILGYILIFLHIFEKRKYTLQFIISIILITTLLLYTSIQMQNYVYFTSWFMLIG
                     TIHYDLRRVIKIIFIVSLSIMFISIFISLLMYIIDYKREILINIRRNETVRAFTFGFI
                     HPNKFTIVLSNLCLMFIWLIKDRLKYYHVTFCLFIQLFFYFFTQTRTALLVSIVIFAL
                     LYIYMFVENLELRWIGYSFFCISTFLGVLAFQFYPSNNKFSIFIDNILTGRIKLAAYA
                     RTFFGYTFWGQYVDKEIVWDPIWGLTSFTFDSFYSFLMSNAGIIWLLILSVLFVKLQK
                     YLDNKSLILLLAWSMYAVTETDLIFPSYGFQFLFLSILFTNTSTCSTIMLKNN"
     gene            complement(78735..79463)
                     /locus_tag="ACL3R8_000308"
     CDS             complement(78735..79463)
                     /locus_tag="ACL3R8_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 32 protein"
                     /protein_id="HGR1313255.1"
                     /translation="MIPKKIHYIWFGGSEKPDVVLKCINSWKKYMPDYEIVEWNEDNF
                     DLSDSQFAKSAYESRKWAFASDYARFKILSKYGGIYFDTDVELLKTIPDDILAHSSFT
                     GFEYIGEVNPGLVYACMPDDKIAKYMVQYYEQASFDINHLVTVNTIITDYLLKNNFQK
                     NNQFQIIDGLAIYPDDYFCGYDQEVKEVRLTERTISIHHYSATWKTRTLKRKVQMIVK
                     TIIGAENYRKLLYCKRKITNAVSK"
     gene            complement(79476..80936)
                     /locus_tag="ACL3R8_000309"
     CDS             complement(79476..80936)
                     /locus_tag="ACL3R8_000309"
                     /inference="COORDINATES: protein motif:HMM:NF014051.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGR1313256.1"
                     /translation="MTKKSITRNFIFNTILTMSSFIFPLISFPYVSRVLMADGLGRVT
                     FASSIIDYALTFAMLGMPLYGVKVCAGYIKNKEKLSQTVRELLVINLLVGFLVMLLLA
                     TMVIIIPRFRQEWQLIIITSSTIPLNIIGIEWLYKALEDYSYISIRTLTFKILGFLLM
                     FLVVRTKDDYMVYAAITVLASHGSFILNFFRSRTFLLENISQRLNLKQHIKPLLILFF
                     LSVSWTIYKNTDVVMMGFLTSDTEIGYYSTALKIRSIVLSVVTSLGTVVLPRLVKYYK
                     EGKYNEAKKILNKSSSFIMLSSLYFIGYIVINAREIILFIAGRNYLGAIPTLQVSIFS
                     AIFVGYSIMYGTNILVSIGKENVTIQASIIGVVLNICLNFIMIPKFAALGAGIATSIG
                     EAVMVLYEIIYLGKDGWSYFERLNILKIIVVFIFSTFMLYIMKDFFVGYPLFIYIVIS
                     GVIYSIIYIFGLMILRENLLSSWKISILNRFNIIKE"
     gene            complement(80936..82000)
                     /locus_tag="ACL3R8_000310"
     CDS             complement(80936..82000)
                     /locus_tag="ACL3R8_000310"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1313257.1"
                     /translation="MTKVLQIGPSINLSKGGMSAVIRDLTYSPLLSGDFDITAYQSFI
                     DGSLVTRLTYSSYALLKFVVHSGNYDIYHIHTATRGSCWRKLLYLKLLKSKNKKAILH
                     IHGAEFQIFYDSLPEYKKNKVREMLELSDYVIVLSQTWYDFFSNININAKIVIVENGV
                     DTSFYVEKKKSITSNNFLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLTMAGDGELED
                     IRQKISNLNLTDHITIYDWVNQRDKKILFQANQTLILPSYNEGLPMAILEAMASGLAI
                     ISTPVGGIPEIIHEDNGWLIQPGDISQLSNIILEASYNPDVVSLMGSNNHKLVEEKYS
                     FHSMHGKIKKIYNTLLETKK"
     gene            complement(82013..82492)
                     /gene="pssE"
                     /locus_tag="ACL3R8_000311"
     CDS             complement(82013..82492)
                     /gene="pssE"
                     /locus_tag="ACL3R8_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssE/Cps14G family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGR1313258.1"
                     /translation="MIFITVGTQKHPFNRLLKKIDQLIELEVIKEEVFAQIGASDYKP
                     KYFSYNSFLSSIDMNEKMREASMVITHGGTASIVKALKLRKKIIAVPRLEQFGEHVDN
                     HQLQIITVLGEEGYILPCFDIEQLGTVYQKAQTFTTKPYISNSYALLEDIRQYIDSL"
     gene            complement(82493..82972)
                     /gene="pssD"
                     /locus_tag="ACL3R8_000312"
     CDS             complement(82493..82972)
                     /gene="pssD"
                     /locus_tag="ACL3R8_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGR1313259.1"
                     /translation="MKNKKKVCFCASSGGHYEQLMKLEPIMRQQDSYLITEYTDYNKG
                     ESEKKDINKVFYLLQINRLEFFWIVKLIWISLKSLYILLRIRPKVVICTGVLAMIPFC
                     LLSKMFGAKLIYIESFAKVTTPTLTGRILYRYADRFYVQWESMLDIYPNAVYKGGLY"
     gene            complement(82977..84344)
                     /locus_tag="ACL3R8_000313"
     CDS             complement(82977..84344)
                     /locus_tag="ACL3R8_000313"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR1313260.1"
                     /translation="MNGKVVNSSLAIIHSFLVILLTYLLSAVREAEIASATAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVIFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSVVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTM
                     QGGMFKVDDDPRITKVGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(84359..85048)
                     /locus_tag="ACL3R8_000314"
     CDS             complement(84359..85048)
                     /locus_tag="ACL3R8_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR1313261.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNSLCMNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVNKYGSY
                     GNYGDYGKNKK"
     gene            complement(85058..85750)
                     /locus_tag="ACL3R8_000315"
     CDS             complement(85058..85750)
                     /locus_tag="ACL3R8_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HGR1313262.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVTVPTDTRIVSISVKDKQPEEASRIANSLREVAVERIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELFDTRVKRPEDVEDVLQIP
                     LLGLVPDLDKMK"
     gene            complement(85759..86490)
                     /gene="cps4B"
                     /locus_tag="ACL3R8_000316"
     CDS             complement(85759..86490)
                     /gene="cps4B"
                     /locus_tag="ACL3R8_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR1313263.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAESFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALGNNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQNLVHVIASDMHNLDGRPPHMAEAYDFVT
                     QKYGEAKAQELFIDNPRKIIMDQLI"
     gene            complement(86492..87937)
                     /gene="cps4A"
                     /locus_tag="ACL3R8_000317"
     CDS             complement(86492..87937)
                     /gene="cps4A"
                     /locus_tag="ACL3R8_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR1313264.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLVAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTSRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVLLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYMMEIDDSSLAVVKAAIQDVMEGR"
BASE COUNT        26173 a        19797 c        15834 g        26369 t
ORIGIN      
        1 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
       61 atactgccgc cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      121 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg cgcgcttgaa
      181 tgataaaaca gactgtgcca gccataagct acatagagat tgatatctgg attttccact
      241 tgaatctgat gaaccttcat caaatgacta accttgtccg catagccaaa taaggtcgca
      301 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      361 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      421 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      481 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      541 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      601 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
      661 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
      721 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
      781 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
      841 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
      901 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
      961 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1021 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1081 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1141 ataaaataga agcagacact caataacaag gagatagaaa ggatcgaagg gaggacccaa
     1201 gtaacaagtt gtttactctg atctttttct ctaacaatcg agtcttctat cttattaaac
     1261 tcttctaaac gattcccttt caatccctga tccctagcgc tagcaaaatc ggtccgaggc
     1321 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1381 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1441 ttttcagctc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1501 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1561 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1621 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     1681 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     1741 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactggta aactatcttc
     1801 tgtctaaact ctgccgtatt atctgcatga atatacaaat ccccttgata agagtttatc
     1861 ttgaaatcaa tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag
     1921 aaaaaagttt ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt
     1981 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2041 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2101 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2161 catcgggatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2221 agctgtcaaa atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2281 gaaaatcgct aaggacttag gtaaaaaacc tttggttgtt aaaaccaagt gggaaggtct
     2341 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2401 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttttgct
     2461 tgtcaaaaaa gattctgcct acgcaagtgc taaatctttg gatgacttta acggtgcaaa
     2521 aatcacttct caacaagggg tctacctcta cgacttgatt gcacaaatcc caggtgctaa
     2581 aaaagaaaca gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat
     2641 tgatgcttat gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt
     2701 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     2761 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     2821 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     2881 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     2941 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3001 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3061 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3121 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3181 tttcggtatc aaccttgacc gtacactagc tgctatcttc atcgtttcaa tcaataccgg
     3241 tgcctacatg actgaaattg tccgtggtgg tatcctggca gttgacaagg gacaatttga
     3301 agctgcgact gctcttggta tgactcataa ccaaaccatg tgtaagattg tcctacctca
     3361 ggttgtccgc aatatcctac cagcaactgg taatgaattt gtcatcaata tcaaagatac
     3421 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3481 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3541 cttcaccgta acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac
     3601 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     3661 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttctctcact
     3721 gtccacaagg gagaagttat ttctatcatc ggaagctctg gaagtgggaa atcaaccttc
     3781 ctacgctcca ttaacctact tgaaacgcca actgatggac aaatccttta tcatggacaa
     3841 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttagg gatggttttc
     3901 caatccttta acctctttga aaatctcaac gttcttgaaa acacaatcgt cgctcagaca
     3961 actgtcctta aacgcgaacg cacagaagct gaagaaattg ccaaagaaaa cctggaaaag
     4021 gtcggcatgg gagaacgcta ctggcaagcg agacccaaac aactctcagg tggtcaaaaa
     4081 caacgtgtgg ccatcgctcg tgccctttca atgaatcctg acgccattct ctttgatgaa
     4141 ccaacatcag ctctcgatcc agaaatggtt ggagaggtcc tcaaaatcat gcaagatctg
     4201 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc
     4261 tctcaccgtg ttatctttat ggataagggt gtgattgctg aagaaggtaa accagaagac
     4321 ctcttcacta atcctaaaga agaccgtaca aaagaatttc ttcaacgtta tctcatactc
     4381 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actgttttga
     4441 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatcaa ataaaaagaa
     4501 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     4561 tctctactac ttgaaggtca agaatccacc gttatccaaa gattaatctt caaatttttc
     4621 atgatttttt tcatagaaat caattaagcc tagggctgtt tcaaatgaaa tattttttac
     4681 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     4741 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     4801 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     4861 gtttttacta cttttgtcaa aaaaaaaaac atatattcaa cgaaaataat tagttcagaa
     4921 ttttcttact tcctttttaa atccgataat atataggttt tgctagcctc tacaccataa
     4981 atatttgcta ataaaaatac tgtattatta ccctcttaag gtgcaaaatt attcaagttc
     5041 ttaaaaaatg cttctctatt tccgtaagat agcttatttc ttcgatttaa gaactgaaga
     5101 tgatagttct aacctttaga aatccaagcc ttctctagct caaaaactcc tatctttctt
     5161 cctcaataaa tcatctgaga gataggtatt ccttatatcc ttcaaattca tcactccttt
     5221 ggatattgag gtgctagcct agaagcagac acccgattat ctaaaccatc cttaatagag
     5281 atgacaagac agataagctc agttaattac ttatatatct ttttaatatg gtatatttgt
     5341 caacaaaaag aaatcaaatc ataccttata ctcaatgaaa atcaaagagc aaactaggaa
     5401 gctagccgca aattgctcaa aacactgttt tgaggtttca gatagagcta acgtggtttg
     5461 aagagatttt cgaagagtat taaagacagt atgactatgc ttgtcaatag ataggaaatc
     5521 aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac agaagtaaga
     5581 attgcacgat aagttttcta aaaccatagg aatcgtcccc tttcttcatc ttcattatag
     5641 cacatataca tcagttgtac aaataatatg atattttttt attagtcctc agacaagcat
     5701 attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac cttccattct
     5761 acggatcaaa cctgcataat catgcttatc tgccaaagcg atcccaatca atactgggcc
     5821 tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat ttggccccag
     5881 gatatcattt acaaactcac gcaaagctcc tggacgctgt gggaaattga ccacaaagta
     5941 atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac ggttgatatc
     6001 attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt cagctaaaac
     6061 ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt gcttagagta
     6121 aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag tttgaatatg
     6181 ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc catccgcaaa
     6241 tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt tcatggaacg
     6301 cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct tgatataggt
     6361 agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat caaaatcaat
     6421 cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac ctgcttgaac
     6481 atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa attcttgagc
     6541 tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa aatccccacc
     6601 aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa agatagtagc
     6661 aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc ccgcagaagc
     6721 gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat aataggcacc
     6781 acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa tcttagcacc
     6841 atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca caccgttcaa
     6901 gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct ttttctataa
     6961 aaaacagtca ctaatgactg ttttttagtt attcatctcc gaaaacttca gtaacacttt
     7021 catggtattt atgagccata cgaatcgaaa actctttagg aagttcataa cgatttgtgg
     7081 aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga tggaagataa
     7141 aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct acaaattgac
     7201 tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct cccaattgta
     7261 aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat cctgtcttga
     7321 tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac atctaatatc
     7381 ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga ttctttcaat
     7441 ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc atttattctg
     7501 cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga tttaggtcct
     7561 aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat ttcgctatat
     7621 aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca agaccttctt
     7681 ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt catatgcaac ctaccatctt
     7741 caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac caatctgctt
     7801 tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac tagaaccaat
     7861 aataacgatg caatttttct cataatcttt ttcataaaat catctccagc gctatatatt
     7921 tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacaaa tggcattgct
     7981 ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc acggtaagca
     8041 gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa tttaccattt
     8101 tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat tacacgtgga
     8161 cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat tttcttgaat
     8221 ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc aaagtaagcc
     8281 aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat aagggcagtc
     8341 aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc ttctttgtaa
     8401 gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc catagcaatg
     8461 tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac accaaatcct
     8521 tcttcgtaag tacgacgtac caagtgtccc ggtcctttag gagcacacat gaagacatct
     8581 acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc aaatccaact
     8641 gcgtttccag cttccaagtt tggagcgatt tctgcttcgt acaattcttg ttgaatttcg
     8701 tctggcgcca agatcatgat aacatcagcc aacttagtag cttctactac tgtgtaagta
     8761 tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc gataataacg
     8821 tcacgacctg aatcacgcaa gttttgagca tgcgcatgtc cttgtgaacc ataaccgata
     8881 acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata ttccatttga
     8941 actgtcatag cttttctctc ttttctatta tttattgcct tttaggctgg tttaataaat
     9001 ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca atattgcgaa
     9061 taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt cccgtcatct
     9121 gaatggtaat cgagcttggc gctacgtcta ccactgttgc acggaaaggt tgaataatcg
     9181 ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc acctcgcgct
     9241 ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga cgattgagct
     9301 gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata gtgatacgcg
     9361 atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc tgacgacgag
     9421 ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt gctgttaaca
     9481 ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc cggtaccatt
     9541 ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac atcctcagtg
     9601 atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt tttaatacca
     9661 taagcctgcg ccatcaattg gaaatcagga agggtatcaa agaccgactc tgatgttctg
     9721 ccttcataga aggattcctg ccactggcga accattccaa gtgaatgatt gttcagcata
     9781 accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt ggtcatttgg
     9841 aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat tttagcaccg
     9901 attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac taactgacgc
     9961 tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac gtctgttacc
    10021 acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg cggttgaacc
    10081 acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac tttctcaatc
    10141 cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa ggccttctta
    10201 gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc tgggtcaata
    10261 tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt caaacggtca
    10321 tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat atttgctgcg
    10381 aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc aatcgttcct
    10441 tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc atttagttcc
    10501 gtagcagcct cagcataact aattccacca ccagctaaca agactggctt tttagccttg
    10561 gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt cggctgataa
    10621 cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga tatgtctttt
    10681 ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac agcttccgta
    10741 atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt gattggcatg
    10801 gtaattccta cgatgtctgc ctcctgaaag gcatccttcc caatccctgc tcgcgccacc
    10861 tgacctgtaa agaccaaaag gggaacgcta tcgctcatag catccgcaat ccctgtaatg
    10921 gcatttgttg ctcctggtcc actagtgacg acggcaacac ccaactttcc agttgatttg
    10981 gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat gtggcgaatg
    11041 cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg ataaccaaag
    11101 atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc cgtcttagga
    11161 gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat aacttgttac
    11221 tatcatacca ttttttcaaa atttttcaag ataaaagaag aaattttctg aattttctat
    11281 tttaacgttt atttatgaat gttatttttg tttttattaa aaagataccg atttcattta
    11341 ctaaaaaaga aaaaagaact gatttctcag tccttcatta atcttattcc acactaaata
    11401 ggtatgggta aacaggttgt tgaccttggt gaatctcgac ttcaacgtct tcgaattctt
    11461 ctacgatttc ttgagcgatt tcattggcaa gttcttcgct tccgtcttca ccgacataga
    11521 aggttacgat ttcactatct tcatccaaca tatgtttcaa ggtttcagtc aatgtttggt
    11581 gcatatcagg gtttgacaca agaatttttc catccaccat acctagatta tcgttttcat
    11641 ggatttctaa gccatcgatc gttgtatcac gcacggctgt tgtgacgctt ccgctaacga
    11701 catcgctaag agcagctgtc atacgctctt ggttttcttc aatggacttg cttggatcaa
    11761 aggcaagaag acttgtcata ccttgaggaa gagtgcgagc ctctaccact actgctggtt
    11821 gctccaaaac ttctgccgca gattgagctg ccatgaagat gttcttgttg tttggcaaga
    11881 agatgatgtt acgggcattg acctgttcaa cagccttgat aaagtcttct gttgaagggt
    11941 tcatggtttg accgccttcg ataacataat ccacgccttg agaacagaag atatctgcta
    12001 gacctttacc agccaccaca gcaatcaaag catactcttt ttcttcagcc gacttgataa
    12061 cttgagtagc ttctttctca acctgtgctt cgtgttggtt acgcatattg tcaactttta
    12121 ccttgaccaa gctaccatat ttgagacctt cttgcataac aagtcctgga tcttctgtat
    12181 gaacatggac tttgacaatt tcatcatcgt taacaacgag gagagaatcc ccaagctcat
    12241 ccaagtagtt acggaattca tcgtagtcaa aatctttagc ataggttgga ccttgcttaa
    12301 gagctaccat gatttcagta cagtaaccaa acgtgatgtc ctcagtcgct acgtgaccag
    12361 ctacagactt atgatgctct acattgatca tctcactcat gttggcagga gtcgctacaa
    12421 agtcctcaga tgcaatatat tcgccagtaa gggctgaaag gaaaccttcg tagatgaaga
    12481 ccaatccttg accacctgag tccacaacgc caacttcttt caatactgga agcatgtctg
    12541 gtgttttagc tagagctgtt ttagcacctt ccaaggctgc gcgcatgact tcaacagtgt
    12601 catctgtttg ctcagctttt ttcttagcac cgatagcagc tccacgagaa actgtcaaaa
    12661 tcgttccttc aacaggtttc atcactgcct tataggcaac ttccacacct gattggaagg
    12721 ccagagccaa gtcttgacct gttaactcgt ctttatcctt gatagcttgg gaaaatccac
    12781 ggaaaagctg agacgtaatc actcctgagt tcccacgcgc acccatcaaa agccctttgg
    12841 caagaatgct cgctacttct ccaactgtag aagctggctt gtctgcaact tctttagcac
    12901 cattttcaat ggtcattccc atatttgtcc cagtatctcc atctggaact ggaaagacgt
    12961 ttaatgaatt gacatattca gcttgcttat tcaagcgagt tgatgcagcc tgcaccattt
    13021 cttgaaataa gctagtagta atttttgaca cggttattct cctacaactt tgatattttg
    13081 aatgtagaca tttacagtct gagcagtaat tccaagctgg ttttccaagc taaaggcaac
    13141 acgctcttga atgttttttg acacttcact aatctttgtt ccgtagctta acacggtata
    13201 tacatcaact gcaatactgc catcttcggc tgcctttacg acgacacctt tagaataatt
    13261 ttccttacct agcagggctt ggaaattatc tttgagggca tttttactag ccataccgac
    13321 cacaccaaaa atctcagttg ctgctccacc tacgacggtt gcaatcactt catctgttag
    13381 ttcgatttga ccatcttttg tattaatttt tacagtcatc ctttttacct caactagttg
    13441 atactctatt ttatcatatt tcagcccaag tgtaaaagca gaatgatgta tcagcggata
    13501 tttactctat ttttcaaacg atgttatacc cacaataaaa gaaaaaagac cctaaggtct
    13561 cctttgcttt tattattaaa cgcgttcaac tttacctgat ttcaaagcac gagctgaagc
    13621 ccaaactttt ttaggtttac catcgataag aacagtaact ttttgaaggt ttggttttac
    13681 ggcacgtttt gtttggttca tcgcgtgtga acggttgttt cctgatacag tcttacgacc
    13741 tgtaaagtaa catactttag ccattgtgtt ttcctcctat tagatctaat atagcggatg
    13801 tgctagcacc acataccgta ctatgttatc acactttctt gttttttgca agggaattgg
    13861 aagatttttt atttgtgtct taaatcaggt cttgcgtgac attttctgct ctccacatgc
    13921 catcgttgat taacagaaca ccagaattaa aattatgtgt ataaaaatca tctctaactg
    13981 cagctaaggg tatagccgtc aagtccaaat cccacagctc atctatcgat tttcttacaa
    14041 caatatctga atccaaatac agtacacgag actcgcttac atactttgga ataaaatacc
    14101 taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga taacctttca gaatactact
    14161 gtcaatctaa acattcacaa tctcactatt caaagtctct agtctttttt ccattaattg
    14221 gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat aatgatgaac
    14281 acaaagagat tttattgttg tttcaacttt atccatataa gcattatctg cacctaagac
    14341 aatcgctttt ttctcttctt tcacttttta tctcatttct ttttattccc atcatatgtt
    14401 tctacgtaac cattattttc gcctattcgt tcgtaaaacc ataccagtgg agattttaga
    14461 tgaagtccca ttacggttta caatttttac attacgacac agagttttac aaatcgattt
    14521 catttgccaa acgtagttag taaggcagtt agctaggcta cctactttct gctacgacgg
    14581 aaaaatccac aaatcaatac cattcgtgga tttttcctag tgaagcgttt aggtaagccg
    14641 ccatagcggt taccgattat tagattacga cacggagttt ggcaaatcga ttctatttgc
    14701 caaacgtagt tagtgaggca gttagctagt tcgccaaata gcgactagcg tccaacaatt
    14761 tggaacttta gttccaattg ttggtactga gtcacatctt ctcctctaac tctacgtctg
    14821 gatacttgtc cgcaaaccag cggagggcaa agtcattttc aaagagaaag actggttggt
    14881 caaaacggtc tttggctaag atattgcgac ttgacgacat ccgttcatcc aagtcctcag
    14941 gcttgatcca acgaacggtc tttttaccca ttgggctcat gaccacttcc gcattgtatt
    15001 cgccttccat acggtgttta aagacttcaa actggagttg accaacagct cccagcatgt
    15061 actcacctgt ttggtaattc ttataaagct gaacggctcc ttcttgcacc aattgctcaa
    15121 tccccttgtg gaaggatttt tgcttcataa cattcttagc agaaactttc atgaaaattt
    15181 caggagtaaa ggttggcaat ggttcaaatt caaacttgtt ttttccaacc gtcaaggtat
    15241 ccccaacctg ataagtaccg gtatcgtaaa ccccgataat atcacctgcc acggcattgg
    15301 tcacattctc acgactctcc gccataaact gggtaacatt agatagttta gcccccttac
    15361 cagtacgagg gagattgaca ctcatgccgc gctcaaattc gcctgatacg atacggacaa
    15421 aggcaatacg gtcacggtga cgaggatcca tgttggcttg gattttaaag acaaagcctg
    15481 agaaatcctt gtcataagga tccacaattt caccatctgt tttcttgtga ccatgtggtt
    15541 ctggagcaaa cttgaggaag atttcaagga aggtctgcac accaaagttt gtcagggctg
    15601 aaccgaaaaa gacaggcgtc aattctccag ccagaatagc ttcctctgaa aactcattcc
    15661 cagcttcatt taaaagctca atgtcatcct tgacttgctc gtagaaagga ttgctaccaa
    15721 aaagtttgtc tccatcttct aggctagcaa aacgctcatc ccctttataa agttctaaac
    15781 gttggttata gaggtcatac aagccctcaa aggctttccc catcccgata ggccagttca
    15841 tagggtagct agcaatgccc aagatttctt ccaattcttg caagagttcc aaaggctcac
    15901 gaccgtcacg gtccagcttg ttcataaagg taaagactgg aatgccacga tgtttcacaa
    15961 cctcaaacaa tttcttggtt tgagcctcga tccccttggc agagtccacg accatgaccg
    16021 cagcatccac cgccatcaag gtacgatagg tatcttctga gaagtcctcg tgccctggcg
    16081 tgtctaagat attcacgcgc ttgccgtcgt agtcaaattg cataacagat gaagtaacag
    16141 aaatcccacg ttgcttctcg atatccatcc agtcagattt agcaaaagtc cctgttttct
    16201 tcccttttac cgtaccagcc tcacgaatct cacccccaaa gtagagtaac tgctcagtga
    16261 tggttgtttt ccccgcgtcc gggtgggaga taatggcaaa ggtacgacgt ttcttaattt
    16321 cttcttgaat attcataagt tctctttctt tgattctcta tttttcttgt ttcaatagct
    16381 gagaatgatt tttacattgg attttaccat tcctttcaat actccattat atcggatttt
    16441 agcatttttt tcaatttcta tttcttttca cttccccctc ccttatttat aggaaaatat
    16501 ggtaaaatag aacagactaa aaatcatcat ttcacgaaag gatgcaagat gaaaattacg
    16561 caagaagagg taacacacgt tgccaatctt tcaaaattaa gattctctga agaagaaact
    16621 gctgcctttg cgaccacctt gtctaagatt gttgacatgg ttgaattgct gggcgaagtt
    16681 gacacaactg gtgtcgcacc tactacgact atggctgacc gcaagactgt actccgccct
    16741 gatgtggccg aagaaggaat agaccgtgat cgcttgttta aaaacgtacc tgaaaaagac
    16801 aactactata tcaaggtgcc agctatccta gacaatggag gagatgccta atgactttta
    16861 acaataaaac tattgaagag ttgcacaatc tccttgtctc taaggaaatt tctgcaacag
    16921 aattgaccca agcaacactt gaaaatatca agtctcgtga ggaagccctc aattcatttg
    16981 tcaccatcgc tgaggagcaa gctcttgttc aagctaaagc cattgatgaa gctggaattg
    17041 atgctgacaa tgtcctttca ggaattccac ttgctgttaa ggataacatc tctacagacg
    17101 gtattctcac aactgctgcc tcaaaaatgc tctacaacta tgagccaatc tttgatgcga
    17161 cagctgttgc caatgcaaaa accaagggca tgattgtcgt tggaaagacc aacatggacg
    17221 aatttgctat gggtggttca ggtgaaactt cacactacgg agcaactaaa aacgcttggg
    17281 accacagcaa ggttcctggt gggtcatcaa gtggttctgc cgcagctgta gcctcaggac
    17341 aagttcgctt gtcacttggt tctgatactg gtggttccat ccgccaacct gctgccttca
    17401 acggaatcgt tggtctcaaa ccaacctacg gaacagtttc acgtttcggt ctcattgcct
    17461 ttggcagctc attagaccag attggacctt ttgctcctac tgttaaggaa aatgccctct
    17521 tgctcaacgc tattgccagc gaagatgcta aagactctac ttctgctcat gtccgcatcg
    17581 ccgactttac ttcaaaaatc ggccaagaca tcaagggtat gaaaatcgct ttgcctaagg
    17641 aatacctcgg tgaaggaatt aacccagagg ttaaggaaac cattcaaagt gccgctaaac
    17701 actttgaaaa acttggtgct attgtcgaag aagtcagcct tcctcactct aaatacggag
    17761 ttgccgtata ctacatcatc gcttcatcag aagcttcatc aaacttgcaa cgctttgacg
    17821 gtatccgtta cggctatcgc gcagaagatg caaccaacct tgatgaaatc tatgtaaaca
    17881 gccgaagcca aggctttggt gaagaggtaa aacgtcgtat catgctgggt actttcagtc
    17941 tttcatcagg ttactatgat gcctactaca aaaaggctgg tcaagtccgt accctcatca
    18001 ttcaagattt cgaaaaagtc ttcgcggatt acgatttgat tttgggtcca actgctccaa
    18061 gtgttgccta tgacttggat tctctcaacc atgacccagt tgccatgtac ttagccgacc
    18121 tattgaccat acctgtaaac ttggcaggac tgcctggaat ttcgattcct gctggattct
    18181 ctcaaggtct acctgtcgga ctccaattga ttggtcccaa gtactctgag gaaaccattt
    18241 accaagctgc tgctgctttt gaagcaacaa cagactacca caaacaacaa cccgtgattt
    18301 ttggaggtga caactaatga actttgaaac agtcatcgga cttgaagtcc acgtagagct
    18361 caacaccaat tcaaaaatct tctcacctac ttctgcccac tttggaaatg accaaaatgc
    18421 caacactaac gtgattgact ggtctttccc aggagttcta ccagttctca ataaaggggt
    18481 tgttgatgcc ggtatcaagg ctgctcttgc cctcaacatg gacatccaca aaaagatgca
    18541 ctttgaccgc aagaactact tctatcctga taaccccaaa gcctaccaaa tttctcaatt
    18601 tgatgaacca atcggatata atggctggat tgaagtcaaa ctagaagacg gtacgaccaa
    18661 gaaaatcggt atcgaacgtg cccacctaga ggaagacgct ggtaaaaaca cccatggtac
    18721 agatggctac tcttatgttg acctcaaccg ccaaggggtt cccttgattg agattgtatc
    18781 tgaggcagat atgcgttctc ctgaagaagc ctatgcttat ctgacagccc tcaaggaagt
    18841 tatccagtac gctggcattt ctgacgttaa gatggaggaa ggttcgatgc gtgtggatgc
    18901 caacatctcc cttcgtcctt atggtcaaga gaaattcggt accaagactg aattgaagaa
    18961 cctcaactcc ttctcaaacg ttcgcaaggg gcttgaatac gaaatccaac gtcaagctga
    19021 aatacttcgc tcaggtggtc aaattcgcca agaaacacgc cgttacgatg aagctaacaa
    19081 aacaaccatc ctcatgcgtg tcaaggaagg ggctgcagac taccgctact tcccagaacc
    19141 agacctaccc ctctttgaaa tttctgacga gtggattgag gaaatgcgga ctgagttgcc
    19201 agagtttcca aaagaacgtc gtgcgcgtta tgtatctgac cttggtttat cagactacga
    19261 tgctagtcag ttgactgcta ataaagtcac ttctgatttc tttgaaaaag ctgttgccct
    19321 aggtggtgat gccaaacaag tctctaactg gctccaaggg gaaatcgctc agttcttgaa
    19381 tgctgaaggt aaaacactgg aacaaatcga attgacacca gaaaacttgg ttgaaatgat
    19441 tgccatcatc gaagacggta ctatttcatc taagattgcc aagaaagtct ttgtccacct
    19501 agctaaaaat ggcggtggcg cgcgtgaata cgtggaaaaa gcaggtatgg ttcaaatttc
    19561 agatccagct atcttgatcc caatcatcca ccaagtcttt gccgataacg aagctgctgt
    19621 tgccgacttc aagtcaggca aacgtaacgc cgacaaggcc ttcacaggat tccttatgaa
    19681 ggcaaccaaa ggccaagcca acccacaagt tgcccttaaa ctacttgcac aggaattggc
    19741 gaagttgaaa gaaaactaga cagaacaaaa ccagccctaa ggttggtttt ttcttctcta
    19801 ccaactccca ataactattt tggctttatt tccagagtat tttatggtaa aatgaagagt
    19861 aataatattt attaaagagg taaaaacatg attgaagcaa gtaaattaaa agctggtatg
    19921 acctttgaaa cagctgacgg caaattgatt cgcgttttgg aagctagtca ccacaaacca
    19981 ggtaaaggaa acacgatcat gcgtatgaaa ttgcgtgatg tccgtactgg ttctacattt
    20041 gacacaagct accgtccaga ggaaaaattt gaacaagcta ttatcgagac tgtcccagct
    20101 caatacttgt acaaaatgga tgacacagca tacttcatga atacagaaac ttacgaccaa
    20161 tacgaaatcc ctgtagtcaa tgttgaaaac gaattgcttt acatccttga aaactctgat
    20221 gtgaaaatcc aattctacgg aactgaagtg atcggtgtca ccgttcctac tactgttgag
    20281 ttgacagttg ctgaaactca accatctatc aaaggtgcta ctgttacagg ttctggtaaa
    20341 ccagcaacga tggaaactgg acttgtcgta aacgttccag acttcatcga agcaggacaa
    20401 aaactcgtta tcaacactgc agaaggaact tacgtttctc gtgcctaatc tctagaaaga
    20461 ggtcattcta tgggaattga agaacaactt ggcgaaatcg ttatcgcccc acgtgtactt
    20521 gaaaaaatca ttgctatcgc tactgcaaag gtagagggtg ttcactcttt ttcaaacaga
    20581 tcagtgtctg ataccctttc aaaactttca ctcggccgtg gcatttatct taaaaacgtg
    20641 gacgaagaac tcacagcaga tatctatctc taccttgagt acggagtaaa agttcctaag
    20701 gtagcggttg ctatccagaa agctgtcaaa gatgccgtcc gtaatatggc tgatgtagaa
    20761 ctcgctgcta tcaatattca cgttgcaggt atcgtcccag ataaaacacc aaaaccagaa
    20821 ttgaaagatc tatttgacga ggacttcctc aatgactagt ccactattag aatctagacg
    20881 ccaactccgt aaatgcgctt ttcaagctct catgagcctt gagttcggta cggatgtcga
    20941 aactgcttgt cgtttcgcct atactcatga tcgtgaagat acggatgtac aacttccagc
    21001 ctttttgata gacctcgttt ctggtgttca agctaaaaag gaagaactag ataagcaaat
    21061 cactcagcat ttaaaagcag gttggaccat tgaacgctta acgctcgtgg agagaaacct
    21121 ccttcgcttg ggagtctttg aaatcacttc atttgacact cctcagctgg ttgctgttaa
    21181 tgaagctatc gagcttgcaa aggacttctc cgatcaaaaa tctgcccgtt ttatcaatgg
    21241 actgctcagc cagtttgtaa cagaagaaca ataaaaagaa aaagtgtttg atagatatca
    21301 aacacttttt tctttgcctc ccactatcta aaaaaatgat aatagatata attgtaaaca
    21361 aaaatccaga taggttttgc atgattgaga aagttaaaaa aactatggca gagaatcgtt
    21421 aatctcagat tgtcggtaga acgataaaca agggcaaaaa agaaaccaat cagactataa
    21481 tataataaac taattggatc tctgtgagat agtatcaaat ggctaatccc aaagatgata
    21541 gcagatagga taacatccaa atagtacttg gactagggaa agaaggtatt cataaaatac
    21601 cctctatcaa gagtctcctc aaaaacagga ccgatgatta caggcaggac aaaagataag
    21661 atagtcgata aaaaggttgg ttgtccattt gaaaaaagca cggtaaaata ctcatcatga
    21721 atattcctat gattaatcaa atgagcatag cgtgcccaaa aattaccgag aatctgataa
    21781 accacataag ttgcaaataa gtagaagaca aatgaccagt tccagctctt tttctcaaag
    21841 ataaagagca tctttttctt ttttaacctc caaattatat agaaggaaac ttcccactaa
    21901 tcccattgtt aaaataagag aatagacatc agctcctaac cctaaaatga tcgtcacata
    21961 caatccaatt gtttgtggta aataggtaga tagtaaaata ataagcaaaa atattccaaa
    22021 ttgtcttagt ttttttgtgt ttctcatcgt acttttttga aagattaccc tgctcggaag
    22081 ccgtacttcc aagcatctat ataagaatta agtgcccctt gcctcatata gggagcaaat
    22141 tctctataat ataaccatct actatatcca tcttcccaaa cagcaagacc acctgaagtt
    22201 tgctccaagt cctcagttga aagaactgta aatgtatttg tacctgtcat tgcaagtacc
    22261 ttcttaaaat agattgttgt aggctcacat ttatagtata tttctttttt tgtctatttt
    22321 atagcccatc tcctcaactg gcaatttttc gacctgaatt acatttttcc ataaaaaatg
    22381 agacctttct agtctcattt agtcattctt agtattttct aaatcgttga tagcgttctt
    22441 ccagcaactc ttctagcggt ttttgtgaaa gtctagccag ctccgtttgg agttcttttt
    22501 tgacactctt aatcagttct ttactagaaa gtcctatttc agaaatcacc ttatccacca
    22561 cgtccatttc taacagttca tgcgaagtga ttttcatcag ttctgctgct tccatggcgc
    22621 gagtaccgtc cttccataaa atggaagcaa agccttctgg actgagaatg gcatagatag
    22681 aattttccag catccagaca cggtccgcga cagctagagc cagagccccg cctgaaccac
    22741 cttcaccgat aataatggcg ataataggaa ctttcaggtc actcatttcc atgagattgc
    22801 gagcgatagc ttccccttga ccacgttctt ctgctccgac accaggataa gcacctgctg
    22861 tattaataaa ggtcacaact ggacggccaa atttctcagc ctgtttcatc aaccgcagtg
    22921 cctttcggta gccttctgga tgtggttggc caaaattccg tttgaggttg tcttgcaaac
    22981 tcttgccttt ttggatacca acaactgtta cagcttggtc tccaagccaa ccaataccac
    23041 caacaactgc accatcatca cgaaaagaac ggtcaccatg taattggata aattcatcaa
    23101 aaatgcctgt cgcaaagtcc aaggttgtca agcgactctg ctcacgcgct tctctgacta
    23161 tttttgcaat attcatctag gactccctcc atgcaatctg actaggctag caatcgtatc
    23221 tggtaagtct cttcttttga caatagcatc cacaaagcca tgttctaata ggaattctgc
    23281 cttttggaaa tcctcaggca agctttcacg aaccgtattt tcaatcacac gacgcccagc
    23341 aaaaccaacc aagctctgtg gttcagccag aatgatatcg ccttccatag cgaaagaagc
    23401 tgtcacacca ccagtcgttg gatctgtcaa aatggtcagg taaaagagac cagcatttga
    23461 atgacgttta accgccgcag agatcttagc catctgcatg agactcatga ttccttcctg
    23521 catacgggct ccaccagagg ctgtgaatag gacaactggc aatttttcga cagtcgcata
    23581 ctcaaacaaa cgagtgattt tttcacctac aaccgtaccc atagaagcca tgataaagtt
    23641 agaatccata atcccaagag ccacagtctg acctttaata agagcagttc ctgtcacaac
    23701 ggcttcatgc agacctgttt tttcacgcat agatgccagt ttcttttggt aaccagggaa
    23761 atgcaaggga tccttgcttt caatccctgt aaacaattct ttgaaggttc ccatatcaat
    23821 cgtcaaagcc aagcgttctt gggcagaaat acgaaaggta tagctacagt gcggacagat
    23881 acgttcactt cccagatcct tctgatagat ggtatgctta cagcctggac actgggaaaa
    23941 taattcatct ggaacctctg gcttagcttg aggtttttcc ctaaccgaac gattgggatt
    24001 gattcgaata tacttatctt ttttactaaa tagagccatt gattcccctt ttcggtttaa
    24061 actcttaaag tcattttatt ctttttcttg atatttaggt aagaaggttt ccatcaagaa
    24121 ggaagtatca taatccccag caatgacatt gcgatctgaa atgaggtcaa gctggaaatc
    24181 tgcattggtc tgcactcctt caatctctaa ttcatagagg gcacgttgca ttttcatcaa
    24241 ggcgtcaaaa cgattttcgc cgtgtactat gattttggca atcatactat cataataagg
    24301 cggaatggta taacctggat aaactgctga atccacgcgc aagccaactc caccacttgg
    24361 cagatagaga ttagtaatct tacctggact tggagcaaag ttaaaggctg ggttttctgc
    24421 attgatacga cactcgatgg catgaccgcg taggacaata tcttcttgct taacagacaa
    24481 aggctgacct gccgcaatgc aaatctgttc cttaacgata tcaacacctg aaacaaactc
    24541 tgttactgga tgttctacct gaacacgagt attcatctcc atgaaataga aattgctact
    24601 tgcttcatca agaagaaatt caatggttcc tgcattctca tagccaacaa actctgccgc
    24661 tcgaacagca gcagcaccta tttcatgacg cagcgttttt ccgattgcaa tcgagggact
    24721 ttcttccaaa accttttggt tattcctttg aagagaacaa tcccgctcac ccaagtgaat
    24781 cacatgtcca tgctcatcac ctaggatttg aacctcaatg tgccgagctg gatagataac
    24841 ccgttctatg tacatggcac cattgccata attggccttg gcctcactag aggcagtttc
    24901 aaaggcagaa acgaggtcat ctggtttttc aaccttacga atccctttac cacctccacc
    24961 tgctgaagcc ttgagcataa caggatagcc aattttttca gcaacaatca aagcttcttc
    25021 agagttatgc acttctccat ctgaacctgg tataacaggc acacctgctt taatcatctg
    25081 agcacgcgca ttgatcttat cccccatcat atccataaca tgaccagatg gaccgataaa
    25141 cttgatacct acttcttcac acatggtcgc aaatttggaa ttttcactga gaaatccaaa
    25201 accagggtga atagcttctg cctcagtcaa gactgcagct gatagaactg cattaatatt
    25261 gagataagac tctgttgcct tgccaggacc aatacaaact gcttcatctg ccaaaagcgt
    25321 atgaagagct tccttatcag cagttgaata aaccgctacc gtcgcaatcc ccaattcacg
    25381 tgccgcacgg ataatacgaa ccgcaatttc accacgattg gcaattaaaa tttttcgaaa
    25441 catggagaac ctccttagtt cccaattgca aaagtaagga taccactggc tgcaagcttg
    25501 ccatccactt cagcctttgc ttcaaccaca gctatggtgc cacgacgttt tacaaaagtc
    25561 gctgtcataa ccaattggtc gcctggtaca acttgcttct tgaacttaac cttgtccata
    25621 ccagcgtaaa agaccagttt tcctttattt tcaggttttg ataactccaa cacaccagca
    25681 gtttgcgcca aggcttccat aatcagaaca cctggcataa ctgggtattg aggaaagtgg
    25741 ccgttaaaga aaggttcgtt aatggtcaca tttttgatag caacaatggt atcctcgctc
    25801 acttccaaga cacggtccac tagaagcata ggataacggt ggggaagagc ttctttgatt
    25861 ccttgaatat cgatcatttg atacgtacca atcctttacc aaactcaacc atttcttcgt
    25921 tagagacgag aatttccgtt accacaccat ccttaggagc tgggatttca ttcatgactt
    25981 tcatggcttc gataattacc aatgtttgac cttttttgac actatcacca actgtaacga
    26041 aggcaggttt atctggtcca gcagccaagt aaaccactcc aacaagtgga ctctctacaa
    26101 gatttccctc actagccaca cttgcttcag ctggagctgg aacttcttct gctacagtct
    26161 ctgctggagc agatgtagga gctactggac tcggtgttgc tagaacgggt gctggagcga
    26221 cttgagttgc aacttcaggc acaggtctcg cttcattctt gctaaactgc aactcatccg
    26281 tcccattttt ataagaaaat tctctcaaac ttgactggtc aaattgagtc atcaagtctt
    26341 taatatcgtt taaattcata cttatctatt ctcccaacgt ttgaaagcaa gaactgcatt
    26401 gtggcctcca aaaccaaaag tatttgaaat agcgtatgga atttctttct ccaagccttg
    26461 tccataaacg acattagctt cgatataatc tgatacttca cttgtcccag ctgtcattgg
    26521 tacaaagtta tgacgcatag cttcgatggt gacgatagct tctactgcac ccgcagcccc
    26581 cagcaaatgt cctgtaaaag acttggttga tgatacaggt acttccttac caagaacagc
    26641 tacgatagca ccactttctc ctttttcatt ggcaggagtt gacgttccgt gagcattgac
    26701 ataggctact tgctctggag aaatctcagc ttcttccaag gctagtttga tggccttgat
    26761 agctccctga ccttctggat gtggagaagt catgtggtag gcatcacaag tatttccgta
    26821 accaaccact tcagccagga tagtagctcc acgtttttca gcgtgttcaa gactttctag
    26881 aaccaacatc cctgaacctt cacccataac aaacccattg cgatccttat caaatgggat
    26941 cgaagcacga gttggatcct ctgtagtaga gagagctgtt aaggcttgga aaccagcgat
    27001 ggcaaaaggt gtgatagaag cttctgttcc tcccaccaac atcacatctt ggaaaccaaa
    27061 cttaatggag cggaaggcat ccccaatcgc atcatttgat gaagagcagg cagtattgat
    27121 agatttacaa acaccgtttg caccaaaacg catggctaca ttcccagaag ccatatttgg
    27181 taaagctttt ggaagagtca ttggtttgac acgtttgggt cctttttcat gaaggcgaag
    27241 tacctgatct tcaatttcct tgattccacc aataccagat gcaacgataa caccaaaacg
    27301 atccctatta agagcctcta catcaagatt ggcatgattt acagcctctt gggctgcata
    27361 caaggcatat aaagaatagt tatcaaaacg gttggtatct ttttttacaa agtatttatc
    27421 gaacggaaaa tcttggattt ctgccgcatt atgcacatca aagtcactat gatcaaattt
    27481 tgtaatgcca ccaatgccga ttttcccagt tgctaaacta ttccaaaatt cttctggtgt
    27541 atttccgatt ggagatgtta ctccataacc tgttaccact actcgattta gtttcattct
    27601 tttcacctct agctttcgct acatacttaa gccaccatca atggcaacca cttgaccagt
    27661 tagataatct tggcctgcta aaaatactgt caaatctgca acctgctctg cctgcccaaa
    27721 ttctttcatc ggaatctgag ctagtgtagc ttccttaatc ttatctgata agatagctgt
    27781 catatcagac tcaatcattc ctggagcaat cacattgact cgtatattcc gactagcgac
    27841 ctcgcgtgcc acagacttgg taaagccaat caagccagcc ttagaagcag catagttagc
    27901 ttgaccaata ttccccatca aaccaacaac actagacata ttaatgatag caccttctct
    27961 ggctttcatc atcggtttca agactgattg tgtcatatta aaggcaccag tcagattgac
    28021 cttgagcact ttttcaaaat ctgcttctgt catcttgagc ataagagtat cttgggtaat
    28081 ccctgcattg ttgaccaaaa catctactga acccagttct gcaatagctt gatcaatcat
    28141 acgcttagcg tctgcaaaat ctgatacatc tcctgaaatg ggaaccacct tgataccata
    28201 gtttgaaaac tcagcgagca attcttctga gattgcccca cgactgttta agacaatgtt
    28261 ggctcctgct tgagcaaact tgtgggcgat ggcaagacca attccacgac tcgaacctgt
    28321 aataaagata tttttatgtt ctagtttcat ttttttcctt tcaaaacttc tacttatttt
    28381 agtctatttt tctaaaagtg ctactaaact cgcttgatct tccacatgag ctaagtgagc
    28441 agtttgatca atttttttaa caaaacctga caagactttc cccggtccaa tctcgataaa
    28501 gttgcttatg cctgcttctt gcatgacccc aatactttca tagaaacgaa cgggttcctt
    28561 gacctgacgc gtcaagagct gagcaatgtc ctctttttgc atcacagcag cttctgtatt
    28621 gccgactagg ggacaagtaa aatctgaaaa acttacctga gctagagttt cagctagttt
    28681 ctggctagca ggctcaagga gagcggtgtg aaagggccct gacaccttaa gaggaatcaa
    28741 gcgtttggca cctgcttctt gcaaaagttc aaccgctcga tcaactgcaa ccacttctcc
    28801 agcaatgacg atttgtgcag gtgtgttata gttggctgga gtaaccactc caagttcaga
    28861 agctttttga caggcttctt caatgacctc tactggcgta ttgagaactg ctaccatctt
    28921 gccagagtca gcaggagccg cttcttccat ataggctcca cgcttagcta ccaaggcaac
    28981 cgcatcttca aaatccaagg cgccgcttgc caccaaggca gagtattctc caagagacaa
    29041 accagcaacc atatcaggct gatagccctt ttcttgcaat aaacggtaga tagcaaccga
    29101 agtcgctaga atggctggtt gcgtatagcg ggtctgattg agtttgtctt cttccgtatc
    29161 gatgagataa cgtaaatcat aaccgagcac ctgactcgct cgatcaatcg tttctttgac
    29221 aatcggatac tgatcataga aatcccgtcc catccctaga tactgggcac cttgaccagc
    29281 aaataaaaag gctgttttag tcatttctta caactcctgc ccagcgagag gcttcttctt
    29341 gaattttctt agcggctccg taatacaaat cttttaggat ttcttcagct gtttcttctt
    29401 tagaaacaag ccctgcgatt tgacctgcca tgacagagcc accatccaca tcaccgtgaa
    29461 caactgcttt ggctagggca cctgctccca tttgttcaaa gatttctaaa tcaggatctt
    29521 cctgcttaaa ggcatctttt tcagccagtt caaaatctct agtcaactga tttttaatag
    29581 cacgaacagc atgaccaaag tgctgagctg aaatcgtagt atcaatatcc cttgctttta
    29641 aaattttctc cttgtagttt ggatgggcat tcgactcttt tgcaactaca aaccgtgtcc
    29701 ccacctgtac agcctctgca cctagcataa agccagccgc agcaccttca ccatccgcaa
    29761 ttcctcctgc agcaataaca ggaatagata tagctgtggc tacctgtcgc accaaggtca
    29821 tggttgttaa tttaccgata tgccccccag cttccattcc ttctgcaata acagcgtctg
    29881 caccgatttt ttccatgcgt ttagctaaag cgacactagg aacaacagga ataacgatta
    29941 tcccagcttc atggaaacgt tccatatact tgcttggatt tcctgctcct gttgtgacaa
    30001 ctttaacacc ttcttcaata acgagatcca cgatatcttc cacaaaggga gataagagca
    30061 tgatgttgac cccaaagggt ttatcagtca atgatttgat tttatcaata ttggccttga
    30121 caacttcttt cggggcattt cccccaccga taattcctaa tcctccagcc ttggaaacag
    30181 cccctgccaa atcaccatca gcaacccagg ccatccctcc ttggaaaata ggatagtcaa
    30241 tcttcaataa ttctgtaata cgcgttttca tagtgcctcc aaccttcctt gcttacgtaa
    30301 tagttcgatt tcaccataat ttgacagtca aactattacc taaacaagag ggagtgggtt
    30361 tctccctact ccttctacta atattctgct tattttgctt gctcttcaac gtaagcaacc
    30421 aagtcaccaa ctgttttcaa gtcattttct gcttcgattt ggatatcaaa agcatcttcg
    30481 atttctgaga ttacttggaa caagtccaat gaatctgcgt ccaaatcatc aaaagttgat
    30541 tcaagtgtta cttctgatgc gtcttttcca agttcttcaa cgataatttc ttgtactttt
    30601 tcaaatactg ccatgatagg actcctttaa aataaatagt ttttttataa caatgtgttc
    30661 accacatgat tacctaaatt gtaagaatga gcgtgcccca ggtcaagcct ccaccgaagc
    30721 ctgatagaag aacagtctgg ctaccatcta aagggatgag accttgttct acacactctg
    30781 aaagtaaaat cgggatactg gctgcactgg tattgccata ttccatcata ttggctggaa
    30841 gtttggctcg gtcaacacca atttttctag ccatcttatc caaaatacgg tcattggctt
    30901 gatgaagtag cagataatcc aagtctgtca cctctatagg agattcatca atagtctgct
    30961 tgatagactt ggctacatct cgaatggcaa aatcaaagac tgtgcgtcca tccatcttca
    31021 aaaacgaatc tgcactttct tgatctgaaa atggagaatg caaacctgaa tgcccataag
    31081 ttaaacactc gctgcgactt ccatcgctat tgagactctc agctaagaaa tgctcttgct
    31141 cgctagcttc taacaagaca ccaccagcac catctccaaa caacacagct gttgatcgat
    31201 ccgaccaatc gactgcctta gagagggttt cactaccaat caccaagcct ttttgaaagc
    31261 gaccagaagc gataaacttt tcagcagttg aaagagcaaa tacaaatcca ctgcaagccg
    31321 cggttaagtc aaaagcaaag gctttattag cgccaatatt agcttgaaca cgagcagctg
    31381 tagagggcat catcgaatct ggagtaatgg tagctaggat gataaaatcc agttcttttc
    31441 ctgttattcc agcttttgcc atcagtttct tagcaacctc tgtagccaaa tcactggtag
    31501 attctgttct tgaaatatgc ctttgtcgta ttcccgttcg acttgaaatc cactcatcat
    31561 tggtatccat aatctgagcc aagtcgtgat ttgtaaccac ttgctctggc acataatgag
    31621 caacctgact tatttttgca aaagccatta tttcaaatcc tccaaaaatt ggtaaagatt
    31681 agtcaagcct ttacccatga cagcaatttc ttcctcgctc atgccatcaa taattttttc
    31741 taccatggcc ttgtggaagc gtttatgcag tctatgaatc aagcgaccct tctttgtcaa
    31801 atgcagatgc accacacgac gatcctgttc tgaccgaact cgctcaatgt agcccttacg
    31861 ctctaaattg ttcaaacttg tcgtaacagt tccaagagtt accatcaact cttttgacac
    31921 ttgacttgga gtcacatctg gagccttacc gatgacatca atcgtatgca tttctttgat
    31981 ggagatatcc ttaaaacgac tacctctcaa gttcacttcc tcaattacaa ggacattgtt
    32041 aaatatagat gttaaatatt cattgattcg ttggtagtcc atttttcata tccctccttc
    32101 ttcaaaaaac ttttacaatc aaaacatttg acagaaagaa ttatatcaaa attcaaagaa
    32161 tgatgcaagt attttttatt ttcctgtaaa tttaggtctt cttctctccg aatgagctcg
    32221 cactccttct ttgaaatcct ctgtttgagc taaggatttc tgtaggttca gttctaaagt
    32281 agcgtaaccc tgccagtctt taaactggct ctcccaaacc aacttcttaa tggcagcata
    32341 ggaattactt gaagcacgtc ttaatttttt aagaagctgt tctctcgtct tttcaagttt
    32401 ttcagcttca gaaacgcggt aaaccaaccc ccattctagg gctttttctg ccgttaaagc
    32461 ctctcctgtc atagctaatt gagcagcacg cgtcacaccg atactgcggc tcaagagatg
    32521 aattccccct gcatctggag ccaaaccaac accaacaaag gcttggataa acttagcctt
    32581 atccgtcgcc aaacagaaat ctgccgcaac agccatattc gctgcggcac ctgcaacagc
    32641 accgtcaact tccattaaaa caggtttggc tatttgcttg attttataag aaatcgtatt
    32701 gaccaactct gcgatttttg tcaatgatgg aatatcatcc tcatccactg cccgcttcat
    32761 ctctaccaaa tctcccccaa ctgagaagac ctttccattg gcattgatta agataaaatg
    32821 cacagctgga ttttcttctg ccaaagtcag agcttctaaa atctcctcac acatgggaat
    32881 atgaaaacca tttgcgacct caggacggtt caaggtaagg attgccaagt cctcttcaag
    32941 ctgataaata atgtgttcca tcagggctcc tttttatttt ataagcagtt tatactcttc
    33001 gaaaatctct ttaaaccgcg tcagcttcca tctgcaacct caaaacagta ttttgagctg
    33061 acttcggcta gcttcctagt ttgctctttg attttcattg agtgttaaat tatttcactg
    33121 tcaaagtata tcttttttag gagcagaaag caagaaaaaa tcgactgaaa gtgtctcagc
    33181 cgataagaaa ggctcgcttt aggctagaaa gcatcttatt ttcttcattg aaaaaagcct
    33241 ttctttctgc tataatcgta taaaatactt actttaggag ttcttatgaa agttgttaaa
    33301 tttggaggta gttctcttgc ctctgctagt caattagaaa aagttttaaa catcgtcaaa
    33361 agcgattcag agcgtcgttt tgtagtcgtt tctgcgcctg gtaaacgcaa tgctgaagat
    33421 actaaggtta cggatgccct gattaaatac taccgcgact atgttgcggg taacgatatt
    33481 agcaagagcc aaagctggat tatcgaccgc tatgctgcta tggttagtga attgggacta
    33541 aaaccagctg tgctagaaaa aatttctaaa agcattcacg ccttggccac tcttcctatt
    33601 gaagaaaatg aatttctcta cgatactttc ctagcagccg gtgaaaataa caatgccaaa
    33661 ttgattgctg cctactttaa ccaaaatggt atcgatgcac gctatatgca ccctagagaa
    33721 gctgggattg tggtcacaag tgaacctggt cacgctcgca tcattccatc aagttatgac
    33781 aagattgaag aattgacaaa caccaatgaa gtccttgtca ttcctggttt ctttggtgtc
    33841 actaaggaaa atcaaatctg tactttctca cgtggaggtt ctgatattac aggttctatc
    33901 attgctgctg gtgtcaaagc tgacctctat gaaaacttta cggacgttga tggtatcttt
    33961 gcagcccacc ctggtattat ccaccaacca cactcgattc ctgagttgac ctaccgtgaa
    34021 atgcgcgagt tggcctatgc aggcttctca gtccttcatg acgaggctct tcttcctgcc
    34081 taccgtggaa aaattcctct ggttatcaag aataccaaca accctgacca tccaggtact
    34141 cgtatcgttc taaaacacag taatgatgaa tttccagttg tgggaattgc tggtgactca
    34201 ggctttgtca gcattaacat gtcgaaatac ctcatgaacc gtgaggttgg atttggccgc
    34261 aaggttctgc aaatcctgga agaacttaac atcggttggg aacatatgcc aacaggtatc
    34321 gacgatcttt ctatcattct ccgttctcgc caactaactc ccatcaagga agaagaaatc
    34381 ctgcgtcagt tggttcaaaa ggctaaagta gatcatgcag aaatcgaaca cgacctttct
    34441 atcattatga ttgttggtga aaaaatgaag agccacatcg gagtgactgc tactgcgaca
    34501 cgcgctctat ctgaaaacaa aatcaacatc cagatgatgt ctcaaggttc tagtgaagtt
    34561 tctattatgt ttgttgtcaa taaagaccaa gagaaagcag caattaaagc cctctacaat
    34621 gccttttttg gagaaagtaa ggaagactaa gcatggccca atcacttaac aaaacagtac
    34681 tcctcagtac gacaggcact tcctacctct ctatcgctgg gaaagttggg aaattccttg
    34741 tcggagatca ggctttggaa ttttacccag atgtcaatgt cgaacaattt atccagattc
    34801 cttggagcca tatcaatcag attggagcca atgtcactgg atgcaaaatc agccgccact
    34861 tcgaagtctt tacagacaaa ggaaaattcc tctttgcttc aaaagactca ggtgccattc
    34921 tcaaaattgc acgcgaaaaa ctaggcaatg acaaggtcgt caaacttccg accctgattc
    34981 agacaattag ccaaaaattt aaaaatctat ttgcaaaaaa gtagaaactt tagtataatc
    35041 atagcaacgg ataagtaggt tatcttcttc tttcagaaag tctgcgggta ctgcgagcag
    35101 ataggaggga taggtgaaat tctaccgtta gtaacaatta catacacaat caagtgcaca
    35161 cctgtgaagt tggatggaac cgtggccctg ccactccaac gttttgtcag gcgtgctttt
    35221 ttcataaagg agttcttatg ttagatatca aacgtattcg tacagatttt gaagctgtcg
    35281 cagaaaaatt agctacacgt ggtgtagatg ctgctgtctt gaatgaaatg aaagaaatcg
    35341 atgctaaacg tcgtaacatc ttggtcaagg ttgaaactct caaagcagaa cgtaacacag
    35401 tttctgctga gattgcccaa gctaagcgca acaaggaaaa tacagatgac aagattgctg
    35461 ccatgcaaaa tctatctgct gaggttaaag ccttggatgc tgaattggca gaaatcgata
    35521 ctaaattgac agaatttaca acgactcttc caaatatccc agctgacagc gttcctgttg
    35581 gggctgacga agacgacaat gtggaagttc gccgttgggg tactccacgc gagtttgact
    35641 tcgaacctaa agctcactgg gatctcggtg aagaccttgg tatccttgac tgggaacgcg
    35701 gtggtaaggt aacaggcgct cgcttcctct tctataaagg cctcggtgct cgtttggaac
    35761 gtgctatcta caactttatg ttggatgaac atggaaaaga aggctatact gaagtcatca
    35821 caccttacat agtcaaccat gattctatgt ttggtactgg tcagtatcca aaatttaagg
    35881 aagatacttt tgaactcagc gataccaact ttgtcttgat tccaactgct gaagttcctc
    35941 tgacaaacta ctaccgtgat gaaatcttag acggcaaaga tcttccaatc tacttcactg
    36001 ctatgagtcc gtcattccgt tctgaggctg gttctgccgg tcgtgatacg cgtggcttga
    36061 tccgtttgca ccaattccac aaggttgaaa tggtcaaatt tgccaaacca gaagaatctt
    36121 acgaagaatt ggaaaaaatg acagccaacg ctgaaaacat tcttcaaaaa ctcaaccttc
    36181 cataccgtgt cgttgctctc tctactggag atatgggctt ctcagctgcg aagacttacg
    36241 acttggaagt gtggattcca gcacaaaaca attaccgtga aatctcaagc tgttcaaaca
    36301 cagaagattt ccaagcccgt cgtgcccaaa tccgttaccg tgatgaagca gatggcaagg
    36361 tgaaactcct tcataccttg aacggttctg gacttgcagt tggacgtaca gtggctgcaa
    36421 ttcttgaaaa ttaccaaaat gaagatggtt ctgtgaccat cccagaagca cttcgtccat
    36481 acatgggtgg agctgaagtc atcaaaccat aaaaaataag gtttagctat ttctagctag
    36541 accttttttc gtaaccaaat cagataagca cctagtacaa agaataaaat agttaggcat
    36601 ataatggttt cagccaatac caggtaatcc agaaatggaa gtttcaaaat tccctgagcc
    36661 atcttgagcg aggtcgctgt gataatggtt gggaaggtga gggctgagaa ggctggttga
    36721 aaaccttgtt ttaaaatgtt gggcagacga gttaaaacaa agaaaaagaa ggattgagaa
    36781 gccaaaatca tgacaatcaa gacccaagtc ggcaggctgg ttcctcctac tcgaactaga
    36841 gaagccaaga gtagagagaa aggagcacag tagattcctt cttgtccaag caaggctagt
    36901 gggagtggat gtttctttaa atcgctataa ataaggggat agagatagaa ggtcaagaga
    36961 aaaccaaaac tcaaggtcgc ataggcaatt tcgataatac ctaccagagg ataggtcaag
    37021 gcagccactg ctatccccac atagagaacc gtccagcttg gagtggcatg aaccctccgc
    37081 cctggacaag caaacttgat ggtaaaacca gcaatcaagg tcaaatccaa gagaaatgaa
    37141 aaccaccaaa tcccttgtgc taccaaagga agataagaga atacgcgaaa gacataggtc
    37201 gataaaatca tcccagccat aggaaaggtt gccattcctg acaaaagagg gggcttggtc
    37261 aattcttgct tggtttcttt ccaattaaag agatgcagaa ttagaaagta aatccataaa
    37321 accaaaccag tcagactaaa aagatgggat agaaccggca acgtatctaa aataagattt
    37381 ccagctcctg ccaaacctag caaacaacct gaaaatacta aggggagttt tttcatccta
    37441 acctccaata atcatgttag tttcagtata acataaaagc gcttaaatga ggatttaaaa
    37501 aaacgaagtc cgcttatttc agacttcatt ttactcagat atgaattagg cataaggttg
    37561 caattctgga ttaattggtg tattagctaa gttgttggca tagttacaga ggattgctag
    37621 gctgacacca aaaaccacat ccaaggcatt ttgttgagtg tagccagctt ctaaaaactc
    37681 agacaaggct tcatctccta cacgaccctt ggtattgata actgccaagg taaacttagc
    37741 tagggtatcc aatttaggat ctgtttcaat tggagtacga ttgcgaagag cttgaatcaa
    37801 gtcatcattc atctggattt gtttgatgga aaaggctgtg tgacctgcga cacagaaggc
    37861 acaaccattg gtcacggctg ccgtgatttg caccacttca cgctcaacgg gtgtcaggct
    37921 gttgcgacgg tggatagatg agacaatttg gtaggcttct aaaacagtcg gggcattggc
    37981 caagagaccg attaggttgg gaatatagcc attgttgtct ttttctactg tttcaagaat
    38041 ttctttcact tctgctggtg ctgactctac tgtatggata gtaaatgttg tcataagata
    38101 cctcttttct tattattgac actaatatta ttggaaaatc ttataaaatc ctgattccta
    38161 agtttatcta agataaagct ttattctctc ataagatttt cgttgttata ttagtttatc
    38221 acacttccaa tcacttgcat aatatatatt atatatcagg ctgataaaaa ttatttatag
    38281 gcaaaaaaat cacacgagct gtgtgattcc attatttgtc aaaatacttt ttagtttcag
    38341 caataacgac tggcgacaag accaagaggg caatcaagtt tggcagagcc atcaaggcgt
    38401 taacgatatc tgcgataatc cagaccatat ccaactcgat aaatcctcct aacaagacca
    38461 tgagcacaaa aaccacacgg tagagccaga taaagcgaac cccaaagagg aactcaaaac
    38521 agcgttctcc gtaatagttc caacctagaa tcgttgtaaa ggcaaaaagt acaaggaaga
    38581 tggtcaagag ggcaggccca aagtgtgaaa agactgttga gaaagctgac tgagtcaagg
    38641 caaccccatt caagtcacca ctccaaactc cagttaccaa gatggtcaaa ccagttagag
    38701 tacaaatgat gagggtatca ataaaggttc ctgtcatgga aatcaaacct tgctctactg
    38761 gttcatttgt cttggcagct gcagctgcaa taggagcaga acccagacca gattcgtttg
    38821 agaacacacc acgcgccaca ccattttgaa tagccatccg aacgctagca ccagcaaatc
    38881 cacctaccgc agcaagggga ctaaaagctg aggtaaagac taaagcgatt gtgccaggga
    38941 tttttccaat attaaagaaa ataactgtaa gagttcctaa gatataaatg atggccataa
    39001 aaggaacaac agtagttgaa accttagaaa tagacttgag tccaccaaag actgcaatcg
    39061 ctacaaagac agacaagacg agagctgtga tggctggcga aatcgtcgtt gtattttgga
    39121 tagattctgc aatcgagttg acttgggtga aggttccgat tcccaagaga gcaaccaata
    39181 ctcctgctac tgcaaacaaa acagcaagtg gtcgccactt ttctcccatc cctagaagga
    39241 tataatgcat gggacctccc gctactgcac catggtcgtc cttggtgcgg tatttgatgg
    39301 ccaagagtcc ttccgcatac ttggtagcca ttccaaagaa agccgccatc cacatccaaa
    39361 atagagctcc tggtccacca accttgatag ccgtcgcaac tcctatgata tttcctgttc
    39421 caacagttga tgccaaggct gtacacagag ctgcaaaact ggatacatca ccatgtccct
    39481 tatcctggat aaaaataagc tgaaaagcct tgggcagacg caaaacctgc aagagtccta
    39541 gccgaatagt taggtaaatc cctgttccga ccaataaaat caagaggggc ggtccccaag
    39601 caaaagcatc gattgattta agcaattcta acatttcctt ctcctatcgt ttcaacccca
    39661 aaagaaagag cacatgcaag atacatgtac tctggaatgc ttagataaat gctaaaaagc
    39721 ggtctatcct agctctgtcc ttttacctga gagtttgagc agttgcctgc cttgcccctt
    39781 cggtgccttt acggtctctc cagagttccg tccatttaca gtcatggaaa atcaaacgat
    39841 tccccacttc tattaaactt cattcggtgt tggtatttaa ttgattctaa ttttacaaaa
    39901 aatgttggct tttgtcaatg tgtttattag taaaaattag ttcaacagtt tttactttat
    39961 aaagtccaga atactgctat cctttaaaag tgacaatagt cgcaccactg cctccagcat
    40021 tttgtggggc atagccgaaa ctcttgacat gtttgtttct ttgcaagtat ttggtaactc
    40081 cttcacggat gactcctgtt ccgataccat ggatgatatc aacttgagcc atattgttaa
    40141 gcaaggcttg gtcgatgaag atatctagct cattcatggc ttcttcatag cgcttgcctc
    40201 gaagatccag tctagcttga ggtcctcgcc cagaagttcg tttcacaaca ttgacctgct
    40261 tcttcttgac tggtttttct tgctgggctt gaacaagatc aaactctttc tcttccaagg
    40321 tcatcttaat caagccaact tgggcttccc agcggccgtc cttgagttga ctggtcaagg
    40381 taccacgctg accataactg agaaccacga tatcatctcc cacctttgga gctcgttttt
    40441 tcttggcctt ttgaaggacc ttgtttttag acaagtccac tttttcagga gccaattttt
    40501 tcaacttggc cttggcttca atgatttcgt ggggcttgag ttgggattta ctgtggagat
    40561 ttttgagaat ctggtcactt tcacttaggg ccatatccac aatctcagca gcctgttcac
    40621 gcgccttgtt aagctcggtt tccttttcac gattaagctc gttgtagagt ttttttagcg
    40681 cacggttcat cttgagattt tcttgctcca cctcacggat attgtccaaa cgtttgcggc
    40741 tttccagcgt ctgctcttct aattgctcaa tgatacgatt gacgtcattg tcctgatcga
    40801 tctgctgact ggcatctcct acgataactt cagataggcc tagacgtttg gcaatttcaa
    40861 aggcattact tcggccagga acaccctgca taaagcgata ggtcgggcga agagttgcag
    40921 tatcaaactc catactggca ttttgcacaa aggctgtctc aataccgtag gccttgagtt
    40981 ctggatagtg ggtcgtcgcc atggtcttga tttgacgcag gcgaaggtcc tccagaatag
    41041 ccatggcaag ggctgctccc tcttggggat cagtaccagc ccccagctca tccaaaagta
    41101 agagtgaatg ttggttgacc ttgccaagaa tatccacgat attggtcata tggctagaga
    41161 aggtagacaa gctctgctca atagactgct catctccaat atcagcaaag atttcttcaa
    41221 aaataccaac acgacttccc ttgtctgcta aaatcggcaa tcctgactgg gccatgacct
    41281 gtgtcaagcc cagagtttta agcatgatgg tcttcccacc tgtattggga cctgtaatga
    41341 caatagctgt taaatcttga ccaaaatgga catcatttgc gacggcattt ttgaccaaag
    41401 gatggcagac atggagcagt tgaatctctt gattttctga cagctgaggc acgactgctt
    41461 gtctttcttg gataaatcga accttggcac gaatcaagtc cagatgaccg ataatccaag
    41521 cgtcattagc aatctcagcc gcatgagggc ggacacgctc agaaatttct tggagaatgc
    41581 gaagcatttc atagcgctca tctgctcgca gactagcaat ttcttcgctc agtttgacta
    41641 cctcacgtgg ttcgatatag acggtgtttc cactagcaga aatatcatga acgacacctg
    41701 caatcttatt gcggtaggtg tttttgactg gtaaaacctg acggccattt ctgctagcaa
    41761 caattccttc tgtcaacatc tgcgcttttt gcttgagcaa gtcttgtaaa acatcgcgta
    41821 cctgactctc gctatcatgt atttttcgac ggattcgcgc caatttttca ctggcaaaat
    41881 tttcaatgaa acccgcatca ttaaaggcct gaagatttcc ttgtaattgc ggaaaatcat
    41941 gtaatttctc aaaccaaagg gctaattctt ccaagctgac attttccaga ttggcgtaaa
    42001 aactttgaag ttctcggctg gcaagaagca cgcgtttcaa gagtaggaac tcctcgatat
    42061 tgagatccgc tcccatctcc aacctcttgc agactcctgc aatttcctta gttgagagaa
    42121 tagtaaaatg cggttgctcg acgaaaagag cctgcatttc cttcatctca gcaaaagcct
    42181 gtttgatttt atctgctttg gcagtcggag ccagttgtct caattgctcc aagccctgct
    42241 cggtcaacaa atgaggctca aacaaggcct tgaccttatc gaactctaat gtttctaata
    42301 ttttcttatt catctttatt tccttgtctt tgaatgtcta ggtgtggtag ctttttacat
    42361 tctgatagat tcgagtcaaa tctgtaaaca aagggctagg aaaactcctg ccctttttat
    42421 ccgattaaat ttgtcaccca gatttgtttg agccaactgg ttgttatcgg tatgctctgg
    42481 atgatgtgtt ttgcgacgat actcttttca agaggatttt gtataactgc catggggatg
    42541 gtcgccaaga ttgtcaaggc catttgcaag acaaataagg tcaccaacat ggacaagata
    42601 cctgctgaaa cttggaacaa cttaccaccc agttttttgc taggaatcaa gtgtaagaga
    42661 agaccaagca aacgaccaat gctatagaca atcccaaata caagcaagta gccgatgcct
    42721 gcataaaaga ccttatccag ctgaaagagt tgatccgatg ggaaaaagaa agtcccctga
    42781 ccttcctgcg aatttgcata agggagcaat aaatggaatt gctctccaag ccccttataa
    42841 aactggccag ccataaaagc cgatgccatg gctgaaatca ggtaataaac ctgtaagagc
    42901 aggcctctcc gatagccgat ataaaatccc caaaccaaga ccaatagaag aaggaatgaa
    42961 atcataagga atcctcaatc ttgctctgtt cttgcttaca agtcacaagc ttgtgacgga
    43021 gttcttctag ctcttgctcc ttatcgtcaa attcaatctc acggctgagc tgagttgata
    43081 aacagttgac tgccaacaaa agagcgattg tttcatcatc tgcgctaggc atttgttctt
    43141 taattgcttg gtatttttct gtcgcaacct tagcgatttc ctccataaaa aggttatcat
    43201 gttcgcttgt caaggttaac gattttttcc cgaatgtaaa tttgaatcga tttagatttg
    43261 ccataaaatt cacctcacga tattatacca aaattcgcta attttgtcag tttttacaaa
    43321 ttttactgct tttgtggtac aatagaaact atggcaagta tcacactcac accaagcgaa
    43381 aaggatattc aggcttttct tgaacactat caaaccagtc tggctcctag caagaatccc
    43441 tatatccgct actttttgaa actacctcaa gcaacggttt ctatctatac ttctggaaaa
    43501 atcttgcttc agggtgaagg ggctgaaaaa tacgccagtt tctttggcta tcaagctgta
    43561 gagcaaacca gcggacaaaa tcttccttta attgggacag atgaggtggg aaatggttcc
    43621 tactttggtg ggcttgcagt tgtggctgcc tttgtcacac ctgaccagca cgacttttta
    43681 cgaaaactcg gtgtggggga ttctaagact ctgaccgacc aaaagatccg tcagattgct
    43741 cctattctca aggaaaaaat ccagcaccag gcactccttc tctcacccag caagtacaac
    43801 gaggtcatcg gagaccgcta caatgctgtt tcggttaagg ttgccctcca taatcaggct
    43861 atctatctcc tccttcaaaa aggtgttcag cctgagaaaa ttgtgattga tgcctttacc
    43921 agtgctaaaa attatgacaa gtacttggca caagaggcca atcgtttcag caatcctatc
    43981 agcttagaaa aaaaggctga gggcaaatac ttggctgtcg cagtttcttc tgtcattgcg
    44041 cgtgatctct ttctggaaaa tcttgaaaat ctgggacgag aactgggtta tcagctccca
    44101 agtggagctg gaacagcttc tgacaaggtg gctagccaga ttttgcaagc ctatggtatg
    44161 cagggactca gcttctgcgc caaattgcac tttaaaaaca ctgaaaaagc gaaaaaacgc
    44221 ttagaaaggt aagttatgaa ttcatttaaa aatttcttaa aagagtgggg attgttcctc
    44281 ctaattctgt cattactagc tttaagtcgt atcttttttt ggagcaatgt tcgcgtagaa
    44341 ggacattcca tggatccgac cctagcggat ggcgaaattc tcttcgttgt aaaacacctt
    44401 cctattgacc gttttgatat cgtggtggcc catgaggaag atggcaataa ggacatcgtc
    44461 aagcgcgtga ttggaatgcc tggcgacacc attcgttacg aaaatgataa actctacatc
    44521 aatgacaaag aaacggacga gccttatcta gcagactata tcaaacgctt caaggatgac
    44581 aaactccaaa gcacctactc aggcaagggc tttgaaggaa ataaaggaac tttctttaga
    44641 agtatcgctc aaaaagccca agccttcaca gttgatgtca actacaacac caactttagc
    44701 tttactgttc cagaaggaga ataccttctc ctcggagatg accgcttggt ttcgagcgac
    44761 agccgccacg taggtacctt caaagcaaaa gatatcacag gggaagctaa attccgcttc
    44821 tggccaatca cccgtatcgg aacattttaa gagacctaag aggccgagaa tcaccaatct
    44881 cagcctcttc ttctatcgtg agaagtgatt gtttattgac aaatactcaa cgaaaatcaa
    44941 agaacaaact aggaagctag ccgtaggctg cttaaaacag tgttttgagg ttgtggatag
    45001 aactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtggttt
    45061 gaagatattt tcgaagagta taaaataaaa acaatcccaa ctctcaccta ttcatgcaaa
    45121 ggaattttat ggaagtttat ttttcaggaa ccattgaacg gattattttt gaaaatccca
    45181 gcaattttta tcgcatcctc ctcctagaaa tcgacgatac ggacgcagag gattttgatg
    45241 attttgaaat cattgtcaca ggaaccatgg ctgatgtaat tgagggcgaa gactatactt
    45301 tttgggggca aattgtccag cactccaagt atggagaaca actgcaaatc agtcgttatg
    45361 atcgcgcaaa accaactagt aagggcttgg tcaagtactt ttcaagtagc catttcaagg
    45421 ggattggtct caagacagct cagaaaatcg tggataccta tggcgaaaat accattgacg
    45481 aaattttgca acacccagaa aagttagaag gcatcgcagg actctctgcc aaaaatcgcg
    45541 aggctttcgt ctccactctc cgtctcaact acggaacgga gatggttttg tccaaactag
    45601 ccaactacgg cattcccaac aaactagcct ttcagattca agacttttac aaggaagaaa
    45661 cccttgatgt ggttgaaaat tatccctacc agctggttga ggatatcaag ggtttgggct
    45721 ttaccattgc tgaccaacta gctgaggaac taggcatcga aagtcaggct cctgaacgct
    45781 tccgcgccgg tctagttcac agtctttttc aggcctgtat ggaaacaggg gacacctatg
    45841 ttgaagcacg ggatttgctg gaacaaaccc ttactctcct tgagtcttcc cgtcccgtgg
    45901 aactagaccc cagccaagtt gcccaagagc tctcctacct gatcgaagaa gacaaggttc
    45961 agcagattga taccaagatc tttgacaaca gcctcttttt cgctgaggaa ggcatccgca
    46021 gtcacttggt tcgtatcctt gaaaaaggaa aacagaagag tcatgattta gaaaccattc
    46081 aaaaacatat cactactatc gaggaagagc tgggaattga gtatgataac attcaaaaac
    46141 aggctatctg tgatgctatc cagaataagg tctttatcct gacaggtggg cctggtactg
    46201 gtaagacaac tgttatcaat ggaatcatcg ctgtttatgc cctgttagag ggacttgact
    46261 tcaggaagaa aagcaatctg cctattcttc ttgctgctcc aactggtcga gctgctcgtc
    46321 gcatgaatga attgacaggt ttgcctagcg cgaccataca tcgccacttg ggaatgacag
    46381 gtgacgatga taccagtcat ctggaagatt acctagatgc tgactttatc atcgtggatg
    46441 aattctctat ggtagatact tggctggcca atcaactctt ctccaatatc tcttctaaca
    46501 gtaagatcct catcgtaggt gacagtgatc agctaccttc tgtcagtcct ggacaggttc
    46561 tagcggatct gcttcatatt cctttgattc ctcagactca cttggaaaaa atttatcgac
    46621 aaagcaaaga atcaaccatc gtcaccctag ctagtcagat tcgacagggc atcttgccag
    46681 ctgatttcac ccaaaaaaaa gctgaccgtt cctactttga aattgctagt ggccatattc
    46741 ctgccaccat tgaaaaaatc ttaggtgccg ccctcagaaa tggtattcct gcccgtgata
    46801 tccaagttct ggctcctatg taccgaggga cggcagggat tgatgctatc aatcagctca
    46861 tgcaagacct gctcaatccc ccacaaaaag atcaactcag ttttgaagct cctcagtgcc
    46921 actatcgtaa gggagacaag gtcattcatt tggttaacga tgctgaaatc aatgtcttta
    46981 atggggattt aggagctatc acagacctga ttcctggtaa atacaccgaa tcgaaacaag
    47041 acgagattgt cattgatttt gatggtaatg aagtctctta cccccgtaac gaatggtaca
    47101 agattcgctt ggcctatgcc atgagtattc ataagtctca gggaagtgag ttcccagttg
    47161 tcatcctacc gattactagt gctagccgac gtatgctgga gcgaaatctc atctacacag
    47221 ccattacacg tgccaaaagc aaactcatct tactaggcga attacaagcc ttcgactatg
    47281 ctacccaaca catcggaact gcccgaaaaa cctatctgat tgaacgcttc agtgatctac
    47341 tggagaatgt tgaagaaaag caacaagctg tctctgaaac agtcacatca agtgcctctg
    47401 aacaatccta catcctaacc gaagaaaact gggacagcat tccagccatg attgggatta
    47461 cagacacaga cctcaaagag atttttggaa aatagtgcat cagaaaaacc accaattcag
    47521 gtgggttttc tgtttattaa gattatttta ctgttgctgt gcttgtaatc aattcaacag
    47581 cttttttgat agtgatatca tgtttcaaca tgtcagctga aagcaagttt tgaacttgtg
    47641 caacttccat gttgtagtct gctgccaatt gctcaacttc tttttggatt tcttcttctg
    47701 aagcatcaaa tccttcagct ttggcaactg cttcgataac aaggttagtc ttagtacgtg
    47761 actcagcttc tgcttggtat tggttgtgaa ggtcttcttg agtagttcca gtaatttgga
    47821 agtacatgtc agggttgatc ccttgacgtt gcaagttccc aaggaattca tttactgaac
    47881 ggtgaacttc ttcgtggatc atttcttctg gaagttctac gatttcagca ttttctacag
    47941 ctgtatcaat tgctgcacct tcaactgcat ctttgtaagc ttcttcttta gcagcagcca
    48001 attctttgcg gtatttttct ttcaagtcag caagtgtttc aacttcttca tcaatgtctt
    48061 ttgcaagttc atcgtcaaga gctggaactt ctttagcttt tacttcgtgg atagttgtca
    48121 cgaatttagc ttctttacct gcaaggtctt ctgcttggta gtcttctggg aatgttacga
    48181 taacatcaac ggtttcgcca gctgagtgac ctaccaattg gtcttcgaaa ccagggatga
    48241 attgacctga accaagtcca agtgagaagt tttcaccttt tccaccgtca aattcaacac
    48301 cgtcgataga accaacgaag tcgatcacaa cagtgtcgcc gtcttcagca gcagcttcct
    48361 tgataaccaa ttcagccagg ttgttgcgtt cacgttcgat acgctcttcg acatcagcgt
    48421 cagttacttc tttttctaca tcaactgata cttcaaggtt tttgtagtca cccaatttta
    48481 cttcaggttt tgtaacaact tcagcagcga taacccagtc ttgacctttt tccattgaag
    48541 ttacgtcaat ttttggttgg gcaaccactt caagaccagc ctcttttaca gctgcttcat
    48601 aagcgtttgg caaaagagcg ttcataacgt cttggtaaag tgattcttca ccaaattttt
    48661 tatcgaagat aggacgtgga aggtgacctt tacggaaacc tggaacatta agagatttct
    48721 tcactgactt gaagacacgg tccaattctg gtttgatttg gtcttgagag atagtgaaag
    48781 tcaagacacc acggtttgtt tctttgtttt caaatgatac agacattctg tcatttctcc
    48841 ttaaaatttt ttaaatacag tctattataa cattttctat aaataaaatc tagactaatg
    48901 cagacaatta tagacaacaa gcctttttcc taactaaaac actcataaag tatagacaat
    48961 tttagactac tttggatatc ttttggttag tcattttcca aaactaattt atctaatttt
    49021 taagttatat ttgacttcat cttctcagta acatgagtat aaacacttaa aatctttgtt
    49081 tcattagtat aatctacacg atccattatc gctgttatag gtacttccaa ttcagcaagc
    49141 aaacttatat gcgaatatct aaaaacatga gcagtcaata caaaatcatc tttcttaatt
    49201 tcacttttcc taaacctgtt tttcaaaaag taattgaaac aagttatcat taagggagaa
    49261 ccattatttg taaatatata atcaccttct tctaaaagaa gatattcttt taaaatttct
    49321 aacactctat cactaatacc aattactcta tatgaagcta aacttttcgg actatccaaa
    49381 aacacttcgt tattggacga ttacattata gtaaaacgaa ataagaacag gacaaatcga
    49441 tcaggacagt caaatcaatt tctaacaatg ttttagaagt agaggtgtac tattatagtt
    49501 tcaatctact atacaagacg aaattgaaga aatctttcca ttataaaacg catattatca
    49561 aggtttttaa acacctaata atatgcgttt tttcctattt taaagacttt tatccaccta
    49621 ttatacaaag ttaagtatcc atcacagttt acaattagcc ttcattacct aacccattca
    49681 ccatccttca agagagtaac ctttaagaac cgaataaata aatggcaaat ttcgttcatt
    49741 taatttaact gcactgttaa tttgattagc tccatctcct aaagtatgca ctcctactac
    49801 acggtgacta gcatcataaa ctgtagatcc actagacccc tctaaagtat caacttggta
    49861 atccaagaac atgccatcat cacttaaaac ttgtttttta tctgtataca tttgatgaac
    49921 tttaaaatta tatgatggat agcctgtgat agtcacagtt attcctgtca aatttttttg
    49981 actagtagga agacccaaag tccctaattt tgcaccaatg ggctcttcta gaattaataa
    50041 agccaagtca tattcccttg catccttaga atttaaattt ctaaattcct tcaaataacg
    50101 aacttccttt actttgatct ttccaaatgg ttcttgactt ggactaacag tcggaagaac
    50161 ataaatatca tccgcttctt tcccatagtc atgtctgtag tagttgtgag ccgctgtaat
    50221 taacacatta tctttaataa aattcgcact tcccctccct tctacattca ttccatcggc
    50281 tactccataa tacttagata aaaccatagc tgaagtcgaa tacggatact gtaaagtatt
    50341 atcaatttta atcaaatcat cattaccgat aatacttctg attgcttttg gtagtatgaa
    50401 ccatatgttg gtgaaatctc agataatgaa gaatcattag atcctggacc tttttctagt
    50461 gtctcactta cctcatattc ttcacccgta ctagaaataa cactcaaagc agatactgtc
    50521 gataactggc tagccaataa agtactcgca ataattgaaa tacccaattt tttataaaca
    50581 gttttcttca ttattgtatc ctcctaatgt aattatagcg tactattcta aatttcttaa
    50641 tctactatag aatcaagaaa tctaccacct tctttaaata ccctccatta tcacataaac
    50701 aggtaaactt ttcaattaat gactgcgctt ttcaatcacg ctagaggtac ttacttgctt
    50761 ctttgatact aagttcagcc attctttcct tgtttttctc aataaagcat gttacccaag
    50821 tgggattcgt tttggagtag tctcgcagag tccagccaat ggctttattg ataaaaaatt
    50881 ctgtttggtt caagttatga agtagaatct tttccattaa ttgagtattg gtcttctctt
    50941 ttcttaacaa ctggtggtca atagcgacac gtctcagcca gatattatct gataggctcc
    51001 attttatact caatgaaaat caaagagcaa actaggaagc tatctgcaac ctcaaaacac
    51061 tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag agtattaaga
    51121 ttatttcttc tagttcaggg tgttcataca ccaaactccc tactactcga tctaggatat
    51181 ctaccgtgtc ccaccaggat tttgtcacga ctaactgctc tagcttaggc aaatcggttt
    51241 cctttagata agactgcatt gctttcaaat agttagcagc cacatattgg tattttctag
    51301 gctccttttc ccagcaagtg tctgcaaaat cccaatcgat aatctttgtt tttttcgctt
    51361 ctggtaaata tttttataga gtttatttct ttcaggcacc gcaataccta gaaaagaaaa
    51421 ttgatggcgc atataggctt ccatgggcct tgctttttta gagtcttttg ctgcttctag
    51481 ctcctcaagt aaatctgcta aactcatcta aaactcctct tgccccacca aatggtgctg
    51541 aaaggcatag acagccgcct gggtacgatc gctgacttca agtttggcaa gaatattgga
    51601 cacgtgggtc ttgaccgtct tgagagagat aaagaggtca tctgcgatgc gctgattttc
    51661 gtagcccttg gcgatgagtt ggagaacatc tcgctcacgc gcagtcaatt cttcatgaag
    51721 ttccatatga ttgcggtggt attcaacctt cttgctaacc tcttgctcaa tggccagctc
    51781 gccagcagct accttactga cggcatgaag caattcatct gcactagaag tcttgagcat
    51841 atagcctttg gcaccagcat ctaagactgg catgattttt tcattgtcca aataagaggt
    51901 cacaatcaaa atcttggctt caggccattc tttaaggatt gctaaggtcg cgtcaatccc
    51961 attcatctca ggcatgacaa tatccatgac aatgacatct ggacgcagtt ccaaggccaa
    52021 gtcaatccct tgagacccgt tggacgcctc acccacaact tctacatcgt cttggaggtc
    52081 aaagtagctt ttcaagccca aacggaccat ttcatggtca tctactagta aaattttcat
    52141 ctttactcct ttatcattcc ttatctaaca ggggaatacg gatatcaact gccagccctt
    52201 gcttgggagc tgttaataac tgaaccgtcc ctgccatatc ttcaacccgc tccttgatat
    52261 ttcgcagtcc ataactcaag tcgtctaagc ttcctaaccg gaaaccaatc ccattgtcca
    52321 ccaccttcag ttgcaattca acatctgtct gatagaggta gacatctagg caagatgcct
    52381 gggcatggcg gagggtattg ctaatcaact cttgcaggat acggaagata tgctcctcga
    52441 ttttcttagg caatttcgtc atattctgct tgagactaac cctaagatca ctcttgtcct
    52501 caagctcttt taagagaatc tgaatccctt ctatcaagct cttctgctcc agttcaactg
    52561 gtcgcaaatg caagagcaaa acccgcaaat ccttctgggc agtttctaaa atagctgtga
    52621 cactctgcaa ctgggtctgc atcttttctc tatccaattt caaagcctgc tgactgatac
    52681 ccgataaaat aatgtgggcc gcaaacaact cctgactgac tgtatcgtgc aaatcccgag
    52741 caattcgctt ccgttccttc tcgataattt cctcttcctg atcaaggcta tgattttcag
    52801 ctttttgaag agcctctgtc aaaaggttaa gtttacctga taaggacttg aaactggcat
    52861 ccaaatctgg atctacaacc tgaactactt cttgccctgc caataaacgc ttgagattag
    52921 cctgcatttt tcttagagaa agctcttcga tccctcgcca aaacagggct aagagacagg
    52981 tcatggacat gctgaaaacc aacaataaaa agacaaattt ttctgttttt tcgacatcgt
    53041 acaaaaagat agaccagtca aaatcaagta tttccagcaa gctgtgggag aaaaaaaaga
    53101 caaataggaa ggaggtgaga gcaataatga cataggcttg ttttttcatc ctctaaccac
    53161 ctccacatca ccaatcatag tggtcaagaa aatcttgaca ctcttgttac tcttgagata
    53221 gttttttgtt tcttgatgat agtgttcatt gcggagggct cgcttgggct ggttgaaaaa
    53281 agtcaaatcc ccatagagac agttaacgct gagactgact tccacatcta caggtacgat
    53341 gattttggtc gttcctacca tctttctgag gataatgaca ttgtcatgat tggttaagat
    53401 gaccctctcc agatgaatag tgtccttgcc catgaagcga aagagattga tatcatcgaa
    53461 ttggcaagtc tggtagcttg aaaaatgatg aagatttcca aaccaacgat ttttctcctt
    53521 cttaaccgtc acaacctctt caaaaaccaa attggtctgc tctttttcct ggttcatcat
    53581 cgggtaaaga agaaagaggc tatagataac cgcaacaaaa atagctagaa tcacaaaagg
    53641 attgagcata acgatgaaaa agaagagaat ggttaccgct actaaaagaa gattatttcc
    53701 ctctttacca gtgtagtagc gaatcaaaag caaaaagagg aatagtatca gcagaaaacg
    53761 cgaaaaatgc tctgatacca tcaaaatcag agctcctgtc agaagacagg cttcgataaa
    53821 taaaaagatt ttaaattttc tcataggttc atcctctccc ttctatttta tcacaattca
    53881 aaaaagtcac ctcagtctga ggatggaaaa aaaggcgctg gttacgcctt tttcatctga
    53941 tcatttgctt cttttaattt tccataaaga agatagtcta ctttttgtag atctgctatg
    54001 gtggcacagt taagggaaca cataatcaag cgtagatctg ctttccagcc ttggacaatg
    54061 ccaagcactt cttcaactgt gtaggtttca accaattcca gaacggttcg tgacaatccc
    54121 acagccttag caccaaaaac caagcactta atcatatcca gcggattccg aacccctcca
    54181 ctaaccaaga gttcgacctt atctttccat tcttgggcat tgagaagggc ctgcatggta
    54241 gactgacccc attgattgag gtaatcacgc tggccactac gacggttttc gatataggca
    54301 aagctggtgc caccacgacc cgataggtcc actgtacgaa caccgaattc ataggctctt
    54361 tcgattgtct tggcatccat tccaaagccc acttccttga ggacaatagg aacgggaatt
    54421 tgcttgctat aatctgctag atgcgattgc cagcttctaa acttcctttc tccctcgggc
    54481 atgagtaatt cctgcatgac attgacatgc acttgcaata gaacaggatt catctcttct
    54541 acagtatgaa gtcctaactc gacaggcttg tccaatccaa tattggttcc aaggaggaga
    54601 ttgggatgac tagacttgac agaaaaagaa tcatccgttg gatttttgag ggctgcgcta
    54661 taagaacccg ttacaaataa aataccacag gattccgcca cctgagccag cttttgattg
    54721 atttctcttc ccttattact tccaccagtc atggcattga tataaaaagg aaagtcccac
    54781 tttcgaccag caaactctgt cgaaagatcg atttcatcca gattgtaaag aggcaaggaa
    54841 gaatgaatca gctccacctc atcaaagcta ttataggaac ttttctgctc aagggcatag
    54901 aggatatgct cgtccttacg atttgtcgtc atgtcctatc ctttcttgat ataagagctc
    54961 aatccccaga tcggcccaac gattttttaa ggttttggtt gattgcgcat caaaactcag
    55021 ggcgatgcca cagtcaccac caccagcacc actactcttg gcaacggcct gcaaatcttg
    55081 actggcttct ttcaactgtc taagcaaagg cgtgtaaata tctgtactca agccttctaa
    55141 aagcttgctg gctacttcta cttgctcgat aactttttcg gctttcccct gctccaaggc
    55201 ttcgaccaaa gaaaccaccg tttcttttga ggaacttaaa aaattttgat tgatattttg
    55261 cttgatttgc tggaccatgt gactcgatac agccacttcc ttggtccatc ccactaagaa
    55321 atcacattct aaagttggtt tcacttgtga gataaaaaat ccccaatcac gctccagaac
    55381 tgtcgccaag ttttcttctt ctaaccaagc agccgccttc tggcgatcaa atgactggta
    55441 gagaaccaaa tcctctgcca caatacaggc aaggtcgccc atggaaccat tgtctcctcg
    55501 cttgagcaag acagcgctag tcagcttgaa caagagattc tgatcaaccg aaagattata
    55561 gagagccagt aaagccttga caaccaagac aacgacgctg ccactagaac ctagaccaaa
    55621 ctttttccct tctcgttcca ttttgccaca gatttttagg gaaaaaggtc ttaaattctg
    55681 accgcgaaca gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca agctgtagtc
    55741 aggattaggc cttaagtcca ctgcgaaatc aaacatatct gaatagatac ggtagctgtc
    55801 agaaaaagca atctcagctc tcatatagat gggaatatcc tttatcaaag ctaactgccc
    55861 tggctctaaa atagcatatt cacctgccca atagagtttt ccgcaagttt taacagcaat
    55921 catcttgact caaatccttt gtttttgaca caatcaagcg ataacgatga ccgaaaattt
    55981 ctgataaatg ctccaagtct ttctcctgac agaagacctt aacattggga ccagcatcca
    56041 tggtaaagta gcaggcctct cctttctcac gaagctggcg aacaaagtcc atagcctcat
    56101 aagaggcatc cgtcagataa gaaaaggctg gactagcagt ctttgtcgta gcatgcatag
    56161 ccagggcatt tttctccgtt aattctccaa tcttggcaaa atcattttcc ttgagataaa
    56221 tcagcatatc ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa gtcgtcgagg
    56281 tttccacaca aagtttcatc ccgtcacggc tagagattgg ttttttcttg tcctctagca
    56341 ccaacataat catagctagt ttcaagtctg tctctacagg gtaaatttct ccactatcct
    56401 tatcccaggc tcctagtggt ccataaaaac tccgagaaga agagcctgag gcaaacttgg
    56461 cttcctgcgc taactgactt ctatccaatc caagcttgaa ataagcatta caagccttga
    56521 ccagggcgga caaaccacta gaacttgagg acaggcccgc tgccgtaggc atattgtttt
    56581 gagtatcgat acggacaaag ccctcaccag ctggacgata acggtcaata atcttactca
    56641 tcttggcatg ctcgacctca ttttgtagct gaccattgat gtaaaattcg tcagctgtta
    56701 cattggctgg taaaggcgac aaggtcgtct ctgtatacat attttccaaa gttagagaaa
    56761 tactgctagt agcaggcacc atctcttttt cttttttctt tccccaatat ttaataatag
    56821 caatatttgc gtaggaacgt actgttacag gctctctatc catgtctgaa cagctccttt
    56881 ctcttctaat ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca aggctatgat
    56941 acaacctcct agcccaccac cgctcatctt ggcacccaga gcaccatggc taagagtcgt
    57001 ttcaaccaaa aagtctgcct cagggctact gactccaatt tcttttaaat gtaaatgcgc
    57061 ttgactgagg atttgtccca gtccttcagc atctttttgt gaaattgcaa cttctgcttg
    57121 ctgggttaat tctcccaagg catgcaaaaa cggtagggca tccttgccct tattttgaac
    57181 cacttggatg gcttcacgag tatgaccata aacacccgta tcggcaatca ccaaataggc
    57241 ggataaatcc atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa taggttggtc
    57301 actgagacag gtcttagcat ccaaaccact aggattcata tgggcaatca tttcagctcg
    57361 attgaccaag atttctagta catcatgagg cagatcagcc tgatagtagt caaataccgc
    57421 acgaatggcc gctatgctga tagccgctga cgaacccatc ccccgtttct cagggatagc
    57481 cgagtcaatc tcacaacgaa tgcaggcttc tgtgatatcc aaatactcca gtgaggcata
    57541 aaccgccatg gacaaggtat cctcctcata aaggcgccaa ggactctctg caggaactac
    57601 cttacaggtc acctccacct ccaaaagagg cagggaaatg gcaggataac cgtaaacgac
    57661 cgcatgttcc cctattaaaa ttatcttact atgtgcctga ccgacaccaa ctttttttgt
    57721 cattttttcc ttttactaga cgaaaaaacg tcttattttt catacaagta ttaattcttt
    57781 cctatctatt ttattatatt ttcacaaaaa aagcgattgt ttccattcac aatcgcttct
    57841 ttcattattg aacccattcg ccattatagt tgacagaata gccatctacg gtcgtattca
    57901 ctgccaaggc acctgagcta taagcatagt accatttgcc attgacctgg aaccaacctg
    57961 tcttcatgtc tccattacct gcatttaggt agtaccaagt taaaccatct tgataccagc
    58021 cagttaccat agctcctgat gaacggaggt agtaccactt gttaccaagg tattgccatc
    58081 ctgttttcat atcaccattt ttattatcta agtaatacca tttgcctcgt acatatttcc
    58141 aacctgttgc catagaacca gaggagccaa aataatacca ttttccgttt actttttgcc
    58201 aatctgtaag catcttacct gaagcatcta ggtagtacca tggagcaggt ttgcttctat
    58261 caatgtcaat agtaacatga aaatcttgag tccaaccctt agcaacttca ccaattggta
    58321 gtggattgta agaatcatcg ccaaaatttc ctagcttatt taaataatac caattgccgt
    58381 cttcataaat ccagcctgtc tttacagcat aattattatc aaaataataa gttctctttt
    58441 cagcagatag aggatattgt tcaccgtata cttttcctgt attttcagac gtttttgcct
    58501 ctagtacttg tttatctgtt tgttctagca aagcaccatc ttgtccaaaa tagtaccact
    58561 tctcctgaag gccaatctca ttaactggtt ggttatcgaa taaattatca cgataacctg
    58621 ttccaggaat ttctaagtat tgccaaccga caaccatctc tccaatatca ccaaaatagt
    58681 aagttttacc gtctatttta tgccaataga ttgctttatg atcatctttt acataatatt
    58741 ttctattatc cttatcaaca aatcggccac ctgtggtatt cgcaaatacc gtatttgtag
    58801 ctagcaaacc aaagaaaaag actgctagta gaacttgcat catttttttc aaaagtttca
    58861 tctatatatc ctcctaaaac gattgtagca aagacccgac tgcatgtcaa tatataaaaa
    58921 ctcctcaaaa aagcagttac acaactgcaa ctgcttatct attcttgcat ggtatatcca
    58981 acaccacgca cggttttaat gtagcttttt tggcctttaa catcaagctt gctccgtaga
    59041 tagcggatat agacatctac gatatttgtc tcggtcgcac tttcatactt ccaaacactt
    59101 tccaacaatt gctcacgagt caatactttc ttgcttccca taagtgtcgc caaaaggtca
    59161 tactcacggc gggtcagagc aatcatctct tcaccacgat aaaccgtgtg atgttcaaca
    59221 tctatcctaa gattgcggta ggtccttgga actttcatca gactgcagtg ttgatcaatg
    59281 aagtcccgac ctcggaagat cgccgaaata cgcgctacca gattttcgat aaggactggc
    59341 ttataaatgt atgaaactgc aaaacgctga acaacttcca gctcttcttg caagtcttcc
    59401 caatgatcta aaatcatgat gactgaggca ggtttagttc gactcaattt ttctgcaaaa
    59461 tcctgagcca tcatatctcc cagattaacg ttcaataaca tcaaatcata gtctgtctga
    59521 agagccatgg agagggcttt ttgcccctcc tctaccagat caacccgata ctgctctttc
    59581 tggagttcca aacttaaaaa atgagctaga tttcgttctt tctcaagtaa taaaatccgt
    59641 ttccccatgg ctgacctact tatttttcgt cataccaaga gtagtggaag gttccttctt
    59701 tgtctttacg ttggtaagtg tgagcaccaa agtagtcacg ttgtgcttgg atcaagttag
    59761 ctggaaggtc agctgaacgg tagctatcaa agtaagtaat agctgctgag aaagttggca
    59821 ctggcacacc agcttgaacc gcaagagcta cgatatcacg cactgcttgt tgatacttag
    59881 cagtaacatc caagaagtac tcgtccaaaa gaaggttggc aagatctgca tcgcggttgt
    59941 aagcatctgt aatcttttgc aaaaaacgag aacggatgat acagccatca cgccagatag
    60001 atgcgatatc tgcaaatggc aagttccagt tgttttcttt agaggctaca cgcaattgag
    60061 caaatccttg tgcgtatgaa atgatttttg agaagtaaag ggcttgacgg atcttttcaa
    60121 tcaattcagc cttgtctcct tcaaagttga aggcagctgg ttttggaagc accttgctag
    60181 catatacacg ttcttctttg taagttgaaa tgtagcgtgc aaacactgac tcagtaatca
    60241 gtgacaatgg tacaccaagg tcaagagatg attggctagt ccatttacca gttcccttgt
    60301 tacctgcagc atcaaggatg tagtctacga ttggtccatc ttggccttca tcgtctttac
    60361 ggctcaagat atcagctgtg atttcgatca agtagctatc caattcaccc ttgttccact
    60421 cagtaaagat ttcagccata tcctctgcag aaagacctag caagtgttgc atcaagtcat
    60481 aactttctgc gatcaattgc atatcaccgt actcgatacc gttgtgaacc attttcacat
    60541 agtgaccagc tccatcagga ccgatataag tcacacatgg tttgccatct tctggtgctt
    60601 tagctgagat ttcttcaaga acatccgcaa ccaattcgta ggcctctttt tgtccaccag
    60661 gcatgataga aggaccttca agagcacctt tttcaccacc agaaactcca gtaccgataa
    60721 agttgatacc tgagtttgcc aattcttcat tacgacggat ggtatctttg tagaaagtat
    60781 ttccaccgtc aatcaagata tcacctttgt caaggtgtgg aagaagggct tggatagtag
    60841 catctgtacc aggtccagct tgaaccatca gcatgatacg acgaggtttt tcgattgagt
    60901 ttacaaaact ttcaacgtca tagcttggta caaaattctt ttcaggatgg caagcaatca
    60961 catcttccgt tttttcttta ctacggttgt agatagcaac tgtgtaacca cgtgattcaa
    61021 tattaagggc aaggttacga cccattacgg ccatacctac gacaccaaag ttagcttttg
    61081 tcatttgaca ctcctcttgt ttcatttgtt ttattttatc atttttactt ttgaaaagaa
    61141 agaattttgt aacgactgct tagtagtcca agtcatccgc atgaccagcg ccatttccga
    61201 caaagtagcc tgtcttacag ttaagggtaa agagataggt tccatctggc ttatagaggt
    61261 tgtaataacc attgccgtta acgatattga cacgttcaag gatatattgg tctccagtga
    61321 tatagccacg tgaacgtgaa gtcgctagaa tttgttccaa gacaccatcc gcaaaatccc
    61381 aggcagagtt attactatca tcaatagcag actgattata ggcaacacga ctggcacttc
    61441 tttgaacagc aacccctgca ctcgagagac ccatattgac ttcactgcga ctacttctag
    61501 tctcatttga actacttggt tttggctcac tagtcgtatt tgaacttgct tgacttgaac
    61561 ttgagctgct agtttgactt aaacttgagc tagaagtact tgtttgctgg ctcttaccaa
    61621 gactgatagc cttatctagc actttatcaa gctccgtatt tccagtttta atatctgtaa
    61681 atttagcatc cgatttggct ttggcattgg tatccaacac accatccaca atagctgatt
    61741 tttcaaattg tgcattgaca tcttgaatag ccttgatttg cgttgctaga ctatcatatt
    61801 tagatttggc aagcgtatgt tcacgactac cttccagctt atcaagtaaa gtcttgagtt
    61861 gattcagttt atcaaactgg ctatttttca aagccgtttt attgctatct gtgtaaaagg
    61921 cgtcataaag tgtattaaaa tcatccacat ccgattgatt ggctgtagtt gattgagaag
    61981 tttcaatttc cttggtcgaa cgagccactt gacggtagac ataataagca ctgacacaaa
    62041 taattactga tacaagcgcc aaaacggtca aaataaagcc ttttttactt ttcttttctg
    62101 agtcctcttg atccagacga gaaaggtttt gctcctcttc cacttcttca gtcatttctg
    62161 ttggattttc atcatctagc aatagaggat ccaagccttg ctcctcatcg tccagaggca
    62221 agggtagtaa gatgtcttca gaagatggaa cttcctccga agaagcttct gacttctcta
    62281 cagcctcacg catctcttga attaaatcat ccagactctg agtttcaacg aactcctctt
    62341 ttttgtattg acgagtcgca aacttatccg cctcaatttc atctctgtgt tgcttaacat
    62401 acttgtccaa aatggaatcc tcaggcaaga ctcctgcttc cacttcttca tttttacgaa
    62461 tagcttgacc aactgttagc tcttttgctt catcaaaatc aaattgcggt tcttgacctt
    62521 cttttttttg acgatttcgt ctttttttac tcatgagtat cctttctatt ttacctcttg
    62581 ccgtttgaca cgctgaccaa aatattgata tagatccact ttcaaggttc cgttgtataa
    62641 cttacgcttc ttatctgctt ggctaccata cttgctttca aaagcttcat cactagtcag
    62701 gataaatttg ctccaagttt tcagcggtgc aaatacttgc cccatctcag catagagctt
    62761 ggtcacccct gcatcatctg acaaacgttc accataaggc ggattggaaa tgattactcc
    62821 attgatttta tcggaacgta aatcctgcac gcgcatctgc ttaaaagtaa tgtctcctgc
    62881 aacaccagct acctgagcat tggccttagc aatttccacc atgcgagcat caatatcaca
    62941 gcccattata tccagctcaa gctcacggtc tactttttta gccgcttctg tgcgcacttc
    63001 ttgaatcaag cgatcgctga tccagttcca ttcctcaaat gcaaaagagc gacgaagacc
    63061 tggcgccatc tttctagcaa tcataactgc ctcaatacag aaagtccccg aaccacaggt
    63121 cggatcaatc aaaggcttgt ctggatacca gttagaaagt tgtaaaatgg ctgctgccat
    63181 attttccttg ataggagcgc cacctttttc ggtacgataa ccacgtttaa agaggctaga
    63241 cccggtcgta tcaatcatga cagttgccac atctttgaga atagagacct caatcttaaa
    63301 ctctgggcca ttctccatca gaggaacccc ttctgggcga gcatagtgtt tctgcaattt
    63361 cttgacaaca gctttcttag aaatagcctg aacactgggc tcattgtgaa gtttggactt
    63421 aacacattta gcttttgaaa tcgggaaccg agctccaagt ggtaaataat tttcccaatc
    63481 caaagcgaaa actccctgaa atagctcttc aaaagtctta gctgggaacg ttcctacgat
    63541 aattttgata cgatctgctg cccgaagcca aaggttggtt tcgataatag ctctcacgtc
    63601 tccttgaaaa cgaacacgtc cattttcaac ctgacaatcg tagcccaact ctcgcacttc
    63661 acgaccaacg acagcctcaa gccctgctgc cacagttgca attaaattaa attctttttt
    63721 catgttacag tcttgcaaga cctttctata tgtccacttt aaaaaatgag gttgagaaaa
    63781 tttctcagcc ccaacctata tgcaattttc tataagccat gttttgttcc agaagtgact
    63841 aggaccactt ccttcgataa tcatctgtct accactaaca gctctagctg atagcagtca
    63901 gaatactacg ttcgtttccg cgtactccat gccccgacca aaatttgggt tgctagcttg
    63961 aggggtttac cgcgttccac tctctctgtt tccagaaaga ctccgtcact gtggcacttt
    64021 caagcctact ctggcctatc caaggactta gccatttcaa ctgccgtaac gatttctcgt
    64081 ccctaggctt atggtttcgc ctagcacaaa cactacaggc atcacagcct gtgctagcat
    64141 ggactttcct catgagaagc aattctcctc acgcgattat ccaaaaattg cacatctcaa
    64201 ataactactt aaaaatctga gttatctaaa atttgtttac caaaaacttc tttttccaat
    64261 ctattcaggc gtttcaaaat atcaaaattc gtcatagaac ttgtaattgc cgcttcaagg
    64321 ggttctgctt gaactggtga aggtttcggt ttacgagtta attcttcctt caaatccgca
    64381 atttcctgac gaagtgactt gaccaaggca gcataggttt catagtcctt gatgacatcg
    64441 tctaaaaact cgtcaacttc tactttatta tagccacgga cttcacgtcc aaactcttgt
    64501 tcaaaaatat ctttcgctga aaaaataata cttgccatgt ctctctccat tctcgcttgc
    64561 tagtattatt atataaaaaa aggcaaacaa aaatcaaggt caaagcttca attttcggaa
    64621 aaattttcag caagttcatt taattgatca aatgttaatc tctttataaa atagtcctct
    64681 tgatttttca tcttttggta aaaataagct agttttgttt cattttcttc atcataaaaa
    64741 agataggaac tagtcgtgtt ttccagcaaa aattgctgat aatctcttaa ctgccccttg
    64801 tgttcataac gaggataagc atatttgaca aagtctacct gcttaaagcg actcagtttc
    64861 atctgattgc cttcattcca attttcccca tgggtttcaa aagcaaaaat ggtggccaac
    64921 tggaaaccgt attcggtttt catctcctga gcaacctcta aaacccaata ttcaaaaccc
    64981 aaacttcctg taaacacaag ccaagacacc ccatctgctg ccatagcctc taaatcttta
    65041 cgtatcgctt ttttaatcaa tttaagacga ggatccttat cagaaaataa acccaaatca
    65101 aaagcagaat agcctaaaac caaagctgta gccattttta accctttctg tgcaaattat
    65161 ggtataataa agtgatgtta ttgtaccaat aaggagaatt atggtcaact atccacataa
    65221 agtttcatca caaaaaagac aaacatctct ttctcaaccc aaaaatttcg caaatcgagg
    65281 aatgtctttt gaaaagatga tcaatgctac caacgactac tatttgtctc agggcttggc
    65341 tgttatacat aagaaaccaa ctcctattca aatcgtacaa gtggactatc cacaacgaag
    65401 tcgtgccaag attgttgaag cctattttcg acaagcttca acgacggact attctggcgt
    65461 ttataatgga tattacatcg actttgaagt caaggaaaca aaacaaaaac gtgcgattcc
    65521 gatgaaaaat tttcatccac atcagattca gcatatggaa caagtccttg cccaacaagg
    65581 aatctgcttt gtccttcttc acttttcttc tcagcaagaa acctacttat tgccggcatt
    65641 cgatttgatt cgcttctatc atcaagataa gggacaaaaa tcaatgccac ttgaatatat
    65701 tcgagaatat ggatatgaaa tcaaggctgg tgccttccct caaattcctt atctcaatgt
    65761 tatcaaagaa catttattag gtggtaaaac aagatgaaca aaccaacgat tctgcgccta
    65821 atcaagtatc tgagcattag cttcttaagc ttggttatcg cagccattgt cttaggcgga
    65881 ggagtttttt tctactacgt tagcaaggct cctagcctat ccgagagtaa actagttgca
    65941 acaacttcta gtaaaatcta cgacaataaa aatcaactca ttgctgactt gggttctgaa
    66001 cgccgcgtca atgcccaagc taatgatatt cccacagatt tggttaaggc aatcgtttct
    66061 atcgaagacc atcgcttctt cgaccacagg gggattgata ccatccgtat cctaggagct
    66121 ttcttgcgca atctgcaaag caattccctc caaggtggat caactctcac ccaacagttg
    66181 attaagttga cttacttttc aacttcgact tccgaccaga ctatttctcg taaggctcag
    66241 gaagcttggt tagcgattca gttagaacaa aaagcaacca agcaagaaat cttgacctac
    66301 tatataaata aggtctacat gtctaatggg aactatggaa tgcagacagc agctcaaaac
    66361 tactatggta aagacctcaa taatttaagt ttacctcagt tagccttgct ggctggaatg
    66421 cctcaggcac caaaccaata tgacccctat tcacatccag aagcagccca agaccgccga
    66481 aacttggtct tatctgaaat gaaaaatcaa ggctacatct ctgctgaaca gtatgagaaa
    66541 gcagtcaata caccaattac tgatggacta caaagtctca aatcagcaag taattaccct
    66601 gcttacatgg ataattacct caaggaagtc atcaatcaag tggaagaaga aacaggctat
    66661 aacctgctca caactgggat ggatgtctac acaaatgtag accaagaagc tcaaaaacat
    66721 ctgtgggata tttacaatac agacgaatac gttgcctatc cagacgatga attgcaagtc
    66781 gcttctacca ttgttgatgt ttctaacggt aaagtcattg cccagctagg agcacgccat
    66841 cagtcaagta atgtttcttt cggaattaac caagcagtag aaacaaaccg cgactgggga
    66901 tcaactatga aaccgatcac agactatgct cctgccttgg agtacggtgt ctacgattca
    66961 actgctgcta tcgttcacga tgagccctat aactaccctg ggacaaatac ccctgtttat
    67021 aactgggata ggggctactt tggcaacatc accttgcaat acgccctgca acaatcgcga
    67081 aacgtcccag ccgtggaaac tctaaacaag gtcggactca accgcgccaa gactttccta
    67141 aatggtctcg gaatcgacta cccaagtatt cactactcaa atgccatttc aagtaacaca
    67201 accgaatcag acaaaaaata tggagcaagt agtgaaaaga tggctgctgc ttacgctgcc
    67261 tttgcaaatg gtggaactta ctataaacca atgtatatcc ataaagtcgt ctttagtgat
    67321 gggagtgaaa aagagttctc taatgtcgga actcgtgcca tgaaggaaac gacagcctat
    67381 atgatgaccg acatgatgaa aacagtcttg acttatggaa ctggacgaaa tgcctatctt
    67441 gcttggctcc ctcaggctgg taaaacagga acctctaact atacagacga ggaaattgaa
    67501 aaccacatca agacctctca atttgtagca cctgatgaac tatttgctgg ctatacgcgt
    67561 aaatattcaa tggctgtatg gacaggctat tctaaccgtc tgacaccact tgtaggcaat
    67621 ggccttacgg tcgctgccaa agtttaccgc tctatgatga cctacctgtc tgaaggaagc
    67681 aatccagagg attggaatat accagagggg ctctacagaa atggagaatt cgtatttaaa
    67741 aatggtgctc gttctacgtg gaactcacct gctccacaac aacccccatc aactgaaagt
    67801 tcaagctcat catcagatag ttcaacttca cagtctagct caaccactcc aagcacaaat
    67861 aatagtacga ctaccaatcc taacaataat acgcaacaat caaatacaac ccctgatcaa
    67921 caaaatcaga atcctcaacc agcacaacca taacatttat cacccagatt tttctgggtg
    67981 attttgtcat agcactattg tatttatgtg cttaacaaaa gcctgagaag acatcttctc
    68041 aggctttttc tgtactataa acctcattgg aaaagataga gactgcttcc gtaatcttgt
    68101 taagaggttt tactaaatac tagtctttct tcgtttttac tacaaagaga gcagataggg
    68161 ctagactaac acttgctagg aagagggctg tgtcagattg actctcacct gttgctggca
    68221 agatttgttc aggtgtttct ggtctagcta tttcttgctt ataatctggc gtcttacctt
    68281 gattggaaac taaagagcta agtttaaact caggtttctc tacagttgga gcatctggtt
    68341 tcgtagcaga atcttttaat tggttgagat aatctgcaaa gtattccacc attctttccg
    68401 tcaagagatg gttatccgtc gcatatttca tgcttgcctg aacgctagct acttcctctt
    68461 gattgtcttt gtctgttaat ttctgagctt tagccaaagc tgcttcatag cctgacaagt
    68521 caagaggtgt ttctgctacc tgtggacgag taaagatgag ttccgctgca gattggtatt
    68581 tatcgccacc atctccgtaa gtcttagtac ctgtaaggac aattttctta gccttaattg
    68641 tcttaccaaa atcaatgtct tttggcttat tgttatctgg ccaatcagtt gcagtaaagg
    68701 tatgctcctt gccagactca tctgtcacaa caagtttcac atcacgcaag ttaccatttg
    68761 aacctgatcc acgtggaaca taacgaagtc cagtgatttc agttggttct ttcaagacca
    68821 tggttgcagg cttgcctaca tctcctccgc cccatgatgt atgccataaa ctagataagt
    68881 ttccatcaaa ggcatttgca agaccttctt gagcctgagc aggagctgta agactttcaa
    68941 agtcttctgc taccaaagcc gttttcttct gaaccaaagc attcttcaag gcttcaatct
    69001 tggcaatctc tgcacgcgct tcttccacac tgatatcatc atcggcctga ctgaggttaa
    69061 agaccgcctc tttcaaagca tccatagact ctttggtgta gttagtcatg gcaaccgttg
    69121 gcaagtagtt cttcagagca ttttctgtca acatcttacc tgttagggta atttcttcga
    69181 tttgaagatt atccatcatg aagtcgttat aaccacggaa gttggcattt ccaccagaat
    69241 caccacgagt attacttgca tttccagttg agtagatacc tacccaagta tcccctgttt
    69301 ctgcacctgt cacaaggaag gttgccttct tggctttctt agaatctgtc caagtatttg
    69361 gcaattcatg aatttccaag ttgcttgctt gagtgccacg acgacctgac tggaattctc
    69421 ccttaccgac tacaaaagaa taggtattgt ctgaacctgc ttcgtattca aaggttacac
    69481 ggtaggtctt acctgcttca aaacggaagt tttgcggaat agtttggtaa accaagttac
    69541 gacggctcac tagtccattt gtcttgagtg accaatttcc ttcgataaca tcatcgactt
    69601 ttttaccatt ccaaccacgt tgtgtatatg gatcgtgttt ttcagacaag tgagtacggt
    69661 tgtcttcgac accttcgaca ccacccacta caaatgggaa gataccctga gcaacatttt
    69721 caaagtcttg cttgaaggtg cctttacctg tatcatgctt gtctccatac atgcttgaat
    69781 tgttttcaaa ggtacgaatt tcatcaaagt aagttgcttg atcaccagct tcacgactca
    69841 atgtcagagt aacatttgag acgtccgatc ctgttgtaaa gaaggcgtac atgttttgga
    69901 agtaacttgt atcgttaact gtagcattgt tacgacgtgt attgtgggcg taggctttta
    69961 catagttgag ggcgagagac ttattggtat aagtagtcac ttctttttca ccagtattca
    70021 cagtgatact tgccttggca ttactacggt tatctacacc aacataaacg gcatacttgg
    70081 tatttggttt caagccagtt aatttctgag tgagactaac tttttctttg tttccttgaa
    70141 tacgaagcat atcgtttgcc ccttgagact tgacaatttc tgccttagaa gcatcgcctg
    70201 aaatggtcca atgtttcaag gtaccgctat taaatccttg gtcatagatg tgcatgcctt
    70261 cactccatga catttcagga ttagtttgtt tcgaacgata gagaacgtat ggttgatttg
    70321 ctagaagatc tagggtaatt ttaccatctt ttacagttag ttcttgctct tctgtcttac
    70381 cttggtcagt tagcttgtaa aggtaaacct tgctctttgc ccaatcgctt ggaagggtcc
    70441 aagttgttgc accggcctgc gtattgaagt agtacatctt ttccttatca gtagaaagtt
    70501 tcttaccatt tgcatcccag ttccaaggag tcaagtaagc tgaaccatct tggatgacac
    70561 gtccgttgag cgttactgta cgttcacggt atagtgggct attgacatca tttgacttac
    70621 gagttacaac taatttatta ttgtcagcat ctaccaactc cactcgcatt tctggagtcc
    70681 atttataagt gctaccgtta tcggtcatag tcaccggtgt accattttcc catttactta
    70741 cagtgaagtg ttggaagtac ttggtcatga cgtcatgagc aaataagttg gttacatagc
    70801 cattgtagtc acttcttcct tgccagcctt caaagtcttt catgctgtag ccacctagca
    70861 gtggatagtt ggctgcacca ccataacttc tgtagtcccc aacccaagca tctttttggt
    70921 ggttacggat aaagcgggtg atggcactgt tgataccttt attggtgtag ccaccgtagg
    70981 tcaagtcagc tgcccagtga tggaaggtag agtcgtactc accaccatgg ccccactcga
    71041 tcgcaaagcg ccagccttgt ttgttaattt ctttagcaag aacgtgggta gcccaggcac
    71101 cgttatcacc tgattgacca ttaccccaaa cgtccacata gataaagtcg agaccgtcac
    71161 caagtttttt cttcaaatct tcccaacgtg ccaaacgact atgagctagg tcataggcag
    71221 catcaatgtt gataccttga tctagccagt tccaaccata gctatagctt ccatctggat
    71281 tcttacggag aattttttca ttgaagtatt tagactcagg ataagtttct gaagcgttaa
    71341 cgtggatacc tagatgagct ccatatttct tagccttctc aattagggtc ttgaagtctt
    71401 cgacaccacc gatacgctta ccaatatcag catagttcaa gtgaccagag tcatggcctt
    71461 cgctaccata tcctttaagg agaacacctt gcccaagacc atctgtgtgg agattgattt
    71521 tcttgatacc atccaaggtc ataaggaatg gattttgtgc ttgagaacca aagttcatcg
    71581 cgatacggta agctgtgata tccttaactt tttcccaacc ttgaggattg ttcataatgc
    71641 tacgataagc aatggcacca tcttgccaat caacgttctt gtctgcattg gcatcttcag
    71701 tgataacaac cttagcactt ggaagttcct tcgtgtattc tgggaaaaca atgcccttat
    71761 aagctttttc ccattgccat tcagagctgt ggattcctac atagttggca tttccgactg
    71821 tttctttata agctgtcaaa cgagtccagt cattcgaacc accaccatag ctattttgag
    71881 agttactcca aacaccagca gcaagcttat ctgtagaaac aaatccatac atgtaaccct
    71941 tggctaggtc tttcattgga ttggttacat cgatatgatc atctccgctg acatgcgtat
    72001 tgtttgacat ggttgcccca tcaaacttag ctccagtttg atcactagaa acagagacta
    72061 aagcattgcc gaggaaacta atagaagaaa gtagttttct ttcgtcatca atcttttgac
    72121 ctggagtgac ttgattgtgg ttgacaatct tggtcacatc aaagtgcaat tgattgtcca
    72181 caacttgcaa gcgtactgtc atttccgcat tgattaagtg agcatcatcg cgaagcttca
    72241 tcaagtactc tgctgttgtc tcattgattt tcttataagt gacttcaggg gtgattcggt
    72301 ggttattgat aaagacttgg ttgaactgtt gcacctgtcc tggcaaagta tgcccgttca
    72361 agctgtattc cttgacacga gggaaggctt ggtcaatcac tgctttgagg accttagact
    72421 gaatcgtgtc ataagtcacc ttgctatcat caacttcagg acctgtttct ttttcagcag
    72481 gggtatcctc tgtttttacc ccctcttggt tatccgtttt aatgctgaca accgtacgct
    72541 catcgtcata agagcccgcc ttgagaagga tcttcttctc atttttaaga tggtcattga
    72601 ccgcagctgg tagagtcact gtgtcaaaga gattgacatc gttgttgctg gcatttagct
    72661 gaccgtctga cttgagagtg atagagagac ggtttgttga tcctgtttca ggagcagcaa
    72721 cacgactacc tctataccaa gtgctagctg ttggagattt atactcccag aaccagccat
    72781 ccttgtcata accgacaaaa acattattat tggtatcttt aaatttcaag aagacaccaa
    72841 agcgtgattt gcccttttca gaatcatctt tgaaggttaa atcaacagtt gcatttccat
    72901 tggcatcaac ggtcaagccc ttcttttcaa acagagctgg tttacctgcg ttatcatttt
    72961 gagcagttga ggatagttgg ttgtagcgga cacctttttc ttctcggata gtgactgttc
    73021 cctgttgttc ttttttctct accgtttgcc attcaggggt taccgtctta ggtgtttcag
    73081 gtttagcagc tgcaggttta tcctcttttg gtttttcttc agccggtttt tctttttcaa
    73141 gtgctaatag ttcttcttct gtcttaggtc catctgtaac ttctggagaa ccttggtctt
    73201 ctcccacctt aggcgcttca aaatcacgcc catcattctc ttttgctgtt gcaagagcag
    73261 tagctaaatc agctggtaag ttcgccgtgg aaccagactg cacgctatct gcaagaaccg
    73321 gacttgtccc aaagaatgca gctccaatca taacagaagc aacacctaat gaaaatttcc
    73381 gaatactata tttacaacgt ttttcaaata atcctttatt cataaacttc taaatccttt
    73441 catttttgag caagcgttta cattttcttt ttaaaaaata ctccttcctc tgaaagtgca
    73501 atgcttaacc ctgataaata aaaataatta tacttttaat ataacaaata ataactgaga
    73561 aagcaatagg aaacaagtaa aattaacaaa aattttctct attctgacaa aaagaggctc
    73621 caacttttgg gggtcagtac atttagaatc tttctttaca aatgtaaaaa aggattcagc
    73681 attcaagaga aatactaaat cctttcttat attttgcaac agttatttca catgttttgc
    73741 gagatcttct tgagcctttt tattagactc ttctttttct ttcatccatt tttcctgagc
    73801 tttttggtat tcatctacag tgactgcctt gtcttgaagt tccaagtatt tatacaagac
    73861 tggttcactt gtacctttat ttcctgacaa tgcaaatggt attgtaaatg gtatcatctt
    73921 agacaagatt gggcgacctg tacgagatgt agttggaata atcaaagcac tatctgtcaa
    73981 ccaagcttgg gctgcagcgt atttatcata gcgtttagca acatctgtag cctcatcacc
    74041 agcctcagtg accaattttt cgtagtcata tagatctact tttttagcag ctacattatc
    74101 ttcccctgag tcaaacccta aatatgtttt agtactttct cctacagaag gtttgataat
    74161 atcaaggtag gttgatggat cggcaaagtc tggaccccaa ccgacattat ctgataaatc
    74221 ccagtcttcg ccagcagcat tttcagcaaa atatgtaata ttgtttactt cgtctttttg
    74281 tagttgttga atatcaataa tgacattatc agctcctaaa gttgcttcca aggattgttt
    74341 catagattgg acgcgctgaa cttttgtagt tgctgtctgg tcaactggca tatccaaatg
    74401 aattgggaaa gtcacacctt ctgcttgtaa ggctgattta gctttagcaa attcagcctt
    74461 ggctttttct ggattgtaaa gaccatcctg agaatctgca agattaacat ccttccattc
    74521 atccccataa gtgaccaatt tctctttgac catatcgcca aagtttttac catctgcttg
    74581 aacaaatgtt ggtggaacaa agatattacg taagattttg cttgctccag tttgtccatt
    74641 caactgagag gcataggctg tacgatcaaa accaaaggca atagcctgac ggaaatcctt
    74701 gtttaagaga gcctttttag tcgatgcctt ttgttcgtcg ctggtcttag atgtgtattt
    74761 ataggactga cggtcaatat ttgtaccaac tagatacgta atagagtctt gttgagtata
    74821 gacaatattg tccttcatac tcttctcaag ctctgcgaaa cttgcacttg ttggatagag
    74881 acgagctgct gtaaggctac catctttaaa gttttctgca ggtttgctgg tatcttgacc
    74941 atcccagaat gacaatttaa ctttgtcaat atgcacattg tccttatccc agtagttcgg
    75001 atttttcgca aattcaacag aggatttggt cacaatggat ttcaacaaat aaggaccgtt
    75061 atacaagaga ctacttggat ccgtagcttt ggcaaaatca tctccttttg aattcaaaaa
    75121 ctcttcatta actggcgcaa gcacacccat ggttgtctta gaattccaga agctttctgg
    75181 tttgttcaaa gtgtactgaa ctgtctgttc atccagagcc ttaattccta cttgtgagaa
    75241 atctttgatt tcccctttta cataggcatc caaccctttg attgattctt gaacaaggta
    75301 aagagcatct gattttttat cagcagcata ttttagtcct gttacaaagt cttgagcttt
    75361 gactgccgcg tattcttcac cttcagaagt ataccatttt gcatccttac ggatagtata
    75421 agtgtaagtc aatccatcct tggatacaga ccaatcctca gccatagacg gcacaaagtt
    75481 cccgtagcga tcattttcta gcaaaccatc aaccacgtta ctggtaatat ttgctgtcgc
    75541 agccttagca gttgtcaaat agttgaggtt atcagggtct gtctcataaa tgtatgagaa
    75601 tgtcttctca cctttagcgc ttgaacctga tccagagcat gcagctaaag tagtcgccgc
    75661 caataatgtc acgcccgcaa gggcaaatag ttttgaactt ttcatcattt tctcctttaa
    75721 aactttctct ccattataga ctcttttcaa aaagatgtca acagaatttt cagaattttt
    75781 gggttagttt agtatattct gaaaagacca aaaaggagaa gacggtgatt gtcctctcca
    75841 gatgttagct gacaaagagc caaaataatt tattttaatt taatatactt ctgtggtaat
    75901 aaaacaatat tcaaaaatgg aatttttttc aatatatagg ttgctaggat ggataaatgc
    75961 cagcccaaaa caattccgat aacaatatga agtaaagtag agctaattcc cactttcaac
    76021 atcagaatta gaatcatact acaaattggg gaatggagga tatagacgct ctactaaaac
    76081 taaaaatatt gagaaccctt ttccaaaatc tatccaattg attctaattt ttgtcatttt
    76141 caaactcttt ttctataact tcgagcgctc gttcaatcac aacatgcata tcgtaatatg
    76201 tataatctgc taagcgtccc attgcttctc agtatagacc gcttctaaca attaattttt
    76261 tacattttta ttatactaaa tcaatctctt tcaaaaatat cacgtgtata gactttttcc
    76321 ttgacatctt ctaatgagtt atcatagcga ttagcaacaa tggcattact cagtcgtttg
    76381 aattcctcta aatcattgat aatggaactt ccaaaaaatg tactcccact ttctaaagtt
    76441 ggttcataaa taactactct tactccctta gcttttatac gtttcataat accttgaata
    76501 gaactttgac gaaaattatc gctattactc ttcatggtca atctatagat accaataata
    76561 atatcttttt ctactctctc attaaaaaca ttatgggctg aataatcata ataatctacc
    76621 atcttaagaa cctgatcggc aataaagtct ttacgtgtcg aattgctccg tactatagct
    76681 cctataagtt cttctggtac atcttcatag ttggcaagaa gttgcttggt atctttaggg
    76741 agacagtaac caccataccc gaaggaagga ttgttatagt gagagccgat tcgtggatcc
    76801 aaaccaactc catcaataat agcttgagta tctagcccct tcatctcaga ataagtatcc
    76861 agctcattaa aataagaaac acgcaaagct aggtaagtat ttgcaaaaag cttgaccgcc
    76921 tcagcttcag taaagcccat gtacaatgta tcaatatctt cttttaaagc gccttcttgg
    76981 agcaatcccg caaacgtctc agcaacactt accaagcgtt cattattttt atctgtccct
    77041 aaaataatac ggctgggata taagttatcg taaagtgctt ttgactcacg caaaaattca
    77101 ggactaaata agatattttc agtctgaaat ttctttcgag ctgactctgt ataaccaact
    77161 ggaaccgtac ttttaatgac catgatagca tctggattat atttaagcac cgtttcaatg
    77221 acagactcta cagcagaagt gtcaaagaag ttcttctttg gatcatagtt agttggagct
    77281 gcaatcacaa caaaatccgc atctttatat gcttcttttg catccaatgt agccactaaa
    77341 tttaaatcct tttctgccag atatttctct atgtagtcat cttgaatagg tgactttctt
    77401 tgattaatta actcgacctt ctcaggaata atgtccaccg ctattacttg atgatgctga
    77461 gccaataaaa ccgcaatgga taggccaaca tatcccgtac ctgttactgc tattttcata
    77521 ctttttcttc cctcctcata tatttgccta tcattctaca aattagaaaa tatatagatt
    77581 ccttcaatta attattcttt aacattattg tagaacatgt actagtatta gtaaaaagta
    77641 tacttaaaaa taagaactgg aatccataac ttggaaatat taaatcagtt tctgttaccg
    77701 catacataga ccaagctaat aataaaatca aacttttatt gtctaaatat ttttgtagtt
    77761 ttacaaataa gactgataag ataagtagcc atatgatgcc agcattactc atcaagaagg
    77821 aataaaacga atcaaaagtg aaactagtta atccccaaat aggatcccaa acaatttctt
    77881 tatcaacata ttgaccccag aatgtataac caaaaaaggt tcttgcgtat gcagctaatt
    77941 taatacgtcc agtcaggata ttatcaataa aaattgaaaa cttattatta gaaggataaa
    78001 attgaaatgc caaaactcct aaaaaagtag aaatacaaaa gaatgagtat cctatccatc
    78061 taagttcaag attttcaaca aacatataaa tatataaaag agcaaaaatt actatagata
    78121 ctagtagagc tgttctagtc tgcgtgaaaa aataaaagaa taactgaata aaaagacaaa
    78181 aagttacatg ataatatttc aaacgatctt tgattaacca aataaacata agacataagt
    78241 tagatagtac aatagtaaat ttattgggat gtataaaacc aaatgtaaat gctctgacag
    78301 tttcgtttct tcggatatta ataagaattt ctcgtttata atcaattata tacataagaa
    78361 gtgatataaa aattgatatg aacataatac ttaatgatac aataaatata atttttatta
    78421 ctcttcttaa atcataatga atcgtaccaa tcaacataaa ccaactcgta aagtaaacat
    78481 aattttgcat ttgtatacta gtataaagca gtaatgtagt aattagaatt atactaatta
    78541 taaattgtaa tgtgtacttt cttttctcaa aaatatgtaa aaaaatcaat atataaccta
    78601 aaataacaag gatattttga aatttttgag gaaacacaaa gtcaaaaact ggaatcgaag
    78661 aaactaacat ctttaaagtc aataaaacta tagcaatatc aaataatctt atagaaaatt
    78721 tattttgcgg tacattattt agatacggca ttggttattt tcctcttaca atataataat
    78781 ttcctataat tctcagctcc tataattgtt ttaacaatca tctgtacttt tctttttaaa
    78841 gttcttgttt tccaagtagc actataatga tgaatactaa tcgtccgttc cgtaagccta
    78901 acctccttga cctcctgatc ataaccacaa aagtaatcat ctggataaat tgctaatcca
    78961 tcaattattt ggaactgatt atttttttga aagttatttt ttaatagata atctgtaata
    79021 attgtattga cagttaccaa atgattgata tcaaaacttg cttgctcata atattgcacc
    79081 atatattttg ctatcttatc atctggcata caagcatata caagtcctgg atttacttca
    79141 ccaatatatt caaaacctgt aaaagatgaa tgagctaata tatcatctgg tattgttttt
    79201 aacaactcaa catccgtatc aaaatagatc ccaccatact tagataaaat tttaaaacga
    79261 gcataatccg atgcaaatgc ccatttccta gattcatatg cagacttcgc aaattgtgaa
    79321 tctgataaat caaaattatc ctcattccat tcaacaatct catagtctgg catatatttt
    79381 ttccaagaat taatacattt taagacaaca tctggtttct cacttccacc gaaccaaata
    79441 tagtggattt ttttaggaat catataatat tctcctcatt ctttaataat attaaaccga
    79501 tttagtattg atattttcca acttgaaagc aaattttctc ttagtatcat aagaccaaat
    79561 atatatataa tactataaat aacccctgaa attacaatat aaataaataa aggatagcca
    79621 acaaaaaaat ctttcataat atataacata aacgtactaa atataaatac tacaataatc
    79681 tttaaaatat ttaatctttc aaagtagctc caaccatcct ttcccaagta tattatttca
    79741 tataatacca taacagcttc tcctatagaa gttgcaatac ctgcccctag tgcagcaaat
    79801 ttgggtatca taataaaatt caaacaaata tttaaaacaa caccaataat acttgcctga
    79861 atggttacat tttctttacc tatagatact aggatattgg ttccatacat aatagagtag
    79921 ccaacaaata ttgcactaaa aatagatact tgaagtgtcg ggatagcccc taagtaattc
    79981 ctacccgcaa taaaaagaat aatttctctg gcattaatta caatatagcc aataaaatat
    80041 aaagaactta gcataataaa tgaagaactt ttgtttagta ttttctttgc ttcattatac
    80101 tttccttctt tataatattt gactaaacga ggtagtacaa ctgtccctaa agaagttact
    80161 acactgagca ctatagaacg aatttttaat gctgttgaat agtaaccaat ttctgtatca
    80221 ctagttagaa atcccatcat aacgacatct gtattcttat aaatagtcca tgatacagat
    80281 aaaaaaaata aaattaataa cggctttata tgttgcttta aattcaatct ttgagagata
    80341 ttttctagta ggaaagttct agatctaaaa aaattcaaaa taaaagaacc atgactagct
    80401 aaaactgtaa ttgccgcata taccatatag tcatcttttg ttcggacgac taaaaacatc
    80461 aaaaggaaac ctaatatttt aaaagtcaat gttctaattg aaatatacga atagtcttcc
    80521 aatgctttgt ataaccactc tattcctata atattgagag gaattgtaga tgacgtgata
    80581 ataataagct gccattcctg tctaaaacga ggaattatta ttaccatagt tgctaaaaga
    80641 agcatcacaa gaaatcctac taataaatta atgactaaca attctctgac agtctgactt
    80701 agcttctcct tatttttaat atatcctgca cagactttaa caccatataa tggcatccct
    80761 aacattgcaa atgttagggc ataatcaata attgaagaag cgaacgttac tcgtcccaac
    80821 ccatctgcca tcagaaccct tgaaacatat gggaaactga tgagtggaaa aataaaactg
    80881 gacatagtta gaattgtatt gaaaataaaa tttctagtaa tagatttttt agtcattatt
    80941 ttttcgtttc taatagagta ttataaattt ttttaatttt accatgcata ctatgaaaac
    81001 tatacttctc ttcaaccaac ttatgattat tgctccccat taaacttaca acatcgggat
    81061 tgtaacttgc ttctaaaata atattagata actgagaaat atcacccggt tgaattaacc
    81121 agccattatc ctcgtgtata atttcaggta tgccacctac aggcgttgat atgattgcta
    81181 atccagaagc catagcttcc aatattgcca tcgggagccc ctcattataa gaaggcaata
    81241 tcaaagtctg attagcttga aatagtattt ttttatctct ctgattaacc caatcatata
    81301 ttgtaatatg atcagtcaaa ttcagatttg atatcttttg acgtatgtct tcaagttctc
    81361 catctccagc cattgtcaaa tgcaaattag gatttatagc cactgcttga ttcatggcat
    81421 ctattaaatc ataggctcct tttcttttgc ccatccttcc taaaaaaaga aagttgttgc
    81481 ttgttatact tttctttttt tctacataaa aagaagtgtc tacaccattt tcaactatta
    81541 caatttttgc atttatatta atatttgaaa aaaaatcata ccaagtttgg gaaagtacaa
    81601 tcacataatc agataattct aacatttctc taactttatt ttttttatac tcaggaagtg
    81661 agtcataaaa tatttgaaat tctgctccat gaatatgcaa aatagctttt ttatttttac
    81721 ttttaagtaa tttcaaatac agtaattttc tccaacaact ccctcttgta gcagtgtgaa
    81781 tatggtatat gtcataatta ccagaatgaa ctacaaattt aagaagagca taactagaat
    81841 aggttaaccg tgttacaaga gagccatcaa taaaagattg ataagcagtt atatcaaaat
    81901 cacctgacaa taacgggcta tatgtcaaat ctctaataac agcgctcata ccacctttag
    81961 ataaatttat actaggccca atttgcaaaa cttttgtcat ctaaatttcc tttcaaagac
    82021 tatctatgta ttgtcgtata tcttctaaaa gtgcataact attagaaata tatggctttg
    82081 ttgtaaaagt ctgagctttt tgataaacag ttcctaactg ctctatatca aagcatggca
    82141 aaatataacc ttcctcacca agaactgtga tgatttgtaa ttggtgatta tccacatgtt
    82201 ctccaaactg ctctaatcgt ggaaccgcta taattttttt tcttaatttc aaagctttaa
    82261 caatactagc agtcccacca tgtgtaatta ccatactagc ttctctcatc ttctcattca
    82321 tatcaattga actcaaaaat gaattataag aaaagtattt aggtttataa tcagaagctc
    82381 caatctgagc aaacacctct tcctttatca cttctaattc aataagttga tctatttttt
    82441 ttaacaagcg attaaaaggg tgtttttgag tccctacagt tataaaaatc acctaataaa
    82501 gccccccttt ataaacagca tttgggtaga tatctagcat actctcccat tgcacataga
    82561 atctatctgc gtaacggtat agtattctac ctgttaaagt aggagtggtc acttttgcaa
    82621 aagattcaat ataaattaat ttagccccaa acatttttga aagcaaacaa aacggtatca
    82681 ttgcaagaac acctgtacag ataactactt ttgggcgtat tcttaacagt atataaagtg
    82741 atttcaagga aatccaaatc aatttaacga tccaaaaaaa ttccaaacga ttaatttgca
    82801 aaagataaaa caccttgttt atatctttct tctcagactc tcctttgtta taatcagtat
    82861 attctgtgat taaatagctg tcttgttgtc tcataatcgg ttcaagcttc attagttgct
    82921 cataatgtcc ccctgacgaa gcacaaaaac atactttttt tttatttttc attcctttac
    82981 ttcgctccat ccttcatcaa tacaacttta actgtcttca ataagatttc aatatctttc
    83041 cagattgtcc aatcatctat ataagctaca tctaacttga caacttcatc gaaattctta
    83101 atctcacttc gtccactaac ctgccataaa cctgttatac caggtttaaa acttagacga
    83161 cgtttttgtt ctggagtata gtgttcatac tcgtccactg ttggtggtcg tgtaccaacc
    83221 aaactcatat ctccctttag aacattataa aactgtggca gctcgtccaa gctagtcttc
    83281 cgtataaaac gaccaacttt cgtgatacgt gggtcatcat ccaccttaaa cattccaccc
    83341 tgcatggtat tttgttccat gagttctctt tttttgtcct cagcatctac acacatggag
    83401 cggaacttgt aaaaagtgaa gtggcgacca ttttttccaa tacgcgtctg agcaaaaata
    83461 gcagagcccc catcctttcg aatcaaaggg accagtacaa cactgactag accacatagt
    83521 atcagcccta ccaatgcacc cacgatatca ataatccgct tagcaatcac gtggctagtc
    83581 ttataaaatg ttgtagaaaa aatcacaacg tttaatcctg ccatctcacg aatttgcttg
    83641 ttacgtgcca aactacgatc aaaagcattt agattgactg ttacatcaat tcccatcgtt
    83701 tcaaactgag agacaagctc tccaatattg tatttttcac ttggaagatt gataaagact
    83761 tcatcgacca cctcatgagt cgcaaagttt actatctccc cctctgctac tacctttaaa
    83821 caatcatgct gaaaatctgg tttatctaag acactgacgg ctaccaactc cccaacaacc
    83881 tcatttgatt ctattaatct atccagtacc ttttcgacac gagaagttgc tgtaagtagg
    83941 agaatcttct tacttccttt aaagttggga taagcccgct tccaatacca cttgataaat
    84001 aggtttagca catagactaa gagagcatgt aatgtgagga agtaaatcat gcctcgtctg
    84061 gaaatactaa atcgatcctc taagaaaaaa ttagaaatac taatcgctag tgcaaagaat
    84121 aggatatatt tcaatgtctg gacaagttca atcaaatatc cccttttaaa gaaatcctgt
    84181 ccataatcac tgatataaaa gacaaaataa tggaggatat aaagtgcaat agctgttgct
    84241 gaagcaatct ccgcttctct cacagcacta agtagataag tcaataaaat aacaagaaaa
    84301 ctatggatta tggccaatga agaatttact acttttccat tcatctctat ccctcaatct
    84361 attttttatt tttcccgtaa tctccataat ttccataaga accgtatttg tttactgaag
    84421 tatcgaattt attcaacaca actcccaaaa acggcttccc tgtgtgttcc aactgttctt
    84481 ttgctttttg aatatcccgt cgatttattt cacctgcctc cgtcactaaa atagaagcat
    84541 cgcattttcg cgtaataata gccgcatcaa tcacgacacc gacaggagca gtatctacaa
    84601 tgatgtagtc aaaatattta cgcaaggttt caagcattgt agtgaaattc ttactttgaa
    84661 gaagagctgt cggattcggt gacacagagc cagcctgaat tacaaagaga ttttcgatat
    84721 tggtatcaca aagcccttgt gataggtctg tagttcctga taaaaattct gtcaggcctg
    84781 taatcttatc ccttgcttta aagacaccta acataacaga attgcgaata tctccatcaa
    84841 tcagcagcgt tttgtaacct gcacgcgcaa aagcccaagc gatattggtg gaagtcgttg
    84901 attttccttc tcctagtttc acagaagtga tagaaaatac tttcaaacca tctccactta
    84961 actgtaggtt catgcacaaa gagttataat attcctctgc cttttttaca aaatccaatt
    85021 ttgcctgtga gatttctaat gttggcataa cttcctccta tttcattttg tccaaatctg
    85081 gaacgagccc taaaagtgga atttgcagta catcttcaac atcttcagga cgtttcacac
    85141 gggtgtcgaa caactcaatc aaaagaacag caattactgt tacaactgct cctccaagaa
    85201 aaccaaacaa ggaattgcgt cgaacatttg gagaagaagg agtcgtagct ggtcgcgctt
    85261 cttcaagtgt cgttacatca gatactcgcg ttacagcgac gatcctttct acagcaactt
    85321 ctcgtagaga attagcgata cgactggctt cctctggctg tttatccttg acagagattg
    85381 agacgatacg agtgtcagtt ggtacagtca cttgaacttt gctagctaac gtttttgctg
    85441 gcatgtccaa cttcaaattt gtcgctactt tttccaatgc atcctgcgaa aggataatct
    85501 cacggtagtc ttttaccaga taagatcctg cctgcaaatc ctgatttgtc agccccgact
    85561 tgtctccttg attgcgattc actacgtaaa ttcgcgtggt actcgtatat tctggcttaa
    85621 caataaaagt gctatatgca aaagcccccg cacctgtcac aagtgccact aataaaatca
    85681 ttagcttgcg tttccacaag gttttaaata attgaaatac atcgatttct atcgtgtttt
    85741 gttctttcat catttctcct aaattagttg atccattata atttttcgag gattgtctat
    85801 aaaaagttcc tgagccttcg cttctccgta tttttgggta acaaagtcat atgcttctgc
    85861 catatgagga ggtctgccgt ctagattgtg catgtcactt gcaatgacat gaaccaaatt
    85921 ctgctctaaa aaatactgag ctcttttttt catgaattta taacgttctc caaaaagttt
    85981 tggtttgagg acatgtgaac tatttacttg cgtgtaacag cccatatcaa tcagttctcg
    86041 aacgcgtttt tcattatttc caagagcatc atagcgctca atgtgggcaa tgactggagt
    86101 aattcccaac atcaagatct tgctcaaggc gctatgaata tcgcgataag gagtgttcat
    86161 actaaactct atcaaggcat aacgactatc attgagggtc ggaatccgct tttttcccag
    86221 cttatccaga acatctggtg tgtagtaaat ttcagccccg taagcaatga ctaaatcatc
    86281 tgctacttct tttgcaattt cccgaacctg aagaaagctt tctgctatct tctcttccgg
    86341 agtttcaaac atacccttgc gacggtgaga ggtagagaca atggttcgca ccccctgcct
    86401 gtaggattct gccaagagag ccttgctttc ctctcttgac ttgggaccgt catctacatc
    86461 aaaaacgata tgcgaatgga tgtctatcat ttcatctacc ctccatcaca tcctgtatag
    86521 ctgctttaac tacagctaaa ctactatcat ctatttccat catatagagg ttactgtctg
    86581 gcattgcata agaaggaaga tccatccgac ctgtcccttt taaatcttga gaatttactt
    86641 tataattacc tccactttcc aactgagtat tcactaaatc tatcatagtc tcaatcggca
    86701 tatttgtttg gatagaatct tgcaagctat taatgatcgt actataattt ttcagtactt
    86761 cggttgacgt taatttttga aggatagcca caatcacctt ttgttggttg cgaccacggt
    86821 cacggtctcc atcggctagt gagtagcgtt cacgtacaaa acctagagcc tgctcagagt
    86881 ctagatggac attccctact gggaaatgga acttcccatg tagagctgaa aactcttgat
    86941 cattatgaac atctacccct cccaataagt caatcatttt caagaaagaa gtgaagttca
    87001 atagcacata gtaattgata tccactccat agaggttttc taaggtgtga atggacgaat
    87061 caactccata aatgcccgca tgggttaatt tatctttttg attatttcca ccatctgcga
    87121 ttggtacata ggcatcacgt gacgttgtgg tcaagaggat tttcttggta tcacgattga
    87181 cagtcatcag gatattgaca tctgatcgcg acaccgaact aataggtcca taggtgtcaa
    87241 ttccactaac atagatattg aaagactgat tcttagacgt cttaggagct tctacttttt
    87301 tagtgaatcc cttggtataa atcttcttta tcttcgatgc gtagtctgga tactctaact
    87361 cgatgatatt ttcaaagaca ctatttagga caatggcctt agtctcccct gcaatcaaac
    87421 tcttgtaagc aaccaagtaa gacgaactct ggtcgaccgt caaatcggta ttctgacttg
    87481 acttgatatc agctagtagt ttttgaatat tttcattatc agtcccagtc ggtgctgtca
    87541 cactcgtcag ttgcgtaaca ttttcgatct cactatctgc taaaacagcg acactgagcg
    87601 aatattctga gtaattagaa gtcgcattta aacgattggt cagtccaaca aactgctgta
    87661 ctgcaaagag cgacactgag ctgacaagga tagagaacac caacagaaaa atagtaaatt
    87721 tttcagcttt tttatagata atcaagagta gccctaccaa ggcaactagt aggactaacg
    87781 cagttaccac tagattaaga tatctaaaag caaggatatt gtacttaaag attaagaaca
    87841 ataaaaaaca aactaacaat aaataaatag tcaacaaaac tatattaaca cttcgcttca
    87901 ctttctgtga acgtgatttt ttaaaacgtc tactcatgat taacacctat acattgaaca
    87961 tcttacgatt atatcacttt tttacggtaa tgtctacacc tttttttcac tatctgcatc
    88021 tttaagtatc ttagtagact tcccgcaaaa caaaaatata gtaaaatgaa ataagaacat
    88081 gacaaatcga tcgggacagt caaatcgatt tctaacaatg ttttagaagc agatgtgtac
    88141 tattctagtt tcaatctact atagtacaca atg
//
LOCUS       DBEJZJ010000004        84515 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000004 DBEJZJ010000000
VERSION     DBEJZJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 84515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.04"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL3R8_000318"
     CDS             371..598
                     /locus_tag="ACL3R8_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313265.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL3R8_000319"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL3R8_000319"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR1313266.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4797..5249
                     /locus_tag="ACL3R8_000320"
     CDS             4797..5249
                     /locus_tag="ACL3R8_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR1313267.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5268..6605
                     /locus_tag="ACL3R8_000321"
     CDS             5268..6605
                     /locus_tag="ACL3R8_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313268.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6684..7568
                     /locus_tag="ACL3R8_000322"
     CDS             6684..7568
                     /locus_tag="ACL3R8_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313269.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7568..8401
                     /locus_tag="ACL3R8_000323"
     CDS             7568..8401
                     /locus_tag="ACL3R8_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313270.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8419..10512
                     /gene="nanB"
                     /locus_tag="ACL3R8_000324"
     CDS             8419..10512
                     /gene="nanB"
                     /locus_tag="ACL3R8_000324"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR1313271.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSSSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10524..11627
                     /locus_tag="ACL3R8_000325"
     CDS             10524..11627
                     /locus_tag="ACL3R8_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR1313272.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11801..12499
                     /locus_tag="ACL3R8_000326"
     CDS             11801..12499
                     /locus_tag="ACL3R8_000326"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR1313273.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12518..14035
                     /locus_tag="ACL3R8_000327"
     CDS             12518..14035
                     /locus_tag="ACL3R8_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1313274.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTSGRGEEVDSKEISESADSTSNIADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14160..15488
                     /locus_tag="ACL3R8_000328"
     CDS             14160..15488
                     /locus_tag="ACL3R8_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313275.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15740..16606
                     /locus_tag="ACL3R8_000329"
     CDS             15740..16606
                     /locus_tag="ACL3R8_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313276.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16622..17461
                     /locus_tag="ACL3R8_000330"
     CDS             16622..17461
                     /locus_tag="ACL3R8_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313277.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17734..18186
                     /locus_tag="ACL3R8_000331"
     CDS             17734..18186
                     /locus_tag="ACL3R8_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR1313278.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18283..18627
                     /locus_tag="ACL3R8_000332"
     CDS             18283..18627
                     /locus_tag="ACL3R8_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313279.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            18637..18831
                     /locus_tag="ACL3R8_000333"
     CDS             18637..18831
                     /locus_tag="ACL3R8_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313280.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRNILASALSSL
                     YIHYISIDRKRKKSKRKKKK"
     gene            18914..19558
                     /locus_tag="ACL3R8_000334"
     CDS             18914..19558
                     /locus_tag="ACL3R8_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR1313281.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19727..20644
                     /locus_tag="ACL3R8_000335"
     CDS             19727..20644
                     /locus_tag="ACL3R8_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR1313282.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKDKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20662..21546
                     /locus_tag="ACL3R8_000336"
     CDS             20662..21546
                     /locus_tag="ACL3R8_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR1313283.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21562..22413)
                     /locus_tag="ACL3R8_000337"
     CDS             complement(21562..22413)
                     /locus_tag="ACL3R8_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR1313284.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDGNCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22613..24670
                     /gene="pbp2b"
                     /locus_tag="ACL3R8_000338"
     CDS             22613..24670
                     /gene="pbp2b"
                     /locus_tag="ACL3R8_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR1313285.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24681..25277
                     /gene="recR"
                     /locus_tag="ACL3R8_000339"
     CDS             24681..25277
                     /gene="recR"
                     /locus_tag="ACL3R8_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR1313286.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25453..26496
                     /locus_tag="ACL3R8_000340"
     CDS             25453..26496
                     /locus_tag="ACL3R8_000340"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR1313287.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26580..27953
                     /gene="murF"
                     /locus_tag="ACL3R8_000341"
     CDS             26580..27953
                     /gene="murF"
                     /locus_tag="ACL3R8_000341"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR1313288.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAYLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGNQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            27940..28551
                     /locus_tag="ACL3R8_000342"
     CDS             27940..28551
                     /locus_tag="ACL3R8_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR1313289.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEGSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDINRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPVLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28642..29346
                     /locus_tag="ACL3R8_000343"
     CDS             28642..29346
                     /locus_tag="ACL3R8_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR1313290.1"
                     /translation="MNLWDIFFTTQATKPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIVKEA"
     gene            29565..30938
                     /gene="ftsA"
                     /locus_tag="ACL3R8_000344"
     CDS             29565..30938
                     /gene="ftsA"
                     /locus_tag="ACL3R8_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR1313291.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30955..32214
                     /gene="ftsZ"
                     /locus_tag="ACL3R8_000345"
     CDS             30955..32214
                     /gene="ftsZ"
                     /locus_tag="ACL3R8_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR1313292.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32219..32890
                     /locus_tag="ACL3R8_000346"
     CDS             32219..32890
                     /locus_tag="ACL3R8_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR1313293.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYIGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32900..33439
                     /locus_tag="ACL3R8_000347"
     CDS             32900..33439
                     /locus_tag="ACL3R8_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR1313294.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33439..33702
                     /locus_tag="ACL3R8_000348"
     CDS             33439..33702
                     /locus_tag="ACL3R8_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR1313295.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33699..34484
                     /locus_tag="ACL3R8_000349"
     CDS             33699..34484
                     /locus_tag="ACL3R8_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR1313296.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34493..35281
                     /gene="divIVA"
                     /locus_tag="ACL3R8_000350"
     CDS             34493..35281
                     /gene="divIVA"
                     /locus_tag="ACL3R8_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR1313297.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35629..38421
                     /gene="ileS"
                     /locus_tag="ACL3R8_000351"
     CDS             35629..38421
                     /gene="ileS"
                     /locus_tag="ACL3R8_000351"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR1313298.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            38824..39209
                     /locus_tag="ACL3R8_000352"
                     /pseudo
     CDS             38824..39209
                     /locus_tag="ACL3R8_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            39744..40436
                     /locus_tag="ACL3R8_000353"
     CDS             39744..40436
                     /locus_tag="ACL3R8_000353"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR1313299.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40489..42900
                     /locus_tag="ACL3R8_000354"
     CDS             40489..42900
                     /locus_tag="ACL3R8_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR1313300.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            43150..43851
                     /locus_tag="ACL3R8_000355"
     CDS             43150..43851
                     /locus_tag="ACL3R8_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313301.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43853..46561
                     /locus_tag="ACL3R8_000356"
     CDS             43853..46561
                     /locus_tag="ACL3R8_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1313302.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVVAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46657..47148)
                     /gene="tpx"
                     /locus_tag="ACL3R8_000357"
     CDS             complement(46657..47148)
                     /gene="tpx"
                     /locus_tag="ACL3R8_000357"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR1313303.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47271..48200)
                     /gene="psaA"
                     /locus_tag="ACL3R8_000358"
     CDS             complement(47271..48200)
                     /gene="psaA"
                     /locus_tag="ACL3R8_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR1313304.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEANLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48232..49080)
                     /locus_tag="ACL3R8_000359"
     CDS             complement(48232..49080)
                     /locus_tag="ACL3R8_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR1313305.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49077..49799)
                     /locus_tag="ACL3R8_000360"
     CDS             complement(49077..49799)
                     /locus_tag="ACL3R8_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR1313306.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50090..51982
                     /gene="pepO"
                     /locus_tag="ACL3R8_000361"
     CDS             50090..51982
                     /gene="pepO"
                     /locus_tag="ACL3R8_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR1313307.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52104..52733)
                     /locus_tag="ACL3R8_000362"
     CDS             complement(52104..52733)
                     /locus_tag="ACL3R8_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR1313308.1"
                     /translation="MKIYKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53727..55949
                     /locus_tag="ACL3R8_000363"
     CDS             53727..55949
                     /locus_tag="ACL3R8_000363"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR1313309.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRFLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            55979..56422
                     /gene="dtd"
                     /locus_tag="ACL3R8_000364"
     CDS             55979..56422
                     /gene="dtd"
                     /locus_tag="ACL3R8_000364"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR1313310.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(56689..56874)
                     /locus_tag="ACL3R8_000365"
     CDS             complement(56689..56874)
                     /locus_tag="ACL3R8_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313311.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(56893..57306)
                     /locus_tag="ACL3R8_000366"
     CDS             complement(56893..57306)
                     /locus_tag="ACL3R8_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313312.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(57437..58144)
                     /locus_tag="ACL3R8_000367"
     CDS             complement(57437..58144)
                     /locus_tag="ACL3R8_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGR1313313.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGL
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(58263..58913)
                     /locus_tag="ACL3R8_000368"
     CDS             complement(58263..58913)
                     /locus_tag="ACL3R8_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR1313314.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMVIAKQLYVEKIN"
     gene            59025..59867
                     /locus_tag="ACL3R8_000369"
     CDS             59025..59867
                     /locus_tag="ACL3R8_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1313315.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQLHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            59943..60380
                     /locus_tag="ACL3R8_000370"
     CDS             59943..60380
                     /locus_tag="ACL3R8_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR1313316.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            60449..60751
                     /locus_tag="ACL3R8_000371"
     CDS             60449..60751
                     /locus_tag="ACL3R8_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313317.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSFISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(60842..61915)
                     /locus_tag="ACL3R8_000372"
     CDS             complement(60842..61915)
                     /locus_tag="ACL3R8_000372"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR1313318.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPSQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPK
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            62071..62748
                     /locus_tag="ACL3R8_000373"
     CDS             62071..62748
                     /locus_tag="ACL3R8_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1313319.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            62741..63715
                     /locus_tag="ACL3R8_000374"
     CDS             62741..63715
                     /locus_tag="ACL3R8_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR1313320.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(63764..65707)
                     /gene="thrS"
                     /locus_tag="ACL3R8_000375"
     CDS             complement(63764..65707)
                     /gene="thrS"
                     /locus_tag="ACL3R8_000375"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR1313321.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(65765..66088)
                     /locus_tag="ACL3R8_000376"
                     /pseudo
     CDS             complement(65765..66088)
                     /locus_tag="ACL3R8_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(66345..66708)
                     /locus_tag="ACL3R8_000377"
                     /pseudo
     CDS             complement(66345..66708)
                     /locus_tag="ACL3R8_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            66945..67574
                     /locus_tag="ACL3R8_000378"
     CDS             66945..67574
                     /locus_tag="ACL3R8_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1313322.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            67715..67984
                     /gene="rpsO"
                     /locus_tag="ACL3R8_000379"
     CDS             67715..67984
                     /gene="rpsO"
                     /locus_tag="ACL3R8_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR1313323.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            68797..69411
                     /locus_tag="ACL3R8_000380"
     CDS             68797..69411
                     /locus_tag="ACL3R8_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR1313324.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(69704..70453)
                     /locus_tag="ACL3R8_000381"
     CDS             complement(69704..70453)
                     /locus_tag="ACL3R8_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR1313325.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            70586..72922
                     /locus_tag="ACL3R8_000382"
     CDS             70586..72922
                     /locus_tag="ACL3R8_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR1313326.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            73024..73701
                     /locus_tag="ACL3R8_000383"
     CDS             73024..73701
                     /locus_tag="ACL3R8_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR1313327.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            73688..74485
                     /locus_tag="ACL3R8_000384"
     CDS             73688..74485
                     /locus_tag="ACL3R8_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR1313328.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            74502..75605
                     /locus_tag="ACL3R8_000385"
     CDS             74502..75605
                     /locus_tag="ACL3R8_000385"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR1313329.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            75861..76880
                     /gene="galE"
                     /locus_tag="ACL3R8_000386"
     CDS             75861..76880
                     /gene="galE"
                     /locus_tag="ACL3R8_000386"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR1313330.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            76882..77847
                     /locus_tag="ACL3R8_000387"
     CDS             76882..77847
                     /locus_tag="ACL3R8_000387"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1313331.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAAHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(77898..78104)
                     /locus_tag="ACL3R8_000388"
     CDS             complement(77898..78104)
                     /locus_tag="ACL3R8_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR1313332.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            78155..78631
                     /locus_tag="ACL3R8_000389"
     CDS             78155..78631
                     /locus_tag="ACL3R8_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR1313333.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSELESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            78640..79311
                     /gene="cmk"
                     /locus_tag="ACL3R8_000390"
     CDS             78640..79311
                     /gene="cmk"
                     /locus_tag="ACL3R8_000390"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR1313334.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            79442..79780
                     /locus_tag="ACL3R8_000391"
     CDS             79442..79780
                     /locus_tag="ACL3R8_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR1313335.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            79783..80412
                     /locus_tag="ACL3R8_000392"
     CDS             79783..80412
                     /locus_tag="ACL3R8_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR1313336.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            80652..81803
                     /locus_tag="ACL3R8_000393"
     CDS             80652..81803
                     /locus_tag="ACL3R8_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1313337.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            82116..82865
                     /gene="truA"
                     /locus_tag="ACL3R8_000394"
     CDS             82116..82865
                     /gene="truA"
                     /locus_tag="ACL3R8_000394"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR1313338.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRKLAGPTAAPNGLYLKEIRYEE"
     gene            82855..83628
                     /locus_tag="ACL3R8_000395"
     CDS             82855..83628
                     /locus_tag="ACL3R8_000395"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR1313339.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            83606..84067
                     /locus_tag="ACL3R8_000396"
     CDS             83606..84067
                     /locus_tag="ACL3R8_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1313340.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            84292..84500
                     /locus_tag="ACL3R8_000397"
                     /pseudo
     CDS             84292..84500
                     /locus_tag="ACL3R8_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        25397 a        15311 c        18831 g        24976 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 agggagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tccatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacacttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacaag aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtatagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaatt attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatatgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga
     4261 aatatagagt atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta
     4321 gccaaagagt ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga
     4381 gcagcttata aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa
     4441 gggcgacttc cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac
     4501 ttatttattc tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact
     4561 taatgaaaat caaagaagaa actagcaagc tagtagcaga ttgcccaaaa caccgctttg
     4621 aggttgtaga taagactgac ctatataatc caaggtgaag cgactgtggt ttgaagagat
     4681 tttcaaagag tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga
     4741 cagaagaatg gggaacttgg ataggaaaaa tagattgaga aaggaggtta gaagagatga
     4801 ttattacaaa aattagccgt ttaggaactt atgtgggagt aaatccacat tttgcaacat
     4861 taatagattt tctagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg
     4921 atggtaatcg attgtttggg aattgcttta cttatctagc agatggtcaa gcaggggctt
     4981 tctttgaaac ccaccaaaaa tatttggata ttcatttagt tttggaaaac gaagaagcca
     5041 tggctgttac atcgccggaa aatgtaagcg ttacccaaga atatgatgaa gagaaagata
     5101 ttgaattata cacagggaaa gtggaacagt tggttcattt gagagctggc gaatgcctca
     5161 tcacttttcc agaagattta catcaaccca aggttcgtat aaatgatgaa cctgtgaaaa
     5221 aagttgtctt taaagttgcg atttcttaat gtagaaagag aagaacgatg aaaaaaatga
     5281 gaaagttttt atgtctagct ggaattgcgc tagcggctgt tgccttggta gcttgttcag
     5341 gaaaaaaaga agctacaact agtactgaac caccaacaga attatctggt gagattacaa
     5401 tgtggcactc ctttactcaa ggaccccgtt tagaaagtat tcaaaaatca gcagatgctt
     5461 tcatgcaaaa gcatccaaaa acgaaaatca agattgaaac attttcttgg aatgacttct
     5521 atactaaatg gactacaggt ttagcaaatg gaaatgtgcc agatatcagt acagctcttc
     5581 ctaaccaagt aatggaaatg gtcaactcag atgctttggt tccgctaaat gattctatca
     5641 agcgtattgg acaagataaa tttaacgaaa ctgccttaaa tgaagcaaaa atcggagatg
     5701 attactactc tgttcctctt tattcacatg cacaagtcat gtgggttaga acagatttgt
     5761 taaaagaaca taatattgag gttcctaaaa cttgggatca actctatgaa gcttctaaaa
     5821 aattgaaaga agctggagtt tatggcttgt ctgttccgtt tggaacaaat gacttaatgg
     5881 caacacgttt cttgaacttc tacgtacgta gtggtggagg aagcctctta acaaaagatc
     5941 ttaaagcaga cttgacaagc caacttgctc aagatggtat taaatactgg gttaaattgt
     6001 ataaagaaat ctcacctcaa gattctttga actttaatgt ccttcaacaa gctaccttgt
     6061 tctatcaagg aaaaacagca tttgacttta actctggctt ccatatcgga ggaattaatg
     6121 ccaacagtcc tcaattgatt gattcgattg atgcttatcc tattccaaaa atcaaagagt
     6181 ctgataaaga ccaaggaatt gaaacctcaa acattccaat ggttgtttgg aaaaattcaa
     6241 aacatccaga agttgctaaa gcattcttag aagcacttta taatgaagaa gactacgtta
     6301 aattccttga ttcaactcca gtaggtatgt tgccaactat taaggggatt agcgattctg
     6361 cagcctataa agaaaatgaa actcgtaaga aatttaaaca tgctgaagaa gtaattactg
     6421 aagctgttaa aaaaggtact gctattggtt atgaaaatgg gccaagtgta caagctggta
     6481 tgttgactaa ccaacacatt attgaacaaa tgttccaaga tatcattaca aatggaacag
     6541 atcctatgaa agcagcaaaa gaagcagaaa aacaattaaa tgatttattt gaggctgttc
     6601 agtagatgta aaagactaga aaataggtgg gatagtgagc tgaaaagctc tagcccaatc
     6661 ttgtaaaaga agggagaagg agaatggtta aagaacgtaa tttaactcgc tggatatttg
     6721 ttttgccagc tatgattatc gtaggattac tctttgttta tccgtttttc tcgagtattt
     6781 tttatagctt taccaataag catttgatta tgcctaatta taaatttgtt ggtttggcta
     6841 actataaagc tgtgctatca gatcccaact tctttaatgc gttctttaat tcaattaagt
     6901 ggaccgtttt ctcattagtt ggtcaagttt tagtagggtt tgtattggct ttagctcttc
     6961 acagagtacg ccacttcaag aaattatata ggacattatt gattgttcct tgggcatttc
     7021 ctaccatcgt tattgccttc tcttggcagt ggattctaaa cggggtttat ggctacttac
     7081 ctaatctaat cgtaaaatta ggtttaatgg aacatacacc tgcatttttg acagatagta
     7141 catgggcatt cctatgtttg gtgtttatca acatttggtt tggagcacca atgattatgg
     7201 ttaatgtgct ttcagctttg caaacagtac cagaagaaca atttgaggct gctaagatag
     7261 atggtgcttc aagttggcag gtgttcaagt ttatcgtctt tccacatatt aaagtggttg
     7321 taggacttct agttgttttg agaactgtat ggatctttaa taactttgac attatctacc
     7381 tcattactgg tggtggacca gccaatgcta caacgacgct tccaattttt gcttacaacc
     7441 tgggctgggg aactaaattg ttgggtcgtg cttcagcagt tacagtattg ctctttatct
     7501 tcttggtggc gatttgcttt atctactttg ctatcatcag taagtgggaa aaggagggta
     7561 gaaaataatg aagaagaaat ccagtattta tttagatatt ctctcacatg tacttttagt
     7621 tggtgcgacc atcgttgcaa ttttcccatt ggtatggatt atcatatctt ctgtcaaagg
     7681 gaaaggggaa ttaactcagt atccaacacg attttggcct gaacagttta cattagatta
     7741 tttcactcat gttatcaacg atttgcactt cattgataac attcgaaaca gtttaatcat
     7801 tgccttggct acaaccctta ttgcgattat tatttctgct atggcagcct atggtattgt
     7861 tcgattcttt cctaaattgg gagcaatcat gtcgagacta ctcgtcatta cctacatttt
     7921 cccaccaatt ttgttagcaa ttccctattc aattgccatt gctaaagttg ggttaacaaa
     7981 tagtttattt ggcttgatga tggtttatct atcttttagt gttccatatg cagtttggct
     8041 cttagttgga tttttccaaa cagttccaat tggaattgaa gaagcggcta gaattgatgg
     8101 tgcaaataaa tttgttacgt tttataaagt tgtgctaccg attgtagcac caggtattgt
     8161 agcaacagct atttatacat ttatcaatgc ttggaatgaa ttcctgtatg ccttgatttt
     8221 gattaacaat acaggaaaga tgacagtagc agtagccctt cgttcactta atggttcaga
     8281 aatactagac tggggagata tgatggcagc gtctgttatt gtagttcttc catcaattat
     8341 tttcttctct atcatccaaa ataagattgc aagtggatta tcagaaggat ctgtgaagta
     8401 gacgaaagaa ggaaaaaaat gaataaaaga ggtctttatt caaaactagg aatttctgtt
     8461 gtaggcatta gtcttttaat gggagtcccc gctttgattc atgcgaatga attaaactat
     8521 ggtcaactgt ccatatctcc tatttttcaa ggaggttcat atcaactgaa caataagagt
     8581 atagatatca gccctttgtt attagataaa ttgtctggag atagtcagac agtagtaatg
     8641 aaatttaaag cagataaacc aaactctctt caagctttgt ttggcctatc taatagtaaa
     8701 gcaggcttta aaaataatta cttttcaatt ttcatgagag attctggtga gataggtgta
     8761 gaaataagag acgcccaaaa gggaataaat tatttatttt ctagaccagc ttcattatgg
     8821 ggaaagcata aaggacaggc agttgaaaat acactagtat ttgtatctga ttctaaagat
     8881 aaaacataca caatgtatgt taatggaata gaagtgttct ctgaaacagt tgatacattt
     8941 ttgccaattt caaatataaa tggtatagat aaggcaacac taggagctgt taatcgtgaa
     9001 ggtaaggaac attacctcgc aaaaggaagt attgatgaaa tcagtctatt taacaaagca
     9061 attagtgatc aggaagtttc aaatattccc ttgtcaaatc catttcagtt aattttccaa
     9121 tcaggagatt ctactcaagc taactatttt agaataccga cactatatac attaagtagt
     9181 ggaagagttc tatcaagtat tgatgcacgt tatggtggga ctcatgattc taaaagtaag
     9241 attaatattg ccacttctta tagtgatgat aatgggaaaa cgtggagtga gccaattttt
     9301 gctatgaagt ttaatgacta tgaggagcag ttagtttact ggccacgaga taataaatta
     9361 aagaatagtc aaattagtgg aagtgcttca ttcatagatt catccattgt tgaagataaa
     9421 aaatctggga aaacgatatt actagctgat gttatgcctg cgggtattgg aaataataat
     9481 gcaaataaag ccgactcagg ttttaaagaa ataaatggtc attattattt aaaactaaag
     9541 aagaatggag ataacgattt ccgttataca gttagagaaa atggtgtcgt ttatgatgaa
     9601 acaactaata aacctacaaa ttatactata aatgataagt atgaagtttt ggagggagga
     9661 aagtctttaa cagtcgaaca atattcggtt gattttgata gtagctcttt aagagaaagg
     9721 cataatggaa aacaggttcc tatgaatgtt ttctacaaag attcgttatt taaagtgact
     9781 cctactaatt atatagcaat gacaactagt cagaatagag gagagagttg ggaacaattt
     9841 aagttgttgc ctccgttctt aggagaaaaa cataatggaa cttacttgtg tcctggacaa
     9901 ggtttagcat taaaatcaag taacagattg atttttgcaa catatactag tggagaacta
     9961 acctatctca tttctgatga tagtggtcaa acatggaaga aatcctcagc ttcaattccg
    10021 tttaaaaatg caacagcaga agcacaaatg gttgaactga gagatggtgt gattagaaca
    10081 ttctttagaa ccactacagg taagatagct tatatgacta gtagagattc tggagaaaca
    10141 tggtcggaag tttcgtatat tgatggaatt caacaaactt catatggcac acaagtatct
    10201 gcaattaaat actctcaatt aattgatgga aaagaagcag tcattttgag tacaccaaat
    10261 tctagaagtg gccgtaaggg aggtcaatta gttgtcggtt tagtcaataa agaagatgat
    10321 agtattgatt ggaaatacca ctatgatatt gatttgcctt cgtatggtta tgcctattct
    10381 gcgattacag aattgccaaa tcatcacata ggtgtactgt ttgaaaaata tgattcgtgg
    10441 tcgagaaatg aattgcattt aagcaatgta gttcagtata tagatttgga aattaatgat
    10501 ttaacaaaat aaaggagaaa aacatggtta aatacggtgt tgttggagca gggtattttg
    10561 gagctgaatt ggctcgctat atgcaaaaga atgatggagc agagattact cttctctatg
    10621 atccagataa tgcagaggcg attgcagaag aattgggagc aaaagtagca agttccttag
    10681 atgagttggt ttctagcgat gaagtagatt gtgttatcgt cgcaactcca aataatcttc
    10741 ataaggaacc ggttattaag gctgcacagc atggtaaaaa tgttttctgt gaaaaaccaa
    10801 ttgcgctttc ttatcaagat tgtcgcgaga tggtagatgc gtgtaaagaa aacaatgtaa
    10861 cctttatggc aggacatatt atgaatttct ttaatggtgt tcatcatgca aaagaactca
    10921 ttaatcaagg agttatcgga gacgttctat attgtcatac agctcgtaat ggttgggaag
    10981 aacaacaacc gtcagtatca tggaaaaaaa ttcgtgaaaa atcaggtggt cacttgtatc
    11041 accacatcca tgaattggat tgcgttcaat tccttatggg gggcatgcct gaaactgtaa
    11101 ccatgacagg tggaaatgtg gcccatgaag gtgaacattt cggtgatgaa gatgatatga
    11161 tttttgtcaa tatggaattt tctaataagc gttttgcctt gttagaatgg ggttcagctt
    11221 atcgttgggg tgaacattat gtcttaatcc aaggaagcaa aggtgccatc cgcttagact
    11281 tattcaactg taaaggaact cttaagctag atgggcaaga aagctatttc ttgattcacg
    11341 aatcgcaaga agaagatgat gatcggactc gtatctatca tagtacagag atggatggag
    11401 caattgctta tggtaaacca ggtaaacgta ctccattatg gctatcatct gtcattgata
    11461 aagaaatgcg ctatctgcat gagattatgg aaggagctcc agtatcagaa gaatttgcaa
    11521 aacttttgac aggtgaagct gccctagaag caattgctac tgcagatgct tgtacccagt
    11581 ctatgtttga agatcgcaaa gtaaaattgt cagaaattgt aaaataaatt ttggtattct
    11641 cctatttata ggtcgacttg ctcctctgaa agtactttta gaggagctgt ttgactttgc
    11701 tagtttttga aactgaaatc tattatacta caaactattg aaagcgtttt aattttaagg
    11761 tataataatc tcatagaaat aaagaaaagg aggaaagagg atgccacaga ttagcaaaga
    11821 agccttgatt gagcaaatca aagatggaat catcgtttct tgtcaggctc ttcctcatga
    11881 accgctttat acagaagcgg gaggggtgat tcccttgctg gtcaaagcgg ctgagcaagg
    11941 tggagcagtc ggtatccgag caaacagtgt tcgcgatatc aaggaaatta aggaagtcac
    12001 taaacttcca atcattggga ttatcaaacg tgattatcca cctcaggaac ccttcatcac
    12061 ggctactatg aaagaagttg atgaattggc agaactggac atcgaggtga ttgctctgga
    12121 ttgtaccaag cgtgaacgct acgatggttt ggaaattcaa gagttcattc gtcaggttaa
    12181 ggagaaatat cctaatcagc ttttgatggc tgatactagt atcttcgaag aagggctagc
    12241 agctgtagaa gcaggaattg actttgtcgg aacaacctta tcaggctaca catcctacag
    12301 tccaaaagta gacggtccag attttgaatt gattaagaaa ctctgtgatg ccggtgtaga
    12361 tgtcattgca gaaggaaaaa ttcatacacc agaacaagcc aaacaaatcc ttgaatatgg
    12421 agtgcgaggc atcgttgttg gtggcgccat tactagacca aaagagatta cagaacgctt
    12481 cgttgctagt cttaaataag atgtgagggg gagttttatg tttaaagttt tacaaaaagt
    12541 tggaaaagct tttatgttac ctatagctat acttcctgca gcaggtctac ttttggggat
    12601 tggtggtgca ctttcaaacc caaccacgat agcaacttat ccaatactag acaatagtat
    12661 ttttcaatca atattccaag taatgagctc tgcaggagag gttgtattca gtaatttgtc
    12721 actacttctc tgtgtgggat tatgtattgg cttagcgaaa cgagataaag gaaccgctgc
    12781 gttagcagga gtaactggtt acttagttat gactgcaacg atcaaagctt tagtaaaact
    12841 ttttatggca gaaggatctg caattgatac tggagttatt ggagcattag ttgtcggaat
    12901 agttgccgta tatttgcaca accgatataa caatattcaa ttaccttccg ctttaggatt
    12961 ctttggaggt tcacgcttcg ttcctattgt tacatcgttc tcttctatct tgattggctt
    13021 tgtcttcttt gttatttggc cacctttcca acaacttctt gtttctacag gtggatatat
    13081 ttctcaggcg ggtccaattg gaacttttct atatggattt ttaatgagac tttctggagc
    13141 agtaggctta catcatataa tttaccctat gttttggtat actgaacttg gtggtgttga
    13201 aactgttgca ggacaaacag tggttggagc tcaaaaaata ttttttgctc aattagccga
    13261 tttggcccat tctggattat ttacagaagg aacaaggttt tttgcaggtc gtttctcaac
    13321 aatgatgttc ggtttaccgg ctgcctgttt agcgatgtac catagtgttc ctaaaaatcg
    13381 tcgtaaaaaa tacgcgggtt tgttttttgg agttgcttta acatctttta ttaccggtat
    13441 tacagaacca attgaattta tgtttctatt cgtcagtccg gttctatatg ttgttcacgc
    13501 attccttgat ggtgttagct tctttattgc agacgtctta aatatttcaa taggaaacac
    13561 attttcagga ggtgtaatcg atttcacttt atttggaatt ttgcagggga acgctaagac
    13621 gaattgggtt cttcagattc catttggact tatttggagt gttttgtatt atattatttt
    13681 tagatggttc attactcaat tcaacgttct aacgtcagga cgaggagaag aagtagattc
    13741 taaagaaatt tctgaatccg cagattcaac ttcaaatatt gcagattatt taaaacagga
    13801 tagcctacaa attatcagag ccttgggtgg atcaaataat atagaagatg tagatgcttg
    13861 tgtgacacgt ttacgtgtag ctgtaaaaga agttaatcaa gttgataaag cacttttaaa
    13921 acaaattggt gcagttgatg tcttagaagt gaagggtggc attcaagcaa tctatggagc
    13981 aaaagcaatc ttatataaaa atagtattaa tgaaatttta ggtgtagatg attaagtact
    14041 tactgactta ataaaaaaca gaggagagtg atggatgagt aggatgaaat gaaatcgcat
    14101 acaagaaata aagaactcat tatccaagtt ggatacgctt attacatagg agaatacaaa
    14161 tgaaatttag aaaattagct tgtacagtac ttgcgggtgc tgcggttctt ggtcttgctg
    14221 cttgtggcaa ttctggcgga agtaaagatg ctgccaaatc aggtggtgac ggtgccaaaa
    14281 cagaaatcac ttggtgggca ttcccagtat ttacccaaga aaaaactggt gacggtgttg
    14341 gaacttatga aaaatcaatc atcgaagcgt ttgaaaaagc aaacccagat ataaaagtga
    14401 aattggaaac catcgacttc aagtcaggtc ctgaaaaaat cacaacagcc atcgaagcag
    14461 gaacagctcc agacgtactc tttgatgcac caggacgtat catccaatac ggtaaaaacg
    14521 gtaaattggc tgagttgaac gacctcttca cagatgaatt tgttaaagat gtcaacaatg
    14581 aaaacatcgt acaagcaagt aaagctggag acaaggctta tatgtatccg attagttctg
    14641 ccccattcta catggcaatg aacaagaaaa tgttagaaga tgctggagta gcaaaccttg
    14701 taaaagaagg ttggacaact gatgattttg aaaaagtatt gaaagcactt aaagacaagg
    14761 gttacacacc aggttcattg ttcagttctg gtcaaggggg agaccaagga acacgtgcct
    14821 ttatctctaa cctttatagc ggttctgtaa cagatgaaaa agttagcaaa tatacaactg
    14881 atgatcctaa attcgtcaaa ggtcttgaaa aagcaactag ctggattaaa gacaatttga
    14941 tcaataatgg ttcacaattt gacggtgggg cagatatcca aaactttgcc aacggtcaaa
    15001 catcttacac aatcctttgg gcaccagctc aaaatggtat ccaagctaaa cttttagaag
    15061 caagtaaggt agaagtggta gaagtaccat tcccatcaga cgaaggtaag ccagctcttg
    15121 agtaccttgt aaacgggttt gcagtattca acaataaaga cgacaagaaa gtcgctgcat
    15181 ctaagaaatt catccagttt atcgcagatg acaaagagtg gggacctaaa gacgtagttc
    15241 gtacaggtgc tttcccagtc cgtacttcat ttggaaaact ttatgaagac aaacgcatgg
    15301 aaacaatcag cggctggact caatactact caccatacta caacactatt gatggatttg
    15361 ctgaaatgag aacactttgg ttcccaatgt tgcaatctgt atcaaatggt gacgaaaaac
    15421 cagcagatgc tttgaaagcc ttcactgaaa aagcgaacga aacaatcaaa aaagctatga
    15481 aacaatagtc cttagttatt ctataaaaag tagtttttta aagaacctaa gagtgtatac
    15541 ccccttttcc ctctacacag atagtgtaag aaaagggggc ttttgtttaa aatgtaagaa
    15601 actgtcacga aattaaaatg aagttcttac ataagcgaac cataaaaaat ttcattttga
    15661 ttttaaaaca gttcaagaaa gtcaaaaaat tattctattt gaaagagagg tgccgactgt
    15721 gaaagtcaat aaaatccgta tgcgggaaac agtgatttcc tacgctttcc tagcaccagt
    15781 attattcttc tttgtcatct ttgtgttggc tccgatggtg atgggcttca ttacaagttt
    15841 ctttaactac tcaatgacta aatttgagtt tgtgggctta gataactata tccgtatgtt
    15901 taaagatcct gtctttacaa aatctctgat taacacagtt attttggtta ttggatctgt
    15961 accagttgtt gttctattct cactctttgt agcatctcag acctatcatc aaaatgtcat
    16021 tgccagatcc ttctaccgtt tcgtcttctt ccttcctgtt gtaacgggta gtgttgccgt
    16081 gacagttgtt tggaaatgga tttatgaccc gctatcaggg attctaaact ttgtccttaa
    16141 gtcaagccac atcatcagcc aaaacatttc ttggttggga gataaaaact gggcattgat
    16201 ggcgattatg attattctct tgaccacttc agttggtcag cccatcatcc tttatatcgc
    16261 tgccatgggg aatattgaca attcactggt tgaagcggcg cgtgttgatg gcgcaactga
    16321 gtttcaagtt ttttggaaga ttaaatggcc aagccttctt ccaacaactc tttatattgc
    16381 aatcatcaca acaattaact catttcagtg tttcgccttg attcagcttt tgacatctgg
    16441 tggtccaaac tactcaacaa gtaccttgat gtactacctt tacgaaaaag ccttccaatt
    16501 gacagaatac ggctatgcca acacaattgg tgtcttcttg gcagtcatga ttgctatcgt
    16561 aagctttgtt caatttaaag tacttggaaa cgacgtagaa tactaaagaa aggagacagc
    16621 tatgcaatct acagaaaaaa aaccattaac agcctttact gttatttcaa caatcatttt
    16681 gctcttgttg actgtgctgt tcatctttcc attctactgg attttgacag gggcattcaa
    16741 atcacaacct gatacaattg ttattcctcc tcagtggttc cctaaaatgc caaccatgga
    16801 aaacttccaa caactcatgg tgcagaaccc tgccttgcaa tggatgtgga actcagtatt
    16861 tatctcattg gtaaccatgt tcttagtttg tgcaacctca tctctagcag gttatgtatt
    16921 ggctaaaaaa cgtttctatg gtcaacgcat tctatttgct atctttatcg ctgctatggc
    16981 gcttccaaaa caagttgtcc ttgtaccatt ggtacgtatc gtcaacttca tgggaatcca
    17041 cgatactctc tgggcagtta tcttgccttt gattggatgg ccattcggtg tcttcctcat
    17101 gaaacaattt agtgaaaata ttcctacaga gttgcttgaa tcagctaaaa tcgacggttg
    17161 tggtgagatt cgtaccttct ggagtgtagc cttcccgatt gtgaaaccag ggtttgcagc
    17221 ccttgcaatc tttaccttca tcaatacttg gaatgactac ttcatgcaat tggtaatgtt
    17281 gacttcacgt aacaatttga ccatctcact tggggttgcg accatgcagg ctgaaatggc
    17341 aaccaactat ggtttgatta tggcaggagc tgcccttgct gctgttccaa tcgtcacagt
    17401 cttccttgtc ttccaaaaat ccttcacaca gggtattact atgggagcgg tcaaaggata
    17461 atactctgcg aaaatcgaat gcaaactacg tcagcttcac cttgccatac ttaagtattg
    17521 cctgcggtta gcttcctagt ttgttcttca attttcattg agtataggaa aatcaatcta
    17581 tcaagataca gaagtatatt ttatagattt agagaatata gaggttataa gtgtctacaa
    17641 aatggagggt atgcagttac tttatgaagt tttgtcagac acttatcaac ttaagaatgg
    17701 ttttagttaa ctatcagaaa cgaaggaaag agtatgattt ttgacgattt gaaaaacatc
    17761 accttttaca aagggattca tcccaattta gacaaggcta tcgactacct ctaccaacat
    17821 cgtaaagatt cattcgaatt aggaaagtat gagattgatg gagataaagt ctttctagtt
    17881 gttcaggaaa atgtcctcaa tcaagttgag aataatcaat ttgaacacca taagaactat
    17941 gcagatttgc atttgctgat agaagggcat gaatattcga gctacggttc acgtatcaaa
    18001 gacgaggcag tagcattcga cgaagcgagt gacattggct ttgttcattg tcatgaacac
    18061 tacccgctct tgttgggtta tcacaatttt gcgattttct tcccaggtga gccacatcag
    18121 ccaaatggtt atgcaggcat ggaagaaaag gttcgaaaat atctctttaa aatcttgatt
    18181 gattaaaaat aggatgaatt gtttttttgt aaagctttga taatactcta ccatgaaatt
    18241 gatctttgtg aggtagagaa atgagaataa aatatttaaa aattggtatc ttctaagtat
    18301 gctgcaagag ctagtttctt agatggacag gggattacag ttgatgagat gtcctggata
    18361 attaggggca ttgtgaatgg attgattggt agatacataa aattaggtac ttatgcagct
    18421 aagtatggta ttagtatggc gcgctcgatc ttaagtaggg cagctgcaac tgcggcagca
    18481 agagtaagat tattgactaa gatttttgga tggattttac gaatagctgt gctcgcagct
    18541 gatgtatatg gtaattttgc caacaatatt gctgcagctt gggatgcaca tgataaaatc
    18601 cctaacaatg gtcgtataaa cttttaaaat gcgagaatga aagcactttg tattttttta
    18661 ttgtatatgt tagcttggac agtgcttgca atgataatcc gtggagggct agatggattt
    18721 gatgaacaca cttggcgtaa tattttagct agtgcgttgt cctcgctata catacattat
    18781 atatccatag atagaaaaag aaaaaagtcc aaaagaaaaa agaaaaaata gatttgttca
    18841 tggtagggac ttatgaaagc tttactaaca aaaaagaaaa cagtttacaa agaaaaatga
    18901 tggaggagca aacatggcac aaaaaggagt aagccttatc aaggcagcat ttgatacaga
    18961 taactttctc atgcgtttta gtgagaaagt cttggacatc gtgacagcca atcttctttt
    19021 tgtcgtctct tgtttgccca tcgtgacgat tggagtggct aaaatcagcc tctacgagac
    19081 catgttcgaa gttaagaaga gcagacgggt gcctgttttt aaaatctatc taagatcttt
    19141 caagcaaaat ctgaaactag gtcttcagct gggtttaatg gagttaggaa ttgtgtttct
    19201 taccctttca gatctctatc ttttctgggg tcaaacagct ctgcccttcc aattgctgaa
    19261 agccatttgt ctaggcattc tgattttcct tacgattgtg atgttggcta gctatccaat
    19321 cgcggcacgt tatgatttaa cttggaaaga agtgttacaa aaagggctta tcttggctag
    19381 ttttaacttt ccttggttct tcctcatgtt agccattctt gtcctcattg tgatggttct
    19441 ttatctgtcc gccttcagtc tactcttagg tggctcagtc ttcctacttt ttgggtttgg
    19501 actattggtc tttatccaga ctggattgat ggagaaaatt ttcgcaaaat accaatagga
    19561 gccttatttc tgaaactact ttcaaaggct ccaaacgcta ttctataagc gagaaactaa
    19621 aatctaagtg tctataagat attgaaagcc ttttcggtaa agtgtatact aaagaagtaa
    19681 agaaaaatct gctttagcag aaaataaaaa taataggaga aaatctatgt cagatttgaa
    19741 aaaatacgaa ggtgtcattc cagccttcta cgcatgttat gatgatcaag gagaagtaag
    19801 cccagaacgt acgcgtgcct tggttcaata cttcattgat aaaggtgttc aaggtcttta
    19861 tgtcaatggt tcttctggtg aatgtatcta ccaaagcgtt gaagatcgca agttgatttt
    19921 ggaagaagtc atggcggtag ccaaagataa attgaccatt attgcccatg ttgcttgcaa
    19981 taatactaaa gatagtatgg aacttgctcg ccatgctgaa agcttgggag tagatgctat
    20041 tgcaacgatt ccaccaattt atttccgctt gccagaatac tcagttgcca aatactggaa
    20101 cgatatcagt tctgcagctc caaacacaga ctacgtgatt tacaacattc ctcaattggc
    20161 aggggttgct ttgactccaa gcctttacac agaaatgttg aaaaatcctc gtgttatcgg
    20221 tgtgaagaac tcttctatgc cagttcaaga tatccaaacc tttgtcagcc ttggtggaga
    20281 agaccatatc gtctttaatg gtcctgatga gcagttccta ggaggacgcc tcatgggggc
    20341 tagggctggt atcggtggta cttatggtgc tatgccagaa ctcttcttga aactcaatca
    20401 gttgattgcg gataaggacc tagaaacagc gcgtgaattg cagtatgcta tcaacgcaat
    20461 cattggtaaa ctcacttctg ctcatggaaa tatgtacggt gtcatcaaag aagtcttgaa
    20521 aatcaatgaa ggcttgaata ttggatctgt tcgttcacca ttgacaccag tgactgaaga
    20581 agatcgtcca gttgtagaag cggctgctgc cttgattcgt gaaaccaagg agcgcttcct
    20641 ctaatctaaa aggaggtatt tatgacatat tacgttgcaa ttgatatcgg tggaaccaac
    20701 atcaagtatg gtttggttga tcaagagggg caacttcttg aatcgcatga aatgccaact
    20761 gaggcgcata agggtggacc tcatatctta caaaagacca aagatatcgt agctagttat
    20821 ttagaaaaag gcccagtagc aggtgttgcc atatcttctg ctgggatggt ggatccggat
    20881 aagggtgaga ttttctatgc tgggccgcaa atccctaact acgcaggcac ccagttcaaa
    20941 aaggaaatcg aagaaagctt tactattcct tgtgagattg aaaatgatgt caactgtgca
    21001 ggtcttgctg aggcagtatc tggttcaggc aagggagcaa gtgtgacact ttgcttgacc
    21061 attggaacag gtatcggtgg ttgcttgatt atggatagga aagtcttcca tggttttagc
    21121 aattcagcct gtgaagtcgg gtatatgcat atgcaggatg gagcttttca ggatctcgct
    21181 tctacaacag ctttagtgaa atatgtagct gaagcccatg gagaagatgt tgatcagtgg
    21241 aatggccgac gtatctttaa ggaagctact gaaggaaaca aaatctgcat ggaaggcatt
    21301 gaccgtatgg ttgactatct aggaaaaggt ctggcaaata tttgctacgt tgccaatcca
    21361 gaagtggtta ttcttggtgg tggtatcatg gggcaagagg ctatcctcaa acctaagatc
    21421 cgcacagcct tgaaagaggc tttggtacca agtttagcag aaaaaacacg attagaattt
    21481 gcccatcacc aaaatacagc agggatgttg ggtgcatatt atcattttaa gacaaaacaa
    21541 tcctagtttg gctcagccaa actaggattt tcttacacgt ttttgtctac gatagccgtt
    21601 gagtttttta ttttcccagt agctattaaa gattttttcc ttgctttcgc gattgatttc
    21661 caaaaagtag gcataaatca aatcgataaa gaagagcata ggaagttgag cggatattcg
    21721 ttggatatag gagggttggc tgtgggtggc tacaagaaca gtctctgtat aggtctggct
    21781 atctttattg ggaacacttg taaagagtac agtctttgcc cccatctcct tggcatctaa
    21841 tagactatct aaaatagaag gagttgagcc tgaaagtgag aagcccagta ctagacaatt
    21901 tccatccatg atgctggttg tccaggcaaa gccgtcttgg tctgtcaaag cttcgcagac
    21961 cacacctagt cgcataaaac gtaatttcat ttcacgggcg acgaggccag aactccctgt
    22021 tccaaagaag tagatacgct cagcatcttc gattagctgg gcaattcgct ctagttggat
    22081 ttcgtcaatc aagtcttgtg tttgttccct catattgcta taacttctga ggactcgttt
    22141 ggtcagtgga ctgtgcttgg agacttggtt ggcttgattt tctgcctgat gttggtattg
    22201 gaaaataaat tctcggtagc cagtaaagcc acacttttta gcaaagcggg tcaaagcagc
    22261 ttgagaaata tgtaattttt gggtgacttg ttgagaagat aaatcatctg taatcgtttc
    22321 agcttgcaaa aaatagcgag cgatttcttg ctctaggtct gtcatttctt caaaatgtga
    22381 atcaatgata gttgcgatat ctggtttgtc catagggaaa gctcctttac atgagtcata
    22441 ctggaagact agatcaggga atagtcacac ttcattataa cacataatat aaggatagat
    22501 aaataaaaac gcatttctgt tttaaaaacg aaaaaatcga aaaagcttct ttcttttcca
    22561 taattttcta ctcaaattgt ggtacaatta agagtaagat tttaagttag aaatgagact
    22621 gatttgtatg agaaaattta acagccattc gattccgatt cggcttaatt tattgttttc
    22681 aatcgtcatt ttactcttta tgaccattat tggtcgtttg ttgtatatgc aggttttgaa
    22741 caaggatttt tacgaaaaaa agctagcctc agctagtcag accaagatta caagcagttc
    22801 agcccgtggg gaaatttatg atgctagtgg aaaacctttg gtagaaaata cgttaaagca
    22861 ggttgtttcc tttacgcgta gcaataaaat gacggctaca gacttaaaag aaacagctaa
    22921 aaagttactg acttatgtga gcatcagttc tccaaatttg acagaacgcc agctggcgga
    22981 ttactatttg gctgatcctg aaatctataa aaaaacagtg gaagctctcc caagtgagaa
    23041 acgcttggat tcagatggca atcgtctatc cgaatcagaa ctgtataaca atgcggtcga
    23101 tagtgtccaa acaagtcaac taaactatac agaggatgaa aagaaagaaa tctatctttt
    23161 tagtcagtta aatgctgttg gaaactttgc gacaggaacc attgctacag atcctctaaa
    23221 tgattctcag gtggctgtta ttgcctctat ttcaaaggag atgcctggca ttagtatttc
    23281 tacttcttgg gatagaaagg ttttggaaac ttccctttct tctatagttg ggagtgtatc
    23341 cagtgaaaaa gctggtctcc cagcggaaga agcagaagcc tatcttaaaa aaggctattc
    23401 tctaaatgat cgtgtaggaa cctcctattt ggaaaagcaa tatgaagaga ccttacaagg
    23461 aaaacgctcg gtaaaagaaa tccatctgga taaatatggc aatatggaaa gcgtggatac
    23521 aattgaggaa ggtagtaagg gaaacaatat caaactgacc attgatttgg ctttccaaga
    23581 tagcgtggat gctttactga aaagttattt caattccgag ctagaaaatg gtggagccaa
    23641 gtattctgaa ggtgtctatg cagtcgccct taacccaaaa acaggtgcgg ttttgtctat
    23701 gtcagggatt aaacatgact tgaaaacggg agagttgacg cctgattcct tgggaacggt
    23761 aaccaatgtc tttgttccag gttcggttgt caaggcggcg accatcagct caggttggga
    23821 aaatggagtc ttgtcaggaa accagacctt gacagaccag tccattgtct tccaaggttc
    23881 agctcccatc aattcttggt atactcaggc ttacggttca ttccctatca cagcggtcca
    23941 agctctggag tattcatcaa atacctatat ggtccaaaca gccttaggtc ttatggggca
    24001 aacctatcaa cccaatatgt ttgtcggcac cagcaatcta gagtctgcta tggagaaact
    24061 gcgttcaacc tttggcgaat atggcttggg tactgcgaca ggaattgacc taccagatga
    24121 atctactgga tttgttccca aagagtatag ctttgctaat tacattacta atgcctttgg
    24181 gcagtttgat aactatacgc cgatgcagtt ggctcagtat gtagcaacta ttgcaaataa
    24241 tggtgttcgt gtggctcctc gtattgttga aggcatttat ggtaataatg ataagggagg
    24301 actgggtgac ttgattcagc aactgcaacc gacagagata aataaggtca atatatccga
    24361 ctccgatatg agcatcttgc accaaggttt ttatcaggtt gcccatggta ctagtggatt
    24421 gacaactgga cgtgcctttt caaatggcgc cttggtatcc attagcggaa aaacaggtac
    24481 agccgaaagc tatgtggcag atggtcagca agcaaccaat accaatgcgg tggcctatgc
    24541 cccatctgat aatccccaaa tcgctgttgc agtggtcttt cctcataata ccaatctaac
    24601 aaatggtgta ggaccttcca ttgcgcgtga cattatcaat ctgtatcaaa aataccatcc
    24661 aatgaactag aaaggaaatt atgctttatc caacacctat tgccaagttg attgacagtt
    24721 attctaagtt accaggtatc gggattaaga cggctacgcg tctggccttt tatacgattg
    24781 ggatgtctgc tgatgatgtc aatgaatttg caaaaaatct cctttctgct aagagagaat
    24841 tgacatattg ttctatttgt ggacgtttga cagacgacga tccttgttct atctgtactg
    24901 atccgactcg tgaccagaca acaattttag ttcttgagga tagtagagat gtggcagcca
    24961 tggaaaatat ccaagaatac catggactct atcatgtcct tcatggcctc atttctccta
    25021 tgaatggtat cagtccggac gatatcaatc tcaagagcct tatgactcgt cttatggata
    25081 gtgaagtttc agaagtgatt gtggcgacta atgctacagc ggatggtgaa gcgacttcca
    25141 tgtatctttc acgtttgctc aagccggctg gtatcaaggt tacgcgtcta gcacgaggtc
    25201 tcgctgtggg agcggacatt gagtatgcgg acgaagtgac actcttacga gcgattgaaa
    25261 atcggacaga gttgtaagtg taggcaaatt tacgaactcc attcatttat aaaaaatcaa
    25321 agaggctgaa aatcgttcct atcggcctct ttttgtatag tgtgatgagt aggatcaggt
    25381 tcaagtttta aaaaaccaag caaatatgat atactaaaga gcgagtattc tagtagaatt
    25441 aggacaaata atatgaaaca aacgattatt cttttatatg gtggacggag tgcggaacgc
    25501 gaagtctctg tcctttcagc tgagagtgtc atgcgtgcgg tcaattacga ccgtttcaca
    25561 gtcaagactt tctttatcag tcagtcaggt gactttatca aaacacagga atttagtcat
    25621 gctccggggc aagaagaccg tctcatgacc aatgaaacca ttgattggga taagaaagtt
    25681 gcaccaagtg ctatctacga agaaggtgca gtggtctttc cagtccttca cgggccaatg
    25741 ggagaagatg gctctgttca aggattcttg gaagttttga aaatgcctta cgttggttgc
    25801 aacattttgt catcaagtct tgccatggat aaaatcacga ctaagcgtgt tctggaatct
    25861 gctggtattg cccaagttcc ttatgtggct atcgttgaag gcgatgatgt gactgctaaa
    25921 atcgctgaag tggaagaaaa attggcttat ccagtcttca ctaagccgtc aaacatgggg
    25981 tctagtgtcg gtatttctaa gtctgaaaac caagaagaac tccgtcaagc cttaaaactt
    26041 gccttccgat atgacagccg tgtcttggtt gagcaaggag tgaatgcccg tgaaattgag
    26101 gttggcctct tgggtaacta cgatgtcaag agcacgctac ctggagaagt tgtcaaggac
    26161 gttgcctttt atgactacga tgccaagtat attgataaca agattactat ggatattcct
    26221 gccaaaatca gtgatgatgt ggtggctgtc atgcgtcaaa atgcagaaac agccttccgt
    26281 gccattggtg gccttggtct atctcgttgc gatttcttct atacagataa gggagagatt
    26341 tttctcaacg agctcaatac catgccaggt tttacccagt ggtctatgta cccactactt
    26401 tgggacaata tggggatcag ctacccagaa ctaatcgagc gtttggttga ccttgccaag
    26461 gaaagttttg acaagcgcga agcgcatttg atataaaatg aaagagaggg tagaagccag
    26521 aaccatcact gcacggtgac tagagttctc ggacttcagc cctttttaaa ggagtagaaa
    26581 tgaaattaac aatccatgaa attgcccaag ttgttggagc caaaaatgat atcagtatct
    26641 ttgaggacac ccagttagaa aaagctgagt ttgatagtcg tttgattgga actggagatt
    26701 tatttgtgcc acttaaaggt gcgcgtgatg gccatgactt tattgaaaca gcctttgaaa
    26761 atggtgcagc agtaaccttg tctgagaaag aggtctcaaa tcatccttac attctagtag
    26821 atgatgtttt gacagccttt caatccctag catcctacta tcttgaaaaa acgactgttg
    26881 atgtctttgc tgttacaggt tcaaatggca agacaacgac taaggatatg ttggcgtatt
    26941 tactgtcaac aagatacaag acctacaaaa cacaaggcaa ttacaataat gagattggcc
    27001 ttccttacac agttctccac atgcctgaag gaacagaaaa gttggtcttg gagatggggc
    27061 aggaccactt gggagatatt catctcttgt ctgaattggc tcgtccaaaa acagccatcg
    27121 tgaccttggt tggagaagct catttggcct ttttcaaaga tcgttctgag attgctaaag
    27181 gaaaaatgca aattgcagac ggaatggctt caggttcctt gcttttagcg ccggctgacc
    27241 ctatcgtaga ggactatttg ccaactgata aaaaggtggt tcgttttggt caaggagcag
    27301 agctggaaat tactgacttg gttgagcgca aagatagtct gaccttcaag gccaatttct
    27361 tagagcaagt ccttgatttg ccagtaactg gcaagtataa tgcgacaaat gctatgattg
    27421 catcctatgt tgccttgcaa gaaggagttt cagaggagca aattcatcag gccttccaag
    27481 atcttgaatt gacgcgtaac cgtaccgaat ggaagaaagc agccaatgga gcagatatcc
    27541 tgtctgatgt atacaatgcc aatccaactg ctatgaagtt gattttagag actttctctg
    27601 ccattccagc caatgaaggt ggcaagaaaa ttgcggtttt agcggacatg aaggaactgg
    27661 gtaaccagtc agttcaactt cataatcaga tgattttgag cctttctcca gatgtgcttg
    27721 ataccgtgat tttctatgga gaagacattg ctgaattagc ccaattggcc agtcaaatgt
    27781 tcccaattgg ccacgtttac tacttcaaga aaacagaaga ccaagaccaa tttgaagacc
    27841 tagtcaagca ggtcaaggaa agcctcagtg ccaatgatca aatcttgctc aagggctcta
    27901 actctatgaa cctagctatg ttggtagaaa gtttagaaaa tgaaaccaag tgattttgtt
    27961 aagtatctgc aaagaatgat tgcccttaca gatactggct taacctttac aaaagatcct
    28021 tttgaccgtg agcgctacga ggacttgcga agtctgttat ctgaaatgtt gaatcaggga
    28081 tcagacctgg atgcagaaga agtagcagaa gtcttgaaac caacttcagc ttatgcgact
    28141 cccttaatgg acgtccgtgc ttggattgtt gaggatgaga agatttgtct ggttagggga
    28201 caaggagagg gtagttgggc tttgccaggt ggctttggtg aagtcggcta ttctccaact
    28261 gaaaatattc tcaaggaaat tgaagaagaa accggtttta aagccaaagt tgaaagactg
    28321 ctagctgttt ttgatatcaa tcgtttccaa ctacagagca aacaatatgc aaagtttgtt
    28381 tttgaatgta agcttctcga tggacaattc caagaaaatc aagaaattgc agaccttcaa
    28441 ttttttgcca ttgatcaact gccagtctta tctgaaaaac gcattaccaa ggagcaaata
    28501 gagattcttt ggcaggttta tcaaggtcag agggagcaat atcttgacta agaagatgat
    28561 tatcgtattt ttaaatccat ttttaacaac tagcatggta taataatatg caggaaaatt
    28621 ttgaattatg aggaagacta gatgaattta tgggatattt tctttacgac tcaggcaacc
    28681 aagccgccca aatttgacct tttttggtat gttagcctat ttacgctctt agccttaacc
    28741 ttttatacag cccatcgcta tcgtgaaaag aaggtttacc aacgattttt ccaaatcttg
    28801 cagactgttc agttaatcct tctttatggt tggtactggg tcaatcatat gccactgtca
    28861 gaaagcctac ccttttacca ttgccgtatg gctatgtttg tggtactctt gcttcctggt
    28921 caatccaaat ataaacaata ctttgcatta ttgggaacat ttgggacatt agcagccttt
    28981 gtttatccag tgccagatgc ttaccctttt ccacatatca ccattctatc ctttatcttt
    29041 ggtcatttag cactcttggg gaactctcta gtttatctat tgagacagta taatgcgcga
    29101 ttgctggatg tgaagggaat ttttctcatg acctttgccc taaatgcctt gatttttgtg
    29161 gtcaatttgg tgacaggtgg cgattacgga tttttgacaa aaccgccatt ggttggggat
    29221 cacggtctag tagctaatta tttacttgtt tcaattgtgc tggtagctac tatcagtttg
    29281 actaagaaaa tcttagaatt ctttttagct caagaagcag aaaaaatgat tgtaaaggaa
    29341 gcttaacaca gagctttctt ttttgctctt agagagtttt tacaatcagc ttataaaata
    29401 agaatttctg aatagacaaa ctcaaaaaat ggctgggaaa tttaggaaaa aagcaagcac
    29461 gattaaattt tttgtgttat aatattttgt gaatagctat gcctatgttt agctatggaa
    29521 taatacgaag tgcgaaactt ggaagataga gaggaagcga tgtaatggct agagaaggct
    29581 tttttacagg tctagatatt ggaacaagct ctgtcaaggt gcttgtggcc gagcagagaa
    29641 atggtgaatt aaatgtaatt ggcgtgagta atgccaaaag taaaggtgta aaggatggaa
    29701 ttattgttga tattgatgca gcagcaactg ctatcaagtc agccatttcc caagcggaag
    29761 aaaaggcagg catttcgatt aaatcagtaa atgtcggctt gcctggtaat cttttgcagg
    29821 tagaaccaac tcaggggatg attccagtaa catctgatac taaggaaatt acggatcaag
    29881 atgttgaaaa tgttgtcaaa tcagctttga caaagagtat gacacctgac cgtgaagtca
    29941 ttacctttat tcctgaagaa tttattgtgg atggtttcca agggattcgt gacccacgtg
    30001 gcatgatggg ggttcgcctt gaaatgcgtg gtttgcttta tacaggacct cgtactatct
    30061 tgcacaattt gcgtaagacg gttgagcgtg caggtgttca ggttgaaaat gttatcattt
    30121 caccactagc aatggttcag tctgttttga acgaagggga acgtgaattt ggtgctacag
    30181 tgattgatat gggggcaggt caaacgactg tcgctacaat ccgtaatcaa gaactccagt
    30241 tcacacatat tctccaagaa ggtggagatt atgtaactaa agatatctcc aaggttttga
    30301 aaacctctcg caaattagcg gaaggcttga aactgaatta cggggaagcc tatccgcctc
    30361 ttgcaagcaa agaaaccttc caagtagagg ttattggaga agtagaagca gtcgaagtga
    30421 cggaagccta cttgtcagaa attatttctg cacgaatcaa gcacatcctt gaacaaatca
    30481 agcaagaatt agatagaagg cgtctattgg acctccctgg tggtattgtc ttaatcggtg
    30541 ggaatgccat tttaccaggt atggttgagc ttgctcagga agtctttggc gtccgtgtca
    30601 agctttatgt tccaaatcaa gttggtatcc gtaatccagc ctttgcgcat gtgattagtt
    30661 tatcagaatt tgcgggtcaa ttaacagaag ttaatctttt ggctcaggga gcgataaaag
    30721 gtgagaatga cttaagtcat cagccaatta gttttggtgg gatgctgcaa aaaacagctc
    30781 agtttgtaca atcaacgcct gttcaaccag ctcctgctcc agaagtagag ccggtggcgc
    30841 ctacagaacc aatggcggat ttccaacaag cttcacaaaa taaaccgaaa ttagcagatc
    30901 gtttccgtgg cttgatcgga agcatgtttg acgaataaag aggaaaaata aattatgaca
    30961 ttttcatttg atacagctgc tgctcaaggg gcagtgatta aagtaattgg tgtcggtgga
    31021 ggtggtggca atgccatcaa ccgtatggtc gacgaaggtg ttacaggcgt agaatttatc
    31081 gcagcaaaca cagatgtaca agcattgagt agtacaaaag ctgagactgt tattcagttg
    31141 ggacctaaat tgactcgtgg tttgggtgca ggaggtcaac ctgaggttgg tcgtaaagcc
    31201 gctgaagaaa gcgaagaaac actgacggaa gctattagtg gtgccgatat ggtcttcatc
    31261 actgctggta tgggaggagg ctctggaact ggagctgctc ctgttattgc tcgtattgcc
    31321 aaagatttag gtgcgcttac agttggtgtt gtaacacgtc cctttggttt tgaaggaagt
    31381 aagcgtggac aatttgctgt agaaggaatc aatcaacttc gtgagcatgt agacactcta
    31441 ttgattatct caaacaacaa tttgcttgaa attgttgata agaaaacacc gcttttggag
    31501 gctcttagcg aagcggataa cgttcttcgt caaggtgttc aagggattac cgatttgatt
    31561 accaatccag gattgattaa ccttgacttt gccgatgtga aaacggtaat ggcaaacaaa
    31621 gggaatgctc ttatgggtat tggtatcggt agtggagaag aacgtgtggt agaagcggca
    31681 cgtaaggcaa tctattcacc acttcttgaa acaactattg acggtgctga ggatgttatc
    31741 gtcaacgtta ctggtggtct tgacttaacc ttgattgagg cagaagaggc ttcacaaatt
    31801 gtgaaccagg cagcaggtca aggagtgaac atctggctcg gtacttcaat tgatgaaagt
    31861 atgcgtgatg aaattcgtgt aacagttgtt gcaacgggtg ttcgtcaaga ccgcgtagaa
    31921 aaggttgtgg ctccacaagc tagatctgct actaactacc gtgagacagt gaaaccagct
    31981 cattcacatg gctttgatcg tcattttgat atggcagaaa cagctgaatt gccaaaacaa
    32041 aatccacgtc gtttggaacc aactcaggca tctgcttttg gtgattggga tcttcgccgt
    32101 gaatcgattg ttcgtacaac agattcagtc gtttctccag tcgagcgctt tgaagcccca
    32161 atttcacaag atgaagatga attggataca cctccatttt tcaaaaatcg ttaagtaaat
    32221 gaatgtaaaa gaaaatacag aacttgtttt tcgagaagtt gcagaggcta gtctgagtgc
    32281 tcatcgagag agtggttcgg tctctgtcat tgcagttacc aagtatgtag atgtaccgac
    32341 agcggaagcc ttgcttccgc taggtgttca tcatatcggt gaaaatcgtg tagataagtt
    32401 tctggaaaaa tatgaagctt taaaagatcg agatgtgact tggcatttga ttggtacctt
    32461 gcaaagacgt aaggtgaaag atgtcattca atacgttgat tatttccatg cattggactc
    32521 agtaaagcta gcaggggaaa ttcaaaaaag aagtgaccga gtcatcaagt gtttccttca
    32581 agtaaatatt tctaaagaag aaagcaaaca cggtttttcg agagaggaac tgctggaaat
    32641 cttgccagag ttagccagac tagataagat tgaatatatt ggtttaatga cgatggcacc
    32701 ttttgaggct agcagtgagc agttgaaaga gattttcaag gcggcccaag atttacaaag
    32761 agaaattcaa gagaaacaaa ttccaaatat gcctatgacc gagttaagta tgggaatgag
    32821 tcgtgattat aaagaagcga ttcaattcgg ttccactttt gttcgtatag gtacatcatt
    32881 ttttaagtag gagagaacca tgtctttaaa agatagattc gatagattta tagattattt
    32941 tacggaggat gaggattcaa gtctccctta tgaaaaaaga gatgagcctg tgtttacttc
    33001 agtaaattct tcacaggaac cggctctccc aatgaatcaa ccttcacagt cggctggtac
    33061 aaaagagaac aatatcacca gacttcatgc aagacaacag gaattggcaa atcagagtca
    33121 gcgtgcaacg gataaggtca ttatagatgt tcgttatcct agaaaatatg aggatgcaac
    33181 agaaattgtt gatttattgg caggaaacga aagtatcttg attgactttc agtatatgac
    33241 agaggtgcag gctcgtcgtt gtttggacta tttggatgga gcttgtcatg ttttagctgg
    33301 aaatttgaaa aaggtagctt ctaccatgta tttgttgaca ccagtgaacg ttattgtaaa
    33361 tgttgaagat atccgtttac cagatgaaga tcaacagggt gagttcggtt ttgatatgaa
    33421 gcgaaataga gtacgataat gattttttta attcgtatga tttataatgc agtggatatt
    33481 tactccctga ttttggtagc cttcgctgtc atgtcttggt ttccaggtgc ctacgaatcc
    33541 agtttaggtc gttggattgt agcgttggtg aaaccagtgc ttgctccctt gcaacgcctg
    33601 cctttacaga tagcgggtct tgatttatct gtttgggttg cgattgtttt ggttcgattt
    33661 ttaggagaaa acctagtgcg ttttctggcg atgataggat gaataaaggg atttatcagc
    33721 atttctccat agaagatcgt ccatttcttg acaagggaat ggaatggata aagaaggtag
    33781 aagatagcta tgctcctttt ttaactcctt ttatcaatcc tcatcaggag aagctattaa
    33841 agattttggc caaaacctat ggtcttgctt gtagcagtag tggggaattc gtctcgagtg
    33901 agtatgttcg agttttatta tacccagatt atttccaacc agagttttca gattttgaaa
    33961 tatctctcca ggaaattgtg tattccaata aatttgaaca tttaacgcat gctaagattt
    34021 tagggacagt catcaatcaa ttagggattg aacggaaact ttttggagat atcctagtag
    34081 atgaagaacg ggcgcagatt atgattaatc agcagtttct tcttctcttt caagatggac
    34141 taaagaaaat tggtcgtata cctgtttcgc tggaggaacg tcctttcacc gagaaaatag
    34201 ataagctaga acagtatcga gaactggatt tatctgtgtc tagttttcga ttagatgttc
    34261 ttttatcaaa tgttttgaaa ctatctagga atcaagcaaa ccagttgatt gaaaagaaac
    34321 ttgtccaagt aaattatcat gtggtagaca aatcagatta cactgttcaa gttggagact
    34381 tgattagtgt gagaaaattt ggtcgcttga gattacttca agataaggga caaacgaaaa
    34441 aagagaagaa aaaaataacc gtccagttat tattaagtaa gtgaggaata gaatgccaat
    34501 tacatcatta gaaataaagg acaagacttt tggaactcga ttcagaggtt ttgatccaga
    34561 agaagtcgat gaatttttag atattgtggt tcgtgattac gaagatcttg tgcgtgcgaa
    34621 tcatgataaa aatttgcgta ttaagagttt agaagagcgt ttgtcttact ttgatgaaat
    34681 aaaagattca ttgagccagt ctgtattgat tgctcaggat acagctgaga gagtgaaaca
    34741 ggcggcgcat gaacgttcaa acaatatcat tcatcaagca gagcaagatg cgcaacgctt
    34801 gttggaagaa gctaaatata aggcaaacga gattcttcgt caagcaactg ataatgctaa
    34861 gaaagtcgct gttgaaacag aagaattgaa gaacaagagc cgtgtcttcc accaacgtct
    34921 caaatctaca attgagagtc agttggctat tgttgaatct tcagattggg aagatattct
    34981 ccgtccaaca gctacttatc ttcaaaccag tgatgaagcc tttaaagaag tggttagcga
    35041 agtacttgga gaaccgattc cagctccaat tgaagaagaa ccaattgata tgacacgtca
    35101 gttctctcaa gcagaaatgg cagaattaca agctcgtatt gaggtagccg ataaagaatt
    35161 gtctgaattt gaagctcaga ttaaacagga agtggaagct ccaactcctg tagtgagtcc
    35221 tcaagttgaa gaagagcctc tgctcatcca gttggcccaa tgtatgaaga accagaagta
    35281 gctccaatgc atccgatagg tccaacacca gctacagaaa ctgttgattc aataccggga
    35341 tttgaagcac cgcaagaatc tgttacaatt ttataagaaa tattctgaga acaatatctt
    35401 atccttatat ttccagcgag caggagatgg tgtgagtcct gtaatcccta ttgataagat
    35461 tatcctctca aaaactcaag tctgaagcta gtaagatttg acgtttccca cgttacggga
    35521 taagagggag aaagactaaa tctttttccg aataaaggtg gtaccacgat tttcgtcctt
    35581 tttggaagtc gtggttttta atttgttatt atttataaag gagataccat gaaactcaaa
    35641 gacaccctta atcttgggaa aactgaattc ccaatgcgtg caggccttcc taccaaagag
    35701 ccagtttggc aaaaggaatg ggaagatgca aaactttatc aacgtcgtca agaattgaac
    35761 caaggaaaac ctcatttcac cttgcatgat ggccctccat acgctaacgg aaatatccac
    35821 gttggacatg ctatgaacaa gatttcaaaa gatatcattg ttcgttctaa gtctatgtca
    35881 ggattttacg caccatttat tcctggttgg gatactcatg gtctgccaat cgagcaagtc
    35941 ttgtcaaaac aaggtgtcaa acgtaaagaa atggacttgg ttgagtactt gaaactttgc
    36001 cgtgagtacg ctctttctca agtagataaa caacgtgaag attttaaacg tttgggtgtt
    36061 tctggtgact gggaaaatcc atatgtgacc ttgactcctg actatgaagc agctcaaatt
    36121 cgtgtatttg gtgagatggc taataagggt tatatctacc gtggtgctaa gccagtttac
    36181 tggtcatggt catctgagtc agcacttgct gaagcagaga ttgaatacca tgacttggtt
    36241 tcaacttccc tttactatgc caacaaggta aaagatggca aaggagttct agatacagat
    36301 acttatatcg ttgtctggac aacgactcca tttaccatca cagcttctcg tggtttgacg
    36361 gttggtgcag atattgatta cgttttggtt caacctgctg gtgaagctcg taagtttgtc
    36421 gttgctgctg aattattgac tagcttgtct gagaaatttg gctgggctga tgttcaagtt
    36481 ttggaaactt accgtggcca agaactcaac cacatcgtaa cagaacaccc atgggataca
    36541 gctgtagaag agttggtaat tcttggtgac cacgttacga ctgactctgg tacaggtatt
    36601 gtccatacag cccctggttt tggtgaggac gattacaatg ttggtattgc taataatctt
    36661 gaagtcgcag tgactgttga tgaacgtggt atcatgatga agaatgctgg tcctgaattt
    36721 gaaggtcaat tctatgaaaa ggtagttcca actgttattg aaaaacttgg taacctcctt
    36781 cttgcccaag aagaaatctc tcactcatat ccatttgact ggcgtactaa gaaaccaatc
    36841 atctggcgtg cagttccaca atggtttgcc tcagtttcta aattccgtca agaaatcttg
    36901 gacgaaattg aaaaagtgaa attccactca gaatggggta aagtccgtct ttacaatatg
    36961 atccgtgacc gtggtgactg ggttatctct cgtcaacgtg cttggggtgt tccacttcct
    37021 atcttctacg ctgaagatgg tacagctatc atggtagctg aaactattga acacgtagct
    37081 caactttttg aagaatatgg ttcaagcatt tggtgggaac gtgatgccaa agacctcttg
    37141 ccagaaggat ttactcatcc aggttcacca aacggcgagt tcaaaaaaga aactgatatc
    37201 atggacgttt ggtttgactc aggttcatca tggaatggag tggtggtaaa ccgtcctgaa
    37261 ttgacttacc cagccgacct ttacctagaa ggttctgacc aataccgtgg ttggtttaac
    37321 tcatcactta tcacatctgt tgccaaccat ggcgtagcac cttacaaaca aatcttgtca
    37381 caaggttttg cccttgatgg taaaggtgag aagatgtcta aatctcttgg aaatactatt
    37441 gctccaagcg atgttgaaaa acaattcggt gctgaaatct tgcgtctctg ggtaacaagt
    37501 gttgactcaa gcaatgacgt gcgtatctct atggatatct tgagccaagt ttctgaaact
    37561 taccgtaaga ttcgtaacac tcttcgtttc ttgattgcca atacatctga ctttaaccca
    37621 gctcaagata cagtcgctta cgatgagctt cgttcagttg ataagtacat gacgattcgc
    37681 tttaaccagc ttgtcaagac cattcgtgat gcctatgcag actttgaatt cttgacgatc
    37741 tacaaggcct tggtgaactt tatcaacgtt gacttgtcag ccttctacct tgattttgcc
    37801 aaagatgttg tttacattga aggtgccaaa tcactggaac gccgtcaaat gcagactgtc
    37861 ttctatgaca ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc tcacactgcg
    37921 gaagaaatct ggtcatatct tgagtttgaa acagaagact tcgtccaatt gtcagaatta
    37981 ccagaagttc aaacttttgc taaccaagaa gaaatcttgg atacatgggc agccttcatg
    38041 gactttcgtg gacaagcaca aaaagccttg gaagaagctc gtaatgcaaa agttatcggt
    38101 aaatcacttg aagcacactt gacagtttat ccaaatgaag ttgtgaaaac tctactcgaa
    38161 gcagtaaaca gcaatgtagc acaacttttg atcgtgtctg agttgaccat cgcagaagga
    38221 ccagctccgg aagctgccct tagcttcgaa gatgtagcct tcacagttga acgtgctact
    38281 ggtgaagtat gtgaccgttg ccgtcgtatc gacccaacaa cagcagaacg cagctaccag
    38341 gcagttatct gtgaccactg tgcaagcatc gtagaagaaa actttgcgga agcagtcgca
    38401 gaaggatttg aagagaaata agattgaaaa gtctaggcaa aattcaattt gagaagaaaa
    38461 gacaactaat tttatagtct attaaacgca ttgtatcacg tttttgaata cctgatatga
    38521 tgcgtttttt atttatttta aaaatttgcg aggtatgact ttttatactc aacaagaatc
    38581 aaagagaaac ttagcaagct aacagtagta agataaaata ggaatttgat attagggata
    38641 agattggtaa atagtgtaat atttttacaa caataaattt atatagttat ttctggtttc
    38701 tgaaaagtat tatattttat ttcatattat acaaattttt attttataat atcagaacat
    38761 acttttttta aaagcaaata tgatacaatt ttatttgaaa aaaataaaaa aggagatttt
    38821 attataaaat taaaaagact tgctttaatt agtggtatcg tcggtcttgt gggaggaatt
    38881 ttacttctta ttggtccttt tgtcttgttg ggaatagcgg taaacacagc tgctacaact
    38941 cttaatggag gagctactgc aggggctttt tcaggtgtag ccttactctt gaatgccttg
    39001 aagattgcaa atcttgttct tggtatcatt gctattgttt actataaagg agataagcgt
    39061 gtaggtgcag ctccgtctgt actaatgatt gtttctggtg gagttagtct cattctattc
    39121 cgttcttagg atgggttggg gggatttttg ctattatcgg aggatctcta ttcctttcaa
    39181 cattgaagaa attcaaatca gaagaataaa aggtatttta gcatgaaaag aacaaaaaag
    39241 tttatcggta taggagtagc tctattatct ctttctcttc tagttgcatg tggaacataa
    39301 agttcaaaga atacttcaac aagtaatgat gagaagacag tagcaacatc caatagttca
    39361 aaagaaacaa tcactttcga tacaccggtt gtaacagacg atgcgattga atcaatacgc
    39421 acttatgcag attatataga tctttataaa aatatttttg atgattattt tactaaagct
    39481 gaggaaggtt tcaaaggcat agctatggaa aataatgact cgtttactaa actaaaagag
    39541 tcaactcaaa aattattcga tgcgcagaaa aaaaggttaa ataatgaaga tagaatagaa
    39601 acaaccaaaa acaatgtgat tgccaaacat tgtcaaacag tcctttcctt tttggttttg
    39661 actagctttt ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg aaacctcgga
    39721 aaatttaaag gagaatccat ctaatggtaa aattggtttt tgctcgccac ggtgagtctg
    39781 aatggaacaa agctaacctt ttcactggtt gggctgatgt tgatttgtct gaaaaaggta
    39841 cacaacaagc gattgacgct ggtaaattga tcaaagaagc tggtatcgaa tttgaccaag
    39901 cttacacttc agtattgaaa cgtgctatca aaacaactaa cttggctctt gaagcttctg
    39961 accaattatg ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac tacggtggtt
    40021 tgactggtaa aaacaaagct gaagctgctg aacaatttgg tgatgagcaa gttcacatct
    40081 ggcgtcgttc atacgatgta ttgcctccaa atatggaccg tgatgatgag cactcagctc
    40141 acacagaccg tcgttatgct tcacttgacg actcagtaat cccagatgct gaaaacttga
    40201 aagtgacttt ggaacgtgct cttccattct gggaagataa aatcgctcca gctcttaaag
    40261 atggtaaaaa cgtattcgta ggagctcacg gtaactcaat ccgtgccctt gtaaaacaca
    40321 tcaaaggttt gtcagatgat gagatcatgg acgtggaaat ccctaacttc ccaccattgg
    40381 tattcgaatt cgacgaaaaa ttgaacgttg tttctgaata ctaccttgga aaataaaaaa
    40441 ttgtaagcct aggattgatt tctaggcttt ttatgttagt atggaagtat gataaggaat
    40501 aaaaaacaag attatgtact ggcctacaaa caaccagctt caaccactta catgggttgg
    40561 gaagaagaag ctttaccgat aggtaatggt tctttaggag caaaagtatt tggccgtata
    40621 ggggctgaac ggattcaatt taatgaaaaa agtctctggt ctggaggtcc acttcctgat
    40681 agttcagatt atcagggtgg aaatcttcag gatcagtatg tttttttagc tgagattcgg
    40741 caggctttgg agaagagaga ttacaatctg gctaaggaac tggctgagca gcacctaatt
    40801 gggccaaaaa cgagtcaata tgggacctat ctgtcttttg gggatattca cattgagttc
    40861 agccagcaag gtacgacttt gtctcaggtg acggactatc agagacagct gaatattagt
    40921 aaggcacttg tgacgacttc ttatgtctat aagggaacgc gatttgaacg tgaagctttt
    40981 gcgagttttc cagatgatct cttggttcag cgttttacta aggaaggggc ggaaactcta
    41041 gattttacta tagaactatc cttgacctgt gatttggctt ctgatgaaaa gtatgagcag
    41101 gaaaaatctg attacaagga gtgtaagttg gatattactg attctcatat cttgatgaag
    41161 ggaagagtta aggataatga tctgcggttt gctagttatc tagcttggga aacggatgga
    41221 gatattagag tttggtcaga tagggttcag atatcaggag ccagttatgc caatctcttc
    41281 ttggccgcta agacggattt tgcccaaaat cctgctagca attatcgcaa gaaactagat
    41341 ttagagcaac aggtgataga cttggtggac acagctaaag aaaagggcta tacccaattg
    41401 aaatcaaggc atatcgagga ctaccaagcc ttattccagc gtgttcaatt ggatttggaa
    41461 gctgatgttg acgcatccac tacagatgat ttgttaaaaa attataagcc acaagaaggg
    41521 caggctttgg aggagctgtt cttccagtat ggacggtatt tattgattag ttcgtccaga
    41581 gactgcccag atgctctacc agctaaccta cagggagtct ggaatgcggt cgacaatcct
    41641 ccttggaatt cggactatca cttaaatgtc aatctgcaga tgaattattg gccagcctat
    41701 gttaccaatc tcctagaggc ggtctttccg gtcatcaact atgtagatga tttgcgtgtc
    41761 tatggtcgtc tagcggctgt aaagtatgca ggaatcgtct ctcagaaagg tgaggaaaat
    41821 ggttggttgg ttcatactca agcgactccc tttggttgga cggcacctgg ttgggattac
    41881 tattggggtt ggtcaccagc tgccaatgcg tggatgatgc aaaccgttta tgaagcctat
    41941 tcattttata gggaccaaga ctatctcagg gagaaaattt atcccatgtt gagggaaacg
    42001 gttcgttttt ggaatgcctt tttacataag gatcagcagg cgcagcgttg ggtgtcttct
    42061 ccgtcttatt ctccagaaca tgggccgatt tcgattggca atacctatga ccaatctctg
    42121 atttggcagt tatttcatga ttttattcag gctgctcagg aattgggact ggatgaggac
    42181 ttgttgactg aggttaagga gaagtctgat ttactaaatc ctttgcaaat cactcaatct
    42241 ggtcgaatca gggagtggta tgaggaggaa gagcagtatt ttcaaaatga gaaagtggag
    42301 gcccagcacc ggcacgcttc ccatctagtg ggactctatc ctggcaatct ctttagctac
    42361 aagggacaag agtatattga agcggcgcgt gctagcctca atgatcgtgg agatggcggc
    42421 acaggctggt ccaaggctaa taagatcaat ctctgggcgc gtttgggaga tggcaatcgc
    42481 gcccataaat tattggcaga gcagttaaag acatccacct tgccaaatct ttggtgtagc
    42541 catcctcctt ttcagataga tggtaatttt ggtgctacta gtggcatggc agaaatgtta
    42601 ctccagtctc atgcagctta tctggtacct ctagctgccc tacctgatgc ttggtcaaca
    42661 ggttctgttt caggcttaat ggcacgtgga cattttgaag tgagcatgag ctgggaagat
    42721 aaaaaactct tacagttgac cattttatca aggagcggag gagatttgcg agtttcttat
    42781 ccagatattg agaagagtgt gattaaaatg aatcaagaaa aaataaaagc gaaatgcatg
    42841 gggaaagatt gtatttcggt ggcaacagca gaaggtgatc ttgttcaatt ttatttttaa
    42901 gaagatgtta taaggcagta atttgaaact gccttttaat aaggatttaa gaatataagc
    42961 agttttcaac tagttgaaaa agcgttataa tgataatagg aagtaatact caatgaaaat
    43021 caaagagcac aaacaaggaa gctagccgca ggttgctcaa aacagtgttt tgaggttgca
    43081 gatggaagct gacgtggttt gaagagagat tttcgaggag tataatttgt ttgatagagg
    43141 gtgggtctga tggcttatat tgagatgaaa cactgttaca agcgttatca ggttggggac
    43201 acggagattg tggctaatcg tgatgtgaat tttgagattg aaaaggggga gctggttatt
    43261 atccttggtg cttcaggtgc aggcaagtca acagttctta accttcttgg gggaatggat
    43321 accaatgatg aaggggaaat ctggattgat ggtgttaata ttgcggatta tagttcccac
    43381 cagcgcacca attaccgtag aaatgatgtg gggtttgttt ttcagtttta taatctagtt
    43441 tctaatctga cagctaagga aaatgtggaa ctggcttctg aaattgtgac agatgccttg
    43501 aatcctgatc aggtcttgac agatgtaggt ctggctcatc gtctaaataa ctttccagcc
    43561 cagctttctg gaggggagca acagcgagtc tccattgcac gcgcggtagc caaaaatcct
    43621 aaaattctcc tttgtgatga accgactgga gccttggatt atcagacggg caagcaggtt
    43681 ttgaaaattc tccaagacat gtctcgtcaa aagggagcga cggtgatcat tgtgactcat
    43741 aatggagctt tggcgcccat tgctgatcgc gtgattcata tgcacgatgc cagtgtcaag
    43801 gatgtggtgc tcaaccagca tcctcaggat attgacagtt tggagtacta gcatgatcaa
    43861 gcgaaaaact tattggaagg acttaattca gtccttcaca ggctccaagg ggcgtttttt
    43921 atccatcttg atcctgatga tgttgggatc tctagcctta gtaggcctca aagtaaccag
    43981 tcccaacatg gaggcgacag ctaatgctta tttaacaact gctcaaacct tagatttggc
    44041 agtcatgtct aactatggct tggatcaagc agaccaagaa gaactaaaac agacggaggg
    44101 cgcagaggtc gagtttggct atttgacaga tgtgactatg gataatgggc aggatgccat
    44161 tcggctgtac tccaaaccag agcgaatttc aacctttcag ctaagaaagg gacgacttcc
    44221 tcagtcagac aaggaaatcg ctttgaccac tcatttgcaa ggccaataca gcgtgggaca
    44281 ggagattagt tttaaagaaa aagaagaggg tcattcctct ttaaaagacc atacttatac
    44341 cattactggt tttgtggatt cggctgaaat cctctcccag cgagatatgg gctacgcagg
    44401 aagtggaagt gggactctga cagcctatgg ggtgatttta cctagtcaat ttgatcagaa
    44461 agtctacaat atagctcgtt tgaaatatca agatttagca ggtttaaatg ccttttcatc
    44521 agcttatgaa gaaaaatcca agcaacatca ggaagagctt gaacaaattt tatcagataa
    44581 tggcaaggta cgtctgcgac ttttgaaaaa agaaggacaa gagtctctag acaaggggca
    44641 agagaccctt gacaaggctc agactaattt gcaggaaggc aagcgtcgtt tagcagctgc
    44701 tcaagctcgt atacaggctc aagaaagtca actagccttg tttcctcaag ctcagagaga
    44761 gcaggctagt gctcaactta cccaagccaa gcaggaattg ggcaaggaag aggacaaact
    44821 aaagcaagct gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac atcagcaagt
    44881 cttggatgat ttggcggagc caaggtatca ggtttataat cgtcagacca tgccaggtgg
    44941 tcagggctat cttatgtata gcaatgcttc atccagtatt cgagcagtgg gcaatatctt
    45001 tcctgtggta ctttatgccg tagcagccat ggtgaccttt acgaccatga ctcgctttgt
    45061 agacgaagag cgaactcatg cagggatttt taaggccttg ggttatcgta gtaaggatat
    45121 tatcgccaag tttctccttt atggactagt agctgggact gtcggaacgg ctctaggtag
    45181 tatacttggt cattatttgc tagccagtgt aatttcaagt gtcattacaa aaggcatggt
    45241 ggtgggagaa actcagattc agttctattg gacctatagc ttactagctt ttgtcttgag
    45301 cttgttggcg agtgtgttac cagcctatct ggtggcttgg agggaacttc atgacgaagc
    45361 agcccagctt ctacttccta aacctcctgt caaaggagct aaaatcttat tggagcgtat
    45421 cggttttatc tggcgtcgtc tcagttttac tcataaggta acagcccgca acatctttcg
    45481 ttataagcag agaatgttga tgacaatctt tggtgtggca ggttctgtag ctctgctctt
    45541 tgcaggtttg ggaatccaat cttctgtagc aggagttccg tctaaacagt ttcaacaaat
    45601 ccaacagtat cagatgcttg tctctgaaaa tcctagtgcg accaatcagg acaaggtaga
    45661 gctagcagaa gtgttgaaag ggcaggagat actagcctac cagaaaatct attctaaagc
    45721 gctatacaag gatttcaaag gcaaagctgg tcttcaaaac attactctta tgatgataga
    45781 gaaggaagat ttgactccct ttatccatct tcaacatcat cagcaggagc tgacattaaa
    45841 agatggcatc gttattacag ctaaactcgc ccagctggca ggtgtcaagg ttgggcagac
    45901 tttagaaatt gaaggtaagg aactaaaggt cgttgctatt actgagaact acgttggtca
    45961 ctttatttat atgagtcagg ctagctatga gcaactttac ggacagctac cccaagccaa
    46021 cacttatctg gtctcattaa gggataccag tgcaactagt atcgaaagtc aggcgggctt
    46081 gcttatgaat caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca ttcgactctt
    46141 cgactctatc gctagctcac tcaatcagac catgaccatc ttggtcatcg tatcggttct
    46201 attagctatt gtcatccttt acaatctgac caatatcaac gtagctgaga gaatccgtga
    46261 actctccact atcaaggttc ttggttttca taataatgaa gtcaccctct acatttaccg
    46321 tgagacgatt gtgctgtccc ttgtgggaat cgtacttggt ctgatagctg gtttctattt
    46381 acaccaattt ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc cgcaggtagg
    46441 ctgggaagtc tatgtaatcc cagtggcagc agtaagcatc attttgacct tgcttggttt
    46501 cttcgtcaat tattatctga gaaaggttga tatgttagaa gccctgaaat ctgtagagta
    46561 aggtagttat ttttagctga ttgaacttct atttactaat attcaaaaat cctccgtttc
    46621 aaagagcagg gaactctttg tgacagagga ttttttctat agggctttag cagctgcaat
    46681 tgcggcttcg aagtttggct cagaattgat attatccacg tattcaacgt agcgaatcgt
    46741 attgtcagta tcgaggacaa agactgcgcg tgctaatagg tgccattcgt tgatcaagag
    46801 ggcataatcg cgcccgaaag aatggtcaaa gtagtctgaa agcataatgg cattgtcaag
    46861 gccttcagca ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa cagtcaatac
    46921 gaccgtgttg tccagtccag ccaattcttc attaaaacga cgtgtttgag ttgagcagat
    46981 gcctgtatcg atagaaggaa cgacactcaa gacttttttc ttgccatcaa aatcagccag
    47041 agatttttta gaaagatctg ttgtagtaag agaaaaatca agcgccttgt cgccgacttg
    47101 tagttgttta cctgtaaagc tcacaggatt tccgagaaaa gttaccatag gatactccaa
    47161 tcttttttct tccattttag ctgaaacagt cggaattttc caatgatttg accggaaata
    47221 tgggcataga aaaaacgcca gctcatgtga gaatgacgtt tttcataggt ttattttgcc
    47281 aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct gtcgccttct
    47341 ttaccttgtt ctgcgataga gtcagtaaag atttgagcgt agattgggat gtttgtgtct
    47401 tgagaaacag ttttcattgg acggtcatcc acacttgatt ctacaaagag tgatggaact
    47461 tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc ttcttcttca
    47521 gtattgattt cccagatgta agcacttggg acaccatagg ctttagagaa gtatttgaat
    47581 gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa tttatcctta
    47641 ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt ttcatagaat
    47701 tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc aaaaataata
    47761 ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt ttgaccttca
    47821 aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc agttttcttg
    47881 gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt gataccgtta
    47941 tagaaaatca aattagcctc agaagttttc ttaacgtctt caggaagtgg ttcgtattcg
    48001 tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc agcaatattt
    48061 ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg accagaagtt
    48121 gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa gagaacgagt
    48181 aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc cttattttaa
    48241 caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga agctaatgag
    48301 aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa aactatagcc
    48361 aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga aaatcatact
    48421 tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca tggctacaat
    48481 caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga gtaccatgag
    48541 aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt catcaaagga
    48601 agttatcaag agttgcttga agaaaatcca gattaacaag aggatagctg cccccacacc
    48661 catagtaata aacatatccg tatcttggac ggccaggata ttaccaaaaa ggatatggaa
    48721 aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta agaaagaaga
    48781 aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga tgtaggtaat
    48841 gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa ggcccaagat
    48901 gaaggatagg gctacacctg gtaagacagc atgtgaaatg gcatctccca tgagtgacat
    48961 cccgcgtaga ataatgaaac atcccacagc tccagctaca atcccgacga caatagctgt
    49021 tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt ctgcaatcat
    49081 aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt ggtttcggta
    49141 aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa gacttgatcg
    49201 aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt
    49261 ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagagtcaat cccagcaaag
    49321 ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat caagacccgc
    49381 tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc taggccgacg
    49441 atttcaaggg cctcttgcac tttcttccaa tgtttagcct ttaaacttcg aaagagagga
    49501 atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa gttgtagtcg
    49561 atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac ttccttgtca
    49621 tcgagaaatg cctgaccttg atgtgggata attcccaaca taccttttaa tagtgttgat
    49681 ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag cactagtgaa
    49741 atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttctat acgtatcata
    49801 aacttatatt cctcctgtct cttaatatac attaaaaaaa aaattaagtc aagttaattt
    49861 ttgaaaaaat taaaataata actgaaaaat agattctaaa gataactttc aggataaatt
    49921 tctaaattat aaaacgcata gtatcaagtg taaaaaactt ggaattatgc gttttatcat
    49981 ggaaagattt tttataatag ctaaaaaata atagttaaat ggttattaat tgcattccct
    50041 agtgattttt gttaagataa atgcaaatac aaatgaaagc gagaacaaga tgacacgtta
    50101 tcaagatgat ttttatgatg ctatcaatgg agaatggcaa cagacagctg aaatcccagc
    50161 agataagtct caaactggag gttttgttga tttagaccag gaaattgaag acctgatgct
    50221 ggcgacaaca gacaagtggt tagcaggtga agaggtgcct gaggatgcta tcttggaaaa
    50281 ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag agagaagctg acggtatcac
    50341 acctgtctta ccactcctta aagaattcca agaattggaa acttttgcgg attttacagc
    50401 taaactagca gagtttgagc ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc
    50461 agactttatg gatgctagaa tcaatgttct atgggctagc gctccaagca caatcttgcc
    50521 agatacgacc tactatgcag aagaacatcc tcagcgcgaa gaactcttga ctctttggaa
    50581 agaaagcagc gcaaatctcc tcaaggctta tgatttctct gatgaagaaa ttgaagactt
    50641 gctagaaaaa agacttgaat tggaccgccg agttgcggca gtggtgctct ctaatgaaga
    50701 aagttcagaa tatgctaaac tctatcatcc atattcttac gaagatttca agaaattcgc
    50761 gcctgcccta cctttggatg acttcttcaa agcagttatt gggcaattac cagacaaggt
    50821 tattgtagac gaggaacgtt tctggcaagc agcagagcaa ttctacagtg aggaagcctg
    50881 gtctctcctt aaagcaacct tgattttgag tgttgtcaat ctttcaacca gctatttaac
    50941 agaggatatc cgtgttttgt ctggtgccta cagccgtgcc ctttctggag ttccagaggc
    51001 aaaagataag gtcaaagcag cttatcatct agcacaagaa cctttcaagc aagccctggg
    51061 tctttggtac gcccgtgaga agttctctcc agaagccaag gcggatgtgg agaaaaaagt
    51121 ggcaaccatg attgatgttt ataaggagcg tctgcttaag aatgactggc tcactccaga
    51181 aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa ccttatattg gctatccaga
    51241 agaattgcct gcacgttaca aggataaggt agtgaatgaa actgccagtc tttttgagaa
    51301 tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga accagcctgt
    51361 agattataag gaatggggca tgcctgctca tatggtcaat gcctactaca atcctcagaa
    51421 gaacctgatt gtctttccag cggccatttt acaggcgcct ttctatgact tgcatcagtc
    51481 atcttctgct aactacggtg gtattggggc agtgattgcc catgaaattt cccacgcctt
    51541 tgatactaac ggggcttcct ttgacgaaaa tggtagcctc aaggattggt ggacagagag
    51601 cgactatgct gccttcaagg agaaaacaca aaaagtcatt gaccaatttg atggacagga
    51661 ttcttatgga gcaaccatta acggtaaatt gactgtatca gaaaacgtgg ctgacttggg
    51721 aggaatcgca gcagcgcttg aagcagctaa gagagaagca gacttctcag cagaagagtt
    51781 cttctacaac ttcggtcgca tctggcgcat gaaaggtcga ccagaattta tgaaactttt
    51841 ggctagcgtc gatgtgcacg caccagccaa actccgtgtc aatgtgcaag taccaaactt
    51901 cgacgatttc tttacaacct atgatgtcaa agaaggagac ggaatgtggc gttcaccaga
    51961 ggagcgcgtg attatttggt aatacaaaaa atctagtcat cagaaaaagg catccaatca
    52021 cgtgtgaaaa ccttgatagg atgccttttg taatagaaag atttgctgga tagtttactt
    52081 aaatttcgat tgtcatcatc ttgctaaaaa aagggattga aggccttttc gtgagcgata
    52141 gtagtagctg gaccatgtcc tggatagaca tcgtagtttg gtagggtgaa gagttgggtc
    52201 tggatactat gaaggagttg ctccatgcta ccagtcggaa ggtcggtccg tccgatagtt
    52261 tcgcggaata gagcatctcc cgtcaagact aggtgagcat caggaaagac tagggaaaca
    52321 ccaccgatag agtgccctgg ggtcggtaga accttaaaac gaaattcctc tagttggtat
    52381 tcttcgtgaa agacaaaggt gtgttctgca ggttttgtga ccacatctgc catatcatcg
    52441 tggcgaggga gaccggagag attatcgaca ggagtgtaga gccagctggc ttcgctctct
    52501 gcgatataga caggaggatt gccaaacgtc tcgcgaacca agtccagact catgatatgg
    52561 tcataatggg cgtgggtcaa gagaatagca cagatcggtt tgttgatctt ctcgattgtc
    52621 tgacgaatgg cttcccaatg actaccagga tcgacgacga tgaggtgctt ttcgccttct
    52681 agataatagg tattttcata ggcaacagga ttcacggttt tatagatttt catactagct
    52741 ccaatctcaa agaatatact aatactcttc gaaaatctct tcaaaccgcg tcaactttat
    52801 ctgcaacctc aaagcagtgc tttgaacagc ctgcggctag ctttctagtt tgctctttga
    52861 ttttcattga gtataaatta agtatagcac agttagggag aataggtaag gatttaaaat
    52921 gaacttaaaa accagcatga ctagatgaag acaggctggt tatcaattta tcaatattgg
    52981 aaaggtgtca attgcccttc ataggttgca taaactccgt cattagcttg tttgatagac
    53041 gtgatgttta gagtgctacc gtagttggct tctcatttgt cgctatattc actataagtt
    53101 atcctactgg gcaggttctg gtcgttagca tagtattgaa cgagtttttt atagctttgc
    53161 tggctgaata ggaacaggca gcaaactcct aacattagga gagcaaagat agaaatagca
    53221 gtttttttca taggtattct ccttataaac taaaggatag aagaaagtat cttgaggatt
    53281 tttatactct tcaaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atatatgtga
    53341 ctgactttgt cagtcttatc tacaacctca aagcagtgct ttgagcaacc tgcggctagt
    53401 ttcctagttt gctctttgat tttcattgag tattaattcc aaaatccagt caaggtacca
    53461 gtgtatgtga tacgagttcc accgtttatc tttcgtatct tcaatggaat tggggaaatc
    53521 agaaagtctt tgggttacaa tatggtttcc gttcttctat ctctccttct atcacctaag
    53581 tttaaaatct aacttcgtag tatattatgg gccaataatt cagaattatc aagcaatttt
    53641 gaattatttt tttcttattc tgttccaatc tagttttcat attcttaaaa aagtgataaa
    53701 atggtaggaa gaattggaga gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag
    53761 ttgtcgcttt aaccaaagaa tatttaacgg aagaggatgt tcattttgtc cataaggcct
    53821 tggtctatgc tgttgaatgc cacagtggtc aatatcgcaa atcaggcgag ccttatatca
    53881 ttcaccctat ccaagtggca ggtattttag ctaagctaaa gctggatgct gtaacagtag
    53941 cttgtggatt cttgcatgat gtggtggaag atacagatgc gaccttggac gatttggaaa
    54001 gagagtttgg tcctgatgtg cgggtgattg ttgacggagt taccaagctt ggcaaggtcg
    54061 agtacaaatc gatcgaggag caattagcgg aaaatcatcg caagatgctc atggccatgt
    54121 ctgaggacat ccgcgttatt ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc
    54181 tgaaacatct tcgaaaagac aagcaggagc gtatttccaa agaaaccatg gaaatctatg
    54241 ccccacttgc ccatcgtttg gggatttcca gtgtcaaatg ggaattagaa gacttgtctt
    54301 tccgttatct caatccaacg gagttttaca agattaccca tatgatgaag gaaaagcgca
    54361 gggagcgtga ggccttggtg gatgaggtag tcacaaaatt agaggagtat acgacagaac
    54421 gtcacttgaa agggaagatt tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa
    54481 tgcaggacaa gagaaaacgg tttgaggaaa tctatgatct gattgctatt cgttgtattt
    54541 tagataccca aagtgatgtt tatgccatgc ttggttacgt gcatgaattt tggaaaccga
    54601 tgccaggtcg cttcaaagac tatattgcca accgcaaggc caatggttat cagtctatcc
    54661 atacgactgt ttatggacca aaagggccga ttgaattcca gattcgaacc aaggaaatgc
    54721 acgaggtggc tgagtacggg gttgcggctc actgggctta taagaaaggt ataaaggggc
    54781 aagttaacag caaggaatca gctattggaa tgaactggat caaggagatg atggagctcc
    54841 aagaccaggc tgatgatgct aaggaatttg tggactctgt taaggaaaac tatttggctg
    54901 aggagattta cgtttttacc ccagatggag ctgtccgttc ccttcccaaa gattcaggac
    54961 cgattgattt tgcctacgaa atccatacca aggtcggtga aaaagcaact ggtgccaagg
    55021 tcaatggccg catggttcca ctgacaacca agttaaagac aggggatcag gttgaaatta
    55081 tcgccaaccc gaactccttt ggacctagcc gtgactggct caatatggtc aagactagca
    55141 aggcgcgcaa taagattcgc cagttcttta aaaaccaaga taaggaattg tctgtcaaca
    55201 agggtcgtga gatgctgatg gctcagttcc aagaaaatgg ctatgtggca aataaattta
    55261 tggacaagcg ccacatggat caagttctgc aaaagaccag ttacaagaca gaagactccc
    55321 tctttgcggc cattggtttt ggggaaatcg gtgcgattac cgtctttaat cgtctgactg
    55381 aaaaggaacg ccgtgaggaa gagcgtgcca aggccaaggc tgaggcagag gagcttgtca
    55441 aaggtggcga ggtcaaggtt gaaaataaag aaactctcaa ggtcaagcat gaggggggag
    55501 tggttattga aggtgcttct ggtctcctag tgcggattgc taagtgttgt aaccccgtgc
    55561 ctggtgacga tattgttggc tacattacca agggtcgtgg tgtggctatt caccgtgtgg
    55621 actgtatgaa cctgcgtgcc caagaaaact acgagcaacg tttccttgat gtggaatggg
    55681 aagaccagta ctctagctca aataaggagt atatggccca tatcgatatc tacggtctca
    55741 accgtacagg actgttgaac gatgtactgc aagttctttc aaatacaacc aagaatattt
    55801 caacggtcaa tgcccaacca accaaggata tgaagtttgc taatatccat gtgtccttcg
    55861 gtattgccaa cctctctaca ctgaccacgg ttgtcgataa aattaagagt gtgccagaag
    55921 tttactctgt caaacggacc aacggctagt tgtcctagct cttactagaa aggctattat
    55981 gaaaatcatt atccaacggg ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg
    56041 aaaaatcaat cagggacttt tattgctggt tggtgttgga ccagaggacc aagaggaaga
    56101 tttggactat gctgtgagaa aactggtcaa tatgcggatt ttttcagacg cagaaggcaa
    56161 gatgaacctg tctgtcaaag atattgaagg agaaatcctc tctatttctc agtttaccct
    56221 ctttgcggat actaagaaag gcaatcgtcc agcctttaca ggggcagcta aacctgatat
    56281 ggcatcagac ttctatgatg ctttcaatca aaaattagcg caagaagtgc ccgttcagac
    56341 aggtatcttt ggagcagata tgcaggttga gctggttaat aacggacctg ttaccattat
    56401 cctagatact aaaaagagat aagaaagacc aagcccagtc ggcttggtct ttctcatcta
    56461 tcataaaata ctccaaaaag aaatcggttc ttgatatgct tgggggaagt ctcttttcag
    56521 gctttggcag atgcgatagg aagggatgag atgtcctagg atgaggagag ttccctgaag
    56581 gaaaagtgga atatcactta aagacaccaa ggagagaatc atcaggctat cccataggag
    56641 aatttgtaaa gcaaaacgcc agaatctcgg tctaatctgg gaatagagtt aactaaagtg
    56701 gtcacaaagt tggtttgaaa gataggtcaa tagcacagga tgaaagaaaa tgagccaacc
    56761 gctataaatc aaaatccagt cccaagtaag ccccctttta aatgtcaaaa atgccagcat
    56821 gattccatca atgacaagga gttgaatggt tttgatgaag atgatttttt tcatgctaaa
    56881 acctcctttt ccttagagac actcccataa agagatgtgt ttgtcgtaaa agtctggata
    56941 gttttctctt aggtagtcag ctgtcatata ataaaaagta gaatggcaag cagtgataat
    57001 tgacataaga gatgaaaaac gctgagaact aatgaaggct aagagaacaa aaaatagaaa
    57061 atcaatggtg agaaccccta aatagtagaa gcgaatcttt ttattgattt gaggataaat
    57121 ctcagcgaat tgatgtttga gtcggacgat caagagaaat agcaggagtc cttgagcaag
    57181 gaagaaaatt aaaccagaga gcaagagcca ctcaaaagat gtctcgagtc taatgataaa
    57241 aaatgcaaat agtagcaaat caataactgc aattgctata aaatggattc tatagagttt
    57301 tttcatgaca agacctccct cttttatcta acttcattct actccaaaag aatgggagtt
    57361 acaactaaaa tgataaaaat agcagaaggg agattctctt aagttggcta gtattcttta
    57421 tttgagtttc cttctattat ctaacttctt catcattcca gacaaataaa gctccgattg
    57481 cattgaggat ataaaagatg tatttaccga tattggcgaa gtttccttga ataccagctt
    57541 ttgtcagctg aacgaaattg taaatcaacc aaaagcccca ctgagttgtt agttttaatg
    57601 cattcaaagc attggcaatg agggatagtg caaaggcaat agttgttacg taggcaagga
    57661 gattcatctt gccctcatat ccgatatagt tggtcacaaa ggcaaagagg aaggcgatga
    57721 tggaaatgat gatgaccgcc aattttacct gtttttggct tatttggttg ggtctgcctt
    57781 cttgcgaagc tttccatttc tttatagcaa aggtataaat gaggaaggtg acgggatagg
    57841 taatgatggc cgccttattt ccaaggatat aatcaatagc accggacaaa atggtattaa
    57901 caataccaaa gtaatttccc catttgctta atttccccgt gaaacgagtg gacaacatgg
    57961 aaatcccaac gttggttacg gaaatcaatc caaagggtac aagagctgtc catagtcccc
    58021 agtctacaaa tttatcgagg cgtgagttga gataaccaga tgcaatcgca atcccaacga
    58081 ccaaagcaac cccgaagagg tcaaaccatt tagatgtagc aaaaattttt agtgattttt
    58141 tcataggtta aactaccttt cttttttttt caaatattct accaccaaat gaaagtaaaa
    58201 taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg ggacttgaga
    58261 aattagttga ttttctcgac atagagttgt tttgcaatga ccatattcac ttgtaaatcc
    58321 tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt gacttggagc
    58381 tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa actatcgtgc
    58441 acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag gttattgatt
    58501 tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt tttagggaaa
    58561 cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc caagacctca
    58621 gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa aacttcaatc
    58681 aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt cagtagatag
    58741 ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat catttcagtt
    58801 acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat cttatgcagg
    58861 tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt cattcgtttc
    58921 ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct agctgtgact
    58981 ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg aaaatagctc
    59041 ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca gatgctcggc
    59101 agctaggagt ggatgaatac tggcttttgg gagatattct catgccaggg acaggacgta
    59161 gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg ggaaactggg
    59221 aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc agtcaacgct
    59281 atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa attgaagtgc
    59341 tccacaatca acctcttcaa cttcatcgtc agtttgggga tttgacggtg ggaattagcc
    59401 atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa caagaggagt
    59461 ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat attcaccagc
    59521 agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg attggccaac
    59581 ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg attttggagt
    59641 ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat gtggcagctg
    59701 aattgcagct ggctaaagac ctgagacttc cctattttga ggtttattat gaaagtctgg
    59761 tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct cagaaagagg
    59821 gctgcgatcg ggagttagac gactggttga aaagtggtaa cgattgacat tacaactaaa
    59881 aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa aaggagaaga
    59941 ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc attgccctcg
    60001 aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg gtcaatcctg
    60061 tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca gtagcgcgtg
    60121 gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta gatgtttatc
    60181 aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac aatccgaatc
    60241 ccaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg gagagaattc
    60301 agttgactat ggaggcagaa cttggtcaga ccagtctaga aaaagtcgtg gccgatgcag
    60361 agagtcagat gaaggattaa gagggataaa tgccctcttt ttttctttgg ataattatga
    60421 taaaatgtag ctattaaagg agtaagaaat gtatcttgtt ataggaattg tattagcctt
    60481 tatagtgtca ttttggaagg ataatagaag tttgtggaat ccagtattat ttttattatc
    60541 cttcatttca agttattttt atctatccta ccttttttat aaaaatggat acgagaatgt
    60601 tcagttagct ttttatgtat ttgcctttgt cttacttcct tttttgcttt ttctaagtgg
    60661 catcttttta atctataatg gggtcatttt gttgaaacga gagggacgtt ccaagcccca
    60721 ttatctctca atgctctttg atttttattg actattagat tctatttaaa aagacttaga
    60781 atgcacatga aagtatgtat tctaggtctt ttgttttgta tacatttaat tttcaagagt
    60841 attatctatt tttccatgca tggtaacgag tatcaatcaa taactgggta aggcgaccca
    60901 aggtttctct ttcttttgga gtgagggatt gagcttggac aaagagatga tgaatgtatt
    60961 caagcgcctt taaggaagcc aagtcattga tagagctaat accagcatca agaatagtgc
    61021 caaagaagag gtcgaagtag agctgaagtt cttcgtcagg gactgtggcc acccattctt
    61081 taaaggttgt gtctacttgc cggctatcac tgttggtctt atccagttga acgaagtgct
    61141 tgtcctcaat ctgccaacta aaggtatcgt gctgggcgat gccacccagg gcagtactct
    61201 gaacgatgat ttggtgagca ggaatttcca gcatcatacc gataatggaa ccttgtggaa
    61261 tgaatatctt gcttctatcc attatccttt gataacccgc agtctgtgtc aattcttgat
    61321 ggagaccagg tgcatcaaat gtataaactg ctgtgatctg attttgcaaa ctttgctcaa
    61381 tttggctagc agcatagata gcgagatttc ctcccttgga atgcccagcc agaataacct
    61441 tttgcttagg atgatgggca aaaaagttct ttaaatagcg aagggcgtgc ttttgagaag
    61501 gaatttcctt catataggtc aggtggaaat cttccttcca gccaatgata ctgtcatctg
    61561 tcccacgaaa gacaatcaga taggtatcga ggctgacacg ataagtcata gccgcaaatt
    61621 gcttttgcag ttcagggtcg atgtcgttga taaaatggga gagtttgcaa tttttgaagc
    61681 gcttgtgttg agccaattca tctaataatt gaaggcgatt tttgctagta agcatggtgg
    61741 gctctcttgg aacctgaggt gctagatcta aaagacgttg aggaagtgtg gagaccagat
    61801 tatcaaagga gaggtaggtg atttctatta aggttagaat gtctaactca ttcaagggaa
    61861 ggtcgtaata agaatcatat gcgacatctt tcagatagtc aaaaatattg gccataagag
    61921 ctcctttctt tttatttatc ttagcaaatt tccctcaaat tagctagtag catagcctgt
    61981 ttgtgctggc taaaaacagg ctatttcaaa ttcagtttca gaccatctag catggaaaaa
    62041 tctgttataa taatggaaaa ggagaagcgc atgcacaaga ttttattaat agaagatgat
    62101 caggtcattc gtcaacagat tgggaaaatg ctctctgaat ggggatttga agtggtcctg
    62161 gtagaagact ttatggaagt tttgagtcta tttgttcagt cggaacctca tctggtcctc
    62221 atggatattg gtttgccctt gtttaatggt tatcactggt gtcaggaaat ccgcaagatt
    62281 tccaaggtac ctatcatgtt tctttcttcg agagaccagg ctatggatat tgtcatggca
    62341 atcaatatgg gggcggatga ctttgtgacc aagccttttg accagcaggt tcttttagct
    62401 aaggttcagg gcttgttgcg tcgttcctat gagtttgggc gtgatgagag tttgctggaa
    62461 tatgctggtg ttatcctcaa taccaaatcc atggatttac attatcaagg gcaagtcttg
    62521 aatttgacca agaatgaatt ccagatttta cgcgtgttat ttgagcatgc aggcaacatc
    62581 gtagcacgtg acgacctgat gcgggaactt tggaacagtg actttttcat tgatgataat
    62641 accctctctg tcaatgtggc tcgtttgcgt aaaaagttgg aggagcaggg attggtagga
    62701 tttatcgaga ccaagaaagg aatagggtat ggattgaagc atgcttgatt ggaaacaatt
    62761 ttttctagcc tatctgcgct cccgtagtcg tctttttatc tatctgcttt ctttggcatt
    62821 tcttgtctta ctctttcagt ttttatttgc cagtctagga atttacttcc tctacttttt
    62881 cttcttgtgt tgctttgtaa ccatattatt tttcacttgg gacatattgg tggaaacgca
    62941 ggtctatcgc caggaacttc tctatggaga gagggaagcc aagtctcctt tggaaatagc
    63001 tttagcagaa aaattagaag cgcgtgagat ggaactctat cagcagaggt caaaagcaga
    63061 aagaaaactg acggatttgc tggattacta taccttgtgg gtccatcaga taaagacccc
    63121 cattgcagcc agtcaactct tagttgcaga agtggtcgac cgccaactga agcagcagct
    63181 agaacaggaa attttcaaaa tcgactccta taccaaccta gttttacagt acctgcgttt
    63241 agaaagtttc catgatgatt tggtcttaaa gcaggttcaa attgaggact tggtcaagga
    63301 aataattcgt aaatatgctc ttttctttat tcaaaaaggc ttaaatgtca atctacatga
    63361 ccttgataaa gaaatcgtga cggataaaaa gtggctgcta gtggttattg agcaaatcat
    63421 ctcaaacagt ctcaagtaca ccaaggaagg tggtctggag atttatatgg atgaccaaga
    63481 gctttgtatc aaagatacgg gaatcgggat aaaaaacagt gatgtcctcc gagtatttga
    63541 acgtggcttt tcaggataca atggccgttt gacccagcag tcctctggac ttggccttta
    63601 tctatctaag aaaatttctg aagaactggg gcaccagatt cgtatcgagt ctgaggtcgg
    63661 aaaaggaacg acagtgcgga ttcagtttgc tcaagtgaac ttagtccttg agtaaaaata
    63721 gatgagaaaa agcctccaga ttggaggctt ttatgctaga ctcttatttc tcaacgcgtg
    63781 atttgttggc gatatcagct aggatagctt gaacaaaatt atcaactgag acagtttgtg
    63841 tttctttttg gccgtagcga cgaacgttga ctgtttcgtc ttccatttct ttgtctccaa
    63901 caattaattg gtaaggaatc ttgctagttt gtgaagcacg gatcttgaac tgcatttttt
    63961 cattgcgctc atctacgtct gcacggacac cgcggtcacg gagtttcttg gctacttccc
    64021 aagcgtagtc cacgtgtttt tcgttagata ctgggataag ggttacttgg tgtggtgcca
    64081 gccatgttgg gaaggcaccc ttgtagttct caatcaagat agctgtgaag cgttccatag
    64141 ttgagataac cccacggtgg atcatgactg gacggtgatc ttcgccatca gctccgatgt
    64201 atttgaggtc gaagcgttct ggcaacaaga aatcaagttg gatagtagaa agggtttctt
    64261 cttttccaag ggcagtttta atctggatat ccaattttgg tccgtagaag gctgcttcac
    64321 cttcggcttc aaagtagtcc acgcccattt catcaagggc tgcacgaagc atggtttggg
    64381 cattttccca catctcatcg ttatcaaagt acttatgagt atcttgaggg tcacgaagag
    64441 agaggcggaa gcggtagtca gtcaagttga agtcttcata aacatcgata atcaactgaa
    64501 gggcacgttg gaattcttct tggatttgtt ctggagtaac gaataggtga ccgtcgttga
    64561 gtgacatttc acgtacacgt tgaaggccag tgagggcacc agatttttcg taacggtgca
    64621 tcataccgat ttcagcgata cggattggca attcacggta agagtgaaca tggtgtttga
    64681 aaacttggat gtggtgcgga cagttcattg gacgaaggac aaattcttcc ccgtcaccca
    64741 tgtccatggt tgggaacatg tcttcttggt aatgatccca gtggccagaa gtcttgtaaa
    64801 gctcaacaga agcaagtggt ggagtgtaga cgtgttggta gccagaagcc aactctttgt
    64861 ttacgatgta gcgttccaat tcacgacgga tagtcgcacc atttggcaac cagaatggca
    64921 aaccttgtcc cacttcttgt gaaatcataa agaggtcaag ctctttacca agtttacggt
    64981 ggtcacgttc cttagcttct tcacgcattt gaaggtagtt tttcaagtct ttcttgtcaa
    65041 accaagctgt accgtagata cgttgcatca tagcgttgtc gctgtttcca cgccagtacg
    65101 caccagctac atggagaagg tggaagattt ggatacgacc tgttgatgga acatgaggtc
    65161 cacggcagag gtctacatat tcaccctgac gatagatagt caaaccgcct tcgtcttctg
    65221 agtgttcttc aatcaattcc aacttgtaag ggtcattttt gaagatttca cgtgcctcgt
    65281 ctttagtcac ttcttcacga atagatggga agttttcttt gacgattttt tgcatttctt
    65341 cttcgatacg aggaaggtct tcgttagaga tttgaccagc tgtgttgtca gtatcgtagt
    65401 agaaaccatc ttcgatggct ggaccaactc ccaagtgaat gtctgggaaa agacgacgag
    65461 ctgcttgggc gaacaagtga gctgctgagt gacgcaagat tggaagggca tcttcgtgat
    65521 caggtgtcac aatttcgatg cttccatctt cagtgatagc gcgagtagtg tcgatgagtt
    65581 tgccgttgaa tttaccagcc aaggcttttt tagctaggga attgctgata gattgggcaa
    65641 tttcaaaagt tgttacgcca gattcgaatt cacgaacagc gccatctggg aaagtaatgt
    65701 taatcatgat gttctccttt tttattattt catagtttct aagcattgat tttttatcag
    65761 cagactactt ccaagtccta acgttcaatt gcttttcttt atcagagagg aagttttcca
    65821 tttccgtcag aatgtctata tccaaacgtt gagaaagttc taatagtcac cagatatttt
    65881 ctgaaagttt ttgttccagt gtgtagggtg tttcatcata gtagcgtcct tgttttgtca
    65941 tcaccagtcg ttggaaattt ccaatatcat tagataaagc caagaggtct tcttctaccg
    66001 tccacttgga atcatgatgc ttaacttcca gttcgttata agcttgtcgg attgcccaac
    66061 tgcgctccac taattcttgc aactccataa ttagtatcct aataaaaaaa tgcgacatcc
    66121 tcgaaaggac gtcgcaacgt ggttccacct tcatttatgt acctcaaaag agagggacac
    66181 ctctgattgg ctctaacgtg gccaccgttt tatgttttca taaaaaactc aagagtagta
    66241 tcagtttaga cttcctatgc gtttccagca accacgcact ctctagtaga aagggactaa
    66301 gtgacttgtc tctatggatt attatagcat gattgtgaga tttttcaagg attttgtgaa
    66361 agttttttgt ttttcatttt ttgtagaata tgcttgatgc taataccaga atccatgccc
    66421 accagagcaa ctgtttcata gattagcaag taaattagta taaactcacc aaaggttatg
    66481 atagtaaagt aaaagagcag tccgttacca actaaccatc aaagtgagaa acggaaacgg
    66541 tagctataga gtaacgatac aatcaagatt accagaggtg taaagaagag aagattgttt
    66601 atatagtgta agggggtcag aaacaactag caagaacaac tcataaagtg gccaataaaa
    66661 gaataatatg accagatagt aggggagatg ggaatagaat ctacgcatga taatcacctc
    66721 gttttaaaaa aacagacaac ttagatctct tgctatgatt attatagcat atttaaaaca
    66781 agaaagtaaa tttgttgaca aagaagattt tttttcacta gaatcatggt tagttttctt
    66841 ggtagaaata ttttgataat aattaagcaa gactattgac attgattatt aagagtgtca
    66901 caattgctgt aactaaaata attacaacaa gagaggtata aaaaatgaaa ctagcagtta
    66961 ttgcagcaaa tggacaagcg gggaaagcaa ttgttgaaga agcagtcaaa cgaggacatg
    67021 aagtaacggc tattgttcgt tctgaaaaca aaagtcaagc tgagtctatt attaaaaaag
    67081 atttatttga gttgacaaaa gatgatctta ctggatttga tgctgttatt tcagcgtttg
    67141 gtgcttatac accagatacg ctaccgctcc atagcaaatc aatcgaacta tttaatcagc
    67201 ttcttgctgg aacacagaca cgttttctag ttgtaggggg agcaggaagc ctttatatag
    67261 atgaaacaaa aacgacacga cttttagata cgcctgattt tcctgaagaa tttaagccac
    67321 tagcaaaagc tcaagcggat gaatttgatc ttcttcgtac aaaaaataat ctcaactgga
    67381 cttttgtcag tcctgctgta gattttattc ccgatggtga aaaaacagga aactacattc
    67441 tagcaggaga aatttttact actaatggaa aaggaataag ccagattagt tatgcagatt
    67501 atgctattgg attggtagat gaacttgaaa aaggtcatca tataaaagaa cgtatctctt
    67561 tacttgaaaa ataataacta tgagagtatt aatgtttgac agaaaattta aatcttggta
    67621 aaatagggat tgtcgtaaag acaaataact tcttcttggt tacaggcatg ccaacctgtc
    67681 actcggatga agccaaataa aaaggagaaa catcatggca atctcaaaag agaaaaaaaa
    67741 tgaaatcatt gcacaatatg cacgtcacga aggtgataca ggttcagtag aggttcaagt
    67801 tgctgtcctt acttgggaaa tcaaccacct taacgaacac atcaaacaac acaaaaaaga
    67861 ccacgctact taccgtggat tgatgaaaaa aatcggtcgc cgtcgtaact tgcttgcata
    67921 cttgcgtaaa aacgacgtta accgttaccg tgagttgatc aactctctag gacttcgtcg
    67981 ctaattcaag atacaaaggc cgtcaaaagc acaaagcaaa aataggaaaa tctcctagaa
    68041 acttcagttt ctaggagatt ttatcttttt tgccaagtgc ttaggccgtg ttcaattgag
    68101 catatcttga taatgaagct actctaaatt gggtagcttt tttgcgttgt caccttacct
    68161 cgatatactc aagtataatc tttggttacg gttcctagca ctgtaaggta aaataaacca
    68221 gcttttctcc cttcggggag attttttttg tttcactgaa agtttcgtac gatcttcgcc
    68281 tcgtcgccta gtctataaac gatttatcta gcaagaatca tgatgctaag ggcgtcaaaa
    68341 atccgtatga aaatagggaa atgacacagt gttcgatgag cacaaggagt ttcatctttt
    68401 tcactaggat tttagcccgg gctcaaatca gctctctgac ttcagagggc ttttttattg
    68461 aggttttatc ggtaacaatt ttggagacta caaaaacctc aaacggtatc agctaattac
    68521 accataaagg tgcgcagtta ctcggctttt caagccgagt aactgtatgc aagcccctag
    68581 aagagcccac tctttacaaa gtaaagtata gtatgttata ctttacatgg aagtagtcac
    68641 tgaattccag ttagaaatta ctttgtaact acgttttgag gaggagtaaa atgctttcct
    68701 acgttcgaca ttacccacta gcgatagcta aattaatgtg tctgtgctct cctaaaatct
    68761 gctgatttat tactgactaa tacaggagtt ttttttatgg gacagacaat catatctgct
    68821 attggtgttt atatttccac cagtatcgat tatttaatta ttttaattat tttatttgca
    68881 cagctatcac agaataaaca gaaatggcat atttatgcgg ggcaatatct aggcacaggc
    68941 ttacttgtag gggcgagttt agttgctgct tatgtcgtta atttcgtgcc tgaagaatgg
    69001 atggttggat tgcttggttt aatccctatc tatttaggga ttcgctttgc aattgttgga
    69061 gaagatgcgg aagaagaaga ggaagaaatt attgaaagat tagaacaaag caaggcaaat
    69121 caactgtttt ggacagttac attgctgaca attgcgtctg gcggagataa tttaggtatc
    69181 tatatacctt attttgcttc gttagattgg tcacagaccc tcgtggcctt gcttgtgttt
    69241 gtaatcggca taattatctt ttgcgagatt agtcgggtgt tatcctctat tccgttaata
    69301 ttcgagacaa ttgaaaaata cgagcgaatc attgtgccct tagtattcat tctacttgga
    69361 ctatacatca tgtatgaaaa tggcacgata gagacttttc tgatcgtgta gatttttttg
    69421 tttcactagg attttagccc gagctcaaat cagctctctg attttcagag ggctttttca
    69481 ttgagtataa atggacaatc ttaaagttac tctattgtag agtggctttt gatttgatta
    69541 ggagattctt ataaatatag taaaatgaaa caaaaacagg acaaatcgat caggacagtc
    69601 aaatcgattt ctaaaaatgt tttaagaagt agaggtgtac tattctagtt tcaatttgat
    69661 atataaatga aaaccttagc tgtttggcca aggttcattt cttctatgca agttcttctc
    69721 ttttcttatc tgggttccag atgaagcttg cgataaagct aaagatgatg gttaggatag
    69781 cgaggataat agcaaggatg agggcaggga tgcggataaa ccaccagagt ggatttggtt
    69841 ttttatcatt gtgccattgt ttcgtttctt cgtccagacg ttggaattct gtttgaatac
    69901 gattggcgac tgtttcaatg ccttcatcat tcattttctt gatatctgag atatcgattg
    69961 gatttccaaa gttcatatcg acacgttcac ggctaatcaa gcccttcaaa gtcatgggac
    70021 cggtgtaggt aaccggcatg atacggacct tggccatttt ggcaatcagt gctgcgcccc
    70081 ccttgacatc gtttgagtgg cggctaccac ttggaaacat gatgagagag cggtcacttt
    70141 ttttgagaac gttgatagga tatttgatgg ctgaggcgct gggattttca cggtcgatgg
    70201 gaaaggcgcc acacatacga atccaccaac caaagatacg gttggtaaag agttcttttt
    70261 ttgccataaa gatgaactgt tttggcttgg tcgcaaaggc catataaaca ggatcccacc
    70321 aggtacggtg aggcgcaact aaaatataat tttcatcttg attaggaatt ttatcagtat
    70381 tatgatagtg agcattgcca ttgatggacc ataagagcaa tacaactaat ccacgcaaat
    70441 aagtataaaa catgcgatct ccttcgattg ttttcttgtt attattatac cttatcaaag
    70501 gagggctggc aaacttttcc cttgactaga tgcatatttg ggatgaaatt agaattctgt
    70561 taaaaaaaat gatataatag aatttatgga taaaaataag attatgggat taacccaaag
    70621 agaagtcaag gaaagacagg ctgagggttt ggtcaatgac tttaccgcat cagccagtac
    70681 cagcacttgg caaatcgtta aacgaaatgt ctttaccctt tttaacgctt tgaactttgc
    70741 cattgctttg gcccttgcct ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat
    70801 ctgctttaac gctttttctg ggattgtgac cgagctacga gccaaacaca tggtggacaa
    70861 gctcaatctc atgaccaagg aaaaggtcaa aaccatccgt gatggtcagg aagttgctct
    70921 taatcctgaa gaattagtgc taggagatgt cattcgtttg tctgcaggag agcagattcc
    70981 tagtgatgcc ttggttttgg aaggctttgc ggaagtcaat gaagccatgt taacgggaga
    71041 aagtgatttg gtgcaaaagg aagttgacgg cttacttttg tcaggaagtt tcctagccag
    71101 tgggtcagtt ttatctcaag ttcaccatgt cggtgcagac aactatgctg ccaaactcat
    71161 gcttgaggct aagaccgtta aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt
    71221 ggctggtttt actgggaaga ttatcattcc ctttggtctg gctctcttgc tggaagcctt
    71281 gcttttaaaa ggcctgcctc tcaagtcatc tgttgtaaat tcgtcgacag ctcttttggg
    71341 aatgttgcct aagggaattg cccttttgac cattacttcg cttttgactg cagtgattaa
    71401 gctaggtttg aaaaaggtct tggtgcagga gatgtactct gttgagacct tggcgcgcgt
    71461 ggatatgctc tgtctggaca agacgggcac catcacccaa ggaaagatgc aggtggaggc
    71521 tgttcttcca ctgacggaaa cttacggtga agaggctatt gccagcatct tgactagcta
    71581 catggcccat agtgaggata aaaatccaac agctcaagcc attcgccaga gattccaagg
    71641 tcaagtagtc tatcctatgc tctctaatct tcccttctcc agcgaccgca agtggggagc
    71701 catggagtta gaaggtttgg gaatagtttt cttaggggca cctgagatgt tgctggattc
    71761 tgaggtccca gaagccagag aggccttgga gagaggttca cgtgtcttgg tcttagctct
    71821 cagtcaggag aaattagacc atcacaaacc acagaaacca tctgatattc aggctctagc
    71881 cttgctggaa atcttggatc ctattcgaga gggagcggca gagacgctga actatctccg
    71941 ttctcaggaa gtggggctca agattatctc tggtgacaat ccagttacgg tatccagcat
    72001 tgcccagaag gctggttttg cggactatca cagctatgtc gattgttcaa aaatcacgga
    72061 tgaggaattg attgctctgg cggaggagac agcgattttc ggacgtgttt cccctcatca
    72121 aaagaaactc attatccaaa cgctgaaaaa agcgggtcat acaacagcta tgactgggga
    72181 tggagttaat gatatcctgg ctcttcgtga ggcggattgt tctatcgtaa tggcggaggg
    72241 agacccggca acccgtcaga ttgccaacct ggttctcttg aactcagact ttaatgatgt
    72301 tcctgagatt ctttttgaag gtcgtcgtgt ggtcaataac attgcccaca tcgctccgat
    72361 tttcttgata aagaccatct actcattctt gctcgcagtt atctgtatcg ccagtgcttt
    72421 actaggtcgg tctgaatgga tcttgatttt ccccttcatt ccaatccaga ttaccatgat
    72481 tgaccagttt gtggaaggtt tcccaccatt cgttttgact tttgagcgaa atatcaaacc
    72541 tgtcgagcca aacttcctca gaagatccat gcttcgtgcc ctaccaagtg ccctcatggt
    72601 cgtgtttagc gttctttttg tgaaaatctt tggaacgagt caaggttggt ctgagttaga
    72661 aatctcaact ctcctctatt atctcttggg gtcaattggt ttcttatccg tatttagagc
    72721 ctgcatgcca ttcactctat ggcgagtcct attgattgtc tggtcagtag gaggcttcct
    72781 agccacagct ctcttcccaa gaattcaaaa actgcttgaa attgcaacct taacagaaca
    72841 aacgttgcct gtttatggtg tcatgatgtt ggtctttaca gtgattttca tcctgactag
    72901 tcgctatcaa gctagaaaat aaagaaagac tgcaatctgt ggattgcagt ttttttaggt
    72961 acaagattgc cagccgaaat gtggtataat aagaggtaat agagttttgg aaagtgagag
    73021 aagatgattt caaagagatt agaattggta gcttcctttg tgtcacaggg ggctatttta
    73081 ctagatgtgg gaagtgacca tgcttatctg cctatcgagt tggttgagag aggccaaatc
    73141 aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt
    73201 gaggctcacg gcctaaagga gaaaatccaa gtccgtttag ccaatggctt ggcagctttt
    73261 gaagagactg accaagtgtc tgtcattacc attgctggca tgggtggtcg tttgattgct
    73321 aggattttag aagaaggttt ggggaagtta gctaatgtag agcgtttgat cctccagccc
    73381 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
    73441 gaaagcatct tagaagaagc tggcaagttt tacgagattt tggtggtgga agcaggacaa
    73501 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
    73561 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
    73621 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
    73681 gtgccccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
    73741 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
    73801 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
    73861 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
    73921 ccgtccgcaa aatcagattt acatcgacct gattaagcat gatatcgcag tttatgtcag
    73981 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
    74041 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
    74101 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
    74161 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
    74221 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
    74281 tgtctatatc actggcgaca tctactacca tactgctcag gatatgctgt ctgatggctt
    74341 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
    74401 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
    74461 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
    74521 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacttag
    74581 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
    74641 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
    74701 atttttatgt ggatttatta gctgatttag agaaatcagg acaagaaatc gacttttacc
    74761 agcgttcggg agtctttctt ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
    74821 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
    74881 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
    74941 gtggagcgag agtagatggc caactcttgg taactcgttt gctagaagcc agtcatgtca
    75001 agctggtcaa agaaaaagtg actctgacac cgttagcatc aggctaccag attggcgaag
    75061 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
    75121 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
    75181 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
    75241 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
    75301 tagatgaacc cttgctccaa caaatggagg aggccacctt gactcactat ctgattttgg
    75361 ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc ctacaccagt gatttctctc
    75421 ctttctttgg gcaggtgcct gacttaactg gtgtctatgc agccagtgga ctaggttcat
    75481 caggcctcac aactggtcct attattggtt accatttagc tcaactgatc caagacaagg
    75541 agttgacctt ggaccctgaa aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
    75601 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
    75661 actgctttga ggttgtggat agaactgacg aagtcagtaa ccatacccat ggcaaggcga
    75721 cgttgacgtg gtttgaattg gattttcgaa gagtataagc attttactga aattttatca
    75781 ggtagtttag gatggcaaat gacattccct gtcaaaaatg gtaaaataag aaaaaataat
    75841 ctgagaatcg aggaaaaaag atgcaagaaa agattttggt aactggtggt gccggtttta
    75901 ttggaaccca cactgttatt gaattgatcc aagcaggcca tcaagttgtt gtggtggata
    75961 atcttgtcaa tagcaatcgt aagagtttag aagttgttga aagaatcaca ggagttgaga
    76021 ttcctttcta tgaggcagat attcgtgaca cagataccct cagagatatt ttcaagcagg
    76081 aagaaccgac tggtgtcatt cactttgctg gtttgaaggc tgttggcgaa tcaacacgta
    76141 tccctcttgc ctactatgac aacaatatcg ctggaactgt cagccttttg aaagtcatgg
    76201 aagaaaacaa ctgtaaaaac atcatcttca gttcttctgc gacagtttac ggggatccgc
    76261 acacagtgcc catcttggaa gatttcccac tttcagtgac caacccatac ggtcgtacta
    76321 agctcatgct agaggaaatt ttgactgata tttacaaagc agactcagaa tggaatgttg
    76381 tcttgcttcg ttactttaac ccaatcggag cccatgagag tggtgatttg ggagaaaatc
    76441 caaacggtat tccaaacaat ctcttgccat atgtgactca agtagccgtt ggaaaattag
    76501 agcaagtgca agtgtttgga gacgattacg atacggaaga tggaacaggt gttcgtgact
    76561 atatccacgt tgtcgatttg gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag
    76621 gttcaggact aaacgtttat aaccttggaa ctggtaaagg ttactcagtt cttgaaatta
    76681 tccaaaacat ggaaaaagcg gtgggacgtc ctattcctta ccgcatcgta gaacgtcgcc
    76741 caggtgatat cgctgcctgc tactcagatc cagcaaaagc taaagcagaa ctcggttggg
    76801 aagcagaact cgacatcacc caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc
    76861 caaatggatt tgaagactaa gatgatgatt tcaatcatcg tcccttgttt aaacgaagag
    76921 gaagtacttc ctctttttta tcaggctctg gaagctttac ttccagattt ggaaacagaa
    76981 atcgagtatg tctttgtcga tgatggatcg agtgatggga ccttggaact cttaaaggcc
    77041 tatcgggagc aaaatccggc agcccattat atttctttct cgcgaaattt tggcaaagaa
    77101 gcagcccttt atgcaggctt gcaatatgcg acaggagatt tggtggtggt gatggatgca
    77161 gacctccaag atcctcctag tatgttgttt gagatgaaaa atgtactaga caaaaatgta
    77221 gacttggact gcgttgggac acggagaact agtcgggagg gagaaccctt ctttcgcagt
    77281 ttctgtgctg ttctctttta tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg
    77341 ggtgtccgtg attttcgtat gatgagaagg tctgtggtcg atgccatttt aagcttgact
    77401 gagtccaatc gtttttcaaa ggggctcttc gcctgggtgg gtttcaaaac ctactatttg
    77461 gactatccaa atgtcgaaag gcaggctggc aagaccagtt ggagttttag gcaactcttt
    77521 ttctactcca ttgaagggat tattaatttt tcagattttc ccttgattat agcctttgta
    77581 gctggtctcc tatcttgttt tctttctctg ctgatgacct tttttgttgt ggttcggacc
    77641 ctcattttgg gcaatccgac atctggttgg acctctctga tggctgttat tctctttctt
    77701 ggaggcattc aactcttgac cattgggatt ctcggaaagt atatcagtaa gatttattta
    77761 gagactaaaa aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca
    77821 gaaaaaaata aagtgaaaag actataattt tacatggaaa tatgctaaac tagagggagt
    77881 ggattatcgc cattgattta ggcttcctgg tttccaatca gggcgcgagt tgggcaattt
    77941 ttaacagcct ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca
    78001 tcgtaaaaac gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa
    78061 agcccacagg cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg
    78121 taataagaaa agtaaaaaaa acaaggagta aggtatggca aaagaaccgt ggcaagaaga
    78181 tatctatgat caagaagaat caagagcaga gcgtcggcat cgaaaccacg gaggggctga
    78241 taggatggct aatcgtattt tgacgatcct agctagtatt ttctttgtaa ttgtggtggt
    78301 gatggtcatc gttctcatct atctatcatc gggggggagt aatcgcacag cagccttaaa
    78361 agactttcat gattctgatg caagtgtagt acaaatctca tcttcaagca gttctcagcc
    78421 tgagcagagt tcagagctag aatctacttc tagtagttca gaagaagctg ctaatcctga
    78481 aggaacgatt aaagttctcg caggagaagg ggaagcagct attgccgctc gtgcaggaat
    78541 ctccattgct cagttagagg ccttgaatcc tgggcacatg gctacaggat cttggtttgc
    78601 taatccaggt gatgttataa aaataaaata ggagccgata tgaaaacaat tcaaattgct
    78661 attgatggtc ctgcttccag cggtaagagt acggtcgcaa agattattgc taaggatttt
    78721 ggattcacct accttgatac aggagctatg tatcgtgcag cgacctatat ggctcttaag
    78781 aaccaattag gagttgaaga agtcgaagcc cttctagcct tgttggacca gcatccaatc
    78841 agctttggac gttcagaaac tggagaccag cttgtttttg taggagatgt ggatattacc
    78901 catcctatcc gtgaaaatga agtgaccaat catgtttctg ctattgcagc aattcctgaa
    78961 gtgcgtgaga aactggtttc tctccaacaa gaaattgccc agcaaggcgg gattgtcatg
    79021 gatggtcgcg atattggaac tgttgtattg ccacaagcag aattgaaaat tttcctagta
    79081 gcttctgttg atgagagagc agagcgtcgt tacaaggaaa atattgccaa gggaattgaa
    79141 acagaccttg aaaccctaaa aaaggaaatt gctgcgcgtg actacaagga tagtcatcgt
    79201 gagacttctc ctctcaaaca agcagaggat gctgtctacc ttgatacaac tggtttgaac
    79261 attcaagaag tagttgaaaa aatcaaagca gaagctgaaa aaagaatgta aatgtagaaa
    79321 agccgataga ttgatatcgg tttttttcta aatttgtcaa aatgctgatt ttagggtata
    79381 atagttgctg ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaac
    79441 catgaacaat ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc
    79501 cctactggtt tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga
    79561 agaaggtctt gtcgctatcg atgccaacgg aaataaattg actgatggtg atacagtaac
    79621 tctcatcaag gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt
    79681 gaaaaatatc cgcatcgtag aaggcgacca caatatcgac tgtaagattg atggttttgg
    79741 tgccatgaaa cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa
    79801 cttgtatttt atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa
    79861 attactaggc atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg
    79921 gtaactattt ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa
    79981 aggccaagtc tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg
    80041 atttaccatt tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt
    80101 tgccactata tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt
    80161 caatacaaga tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt
    80221 gctcttttta atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc
    80281 ccttacttct ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt
    80341 atctttgttg cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga
    80401 aagtcatcct aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct
    80461 caaaacactg ttttgaacaa cctgcggcta gcttcctagt ttgctctttg attttcattg
    80521 agtataagat acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc
    80581 ttcttctttt cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag
    80641 aaagagattt catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt
    80701 tgattacctc cttttccatt tcgagtgctc taccagccat gtttgactat tatcagggtt
    80761 attctaagga acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt
    80821 tactgctaaa tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct
    80881 tgctgatttt atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct
    80941 ttggaacacg gcttctcttt ggtttgggtc ttgggatgat caatgccaag gccatttcta
    81001 ttatcagtga acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttctg
    81061 cagaggtcgt tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt
    81121 ggacagctat ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct
    81181 ttgtccctta tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt
    81241 taactcgaga aatgaaaggc ttgattttta ccttagctat cgaagcggca gttgtagttt
    81301 gtaccaatac agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg
    81361 atgcccagtt atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg
    81421 tgagtttttc tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta
    81481 cctttggctt ggggcaaatt gtgattgcct tgtcttcatc cttgtgggtg gtagtagcag
    81541 gaagtgttct ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct
    81601 ctgaacgaat tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta
    81661 gtttcggagc ctttacgacc ccatttgttc taggtgcaat tggcttacta actcacaatg
    81721 ggatgttggt ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt
    81781 acctacttca gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa
    81841 aatcaaagag catagttgat tgagtttgga atagtacgct gtagttgcta aaatatttct
    81901 agaaattaat ttgacttttc taatagagtt attcatatct tatttcaatc tactatagaa
    81961 agctagccgc aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt
    82021 tgaagagatt ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct
    82081 tgtttacaga ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt
    82141 cctatgatgg ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg
    82201 aagaaattga aaaaaccttg accagattaa ataaagggca aaccattact gttcacggtg
    82261 ctggtaggac agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt
    82321 atcagatgga tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg
    82381 atgtgatttc gattgagctt gtggcagatg attttcattg ccgttatgcc aaacatagca
    82441 agacctatga gtttattttg gatagaggac gtcccaaaaa tcctatgcgc cgtcactatg
    82501 ccacccactt tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag
    82561 agggaaccca tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc
    82621 gcaccatcac agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct
    82681 tttcaggaaa tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa
    82741 tcggtaacaa ccgcatgcca gtagagcaga ttgatctcat cttggagaag aaggacagga
    82801 aacttgcagg tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag
    82861 aataatcgta ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct
    82921 gatttggcta cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca
    82981 gccttgacag aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa
    83041 ttagatagct tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc
    83101 agtgtggctg agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg
    83161 gatcctgtct tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag
    83221 ttgattcgct ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta
    83281 ttatccggtc aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat
    83341 gatttaggag cgccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct
    83401 gtggatgtct tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc
    83461 caaaatgctg gtgcaggttg tacctttgcc tctagcattg ccagtcactt gattaaaggt
    83521 gataaacttt tgccagcagt agaaagctct aaggctttcg tttatcgtgc tattgcacaa
    83581 gcagatcagt atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt
    83641 atccctatta accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac
    83701 aggaattcta actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg
    83761 tgaaggagcg gtagtcggag gactagcaag tttcttgatt gacctcttat caggctaccc
    83821 tcagtggatg ttctttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa
    83881 aggaaaaagt cagtggttag gccttatttt agcaactatt gccatggtag gaggctacgc
    83941 cttgggttct actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt
    84001 catgcaaaat atggtaggga tgattgtagg atttattctt agtcaaagta tcaagaagat
    84061 taagtaatac tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa
    84121 cactgttttg agcagcctgc ggctagcttt ctagtctgat tttcattgag cataaagagg
    84181 ttgagtaaaa agtctttcaa ataagaaaaa cgcatagtat aggatgttga aatgatgaac
    84241 tgccccccaa aagttagaca gaaaaaatct aacttttggg gtgtttttat tatgaaacta
    84301 acttatgatg ataaagttca gatctatgaa cttagaaaac aaggatatag cttagagaag
    84361 ctttcaaata aatttgggat aaacaattct aatcttaggt acatgattaa attgattgat
    84421 cgttacggaa tagagttcgt caaaaaagga aaaaatcgtt actattctcc tgtttaaaac
    84481 aagaaatgat taataaagtc tgacatgaag gctag
//
LOCUS       DBEJZJ010000005        76709 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000005 DBEJZJ010000000
VERSION     DBEJZJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 76709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.05"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            84..740
                     /locus_tag="ACL3R8_000398"
     CDS             84..740
                     /locus_tag="ACL3R8_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR1313341.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            730..1053
                     /locus_tag="ACL3R8_000399"
     CDS             730..1053
                     /locus_tag="ACL3R8_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGR1313342.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            1157..1987
                     /locus_tag="ACL3R8_000400"
     CDS             1157..1987
                     /locus_tag="ACL3R8_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313343.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2141..2995
                     /locus_tag="ACL3R8_000401"
     CDS             2141..2995
                     /locus_tag="ACL3R8_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR1313344.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3095..4468
                     /locus_tag="ACL3R8_000402"
     CDS             3095..4468
                     /locus_tag="ACL3R8_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR1313345.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVSMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4461..5522
                     /locus_tag="ACL3R8_000403"
     CDS             4461..5522
                     /locus_tag="ACL3R8_000403"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR1313346.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5524..6216
                     /locus_tag="ACL3R8_000404"
     CDS             5524..6216
                     /locus_tag="ACL3R8_000404"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR1313347.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6246..6815)
                     /locus_tag="ACL3R8_000405"
     CDS             complement(6246..6815)
                     /locus_tag="ACL3R8_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR1313348.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6950..7564
                     /locus_tag="ACL3R8_000406"
     CDS             6950..7564
                     /locus_tag="ACL3R8_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR1313349.1"
                     /translation="MGRFLDFVFNRFFLGMIATALFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7542..9212
                     /locus_tag="ACL3R8_000407"
     CDS             7542..9212
                     /locus_tag="ACL3R8_000407"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1313350.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9224..10510
                     /locus_tag="ACL3R8_000408"
     CDS             9224..10510
                     /locus_tag="ACL3R8_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR1313351.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10562..11095
                     /locus_tag="ACL3R8_000409"
     CDS             10562..11095
                     /locus_tag="ACL3R8_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313352.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11173..11643
                     /gene="nrdI"
                     /locus_tag="ACL3R8_000410"
     CDS             11173..11643
                     /gene="nrdI"
                     /locus_tag="ACL3R8_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR1313353.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11936..13198)
                     /locus_tag="ACL3R8_000411"
     CDS             complement(11936..13198)
                     /locus_tag="ACL3R8_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR1313354.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIEKAG"
     gene            complement(13508..13966)
                     /locus_tag="ACL3R8_000412"
     CDS             complement(13508..13966)
                     /locus_tag="ACL3R8_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR1313355.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(13963..14403)
                     /locus_tag="ACL3R8_000413"
     CDS             complement(13963..14403)
                     /locus_tag="ACL3R8_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1313356.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14759..16708
                     /gene="mutL"
                     /locus_tag="ACL3R8_000414"
     CDS             14759..16708
                     /gene="mutL"
                     /locus_tag="ACL3R8_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR1313357.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17033..17500)
                     /gene="ribE"
                     /locus_tag="ACL3R8_000415"
     CDS             complement(17033..17500)
                     /gene="ribE"
                     /locus_tag="ACL3R8_000415"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR1313358.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17501..18706)
                     /locus_tag="ACL3R8_000416"
     CDS             complement(17501..18706)
                     /locus_tag="ACL3R8_000416"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR1313359.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18726..19361)
                     /gene="ribE"
                     /locus_tag="ACL3R8_000417"
     CDS             complement(18726..19361)
                     /gene="ribE"
                     /locus_tag="ACL3R8_000417"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR1313360.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19346..20446)
                     /gene="ribD"
                     /locus_tag="ACL3R8_000418"
     CDS             complement(19346..20446)
                     /gene="ribD"
                     /locus_tag="ACL3R8_000418"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR1313361.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20580..20694)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20851..21444
                     /gene="ruvA"
                     /locus_tag="ACL3R8_000419"
     CDS             20851..21444
                     /gene="ruvA"
                     /locus_tag="ACL3R8_000419"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR1313362.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21454..22017
                     /locus_tag="ACL3R8_000420"
     CDS             21454..22017
                     /locus_tag="ACL3R8_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR1313363.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22014..22691
                     /locus_tag="ACL3R8_000421"
     CDS             22014..22691
                     /locus_tag="ACL3R8_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1313364.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22828..23859)
                     /locus_tag="ACL3R8_000422"
     CDS             complement(22828..23859)
                     /locus_tag="ACL3R8_000422"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR1313365.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24114..24797)
                     /locus_tag="ACL3R8_000423"
     CDS             complement(24114..24797)
                     /locus_tag="ACL3R8_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR1313366.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24809..25753)
                     /locus_tag="ACL3R8_000424"
     CDS             complement(24809..25753)
                     /locus_tag="ACL3R8_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR1313367.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25885..28716
                     /gene="uvrA"
                     /locus_tag="ACL3R8_000425"
     CDS             25885..28716
                     /gene="uvrA"
                     /locus_tag="ACL3R8_000425"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR1313368.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28709..29770
                     /locus_tag="ACL3R8_000426"
     CDS             28709..29770
                     /locus_tag="ACL3R8_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR1313369.1"
                     /translation="MNKRVQAFLVKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29902..30300
                     /gene="spx"
                     /locus_tag="ACL3R8_000427"
     CDS             29902..30300
                     /gene="spx"
                     /locus_tag="ACL3R8_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR1313370.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30366..30935
                     /locus_tag="ACL3R8_000428"
     CDS             30366..30935
                     /locus_tag="ACL3R8_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR1313371.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31022..31288
                     /locus_tag="ACL3R8_000429"
     CDS             31022..31288
                     /locus_tag="ACL3R8_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR1313372.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31292..31711
                     /gene="ruvX"
                     /locus_tag="ACL3R8_000430"
     CDS             31292..31711
                     /gene="ruvX"
                     /locus_tag="ACL3R8_000430"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR1313373.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31727..32032
                     /locus_tag="ACL3R8_000431"
     CDS             31727..32032
                     /locus_tag="ACL3R8_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR1313374.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32492..33742
                     /locus_tag="ACL3R8_000432"
     CDS             32492..33742
                     /locus_tag="ACL3R8_000432"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR1313375.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33826..34284
                     /locus_tag="ACL3R8_000433"
     CDS             33826..34284
                     /locus_tag="ACL3R8_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR1313376.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     NTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESD
                     GDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34430..35962
                     /gene="cls"
                     /locus_tag="ACL3R8_000434"
     CDS             34430..35962
                     /gene="cls"
                     /locus_tag="ACL3R8_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR1313377.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36040..36183
                     /locus_tag="ACL3R8_000435"
     CDS             36040..36183
                     /locus_tag="ACL3R8_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313378.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36220..37758
                     /locus_tag="ACL3R8_000436"
     CDS             36220..37758
                     /locus_tag="ACL3R8_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR1313379.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMDVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37878..40085
                     /gene="nrdD"
                     /locus_tag="ACL3R8_000437"
     CDS             37878..40085
                     /gene="nrdD"
                     /locus_tag="ACL3R8_000437"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR1313380.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKGENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40097..40237
                     /locus_tag="ACL3R8_000438"
     CDS             40097..40237
                     /locus_tag="ACL3R8_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313381.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40281..40787
                     /locus_tag="ACL3R8_000439"
     CDS             40281..40787
                     /locus_tag="ACL3R8_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313382.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGLWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVKR
                     YWIEVANE"
     gene            40780..41370
                     /gene="nrdG"
                     /locus_tag="ACL3R8_000440"
     CDS             40780..41370
                     /gene="nrdG"
                     /locus_tag="ACL3R8_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR1313383.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41367..41984
                     /locus_tag="ACL3R8_000441"
     CDS             41367..41984
                     /locus_tag="ACL3R8_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR1313384.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42251..42559
                     /gene="rpsJ"
                     /locus_tag="ACL3R8_000442"
     CDS             42251..42559
                     /gene="rpsJ"
                     /locus_tag="ACL3R8_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR1313385.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42775..43401
                     /gene="rplC"
                     /locus_tag="ACL3R8_000443"
     CDS             42775..43401
                     /gene="rplC"
                     /locus_tag="ACL3R8_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR1313386.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43426..44049
                     /gene="rplD"
                     /locus_tag="ACL3R8_000444"
     CDS             43426..44049
                     /gene="rplD"
                     /locus_tag="ACL3R8_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR1313387.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44049..44345
                     /locus_tag="ACL3R8_000445"
     CDS             44049..44345
                     /locus_tag="ACL3R8_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR1313388.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44363..45196
                     /gene="rplB"
                     /locus_tag="ACL3R8_000446"
     CDS             44363..45196
                     /gene="rplB"
                     /locus_tag="ACL3R8_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR1313389.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45300..45581
                     /gene="rpsS"
                     /locus_tag="ACL3R8_000447"
     CDS             45300..45581
                     /gene="rpsS"
                     /locus_tag="ACL3R8_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR1313390.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45593..45937
                     /gene="rplV"
                     /locus_tag="ACL3R8_000448"
     CDS             45593..45937
                     /gene="rplV"
                     /locus_tag="ACL3R8_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR1313391.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45950..46603
                     /gene="rpsC"
                     /locus_tag="ACL3R8_000449"
     CDS             45950..46603
                     /gene="rpsC"
                     /locus_tag="ACL3R8_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR1313392.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46607..47020
                     /gene="rplP"
                     /locus_tag="ACL3R8_000450"
     CDS             46607..47020
                     /gene="rplP"
                     /locus_tag="ACL3R8_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR1313393.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47030..47236
                     /gene="rpmC"
                     /locus_tag="ACL3R8_000451"
     CDS             47030..47236
                     /gene="rpmC"
                     /locus_tag="ACL3R8_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR1313394.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47261..47521
                     /gene="rpsQ"
                     /locus_tag="ACL3R8_000452"
     CDS             47261..47521
                     /gene="rpsQ"
                     /locus_tag="ACL3R8_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR1313395.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47547..47915
                     /gene="rplN"
                     /locus_tag="ACL3R8_000453"
     CDS             47547..47915
                     /gene="rplN"
                     /locus_tag="ACL3R8_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR1313396.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47993..48298
                     /gene="rplX"
                     /locus_tag="ACL3R8_000454"
     CDS             47993..48298
                     /gene="rplX"
                     /locus_tag="ACL3R8_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR1313397.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48322..48864
                     /gene="rplE"
                     /locus_tag="ACL3R8_000455"
     CDS             48322..48864
                     /gene="rplE"
                     /locus_tag="ACL3R8_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR1313398.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48882..49151
                     /gene="rpsN"
                     /locus_tag="ACL3R8_000456"
     CDS             48882..49151
                     /gene="rpsN"
                     /locus_tag="ACL3R8_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR1313399.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49436..49834
                     /gene="rpsH"
                     /locus_tag="ACL3R8_000457"
     CDS             49436..49834
                     /gene="rpsH"
                     /locus_tag="ACL3R8_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR1313400.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50026..50562
                     /gene="rplF"
                     /locus_tag="ACL3R8_000458"
     CDS             50026..50562
                     /gene="rplF"
                     /locus_tag="ACL3R8_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR1313401.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50646..51002
                     /gene="rplR"
                     /locus_tag="ACL3R8_000459"
     CDS             50646..51002
                     /gene="rplR"
                     /locus_tag="ACL3R8_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR1313402.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51020..51514
                     /gene="rpsE"
                     /locus_tag="ACL3R8_000460"
     CDS             51020..51514
                     /gene="rpsE"
                     /locus_tag="ACL3R8_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR1313403.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51528..51710
                     /gene="rpmD"
                     /locus_tag="ACL3R8_000461"
     CDS             51528..51710
                     /gene="rpmD"
                     /locus_tag="ACL3R8_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR1313404.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51855..52295
                     /gene="rplO"
                     /locus_tag="ACL3R8_000462"
     CDS             51855..52295
                     /gene="rplO"
                     /locus_tag="ACL3R8_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR1313405.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52308..53618
                     /gene="secY"
                     /locus_tag="ACL3R8_000463"
     CDS             52308..53618
                     /gene="secY"
                     /locus_tag="ACL3R8_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR1313406.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53769..54407
                     /locus_tag="ACL3R8_000464"
     CDS             53769..54407
                     /locus_tag="ACL3R8_000464"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR1313407.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54524..54742
                     /gene="infA"
                     /locus_tag="ACL3R8_000465"
     CDS             54524..54742
                     /gene="infA"
                     /locus_tag="ACL3R8_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR1313408.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54767..54883
                     /gene="rpmJ"
                     /locus_tag="ACL3R8_000466"
     CDS             54767..54883
                     /gene="rpmJ"
                     /locus_tag="ACL3R8_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR1313409.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54901..55266
                     /gene="rpsM"
                     /locus_tag="ACL3R8_000467"
     CDS             54901..55266
                     /gene="rpsM"
                     /locus_tag="ACL3R8_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR1313410.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55284..55667
                     /gene="rpsK"
                     /locus_tag="ACL3R8_000468"
     CDS             55284..55667
                     /gene="rpsK"
                     /locus_tag="ACL3R8_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR1313411.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55710..56645
                     /locus_tag="ACL3R8_000469"
     CDS             55710..56645
                     /locus_tag="ACL3R8_000469"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR1313412.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56657..57043
                     /gene="rplQ"
                     /locus_tag="ACL3R8_000470"
     CDS             56657..57043
                     /gene="rplQ"
                     /locus_tag="ACL3R8_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR1313413.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57308..57574
                     /locus_tag="ACL3R8_000471"
     CDS             57308..57574
                     /locus_tag="ACL3R8_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR1313414.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57584..58921
                     /locus_tag="ACL3R8_000472"
     CDS             57584..58921
                     /locus_tag="ACL3R8_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR1313415.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59165..59857
                     /locus_tag="ACL3R8_000473"
     CDS             59165..59857
                     /locus_tag="ACL3R8_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1313416.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(59960..61605)
                     /locus_tag="ACL3R8_000474"
                     /pseudo
     CDS             complement(59960..61605)
                     /locus_tag="ACL3R8_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61595..62686)
                     /locus_tag="ACL3R8_000475"
                     /pseudo
     CDS             complement(61595..62686)
                     /locus_tag="ACL3R8_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62699..63820)
                     /locus_tag="ACL3R8_000476"
                     /pseudo
     CDS             complement(62699..63820)
                     /locus_tag="ACL3R8_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64407..65183)
                     /locus_tag="ACL3R8_000477"
     CDS             complement(64407..65183)
                     /locus_tag="ACL3R8_000477"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR1313417.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65305..66051
                     /locus_tag="ACL3R8_000478"
     CDS             65305..66051
                     /locus_tag="ACL3R8_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1313418.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            66064..67044
                     /locus_tag="ACL3R8_000479"
     CDS             66064..67044
                     /locus_tag="ACL3R8_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR1313419.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67239..67559
                     /locus_tag="ACL3R8_000480"
     CDS             67239..67559
                     /locus_tag="ACL3R8_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1313420.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67605..67913
                     /locus_tag="ACL3R8_000481"
     CDS             67605..67913
                     /locus_tag="ACL3R8_000481"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1313421.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67930..69228
                     /locus_tag="ACL3R8_000482"
     CDS             67930..69228
                     /locus_tag="ACL3R8_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1313422.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69379..71817
                     /locus_tag="ACL3R8_000483"
     CDS             69379..71817
                     /locus_tag="ACL3R8_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR1313423.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71836..72504
                     /locus_tag="ACL3R8_000484"
     CDS             71836..72504
                     /locus_tag="ACL3R8_000484"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR1313424.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            72522..73610
                     /locus_tag="ACL3R8_000485"
     CDS             72522..73610
                     /locus_tag="ACL3R8_000485"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR1313425.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            74065..76566
                     /gene="leuS"
                     /locus_tag="ACL3R8_000486"
     CDS             74065..76566
                     /gene="leuS"
                     /locus_tag="ACL3R8_000486"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR1313426.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT        23281 a        13993 c        16792 g        22643 t
ORIGIN      
        1 tatcttattt caatccatta tattaagaca atatgaggag aaagatgaaa gaaaaaggat
       61 tttaggaggg ggtgcaggca gtcatgccaa cggctcttgg ttatgtcagt atcggcctgg
      121 cctgtggaat tatcggtgcg ccctatgtga cacctgttga gatgggcttg atgagtctct
      181 ttgtttatgc tgggagtgcc cagtttgcca tgttggcact gattgtggtt caagctcctg
      241 tggcagctat tgctatgacg gtttttctaa tcaacttgcg tctctttttg ttgagtttac
      301 acgcatcgac ttatttccgt cataccagtc tttggtacaa tatcggtatg tctagtatct
      361 tgacagatga gacctatggc gttttgatgg gtgaattggc ccatacagac aaggtaaatc
      421 ctatgtggat gcacggaaac aatcttaaca gctatgtggc ttggtttgtg gggacagtag
      481 tcggaacggc tctgggtggc ctgctaccaa atccagaaat ctttggcttg gattttgccc
      541 tggttgggat gtttattggt atttttgctt cgcaatttca gattatgcaa agacggattc
      601 ctgtccgcaa tctgctcatt atcctagcag ttgttgcggt gtccttcttt ttgctcttga
      661 cagtggtgtc tcagtcacta gctgttctgt ttgcgacgct acttggttgt agcatggggg
      721 tggttttaga tggtcagtaa gtatctttta ttagcagtta ttttctctgg cttggtgact
      781 tggattctcc gtatgattcc cttcatctta gtcaagtata agggcttgcc tgcaatcgtt
      841 gagcgttttt tgaagttctt gcccgtttcc attatctttg ccttgattct ttcaagcgta
      901 gtgacaggta aggttgggag ccttcctcaa attaaatggc tagacttctt agccgtcttt
      961 ccaacagctt gggtagcctt tcgctaccgc aatctagtcg gtacggttct ctttggagta
     1021 gtcttgattg ccgtcttgcg tttggtcttt taaataagtc ataaagaaaa cttatcacag
     1081 agatagatat catataatgg cgtaattact ttttttctga taagattata aggtattcta
     1141 ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgcag cccttgctct
     1201 tgttgctgca ggtgtgcttg cggcttgctc aggtggtgct aagaaagaag gacaagcagc
     1261 tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aagccattta tctatgaaga
     1321 aaatggcgaa ttgactggtt atgagattga agtcgttcgc gctatcttta aagattctga
     1381 caaatatgat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg gtcttgacgc
     1441 tgaccgttac aatatggctg tcaacaatct tagctacact aaagaacgtg cggagaaata
     1501 cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtcgtgaaga aagatgactc
     1561 tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc aagccactac
     1621 atcagctaag cagttagaag catacaatgc tgaacacacg gacaacccaa ctatccttaa
     1681 ctatactaag gcagacttcc aacaaatcat ggtacgtttg agcgatggac aatttgacta
     1741 caagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt tggacaactt
     1801 gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc ttgctcaggg
     1861 tcaagatgag ttgaaatcat ttgtagacaa acgcattaaa gaactctaca aagacggaac
     1921 gcttgaaaaa ttgtctaaac aattcttcgg agatacttat ctaccagcag aggctgatat
     1981 taaataattt cttgaaatca tccattctga gtaagatggg tgatttctca gtttttaggg
     2041 atatagtttt aaactatata tctgattatc taataacaat ttgtgaaatc aaacaaattg
     2101 tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca aaaaatggct
     2161 tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg gaaactcaga
     2221 aaagaaagca gacaatgcaa caactatcaa aatcgcaact gttaaccgta gcggttctga
     2281 agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacggaatta ccttggaatt
     2341 tacagagttc acagactatt cacaaccaaa caaagcaact gctgatggcg aagtagattt
     2401 gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg gaaaagacct
     2461 tgtagcgatt ggagatactt acatctctcc aatccgcctt tactcaggtt tgaatggaag
     2521 tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa
     2581 tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct tgattaaatt
     2641 ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc caaagaactt
     2701 gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag ttgacgctgc
     2761 cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag cacttttcaa
     2821 agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga aaaaagattg
     2881 ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc acacagatga
     2941 cgtgaaaaaa gttatcgaag aatcatcaga cggtttggat caaccagttt ggtaataaga
     3001 aacagggagg tgggagagag aattccacct cttgcttttg tatagagcac ggagtgtaaa
     3061 gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg aacaagaaca
     3121 gattgaaaaa tttgaaaagg atcatgtagc ccagcattat tttgaggttt tacgtacctt
     3181 gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg caaattatct
     3241 gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct atacagcgcc
     3301 ctttgtcatg gcacatttca agagttcgcg tccagatgcc aagaccttga ttttctataa
     3361 ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc cttttacgct
     3421 ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg gtcatatcac
     3481 agctcgcttg agtgctttga gaaaatatat gcagcaccat gatgatttac ctgtcaatat
     3541 cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata agtatttgga
     3601 aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa
     3661 tgccttggaa cagctggaaa tttctggtgg caataagggg attgtgacct ttgatgccaa
     3721 ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggtgttgtgg aatcagctcc
     3781 ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta tcttggttga
     3841 aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc tagaaactta
     3901 tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc ctctcttaca
     3961 ggaggagcgg atggcctttc taaaacgttt ctttttcgag ccagcgctta atatcgaagg
     4021 aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag aagccagtgc
     4081 caagctagag gttcgtctgg ttccgggtct agaaccgcat gatgttctgg aaaaaattcg
     4141 gaaacaacta gacaaaaatg gctttgataa ggtagaatta tactatacct tgggagagat
     4201 gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt tggccaagaa
     4261 attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac ctatgcatac
     4321 ggtctttgat gccctagagg tatcaatggt tgcattcggt ctaggaaatg ccaatagccg
     4381 agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata tcgaattagt
     4441 agaggagctg attagaagct atgagtagag atattatcaa gttagatcag atcgatgtga
     4501 cttttcacca aaagaagaga accattacag cggttaagga tgtgaccatt cacatccaag
     4561 aaggggatat ctacggaatc gttggatatt ctggagcagg aaaatcaacc cttgtacggg
     4621 tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac gatgtgattt
     4681 ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa gatatcggga
     4741 tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat gtagcctttg
     4801 cccttaaaca ctctggactc agcaaggaag aaaagaaggc taaagtagct aagttgttgg
     4861 acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct ggagggcaaa
     4921 aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg
     4981 agtcaacttc tgcccttgac cctaagacaa ccaagcagat tttggccttg ttgcaagatt
     5041 tgaaccaaaa attaggcttg actgttgtct tgattacgca tgaaatgcag attgtcaaag
     5101 acattgccaa ccgtgtggcg gttatgcagg atgggcattt gattgaagag ggtagtgtgc
     5161 ttgaaatctt ctcaaaccct aaacaacctt tgactcaaga ctttatctca acagctacag
     5221 gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa
     5281 acagtctctt ggtgcaactc aagtacgctg gagcttcaac agacgagcca cttttgaatg
     5341 aattgtacaa gcattaccaa gtaatggcta atattctcta tgggaatatc gaaattctcg
     5401 atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca gcgttggcag
     5461 gtgcccaaga agctattcgc caagcaggtg tacaactaaa agtattgaag ggaggacagt
     5521 aagatggaat cattgattca aacctattta ccaaatgtct ataaaatggg ttgggctggt
     5581 caggcaggct ggggaacggc tatctactta actctttata tgacagttct ttccttcatt
     5641 atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc gccaggtggt
     5701 gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat ttttcgtgcg
     5761 gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca
     5821 agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtttttgc cttctttgcc
     5881 cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc ggctcaagcg
     5941 agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct tccagatttg
     6001 atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat ggccggtgcg
     6061 gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg ctacaatcac
     6121 gatgtgacca tcttggcaac catcgttatc attttgatta tctttgcaat ccaattctta
     6181 ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgtgtg gctcttttta
     6241 actgatcaga ttttctgggc aaatttttta ctcaaggctt gtccaatcaa ggcacccact
     6301 agggctccga tgacaatact tgcgataaat agaaggacag ttccaggggt tggagtgacc
     6361 atgatacggt cgatatattc ttgggatttt cctcttgcca gaagagtagc catataggct
     6421 ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa aataatgaaa
     6481 gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctactcc atctgctagg
     6541 aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag
     6601 agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt tgcgactagg
     6661 atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa catgtttcca
     6721 gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa gtaaagaact
     6781 gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat aattttttca
     6841 caattctcat tttatcatgg tttggtggga ttgtaaatgg atactagaag tttttgaaaa
     6901 cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca tgggtagatt
     6961 tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct tattttggct
     7021 attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca ccttgatgag
     7081 cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg cttggtctct
     7141 ttacaagcaa aattttgtct caagcaacct gattttctat agctttttag gtgtgggtct
     7201 agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca ttgttcattt
     7261 gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt atacagtatc
     7321 tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat tatccttgat
     7381 tggcatcttt atgagtctag cagctgtggc taaggttctc cttgggactg tgctacttgt
     7441 agcaattggt tattatatgc ctgccctgct attttttgta ggaattggga tgtggcattt
     7501 ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa
     7561 atagaatgaa gcagttttgg ctacatacgc ttctaagaac ctatagttca gtgatgatca
     7621 ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca cgtgaaaagg
     7681 aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt gaatattacc
     7741 atagagagtc aacccagata gctcaggctt tagttgaaaa tcaagctcgt atcgagggaa
     7801 tctataaata ctttagcctt agcatgccag actattttta ctggcaatta gagcggaaag
     7861 cttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat gttcgaaatg
     7921 attttgtaac tggggtggcc attgcttttc aagattacaa ggaagtctat gtttctacta
     7981 aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca ggaaatagtt
     8041 ttgccattcc ggtgtcagat ccagtgtcag atcaagattt aggagtgatt tacatctcct
     8101 tggatcctgc tgttttatac catgccattg ataatactag aggtcatact ccgatggcag
     8161 taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca gttgataagg
     8221 agagtgaaaa ttggctagtt ggcttaactt ctcatggata tcaggttcag gtggcagttc
     8281 ctaaaaactt tgttttacaa ggaacagtga ctagctctgc tttgattgtg ggtttgagcc
     8341 ttctctttat tgtcattctt tatctgactt tgaggcagac ttttgctaat taccaaaagc
     8401 aggtagtgga tttagtagaa tccattcaag tcattgctca aggcgaagag gggcgtcgga
     8461 ttgacatttc cgagaaagat caggaattgc tcctaatcgc ggagacgacc aatgatatgt
     8521 tggatcgatt ggaaaagaat atccatgata tttaccagtt agaactcagt caaaaagatg
     8581 ccaatatgcg ggccttgcag gcgcaaatca accctcactt catgtataat acgctggagt
     8641 tcttgcgcat gtacgcagtc atgcagagtc aagatgagtt ggcagatatc atttatgaat
     8701 tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc aaacaggaat
     8761 tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag tccattgcct
     8821 atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt accttgcaac
     8881 cgctggtaga aaattatttc gcgcatggtg ttgaccacag gcggacagat aatgtgatta
     8941 gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat aatggtagag
     9001 gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaga tattttgaac
     9061 accaagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta cacgagcgtt
     9121 ttgtgctcta ttttggagac cgctatgcca ttacgataga gtctgcagag caagccggtg
     9181 ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata aagtattatt
     9241 agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct ttgataagtg
     9301 ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat atgttcagga
     9361 aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag ggcttgatat
     9421 gattcgggag atgaaagaga tcttaccaga tgctgcttat atcctgctct caggttacca
     9481 ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt tggtcaagcc
     9541 tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc tcggcgagag
     9601 agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg ttagttattt
     9661 aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt ccttcaccat
     9721 tccctactat gtcttgggtc aagactggca gattttcatt tctgaccaac ccctagatgg
     9781 tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct ggaagctgaa
     9841 tgctgagaaa accctctttt acggctctgt aaatctgcag cagtctgaga gtctctttgc
     9901 ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga
     9961 gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga ttactaaaca
    10021 gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca aagctgatga
    10081 cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat tggttcctta
    10141 tatcaaggaa actctgagca gctttttcgg tcaataccgt atgaatgaaa atgtggtcag
    10201 tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg atatcagtaa
    10261 ggctctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa ccgattcgac
    10321 ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt tgctttcaac
    10381 tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg gatatttcta
    10441 taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac
    10501 tatactataa aatttgtatt cctttacaaa aggtgctata atattatcag gaggttctat
    10561 catgaaaaag aaaccaattt atctatgggt cttgctaatc ttgtctgccc ttatttcagt
    10621 tccgtctctg tttggaattg tgagtccctt gcctagtaaa gaagcccttc gtgctgctca
    10681 gaaacaagtt gcaggggtca atgctcagca attagaagac cagcttaatt atacctatag
    10741 agtagcagaa gcatctcatt ctatttttaa tgttgctttg attgtgctat ctactatttt
    10801 agtggtcgta gcgattgtct tccttgttcg taaaaatttg caatatgcaa actatactta
    10861 cgttggctat gttttgttag ctattattgg ttcgatttat ggctatgttg gtttacaaga
    10921 cgctgtgcag ttggttcaag atgagagcat gcgtttgaca gtgagtattg gttcaaaagc
    10981 tgttagcatt ttctatatcg tcatcaatgt tctcttccta gcccttgtct tctataagat
    11041 gtggcgacaa cagaaagcct tggcagagga agaggaaaca gaagagcttg cctaagtatt
    11101 gacaaaaaag aactatcaag atacaatctt ggtagttgtt ttttgattat agataaaatc
    11161 atggaggtac atatgaagac aatttcttta gtttatatta gtttgagtgg caacactgaa
    11221 agttttgtga cgcgcttgaa agactatctc ttgtcccagt acaaaaggat tgaggttcaa
    11281 aagattcata tcaaggattt ggtcaaggaa ggcaaaaatt tctatgaaat ggaccatccc
    11341 tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg gcgtggataa cggagatgtt
    11401 gagattttga cgacaccggt gggagatttt attgcctatg gtaacaatgc tagtaagtgt
    11461 tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc aatactgcct aacagccaag
    11521 caatacagtc aacgctttgg cttccctgta ttggctgact ttgaaatgcg aggcatgctg
    11581 gaagatatca aacatgtcgc agctattatc gcagatttgt atgagttgga aaaggagaat
    11641 taatactcaa tgaaaatcaa agagcaaact aggaagctag tcgcaggttg ctcaaagcac
    11701 agctttgagg ttgcagatag agctgacgtg gtttgaagag attctcgaat agtataaagt
    11761 tcttataaga ggtggttgaa gttgttcaac tgttttttga gtataaacag tctttaagaa
    11821 cgtaaaaaag cataagttca ggtcttcaaa accttgttct tatgcttttt atcatagaaa
    11881 tatttgctga attttctctt gaaatgaaac cttatcttca tctcgcgctt gtcccttacc
    11941 ctgctttttc gattgcgagt gcgtagataa agaagatggc gaagccaaag aggaaaatca
    12001 atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt tttgttttca cgcgttacca
    12061 aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa agatccaatc atggcaaagc
    12121 ggagcatggt tgaaacctga ccagcgaaga acttgataat gacgataccg atgatagcag
    12181 tgatggtcat ccagatgttc aaagatttac gattgtcctc tttttgactg attagcagtc
    12241 ggagagattc ctgattaacg cgagaatagc catcgataac agttataact gttccaaaga
    12301 tacagaggaa ggcaataaag gtaatcaagt aacgggacca ttcgccaaga acagaggcat
    12361 acatgcccac gaattgagag atgtatttgg ctgaagcagc ttcaaccgcc tgccctgtag
    12421 gatactgaat cagtgctccc agtgccacaa agaagacggc taggatagct gttccaatat
    12481 aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa gttgacggtc tttctctttt
    12541 cagctgacca aagtgaattg atggctgaaa tttcaatagg agccggcatc catcctagga
    12601 gggagacgat gaagggcaga gctgccattt gccaaggtgt cttctcgaca aaatcagaac
    12661 tgtattctgg atgcttgacc gctgctatga taactgccag aacagtcgca atggttaagg
    12721 cagacataat ccatttgacc atgccgtcta aaagtttgta gcctccaaag agtagcatag
    12781 cccaaatgat tgcaacgaga atgagggacc actgagtaat gctaagtcca atcattggga
    12841 aggcactggc gatgatagct gagcacagaa tggcaacacc agccgtgttg accatagccg
    12901 aaaagacatt gaggataaag aaaatccaga gatagagttt tcctttttcg gcataacctt
    12961 caaccaaagt ctttccagta tcagctgtgt attcagcacc aaaacggaaa aatggatatt
    13021 taaagacatt ggctaagatg accaagagaa gtagagacca accgtaagaa ccgccagctt
    13081 gagttgagga tacaatgtgg gaacctccaa cagcggcagt tgccattagg attccaggtc
    13141 ccattgcttt tagcttgctt gcccaggttg attgatttaa ggaaatagct tgcgacatga
    13201 taaatactcc tttttgaatt ttcagaataa tctgtatatg taatctatat tctacaaaaa
    13261 attttggaaa aatgcaagaa tattttgaaa aaagatagaa aatttacaaa gaaaatctga
    13321 aataactgtt atgatatagc atattgaaac tagaatagta cacctttgct tctaaaacat
    13381 tgttagaaat cgatttgact gtcctgatcg atttatcctg ttcttatttc atttcactat
    13441 agtaaggtgc agcaggataa agaaaaaccg agaagtttct ttctcggatt tgcttattat
    13501 gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt ttagcctctc
    13561 ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata atgagctgga
    13621 ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt tgctagtggg acaaagccag
    13681 ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca cggctgaata
    13741 agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg cagtagagca
    13801 agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga gagtagggat
    13861 ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag aggatgaggc
    13921 cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt ctaatttctc
    13981 cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt ttaagaaaat
    14041 ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat tgatgatttc
    14101 tgattgggaa atttggataa aattgcttgg caagagttta agaacctgat agagtcgcaa
    14161 atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct ctatatagaa
    14221 gcgctgaatc ttgccaatct caactagata gacctgatca tcgattttcc ctttgatttt
    14281 ttctctttgg tccagatttt ctgcgaactc gatgactttc tggactttat ctgtcggctg
    14341 aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta gttctacttt
    14401 cataaatttc tctccttgtt tttcatacaa aattaatctc acttcttgta cacctttatt
    14461 aatactcttc aaaaatctct tcaaaccacg tcagcgtcgt cttgccatag gatagttgtt
    14521 gactttgtca gttttatcta caacctcaaa acagtgtttt gaactgtctg cgcctagctt
    14581 tctagtttgc tctttgattt ttattgagta taccactatt ttactccctc tggcaaggga
    14641 ctttgtctat gtggagggat tgggctccta tgtggtggag cttttctgtt ctttctgaaa
    14701 tatggtataa tagcactaat taatttctag gaaaatagat acagaaaggg gctgaaagat
    14761 gtctcatatt attgaattgc cagagatgct ggcaaaccaa atcgcggctg gagaggtcat
    14821 tgaacgtcct gccagtgtgg tcaaagagtt ggtagaaaat gccattgacg cgggctctag
    14881 tcagattatc attgagattg aggaagctgg tctcaagaag gttcaaatca cggataacgg
    14941 tcatggaatt gcccacgatg aggtggagtt ggccctgcgt cgccatgcga ccagtaagat
    15001 aaaaaatcaa gcagatctct ttcggattcg gacgcttggt tttcgtggtg aagccttgcc
    15061 ttctattgcg tctgttagtg tcttgactct gttaacggcg gtggatggtg ctagtcatgg
    15121 aaccaagtta gtcgcgcgcg ggggtgaagt tgaggaagtc atcccagcga ctagtcctgt
    15181 gggaaccaag gtttgtgtgg aggatctctt tttcaacacg cctgcccgtc tcaagtatat
    15241 gaagagccag caagcggagt tgtctcatat cattgatatt gtcaaccgtc tgggcttggc
    15301 ccatcctgag atttctttta gcttgattag tgatggcaag gaaatgacgc ggacagcagg
    15361 gactggtcaa ttgcgccaag caatcgcagg gatttacggt ttggtcagtg ccaagaagat
    15421 gattgaaatt gagaactctg acctagattt cgaaatttca ggttttgtgt ccttgcctga
    15481 gttgactcgg gctaaccgca attatatcag cctcttcatc aatggtcgtt atatcaagaa
    15541 cttcctgctc aatcgtgcta ttttggatgg tttcggaagc aagcttatgg ttggacgttt
    15601 tccactggct gtcattcaca tccatatcga cccttatcta gcggatgtca atgtgcatcc
    15661 aactaagcaa gaggtgcgga tttccaagga aaaagaactg atgaccctgg tttcagaagc
    15721 tattgcaaat agtctcaagg aacaaacctt gattccagat gccttggaaa atcttgccaa
    15781 atcgaccgtg cgcaatcgtg agaaggtgga tcaaactatt ctcccactca aagaaaatac
    15841 gctctactat gagaaaactg agccgtcaag acctagtcaa actgaagtag ctgattatca
    15901 ggtagaattg actgatgaag ggcaggattt gaccctgttt gccaaggaaa ccttggaccg
    15961 attgaccaag ccagcaaaac tgcattttgc agagagaaag cctgctaact acgaccagct
    16021 agaccatcca gagttagatc ttgctagcat cgataaggct tatgacaaac tggagcgaga
    16081 agaagcatcc agcttcccag agttggagtt tttcggacaa atgcacggga cttatctctt
    16141 tgcccaaggg cgagatggac tttacatcat agatcagcac gctgctcagg aacgggtcaa
    16201 gtacgaggag taccgtgaaa gcattggcaa tgttgaccag agccagcagc aactcctagt
    16261 gccctatatc tttgaatttc ctgcggatga tgccctgcgt ctcaaggaaa gaatgcctct
    16321 cttagaggaa gtgggcgtct ttctagcaga gtacggagaa aatcaattta ttctacgtga
    16381 acatcctatt tggatggcag aagaagagat tgaatcaggc atctatgaga tgtgcgacat
    16441 gctccttttg accaaggaag tttctatcaa gaaataccga gcagagctgg ctatcatgat
    16501 gtcttgcaag cgatctatca aggccaatca tcgtattgat gatcattcag ctagacaact
    16561 cctctatcag ctttctcaat gtgacaatcc ctataactgt cctcacggac gtcctgtttt
    16621 ggtgcatttt accaagtcgg atatggaaaa gatgttccga cgtattcagg aaaatcacac
    16681 cagtctccgt gagttgggga aatattaaaa gtataaaaaa gtctgggaaa aattttcaaa
    16741 atcagaaaaa cgcataaaat caggtgttca aaaaccttga ttttatgcgt tttatcatag
    16801 aaatatttac ttcatttttt cctaattctt ttcgaaactc tttttaaacg acgtcagttt
    16861 tatcagtaat ctcaaaacag tgttttgagc taattttgcc agttttgtct gtaacatcga
    16921 agttgtgttt taccactctg cgactggttt cctagtttgc tctatgattt tcacagagta
    16981 ttaaattgcg attttgccaa gtttctttat tcgtctaaaa gtagagtctg ttctatgcgt
    17041 ctaatgtacg aattaggttg accatttcaa tagctccttg tgcacactca gaacccttat
    17101 ttcctgcttt agtaccagct cgttctatgg cttgttcaat tgtatctgtc gttagcacac
    17161 caaacataac aggaatttcg ctatttaaac tgatttgggc gattccctta gatacctcgc
    17221 tacatacata atcataatga cttgtattcc ctctaatgac agctcccaag cagataattg
    17281 catcatattt tttacttttt gccatttttg atgcaatcag tggtatttca aaagctcctg
    17341 gaacccaggc tacctctata tctttctcgt ttacattctc tcttttgaga ttatctagtg
    17401 ctccagataa taattttgaa gttataaatt cattaaatct cgctacaaca atacctattt
    17461 taatattgtt tgctactaaa ttaccttcat aagtgttcat ttatttttcc tccatattta
    17521 aaatgtgacc cattcgattt ttctttgttt ctaaataaaa actatcgtaa ggattggctt
    17581 ctatttcgat tgatattcta ctggaaatgg taattccata tttttctaac tgttcaacct
    17641 tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc cagatcttta agcatttgtg
    17701 ctccaatatg atattctctt aaatcacctt caaagcctaa tgcaagattg gcatcaagcg
    17761 tatccatgcc ttgatcttgt aaatgatagg cttttaattt attgataagt ccaattcctc
    17821 gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt ctcaacaatt attttcatag
    17881 ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc taaaacatct cctgttaaac
    17941 attcggagtg gacccgacat aatacattgg cttcatcctc tatgtttccc ataataagag
    18001 caagatgatg ttccccattt agtttatcta tatagctaat tgctttgaaa ttaccgtatc
    18061 tagtaggcat attgacagtt gaaactcgtt ctaccagctg atcatatgct tttctatatt
    18121 cttgtaattc tttgatggta attagtggaa tgttgtgttt cttcgagaac tgaattaaat
    18181 catctattct catcattttg ccatcatgat tcattatttc acaacatagg ccacactctt
    18241 ttagtccagc taattttaat aaatcaacag ttgcttctgt gtgtccattt ctttctagaa
    18301 caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg cctgcgaaaa tcagagggtg
    18361 ttatatcttc agctacacac atacgtgcgg tcagtcctct ctcctcggca gaaatacctg
    18421 tggtcgtttc tttataatca attgaaactg taaaagcagt cttatgatta tctgtattgt
    18481 tttcaaccat aggtgaaagc attaattgat tagctaaact ttcgctcata ggcatacaaa
    18541 ttaatccttt ggcataagta gccataaaat taacattttc tgttgtagct gcttgtgcag
    18601 aacaaattaa gtctccttca ttttctctat ccttgtcgtc tataacaaga acaagtcgtc
    18661 ccttctgcaa tgcttctaat gcttcttgta tttttcgata ttccattgac tgattatcct
    18721 ttctgctaaa atccattttg atataatagt tccttcgata tttctgattt tggagagtta
    18781 tccatcagtt tttgcacata tttacctaag atatcatttt caagatttac tgtactcccg
    18841 acttgtttac tcttaagaat ggtttgtttc aaggtatgag ggataacaga tactgaaaag
    18901 tttactttgg agactttagc gacagtcaga ctaatgccgt caattgtaat agatcctttt
    18961 tcaactatta aatctaaaat ttctttttgt gtgttgattt gataccatac agcattatca
    19021 tcttttttta ttgacgagat ttttcctgta ccatcaatgt gtcctgtaac gacgtgaccc
    19081 ccaagtcgac cgttgacaga taaggctctt tctagattca cctcacttcc atgttttaat
    19141 agagtaagag ctgttcgact ccatgtttca ttcattacat caactgtaaa ggattgatga
    19201 ttgaaatgag taactgtaag acagatacca tttactgcta tactatcgcc taaatggata
    19261 tccgttaata tttttgaggc tttaattgat agtttacaat tacgagagtc tttctgtatt
    19321 ctttcaactt ttccgatttc ttcaattatt cctgtgaaca tggataaatc acttcacttt
    19381 ctatgagata gtcatttcct atttgagaaa aagcataagg tttcaatcta atagcgtcat
    19441 ttggcaaaga aatgccttca cctccgacag gaaacttggc actgcctcca aaaatttttg
    19501 gtgcaatata tattttcagc tcatcaacaa tttgttgttc caaagcactc caattcatta
    19561 gactgccccc ttctagaact aggctatcaa tctgcatgtt tcctagatgt tgcattaaac
    19621 tcgataagtc tatatgattg ccttttttct ttatggaaag tatttcacag ccatgatttt
    19681 gatatagctt cattttattt ttgtcttcag aggaagtggc aatgtaagtt ttaatatcat
    19741 ttgctgtttt tacgatttta gaggtaagag gagttcgtaa atgtgtatcg catatgatac
    19801 ggataggatt tttcccttcc tccaatctac atgtcagcaa aggatcgtct tgaataacag
    19861 tattgactcc caccataatt gcactaacat ggtgtcgtaa ctgatgcaca tgctttcttg
    19921 cctcttcttc agtaatccat ttggattgat ttgttttagt ggctattttt ccatccattg
    19981 tcattgcata tttcataaaa acatagggta catgctgggt aatatacttt ctaaaacttt
    20041 ttattaagtt aagacactca ttttctaaaa ttccaacagt aacttgaaga ttattttcct
    20101 caagtatctt tactcctttt ccagatacaa taggattaca gtctaggctt ccaatgacta
    20161 ctcttgtaat accactatcg attatagcat ctatacaagg aggtgttttc ccgaagtgac
    20221 aacagggttc aagtgttaca taaagcgtcg ctccgacagg ggattctcta cagtttttaa
    20281 gagcatttct ctcagcatgt gagccaccaa aaaactcatg ataaccttgt ccgatgatgt
    20341 gattatcttt tacaataact gcgccgacca taggattggg attgacgtaa ccagcccctt
    20401 tttgtgccag ttttattgct aatttcatat attttgaatc gctcatctca ctacctccaa
    20461 aaaaatatac cttgaatagg agactactca aggcatacaa aagaaaactt atgcgattaa
    20521 caaaaatgct ctgaaatgac aagtaatcat ttcagagcac gcaaaaagca caaatatact
    20581 tttatcttct ttcatccaga ctatactgtc ggctttggaa tttcaccaaa tcatgccttt
    20641 cggctcgtgg gctataccac cggtagggaa ttgcaccctg ccctgaagat agttattcaa
    20701 ttacagatga ttatagtact taattttgaa tatgtcaaca gataaatacc gattgttttt
    20761 gatatactgt atttgtgata atcgattctc gctcctcgga taaagaaaat atgatatact
    20821 agataaacga aataagagag aaggaacact atgtacgcat atttaaaagg aatcattacc
    20881 aaaattactg ccaaatacat tgttcttgaa accaatggta ttggttatat cctgcatgtg
    20941 gccaatcctt atgcctattc aggtcaggtt aatcaggagg ctcagattta tgtgcatcag
    21001 gttgtgcgtg aggacgccca tttgctttat ggatttcgct cagaggatga gaaaaagctc
    21061 tttcttagtc tgatttcggt ctctgggatt ggtcctgtat cagctcttgc tattatcgct
    21121 gctgatgaca atgctggctt ggttcaagcc attgaaacca agaacatcac ctacttgacc
    21181 aagttcccta aaattggcaa gaaaacagcc cagcagatgg tgctggactt ggaaggcaag
    21241 gtagtagttg caggagatga ccttcctgcc aagatcgcag tgcaagcaag tgctgaaaac
    21301 caagaattgg aagaagctat ggaagccatg ttggctctgg gctacaaggc aacagagctc
    21361 aagaaaatca agaaattctt tgaaggaacg acagatacag ctgagaacta tatcaagtcg
    21421 gcccttaaaa tgttggtcaa ataggagcag agaatgacaa aacgttgttc gtgggtcaag
    21481 atgaccaacc cactctacat cgcctatcat gatgaggagt ggggccagcc cctccatgat
    21541 gaccaagcgt tgtttgagtt gttgtgtatg gaaacctatc aggcaggcct gtcttgggaa
    21601 acggtactca acaaacgcca agctttccga gaagcctttc atagctatca aattcactca
    21661 gtcgcagaga tgactgacac tgaattggaa gccatgctgg agaatccagc tatcattcga
    21721 aatagagcca agatttttgc tacacgcgct aacgcccaag cctttctaca gttacaggca
    21781 gagtacggct cttttgatgc ctatctttgg tcttttgttg aggggaaaac tgtcgttaac
    21841 gatgttcctg attatcgcca agccccagct aaaacaccct tatctgagaa attagccaaa
    21901 gatctcaaaa aacgagactt caagttcaca ggcccagtcg ccgtattgtc ttttctacag
    21961 gctgcagggc tagttgatga ccacgagaat gattgtgagt ggaaaggtct taaatgatgt
    22021 ctaacaaaaa taagggaatt ctgatttttg cgattctcta tacagtcctc tttgtgtttg
    22081 atggcgttaa attgctggct tctttaatgc catctgccat tgcaaattat cttgtttatg
    22141 tagttttagc tttatatggc tccttcttgt tcaaggatag attgatccaa caatggaagg
    22201 agattagaaa gactaaaaga aaattcttct ttggagtctt aacaggatgg ctctttctca
    22261 ttctgatgac tgttgtcttt gaatttgtat cagagatgtt gaagcagttt gtgggactag
    22321 atggacaagg tctaaatcag tctaatattc aaagtacctt tcaagaacaa ccactactga
    22381 tagctgtttt tgcttgtgtc attggacctc tggtagaaga attatttttc cgtcaggtct
    22441 tattgcatta cttgcaggaa cggttgtcag gtttactaag cattattctg gtaggacttg
    22501 tttttgctct gactcatatg cacagtttgg ctctatcaga gtggattggt gcagttggtt
    22561 acttaggtgg aggccttgcc ttttctatta tttatgtgaa agaaaaagag aatatctact
    22621 atcccctact tgttcacatg ttaagcaaca gcctctcctt aatcatttta gctatcagta
    22681 tagtaaaatg aaatgagaac aggacaaatc gatttctaac aatgttttag aagtagaggt
    22741 gtactattct agtttcaata tactgtaata tgtgatgaaa atgccagtaa tgataccgag
    22801 aaaaaagctg agaaactttt cccagcttta tttgttatag tcaaagagaa tgacttgttc
    22861 ctgtgcatct acatgagcat ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc
    22921 gacattcaga ttatagacaa tcgggatatt gctgtcaatg atatccaata gtgcctcttt
    22981 atagtcgtca tggaaagttt catccatagg ttttccgacc aagagtccat tgatgaccgc
    23041 gaatatgcca gtgtccttta aagttagcaa catctttttg aagtcttctg gcttaggctt
    23101 ttcttcgctt gtttcgagca agaggatttt cccttcccag tctgacaagt cagggaaaag
    23161 tttgtatttt tggcagagtt ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta
    23221 gagggattcg aggcaaccac cgaggatttt cccctcgaac tgagcacttc cttgcaacaa
    23281 gtcaaaacct gtatttgtat gactgacacg aggtgttccc agggccgtgg gactaaaatc
    23341 agttcgttcc tcataccaaa cgtcactagg gcggatttct gaaattcttc ccgtctcaat
    23401 caattcttta aagtagtgaa ggctataggc tagcatttct ttgtctaatt cacaaatgtc
    23461 tgctaaaaag gattgaccat aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt
    23521 catggttgta tccgagaagc caagaaaaat tttttgtttg ataacctttt ggagttggtc
    23581 attttcaaaa agataaggta gcaagcgata ggtatcgtct ccaccgatgg cacataggat
    23641 catgtcgatg ctatcatcag aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg
    23701 gtccttgata aagtctaatc cttttaacga atggggcaaa aagatgggat tgagtcccag
    23761 atccttgaga cgttggatac ccaagtccac ttcgtgtttg acaaaatcct ctccgataat
    23821 gccactagat aaactaacaa taccaatagt agaaaccata tctcatcctc ctagaaatag
    23881 attgagccta ttttatcaca aaatataaga gaaagctatg tgggatttca gaagaatact
    23941 tttaatactc ttcgaaaatc tcttcaaacc acgtcagttt tatctgcaac ttcaaagctg
    24001 tgctttgagc aacctgcagc tagcttccta gtttgctctt tgattttcat tgagtacaac
    24061 tcaaaaaagt aagtgaaaaa gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct
    24121 tgatagcgtg ttggtcctgc acttgcacta cggatattca agcgtttctt gagatagaag
    24181 cgaagggcta ggagggctgc tccaataata gctagtggca atggatccag tactgggtta
    24241 aggctagctg gtaggaagct tgttgcaaag aagacaagca accaaaggaa catagaagct
    24301 aggataacta gtacagattt ccagaaaggt ggacgttgac tgcgatccat atctggtcca
    24361 tagtattggt aaacaaagta gtacatcaag tagaaggcaa atccaccaac cagtccaact
    24421 aatagaagag taatcaatcc atagccgaaa gcttgatctg ccgcaaagaa ggttgtgagg
    24481 gcgctgacaa gggcaaagag gctagtgatg aaaagagctg agtccataat catcagtttt
    24541 ggatcatcat tttcttttgg atgctctttt tcgtactgct ctttgacagt gaagctatga
    24601 gcccaatgag ttggtgcgcc gtatagggaa cgggcagttg tacctttaga ttgctcctca
    24661 aggatttggg gaatgacttc ctcaaaaata gtctggattt cagcgtctgt tttcccatct
    24721 ttgatgaatt gttgggtagc aatgtggaca aactcttggt ttttcttagt taatttttgt
    24781 agatcaattt gagacatagg aactcctctt agaaccattt tttatggatg agatagagag
    24841 tgagcgagac actcatagca aaggcgataa agacgattaa ccagaaggca tttggctctc
    24901 cgtttagggg aatttcatta tccttaaagt tcatcccgta ggcagaaaag accatggttg
    24961 ggatggacat gacgatggtc acaagggcca aggttttcat gatgttgttc tggttgttag
    25021 aaatgataga ggcaaaggtc tctgtcatag aatgcaagac gtttccataa atatctgcca
    25081 tctcgatggc ctgttgggtt tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt
    25141 atttcttgat attgctggtt gaactggtca atttcttaat cacgcgctca tttgttttga
    25201 gggaggcctt gaaatagacg atagtttttt ccaattccat gagctcaatc aattcttcat
    25261 tacgagttga ttgatgcagt tgactttcga tttgttcact cttgcggtcg attgaacgaa
    25321 gggctgttag gtaaagctct gcattgcgat aaagaatttg aaagataaaa cgtgaacgca
    25381 tgaaggtata gaaattacgc aatcgacggt tgataaagac atcaaggaca ggtagtggtt
    25441 ccaaacacgt agtgataatg gtttcctcag tgatgataat accaagcggg atggttacgt
    25501 agtaggtgcg gttatttctt tcctccgtga ccggcacgtc tacgataatc agggtatact
    25561 cgtcttcaat ggtaatacga gacatttctt ccgcatcgag cggtgctcga aggtcggcaa
    25621 tatcaatatc gaaggtgttg gcgatttcga gtgattcatt ttgagtcgga ttgacgagat
    25681 tgatccaagt acccggttca agcgtatcga tctctttaaa ttcagttgtt gtagagagaa
    25741 aaacttgttt catatccctt atcctttctc atttttcaga ttttttcaca ctgtactatt
    25801 atactacaaa atcggccttt tgggtaatag aatctcactt tttttggtat aatggtaagc
    25861 aataatggac taggaagaac aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc
    25921 cataatttaa aaaatattga tgtggagatt ccgcgagaca agttggttgt cgtgactggc
    25981 ttgtcaggtt cagggaagtc cagtctggct tttgatactc tctatgcgga gggacaacgt
    26041 cgctatgtag agagtttgtc cgcctacgct cgtcagttct tgggaaatat ggaaaaacca
    26101 gatgtagatg ccattgatgg tctcagccca gctatttcca tcgaccagaa aacgactagt
    26161 aaaaatcctc gctcgacggt gggaacgacg actgaaatca atgactatct gcgtctcctc
    26221 tacgcacgtg tggggacgcc ttactgtatc aacggacatg gagctatcaa tgcttcttct
    26281 gtggagcaaa tcgttgataa ggttttggag ttacctgaac gccagcgctt gcagatcttg
    26341 gctcctgtca tccgcaagaa aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa
    26401 gacgggtatg ttcgtgttcg tgtggatggg gaagtctatg atgtgaccga agtgccagag
    26461 ttgtctaaga gcaagcaaca caatatcgat gtcgtggttg accgtattgt tatcaaggag
    26521 ggcattcgta gtcgtctctt tgattccatt gaggctgccc ttcgtattgc agaaggttat
    26581 gtcattatcg acaccatgga cgattcggag ttgctcttct ctgagcatta tgcctgtcca
    26641 gtttgtggtt ttactgtccc agagttagag cctcgtctct tctctttcaa tgctcctttt
    26701 ggctcttgta gtgagtgtga cggcttgggc atcaagctgg aggtggatac tgatttggta
    26761 gtgccagatg ccagcaaaac cttacgtgag ggagcgctag caccttggaa tcctatctca
    26821 tccaactact atccaaacat gttagagcag gccatgaaag tctttggagt ggctatggat
    26881 aagccttttg aggacctgtc agaagaagat aagaacttga ttctctatgg gtcagatggt
    26941 aaggaattcc atttccacta tgagaatgaa tttggtggcg tgcgcgatat cgacattccg
    27001 tttgagggag ttatcaataa tatcaaacgt cgttaccatg aaaccaatag cgattacact
    27061 cgcactcaga tgcgtctcta catgaatgag ctgacctgcg gaacctgtca aggctatcgt
    27121 ctcaatgacc aggccttgtc tgtccgtgtg ggcggccagc aagggccaca tattggagaa
    27181 atctcagacc tgtctatcgc tgaccacttg gacttggtga gccagttaac tttgtctgaa
    27241 aatgaagcca tcattgctcg tcccattctc aaggaaatca aggatcgttt gaccttcctt
    27301 aataatgtgg gtcttaacta tctaaccctg tcacgttcag caggaaccct ttcaggtggg
    27361 gaaagtcagc gcattcgttt ggcaacccag attggttcca acctatcagg cgtcctctat
    27421 atcctagacg agccgtcaat cggtcttcac cagagggaca atgaccgcct gattgccagt
    27481 ctgaaaaaga tgcgtgactt gggcaatact cttatcgtgg tggaacacga cgaagatacc
    27541 atgcgtgaag ctgattatct gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag
    27601 attgttgcag caggtacacc taagcaagtg gctcgcaaca gcaagtctat cacaggtcag
    27661 tacttgtcag gcaaacgtgt catcccagta ccagaagagc gccgtgtcgg aaatggtcgt
    27721 tttattgaag tgataggagc gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca
    27781 ctaggaaaat ttatcgcagt gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac
    27841 agcattctca aaaaagccat tgctcagaag ctcaaccgta attcagacaa acctggtaag
    27901 tttaagacta ttacagggat tgagcatgtc gaccgtttga ttgatattga ccagagccct
    27961 atcggacgga cgccgaggtc taacccagct acctatacag gagtttttga cgatatacgt
    28021 gacctttttg ctcagacaaa tgaagccaag attcgaggct acaagaaggg gcgcttcagt
    28081 ttcaacgtca agggaggtcg ctgtgaagct tgctcaggtg acgggattat caagattgag
    28141 atgcacttct tgccagatgt ttatgtggct tgtgaagttt gccacggaac ccgctataac
    28201 agtgaaaccc tagaagttca ctacaaggaa aagaatattt cgcaggtctt ggatatgacg
    28261 gtcaacgatg cggtagaatt tttccaacac attccgaaaa ttcaacgcaa actccagacc
    28321 atcaaggatg tagggctagg ctatgtgacc ttgggacagc cagctaccac cctttctggg
    28381 ggagaagccc aacgtatgaa gttagctagc gaactccaca aacgctcgac aggaaaatct
    28441 ttctacattc tggatgagcc gacgacaggg cttcatacag aggacattgc tcgcctgctc
    28501 aaggttttag ctcgctttgt agacgatggc aatacagtcc tcgtcatcga gcacaatctg
    28561 gatgttatca agacggcaga ccatatcatt gacttgggac ctgagggcgg tgtcggtggt
    28621 ggaaccatca tcgtaacagg aactccagaa gaagtagctg ccaacgaagc cagctataca
    28681 ggacactatt tgaaaggaaa gttacatcat gaataaacgc gtacaagcat ttctagttaa
    28741 aatgcaagaa aaagaactag atggtgtcat catcaacaat cttaaaaacg tctattattt
    28801 gactggtttt tggggctcaa acggaacagt ctttatcagc cgtgaccgtc aggtcttagt
    28861 gacagactct cgctatatca tcgcagctaa gcaagaaacc agtggttttg agattgtggc
    28921 tgatcgtgat gaattggctg tcattgcagg aattgttaag gacatgggct tgactcgtat
    28981 cggttttgaa gatgagattt cagtgtctta ttaccaccgt atgcaggcag cttttgcagg
    29041 tttggacttg tttccgcaaa ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc
    29101 agagattgca gcgattcgca aggcttgttc tatctcagac caagctttcc gcgatgcgct
    29161 tgactttatc aaaccaggaa aaactgaaat tgagattgcc aacttccttg acttccgcat
    29221 gcgtgagttg ggagcatctg gcttatcttt tgatacgatc ctagctagcg gtatcaattc
    29281 ttctaaaccc catgcccatc caatgcacaa accagtggag ttgggagaag ccattaccat
    29341 ggacttcggc tgtctctatg accactatgt cagtgatatg acccggacta tctatctagg
    29401 gcatgttagc gatgagcagg cagagattta caatacggtt ctaaaagcta accaagcctt
    29461 gattgaccaa gctaaggcag gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat
    29521 tatcattgag gcaggttatg gcgactactt tactcacggc attggccacg gtattggtct
    29581 ggatatccat gaggaaccct actttagcca gacttctaca gaaactatta agacaggtat
    29641 ggccttgacc gatgaaccag gtatctatat cgaaggcaaa tatggcgttc gtatcgagga
    29701 tgatatcctg attacagaga caggttgtga attattgacc ctagctccaa aagagttgat
    29761 agtcatttag ttgtttgtca agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat
    29821 taaaaatagg tcgcaagtcg gatgtttttt atggtataat agactaaact gatagtaaca
    29881 tgtagcgaaa ggggtaggta catgattaaa atttatacag tctcaagttg tactagctgt
    29941 aaaaaagcaa aaacctggct caatgcccac cagttaagtt ataaagaaca aaaccttggt
    30001 aaagaaggaa ttacgagaga agaattactg gatattctaa ccaaaacaga taacggaata
    30061 gccagcatcg tttcgtctaa aaatcgctat gccaaagccc ttggagtgga tattgaagat
    30121 ttgagtgtca atgaagttct caatctgatt atggaaacac cgagaatttt aaagagccca
    30181 atccttgtag atgaaaaacg cctgcaagtt ggctacaagg aagacgatat tcgtgccttc
    30241 ctaccacgct ctgtccgtaa tgtagaaaat gcagaagcac gtttacgtgc agctctataa
    30301 acatcaaggc tgggagcaat tcccagtctt attctatttt aatttcaaaa agaaagaaga
    30361 aagaaatgaa aaaaatagtt cttgttagtc tagctttcct ttttgtcctg gttggttgcg
    30421 gacagaaaaa agaaactgga ccagctacaa aaacagaaaa ggatacgctt cagtcggcat
    30481 tgccagttat tgaaaatgcc gagaagaata cagttgtaac caagactttg gtcttgccca
    30541 agtcagatga tggtagccag caaactcaaa ccattacata caaggacaag acttttttga
    30601 gcttaacgat tcaacaaaaa cgtccagttt ctgatgagtt gaagacttat attgaccaac
    30661 atggagtgga agaaactcaa aaagctcttc ttgaagcgga ggagaaggat aagtctatca
    30721 ttgaagctcg taaattggta ggtttcaaac ttgaaacaaa actattgagc gcaacggaac
    30781 ttcaaacaac gactagtttt gattttcaag ttctggatgt caagaaggct tcccagttgg
    30841 aacatctgaa gaatattggt ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt
    30901 cagacagatt ggcaaatggt gcgacagaac agtagaaaat ccaaataaat agactgcctg
    30961 aattgtagaa ggtaaggaat tatgctataa tggtactatt ctaaggaaag agggtgttag
    31021 aatgggattt actgaagaaa cagtacgttt taaattggac gattccaata aaaaagaaat
    31081 tagcgaaact ttgacagatg tttatgcttc gttgaacgat aagggttaca acccaattaa
    31141 ccaaatcgta ggttacgtat tgagtggaga ccctgcctac gttcctcgtt ataataatgc
    31201 acgaaatcaa atccgtaagt atgagcgtga tgaaatcgtt gaggaattgg ttcgctacta
    31261 cctcaaagga caaggagtcg atctataacc tatgagaatt atgggattgg acgtcggttc
    31321 aaaaacggta ggggtggcga ttagcgatcc gcttggtttt acagctcaag ggcttgaaat
    31381 catccagata aatgaagaac aaggccaatt tggttttgac cgcgttaagg aattggttga
    31441 tacttacaag gtggaacgat ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg
    31501 accgcgcgta gaagctagtc aagcctacgg agcaaagcta gaagagtttt ttggtttacc
    31561 agtagactat caggatgaac gcttgacaac agtggctgct gagcgcatgt tgattgaaca
    31621 agcagatatc agtcgcaata agcgcaagaa agtcattgat aagttagcag ctcagctgat
    31681 tttacaaaat tatttagata gaaaatttta atataaagga gaggctatgt cacacgatca
    31741 taaccacgac cacgaagaac gtgaactaat cacactagta gatgagcaag gaaatgaaac
    31801 cttgtttgaa atccttttga caattgatgg aaaagaagaa tttggtaaaa actatgttct
    31861 tctagtacca gttaacgcag aagaagacga agacggacaa gttgaaatcc aagcttactc
    31921 attcatcgaa aacgaagatg gaacagaagg cgaattgcaa ccaatcccag aagactcaga
    31981 agacgaatgg aacatgattg aagaagtctt caacagcttt atggaggagt gatacagtct
    32041 gggagactgt atcagcccaa ctcccagaaa tggggaagag ttggaacatc cagtggatgt
    32101 ttttagccca gttcctttaa ataagagaga actggtaagt ccgggggacg tttttagcct
    32161 gacgctaaaa ataaaaacag tcagtaagtt cgggggatgt tttagcccag ctccttgaaa
    32221 taagatagag ctggtaagtc tgagaaactg tatcagccca actcccagaa atggggaaga
    32281 gttggaacgt ccagtgaaca tttttacccc aactcttaga aattgagaag agttggaaca
    32341 tctagtggat gtttttagcc catattcaca ttcatagtag ctagttatta gctaaccagg
    32401 taagaggtcg ggacgaaaat cctggccttg tttttattag taaccatact ttaatgcgat
    32461 aattgattgg acttttgtca aggagatgtg tatgtttgaa gtagaagaat ggctccatag
    32521 tcggattggt ttgaattttc gatcaggttt gggccgaatg cagcaagcgg tggatttgtt
    32581 aggaaatcct gagcagtctt accctattat ccacgtaaca gggactaatg ggaaaggatc
    32641 taccattgct tttatgaggg aattatttat ggggcatggc aaaaaagttg cgacctttac
    32701 ctcccctcat atcgtctcta tcaatgaccg aatctgcatt aatgggcaac ctatagcaga
    32761 cgcagacttt atccgtttga ctgatcaggt caaggagatg gagaaaacgc ttctgcaaac
    32821 tcctgcccag ttgtcctttt ttgaattgct gaccttagtt gcttttcttt attttaggga
    32881 gcaagaggtg gatttggttt tattagaagt gggaattggt ggcttacttg acacgaccaa
    32941 tgtggtaact ggagagcttg ctgtcatcac ctccattggg cttgaccatc aagaaacctt
    33001 gggtgatagt ctagaagcaa ttgcagagca gaaagctggt attttcaagg ctggtaaaaa
    33061 ggcagtgatt gcgaaattgc ctccagaagc tagacttgtc tgtcagaaaa aagctgaatc
    33121 tttagctgtt gacctttatc aggcaggtca agatttttca gtgctgaatg gtgatttttc
    33181 aagctcttta ctaaatcttt cacagctgaa cataggctta gaaggagcct atcagcagga
    33241 gaatgcggcc ttggcgttgc aaacttttct tctttttatg ggagaaagaa aggaagctat
    33301 tgatgaacag gctgtaagaa aggccttgga acagacccat tgggctggtc gcttggagcg
    33361 tattcgccca cagatttact tggatggtgc tcataacctc cctgccttga ctcgcttggt
    33421 tgagtttatc aaagaaaaag agcaggaagg ctatcgacct caaatcctct ttggatcctt
    33481 gaaacgtaag gattatcaag ggatgttggg ttatctgact gaaaatttac ctcaagtgga
    33541 actcaaaatg accggctttg actatcaagg gtctttggac gagacagatg taacaggtta
    33601 ccatgtaatt ccctcttacc gagaatttat cagcagtttc gaagaaaggg cagacgctca
    33661 agacttgctg ttcgttacag ggtctctcta ttttatctca gaagtacggg gctacctgct
    33721 ggaccgtgag cagataaatt gacccccttg tttgaacttg ttatactagg ggaattgctg
    33781 gttagagaaa atttctctaa attggtagca gaaaggaaat tcatcatgaa attaaaaaga
    33841 ttcacacttt ctcttgcttc tctagcaagt tttagtctct tagtagcttg ttcacaaaga
    33901 gctcaacagg ttcaacagcc tgttgctcag cagcaggtcc aacagcctgc tcaacagaat
    33961 accaatactg caaatgcagg aggtaaccaa aatcaagcgg ctccagtaca aaaccaacct
    34021 gttgctcaac cgaccgatat tgatgggact tatactggtc aggatgacgg agaccgtatc
    34081 actttagtgg taactggaac gactggtaca tggactgagc tcgaatctga cggggatcag
    34141 aaagtcaaac aggttacatt tgattcagca aatcaacgca tgattattgg cgatgatgtc
    34201 aaaatttaca ctgtaaacgg taatcaaatc gtcgtagatg atatggatag agacccatcg
    34261 gaccaaatcg ttttaactaa ataagactat gcaagtagaa agggctggat ttttcagcct
    34321 ttttactttt acctagaaaa taatcataaa tacttgcctt ctaccgaata cctgcgttat
    34381 actagtatca attacttgtt tttagcattc aaactatcaa ggaggggata tgaaatatag
    34441 gaaatttcaa ttattgatgt ccaagtatgg ctttagtctt tcgattatgc tacttgaact
    34501 ttgtcttgtt tttggtctct ttctttattt aggacgcatg gctcccattt tatggattac
    34561 tgtcctcatt ctactgagta tcatcacaat catttcgata gtcaaccgta atacgactcc
    34621 tgagaataag gtaacctggt tgttagtagc ctttgtgcca gtatttggtc ccttgctcta
    34681 tctgatgttt ggtgaaaggc gattgtccaa aaaagaaatc aaacaactga agaagctagg
    34741 ctctatgcat ttccaagaag caaatagcca gctactaaaa gagaaattaa aagaaagtga
    34801 caaggcagct tatggagtca tcaagtcctt attgagtatg gataccaatg ctgacatcta
    34861 tgatcaaact gcctctacat tttttcctaa cggagaagct atgtggaaaa agatggtaga
    34921 agatcttaaa aaggctgaga aatttatttt cttggaatat tacattatag aagaaggttt
    34981 gatgtggaat cgcatactag atatactaga gcaaaaggta gctcagggtg tagaggttaa
    35041 gatgctctat gatgatatcg gctgtatggc tactttaaca ggagattatg cacatcgact
    35101 tcgtcagctg ggcatcgagg cccataaatt caataaagtt attcctcgtt tgacagtggc
    35161 ttataataac agagatcata gaaaaatatt gattgttgat ggtcagatag cctatactgg
    35221 tggggtcaat ctggcagatg agtacattaa ccacgtcgag agatttggtt attggaagga
    35281 tagtggaatt cgcttagacg gactagcagt aaaagctctg acacgcttat ttttgaccac
    35341 ttggtacatt aatcgaggag aaattagtga ttttgatcaa tatcatttag aaaatcattc
    35401 tatcccgagt gacggtttaa ccattccata cggaagtgga cccaagccaa tttttcgagc
    35461 gcaggtaggg aaaaaagttt atcagagttt aatcaatcaa gcaacagaat cggtctatat
    35521 tacgacacct tatttgatta tagattatga tttaacagag acaatcaaaa atgcagctat
    35581 gagaggggtc gatgttcgaa ttatcacccc ttacatacca gataagaagt tcattcagtt
    35641 agtcacgaga ggagcttatc ccgaccttct ttctgctggt gttcggattt atgagtatag
    35701 tccaggtttt attcatagta agcagatgtt ggtagacgaa gattttgcgg tggtggggac
    35761 aatcaatctc gactaccgga gcttggtaca ccattatgaa aatgcagtct tactctataa
    35821 aactccttct ataagggaaa tcgcccgaga ttttcgaaat atatttgcag attctcagga
    35881 agtctatcct cattctatca aaacgagctg gtatcaaaag cttgtaaaag aaatcgccca
    35941 gctattcgcc cctatcttat aagaaatcta gaacttagga tacaaaccag acctattttt
    36001 cttgtctttt acgaatagaa agaaagagga ggggaattca tgctaactaa ggaagaagtg
    36061 aatgatatga ttgagttcaa acagacacat ttacaccgct ttcgggaaat tgaaaccttt
    36121 gtgaaactat gcaaaaaatc actcaaacag ccatcgcaag ctgacaatcc taggactttt
    36181 tgatatacta agacagataa attgaacagg agaaacgata tgagtgtgta tggtagagta
    36241 gaagaagttc ataaggagaa tcgtgaacct ctagaatacc aaatcgaaca agaatcgcat
    36301 catcgtgaat caagtcgtct tcctttggtg aaaattttac tatggagtac gcttgtaacg
    36361 gggataactc taggagtacc gctattactc gacttaatga gtgcacaaga agtgcaggat
    36421 ttttatgcag gttgggcgct tcatcagaca gggaagattt acagcgacta ttatggaagt
    36481 caaggtttgc tttattattt gctgacttac gtgagtcagg gcggattttt ctttgccatc
    36541 tttgagtggt tagccttggt agcaggagga tttttccttt ttagatcagc ggacaccttg
    36601 acagagcaag gagaccaagc tggacatctg gtgactattt tttacatgct agttacaggt
    36661 cttgcttttg gtggaggcta tgcgactctt ttagcgcttc ctttcttatt cgcagccttt
    36721 agtttagttg cggcttacct aagcaatcca agccatgata agggatttgt acggattggg
    36781 ctagctttgg caggcggatt tttctttgct cccttatcat cgctcctgtt tattgctgta
    36841 gtgagtttag gcttgttggt ctttaacctt gggcatagac gctttgcgca tgggttttat
    36901 cagtttcttg cagtggcttt aggtttttca cttgtctttt atccaactgc ctactatagt
    36961 gctgcaacag gaagttttgg ggatgcgatt agtggtattc gttatcctat tgacagtatt
    37021 cgctttgatt ttacttctaa aattttagag aatatgtttt tttatggctt gttgtccctt
    37081 ggtttgggat ttgtggtttg tatcttttta ggtctctttc aatccaaacc ctttaaacta
    37141 tacgtcattt cggttcctgc aagtcttgtg gtaattttag gtttgatttt acttttcttt
    37201 tcacaagagc ctctgcacgc ttcttatttg atggacgtct tccctgtttt cctactttta
    37261 ttggtaacca atattaagag tcaacagagg gggcgtagtg ctagaagaag ccgaagagaa
    37321 acgccagtta gcctatggag tcgtttcttc aaaggaaatc tatatctgct agtttttggg
    37381 tttgtctatc ttttgtctgt tccttttttg atgaagtttg tcctttatcc agtaccttat
    37441 caagaacgta atcgtcttgc tgatttggta aaagaggaga caaatacgga agatgctatc
    37501 tatgcatggg atgatactgc gactctttat cgtaagagtg agcgcttgtc gccatcggcg
    37561 attttgtccc cgttgcacta tacagcaact gaggaaaatc gtaataagtt acttaatgac
    37621 ttgaaagaaa aacaacctaa ggtgattgtg gtaaatgaca aggtggtagt ctggtctgaa
    37681 gtggaaacac tcttaaaaga aaattaccaa caagtaaaga ctgattactc agagtttaaa
    37741 gtctataaaa ttaaataacc aaatcaatat cttgtgtatt tttaaaaatt ttaggatttt
    37801 taacacaaga tattgatttt tctttttaga gtggtataat actttttaga aagaacattt
    37861 tagaaaagag catgcgtatg attgcactag aagaaaaaat tacaattttg ccaactctct
    37921 tcgtcgagaa acgagatggg agacgtgttg tatttgatgt ggacaagatt gacaaggctc
    37981 tccacaaggc ggctgacaag gttatggatg tgacacccct ggttgaaaaa cgcctcaatg
    38041 atctgactga gcgaattatt acagaaattc atagtcgctt tccacaggga attaagattt
    38101 acgaaattca aaatatcgta gaacatgaac tccttgaagc caaagaatat gcactggctg
    38161 aggagtatat tacttatcgg acacagaggg attttgagcg ctcaaaagcg acggatatca
    38221 actttagtat tcataaactt ctcaacaaag accagacagt tgtcaatgaa aatgctaata
    38281 aagacagtga tgtctttaac actcagcgtg atttgacagc agggattgtt gggaaatcaa
    38341 tcggactgca aatgcttcct aagcacgtag ccaatgccca ccaaaagggg gatatccact
    38401 atcacgattt ggactacagt ccctataccc ctatgaccaa ctgctgtttg attgatttta
    38461 agggtatgtt ggaaaatggt tttaagattg gaaatgcaga ggtagagagt cccaagtcta
    38521 tccagactgc gacagcacag atttctcaaa tcattgccaa cgttgcttct agccagtacg
    38581 gtggctgttc agctgaccgt atcgatgaaa ttttggcgcc ttatgcagag aagaactatc
    38641 aaaaacatct caaagatgca gaagagtggg tattgcctga aaaacgggaa gattacgctt
    38701 ggaagaaaac gcaaaaggac atctacgatg ccatgcaatc tcttgagtat gaaatcaata
    38761 ctctcttcac ttcaaatgga caaacacctt ttacttcgct aggttttggt ctgggaacca
    38821 gtcgttttga acgagaaatt caaaaagcta ttttaaacat tcgcatcaag ggtcttggtt
    38881 cagaacaccg tacggctatc tttcctaaac ttattttcac tctgaaaaga ggacttaatt
    38941 tagaggaagg aactcccaac tacgacatca agcagttggc tcttgagtgt gcaaccaaac
    39001 ggatgtatcc agatgtttta tcttacgata agattgttga cttgacagga tccttcaagg
    39061 tgcctatggg ttgccgttct ttcctccaag gatggaaggg tgaaaatggt gtagaagtca
    39121 attcaggtcg catgaatctg ggtgttgtga cggttaatct gcctcgtatc gctcttgagt
    39181 ctgaaggtga tatgaataag ttctgggaaa tcttcaacga gcgaatgaat atcgcagaag
    39241 atgctcttgt ttaccgtgtc gaacgcacta aagaggcgac accagcaaat gctcctattc
    39301 tttatcagta tggtgctttt ggccatcgtc taggtaaaga agaaagtgtt gaccagctct
    39361 ttaagaatcg tcgtgcgacc gtttcgctgg gctatatcgg cttgtatgaa gtagcgacag
    39421 ttttctttgg taacagctgg gaaagtaatc cagatgctaa ggaattcacg ctagacatca
    39481 ttcacgatat gaaacgccgt gtagaagagt ggtcagacca atatggctac catttctcta
    39541 tctactcaac accatccgaa agtctgacag accgtttctg ccgactagat atagacaagt
    39601 ttggctctat tcctgatatc acagacaagg aatactacac caactctttc cactacgatg
    39661 ttcgtaaaaa tccaacaccg tttgaaaaat tggactttga gaaagtctat ccagaagcag
    39721 gtgcgtcagg tggtttcatc cattattgtg agtatccagt ccttcagcaa aatccaaagg
    39781 ccttggaagc tgtctgggat tatgcttatg accgtgtagg ctatctaggc accaatactc
    39841 cgattgaccg ttgctacaag tgtgactttg aaggggattt tgaaccaact gagagagggt
    39901 ttgcttgtcc aaactgtggc aatagcgacc ctaaaacagt agatgtggtg aagcgaactt
    39961 gtggctacct aggtaatcct caagcaagac cgatggtcaa cgggcgtcac aaggaaatcg
    40021 ctgcgcgtgt caaacatatg aatggttcaa cgattaaaat agctgggcat caagtaacaa
    40081 attagaaaga aatgaaatgg gaaaatatca actagacgat aaggggcgcg cacaagtgac
    40141 ccgttatcac gagaaacact ctaaaggtgg agctggtaag aaagaacgct tgcttagctt
    40201 cagagaacaa tttttaaaca agaacaagaa aaaataaaag tgagagccag ctctcgcttt
    40261 tctcatagtg ggaggtaagg atggaattac gcagaccaag attagcggat aagaaagctg
    40321 ttttagatat gatgacagag tttgaaaaat ttcagtcgcc tcacgacggc ggtttatggg
    40381 atacagagaa ctttgtgtat gaagactggt tagaaagcaa tcaggaacag gaaatgggga
    40441 ttaatctgcc tgaaggatgg gttcctgcaa ttcagttagt ggctttttct gagaaaggtc
    40501 aagcagttgg atttcttaat ctccggttgc gcctcagtaa ctttctacta gaagaaggtg
    40561 gccacattgg ctactccatt cgtccatctg aaagaggcaa gggttatgca aaagagactc
    40621 tccgtcaggg cttgcaagtt gctaaggaaa agaacatcaa gaaagctctg gtgacctgta
    40681 gcgtgaataa tcctgctagc agagcagtca ttctagcaaa tggtggaata tttgaggatg
    40741 ctcgcaatgg agtcaagcgt tattggatag aggtagcgaa tgaataatcc aaaaccacaa
    40801 gaatggaaaa gcgaggaact tagtcaaggt cgtatcattg actacaaggc ctttaacttt
    40861 gtggacggcg aaggcgtgcg taactctctc tatgtatcag gctgtatgtt tcactgcgag
    40921 ggatgttata atgtagcgac ctggtccttc aatgcaggca ttccctatac agctgagttg
    40981 gaagaacaga ttatggcaga tcttgcccag ccttatgttc aggggttaac cttactagga
    41041 ggggagcctt ttcttaatac tgggattctc ttgccacttg ttaagcggat tcggaaggaa
    41101 ttgccagaca aggacatctg gtcctggacg ggctacactt gggaagaaat gatgttggaa
    41161 actccagata aactggaact cttgtcactg attgacattc ttgtcgatgg aagatatgat
    41221 cgaactaaga gaaatcttat gctccagttt cgaggttcgt ccaaccaacg aattatcgat
    41281 gtgcaaaaat cgctcaaaag tgggcaagta gtgatttggg acaagctcaa tgacggaaaa
    41341 gaaagctatg aacaggtgaa gagagaatga agaaaaaaga cttagtagac caactagtct
    41401 cagagatcga gacggggaaa gtcaggacac tgggaatata cggtcatgga gcttcaggta
    41461 aatcaacctt tgcacaggaa ttgtaccaag ctttagattc tactacagta aatttgctag
    41521 agacagatcc ttatatcacc tcaggacgcc atctggtagt acccaaggac gcgccgaatc
    41581 aaaaggtgac agccagtctg ccagtggcgc atgaactgga gagtttgcag agagatatcc
    41641 ttgccttgca ggcgagtatg gatgtcttga caattgaaga accttggaag gctagtgagg
    41701 ttttgtctgg agccaaacca attttgattg tcgaagggat gtctgttggc tttctaccca
    41761 aggaactctt tgaaaaaacc atctgtttct acacggatga ggagaccgaa ttaaagcgac
    41821 gccttgctag agatacgact gtgagaaatc gcgatgcatc ctttatattg gctagccatc
    41881 agatgagacg ggagcagtat ctgcgatact ataaagaaac tgagtctaag gcggatatct
    41941 tagtggacca atcagaagat aaatttgatg tcaagaggac ttaacttatg tatagaagaa
    42001 atatagaaga aaatccctaa ttttagaaag aaaaagtagg aaaacagttt catcccaaaa
    42061 aaacgaaaaa acagcaacaa atcccttgca atcgcagggg ctttgtgtta ttctattatg
    42121 gtgctgtaaa ttacagcctt agttttgatg caagaggttg cgacacgctc ggttgcattg
    42181 ccacgcaaca ccgcgtcggt tttcttgtgg agctagccta ttatcttaaa tagacgaaaa
    42241 ggagaaaaag atggcaaaca aaaaaatccg tatccgtttg aaagcttacg aacaccgtac
    42301 gcttgacaca gcggctgcaa aaatcgtaga atcagctact cgtacaggtg cacaagttgc
    42361 gggtccaatc ccacttccaa ctgaacgtag cctctacaca atcattcgtg cgactcacaa
    42421 atacaaagac tctcgcgaac aatttgaaat gcgtacacac aaacgtttga tcgatatcgt
    42481 taacccaact caaaaaacag ttgatgcctt gatgaaattg gatcttccaa gtggtgtaaa
    42541 cgtagaaatc aaactttaat ctaaaatata aaagagcaga ggctggtgtt tcaatctaat
    42601 tgaacacggg ctaaactcgg tgtgaaaaag ataaacttcc tagtgtctgc tagacactgc
    42661 gtcagtttcc tattttgacg ttgagtttga cgtcctttgt atcttagact tgagcataaa
    42721 aaacgctcgt taaaaacttt ttgaataaaa atatagaaaa ggaactattt tctcatgaca
    42781 aaaggaatct tagggaaaaa agtgggaatg actcaaatct tcactgaagc tggcgaattg
    42841 atccctgtaa cagttattga agcaactcca aacgttgttc ttcaagttaa aactgttgaa
    42901 acagacggat acaacgctat ccaagttggt ttcgatgaca aacgcgaagt attgagcaac
    42961 aaacctgcta aaggacatgt agcgaaagct aacacggctc ctaagcgctt cattcgtgaa
    43021 ttcaaaaacg ttgaaggctt ggaagttggc gctgaaatca cagttgaaac attcgcagct
    43081 ggagatgttg ttgacgtaac gggtacttct aaaggtaaag gtttccaagg tgttatcaaa
    43141 cgccacggac aatcacgtgg accaatggct cacggttctc gttaccaccg tcgtccaggt
    43201 tctatggggc ctgttgcacc taaccgcgta ttcaaaggta aaaaccttgc aggacgtatg
    43261 ggtggcgacc gcgtaacaat tcaaaacctt gaagttgtac aagttgttcc agaaaagaac
    43321 gttatcctta tcaaaggtaa cgtaccaggt gctaagaaat ctcttatcac tatcaaatca
    43381 gcagttaaag ctggtaaata ataaagaaag gggaaatcag tcacaatggc aaacgtaaca
    43441 ttatttgacc aaactggtaa agaagctggc caagttgttc ttagcgatgc agtatttggt
    43501 atcgaaccaa atgaatcagt tgtgtttgat gtaatcatca gccaacgcgc aagccttcgt
    43561 caaggaacac acgctgttaa aaaccgctct gcagtatcag gtggtggacg caaaccatgg
    43621 cgtcaaaaag gaactggacg tgctcgtcaa ggttctatcc gctcaccaca atggcgtggt
    43681 ggtggtgttg tcttcggacc aactccacgt tcatacggct acaaacttcc acaaaaagtt
    43741 cgtcgcctag ctcttaaatc agtttactct gaaaaagttg ctgaaaacaa attcgtagct
    43801 gtagacgctc tttcatttac agctccaaaa actgctgaat ttgcaaaagt tcttgcagca
    43861 ttgagcatcg attctaaagt tcttgttatc cttgaagaag gaaatgaatt cgcagctctt
    43921 tcagctcgta accttccaaa cgtgaaagtt gcaactgcta caactgcaag tgttcttgac
    43981 atcgcaaata gcgacaaact tcttgtcaca caagcagcta tctctaaaat cgaggaggtt
    44041 cttgcataat gaatttgtat gatgttatca aaaaacctgt catcactgaa agctcaatgg
    44101 ctcaacttga agcaggaaaa tatgtatttg aagttgacac tcgtgcacac aaacttttga
    44161 tcaagcaagc tgttgaagct gctttcgaag gtgttaaagt tgccaatgtt aacacaatca
    44221 acgtaaaacc aaaagctaaa cgtgttggac gttacactgg ttttactaac aaaactaaaa
    44281 aagctatcat cacacttaca gctgattcaa aagcaatcga gttgtttgct gctgaagctg
    44341 aataatctaa ggaggaaata tcgtgggaat tcgtgtttat aaaccaacaa caaacggtcg
    44401 ccgtaatatg acttctttgg atttcgctga aatcacaaca agcactcctg aaaaatcatt
    44461 gcttgttgca ttgaagagca aggctggtcg taacaacaac ggtcgtatca cagttcgtca
    44521 ccaaggtggt ggacacaaac gtttctaccg tttggttgac ttcaaacgta ataaagacaa
    44581 cgttgaagca gttgttaaaa caatcgagta cgatccaaac cgttctgcaa acatcgctct
    44641 tgtacactac actgacggtg tgaaagcata catcatcgct ccaaaaggtc ttgaagtagg
    44701 tcaacgtatc gtttcaggtc cagaagcaga tatcaaagtc ggaaacgctc ttccacttgc
    44761 taacatccca gttggtactt tgattcacaa catcgagttg aaaccaggtc gtggtggtga
    44821 attggtacgt gctgctggtg catctgctca agtattgggt tctgaaggta aatatgttct
    44881 tgttcgtctt caatcaggtg aagttcgtat gattcttgga acttgccgtg ctacagttgg
    44941 tgttgtcgga aacgaacaac atggacttgt aaaccttggt aaagcaggac gtagccgttg
    45001 gaaaggtatc cgcccaacag ttcgtggttc tgtaatgaac cctaacgatc acccacacgg
    45061 tggtggtgaa ggtaaagcac cagttggtcg taaagcacca tctactccat ggggcaaacc
    45121 tgctcttggt cttaaaactc gtaacaagaa agcgaaatct gacaaactta tcgttcgtcg
    45181 tcgcaacgag aaataatatt aaactagtcg cttaagcaac tagtaaatcc gccagctcgg
    45241 tagcgctcca taggagtgca agccgctgtg gtacaacatt taaaggagaa aatataaaaa
    45301 tgggacgcag tcttaaaaaa ggacctttcg tcgatgagca tttgatgaaa aaagttgaag
    45361 ctcaagctaa cgacgaaaag aaaaaagtta ttaaaacttg gtcacgtcgt tcaacgatct
    45421 tcccaagttt cattggttac actattgcag tttatgacgg acgtaaacac gtacctgttt
    45481 acatccaaga agacatggta ggccacaaac ttggtgaatt tgcaccaact cgtacttaca
    45541 aaggtcacgc tgcagacgac aagaaaacac gtagaaaata aggagaacat aaatggcaga
    45601 aattacttca gctaaagcaa tggctcgtac agtacgtgtt tcacctcgta aatcacgtct
    45661 tgttcttgat aacatccgtg gtaaaagcgt agccgatgca atcgcaatct tgacattcac
    45721 tccaaacaaa gctgctgaaa tcatcttgaa agttttgaac tcagctgtag ctaacgctga
    45781 aaacaacttt ggtttggata aagctaactt ggtagtatct gaagcattcg caaacgaagg
    45841 accaactatg aaacgtttcc gtccacgtgc gaaaggttca gcttcaccaa tcaacaaacg
    45901 tacagctcac atcactgtag ctgttgcaga aaaataagga ggtaaaatcg tgggtcaaaa
    45961 agtacatcca attggtatgc gtgtcggcat catccgtgat tgggatgcca aatggtatgc
    46021 tgaaaaagaa tacgcggatt accttcatga agatcttgca atccgtaaat tcgttcaaaa
    46081 agaacttgct gacgcagcag tttcaactat tgaaatcgaa cgcgcagtaa acaaagttaa
    46141 cgtttcactt cacactgcta aaccaggtat ggttatcggt aaaggtggtg ctaacgttga
    46201 tgcactccgt gcaaaactta acaaattgac tggaaaacaa gtacacatca acatcatcga
    46261 aatcaaacaa cctgatttgg atgctcacct tgtaggtgaa ggaattgctc gtcaattgga
    46321 gcaacgtgtt gctttccgtc gtgcacaaaa acaagcaatc caacgtgcaa tgcgtgctgg
    46381 agctaaagga atcaaaactc aagtatcagg tcgtttgaac ggtgcagata tcgcccgtgc
    46441 tgaaggatac tctgaaggaa ctgttccgct tcacacactt cgtgcagata tcgattacgc
    46501 ttgggaagaa gcagatacta catacggtaa acttggtgtt aaagtatgga tctaccgtgg
    46561 tgaagttctt ccagctcgta aaaacactaa aggaggtaaa taaccaatgt tagtacctaa
    46621 acgtgttaaa caccgtcgtg agttccgtgg aaaaatgcgc ggtgaagcaa aaggtggaaa
    46681 agaagtagca ttcggtgaat acggtcttca agctacaact agccactgga tcactaaccg
    46741 ccaaatcgaa gctgctcgta tcgccatgac tcgttacatg aaacgtggtg gtaaagtttg
    46801 gattaaaatc ttcccacaca aatcatacac tgctaaagct atcggtgtgc gtatgggatc
    46861 tggtaaaggg gcacctgaag gttgggtagc accagttaaa cgtggtaaag tgatgttcga
    46921 aatcgctggt gtatctgaag agattgcacg tgaagcgctt cgacttgcta gccacaaatt
    46981 gccagttaaa tgtaaattcg taaaacgtga agcagaataa ggagaaggca tgaaacttaa
    47041 tgaagtaaaa gaatttgtta aagaacttcg tggtctttct caagaagaac tcgcgaagcg
    47101 cgaaaacgaa ttgaaaaaag aattgtttga acttcgtttc caagctgcta ctggtcaatt
    47161 ggaacaaaca gctcgcttga aagaagttaa aaaacaaatc gctcgtatca aaacagttca
    47221 atctgaagcg aaataataga ctagggaagg agaaatttca atggaacgca ataatcgtaa
    47281 agttcttgtt ggacgtgttg tatctgacaa aatggacaag acaatcacag ttgtagttga
    47341 aacaaaacgt aaccacccag tctatggtaa acgtattaac tactctaaaa aatacaaagc
    47401 tcatgatgaa aacaatgttg ccaaagaagg cgatatcgta cgtatcatgg aaactcgccc
    47461 gctttcagct acaaaacgtt tccgtcttgt agaagttgtt gaagaagcgg tcatcatcta
    47521 atcaaacctg aaaggagaaa actgaaatga ttcaaacaga aactcgtttg aaagtcgcag
    47581 acaacagcgg tgctcgcgaa atcttgacta tcaaagttct tggtggttca ggacgtaaat
    47641 ttgcaaacat cggtgatgtt atcgtggcat ctgtaaaaca agctactcct ggtggtgcgg
    47701 ttaaaaaagg tgacgttgtt aaagcagtta tcgttcgtac taaatcaggt gctcgtcgtg
    47761 ctgatggttc atacatcaaa tttgacgaaa acgcagcagt tatcatccgt gaagacaaaa
    47821 ctcctcgcgg aacacgtatc tttggcccag ttgcacgtga attgcgtgaa ggtggtttca
    47881 tgaagatcgt gtcacttgct ccagaagtac tttaattttt aggaacaaac tagtccccta
    47941 gcttcaagct agggtgccct tatgggcgta agaaaaatca aggagaaacc taatgtttgt
    48001 aaaaaaaggc gacaaagttc gcgtaatcgc tggtaaagat aagggaacag aagctgttgt
    48061 ccttactgcc cttccaaaag taaacaaagt tatcgttgaa ggtgttaaca ttgttaagaa
    48121 acaccaacgt ccaactaacg agcttcctca aggtggtatc atcgagaaag aagcagctat
    48181 ccacgtatca aatgttcaag ttttggacaa aaatggtgta gctggtcgtg ttggttacaa
    48241 atttgtagac ggtaaaaaag ttcgctacaa caaaaaatca ggcgaagtgc ttgattaatc
    48301 acgaaggaaa ggagaagtat aatggcaaat cgtttaaaag aaaaatatct taatgaagta
    48361 gttcctgctt tgacagaaca attcaactac tcatcagtga tggctgtgcc taaagtagat
    48421 aagattgttt tgaacatggg tgttggtgaa gctgtatcaa acgctaaaag ccttgaaaaa
    48481 gctgctgaag aattggcact tatctcaggt caaaaaccac ttatcactaa agctaaaaaa
    48541 tcaatcgccg gcttccgtct tcgtgaaggt gttgcgatcg gtgcaaaagt tacccttcgt
    48601 ggtgaacgta tgtacgaatt cttggataaa ttggtatcag tttcacttcc acgtgtacgt
    48661 gacttccacg gtgtcccaac aaaatcattt gatggacgcg ggaactacac acttggtgtg
    48721 aaagaacaat taatcttccc agaaatcaac ttcgatgacg ttgacaaaac tcgtggtctt
    48781 gacatcgtta tcgtaacaac tgctaacact gacgaagagt cacgtgcatt gcttacaggc
    48841 cttggaatgc cttttgcaaa ataatatagg aggtaaatct aatggctaaa aaatcaatgg
    48901 tagctagaga ggctaaacgc caaaaaattg ttgaccgtta tgctgaaaaa cgtgctgcat
    48961 taaaggcggc aggggactac gaaggtttat ctaaattacc tcgcaacgcc tcaccgactc
    49021 gtttacataa tcgttgtagg gttacggggc gcccacattc agtttaccgc aaatttggtc
    49081 tgagtcgtat cgcttttcgc gaacttgcgc ataaaggtca aattcctggt gtaacaaaag
    49141 catcttggta atttaagata tcaagagcgt caaaactcca agtaaaaata ggaaacttga
    49201 cgaagaaact aaagtttcta ggaaagttta tctttttcac acagagttta gcccgtgttc
    49261 aattgggctt gccaatttga acacgagcta cagctttggc aaaaaagacc aatttgcttt
    49321 ggagcattgc ttctgcatta aattgtctat ttttgctcgt gctgttacgc tctttgtatc
    49381 atgtattaac tagcaagtgc aacttgcaaa ctactagtaa gaggagaaaa acaaaatggt
    49441 tatgactgac ccaatcgcag acttcctaac tcgtattcgt aatgctaacc aagctaaaca
    49501 cgaagtactt gaagtacctg catcaaacat caaaaaaggg attgctgaaa tccttaaacg
    49561 cgaaggtttt gtaaaaaacg ttgaaatcat tgaagatgac aaacaaggcg tcatccgtgt
    49621 atttcttaaa tacggaccaa atggtgagaa agttatcact aacttgaaac gtgtttctaa
    49681 accaggactt cgtgtctaca aaaaacgtga agaccttcca aaagttctta acggacttgg
    49741 aattgccatc ctttcaactt ctgaaggttt gcttactgat aaagaagcac gccaaaagaa
    49801 tgttggtggt gaggttatcg cttacgtttg gtaaaatcaa gatacaaagc tcgtaaagaa
    49861 caaagcaaaa ttaggaagtt ggagaagttt gtttacaaac aagccaactt atctattttg
    49921 cacagttctt agagcgtgtt cagttcagct cttgaactaa ataagtatct gaaccccgtg
    49981 aaaactggcc gttctggcct gacaatctaa caggagaaaa taaacatgtc acgtattggt
    50041 aataaagtta tcgtgttgcc tgctggtgtt gaactcgcta acaatgacaa cgttgtaact
    50101 gtaaaaggac ctaaaggaga acttactcgt gagttctcaa aagatattga aatccgtgtg
    50161 gaaggtactg aaataactct tcaccgtcca aacgattcaa aagaaatgaa aactatccac
    50221 ggaactactc gtgccctttt gaacaacatg gttgttggtg tatcagaagg attcaagaaa
    50281 gaacttgaaa tgcgtggggt tggttaccgt gcacagcttc aaggatctaa acttgttttg
    50341 gctgttggta aatctcatcc agacgaagtt gaagctccag aaggaattac ttttgaactt
    50401 ccaaacccaa caacaatcgt tgttagcgga atttcaaaag aagtagttgg tcaaacagct
    50461 gcttacgtac gtagccttcg ttcaccagaa ccatataaag gtaaaggtat ccgttacgtt
    50521 ggtgaattcg ttcgccgtaa agaaggtaaa acaggtaaat aatgttgagt ggttgatcat
    50581 caaccaccaa cctattttcc aactttgtgc atagcacacg atttaaaact aaagaggtga
    50641 aaactgtgat ttcaaaacca gataaaaaca aactccgcca aaaacgccac cgtcgcgttc
    50701 gcggaaaact ctctggaact gctgatcgcc cacgtttgaa cgtattccgt tctaatacag
    50761 gcatctacgc tcaagtgatt gatgacgtag cgggtgtaac gctcgcaagt gcttcaactc
    50821 ttgataaaga agtttcaaaa ggaactaaaa ctgaacaagc cgttgctgtc ggtaaactcg
    50881 ttgcagaacg tgcaaacgct aaaggtattt cagaagtggt gttcgaccgc ggtggatatc
    50941 tatatcacgg acgtgtgaaa gctttggctg atgcagctcg tgaaaacgga ttgaaattct
    51001 aataggagga cactagaaaa tggcatttaa agacaatgca gttgaattag aagaacgcgt
    51061 agttgctgtc aaccgtgtta caaaagttgt taaaggtgga cgtcgtcttc gtttcgcagc
    51121 tcttgttgtt gttggtgacc acaatggtcg cgtaggattt ggtactggta aagctcaaga
    51181 agttccagaa gcaatccgta aagcagtaga tgatgctaag aaaaacttga tcgaagttcc
    51241 tatggttgga acaacaatcc cacacgaagt tctttcagaa ttcggtggag ctaaagtatt
    51301 gttgaaacct gctgtagaag gttctggagt tgccgctggt ggtgcagttc gtgccgttgt
    51361 ggaattggca ggtgtggcag atattacatc taaatcactt ggttctaaca ctccaatcaa
    51421 cattgttcgt gcaactgttg aaggtttgaa acaattgaaa cgcgctgaag aaattgctgc
    51481 ccttcgtggt atttcagttt ctgatttggc ataagaaagg ggataaaatg gctcaaatta
    51541 aaattacttt gactaagtct ccaatcggac gcattccatc acaacgtaaa actgttgtag
    51601 cacttggact tggcaaattg aacagctctg ttattaaaga agataacgct gctatccgtg
    51661 gtatgatcac agcagtatct cacttagtaa cagttgaaga agtaaactaa tgaagtttta
    51721 ggggatgtgc actgtaccat cccctaaaac tagatatagt catctatgat gacatcgtat
    51781 aggcgagttg atgggggaga caaccttttc tcccttatcg gcgctagcat tttacaaaag
    51841 aggagaaaat aaaaatgaaa cttcatgaat tgaaacctgc agaaggttct cgtaaagtac
    51901 gtaaccgcgt tggtcgtggt acttcatcag gtaacggtaa aacatctggt cgtggtcaaa
    51961 aaggtcaaaa agctcgtagc ggtggcggag ttcgccttgg ttttgaaggt ggacaaactc
    52021 cattgttccg tcgtcttcca aaacgtggat tcactaacat caacgctaaa gaatacgcaa
    52081 ttgtgaacct tgaccaattg aacgtctttg aagatggtgc tgaagtaact ccagttgttc
    52141 ttatcgaagc aggaattgtt aaagctgaaa agtcaggtat taaaattctt ggtaacggtg
    52201 agttgactaa gaaattgact gtgaaagcag ctaaattctc taaatcagct gaagaagcta
    52261 tcactgctaa aggtggttca gtagaagtca tctaagagag gtgacctatg ttttttaaat
    52321 tattaagaga agctcttaaa gtcaagcagg ttcgatcaaa aattttattt acaattttta
    52381 tcgttttggt ctttcgtatc ggaactagca ttacagttcc tggtgtgaat gccaatagct
    52441 tgaatgcttt aagtggatta tccttcttaa acatgttgag cttggtgtcg gggaatgccc
    52501 taaaaaactt ttcgattttt gccctaggag ttagtcccta tatcaccgct tctattgttg
    52561 tccaactctt gcaaatggat attttaccca agtttgtaga gtggggtaaa caaggggaag
    52621 taggtcgaag aaaattgaat caagctactc gttatattgc tctagttctc gcttttgtgc
    52681 aatctatcgg gattacagct ggttttaata ccttggctgg agctcaattg attaaaactg
    52741 ctttaactcc acaagttttt ctgacgattg gtatcatctt aacagctggt agtatgattg
    52801 tcacttggtt gggtgagcaa attacagata agggatacgg aaacggtgtt tccatgatta
    52861 tctttgccgg gattgtttcc tcaattccag agatgattca gggcatctat gtggactact
    52921 ttgtgaacgt cccaagtagc cgtatcactt catctatcat tttcgtaatc attttgatta
    52981 ttactgtatt gttgattatt tactttacaa cttatgttca acaagcagaa tacaaaattc
    53041 caatccaata tactaaggtt gcacaaggtg ctccatctag ctcttacctt ccgttaaagg
    53101 taaatcctgc tggagttatc cctgttatct ttgccagttc gattactgca gcgcctgcgg
    53161 ctattcttca gtttttgagt gccacaggtc atgattgggc ttgggtaagg gtagcacaag
    53221 agatgttggc aactacttct ccaactggta ttgccatgta tgctttgttg attattctct
    53281 ttacattctt ctatacgttt gtacagatta atcctgaaaa agcagcagag agcctacaaa
    53341 agagtggtgc ctatatccat ggagttcgtc ctggtaaagg tacagaagaa tatatgtcta
    53401 aacttcttcg tcgtcttgca actgttggtt ccctcttcct tggtgtgatt tccattttac
    53461 cgattgcagc taaagatgta tttggtcttt ctgatgttgt tgcctttggt ggaacaagtc
    53521 tcttgatcat tatctctaca ggtatcgaag gaatcaagca attggaaggt tacctattga
    53581 aacgtaagta tgttggtttc atggacagaa cagaataaaa gtatttactg aatcagtaaa
    53641 tgctgaggga gtggaggttt aaactctgac atttgtaaga gttggatctc ccctcttcta
    53701 ttttgttttt aaataggggt gaaaagactt tttgcttcta tttaaaaata aaataaggag
    53761 atcaaatcat gaatcttttg attatgggct tacctggtgc aggtaaggga actcaagcag
    53821 caaaaatcgt agaacaattc catgttgcac atatctcaac aggtgatatg ttccgcgctg
    53881 caatggcaaa tcaaactgaa atgggtgttc ttgctaagtc atatattgac aagggtgaat
    53941 tggttcctga cgaagttaca aatggaatcg taaaagaacg tctttcacaa gatgatatta
    54001 aagaaacagg attcttattg gatggttacc cacgtacaat tgaacaagct catgccttgg
    54061 acaaaacatt ggctgaactt ggcattgaac tagaaggtgt tatcaatatt gaagtgaacc
    54121 ctgacagcct cttggaacgt ttgagtggcc gtatcatcca ccgcgtaact ggagaaactt
    54181 tccacaaggt ctttaaccca ccagttgact ataaagaaga agattattac caacgtgaag
    54241 atgataagcc tgagacagta aaacgtcgtt tggatgttaa tattgctcaa ggagaaccaa
    54301 tcattgctca ctaccgtgcc aaaggtttgg ttcatgacat cgaaggtaat caagatatca
    54361 atgatgtctt ctcagatatt gaaaaagtat tgacaaattt gaaataaagc gtttttcata
    54421 cttgcaaaaa ttcgctacaa atgttatact gaaatagtct gacttataat tgttgtctct
    54481 gtgtctagag gcatcgaatc gaaatttatg gaggtgcttt tgcgtggcaa aagacgatgt
    54541 gattgaagtt gaaggcaaag tagttgatac aatgccgaat gcaatgttta cggttgaact
    54601 tgaaaatgga catcagattt tagcaacagt ttctggtaaa attcgtaaaa actatattcg
    54661 tattttagcg ggagatcgtg ttactgtcga aatgagtcca tatgacttga cacgtggacg
    54721 tatcacttac cgctttaaat aatcgaaaaa cttggaggga taagaaatga aagtaagacc
    54781 atcggtcaaa ccaatttgcg aatactgtaa agttattcgt cgtaatggtc gtgttatggt
    54841 aatttgccca gcaaatccaa aacacaaaca acgtcaagga taagatagaa aggagaaaac
    54901 atggctcgta ttgctggagt tgatattcca aatgacaaac gcgtagtaat ctcattgact
    54961 tatgtttatg gtatcggact tgcaacatct aagaaaattt tggctgctgc tggaatctca
    55021 gaagatgttc gtgtacgtga tcttacatca gatcaagaag atgctatccg tcgtgaagtg
    55081 gatgcaatca aagttgaagg tgaccttcgt cgtgaagtaa acttgaacat caaacgtttg
    55141 atggaaatcg gttcataccg tggtatccgt caccgtcgtg gacttcctgt ccgtggacaa
    55201 aatactaaaa acaacgctcg cactcgtaaa ggtaaagctg ttgcgattgc tggtaagaaa
    55261 aaataatata ggaggtaaaa gtcttggcta aaccaacacg taaacgtcgt gtgaaaaaga
    55321 atatcgaatc tggtattgct catattcacg ctacatttaa taacactatt gttatgatta
    55381 ctgatgtgca tggtaatgca attgcttggt catcagctgg tgctcttggt ttcaaaggtt
    55441 ctcgtaaatc tacaccattc gctgctcaaa tggcttctga agctgctgct aaatctgcac
    55501 aagaacacgg tcttaaatca gttgaagtta ctgtaaaagg tccaggttct ggtcgtgagt
    55561 cagctattcg tgcgcttgct gccgctggtc ttgaagtaac agcaattcgt gatgtgactc
    55621 cagtgccaca caatggtgct cgtcctccaa aacgtcgccg tgtataatca tcgcattaca
    55681 ctgcttttcg tttaagaggg agtaactaaa tgatcgagtt tgaaaaacca aatataacaa
    55741 aaattgatga aaataaagat tatggcaagt ttgtaatcga accacttgaa cgtggctacg
    55801 gtacaactct tggtaactct cttcgtcgtg tacttctagc ttctctacca ggagcagctg
    55861 tgacatctat caacattgat ggtgtgttac atgagtttga cacagttcca ggtgttcgtg
    55921 aagacgtgat gcaaatcatt ctgaacatta aaggaattgc agtgaaatcg tacgttgaag
    55981 acgaaaaaat catcgaactg gatgttgaag gtcctgctga agtaacagct ggtgacattt
    56041 tgacagatag cgatattgaa attgtaaatc cagatcatta tctctttaca attggtgaag
    56101 gttcttctct aaaagcgact atgactgtta acagtggtcg tggatatgta cctgctgatg
    56161 aaaataaaaa ggataatgca ccagttggaa cacttgctgt agattctatt tatacaccag
    56221 ttacaaaagt caactatcaa gtggaacctg ctcgtgtagg tagcaatgat ggtttcgaca
    56281 aattaaccct tgaaatcttg acaaatggaa caattattcc agaagatgct ttagggcttt
    56341 cagcacgtat tttgacagaa catcttgatt tgtttacaaa tcttactgag attgctaagt
    56401 caactgaagt gatgaaagaa gctgatactg aatctgacga ccgtatttta gatcgtacga
    56461 ttgaggaact ggacttgtct gtgcgttcat acaactgttt aaaacgtgcc ggtatcaata
    56521 ctgtgcatga tttgacagaa aaatctgaag cagagatgat gaaagtacga aatcttggac
    56581 gcaagagttt ggaagaagtg aaactcaaac tcattgattt gggtcttgga ttaaaagata
    56641 aataaaggag gaatacatgg cttaccgtaa actaggacgc actagctcac aacgtaaagc
    56701 aatgcttcgc gatttgacaa ctgacctttt gatcaacgaa tcaatcgtga caactgaagc
    56761 tcgtgctaaa gaaatccgta aaactgttga aaaaatgatt actctaggta aacgtggtga
    56821 tttgcatgca cgtcgtcaag cagctgcttt cgtacgtaat gaaatcgcat ctgaaaacta
    56881 tgatgaagca actgataagt acacttctac tacagcactt caaaaattgt tctcagaaat
    56941 cgcacctcgt tatgctgaac gtaacggtgg atacactcgt atccttaaaa ctgaaccacg
    57001 tcgtggtgat gcagcgccaa tggcgatcat cgaattagta taaaatcatc aattttgttg
    57061 agtgttatga tgatggagtc ttgtgctctt agtctagctc tggtctaccg ctaggatttc
    57121 ggtcctagcg ggaacactca tcataagttg ggatagtaga cgcttgttta cgaaattgtt
    57181 tttttcttaa gaacaacttc gtaagcaggc gtttttgagt attttcgtta gaattatgct
    57241 atactatttg aaaagaatcc tgtttaatgt taaggtttct tattttaaga agaattggag
    57301 tttacttatg aaagccatta taactgttgt tggtaaagat aaatctggaa ttgttgcagg
    57361 tgtttctggt aaaattgcag aattaggatt gaatattgac gatatctctc aaactgtctt
    57421 ggatgaatat tttacgatga tggctgttgt atctagtgat gaaaagcaag attttaccta
    57481 tcttcgtaat gaatttgaag cttttgggca aactttgaat gtaaaaatca atattcagag
    57541 tgcagcgatt ttcgaagcta tgtataatat ctaggaggtc atcatggata ttagacaagt
    57601 tactgaaacc atcgccatga ttgaggagca aaacttcgat attagaacca ttaccatggg
    57661 gatttctctt ttggactgta tcgatccaga tatcaatcgt gctgcggaga aaatctatca
    57721 aaaaattacg acaaaggcgg ctaatttagt agctgttggt gatgaaattg cggctgagtt
    57781 gggaattcct atcgttaata agcgtgtatc ggtgacacct atttctctga ttggggcagc
    57841 gacagatgcg acggactacg tggttctggc aaaagcgctt gataaggctg cgaaagagat
    57901 tggtgtggac tttattggtg gtttttctgc cttagtacaa aaaggttatc aaaagggaga
    57961 tgagattctc atcaattcca ttcctcgcgc tttgactgag acggataagg tctgctcgtc
    58021 agtcaatatc ggctcaacca agtctggtat taatatgacg gctgtggcag atatgggacg
    58081 aattatcaag gaaacggcaa atctttcaga tatgggagcg gctaagttgg ttgtattcgc
    58141 taatgctgtt gaggacaatc catttatggc gggtgccttt catggtgttg gggaagcaga
    58201 tgttatcatc aatgtcggag tttctggtcc tggtgtggtg aaacgtgctt tggaaaaagt
    58261 tcgtggacag agctttgatg tagtagccga aacagttaag aaaactgcct ttaaaatcac
    58321 tcgtatcggt caattggttg gtcaaatggc cagtgagaga ctgggtgtgg agtttggtat
    58381 tgtggacttg agtttggcac caacccctgc gattggagac tctgtggcac gtgtccttga
    58441 ggaaatgggg ctagaaacag ttggcacgca tggaacgacg gttgccttgg ccctcttgaa
    58501 cgaccaagtt aaaaagggtg gagtgatggc ctgcaaccaa gtcggtggtt tatctggcgc
    58561 ctttatccct gtttctgagg atgaaggaat gattgctgca gtgcaaaatg gctctcttaa
    58621 tttagaaaaa ctagaagcta tgacggctat ctgttctgtt ggattggata tgattgccat
    58681 cccagaagat acgcctgctg aaaccattgc ggctatgatt gcggatgaag cagcaatcgg
    58741 tgttatcaac atgaaaacaa cagctgttcg tatcattccc aaaggaagag aaggcgatat
    58801 gattgagttt ggtggtctat taggaactgc acctgttatg aaggttaatg gggcttcgtc
    58861 tgtcgacttc atctctcgcg gtggacaaat cccagcacca attcatagtt ttaaaaatta
    58921 agaaaatagg agaaatttta agttctattt aagattagat gtgtatacta taatcattaa
    58981 ataaagacct cctaatatta tttgaaacag ataacactga attagtttga atttgatttt
    59041 catctaatat ctttatttaa tgaactccta aactttttca taataatctc cttcaaaagt
    59101 cgcctgtatg ggtggctttt attttatcat tcatgatata atagaagcaa acggaggacg
    59161 gaaaatggta aaagtacgat tgtatttggt acgtcatggc aagaccatgt ttaacacgat
    59221 tggtcgcgcg caaggttgga gcgatactcc cttaactgct gaaggtgaac gagggattca
    59281 agagttagga atcggtttgc gagaatctga tctacagttt gagcgcgctt attcgagtga
    59341 ttctggtcgt accattcaga ccatgggaat tatccttgaa gaacttggct tgcaggggaa
    59401 aatcccttat cgcatggaca agcgtatcag agaatggtgt ttcggtagtt ttgatggagc
    59461 ctatgatggc gatcttttca tgggcattat tcctcgtatc tttaatgtgg accacgttca
    59521 ccaattgtct tatgctgaac tggctgaggg cttggtagag gtcgatacag ctggttgggc
    59581 tgaaggctgg gaaaaactca gtggccgaat caaggaaggc tttgaaatga ttgcaaaaga
    59641 aatggaagat caaggtggag gtaacgccct tgttgtcagc catggaatga ctattggaac
    59701 cattgtttat ctgattaatg gcatgcatcc gcatggtcta gataatggta gcgtgacgat
    59761 tcttgaatat gaggacggtc agtttagggt tgaagttgtc ggtgaccgta gttaccgaga
    59821 gctaggatgt gagaagatgg aagaaggctc tatttaatca gtctagactt gcttgccatg
    59881 agctagggat ttgataagaa tatcaagata agaaaaaaca gccgagggca ctcctttcgg
    59941 ctgtttttga tgtggaaaac taaagtgtaa tgctattgct tttagagatt ttcataaaca
    60001 agagcaagga acctactgtt agaacagtca ggatagttga caaggctgcg gctacaccgt
    60061 aatttcctct gagaacctct gtataaatag ctacagtcat tgttcttgtt ttgacattgt
    60121 agaggaggat agaagtagag agttttgaaa tcattgtgac ccaagataag atggctccag
    60181 aaatgatacc agatagcatc attggagttg taatcttagc aaaggtattg agacgactac
    60241 ttcctaagct ttcagcagct tcttcaatac ttggtgctat ttgttgtaag ctagcaacag
    60301 atgagcgaat agtataaggt aatcttctga cagatagaga cataatcaag atgaaagcag
    60361 tccctgtaat cataagaaat ccacttccaa atagaccagt attgaaggaa gaaatgaagg
    60421 caatccctag aacggttcct ggtacaatat aaggtaccat actgaggctg tcaattaagt
    60481 ttgtaaacaa attccgtttt ctaacggcta ggtaggagat aaatgtcgca aatagaacaa
    60541 ctagaactaa ggcaatcaaa gggatacgaa tggtattgaa aatagcagat cccatacgat
    60601 tgaaagctac cttgtaactg tttggagaat aacctttaac agataccata cctgatgttt
    60661 ttaggaaaga ggtataaatt aagtagattt gaggtaaaac agagataaag ataattccgt
    60721 agactgttgc ataaatggca gctatttttc cttttgtagt ttttttaggc tcaattggat
    60781 ggagcagatt catgctgaaa ctgtagcggt ttgcaatgtg tttttggata aggaaaattg
    60841 ccaaggcaat gataatcgcc ataattgcaa aagcagaatt tcctccaacc tcgctaataa
    60901 attgggtata aatcaggaca gggaaagtcc gatatccttc gtcaatcaac ataggcgttc
    60961 caaagtctga gaatgctctc ataaatacaa gcaaggagct gctagtaagg ttggaactag
    61021 gagaggtaaa acaaccgtta cgatacgctt aaatccgaag gaccccatgc tttcagctgc
    61081 ttcaagtaga gaattgtcaa tactgttcat tgttccagca acatatagaa ataccagtgg
    61141 gaatagttgc agtgtaaaga caagtacaat tcctttgaat ccataaatat cgatagctgg
    61201 aagatgaagg gcatttgtca aaaatttagt gatgacctca tttcgtccca gcaagagaat
    61261 tcaggagtag gctcctacga aaggagctga catggaagca atgataatca atatttgtag
    61321 aaatttcttc cccttgaagt catacataga gaagagataa gctaataggg ttcctacaac
    61381 taaggaagtg atagtagcgg taatggaaac cttgaaactg ttgactagtg tctcagagta
    61441 gtaggcttta ctaaagaaag tgacaaaatt agctagtgag aattgtcctt catgtataag
    61501 tgcttgcttg agcacggtaa cgataggata aacgagaaag acaagatagg taagaaagat
    61561 gaagaaagag gaagctgtcc aaatatttag ttttttacat tccatggttg actcctttta
    61621 tcaggttttg ggaaccatct gcagaaaaga tgtttaattt ttgcgtattg attcgtagac
    61681 gaatacgatt gcctttttgt agttcttctt caaaagttga ttcttcacta acttaaattt
    61741 ttgaggcaaa acctgtctca atgaaatact ccgtatttag tccaagatag acgctatcgc
    61801 taatagttcc ttcgatatct ccagattcat ctttgataaa ctcttcggga cgaatgctta
    61861 catgaatagc ttgctcctca acctgatcaa gagctggcat tcgaagggca tagccatctg
    61921 aaaagacgat ataagcgccg tcgctccgtt tttcaagatt ggcagggata atatttgtgc
    61981 gtccgataaa ggttgccaca aactcattag ctggtttatg atagagttat tttggtcggc
    62041 cgatttgttg gatcacccca tctttcataa cagcaatttg gtctgaaata gccatggctt
    62101 cttcttggtc gtgggttaca taaacagttg taattcccac ttcgtgttgg atttctcgga
    62161 tggcttgacg catatccaag cgaagtttgg cctccagatt actaagtggc tcgtccatga
    62221 ggagaacact tggattaacc gctaaggcgc atgccaaggt gacacgttgt tgttgtccac
    62281 cactgagttt atcgggcttt cgatccgcat attgagcaat ttgcatgagt tcaagatact
    62341 tgttggtctg ttgaatcaat tcttcttttg gaaccttctt ttgcataaga ccaaaagcaa
    62401 cgttgtctcg gacagtcaaa tgtgggaaaa tagcgtagtt ttggaaaacc atcccgatat
    62461 tgcgtttgct gggttccata ttattgattt ttgtatcatc gaagtaaaat tctccacctt
    62521 cgatactgtt gaaacctgca atcatacgaa gaagggtcgt tttcccacat cctgaagctc
    62581 caagaagggt aaagagactt ccttttggaa ttgtaatgtt caaattctca ataacaggga
    62641 catcgtggta gatttttttg gcgttaataa tttcgatctc actcatagtg aacctctttt
    62701 actgtttaga ttggatatct gtaaagactt cgttgtattt cttaacgata tctgatttat
    62761 tcttgatgac ataatcataa tcttcagtga gtgttttgat tttgtcaatt ggtttcatgt
    62821 tttcgcttgt tttagcattt ttacgaacag gacggttagt agtggttgta ccaagtgtat
    62881 cttgtacttc ttgagagata ataaaatcga taaatttctt ggcattttcc atatttttag
    62941 attttttaac gatagcagca ctagcaggta ggaagacggt tccttctttt ggatagacta
    63001 ccttaatgtt agctccgtca tttaagagtt taactgctgg atcttcataa gagagactaa
    63061 cagtcatttc tccatcagcg actgctttat agacaccaga tgaacttaaa ccgattttat
    63121 agtatattga aactagaata gtacacatct acttctaaaa cattgttaga aatcgatttg
    63181 actgtcctga ttaatttgtc ctgttcttat ttcattttac tataccatca ataagtgtga
    63241 aaagatcttt tacataagac caagccttat catctttgta accaccttga gcttgtagca
    63301 tatttgttaa ttgagcaaag gcgctagaag agtttgctgg gtcagcagtt gcgatttttc
    63361 cttttagttc aggtttgaga aggtcgctat atccttcgat gttcatgcct ttagttaaat
    63421 cagggtggac gattaaaaca ctaccatcta gtgtataagg agtagagaag ccagttgtgt
    63481 tttgatattc tttgataaca ttatcatttt cttttgaaat atagttttca aagagttctc
    63541 cgtgggtagc atattgtgta taagaaccac caaagataat atcagctaca ggaacttctt
    63601 tttctgactc tagttttttg aaaagttctc cagtaccagc ttgaatcagt tctattttga
    63661 taccatattt ttcttcaaag gcaggaatag ttgctccaat taagccttct gagtttggtg
    63721 aataaacgac tagcgaacca ccgtctcctt tatcagatga actgtcatcg gcagattcat
    63781 tagaagaaca agcagcataa tacatccatt tctttttcat gatggatacc tccgttgtgt
    63841 tatttaagtt tattttaaaa caatgtaagc gtttttaaaa cctacaattc tattctatag
    63901 tgtattgaat ctataacagt acacattgac tgctaaaata tttctataaa ttaatttgac
    63961 tttcctgata gagatgttca catcttattt caattcacta tattagagta aaattctcta
    64021 caaaaaaaag aatagcctat tttactattt ttccgagtga tttcaattcc tttggggaaa
    64081 tatggagata ctttttaaat cctgacaaat ggttgtttct ttttctaaat cggtgatact
    64141 gtatcggaga atgcgcgtga ggtcacaaag gctgcgatag agcttctatg gagaatttct
    64201 ttttggagag attttttaaa ggaatgagac atccgctacc tccttggaag gtttttttgt
    64261 gataagtata gcagtttaaa aattctagag caaggtaaaa tagaaaaggt ttggctaaaa
    64321 ttttttagct aaaccttttg aaaagttaag tatgtattat agatgcttgt tatctgcaaa
    64381 tagctagagc atttcaagga aataaactag aaataacaat taatatggtg gttcagaaat
    64441 accttttgat aatcaataag atcttcagga tgaagtgcgt tgattccatc catttcatat
    64501 ttccgattta ataaacgata tttgttttca ccaaattgat gaaaagggag tagttgaact
    64561 tggtcgatat ttaatgagtt aaatagagta gcgaattttt ctgcatcctc taaactattg
    64621 ttaaaattag gaataactgg gattcttaaa acgatagttt tattttgtga aaaagcataa
    64681 tgaatgtttt taataatcat ttgattaaaa accccagtca cttttttatg ttttatagaa
    64741 ttataatgtt ttaggtctgt gtagataaaa tccacatatt gaattaaatc aataaatttt
    64801 tcatgatcaa caaaggcagt agtttcaatg gcagtgtgta tgtgatgttc tttagctgat
    64861 tttaagatag ctttagcaaa ttcaaactga gcaaatattt cacctcctga taaagttaaa
    64921 cctccaccgg attcttcgta aaattctttg tcttttaata cctctgtaat aatttcttct
    64981 acagtctttt cttcaccgac taaggtgaat ttctctcgtt gagcatcttt cattttttca
    65041 ggtttcattc tttgagattc aggattagaa caccatggac agcgcagagg acatcctttt
    65101 aaaaaaacag ttgtacgaat acccgggccg tcatgaattg aaaagtgttg aatattaaaa
    65161 ataattcctt tagatatttc cataagagtt cctcctcttc ataagtctat cctatcacaa
    65221 aaacgaaaga aaaacaatta cgaacgaaag gttaatttgt tgttttttgc tttttatttt
    65281 ggtagaataa aacggaggtg taaaatgaaa agattggaac aaattattaa attagtatca
    65341 gaatatgaaa agatcgacgt taatacatta tcggaaaaat taaatgtatc gaaagtaacg
    65401 attagaaaag atttagataa attagagtca aaaggtttat tacacagaga gcatggatat
    65461 gctgtattaa atagtggaga tgacttaaat gtacgtttgt caattaatta tgaaattaag
    65521 agaaaaattg ttcaggaagc agtaaaattg gtgtcagata atgaaacgat aatgatagaa
    65581 tctggatcga cctgtgcttt acttgctgag gaaatttgca agcaaaaaag aaatgttacg
    65641 attgtaacaa attcattttt tatagcaaat tttgtgagag cttatgattc atgtcgtatt
    65701 attgttcttg gtggagagtt tcagaaggat tcacaggtta ctgtgggacc tttattaaaa
    65761 gaaatgatac agacttttca tgtgcatcaa gcttttgttg ggacagatgg atacgataaa
    65821 gagatgggct ttacaggaaa agatttaatg cgcagtgagg tagttcaata tatttcagca
    65881 gcgtcggata aagtcattgt cctaactgac tcaagtaaat ttgataaaag gggtacagta
    65941 agaagatttg ctttaagtca agtctatgaa gtaataacag acgaaaaact ttctaaacaa
    66001 aatatagcta cattagaaaa tgctgggata atggttaagg tagtttcgta agaggttaag
    66061 tgtatgaatc aagataggaa taaactgctc tctaaaattg cttatctgta ttatattgaa
    66121 aacttaaatc agtcacaaat agcagcaaaa ttaggaattt atagaacctc tattagtaga
    66181 atgttaacag aagcaaggaa tgcaggaatt gttaaaattg aaatagagaa ttttgatacc
    66241 aatatgttta agttggaaaa ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt
    66301 attccaaatg aatttgatga taatccaaca attttatctg aaagaatttc tcaagttgca
    66361 gcaggtgtcc ttaggaatct aattgatgat aatatgaaaa ttggcttttc ttgggggaaa
    66421 agtttaagta atttagtaga tttaattcac agtaaaagtg tccgaaatgt tcacttctat
    66481 cctctagcag gtggtcctag tcacatacac gctaaatacc atgtgaatac actgatttat
    66541 gaaatgtcta gaaaatttca tggagagtgt acatttatga atgcaacgat tgtgcaagaa
    66601 aataaattgt tagcagatgg tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt
    66661 tggaaagatt tagatatagc tgtagtcgga attggtgatt ttagcaataa aggaaagcat
    66721 caatggttag acatgcttac agaggatgac tttaaagaat tgaccaaagt taaaactgta
    66781 ggagaaattt gttgtcgatt ttttgattca aaaggtaaag aagtctatga aaacttacag
    66841 gaaagaacga tagcaatctc tttggaagat ttaaaaaata ttcctcaaag tttagctgtt
    66901 gcttacggtg atacgaaagt atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat
    66961 catttgatta cagacaaaaa tacaatttta aaagttttgg aagaagatgg ggatttgact
    67021 tttagagaga ttctaggtga gtgaaaatga tagactgatt cagtttatcg tttttctttt
    67081 tagttgattg cacatttgtg cttatataaa caaaaatagt ttatctgttg tttttggatt
    67141 gacaacttta ttatgtagtt gtattctata gttacaaaag aaaattttaa aatttcaaat
    67201 gaaaaaagct ttttacatag tgaaatgagg aggaatttat ggaaattatt gttccagatc
    67261 aaattatcat gggtttaatt ttatatgctg gtgatgcgaa acaacatatt tataaagcgt
    67321 tagattacat aaaaaatggt acatgtgaac ggtgtgaaga agaaatccag ttagctgatg
    67381 ccgccttatt agaagcccat aatctacaaa caaaattctt ggcacaagaa gcgtctggta
    67441 caaagacaga aattacagct ctctttgttc attcacaaga tcatctcatg actagtatga
    67501 cggagattaa tttaatcaaa gaaattatta gtttgagaaa agaacttcat aaaaaataat
    67561 actagagtat tatcattgtt attaacatag aggaggaaaa cataatggtg aagattggtt
    67621 tgttttgtgc agcaggtttt tctactggta tgcttgtaaa taatatgaaa attgcagcgc
    67681 aatctagtgg agttgaggca gaaatagagg cgttttctca gtctaaatta gcggattatg
    67741 cgccaaatat agatgttgca ctattgggtc cacaagttgc ttatacatta gataaatcaa
    67801 aagaaatttg tgataagtgt gatgttccga tagctgttat tccgatgatg gactatggta
    67861 tgttagatgg gaaaaaagta ttagatttgg ccctatcttt gattagtggg taagaaaagg
    67921 agatttatta tgtcaaagat ggatgttcag aaaatcattg caccgatgat gaagtttgtg
    67981 aatatgcgtg gcattatagc tctaaaagat gggatgttag caattttgcc attgacagta
    68041 gttggtagtt tgttcttgat tatgggacaa ttgccgttcg aaggattaaa taagagcatt
    68101 gctagtgttt ttggagctaa ttggacagag ccgtttatgc aagtatattc aggaactttt
    68161 gctattatgg gtctaatttc ttgtttttca attgcctatt cttatgctaa gaatagcgga
    68221 gtagaggctt taccagctgg agttctatct gtatctgcat tctttatttt gctaagatca
    68281 tcttatatcc ctaaacaagg tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga
    68341 ggccaaggaa ttatcggtgc tatcattata ggtttggtag taggaagtat ttataccttc
    68401 tttataaaga gaaagattgt tattaagatg ccagaacaag ttccacaagc tattgccaaa
    68461 cagtttgaag caatgattcc agcatttgta attttcttat cttctatgat tgtatatatt
    68521 ttagcgaagt cattgactaa tggcggaaca ttcatagaaa tgatttattc tgctattcaa
    68581 gttccgttgc aaggtttaac tggatctttg tatggtgcta ttggaattgc attctttata
    68641 tcatttttgt ggtggtttgg tgttcatggg caatcggtag taaatggagt agtgacagct
    68701 cttcttttat ctaatcttga tgctaataaa gctatgttag cctctgctaa tctatcatta
    68761 gaaaatggag cacatattgt tactcaacag tttttagatt catttttaat tctatcaggt
    68821 tcagggatta cgtttggtct tgtagttgcc atgctttttg cagcaaaatc aaaacaatac
    68881 caagccttag gaaaagttgc agcttttcca gcaatattta acgtaaatga gccagttgta
    68941 tttggatttc cgattgtcat gaatccagtt atgtttgtac ctttcattct tgttcctgta
    69001 cttgcagctg tgatagtata tggagctatt gcaacaggtt tcatgcagcc attctcaggg
    69061 gtaacattgc cttggagtac accagctatt ctatcaggat ttttggtggg tggatggcaa
    69121 ggtgttgtga ctcagttatt agtattggtg atatctacag tggtttactt tccattcttt
    69181 aagatacaag atcgtttagc ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt
    69241 gttactgtta aactcacaca tttgtgctaa aaattagaga gttaaaattt ttctagttaa
    69301 aagcttgaaa atttctataa aaatcggtat tatattttcg aaagaaataa aaatattttc
    69361 gaaagaaagg tgcttacgat ggtaaataca gaagtagcaa gaacaacaat caagacagaa
    69421 tattttggca gccttactga aaggatgaac aaatatcgag aagatgtttt aaataaaaaa
    69481 ccttatattg atgctgagag agcagttcta gcaacacgcg cctatgaacg atacaaggaa
    69541 caacctaatg tcctaaaacg tgcatatatg ctgaaagaaa ttttggaaaa tatgtctatc
    69601 tatattgaag aagaatctat gattgcggga aatcaagctt cttccaataa agatgctcct
    69661 atttttccgg aatatacgct agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt
    69721 gatggagatg ttttctatat tacagaagaa acaaaagaac aacttagaag tattgctccg
    69781 ttttgggaaa ataataattt acgtgctaga gctggtgcct tattacctga agaagtgtct
    69841 gtttatatgg aaacaggatt cttcggtatg gaaggtaaga tgaattctgg agatgctcac
    69901 ttagcagtta actatcagaa acttttgcaa tttggtttaa gaggttttga agagcgggct
    69961 cgtaaagcaa aagtagctct agatttaaca gatccagcaa gtattgataa atatcatttt
    70021 tacgactcta tatttatcgt aatcgatgct attaaagtat atgcaaagcg ctttgttgct
    70081 cttgctaaaa gtttagccga aaatgcaaat cctaaacgta agaaagaatt acttgagatt
    70141 gcagatattt gctctagagt cccatatgaa ccggcaacta cttttgcaga agctattcaa
    70201 tcagtttggt ttattcaatg tattttacaa attgaatcta atggccactc tctttcatat
    70261 ggccgttttg atcaatatat gtatccatat atgaaggctg atttagaaag tggtaaagaa
    70321 acagaagata gcattgttga acgtctgaca aatctttgga ttaagacaat tacaattaat
    70381 aaggttcgca gtcaatcaca tacattttct tcagcaggaa gtcctttata tcaaaatgtt
    70441 acaattggtg gacagactcg agataagaag gatgctgtta acccattatc ttatttggtc
    70501 ttaaaatcag ttgcacaaac ccatctaccg caacctaatc taactgtacg ttaccatgca
    70561 ggtttagatg ctcgtttcat gaatgagtgt attgaagtga tgaaacttgg ttttggtatg
    70621 cctgcattta ataatgatga gattattatt ccttctttta ttgcaaaagg agtattggaa
    70681 gatgatgctt atgattacag tgccattgga tgtgttgaaa cggcagttcc agggaaatgg
    70741 ggctatcgtt gcacaggtat gagttatatg aacttcccta aggttctact tatcacgatg
    70801 aatgatggaa ttgatccggc ttcgggtaaa cggtttgcac caagctttgg tcattttaag
    70861 gatatgaaga acttttctga attagaaaat gcttgggata aaacactaag atatttgaca
    70921 cgaatgagtg ttattgttga aaattctatt gatttatcat tggaacgaga agttcctgat
    70981 attctatgtt cagcattgac tgatgattgt attggtcgtg gaaaacacct taaagaaggt
    71041 ggagcagtat atgattatat atcaggattg caagttggaa ttgcaaattt gtcggattca
    71101 ttagctgcaa ttaaaaaatt ggtgtttgag gaagaacgta taagcccaag tcagctttgg
    71161 catgcactgg aaacagatta tgccggagaa gaaggtaagg tcattcaaga aatgttgatt
    71221 catgatgcac ctaagtatgg taatgatgat gattatgctg acaaattggt tactgctgct
    71281 tatgacattt atgttgatga aattgctaaa tatcctaata cacgttatgg aagagggcct
    71341 attggaggaa ttcgttattc aggaacatct tctatatcag ccaacgtagg gcagggacgt
    71401 ggaacattag caactccaga tggacgcaac gcgggtacac cgttagcaga gggttgttca
    71461 ccatcacata atatggatca acacggccct acatctgttt taaaatctgt ttcaaaatta
    71521 ccaacagatg aaatcgtagg tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta
    71581 gccaaagaag aagataaatt aaaactaatt gctttgttac gaacattctt taatcgttta
    71641 catgggtacc atattcaata caatgttgtt tccagagaga cgttgattga cgctcagaaa
    71701 catcctgaaa aacacagaga cttaattgtt cgtgttgcag gatactctgc attcttcaat
    71761 gttctttcta aggcaaccca agatgacatt ataggacgta ctgagcatac tttgtaaaat
    71821 aaagaggttc tttttatgga atttatgctt gacacattaa atttagatga gattaaaaag
    71881 tggtctgaaa ttttgccgct agctggggta acttcaaatc ccactattgc aaaaagagag
    71941 ggttctatta atttttttga acgaatcaaa gatgtaagag aattgattgg ctccacaccc
    72001 tctattcatg ttcaggtgat ttctcaagat tttgaaggca tcttaaagga tgctcatgaa
    72061 attcgaagac aagcaggaga tgatatattt atcaaagtac ctgttactcc agctggatta
    72121 cgtgcaataa aggtgctaaa aaaagagggc taccatatca ctgcaacagc tatttataca
    72181 gttattcagg gattattagc tatcgaagta ggagcggatt acctagctcc atattataat
    72241 agaatggaaa atctgaacat tgattcaaat tctgtcattc gtcaattagc tcttgctatt
    72301 gatagacaga actctcctag taagatttta gctgcatcct ttaaaaatgt agcacaagta
    72361 aataatgctt tagctgcagg tgcgcatgct gttacagcag gagcagatgt ttttgaatca
    72421 gctttcgcca tgccatctat ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt
    72481 actcaaaata gtcgttccat ttagatagag aggaaataca tatgagaatt tttgctagtc
    72541 cttctagata tattcagggg gaaaatgcct tgtttgaaaa tgccaaatca attttggatt
    72601 tgggaaatta cccgattcta ttatgcgatc agttggttta tgatattgtt ggaaaacgat
    72661 ttgaagatta tctacatagg tatggtttcc atattgttct ggcgctattt aatggtgaag
    72721 cttctgacaa tgaaatcaat cgagttgttg ccttggctga gaaagaaaat tgtgatagta
    72781 ttatcggtct tggtggggga aagacgattg atagcgcaaa agctattgca gatttgattg
    72841 aaaagcctgt tattattgct ccaacaattg catcgaccga cgcacctgta tctgctttat
    72901 ctgttattta tacagatgaa ggtgcatttg atcattatct attttattct aaaaatccag
    72961 atttagtttt ggttgataca aaagttattt cacaagcccc taagcgttta ttagcgtctg
    73021 gtattgcaga tggtttagca acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa
    73081 aaactatgtt gggacaacag caaacattgg ctggagttgc aattgcgaag aaatgtgaag
    73141 aaacgctgtt tgcagatggt ttacaggcta tggcagcttg tgaagctaaa gtggtgacac
    73201 cagcattaga aaacattgtt gaagctaata ctttattgag tggtttaggt tttgaaagtg
    73261 gaggattagc tgcggcgcat gcaattcata atggttttac tgcattgaca ggtgacattc
    73321 atcatttaac acatggtgaa aaagtagctt atggaacttt agtacaacta ttattggaaa
    73381 atagacctaa agaagaactt gataagtata ttgagtttta caaaaaaatt ggtatgccaa
    73441 caactctaaa agaaatgcat ttggatcaag ttggatatga tgatttaata aaagttggta
    73501 aacaagcaac tatggagggt gagacaattc atcagatgcc gtttaagatt tcgccttcag
    73561 atgttgctca agctattatc gctgtagatg cctatgtaaa ttcaaaataa acaataagga
    73621 ctactgtttt ccaaatggta gtcttttatt gatcctcgta ttgaattcta tagcagattg
    73681 aaataagatg agaacaaatc gattgggaaa gtaaaattaa tttctataag tgttttagca
    73741 attgtttcgt actatttcag attcagtcca ctatacgttc ttcataaatc aaaaagcgac
    73801 ataggttgtc ggctatttat tgtgaataca ttaattagca ttccagtttt atcttcggtc
    73861 taaagtaagt attttgtgct atacgagata agcgtcttga cttactcctt gatttactgc
    73921 ataacaatgg gataaaaagt gggagataga gcaattcata gtcatcaaaa ttaatgagat
    73981 acagtataca gttttttctt taaacacatt tcaaattccc tcaaaaatgg tataatagta
    74041 acatcacaaa attggagaga gaccatgagt ttttataatc ataaagaaat tgagcctaag
    74101 tggcagggct actgggcaga acatcataca tttaagacag gaacagatgc atcaaaacct
    74161 aagttttatg cgcttgatat gttcccttat ccgtctggag ctggtctgca tgtaggacac
    74221 ccagaaggtt atactgcaac cgatatcctc agtcgttaca aacgtgcgca aggctacaat
    74281 gtccttcacc caatgggttg ggatgctttt ggtttacctg cagagcaata cgctatggat
    74341 actggtaatg acccagcaga atttacagcg gaaaacattg ccaacttcaa acgtcaaatc
    74401 aatgcgcttg gattttctta tgactgggat cgtgaagtca acacaacaga tccaaactac
    74461 tacaagtgga ctcaatggat tttcaccaag ctttacgaaa aaggcttggc ctatgaagct
    74521 gaagtgccag taaactgggt tgaggaattg ggaactgcca ttgccaatga agaagtgctt
    74581 cctgacggaa cttctgagcg tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg
    74641 atgctcaaaa tcacggctta cgcagagcgc ttgctcaatg acttagatga actagattgg
    74701 tcagagtcta tcaaggatat gcaacgcaac tggattggta aatcaactgg tgccaatgta
    74761 actttcaaag taaaaggaac agacaaggaa tttacagtct ttactactcg tccggacaca
    74821 cttttcggtg cgactttcac tgtcttggct cctgaacatg aattagtaga cgctatcaca
    74881 agttcagagc aagcagaagc tgtagcagac tataaacacc aagccagcct taagtctgac
    74941 ttggctcgta cagaccttgc taaggaaaaa actggtgttt ggacaggtgc ctatgccatc
    75001 aaccctgtca atggtaagga aatgccaatc tggattgcgg actatgttct tgctagttat
    75061 ggaacaggtg cggttatggc tgtgcctgcc cacgaccaac gtgactggga atttgccaaa
    75121 caatttgacc ttccaatcgt cgaagtactt gaaggtggag atgtcaaaga agctgcctac
    75181 acagaggatg gcctgcatgt caattcagac ttcctagatg aactcaacaa agaagacgct
    75241 attgccaaga ttgtggcttg gttggaagaa aaaggctgtg gtcaggagaa ggttacctac
    75301 cgtctccgcg actggctctt tagccgtcaa cgttactggg gtgagccaat tccaatcatt
    75361 cattgggaag atggaacttc aacagctgtt cctgaaactg aattgccgct tgtcttgcct
    75421 gtaaccaagg atatccgtcc ttcaggtact ggtgaaagtc cactagctaa cttgacagat
    75481 tggcttgaag tgactcgtga agatggtgtc aaaggtcgtc gtgaaaccaa cactatgcca
    75541 caatgggctg gttcaagctg gtactacctc cgctatattg atccacacaa tactgagaaa
    75601 ttggctgatg aggacctcct caaacaatgg ttgccagtag atatctacgt gggtggtgcg
    75661 gaacatgctg tacttcactt gctttacgct cgtttctggc acaaattcct ctatgacctc
    75721 ggtgttgttc cgactaagga accattccaa aaactcttta accaagggat gattttggga
    75781 acaagctacc gtgaccaccg tggtgctctt gtggcaaccg acaaggttga aaaacgtgat
    75841 ggttccttct ttcatgtaga aacaggggaa gagttggagc aagcgccagc caagatgtct
    75901 aaatcgctca agaacgttgt taacccagac gatgtggtgg aacaatacgg tgccgatacc
    75961 cttcgtgttt atgaaatgtt tatgggacca ctcgatgctt cgattgcttg gtcagaagaa
    76021 ggtttggaag gaagccgtaa gttccttgac cgagtttacc gtttgattac aagtaaagaa
    76081 atccttgcgg aaaacaatgg tgctcttgac aaggtttaca acgaaacagt caaagctgtt
    76141 actgagcaaa ttgagtctct caaattcaac acagctattg cccaacttat ggtctttgtc
    76201 aatgctgcta acaaggaaga taagctttat gttgactatg ccaaaggctt tattcaattg
    76261 attgcaccat ttgcacctca cttggcagaa gaactctggc aaacagtcgc agaaacaggt
    76321 gagtcaatct cttatgtagc ttggccaact tgggacgaaa gcaaattggt tgaagatgaa
    76381 attgaaattg tcgtccaaat caaaggaaaa gtccgtgcca aactcatggt tgctaaagat
    76441 atatcacgtg aagaattaca agaaatcgct ttagctgatg aaaaagtcaa agcagaaatt
    76501 gacggtaagg aaatcgtgaa agtaattgcg gtaccgaata aactcgttaa tatcgtcgtt
    76561 aaataacgag tttattagct ctatctgcca ccttcaatag tccactggac tattgaagcc
    76621 aactaaatta gttaacattg ttgtgaaata agataggaat ccttcagagt agaatctgga
    76681 ggattttttg aaccttctta tgaaagtat
//
LOCUS       DBEJZJ010000006        73826 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000006 DBEJZJ010000000
VERSION     DBEJZJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.06"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..662
                     /locus_tag="ACL3R8_000487"
                     /pseudo
     CDS             1..662
                     /locus_tag="ACL3R8_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(790..1038)
                     /locus_tag="ACL3R8_000488"
     CDS             complement(790..1038)
                     /locus_tag="ACL3R8_000488"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313427.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(986..2068)
                     /locus_tag="ACL3R8_000489"
     CDS             complement(986..2068)
                     /locus_tag="ACL3R8_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR1313428.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2194..2976)
                     /gene="gatD"
                     /locus_tag="ACL3R8_000490"
     CDS             complement(2194..2976)
                     /gene="gatD"
                     /locus_tag="ACL3R8_000490"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR1313429.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2976..4319)
                     /gene="murT"
                     /locus_tag="ACL3R8_000491"
     CDS             complement(2976..4319)
                     /gene="murT"
                     /locus_tag="ACL3R8_000491"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR1313430.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGTTQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4418..5734)
                     /locus_tag="ACL3R8_000492"
     CDS             complement(4418..5734)
                     /locus_tag="ACL3R8_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR1313431.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5928..7154
                     /locus_tag="ACL3R8_000493"
     CDS             5928..7154
                     /locus_tag="ACL3R8_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR1313432.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7353..8927
                     /locus_tag="ACL3R8_000494"
     CDS             7353..8927
                     /locus_tag="ACL3R8_000494"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1313433.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9191..9979
                     /gene="codY"
                     /locus_tag="ACL3R8_000495"
     CDS             9191..9979
                     /gene="codY"
                     /locus_tag="ACL3R8_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR1313434.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9979..10554
                     /locus_tag="ACL3R8_000496"
     CDS             9979..10554
                     /locus_tag="ACL3R8_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR1313435.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10636..10721
                     /locus_tag="ACL3R8_000497"
     tRNA            10636..10721
                     /locus_tag="ACL3R8_000497"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10670..10672,aa:Leu,seq:aag)
     gene            10994..12124
                     /locus_tag="ACL3R8_000498"
     CDS             10994..12124
                     /locus_tag="ACL3R8_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313436.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12625..13383
                     /locus_tag="ACL3R8_000499"
     CDS             12625..13383
                     /locus_tag="ACL3R8_000499"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1313437.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMRLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13470..13982
                     /locus_tag="ACL3R8_000500"
     CDS             13470..13982
                     /locus_tag="ACL3R8_000500"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR1313438.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14164..15108
                     /gene="metA"
                     /locus_tag="ACL3R8_000501"
     CDS             14164..15108
                     /gene="metA"
                     /locus_tag="ACL3R8_000501"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR1313439.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            15117..15794
                     /locus_tag="ACL3R8_000502"
     CDS             15117..15794
                     /locus_tag="ACL3R8_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR1313440.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15892..16650
                     /gene="tpiA"
                     /locus_tag="ACL3R8_000503"
     CDS             15892..16650
                     /gene="tpiA"
                     /locus_tag="ACL3R8_000503"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR1313441.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVVSKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16688..18193
                     /gene="lytC"
                     /locus_tag="ACL3R8_000504"
     CDS             16688..18193
                     /gene="lytC"
                     /locus_tag="ACL3R8_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR1313442.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGTRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18689..19207
                     /locus_tag="ACL3R8_000505"
     CDS             18689..19207
                     /locus_tag="ACL3R8_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR1313443.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19337..19843
                     /locus_tag="ACL3R8_000506"
     CDS             19337..19843
                     /locus_tag="ACL3R8_000506"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR1313444.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19843..20013
                     /locus_tag="ACL3R8_000507"
     CDS             19843..20013
                     /locus_tag="ACL3R8_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313445.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20045..21277
                     /gene="clpX"
                     /locus_tag="ACL3R8_000508"
     CDS             20045..21277
                     /gene="clpX"
                     /locus_tag="ACL3R8_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR1313446.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21286..21873
                     /gene="yihA"
                     /locus_tag="ACL3R8_000509"
     CDS             21286..21873
                     /gene="yihA"
                     /locus_tag="ACL3R8_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR1313447.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21884..22264
                     /locus_tag="ACL3R8_000510"
     CDS             21884..22264
                     /locus_tag="ACL3R8_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR1313448.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22316..23206
                     /gene="rapZ"
                     /locus_tag="ACL3R8_000511"
     CDS             22316..23206
                     /gene="rapZ"
                     /locus_tag="ACL3R8_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR1313449.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23203..24180
                     /locus_tag="ACL3R8_000512"
     CDS             23203..24180
                     /locus_tag="ACL3R8_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR1313450.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQAILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24177..25088
                     /gene="whiA"
                     /locus_tag="ACL3R8_000513"
     CDS             24177..25088
                     /gene="whiA"
                     /locus_tag="ACL3R8_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR1313451.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25122..26087)
                     /locus_tag="ACL3R8_000514"
     CDS             complement(25122..26087)
                     /locus_tag="ACL3R8_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR1313452.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26223..27080
                     /gene="cdaA"
                     /locus_tag="ACL3R8_000515"
     CDS             26223..27080
                     /gene="cdaA"
                     /locus_tag="ACL3R8_000515"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR1313453.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27067..27846
                     /locus_tag="ACL3R8_000516"
     CDS             27067..27846
                     /locus_tag="ACL3R8_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR1313454.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27870..29222
                     /gene="glmM"
                     /locus_tag="ACL3R8_000517"
     CDS             27870..29222
                     /gene="glmM"
                     /locus_tag="ACL3R8_000517"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR1313455.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KTIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTIEEVDYYVDTITDVVRAEIGID
                     "
     gene            29296..29670
                     /locus_tag="ACL3R8_000518"
     CDS             29296..29670
                     /locus_tag="ACL3R8_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR1313456.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29672..30520
                     /locus_tag="ACL3R8_000519"
     CDS             29672..30520
                     /locus_tag="ACL3R8_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1313457.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30786..31553
                     /gene="dapB"
                     /locus_tag="ACL3R8_000520"
     CDS             30786..31553
                     /gene="dapB"
                     /locus_tag="ACL3R8_000520"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR1313458.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31550..32749
                     /locus_tag="ACL3R8_000521"
     CDS             31550..32749
                     /locus_tag="ACL3R8_000521"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR1313459.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            32746..34617
                     /locus_tag="ACL3R8_000522"
     CDS             32746..34617
                     /locus_tag="ACL3R8_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1313460.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMSRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34760..35944)
                     /gene="mntE"
                     /locus_tag="ACL3R8_000523"
     CDS             complement(34760..35944)
                     /gene="mntE"
                     /locus_tag="ACL3R8_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR1313461.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36248..38944
                     /locus_tag="ACL3R8_000524"
     CDS             36248..38944
                     /locus_tag="ACL3R8_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR1313462.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38957..39748
                     /gene="yghU"
                     /locus_tag="ACL3R8_000525"
     CDS             38957..39748
                     /gene="yghU"
                     /locus_tag="ACL3R8_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR1313463.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39864..40274
                     /locus_tag="ACL3R8_000526"
     CDS             39864..40274
                     /locus_tag="ACL3R8_000526"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR1313464.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40286..41881
                     /locus_tag="ACL3R8_000527"
     CDS             40286..41881
                     /locus_tag="ACL3R8_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313465.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            42048..42212
                     /locus_tag="ACL3R8_000528"
     CDS             42048..42212
                     /locus_tag="ACL3R8_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR1313466.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            42291..43019
                     /gene="yaaA"
                     /locus_tag="ACL3R8_000529"
     CDS             42291..43019
                     /gene="yaaA"
                     /locus_tag="ACL3R8_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR1313467.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(43297..43845)
                     /locus_tag="ACL3R8_000530"
     CDS             complement(43297..43845)
                     /locus_tag="ACL3R8_000530"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR1313468.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            44166..44654
                     /locus_tag="ACL3R8_000531"
     CDS             44166..44654
                     /locus_tag="ACL3R8_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR1313469.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEKADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44651..45838
                     /locus_tag="ACL3R8_000532"
     CDS             44651..45838
                     /locus_tag="ACL3R8_000532"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1313470.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45831..46196
                     /locus_tag="ACL3R8_000533"
     CDS             45831..46196
                     /locus_tag="ACL3R8_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1313471.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            46212..47558
                     /gene="asnS"
                     /locus_tag="ACL3R8_000534"
     CDS             46212..47558
                     /gene="asnS"
                     /locus_tag="ACL3R8_000534"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR1313472.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47711..48001
                     /gene="rpsF"
                     /locus_tag="ACL3R8_000535"
     CDS             47711..48001
                     /gene="rpsF"
                     /locus_tag="ACL3R8_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR1313473.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            48013..48483
                     /gene="ssbA"
                     /locus_tag="ACL3R8_000536"
     CDS             48013..48483
                     /gene="ssbA"
                     /locus_tag="ACL3R8_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR1313474.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48515..48754
                     /gene="rpsR"
                     /locus_tag="ACL3R8_000537"
     CDS             48515..48754
                     /gene="rpsR"
                     /locus_tag="ACL3R8_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR1313475.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            49049..50449
                     /locus_tag="ACL3R8_000538"
     CDS             49049..50449
                     /locus_tag="ACL3R8_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR1313476.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50451..50810
                     /locus_tag="ACL3R8_000539"
     CDS             50451..50810
                     /locus_tag="ACL3R8_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR1313477.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50864..51613
                     /locus_tag="ACL3R8_000540"
     CDS             50864..51613
                     /locus_tag="ACL3R8_000540"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR1313478.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51603..51902
                     /locus_tag="ACL3R8_000541"
     CDS             51603..51902
                     /locus_tag="ACL3R8_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR1313479.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51973..52908
                     /locus_tag="ACL3R8_000542"
     CDS             51973..52908
                     /locus_tag="ACL3R8_000542"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR1313480.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52994..53506
                     /locus_tag="ACL3R8_000543"
     CDS             52994..53506
                     /locus_tag="ACL3R8_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR1313481.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53490..54139
                     /locus_tag="ACL3R8_000544"
                     /pseudo
     CDS             53490..54139
                     /locus_tag="ACL3R8_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            54240..54437
                     /locus_tag="ACL3R8_000545"
     CDS             54240..54437
                     /locus_tag="ACL3R8_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR1313482.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(54480..55925)
                     /locus_tag="ACL3R8_000546"
     CDS             complement(54480..55925)
                     /locus_tag="ACL3R8_000546"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR1313483.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISNYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            56031..57653
                     /locus_tag="ACL3R8_000547"
     CDS             56031..57653
                     /locus_tag="ACL3R8_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR1313484.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57856..59814
                     /locus_tag="ACL3R8_000548"
     CDS             57856..59814
                     /locus_tag="ACL3R8_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313485.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     AYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59986..60186
                     /locus_tag="ACL3R8_000549"
     CDS             59986..60186
                     /locus_tag="ACL3R8_000549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313486.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSYWSSLVFFYWLLSV"
     gene            60155..61068
                     /locus_tag="ACL3R8_000550"
                     /pseudo
     CDS             60155..61068
                     /locus_tag="ACL3R8_000550"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            61062..61649
                     /locus_tag="ACL3R8_000551"
     CDS             61062..61649
                     /locus_tag="ACL3R8_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313487.1"
                     /translation="MLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSG
                     SIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRL
                     QIARTYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDC
                     IFFLEEGKITGSGTHKELLENHERYACFVQEQMIE"
     gene            61806..62900
                     /locus_tag="ACL3R8_000552"
     CDS             61806..62900
                     /locus_tag="ACL3R8_000552"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR1313488.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            62908..64074
                     /locus_tag="ACL3R8_000553"
     CDS             62908..64074
                     /locus_tag="ACL3R8_000553"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR1313489.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQIYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            64167..67265
                     /locus_tag="ACL3R8_000554"
     CDS             64167..67265
                     /locus_tag="ACL3R8_000554"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1313490.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQVLVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            67313..67930
                     /locus_tag="ACL3R8_000555"
     CDS             67313..67930
                     /locus_tag="ACL3R8_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR1313491.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            67941..69275
                     /gene="murC"
                     /locus_tag="ACL3R8_000556"
     CDS             67941..69275
                     /gene="murC"
                     /locus_tag="ACL3R8_000556"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR1313492.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            69285..69749
                     /locus_tag="ACL3R8_000557"
     CDS             69285..69749
                     /locus_tag="ACL3R8_000557"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313493.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            69746..70240
                     /locus_tag="ACL3R8_000558"
     CDS             69746..70240
                     /locus_tag="ACL3R8_000558"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313494.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            70321..71976
                     /gene="mltG"
                     /locus_tag="ACL3R8_000559"
     CDS             70321..71976
                     /gene="mltG"
                     /locus_tag="ACL3R8_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR1313495.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            72047..72529
                     /gene="greA"
                     /locus_tag="ACL3R8_000560"
     CDS             72047..72529
                     /gene="greA"
                     /locus_tag="ACL3R8_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR1313496.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            72902..73300
                     /locus_tag="ACL3R8_000561"
     CDS             72902..73300
                     /locus_tag="ACL3R8_000561"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313497.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            73749..73826
                     /locus_tag="ACL3R8_000562"
                     /pseudo
     CDS             73749..73826
                     /locus_tag="ACL3R8_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT        21942 a        13735 c        16705 g        21444 t
ORIGIN      
        1 cgggttcatt tagaactaag aaatcgtggt tatctggtaa atcataaaag agttcaaggc
       61 ttgatgaaag tactcaattt acaaactaaa atgcgacaga aacgaaaata ttcttctcat
      121 aaaggagacg ttggtaagaa ggcagagaat ctcattcaag gccaatttga aggctctaaa
      181 acaatggaaa agtgctacac agatatgaca gaatttgcca ttccagcaag tactcaaaag
      241 ctttacttat caccagtttt agatggcttt aacagcgaaa ttatcgccta taatctttca
      301 acttcaccca acttagaaca agtacaaaca atgttggaac aggcattcac agagaagtac
      361 tacgagaata cgattctcca tagtgaccaa ggctggcaat atcaacacga ttcttatcat
      421 cggttcttag agagtaaggg aattcaagca tccatgtcac gtaagggaaa cagccaagac
      481 aacggtatga tggagtcctt ctttgggatt ctgaaattta tggctatgag aaaacattta
      541 aatcacttaa tcaattggaa caagctattg tagactatat tgattactac aacaataaac
      601 gaattaaggt aaaactaaaa ggacttagtc ctgtgcagta cagaactaaa tcctttggat
      661 aaattaattg tctaactttt ggggggcagt acattttaac acttgataat atgcgtttta
      721 ttgtgggaag attttcctca ttttctagtg aaattgaact ttttctaaca tcttttgata
      781 gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca tcccttgtct
      841 ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta gattattgca
      901 gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta gatattttga
      961 aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg ctggtgcttg
     1021 taaagaggtc gaagccatcc ttggtaacaa caccgcagtc ttcaatacga acaccgactt
     1081 taccagggat atagatacct ggttcaacag agaagcacat gccttcttcg atgaccatgt
     1141 cgtttccttc catgatagat gggaattcat ggacatccat accgatacca tgcccgagac
     1201 ggtggttgaa gtactcacca taaccagctt tttcgatgat ctcacgggca gcgcggtcca
     1261 cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg gcttcaagag
     1321 tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact gtacgagtca
     1381 tatctgacgc atagccattg accagaaccc ccaggtcaaa gaggagaaga gcatcatttt
     1441 caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca gtcaagacca
     1501 tggtatcaaa gctcatttcg taaccttcac gtttcatggc aaagtcaatt tgtgcgatga
     1561 tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca gccttgtcag
     1621 cataaagacc tgcaaccatc attttttgta cttcatcagc tgatttgatg aggcgcatgc
     1681 gttggatacg aggagtgagg ttttcaaact cagcagtttc aaaaattgtt ttcaaaccat
     1741 ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag tcaagttgtg
     1801 gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc actactggga
     1861 aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg agaggttcct
     1921 gatccgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa aaaccagtga
     1981 ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct gattcaagat
     2041 atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct ctattttggc
     2101 aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag
     2161 ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct tgcttttgac
     2221 gtcactgtac tcttcagcga tttcttggct gaggatatcc tcataggcag ggagttggat
     2281 atcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca gattggcatt
     2341 acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat gaaccccttc
     2401 accgaccttt tcttcgttgt ttccatttcc atagacaact tgtcccagcg gtttttggtc
     2461 atcagagagg aaggtacggc cttggtgatt ttcaaatcca tagtaggttt catcgaaatc
     2521 ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga gcgtgtagtg
     2581 tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat attgacccaa
     2641 tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt agttgtcaat
     2701 gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc
     2761 accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag aaacgatgtc
     2821 aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga tgtttccatt
     2881 gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct gataggggta
     2941 attgccatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt tctaacaatc
     3001 tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc cagaatatag
     3061 gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt actcgtttca
     3121 gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc agaatgacga
     3181 acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa gtctgcatcc
     3241 cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac agataggcta
     3301 aatggataag gtgctagttt gatcatttcg atagcttggg ttgtaccgac tggattttta
     3361 atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg tccaaagaca
     3421 gcacggctct tgtcaaatcc ctgtttgatg agttgcgaat cggcacctag gaaacgggcg
     3481 atggccacag cagctagggc gttatatata ttatagagcc cgccgatttg gataccgtat
     3541 tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccaa ttttgtcaaa
     3601 cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc acccaagttt
     3661 gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag aatcccttcg
     3721 gtattgtagt gagccagttg ggctggtcct ttttccaagt caaaaccaaa atactctata
     3781 gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag aacagtagca
     3841 gttggaactt tccgaatggc atccaatatc atgttatagg tagtatagat ttcaccgaaa
     3901 cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg gatatagtca
     3961 cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt tccagtttta
     4021 gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc accgcttggg
     4081 ttggttagaa cttgaccata aacctctttt aaaatgccga cagtgagggc agttgtcagg
     4141 gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag gttttgtaaa
     4201 atatctttat caaattgaag ggcgacttta cctgggagcg tacttccacg tccaagacgg
     4261 cttaaaacga agtgggaaga acgcccagca agaaggccca aagtagtttt taagttcatg
     4321 tttctattat atcacaaaag agggaaaaga cagatttggt gtttcgtaga agtaaaaaca
     4381 gcccaaagag ggctgtcagt taagatgaga tttcaactta aatcgcaaac aagtcattca
     4441 agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg taaggaatct
     4501 tgttgtccat agcaacagta atgatgttga tgatttcttg agaaccttct gagaagatgc
     4561 ttgcaccaag aatttctttt gtttcagtat taacaacagc tttgaaagct ccgcgaaggt
     4621 ctccatttac gtgaccacga ggcatggctg caacagggat ttctttcact gcgtatggaa
     4681 gtttcaaatc agctgcttgg ctttcagtca aaccaacttg tgaaagtgca ggtgtgatga
     4741 acatagtatt tggcacattg agacggtcct caagtgtgta gctgccatct ccagcaaggt
     4801 agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaaga ccaccgttga
     4861 catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttatct actttaatag
     4921 cgccacgttc agttagttca atatctgtat tttcaagttg aagtggttct acatttggtt
     4981 tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca gttacgacaa
     5041 gcacttggtc accgtcgttt ttaatttcag tagtatggat attttgaagc aattcaatac
     5101 cgtcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca cgaggtagga
     5161 atgtatccaa ggcatctagg actgtaacct tgcttcctag tttattgtaa aggccagcaa
     5221 attcaagacc gatatttccg ccaccaagga ctccaagttt ttcaggcaat ttatccaagc
     5281 tttggatacc tgttgagtca aagacgtttt tgcttgtagc aagtccaggg attggcaaga
     5341 cgtttgaaac agcaccagtg ttgatgacga tagtttcagc agtcaattct tgtttttcat
     5401 caccagcttg gatttcgatg actttatttg aaaggaagtg agcttcagca tcaaagatat
     5461 tgacgccagt accagcaaca gtcgtatagt ttttaccgtt gaggcgacca gtgatcgtgt
     5521 ttttggtagc aatgacttct tcaaaagaca agtctttctc agcagcaacc agcaaagttt
     5581 tagttgggat acaaccgatg ttgatacaag ttccaccgta catagctttg ctacgttcaa
     5641 cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta ccagctttac
     5701 caaatccgat aacgattaaa tcataagtta acatttagag ttcctcctat tcgcatttca
     5761 ttctagcaca agaaaaaaac ttttgcacaa ttctgctacg gaaaagacag aaaaagataa
     5821 aaacgctttc cagacaaaaa actagtaatt ttttgacaag cttgataaac taaaatccta
     5881 tctattttta tataagatag aaaaaatgtt cgaaaatagg aggttttatg aaatcgaatc
     5941 gttatattat tgcctttgct ggggtcattt tacacttaat gctgggttcg acttatgctt
     6001 ggagtgttta tcgtaaccct attattgaaa aaacgggatg ggatcaggct tctgttgcct
     6061 ttgcctttag tctagcaatc ttttgtttgg gcttatcggc tgcatttatg gggcgtttgg
     6121 tagaaaaatt tggtccgaga gtcatgggga gtctatctgc ttttctatac gcaggtggaa
     6181 atatcttaac aggatttgca atagaccgtc aggaactgtg gttgttgtat ctagcttatg
     6241 gcattttagg tgggcttggt ttgggagcag gctatattac ccctgtgtca acgattataa
     6301 aatggtttcc tgataaacgt ggtctcgcaa caggtttagc gattatgggg tttggttttg
     6361 cttctttatt gactagtccc atagcgcaac atctcatcgc aggggtaggg cttgtagaaa
     6421 ctttttatat tttaggtgca agttacttta ttatcatgct cctagcttca caattcatta
     6481 agcgtccaaa tgagcaagag cttgcaattt tatctgcttc agggaaagaa aaaacagact
     6541 ctctgacgca agggatgact gcaaatcagg ctctaaaaag caatcggttt tatatgcttt
     6601 ggattatttt ctttatcaac atagcttgtg gtttaggctt aatttcagcg gcatcgccaa
     6661 tggcacagga gatggctggc ttgtctacaa gtcatgcagc agtaatggtg ggtattttgg
     6721 ggattttcaa tggatttggt cgcttgctct gggcgagttt gtctgactat atcggtcgcc
     6781 ctctaacctt tagtatatta ctgcttgtca atcttttctt ttctctctca ctttggctct
     6841 ttacagattc cgttttattt gtagttgcta tgtctatttt gatgacttgc tatggagctg
     6901 gtttttcttt gattccagct tatctcagtg atatttttgg aaccaaggaa ttggccgctc
     6961 tgcatggtta tattttaaca gcttgggcaa tggctggttt agcgggacct attttattag
     7021 cagagactta taaaatggct cattcgtaca cacaaacctt gttcgttttt ctcattttat
     7081 acagtatcgc cttggctttg tcttattatc taggtcgttc aatcaaaaaa gaaagtcaaa
     7141 aaccgcttac atgattttct gtagaaatgg ggctatcttt tgctctggtc ttgtgttata
     7201 ctagataggt tgcaaagaaa acagtacttt tcttttgtgg aaaagaagca acacgatttt
     7261 atatctagtt atatgaaaat acgtcataaa aagaaaagta taaactaagc cctatagggt
     7321 ggcttcgcac cacctttaga aagaagaata acgtgaaatt taatgaatta aacttgtctg
     7381 ctgatttgct agcagaaatt gaaaaagctg gttttgtaga agctagtcct atccaagaac
     7441 aaactattcc tttggccctt gaaggcaagg atgttatcgg tcaagctcag actggtacag
     7501 gaaaaactgc agcctttggc ttgcctaccc ttgaaaaaat ccgtacagaa gaagcgacta
     7561 tccaagcttt ggtcatcgct ccaactcgtg aactagctgt ccaaagtcaa gaagaactct
     7621 tccgctttgg tcgtagtaag ggagtcaaag tccgttcagt atatggcgga tcaagcattg
     7681 aaaaacaaat taaggctctt aaatctggtg cccatatcgt ggtgggaact ccaggtcgcc
     7741 tcttggactt gattaaacgc aaggccttga aattacaaga cattgaaacc cttatccttg
     7801 acgaagcgga tgaaatgctt aacatgggct tccttgaaga catcgaagcc attatttccc
     7861 gtgtacctga gaaccgtcaa actttgcttt tctcagcaac tatgccagat gccatcaaac
     7921 gtatcggtgt tcagtttatg aaagcccctg aacatgtcaa gattgcggct aaggaattga
     7981 caacagaatt ggttgaccag tactatatcc gtgttaagga acaagaaaaa tttgacacca
     8041 tgactcgtct catggatgtg gcacaaccag aactcgctat tgtatttggt cgtaccaaac
     8101 gccgtgtgga tgaattgact cgtggtttga aaattcgtgg cttccgtgca gaaggaattc
     8161 atggcgacct agaccaaaac aaacgtcttc gtgtccttcg tgactttaaa aatggcaatc
     8221 ttgatgtttt ggttgcgaca gacgttgcag cgcgtggttt ggatatttca ggtgtgaccc
     8281 atgtctacaa ctacgatatt ccacaagatc ctgagagtta tgttcaccgt atcggtcgta
     8341 caggtcgtgc tggtaagtca ggtcaatcta ttacttttgt tgctccaaac gaaatgggtt
     8401 accttcaaat cattgaaaac ttgactaaga aacgcatgaa aggtctcaaa cctgcaagtg
     8461 tagaagaatc cttccaatca aaaaaacagg tagctctcaa gaaaatcgaa cgtgattttg
     8521 cagatgaaac cattcgtgcc aactttgaga aatttggtaa ggatgctcgc aaattggctg
     8581 ctgagtttac tccagaagaa ttggcaatgt atatcttgag tctgacagtc caagacccag
     8641 atagccttcc agaagtggag attgcacgtg aaaaaccact accgtttaaa ccatcaggta
     8701 atggtttcgg tggtaaagct aagggaggtc gtggaggccg tcgtggggac gaccgtcgag
     8761 agcgtgatcg ccgtggcaat ggtcgccgtg atgagttcaa aaaaggaagt cgtggcaacg
     8821 atcgttttga taaggaaaaa cgttaccgta aggataataa aaaaccacgc aatactttaa
     8881 gcgaaaagca aacaggcttt gttattcgta acaagggcga taaataagaa aaagcggttc
     8941 aaaatgaatc gcttttttat ataaggagac cgaatgtgaa aagacaaata aaattattat
     9001 attatctttt ataatgttat gatacacaaa aataggcaac ttgtcaatag aaaaggaaca
     9061 atttaattaa aaatattctg gtttttaatt aaattgtaag tcaatgcaag tcaataagga
     9121 attttcagat aattattgaa aaagagacgt ttttatgtta taatgatagc gattaaattc
     9181 gaggtgaaaa atggcacatt tattagaaaa aactagaaaa attacatcaa ttttgaaacg
     9241 ctcagaggag cagttgcagg atgagctccc ttacaacgct attacgcgtc agttagcgga
     9301 tattattcat tgcaatgcct gcattatcaa tagtaaggga cgtctgcttg gctattttat
     9361 gcgttataaa acaaatacag atcgcgtaga gcaattcttc caaactaaga ttttcccaga
     9421 tgactacgtt caaggggcta atatgattta cgaaacagaa gcaaacttgc ctgttgagca
     9481 tgatatgagt attttccctg ttgagagtag agatgatttt ccagatggct tgacgactat
     9541 tgcaccgatt catgtatcgg ggattcgcct tggttctttg attatttggc gtaatgataa
     9601 aaaattcgaa gatgaggact tggttcttgt tgagattgcc agtaccgttg ttgggattca
     9661 gcttcttaac ttccaacgtg aagaagatga gaaaaatatt cgtcgtcgta ctgctgtcac
     9721 catggcggtc aatacccttt cttactccga actccgtgct gtttcagcaa ttttagggga
     9781 attaaatgga aatgaaggga agttgactgc gtcagtgatt gcagatcgta tcggaatcac
     9841 tcgctctgtg attgtcaatg ctcttcgtaa acttgagtct gcggggatta ttgaaagtcg
     9901 ctcacttgga atgaagggaa cctatcttaa ggtcttgatt tcagatattt ttgaagaagt
     9961 gaagaaaaga gattactaat gacaaaggct ttaatttcga ttgattatac agaagatttt
    10021 gttgctgata gtgggaagct gacagcaggt gctccagctc aggcgatttc ggatgccatc
    10081 agcaaggtaa ctcgattagc ttttgaacga ggagattata tcttctttac tattgatgct
    10141 catgaagaaa acgatttttt ccatccggaa agtaagttat ttcctcctca taatctgatt
    10201 gggacgagtg gacggaattt atatggagat ttggggatct tttatcaaga gcatggttca
    10261 gacagtcgtg tcttttggat ggataaacgc cattactcag ctttttcagg gactgaccta
    10321 gatattcgtt tgagagagcg tagagtgtct accgttatct taacaggtgt cttgacggat
    10381 atctgtgtcc tacatacagc tatagatgcc tataatctag gatatgacat cgagattgtt
    10441 aaaccagctg ttgcttccat ctggcctgaa aatcatcaat ttgccctagg tcatttcaaa
    10501 aatacactcg gagctaagtt agtagatgaa aatctaaatg aactttctga gtaacctggt
    10561 tggtgaaaat gaaaaaattt gaaaaaaagt gttgacaagc atcccaaaag ttgatatact
    10621 agtaaagtaa tcgatgcggg gatggcggaa ttggcagacg cgcaggacta aggatcctgt
    10681 gaccgcttta ggtcgtgagg gttcaagtcc ctctctccgc ataggaaaag agttagctaa
    10741 agctagctct tttgtatttc tctaaaaaat tagaatccag tcaaatgtag tggagaatca
    10801 gcgaaaatat gggaaaactg atccttgttt ctgcttttgt catagaagaa taataaattc
    10861 aaattctccg atattctcta aagttttgtg caagttgcac agaacttttt tatttttttg
    10921 gtcatcttgc catagaaata taaagcgttt tcatctataa tataattatc aaaagacaaa
    10981 aggagttcac ctcatggtag aattgaatct taaaaatatt tacaaaaaat atccaaacag
    11041 cgaacactat tcagttgaag atttcaactt gaacatcaaa gataaagaat ttatcgtttt
    11101 cgtaggacct tcaggatgtg gtaaatcaac tacactccgt atgattgctg gtcttgaaga
    11161 cattacagaa ggtactgcat ctatcgatgg cgtggttgtc aacgacgtag ctccaaaaga
    11221 ccgtgatatc gccatggtat tccaaaacta cgctctttac ccacacatga ctgtttatga
    11281 caacatggct ttcggtttga aattgcgtaa atacagcaaa gaagacatta acaaacgtgt
    11341 tcaagaagca gctgaaatac ttggattgaa agaattcttg gaacgtaaac cagctgacct
    11401 ttcaggtggt caacgtcaac gtgttgccat ggggcgtgcg attgtccgtg atgcgaaagt
    11461 attcttgatg gacgaacctt tgtcaaactt ggatgccaaa cttcgtgtat caatgcgtgc
    11521 tgaaatcgct aaaattcacc gtcgtatcgg agctacaact atctatgtaa ctcacgacca
    11581 aacagaagcg atgacacttg cagaccgtat cgttattatg tcagctacta agaaccctgc
    11641 tggtacaggt actatcggac gtgtagaaca aatcggtact cctcaagaag tttacaaaaa
    11701 tccagttaac aaatttgttg caggattcat cggaagccca gctatgaatt tcatcaacgt
    11761 gaaattggtt ggtagcgaaa ttgtttctga cggtttccgt ttgaaagtgc cagaaggagc
    11821 attgaaagtt cttcgtgaaa aaggctacga aggaaaagaa ttgatctttg gtatccgtcc
    11881 agaagacgtg aatgcagaac ctgctttcct tgaaacattc ccagactgtg ttgtaaaagc
    11941 gactatctct gtatcagaac tgcttggttc agaatctcac ctttactgcc aagttggtaa
    12001 agacgagttt gttgcaaaag ttgatgctcg tgactacttg caaacaggtg caacagttga
    12061 gcttggattt gacttgaaca aagcacactt cttcgatgta gaaactgaaa aaacaatcta
    12121 ctaaaataaa taaaattcaa agcactacaa gaaaagatat ctctttatca attgtagtgg
    12181 agagatatca gttaatctag ggagagaaac aaaatgcttc tctccttttt gctagggaag
    12241 tcatattatg catctatatt gtgatgctct ttaatactct tcgaaaatct cttcaaacca
    12301 cgtcaacgtc gccttgccgt acgtatgatt actgatttcg tcagttttat ctgcaacctc
    12361 aaagatgtac tttgagcagc ttacggctag tttcctagtt tgctctttga tttccattga
    12421 gtattatttg tgggtaccat ctacaagtga agctatatgc gtaaactacg tgagcaattg
    12481 aattcgaact agagaggtaa taataaattt atgctatagt tatggtgact tgtatgcttt
    12541 tgattctagt ttatcaaata atagattaga attgtcagat aatatcattt tgtgttataa
    12601 tgaagaaaaa acagaggtgt tcaaatgtca gaagcaggtc ataagttttt agcaaaattg
    12661 gggaaaaaac gcttacgtcc aggtggaaag cgtgccacag attggttaat tgcagaagga
    12721 ggattttcaa aagaaaagag aatactagag gttgcgtgta ataggggaac tacagcaatt
    12781 gagttggcac agcgttttgg ttgtaagata actgctgttg atatggatgc tcaagcttta
    12841 gaagtggcta aaaaatctgc tggaacggca ggtgttgctc atttaatcag ttttgaaaga
    12901 gcaaatgcaa tgaaacttcc ttatcaagat gctagttttg atattgttat aaatgaagct
    12961 atgctgacta tgcaagccga tcaagctaag aaaaaatgtg taatggaata tctaagggta
    13021 ttaaaacctg gaggtcttct attgacgcat gatgtgcttc ttaaggaagc taaagagtct
    13081 atcagacagg aattatcaca agcaattcat gtaaatgtag gtcctttaac tcaagatggt
    13141 tgggaacagg tgatgataga atcaggttat tgtgatgtga aagtattgac tggtgaaatg
    13201 acattaatga gattatcggg tatgatttat gacgaaggtt tgctaggaac tttgaaaatt
    13261 tgtgtaaatg cttgtaaaaa ggagaataga aagcagtttt taactatgta taaaatgttt
    13321 gctaagaata aacagaaatt gggctttatt gcgatggcta gttataaatc gtcaaaacgt
    13381 tagataatta ttgaagttaa cttttccttt tttctttctt aaaaaatatg ctataataga
    13441 gagtaaaaaa ctttgaaaga aagaaaaaga tgaatttaaa agattacatt gcaacaattg
    13501 aaaattatcc aaaggaaggc attaccttcc gtgatattag tcctttgatg gctgatggaa
    13561 atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag aaagtcgaca
    13621 tgatcgtggg acctgaagct cgtggattta tcgtgggttg tccagttgcc tttgagttgg
    13681 gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc acgcgaagtt atttctgctg
    13741 actatgaaaa agagtacggt gtcgatacct tgactatgca cgcggatgcc attaagccag
    13801 gtcaacgtgt tcttattgta gatgaccttt tggcgacagg tggaactgtt aaggcaacta
    13861 tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt gttgaattgg
    13921 atgaattgaa cggccgtgaa aaaattggtg actacgacta caaagttctt atgcattatt
    13981 aatgaaaaca gtccctaggg ctgttttctc tacactagga tataaaaata gactataact
    14041 agttagagaa aaactataat tgaaaactat atcttcttgc agtataataa aaggactaag
    14101 tgtttgagat ttgtcttcaa acatatgcaa ttattcctga aagagtacag ttaggagagg
    14161 gttatgccga ttcgaattga taaaaaattg ccagctgttg agattttacg gacagagaat
    14221 atctttgtca tggatgatca acgtgctgcc caccaagata tccgtccttt gaagatttta
    14281 attttaaatc tcatgccaca gaaaatggtc acagagaccc agttgttgcg ccacttggct
    14341 aatacacccc tacaactgga tattgatttt ctctatatgg agagccaccg ttctaaaaca
    14401 actcgttcag agcacatgga gaccttctat aaaacttttc ctgaagtcaa ggatgagtat
    14461 tttgatggga tgatcatcac gggtgctcca gttgagcatt taccatttga ggaagtggac
    14521 tattgggagg aatttagaca gatgcttgag tggtctaaga ctcatgtcta ttcgaccctt
    14581 catatctgtt ggggggctca ggctgggctt tatctgcgct atggtgtaga aaaataccag
    14641 atggacagta agctatcagg tatttatcct caggacaccc taaaagaggg tcaccttcta
    14701 tttagaggct ttgatgatag ctatgtatcc cctcattcac ggcacacgga gatttctaag
    14761 gaagaggtct taaacaagac caatctcgag attttatcag aaggacctca ggttggggtt
    14821 tctattttgg ccagtcgtga tttacgagaa atttatagtt ttggtcattt ggagtatgac
    14881 cgtgatacct tggcaaaaga gtattttcga gatcgtgatg caggtttcga cccacatatt
    14941 ccagaaaatt actttaaaga tgatgatgtt aatcaggtac cttgtctttg ttggtcttca
    15001 tctgcagccc tctttttcag taattgggta aaccatgcgg tctatcagga gacgcctttt
    15061 gactggagaa agatagaaga tgatgcatct gcatataggt atttataaga ggaattatga
    15121 catatttaga cgcttttaaa tcaggtacct tggttttacc gagtgccctg ctcttgcatt
    15181 ttaaggaact ctttccttct agcgacgatt ttctggtttg gcaatttttc tatttgcaaa
    15241 atacgacagg cttagaagaa atatcgccaa gccagattgc tgaaaggatt ggcaaggaaa
    15301 tttcggatgt caaccagtcc atttctaatc tgacggaaag gggactgctc cagtatcgta
    15361 ctatcgaatt aaatggcgaa attgaattgc tctttgatgc tagtttggcc ttggaacgtt
    15421 tggatgacct gtttggagca gttcattcaa gttcagacca gctaacacca caaaaccagc
    15481 tcaaggattt ggtggaaacc ttccagcagg agttgggacg attgttgacg ccttttgaga
    15541 ttgaggattt gaccaagaca ctaaaggaag atggaaccag tgctgacttg attaaggagg
    15601 ctcttcgtga agctgttttg aacggaaaac caaactggaa gtacattcag gcgattttga
    15661 gaaactggcg ccatgaagga atcaagagtg tggctcaaat tgaggccaag agagcagaaa
    15721 gagaagcaag caatcctcag ttgacacagg tatctgcaga tttcataaat gccatggatc
    15781 tctggaagga ttaatccatg caagtaggct tgaaatccga gtaagatttg caagctgtgt
    15841 ataattgtga tagaataaat agaaaataaa ttgaaaaaag aggtatgtga aatgtcacgt
    15901 aaaccattta tcgctggtaa ctggaaaatg aacaaaaatc cagaagaagc taaagcattc
    15961 gttgaagcag ttgtatcaaa acttccttca tcagatcttg ttgaagcagg tatcgctgct
    16021 ccagctcttg atttgacaac tgttcttgct gttgcaaaag gctcaaacct taaagttgct
    16081 gctcaaaact gctactttga aaatgcaggt gctttcactg gtgaaactag cccacaagtt
    16141 ttgaaagaaa tcggtactga ctacgttgtt atcggtcact cagaacgccg tgactacttc
    16201 catgaaactg acgaagatat caacaaaaaa gcaaaagcaa tctttgcgaa cggtatgctt
    16261 ccaatcatct gttgtggtga atcacttgaa acttacgaag ctggtaaagc tgctgaattc
    16321 gtaggtgctc aagtatctgc tgcattggct ggattgactg ctgaacaagt tgctgcctca
    16381 gttatcgctt atgagccaat ctgggctatc ggtactggta aatcagcttc acaagacgat
    16441 gcacaaaaaa tgtgtaaagt tgttcgtgac gttgtagctg ctgactttgg tcaagaagtc
    16501 gcagacaaag ttcgtgttca atacggtggt tctgttaaac ctgaaaatgt tgcttcatac
    16561 atggcttgcc cagacgttga cggtgccctt gtaggtggtg cgtcacttga agctgaaagc
    16621 ttcttggctt tgcttgactt tgtaaaataa tcagtaagta gcaaaagcta ggtggaacag
    16681 cattcagatg tctgttacat tttttatagg agaggaaaga ttgaaaataa aaattggatt
    16741 agcaagtatc tgtttactag gcttggcaac tagtcatgtc gctgcaaatg aaactgaagt
    16801 agcaaaaact tcgcaggata caacgacagc ttcaagtagt tcagagcaaa atcagtcttc
    16861 taataaaacg caaacgagcg cagaagtaca gactaatgct gctgcccact gggatgggga
    16921 ttattatgta aaggatgatg gttctaaagc tcaaagtgaa tggatttttg acaactacta
    16981 taaggcttgg ttttatatta attcagatgg tcgttactcg cagaatgaat ggcatggaaa
    17041 ttactacctg aaatcaggtg gatatatggc ccaaaacgag tggatctatg acagtaatta
    17101 caagagttgg ttttatctca agtcagatgg ggcttatgct catcaagaat ggcaattgat
    17161 tggaaataag tggtactact tcaagaagtg gggttacatg gctaaaagcc aatggcaagg
    17221 aagttatttc ttgaatggtc aaggagctat gatgcaaaat gaatggctct atgatccagc
    17281 ctattctgct tatttttatc taaaatccga tggaacttat gctaaccaag agtggcaaaa
    17341 agtgggcggc aaatggtact atttcaagaa gtggggctat atggctcgga atgagtggca
    17401 aggcaactac tatttgactg gaagtggtgc catggcgact gacgaagtga ttatggatgg
    17461 tactcgctat atctttgcgg cctctggtga gctcaaagaa aagaaagatt tgaatgtcgg
    17521 ctgggttcac agagatggta agcgctattt ctttaataat agagaagaac aagtgggaac
    17581 cgaacatgct aagaaagtca ttgatattag tgagcacaat ggtcgtatca atgattggaa
    17641 aaaggttatt gatgagaacg aggtggatgg tgtcattgtt cgtctaggtt atagcggtaa
    17701 agaagacaag gaattggcgc ataacattaa ggagttaaac cgtctgggaa ttccttatgg
    17761 tgtctatctc tatacctatg ctgaaaatga gaccgatgct gagaatgacg ctaaacagac
    17821 cattgaactt ataaagaaat acaatatgaa cctgtcttac cctatctatt atgatgttga
    17881 gaactgggaa tatgtaaata agagcaagag agctccaagt gatacagaca cttgggttaa
    17941 aatcatcaac aagtacatgg acacgatgaa gcaggcgggt tatcaaaatg tgtatgtcta
    18001 tagctatcgt agtttattac agacgcgttt aaaacaccca gatattttaa aacatgtaaa
    18061 ctgggtagcg gcctatacga atgctttaga atgggaaaac ccttattatt caggagaaaa
    18121 aggttggcaa tatacctctt ctgaatacat gaaaggaatc caagggcgcg tagatgtcag
    18181 cgtttggtat taagcgatga tttgaaagag ggatgtgata gtagcaccct ctttttcttt
    18241 gttttatgat agttcatcct cgagtaaatt caagatcttg ctcggaaatg aagcttatat
    18301 agtagattga atatagacaa ataccttgtg attggtaaaa cattttagaa attcatttac
    18361 ctttcctaat cgacttggtt tcatcttatt tcaatctatt atagtattgg ggaatttctt
    18421 caaaccacat cagcttggtc agttctacct gcgacctcaa aacttgtgct ttggtcaagc
    18481 tgggtttagt ttcctagttt gctgatggat ttccattgac tataagcatc caaccctctt
    18541 tttgtcttct aaagaattct taaattatca gtctattgca acttttctca tataagttct
    18601 ttgtcttgct attggttttc cttagtagta tactaaggta gtaatcatta agaagtggtt
    18661 acaaaaaata atgaatgagg taaagaaaat ggtagaattg aaaaaagaag cagtaaaaga
    18721 cgtaacatca ttgacaaaag cagcgccagt agcattggca aaaacaaagg aagtcttgaa
    18781 ccaagctgtt gctgatttgt atgtagctca cgttgctttg caccaagtgc actggtatat
    18841 gcatggtcgt ggtttccttg tatggcatcc aaaaatggat gagtacatgg aagctcttga
    18901 cggtcaattg gatgaaatca gcgaacgctt gattacactc ggtggaagcc cattctctac
    18961 attgacagag ttccttcaaa atagtgaaat cgaagaagaa gctggtgaat accgtaatgt
    19021 tgaagaaagc ttggaacgtg ttcttgttat ctaccgttac ttgtcagaac ttttccaaaa
    19081 aggtttggat gtcactgatg aagaaggtga cgatgtgaca aacggtatct ttgcaggcgc
    19141 taaaactgaa acagataaaa caatttggat gcttgcagcc gaacttggac aagcacctgg
    19201 tttgtaagaa ataaggaaac atagataaat ctgtaggaaa tttcttacag attttttcta
    19261 ttttgtaagc tattccaaac cagtcttttt ttgagttttt tgataaaata gtactatcag
    19321 tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt tgggcccagg atgaagaggg
    19381 tgtgattggt aaggacaatc gtctgccttg gcatttgcca gcagaattgc agcactttaa
    19441 agaaacaact ctgaatcatg ctatcttgat ggggcgtgtg acctttgatg ggatggggcg
    19501 tcgcttgctt ccaaaacggg aaaccctgat tttgacgcgt aatccggaag aaaagataga
    19561 tggggttgct acttttcagg acgtccagtc tgttcttgac tggtatcagg ctcaagaaaa
    19621 gaatctctac attatcggtg ggaagcaaat ttttcaggct tttgaacctt accttgatga
    19681 agtgattgtc actcacattc atgctcgggt ggaaggagat acctatttcc ctgaagaact
    19741 tgacttgtct ctttttgaga cagtttcaag caaattttac gccaaagatg agaagaatcc
    19801 ttatgatttt accatccaat accgcaagag aaaggaagtc taatggaacg gagtttattt
    19861 ggtctattca cggcttttct gtgtttcatc tgctttctgg caggagcaca ggcttttcgt
    19921 aaaaagcgtt acgggctttc tatcctcctt tggttaaatg cctttaccaa tctggtcaat
    19981 agtattcatg ctttttacat gaccttattt tagatagaat gacagtatag aatggaagga
    20041 aatcatgtct acaaatagaa aaaatgatat gatggtttat tgctcatttt gtggcaaaaa
    20101 ccaagaagaa gtacaaaaaa taattgctgg caacaatgct tttatttgta atgaatgcgt
    20161 ggagttagct caggaaatca ttcgagaaga attggttgag gaagtcttgg cagacttgtc
    20221 tgaggtgcca aaaccaattg aactcctcca tatcttgaac cactatgtaa ttggtcaaga
    20281 tcgtgccaag cgtgccttgg cagtggcggt ttataaccac tacaaacgca tcaatttcca
    20341 cgatacacgc gaagagtcag aagatgtgga tttgcagaag tcaaacattt tgatgattgg
    20401 cccaactggt tcagggaaaa ctttccttgc ccagaccttg gctaagagct tgaatgtacc
    20461 ttttgctatt gcggatgcga cagctctgac ggaggctggt tatgtgggtg aggatgtgga
    20521 aaatatactc ctcaaactct tgcaggttgc tgactttaac atcgaacgtg cagagcgtgg
    20581 cattatctat gtggatgaaa ttgacaagat tgccaagaag aatgagaatg tgtctatcac
    20641 acgtgatgtt tctggtgaag gggtgcaaca agcccttctc aagattatcg agggaactgt
    20701 tgctagcgta ccgcctcaag gtggacgcaa acatccacaa caagagatga ttcaagtgga
    20761 tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat ggtattgaag aaattgtcaa
    20821 acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaac aataaggcga ttgacgaaaa
    20881 cagctcatac atgcaagaaa tcatcgctga agacattcaa aaatttggta ttatccctga
    20941 gttgattgga cgcttgcctg tttttgcggc tcttgagcaa ttgaccgttg atgacttggt
    21001 tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa taccaaacct tgctttctta
    21061 tgatgatgtt gagttggaat ttgacgacga agcccttcaa gagattgcta ataaagcaat
    21121 cgaacggaag acaggggcgc gtggacttcg ctccatcatc gaagaaacca tgctagatgt
    21181 tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt cgcatcacta aagaaactgt
    21241 cgatggaacg gataaaccga tcctagaaac agcctagagg tgactatgga acttaataca
    21301 cacaatgctg aaatcttgct cagtgcagct aataagtccc actatccgca ggatgaactg
    21361 ccagagattg ccctagcagg gcgttcaaat gttggtaaat ccagctttat caacactatg
    21421 ttgaaccgta agaatctcgc tcgtacatca ggaaaacctg gtaaaaccca gctcctgaac
    21481 ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc ctggttatgg ctatgctcgt
    21541 gtttctaaaa aggaacgtga aaagtggggg tgcatgattg aggagtactt aacgactcgg
    21601 gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc atgacccgtc agcagatgat
    21661 gtgcagatgt acgaatttct caagtattat gagattccag tcatcattgt ggcgaccaag
    21721 gcggacaaga ttcctcgtgg taaatggaac aagcatgaat cagcaatcaa aaagaaatta
    21781 aactttgacc caagtgacga tttcatcctc ttttcatctg tcagcaaggc agggatggat
    21841 gaggcttggg atgcaatctt agaaaaattg tgaggaaaag aaaatggcaa aaacaattca
    21901 tacagataag gccccaaagg ctatcgggcc ctatgttcaa ggaaaaatcg ttggcaacct
    21961 tttgtttgct agcggtcaag ttcccctatc ccctgaaact ggggaaattg taggagagaa
    22021 tatccaagaa cagacagagc aagtcttgaa aaacatcggt gctattttgg cagaagcagg
    22081 aacagacttt gaccatgttg tcaaaacaac ttgtttcttg agcgatatga acgactttgt
    22141 tccttttaat gaggtttacc aaacggcctt caaagaggaa ttcccagctc gttcagctgt
    22201 ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt gaagtcatcg cagagattgg
    22261 ataagctagt tgaagtttgg tgttgccaaa cttcttttga tataaggaga aaaagatgac
    22321 aaagaaacaa cttcacttgg tgattgtgac agggatgagt ggcgcaggga aaactgtagc
    22381 cattcagtcc ttcgaggatc taggttattt caccattgat aatatgccgc cagctctctt
    22441 gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat cctaagttgg ccttggtagt
    22501 ggatatgcgt agccgttctt tcttttcaga gattcaagct gttttggatg agttggaaaa
    22561 tcaagatggt ttggatttca aaatcctctt tttggatgcg gctgataagg aattggtcgc
    22621 tcgttacaag gaaaccagac ggagtcaccc actagcagca gacggtcgta ttttagatgg
    22681 aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat atgagccaaa atgtggtgga
    22741 tacgactgaa ctcactccac gtgagctgcg caaaaccctt gcagagcagt tttcagacca
    22801 agaacaagcc cagtctttcc gtatcgaagt catgtctttc ggatttaagt atggaatccc
    22861 gattgatgcg gacttggtct ttgatgtccg tttcttgcca aatccctatt atttaccaga
    22921 actgagaaac caaacgggtg tggatgaacc tgtttatgat tatgtcatga accatcctga
    22981 gtcagaagac ttttatcaac atttattggc cttgattgag ccgattctgc caagttacca
    23041 aaaggaaggt aagtccgttt tgaccattgc catgggatgt acgggtggac aacaccgtag
    23101 tgtggcattt gctaaacgct tggtgcagga cttatccaag aattggtctg ttaatgaagg
    23161 gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt tcatgagaaa accaaagata
    23221 acggtgattg gtggagggac tggaattccc gtcattctaa aaagtctgcg ggaaaaagat
    23281 gtggaaatcg cagctatcgt gacggtggca gatgatggtg gttcttcagg tgaactccga
    23341 aaaaatatgc aacagttgac accgccaggt gatcttcgta atgtccttgt ggccatgtcg
    23401 gatatgccta agttttatga gaaggtcttt cagtatcggt tctctgagga tgccggagcc
    23461 tttgctggcc atccattggg aaatctcatc attgctggct tgtcagaaat gcagggttca
    23521 acctataatg ccatgcagtt attgagcaaa tttttccata caacagggaa aatttatcct
    23581 tccagtgacc atcctttgac ccttcatgca gtctttcagg atgggacaga agtggctgga
    23641 gagagtcata ttgtagacca tcgaggcata attgacaatg tctatgtgac caatgcccta
    23701 aacgatgata cgcctctggc cagccgtcga gtagtgcagg ccatccttga aagtgacatg
    23761 attgtcctag ggccaggttc cctctttacc tctattttgc ccaatatcgt gattaaggaa
    23821 attgggcggg ctcttttgga aactaaggca gaaattgcct atgtctgtaa tatcatgacc
    23881 caacgtgggg agacggaaca ctttacagat agcgaccacg tggaagtctt gcatcgtcac
    23941 cttggtcgcc cttttatcga cactgtcttg gtgaatattg aaaaagtgcc tcaggaatac
    24001 atgaattcca accgttttga tgaatactta gtgcaagtgg aacacgattt tgtaggtctt
    24061 tgtaagcaag tttcgcgcgt gatttcatct aacttccttc gtctggaaaa tggcggtgcc
    24121 ttccacgatg gagatttgat tgtggacgag ttgatgcgca ttatacaggt gaaaaaatga
    24181 gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca ccatctgagc tggcatgaat
    24241 tatctgccat tatcaaaatg tctggtagca tcggtctctc gacttcgggc ttgactttgt
    24301 cagttgtgac agaaaatgcc aaactggccc gtcacctcta tgagtccttt cttcatttct
    24361 atgaaatcaa atctgaaatt cgtcaccacc aacgtagcaa tcttcgcaag aatcgcgtct
    24421 ataccgtttt tacagatgaa aaggtgcagg atttgttaag tgatttgcac ttggcagact
    24481 ctttctttgg cctggaaaca ggtattgatg aggcgatttt atcggatgag gaagcaggtc
    24541 gtgcctatct ctgtggcgct ttcttggcaa atgggagcat tcgtgaccct gagtcaggca
    24601 agtaccagtt ggaaatcagt tctgtttatc tggaccacgc gcaaggaatt gcctcccttc
    24661 tccaacagtt tttactggat gccaaggtgc ttgagcgcaa gaagggggct gtgacctatc
    24721 tccagcgagc agaagacatt atggacttct tgatagtaat cggagccatg caggcacgtg
    24781 atgattttga gcgggttaag attttgcgag aaacccgtaa cgacctcaat cgggctaata
    24841 atgccgagac agctaatatc gctcggacag tttctgccag catgaagacc attaacaata
    24901 tcagtaaaat caaagatatc atgggcttag aaaatttgcc agtagatttg caggaagtgg
    24961 cgcaactgag gattcagcac ccagactact ctatccagca gttagcagat agtctcagca
    25021 cccctctgac caaaagtggt gtcaatcaca gactcagaaa aatcaataag atagccgatg
    25081 aattataaaa ccacgaatcc tatgtgactc gtggttcttt tttataaact ggtagagtgt
    25141 tttggttgta ctttttgttc agggtcaatg tagttgatag cgttgttgac agcagttgga
    25201 gcttctccga ggcctgtcgc aatcagatca atttttccgt catagtagca gcagtcaccg
    25261 atagcataga tacctgcttg gctggattct tgtttgctgt tgacgataat cttgtgacgg
    25321 ttgaggtcga gcccccagtt tttaaggtta ccgacagaag atttgaaacc atagttgaca
    25381 aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt tgacttttgt gatttcaagt
    25441 ttatcaagtg tttttccatt tccaaggagt tggccagggg cgaatggtgt cttgatggtt
    25501 acagatgatt cttgcaaggc ttgaacactg tgttccaagg cacggaaatt atctctgcgg
    25561 tgaacaaggg tagttggtgc gattttttca aaagccaaag cccaatccac agccgagtct
    25621 cccccaccaa gaatcgtcac tttcttacca gcgtattgct gaatgttaga aacgtggtag
    25681 tggatatttt catagccctc aaccccttca agttccagcg gacgtggttt gaaggcaccg
    25741 ccacccatag cgatgataac tgttttagtc aggtgacttc ctttagaagt tgtgatggca
    25801 aattcttctt gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat
    25861 ccatttagct gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct
    25921 ggtacgtcta ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga
    25981 agagagtcga tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc
    26041 ccgacaggac caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg
    26101 ttttttctag tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg
    26161 gaaaaaaatg cccgaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag
    26221 ggatgaattt tcaacaatta tccaatctgc aatattggac cagtttgttt gcaagtccat
    26281 ggacgatagc tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta
    26341 caaaagctat tgcaggaacc aagattatga ttttggtacg tggagttttg gtatttattt
    26401 tagctcaaat ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa
    26461 ttattactta tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt
    26521 tggaacgttt gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac
    26581 agatgattcg tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct
    26641 tggttgctat tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg
    26701 atgctaagat ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg
    26761 acggtgcggt gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga
    26821 caaaaaacac agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat
    26881 cagaagtctc agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa
    26941 cctataatgg aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg
    27001 aaatcttact tccaaaagag gaagtgggtc ttagttttaa agaacgattg ctaggaggat
    27061 ggaaacatga aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta
    27121 tttgtctatg ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg
    27181 gaaacctata ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag
    27241 tattttatta gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta
    27301 tcgctagcta gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca
    27361 gatgccggtg ttggaacgat tgaagttcct ttgagcattg aagatttacc caatgggctg
    27421 accgctgtgg cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat
    27481 aaggtaaaga ttgtaccaga gattgaccct agtcaaattg atagtcgggt gcaaattgaa
    27541 aatgtcatgg tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga
    27601 attgataaga ttatcgctgt cttgccaact agcgaacgta taacaggtaa ttacagtggt
    27661 tcagtacctt tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg
    27721 tttgatacaa taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat
    27781 tcaagtacaa gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg
    27841 aattaaaaat agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc
    27901 gtggagaagc taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag
    27961 gctatgttct tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac
    28021 gtatttcagg ggaaatgctg gaatcggcct tggtggcagg tctcctttca gtagggattc
    28081 acgtatacaa acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag
    28141 gagcaagtgc cggtgtcatg atttctgcta gccacaaccc agcccttgat aacggaatca
    28201 agttctttgg cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct
    28261 tgctagatgc tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg
    28321 tagattatcc agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc
    28381 ttgatggaat gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc
    28441 aaatctttgc agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta
    28501 acatcaacct taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa
    28561 gtgggtcagc tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg
    28621 agaatggtga catcgtcgat ggtgacaaga ttatgtatat catcggaaaa tacctttctg
    28681 aaaaaggaca attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc
    28741 acaaggcctt gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg
    28801 ttgttgaaga aatgagaaaa tcaggctaca accttggtgg tgaacagtct ggtcacgtta
    28861 tcttgatgga ttacaatacc acaggtgatg gtcaattatc agcagttcaa ttgactaaaa
    28921 tcatgaagga aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac
    28981 aaaaattagt taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag
    29041 ctatcaagac catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg
    29101 ttcgtccaag tggaacagag cccctcttgc gtgttatggc agaagcgcct acaatagaag
    29161 aagtggacta ctatgttgat accatcacag atgtagttcg tgctgaaatt gggattgact
    29221 aaatcctaga aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag
    29281 ccgatggaga aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt
    29341 gatgcgcgta attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg
    29401 aatttccaat tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcatcttg
    29461 agctttatga ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat
    29521 atcgatggcc gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg
    29581 gctcgtccat gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta
    29641 gacttaccag gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc
    29701 tgcttatctc agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt
    29761 caatattgat ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca
    29821 aaaaatggct caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga
    29881 tgagatctta acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc
    29941 ttctggaatt tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt
    30001 aaccattgct ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag
    30061 cgtctttaat tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat
    30121 tcaaatcagc cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg
    30181 tggacgcctt tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct
    30241 ttattttaac gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc
    30301 caccaaacgc ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat
    30361 tgtcattcat gggaatgctc ctgaaaaggc tgaagaattg cgtcagcatt tgcttgattt
    30421 tggcttgggt tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg
    30481 agcaggaagt attgctctgg gttatattcc agtgatttag taggcacttc taggctagtt
    30541 aatcttagca attgaacacg gactacctgc ctcttgaaaa aagatgtctg tcttgccttt
    30601 cgtggaaagt cagtgccatt ccctattttt catgggtggc taagatcctt tgtattttga
    30661 taattgaaca cgcctggaac cctgtgtgaa aaagatagtt cttccaagga gtagacactt
    30721 cttgatcaga attcctattt tcactttgtg ttcttacagg ctttgtatct tagacaggag
    30781 tagagatgag tattcgagta attattgccg gttttaaggg aaagatgggt caagctgctt
    30841 gccagatggt cttgcctgat tcagatttgg acttggtagc agttttggat ccttttgagt
    30901 ctgagtcaga atggcagggt attcctgttt tcaaggataa ggctgattta gctggttttg
    30961 aagcggatgt ctgggtagac tttactactc cagctgttgc ctacgaaaat acacgttttg
    31021 ctcttgaaaa tggctttgct ccagtagttg gaacgactgg tttcacgagt gaagaaattg
    31081 cagagctaaa agaattttct cgtgcccaag acttgggtgg cctgattgcc cctaactttg
    31141 ccttgggtgc tgtcttactc atgcaatttg cgacgcaggc tgccaaatat ttcccaaatg
    31201 tggagattat tgagctccat catgacaaga aaaaggatgc tccgagtgga acagccatta
    31261 aaacagctga gttgatggca gaggttcgag agtcaattca gcaaggtgca gcagatgagg
    31321 aagagctgat tgctggtgct cgtggtgctg actttgatgg tatgcgcatc cactcagttc
    31381 gtttgccagg cttggtagct catcaggaag tcatctttgg caatcaggga gaagggttga
    31441 ccctccgtca tgactcctat gatcgcatct ccttcatgac aggagtcaat ttgggaatta
    31501 aagaagttgt caagcgtcat gagcttgtct atggattaga acacttatta tgagattaac
    31561 gcaaatgcct tctgaatttc agaaggcttt accagtatta gaaaaaatta aagaagcagg
    31621 ctttgaggct tattttgttg ggggctctgt tcgagatgcc cttctccata gccctatcca
    31681 cgatgtggat attgcgacgt cttcttatcc agaagagacc aagcagattt ttccgcgaac
    31741 agccgatatc ggaatcgagc atggaaccgt cttggtctta gatggggatg aggagtatga
    31801 ggtaacaacc tttcggacag aggatgtcta tgtggactat cgcagaccca gtgcggtttc
    31861 ctttgtgcgc tcgctagaag aagacctcaa acgccgtgat ttcacagtca acgcctttgc
    31921 cttggatgag acaggagaaa tcgttgactt gttccatggt ttagaagatt tggaaaagca
    31981 agtcttgcga gcagttggag tggctagtga gcgtttcaac gaagatgctt tacggattat
    32041 gcgtggtttc cgttttcagg ctagtcttgg ttttgcactt gagccagaaa catttaaagc
    32101 tatgaagacc ttgacgccgc ttttggagaa aatttctgta gagcgtacct tcgtcgaatt
    32161 tgataaactc ttgctggctc cattttggag aaggggcttg gcttccatga ttgagagtca
    32221 agcttatgac tatctccctg atatggcatc tagccaggac aagctcaaca gactgtttga
    32281 tttggagact gattttactt ttgaatcctc tgaacaagcc tgggcggctt tactatgggc
    32341 tttggagatt gaaaatgcgc agtcattttt gaaatcttgg aagacctcac gccagtttgc
    32401 caagcaagtt caggatttgc tgattatttt ggctctgcgt gaaaatggag aattgagcaa
    32461 gcgagattgt tatcgctttg acatagattt gcttttacag gctgaaaatc ttcgtcaagc
    32521 tcaaggaaaa gaagtcaacc cacaagccat cacagaaaaa taccaaagct tgactatcca
    32581 tgacaagaaa gagattcaga ttaatggcga tattttgatc aaggaatatg gctatcagcc
    32641 aggcccagac ttgggagaga ttttaacaga gattgagttt gccattgtcg atggagaatt
    32701 ggagaataat cgtgaagcca tccatgctta cctgagggag aaaaaatgag tgattttatc
    32761 gttgaaaaac taagtaaatc cgttggtgac aagaccgttt ttagggatat ttcctttatt
    32821 atccatgact tagacagaat tggtttaatc ggtgtcaatg ggactggcaa gaccaccctt
    32881 ttggacgtcc tttctggtgt ttctggattt gatggggatg tcagtccttt ttcagctaaa
    32941 aatgattacc agattggtta tttgactcag gatcctgatt ttgatgatag aaagacagtt
    33001 ttggatacgg ttctatctag tgaactcaag gaaatccagc tcattcgtga gtatgaattg
    33061 attatgctcg actatagtga ggacaagcag gcgcgtttgg aacgtgtcat ggcagagatg
    33121 gactctctcc aagcttggga aatcgagagt caggtcaaga ccgttcttag caaattgggc
    33181 attcaagact tatctactcc tgttggggaa ttgtcaggtg gtctgagaag acgggtacag
    33241 ttggcacaag tcttacttgg caaccacgac cttttgcttt tggatgagcc gaccaaccat
    33301 ctggatattg cgattattga gtggctgacc ctctttttga aaaattctaa gaagaccgtc
    33361 ctttttatca ctcacgatcg ttatttctta gacgctttgt caacacggat tttcgagttg
    33421 gagcgagcag gcttgacaga atatcagggc aattaccagg actatgttcg ccttaaggca
    33481 gaacaggacg agcgcgatgc agctctactt cataaaaaag aacaactcta caaacaagaa
    33541 ctggcctgga tgagcagaca accgcaggcg cgtgcgacca agcaacaagc tcgtatcaat
    33601 cgtttccatg atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga cttgactatg
    33661 aactttgaaa ccagtcggat tgggaagaaa gtcatcgagt ttcaggctgt ttcctttgcc
    33721 tatgaaaata agcccatttt gcaagatttt aatctcttag ttcaggttaa agaccgtatt
    33781 ggaattgttg gggacaatgg tgttggaaaa tcaaccctac ttaacctgat tgcaggaagt
    33841 cttgagccga cagcaggaca agttgtgatt ggggaaactg ttcgcatcgc ctatttctct
    33901 caacaaattg agggtttgga tgaaagcaag cgtgtgatca attacctgca ggaagtggca
    33961 gaggaggtca agaccagtgg tggttctacg acttccatcg ctgagttgct ggagcaattc
    34021 ctcttcccac gttcgacgca tgggaccttg attgagaagt tgtcaggggg tgagaaaaaa
    34081 cgtctttatc tcctcaaact gcttttggaa aaaccaaatg ttcttctttt agacgagcca
    34141 accaatgacc tagatattgc aactttgaca gtcttagaga atttcttgca aggttttgca
    34201 ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc gaccaagatt
    34261 ctcgcttttg aggatggcaa gattcgtcct ttctttggtc attacaccga ctatcttgat
    34321 gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa ggaaaaagtg
    34381 gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga gtgggcaagt
    34441 attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga ggaaatgcag
    34501 gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga tgagaaaaat
    34561 gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga tagttaagac
    34621 tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa gtacagcctg
    34681 tgaccggctt cctaatttgc actttgattt ttattgagta taaaagaata gaaaaatccc
    34741 gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata ttttgccagg
    34801 tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag cagatgagtt
    34861 tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt aactcttttt
    34921 tggtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag acaaaatcat
    34981 cagtcaagag ttcttctagt tggtttcctt ggtcaatcaa ttgttcacgc ataagcaatt
    35041 ttttatagac attgtctaaa atttcatcct cagggatagg tgctggttcg atatggacat
    35101 cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc gcgatttcat
    35161 ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg tagatgttgc
    35221 taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt tccatgatag
    35281 ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta aaggaagact
    35341 cgatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata gcaaccagtt
    35401 tatccacaat cggataattg aaactactag ctaggatggc aatggcggtt ccaagtgagg
    35461 taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag ttggatttct
    35521 tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa atgattccta
    35581 gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt tgaatggtat
    35641 ctcttagaac atcgaaaccg acatagaaca tgatgataga agtgatcaag cttgccaaat
    35701 cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc gccatccgaa
    35761 tcccgattaa gagggccaca tttccaatga tgtccgatac gttattaaaa ccatcggcca
    35821 ccaaactgga tgaatgaagg agatgaccag ctgctaattt ggctgcagac aagatcaaat
    35881 aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag atagattgct
    35941 tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt tcaaggaaaa
    36001 attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat aatggtacta
    36061 ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt ttatgctgaa
    36121 aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac aggtctcttt
    36181 ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa tgtcaaggag
    36241 gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc ctgaagaggt
    36301 cttgcaggct gtggatgcga ccgagcaagg tttgtcatca agtgaggcgg aaaagcgcct
    36361 tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct tggtcaaatt
    36421 catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa tcttgtcagt
    36481 cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg tggttatcat
    36541 caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctattg aagccctcaa
    36601 atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag agattgactc
    36661 taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg taccagcgga
    36721 cctacgtttg atagaagcca actctcttaa aattgaagaa gcagccttga caggtgaatc
    36781 tgtaccagtc gaaaaagact tgtcagtcga gcttgcgaca gatgctggta ttggtgaccg
    36841 tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg gtgttgttgt
    36901 caatacaggt atgtacactg aagttggtca tattgctggt atgcttcaag atgcggatga
    36961 gactgataca ccactcaaac aaaatttgaa caacctttct aaggtcttga cctatgctat
    37021 cttggtcatt gcccttgtta cttttgtagt gggtgtcttc attcaaggga aaaatccact
    37081 tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag gacttcctgc
    37141 tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac attccatcgt
    37201 tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt ctgataagac
    37261 tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg cggttctaca
    37321 tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt cagttatctt
    37381 ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa ccgaaacagc
    37441 ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag agaaatatcc
    37501 tcgtgtagct gaattgccat ttgactctga ccgtaagctc atgtcaacag ttcacccatt
    37561 gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct taaaacgttg
    37621 tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta caaatctcat
    37681 tcatacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag gtgcttataa
    37741 gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg atttaatttt
    37801 tactggtttg attgggatga ttgatcctga acgtcctgaa gctgctgagg ctgttcgtgt
    37861 ggctaaggaa gctggaattc gtccaattat gattacaggt gaccaccaag acaccgcaga
    37921 agctattgcc aaacgtttgg gaatcattga cgcaaacgat acagaagacc acgttttaac
    37981 tggtgctgag ctcaacgaat tatctgatga agactttgaa aaagttgttg gtcaatactc
    38041 tgtttatgcc cgtgtgtctc cagagcacaa ggttcgtatc gtcaaggctt ggcaaaaaca
    38101 aggtaaggtc gttgccatga caggtgacgg tgtcaatgat gccccagctc tgaaaacagc
    38161 agacatcggt atcggtatgg gaatcactgg tacagaggtt tctaaggggg cttctgatat
    38221 gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag gacgtaaggt
    38281 cttctcaaat attcaaaaga ctattcagta cctactttct gccaatactg ctgaagtatt
    38341 aaccatcttc ctatcaacct tgtttggttg ggacgtcttg cagccagttc atcttttgtg
    38401 gattaacttg gtaacggata ccttcccagc aattgcacta ggtgttgaac ctgcggaacc
    38461 tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag gtggtgtttt
    38521 gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg tttatggcct
    38581 tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag atgccctaac
    38641 gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg tcaagtctgt
    38701 ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact ggtccatctt
    38761 ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag gaatcttcca
    38821 cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct tctcaatgat
    38881 tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca agaatgcgat
    38941 ttaagggagg tttcggatgt cagcatatca attaccgacc gtatggcagg atgaagctag
    39001 taatcaagga gcttttacgg ggttaaacag accaacagca ggtgcccgtt tcgaacaaaa
    39061 cttgccaaaa ggagaacaag cttttcagct ttattcactg ggaacaccaa atggtgtgaa
    39121 ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg cttacgactt
    39181 gtataagatt gctatcatgg atggggatca attcggctca gactttgtga agctcaatcc
    39241 aaattccaag attccagcct tattggacca gtcaggtact gaaaacgtaa gagtctttga
    39301 gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac caagtaatcc
    39361 tgtggaaaag gtagaagttt tgaattggct attctggcaa gcaggtgcag caccttttct
    39421 aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat atcctattaa
    39481 ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat tggctcagaa
    39541 accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt cttggtatgg
    39601 acagttagtt caaggaaatc tttaccaagg ttctgcaaaa tttttggatg cctcaagtta
    39661 tcaaaatcta gtaaaatggg cagaaaaaat tgccaatcgt ccagctgtta agcgtggatt
    39721 ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg ctttttgcta
    39781 cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta taatatagta
    39841 aaaagcaaga ggagtgtgag gaagtggaaa agaaaattgt gaaggatatc ttatttttat
    39901 ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat ttgcaggata
    39961 cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt ggggtgcaga
    40021 agcgcgtgat tatctttaat cttggcttgg ttcccgtggt catgtttaac ccagtgcttc
    40081 tgtcctttga aggatcttat gaggcagaag aaggctgttt gtccttggta ggtgtgagat
    40141 caactaagcg ttatgaaacc ataaggcttg cctatcgtga cagcaagtgg caggaacaga
    40201 ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat cacttggaag
    40261 gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta tttttatcgc
    40321 aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat ttctcttctt
    40381 cctctgtggg catttgttag ttgtggcaat cttatttggc tttggcaagg ggataaacct
    40441 tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc ttgagggttt
    40501 caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc ttctcttggc
    40561 agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg ccaatgtagt
    40621 cacggttacg gaaaaagact ttactgaatt tcctaggagt gacaccagta aggttcctat
    40681 cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc taaccgataa
    40741 ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg ggaaacctta
    40801 tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc aagccaaggg
    40861 aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg tggacttgaa
    40921 gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac gtcacctgcg
    40981 cttgaagtac ccgactaaaa tctttaaaac tccatctttt gaggtggacg atgagggcaa
    41041 tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgcggttc ctcgtcctgc
    41101 ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct tatcagatgt
    41161 tccagaatgg gtggacaggg tctatccagc agaggaaacc attgagcaaa tcaactacaa
    41221 cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaatg tgacccagac
    41281 taccaagggc tataattact tgtctatcgg taatgacatc tatctctaca caggtgtgac
    41341 gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc gaacaggaga
    41401 aatcactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat cagcagaagg
    41461 tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc tcaatgacaa
    41521 gcctctctac atcatgggct taaaggacaa tgctggcttg gtcaaagagt acgccctggt
    41581 agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga tgctcagcaa
    41641 gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca tcaagggagt
    41701 agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct ttaaagttga
    41761 tggcaagata tacaaggtca aggcttcagt atccgatgac cttccttacc ttgaaaatgg
    41821 taaaaccttc gaaggtcaag taggaaaaga caattatctc aagaccttta aagtacaata
    41881 atactcttcg aaaatctcta gctctatctg caacctcaaa acagtgtttt gagcagcctg
    41941 cggctagttt cctagtttgc tctttgattt tcattgagta taaaaaaggt ttatttaata
    42001 aatatatgtt ataataaggt aaattaagcc taatggagga caaagaaatg ggtttttatt
    42061 tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt tctcagttca
    42121 aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca gcccttgttc
    42181 tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca aaccgaggtt
    42241 tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat atgaaaattt
    42301 taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca attcctttaa
    42361 aaccagaaag tcagaccgtg cttgatgcct tggctctcta ttctgccagt caattggaga
    42421 gtttctacaa ggtatcggct gagaaagcgg cggaagaatt tcaaaatatc caagctttga
    42481 aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt atgtaccgca
    42541 acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat catgtcttca
    42601 ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct caccgtttgg
    42661 attttttgat gaaattaaaa gtcgctggta agactttgaa gagccattgg aaggcagtct
    42721 atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca gagtttgaga
    42781 ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg gaggatagag
    42841 gcggtcagct gaagattcac tcaactatct ccaagaaagc gcgcggggcc tttctaacag
    42901 ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac tttgctggat
    42961 ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag gaagtataga
    43021 aatcagatat tttgtatttg gcaatatgta tcatcagctg ttttagttta taaatgagaa
    43081 aaaaagcgaa caagctagtc ttctgagtgt cagaaaagta gtcttgttcg cttttattat
    43141 gttatactct tcgaaaatct cttcaagcca cgtcagcgtc gccttaccgt atatatgtca
    43201 ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagcagct tgcggctagc
    43261 ttcctagttt gctttttgat ttttattgag tgttagttac ttgatagctt cgaccaagtc
    43321 ttgagcttgt ttttcaagtg agtttaggac tgtttcttca agaaccaatt ttccgtctgc
    43381 ccaggcagag tcattaacac gtgcagcagt gaaatcacca acgccttgtg tacggataaa
    43441 tggcaagagg tctttgtaga tagcgaaaag ttgatcgtgc cctgcattgg ctacagatga
    43501 tactgtgaca aacttgtctt gaagggcaga aacgccacgt gtatcagaca agtcaagggc
    43561 acgagatagc cagtcaagca agtttttcac tgtaccaggg atagagaagt tgtagactgg
    43621 agagaaaatc cagatagcat ccgcaacgag aactgcttca cgagcagcag ctacagctgg
    43681 atgtgttgga acttccaaat cttggctgaa gagaggaagg gctgaataat caaggtagct
    43741 aacttccgct ttaccagcaa gagctttctc agcttcgagc gccatttggt ggttgaaaga
    43801 accttgacgt agtgatccga cgataaataa tactttttta gacatgatgt gtctcctttt
    43861 tcttaaaatt tcgagaactc tctcgttgtt ataaaatata ttacaacaaa acaaaagaac
    43921 ttgcaagaaa tttgctcaga gtttatttga aaattgtaaa atttcggaaa ctctagtcat
    43981 ttgtgactga aaaagtaaga actgtttcac tttcaaaatc ggttttgttt gaagggagaa
    44041 atagaattgg ttgctcaaag cacagctttg aggttgcaga taaagctgac gtggtttgaa
    44101 gagattttcg aagagtattc ttatattcac ttgtaataaa gcttaataga tggtaaaata
    44161 gacgagtgaa aaaaagacaa aacaaagcaa aaaataatct actgtggcag tatggtctag
    44221 ggatgacgat tttgtttgtg gttatcagtg cttcctttct gtatatggtt tctcttagca
    44281 tgaaacccta tcaaacagct aaaagtgaag gagaaaaatt agctcagcag tatgcaggat
    44341 tagagaaggc tgatcaggtt gatttataca atggcttgga atcttattac agcgttcttg
    44401 gtcgtaataa acagcaagaa gcgcttgctg tcctgattgg taaagatgac cataagattt
    44461 acgtttatca gctaaatcag ggtatttcac aagaaaaagc agaaacggtt tctaaggaaa
    44521 agggagctgg cgagattgac aagataacct ttggtcgtta tcaagacaag ccaatctggg
    44581 aagttaagtc aggatctgat ttttatctag tagattttga aacaggagca ttggtcaata
    44641 aggagggcct atgaaactat ccaaccgtgt tttagaaatg gaagaaagtg tgactttggc
    44701 tgctggagcc cgtgccaaag cactgaaggc tgagggtaga gatattttgt ctctaacctt
    44761 gggtgagcca gatttcacta ctcccaaaaa tatccaagat gccgccattg catcgattcg
    44821 agatgggcgt gcttcttttt atacagtaac ctcaggtctg ccagagctta aggcggtggt
    44881 caatagctac tttgagcgct tttacggcta ttctgtagcg tcaaatcaag tgacagtcgc
    44941 tgcgggagcc aaatattctc tctatacctt ctttatggct gtggtcaatc caggtgatga
    45001 agtcatcatc ccaaccccat actgggttag ctatggagat caggtcaaga tggcagaagg
    45061 cgttcccgtc tttgtttctg ctaaggaaga caatcacttt aaggtgaccg tagagcagtt
    45121 agaagcagct cgcactgaca agaccaaggt tttggtgctg aattcgccat ctaatcccac
    45181 aggtatgatt tacacccgtg aggaactctt ggcaattgga aactgggctg tagaaaatga
    45241 tattctcatc ctagcagatg atatctatgg ccgcttggtt tataatggtc atgagttcac
    45301 accgatttct agcctatcgg aagcgattcg caagcaaaca gtggtcatca atggtgtgtc
    45361 taaaacctat gccatgactg gttggcggat tggttatgcc gttggagaag cagacattat
    45421 cgctgccatg tccaagattg caggtcaaac aacttcgaat ccgtcagcag tagcccaata
    45481 tgcagcagtt gaggctctat caggtgagca agatactgta gaaagcatgc gtcaggcctt
    45541 tgaggaacgt cttaatacca tctatcccct ccttgcagag gtgccaggat ttgaagtggt
    45601 caaaccacaa ggggccttct atctcttccc aaatgtcaaa aaggccatgg agatgaaagg
    45661 ctacacggat gtgacagact ttacaactgc tatcttagaa gaagccgaag tggccttggt
    45721 aacaggagct ggatttggag caccagaaaa tgtccgcctc agctatgcga cagacctaga
    45781 cacgcttaaa gaagcagtcg aacgcttgaa agcatttatg ggtagtgaga atgattgatc
    45841 attttgagat taaggtaaag gatttacaaa tttcagaagg attttatagg agttttctcg
    45901 ctcctttgga ctataaattg gcttttaaga ctagttctct aattagtttt ctatccccga
    45961 acagccctca tcctggtggt gatttttggc tgactcaggg aacacaagat cctgttcatt
    46021 ttgctttttt agcagaaaat aaggaagaag ttcaggcttg ttatgaggct ggcttagagg
    46081 caggtgggcg agacaatggg gttcctggtt atcgaagtga gcatccgatt tattatgctg
    46141 cttttatgat tgacctggat gggaacaata tagaggtggt ttgccataaa gaataaaaaa
    46201 gaaaaggaaa aataatgaca aaacgtgtaa cgattattga tgtaaaagac tatgttggtc
    46261 aggaagtgac gattggcgct tgggttgcca acaaatcagg aaaagggaaa atcgctttct
    46321 tacaattgcg tgatggaaca gccttctttc aaggtgtggc ttttaaacca aactttgtcg
    46381 aaaaatttgg tgaagaagtg ggacttgaga agtttgatgt tatcaaacgc ttgagccaag
    46441 aaacgtctgt ttatgtgaca ggtattgtca aagaggacga acgttctaaa tttggctatg
    46501 agttggacat cacagacatc gaagtgatcg gtgaatctca agactaccca atcacaccaa
    46561 aagaacacgg aacagacttt ttgatggata accgtcactt gtggctacgc tctcgtaagc
    46621 aagtagctgt gttgcaaatc cgtaacgcta ttatctatgc aacttatgag ttctttgaca
    46681 agaatggttt tatgaagttt gacagcccaa ttctttcagg aaatgcggca gaagattcta
    46741 cagaactctt tgaaactgac tacttcggaa cgccagccta cttgagccaa tcaggtcagc
    46801 tttacctaga agcaggggct atggctcttg gtcgtgtctt tgactttggt ccagttttcc
    46861 gtgctgaaaa atcaaaaaca cgccgtcact tgactgagtt ctggatgatg gatgctgagt
    46921 actcatactt gacacatgat gagtcgcttg acttgcaaga agcttatgtg aaagctcttc
    46981 tacaaggtgt tcttgaccgc gcgcctcaag ccttggaaac cttggaacgt gatacagaac
    47041 tcttgaaacg ctacattgca gagccattca aacgtatcac ttacgatcaa gccattgacc
    47101 tcttgcaaga gcatgaaaat gatgaagatg ctgactacga gcatcttgag catggtgatg
    47161 actttgggtc accacacgaa acttggattt caaaccactt tggtgtgcca acatttgtca
    47221 tgaactatcc agcagccatc aaggccttct acatgaaacc agttcctgga aatccagagc
    47281 gcgtgctttg tgcagacttg cttgctccag aaggctatgg agaaattatc ggtgggtcta
    47341 tgcgtgagga agattacgat gcccttgtcg ctaagatgga tgaacttggc atggatcgta
    47401 cagaatatga attctacctt gaccttcgta aatacggtac agttccacac ggaggatttg
    47461 gtatcggtat cgaacgtatg gtaaccttcg cagcaggaac aaaacatatc cgtgaagcta
    47521 ttccattccc acgtatgttg caccgtatca aaccataaga acaggaaaac gcccatgtgg
    47581 cgttttttcg aattctagtg tttttacttg cgtaaaaaaa ttttttctag tataatagtt
    47641 tattgtgagc gaacctcact taccccttgc aaagtcttgg ggtcattaga ccaaaaggag
    47701 gaacatatca atggctaaat acgaaattct ttatatcatt cgtccaaaca ttgaagaaga
    47761 agctaaaaac gctttggtag cacgttttga ctctattttg actgacaacg gtgcaactgt
    47821 tgttgaatca aaaacttggg aaaaacgtcg tcttgcatac gaaatccaag atttccgtga
    47881 aggactttac cacatcgtta acgttgaagc aaatgacgat gcagctctta aagagtttga
    47941 ccgtctttca aaaatcaatg ctgacattct tcgtcacatg atcgtcaaaa ttgacgcgta
    48001 agaaggtaaa ctatgattaa caatgttgta cttgtagggc gtatgacacg tgacgctgag
    48061 ttgcgttata ccccatcaaa tgtagcagtt gcgactttta ctcttgcagt aaaccgtaca
    48121 tttaagagtc aaaatggtga acgtgaggct gattttatca atgtcgttat gtggcgccaa
    48181 caggctgaaa atcttgctaa ctgggctaaa aaaggctcac ttatcggggt gacaggtcgt
    48241 atccagactc gtagttacga taaccagcaa ggacaacgtg tctacgtgac agaggtcgtg
    48301 gctgagaatt tccaaatgtt ggaaagccgt agtgtgcgtg agggtcacac aggtggagct
    48361 tactctgcac caactgcaaa ctattcagca cctacaaatt cagtaccaga cttttcacgt
    48421 aatgaaaatc catttggagc aacaaaccca ttggatattt cagatgatga tttaccattc
    48481 taatggacaa ctaaacttat aaaggagaaa aaacatggct caacaacgtc gtggcggatt
    48541 caaacgccgt aaaaaagttg attacatcgc agcaaacaaa attgaatatg ttgattacaa
    48601 agatactgag cttcttagcc gtttcgtttc agaacgtggg aaaatccttc ctcgtcgtgt
    48661 aacaggaact tcagctaaaa accaacgtaa agtaacaaca gctatcaaac gcgctcgcgt
    48721 aatggctttg atgcctttcg taaacgaaga ttaaagaaaa gacccggttg ggtctctttt
    48781 tcatgagctt gaaaacaaga aagcgaatta agaccccaac gggtcttttt tcacaagctt
    48841 tgaaatgaga gagcgagtta ggctcagtgg ctcccttttt acgagtttga aaacaagaga
    48901 acacattaaa agcacgatgg agctttttca taaatatgtc tcttttctca tccaagaaat
    48961 taaaataaaa atgataaact ttttgaaaat aggggatttg cctactttat gatataatgg
    49021 aaagagttag attgaaagag gtagtgagat ggacgcgaaa ttaagataca aggcaaagaa
    49081 gatcaagatt gtcttttttg atattgatga tacattgcgg aattcaaaga cagggtttat
    49141 tccaactaca attcccactg tttttaaaca gttgcgtgaa aaaggaattt taataggaat
    49201 cgcctctgga cgtggcattt ttggtgttgt tccagagatt cgtgatctca agcctgactt
    49261 ttttgtaact ttgaatggag cttatatcga agataaaaaa ggtcaggtca tttatcagca
    49321 tcagattgaa aagtcagatg ttgaggagta tatctcttgg gctaagcaag aaggaattga
    49381 gtatggcttg gttgggagtc atgatgccaa gttgtcgact cgcaccgata tgatgagtga
    49441 agctatcaat ccaatttatc ccgacttaga tgtagatccc gatttccatg aaaaagaaga
    49501 tatctatcag atgtggactt ttgaagataa gggagatgac ttgcacttgc ctgacagtct
    49561 ctcagacaaa cttcgcatgg ttcgttggca tcaacattcg tctgatattg tgccgatttc
    49621 aggctccaaa gcgacggggg tggaaaaggt tgtggaacac cttggcttga aaccagagaa
    49681 ggtcatggtt tttggagatg gtctcaatga cttggaactc tttgattatg ctggaatcag
    49741 cgttgccatg ggaatttctc atgataaaat caaagaaaaa gcggattata ttacaaaaac
    49801 attagaagaa gatggcattt ttgatgcctt agaagtattt ggtatggtag aaaaagaatt
    49861 gcattttcca caagtagaca ttgaaacagt agaaggtcct cttgcgacta ttaagaccaa
    49921 tcacggagac ttacgtatca agcttttccc tgaacatgct cctaaaacag tggctaactt
    49981 tgtatctctt tcaaaagatg gctactatga tggtgtcatt ttccaccgta ttatcaagga
    50041 ctttatgatc caaggtggag acccaactgg aactggtatg ggtggcgagt caatctacgg
    50101 cgaatctttt gaggatgaat tctcagaaga gctttacaat atccgtggtg ctctttccat
    50161 ggcaaatgct ggtccaaata ccaacggcag ccagttcttt atcgtgcaaa accaacacct
    50221 accttattcg aagaaagaaa ttactcgtgg tggttggcca gaaccgattg cagaaatcta
    50281 tgccaatcaa ggtgggacac ctcacctaga ccgccgtcac acggtttttg gtcagttagc
    50341 tgatgaagca tcttacgctg tcttggatgc cattgctgct gttgagacag gagctatgga
    50401 caagccagtt gaagatgttg taattgaaac tattgaaatc gaggactaag atgaaaatcg
    50461 gtgataagct aaaggggcgt attacaggga ttcagcccta cggtgccttt gttgagttag
    50521 agacgggtga tacggggctg attcacattt cagaaattcg gacaggattt attgaaaata
    50581 ttcatgaaac cttgaaagtc gatgaagagg ttcaagttca ggtagtggat ttagatgaat
    50641 ttacggggaa agccagtctt tctatccgca ctttggagga agaaaagtac cagtttccta
    50701 gacggagacg cttttcaagc gaccgcttta actacggttt tgctcccttt cgacgaatgt
    50761 taccaatctg gactggagaa gccctgcacc atttaaaaaa gaagaagtag tttagagttt
    50821 tatatttttt gtaatgttaa tataaatttg ctataatagg accatggaag aagaacaatt
    50881 attaaaatca ggagagcgca ttaaccagct cttttcgaca gatatcaaaa tcattcaaaa
    50941 tagagaggtt tttagctatt cggtggatag tgttctctta tcacgatttc cacgttttcc
    51001 taagaagggg ttgattgtgg atttctgtgc tgggaatgga gcagtggggc tttttgctag
    51061 cactcgtact caagcacaga tattgtctgt tgagattcag gagcgtttgg cggatatggc
    51121 tgaacgctct gtccgtttga atggattaga ggagcaaatg caggtcatct gcgatgattt
    51181 gaaaaatatg cctgctcaca ttcaggggag taaggtggat atgattttgt gtaatccacc
    51241 ctatttcaag gtggatcctt attctaatct gaacgagagt gaacattatc tcttggctcg
    51301 acacgaaatc acgactaatt tggaagaaat ctgtcgtagt gctcagagta ttctcaagtc
    51361 taatgggcgt ttggccatgg ttcatcgtcc tgatcgactt ctggatattt tggatacgtt
    51421 aaaacgacat aatctagccc ctaagcgcct gcagtttgtt tatccaaaaa gagaaaagga
    51481 agccaatatg cttttgattg aggcgatcaa ggatggctca acaagtggct ttaaggtctt
    51541 acctcctttg attgtccaca atgatgatgg ctcttatacg cccgaaatcg aagagattta
    51601 ttatggatca taaggcttat atgtacgttc tggagtgtcg tgatggatcc tactatatag
    51661 gctatacgac tgatgtgaga agacgcctcg ctatccacaa tagtgggagg ggagccaaat
    51721 atacacgagc acgcttgcca gtcaaactta tctatgctca aggttttgcc agtaaggaag
    51781 aagccatgtc ggctgaagct cttctcaagc gtaagaagag gccacagaag gaagaatttt
    51841 tatctgaaaa tcaagataga aatttactca gttattttga agaatcgtgg ggagtccttt
    51901 gactcctctt acctttgtca aaaagcgaaa aaaatgctac aataaagaaa ataaacaaaa
    51961 tgaggtatta tcatgtccaa gattctagta tttggtcacc aaaatccaga ctcagatgcc
    52021 atcgggtcat ctgtagcttt tgcctacctt gcaaaagaag cttacggttt ggatacggaa
    52081 gctgttgccc ttggaactcc aaatgaagaa acagcctttg tcttgaacta ttttggtgtg
    52141 gaagcaccac gtgttatcac ttctgccaaa gcagaggggg cagagcaagt tatcttgact
    52201 gaccacaatg aattccaaca atctgtatca gatatcgctg aagtagaagt ttacggtgtt
    52261 gtagaccacc accgtgtggc taactttgaa actgcaagcc cactttacat gcgtttggag
    52321 ccagttggat cagcgtcttc aatcgtttac cgtatgttca aagaacatgg tgtagctgtg
    52381 cctaaagaga ttgcaggttt gatgctttca ggtttgattt cagataccct tcttttgaaa
    52441 tcaccaacaa cacacccaac agataaaatc attgctcctg aattggctga attggctggt
    52501 gtgaacttgg aagaatatgg tttggcaatg ttgaaagctg gtaccaactt ggctagcaaa
    52561 tctgctgaag aattgattga catcgatgct aaaacttttg aactcaacgg aaataatgtc
    52621 cgtgttgccc aagtgaacac agttgacatc gctgaagttt tggaacgcca agcagaaatt
    52681 gaagctgcaa tgcaagctgc caacgaatca aacggctact ctgactttgt cttgatgatt
    52741 acagatatcg tcaactcaaa ctcagaaatc ttggctcttg gtgccaatat ggacaaggtc
    52801 gaagcggctt tcaacttcaa acttgaaaac aatcatgcct tccttgctgg tgccgtttca
    52861 cgtaagaaac aagtggtacc tcaattgact gaaagcttta atgcgtaaga ttttgggtgt
    52921 cagctcaaaa tcggaaagtc tagtttgcct tatatcgaaa ggagtttcgg ctcctttttt
    52981 ctaggagtga agtatgttag aaaatggcga tttgattttt gtgagagatg ggtcagacat
    53041 gggacaggcc atccagactt ccacaggtaa ctatagccat gttgccattt atttggatgg
    53101 gatgatttat catgctagtg gacaggctgg tgttgtctgt caagaaccgg cagacttctt
    53161 tgagtccaat catttatacg acctctatgt ttacccagaa atggatatcc agtcggtgaa
    53221 ggaaagagct tgcaaacatc ttggagcacc ctacaatgct tctttctatc cagatgcagc
    53281 tggtttctac tgctcccagt atatagcaga aatcctacct atttttgaaa ctattcctat
    53341 gaaatttgga gatggggagc aggagattag tgatttttgg agggagtatt acatagaact
    53401 aggtctgcct gttcctctga accaagctgg taccaatcct agtcagttgg cagcatcgcc
    53461 tctgttacaa tgtaaagaaa ggaatcttca tgattcagat ttttaatcca tctcgtttga
    53521 cgagacagcc atttttggag aattgatccg ctatctggac cagtatgagg atgtgattct
    53581 acgggaaatt aaggctcaat ttccagatgt tgcagttgat aaactcatgg aagagtatat
    53641 aaaggcaggc ttgattctac gtgaaaataa gcgctattac ctcaattttc ctacgcttga
    53701 atcacttgat agtcttgaac tggatcaaga gatttttgtc agagaagcta gtccggtcta
    53761 tcaagccttg ttggagcaga gttttgagac ggaattgcgc aatcaaatca atgcagctat
    53821 tttagttgaa aagacggact ttgcgcgcat taaaatgacc ctgtccaatt atttttacaa
    53881 ggtcaaacag cagtatcctt tgacagaaaa acagcaggag ctctatgaca ttttaggaga
    53941 tgttaatcct gagtatgccc tcaagtatat gacggctttt ttgttgaaat ttctcaaaaa
    54001 ataccagctt atgcagaaat gccgtgatat ctttgtggac agtttggttg tcttaggcta
    54061 tattgtgcaa aatgaagatg gaaagtatga gttggctatc gattttgata aggagagatt
    54121 aactttctac ttagcgtgat ttcttgtttc tgagcacatt gtttgacttt ccttagtatt
    54181 cggtataaac tatatgtaac cggtaacaca tatcggaata aactaaagga gacaatcata
    54241 tgtcacttga aaacaaattg gaacaagcaa caggcgctgt caaagaaggt tttggtaaag
    54301 ttactggaga cagcaagaca gaacttgaag gagctgttga aaaaacagtt gctaaggcaa
    54361 aagacgttgt agaagacgca aaaggtgctg tagaaggtgc cgttgaaggt ttgaaaaacg
    54421 tttttactaa agaataggaa aaaatcaagg gtttcatttt cccttgattt tttctattct
    54481 tataaataat tttctgcgac ggctgtatct cctgggtagg attctttctt gccctggatg
    54541 atttggtaac aatcggctcc cttacccgca ataataactg catctaattc gtgatttgtg
    54601 atagccattg ccgccttgat ggcttcttgg cgatccgcaa tcttttcaac aggatgattg
    54661 atgtagttac taatttcatc tgcaatggcc attgggtctt catagttagg gtcatcagca
    54721 gtcagaaaga cttgaatctc agggtgttga ttgaggagga ggccaaagtc cttacgacga
    54781 ctttctccct tgtttcctgt tgatcccaga accagagcaa tctttccggt ttgatgagtt
    54841 tcaaccacat tgatgagttt tttcagacta tccccattgt gggcatagtc gatgaagacc
    54901 ttggctccat ttttctgagt gaggacttcc atacgaccag gaacgcgggt tgcagcgatg
    54961 ccttttttga tgtcctcaag acttgctccg agacggagac aagcaagtcc agcagcaact
    55021 gcattttctt ggttgaagtt gccaatgagt tggatatcat aatctccagc gagtttaccc
    55081 gtagctgaaa agctaaaggc tttggaattc tcgatttggt tatcaaattg gctaccatag
    55141 aaatcatggt cttgatcttc aacctgttct ctcaagactg agaagtggtc catgtcactg
    55201 ttaatgatga ctgctcggct attttccatc aagagacgct tgtggtagaa atagtcttca
    55261 aagctagggt gttcaatcgg gccgatatgg tctgggctga tatttaggaa aactcccaca
    55321 tcaaaggtca gtccatagac tcgatggact agataggctt gactggagac ttccatgatg
    55381 aggtgagtac ggtcattttg cacagcctga ttcatcatgt caaagaggtc aatactctca
    55441 ggggttgtca acgctgactt aaagaaagtc tcgccatcaa gagttgtgtt catggtcgac
    55501 aacatagcag gtctatgccc ttgagataag atgttatagg cgaaataggt tgctgttgtc
    55561 ttacccttag taccagtaaa ggcaaggagt ttgagtttct cttgtggatt accatagaac
    55621 tccatggcaa tcaaactcat ggctttcttt atatcgttca caatgatgac agggatatcg
    55681 acttcgtagt ccttttcagc tacataccaa gctaaacctt gtgttatagc agaaagaagg
    55741 tattcttttt taaaggcagc gccttttgca aaaaaaagag tgtcttctgt tacttttcgg
    55801 ctgtcgtagc tgatgctatc aaaaataact ttgctgtagt tgtagtggta atgaccttgg
    55861 tcaataattt cgcgaaaaag gccatctttc tttaaaatat ctaatacggt ttcaatctta
    55921 atcatacttt ctattgtaaa ccgaaagtcg taaatttaca agtaacaagg aaaagtttat
    55981 aatggaagat aaggagtttt tcctagttat caaaattgaa tgaggaatct atgtcgcacg
    56041 aaaacaatca ccagcaggcc cagatgttac gggggactgc ttggctaacg gctagtaact
    56101 ttatcagtcg cctactcggg gctgtttaca ttatcccttg gtacatctgg atgggggctt
    56161 atgcagctaa ggcaaatggt ctctttacca tgggttacaa tatctatgct tggttcttgt
    56221 tggtttcaac agcggggatt ccagttgcgg tggccaagca agttgccaag tataatacca
    56281 tgcgagaaga agagcatagc tttgccctga ttcggagctt cttaggcttt atgacaggac
    56341 taggcctggt ttttgcttta gtcttgtatg tctttgctcc ttggctagca gacttgtctg
    56401 gcgtgggcaa agacttgatc ccaatcatgc aaagcttggc ttggggagtc ttgattttcc
    56461 cgtctatgag tgttatccga ggatttttcc aagggatgaa taacctcaaa ccctatgcca
    56521 tgagccaaat tgctgagcag gtcattcgtg ttatctggat gctcctagca acctttatca
    56581 ttatgaagct cggttcagga gattatctag cagccgttac ccaatcaacc tttgctgcct
    56641 ttgtcggtat ggtagccagt tttgcagtct tgatttattt ccttgcccaa gaaggttcac
    56701 tcaaaagagt ctttgaaaca ggagataaga ttaacagtaa gcgtctcttg gttgatacca
    56761 ttaaggaagc cattcctttt atcctgacag ggtctgccat ccagctcttc cagattttgg
    56821 atcagctgac ctttatcaat agtatgagct ggtttaccaa ctacagcaat gaggacttgg
    56881 ttgtcatgtt ttcttatttc tcagccaatc ctaataaaat cacgatgatt ttgatttctg
    56941 taggggtttc gattgggagt gttggtttgc cacttttgac ggaaaactat gtcaaggggg
    57001 acttgaaagc ggcttctcgt ctcgttcagg acagtctcac cctactcttt atgttcttgc
    57061 taccagcaac ggttggagtg gttatggtag gagaacctct ttatacggtc ttctatggta
    57121 agccagatag tttggctctg ggcttatttg tctttgcagt tttgcagtct attattttag
    57181 gcttgtacat ggtcttgtct ccaatgcttc aggccatgtt ccgcaaccgc aaggccgttc
    57241 tctattttat ctatggttct attgccaagc tagtcttgca actacctacc atcgccctct
    57301 tccacagtta tggtcctttg atttcaacaa ccattgctct catcattcct aacgtcttga
    57361 tgtatcggga tatttgtaaa gtaactggtg tcaagcgcaa ggtgattttg aagcgaacca
    57421 ttttaatcag tttgctgacc ctagtcatgt ttctgttaat aggaaccatc cagtggctgt
    57481 taggattttt cttccaacca agtggacgtt tgtggagctt cttttatgta gctcttgtcg
    57541 gtgccatggg gggtggactt tatatggtta tgagtctgcg tacctattta ttagataagg
    57601 taataggaaa agcccaagca gatcgcctgc gagcaaaatt taagctttcg taaggtagca
    57661 tttataaata aaaggaataa gttgaacaat cttttaggag aacttgaaac ttattccttt
    57721 tttagcgtca aaatagctaa aattatcttt caaaaataga aaatgaggtt tttttgattt
    57781 tttggaaaaa acaattgact aaacaaacca agagttgtat aataaaacaa atatttaaag
    57841 caggaggttc tggaaatgaa aaagtctaag agcaaatatc taaccttggc aggtcttgtc
    57901 ctgggtacag gagttttatt gagcgcgtgt ggaaattcta gcactgcatc aaaaacctat
    57961 aactatgttt attcaagtga tccatctagt ttgaactatc tagcagaaaa ccgcgcagca
    58021 acatccgata ttgttgcaaa tttggtagac gggttattag aaaatgacca atatgggaat
    58081 attattccat cattagcaga ggattggact gtttctcagg acggtttgac ctatacctac
    58141 aaacttcgta aggatgccaa gtggtttact tctgagggag aagaatatgc gcctgtaact
    58201 gcccaggatt ttgtgacagg tttgcaatat gcagctgata aaaaatcaga agctttgtat
    58261 ctagtgcagg actctgttgc tggtttggat gactatatca ctggtaaaac aagcgacttt
    58321 tcaactgtcg gtgtcaaggc acttgatgac caaacggttc aatatacttt ggttaaacca
    58381 gaactttact ggaattcaaa aacacttgca acgatacttt ttcctgttaa tgcagatttc
    58441 ctgaaatcaa aaggggatga ttttgggaag gcggatccat ctagtatttt gtacaatgga
    58501 cctttcttga tgaaagcact tgtctcaaaa tctgctattg aatataagaa aaaccctaat
    58561 tactgggatg ctaagaatgt ctttgtagac gatgtgaaat tgacctacta tgatggtagc
    58621 gaccaagaat cactggaacg taattttaca gctggtgctt atactacggc tcgtcttttt
    58681 cctaacagct ccagctatga agggattaaa gaaaaataca aaaacaatat catctatagt
    58741 atgcaaaatt caacttcata tttctttaat tttaacctag ataggaagtc ttacaattat
    58801 acttctaaaa caagtgacat tgaaaagaaa tcgacccagg aagcagttct caataaaaac
    58861 ttccgtcagg ctatcaattt tgcttttgac agaacatctt atggggctca gtctgaaggg
    58921 aaagaaggtg caacaaagat tttgcgtaac ctagtggttc ctccaaactt tgtcagtatc
    58981 aagggaaaag actttggtga agttgtagcc tctaagatgg tcaactatgg taaggaatgg
    59041 caaggtatca actttgcgga tggtcaagac ccttactaca atcctgagaa agccaaggct
    59101 aagtttgcgg aagctaagaa agaactcgaa gcaaagggtg ttcaattccc aatccacttg
    59161 gataagactg tggaagtaac agataaagta ggcatacaag gagttagttc tatcaaacaa
    59221 tcaattgaat ctgttttagg ttctgataat gtagtgattg acattcagca attaacatca
    59281 gatgagtttg acagttcagg ctactttgct caaacagctg ctcagaaaga ctatgattta
    59341 tatcatggcg gttggggacc tgattatcaa gacccgtcag cctatctcga tatttttaat
    59401 actaatagtg gaggagttct acaaaatctt ggactagagc ctggagaagc caatgacaag
    59461 gctaaggcag ttggactgga tgtctatact caaatgttgg aagaagctaa taaagagcaa
    59521 gatccagcca aacgttatga gaaatatgct gatattcaag cttggttgat tgatagttct
    59581 ttagttcttc caagtgtttc gcgtggggga acaccatcat tgagaagaac cgtaccattt
    59641 gctgctgcct atggtttaac cggtacaaaa ggggttgaat catataaata cctcaaagta
    59701 caagataaga ttgtcacaac agacgaatat gcaaaagcca gagaaaaatg gttgaaagaa
    59761 aaagaagaat ccaataaaaa agcccaagaa gaattggcaa aacatgtcaa ataaaatcta
    59821 attgtagata agtttgtgta agaagtcttt gtgcttaaaa acgcataata tcaggtatat
    59881 aaaatcctag atgttatgcg ttttgttata ggaagattta ttagatttta tcctcaaatt
    59941 gagttattcc cgactttatc cgttgaaata ttataaggag tatttatgaa attaaaatta
    60001 ttaagagtag atactaaggt gattatgggg agtttcttac ttgttctgtc tagtctactt
    60061 gctttgttgc ttccccttat cttaaagggt ttaatagatg ggagttctat tgaaaatata
    60121 ggttccaaag tatttcaatc gtattggtca agccttgttt tcttctattg gttactatct
    60181 gtttagtcaa tcgggtgaaa aaaagatagc aaaaatcagg aaaaaagtga tagaggggtt
    60241 gatttatgca gagaaatcct tctttgataa gagccaaagt ggggagttga cttctgccat
    60301 tgtcaatgac atgagtgtca ttcgtgagtt tttaattacg actttcccaa atattattct
    60361 gagtttagtt atggtacttg gttccattgt agtcttattt agtcttgatt ggaatctttc
    60421 tctactttta ttcatcactc ttccttgtat gatgtttatt atcttgcccc tttccaatat
    60481 cagtgaaaag tatagtcgtc gtttacagga ggaaatttaa cagggcaatt gactgaaaag
    60541 attcaagaac atgaattaat taagactaac caagcagaga aaagtgtaca ggatgttttg
    60601 gataattgta ttgaaagggt acaaaacaat tcactgaaat cagatagggt tacttctttt
    60661 gagaccccgt ttgctctctt atttatcttt gcgactatag ctgtgatgct aacctatggg
    60721 ggttatcggg tcagcgcagg atatatatct gtgggaacct tggtttcgtt tttgatttac
    60781 ctctttcaat tacttaatcc tattagtaat atagctaatt ttgtaactgt ttattctagg
    60841 agcaagggat cttcagttgc actggataac ttgcttgcag ttcctaaaga aaaatttgag
    60901 ggaggaaaat cggtatcagg acaagggttg aattttaacc atgtctattt tggttatgat
    60961 gaaaatcgac ctgtcttaaa ggatattact tgttcaattt tcaaggggca aaaattgctt
    61021 ttgttggacc atctggatca ggaaaatcaa cgattgtgcg tttgttagag cggttttata
    61081 aaccgctttc aggagatatt ctaatggagc aatcaagtat atatgatttt aacttaaaag
    61141 aatggagaag taaaatcgct tgggtttcac aaaataatgc agtcttatct ggcagtattc
    61201 gtgacaatct ttgtctcggt ttgaatcgct tagtaactga tgatgaattg atgaaagtgc
    61261 tagacttagt atcactaggt gatgagattc gctccatgaa agagggacta gatactgaag
    61321 ttggtgaacg cggacgattc ttgtcagggg ggcaaagcca aagacttcaa atagctagaa
    61381 cctacttaaa agatgctgaa attcttatat ttgatgaagc tactgctaat cttgatgcgg
    61441 attctgagta tgcgattatc agtagcctct attctgtatt aaaggagaag acggttgtga
    61501 ttatagcgca tagtttgtca acggtaaaag atgtggattg tattttcttc ttagaggagg
    61561 ggaaaatcac tggctcagga actcataagg aactactgga aaatcatgag cgttatgctt
    61621 gttttgtgca ggagcaaatg atagagtgaa gtgtcttttg agattcacca ttttatagtc
    61681 tattaaaggg agcaggaaaa actccctttt tatatagttt gaaactataa ctagctcttg
    61741 aaaagaagaa aatgagttga tgaaaataag tggtacaata gttactatag atttggaggt
    61801 attgtatgag caaggaatta cacattaaca caattttggc ccaggcgggt attaagtcag
    61861 atgaagcgac aggtgcattg gtgacaccgc ttcatttttc aacgacctat cagcatccag
    61921 agtttggtcg atctactggg tttgactata cgcgcactaa aaatccaact cgtagtaagg
    61981 ctgaggaagt cttggcgact attgagtcag cagactatgc cttagcgact agctcaggga
    62041 tgtcagctat tgtactggcc tttagcggct ttccagtagg aagtaaggtc ttggcagtgc
    62101 gtgatcttta cggcggttct tttcgctggt ttaaccaagt ggagcaggaa ggtcgtttcc
    62161 attttaccta tgccaataca gaagaagagt tgattgccga gttagaaaag gatgtggatg
    62221 ttctctatat cgaaacccca accaatccct tgatgttgga atttgatatc gaaaaactag
    62281 caaaattggc tcatgctaag ggtgccaaag tggtggtgga caataccttc tatagcccta
    62341 tctaccaacg tccgattgaa gatggagcag atatcgttct ccattcagca accaagtatc
    62401 tagcaggcca caatgatgtc ttggctggag tggttgtgac caatagttta gaactatacg
    62461 agaagctttt ttacaatctc aatacaacag gggcagtctt gtctccattt gacagctacc
    62521 agttgcttcg tggtctcaag accttgtctc ttcgtatgga gcgctcaaca gctaacgccc
    62581 aagaagtggt tgcctttttg aaggattctc cagcagttaa ggaagttctc tacactggtc
    62641 gtggaggcat gatttccttt aaagtagccg atgaaacacg cattcctcat attttgaaca
    62701 gtctcaaggt cttctctttt gcggaaagtt tgggcggagt ggaaagtctt attacttatc
    62761 caacgactca aactcatgct gatattccag cagaagtacg ccattcttat ggtttgacag
    62821 atgacctctt gcgtttgtct attgggattg aggatgctag agatttgatt gcagatttgc
    62881 gccaagcctt agaaggataa gacaaagatg ggaaaatatg attttacaag cctgcccaac
    62941 cgtttagggc accataccta taaatggaaa gaaacagaaa cggatagtga agttctacca
    63001 gcttggatag cggatatgga ctttgtggtc ttgcctgaaa tccgccaagc cgtgcaaatt
    63061 tacgcagacc aactggttta tggttatacc tatgccagtg aagacttaat taaggaagtt
    63121 caaaagtggg aagctacaca atacggttac aactttgaca aagaggctct tgtctttatc
    63181 gagggtgtgg taccagccat ctcaacagct attcaaacct ttacaaaaga aggcgaggcg
    63241 gttttaatta acacgcctgt ctacccaccc tttgctcgca gtgtcaagtt gaataatcgt
    63301 agattgatta ctaattcctt agtggaaaag gatggtctgt ttgagattga ctttgaccaa
    63361 cttgaaaagg atttggtgga agaggaggtt aaactctata ttctttgcaa ccctcacaat
    63421 cctggtggac gtgtttggga aaaagaagtg ttggagaaga ttggccaact ctgccaaaaa
    63481 cacggtgttt tgttagtttc ggatgagatt caccaagatt tgaccctctt tggtcacaaa
    63541 caccagtctt tcaataccat caatcctgcc ttcaaaaatt ttgctatcgt cttgagcagt
    63601 gccactaaaa catttaatat tgctggaaca aaaaattcct atgcagtcat tgaaaatcct
    63661 aagttgagac tagctttcca gaaacgcctg ttggccaata atcagcatga aatttcaggc
    63721 ttgggttatt tggcgacaga agctgcctat cgatacggta aagattggct agaggaactc
    63781 aagcaagtct ttgaagacca catcaattat gtggtggatc tatttggaaa agagactaaa
    63841 atcaaggtca tgaaaccgca aggtacctac ttgatttggc ttgacttttc agcttatgac
    63901 ctgactgatg aaacattgca agagttgttg agaaatgaag ccaaggttat cctcaaccgt
    63961 ggtttggatt ttggagagga aggaagtctc catgcccgca tcaatatagc tatgcccaaa
    64021 tctctgttgc aagaagtctg tcagcggatt gtggctactt ttgccaaacg ttaaaaatcc
    64081 agccttctag gagaaaagtc ttcctagaag gctattttca taggcgaaaa tatggtataa
    64141 taaaaagata aggtaaaggt gaaaatatgg ctaaattgat tccggggaaa attcgtatcg
    64201 aaggtgttgc cctttatgaa actggtaagg ttgatatcat caaggaaaag aacaatcggc
    64261 tctacgctcg cgttgcagaa gaagaactgc gctatagttt agaggatgat ttggtttttt
    64321 gtgcctgtga tttttttcaa aagaggggtt actgtgtgca tttggcagcg ctagagcatt
    64381 ttctgaaaaa tgatgagcgt ggtcaggaaa tcttgtggag tctggaagaa ggtcatgaag
    64441 aaaaagaggc tgttgaaacc aaggtaacct tgggtggcaa gtttttggat cgaattttat
    64501 ctccaaaatc agaatgcgcc tatgagttat cagctgtggg tcaggtggaa gcaggaacca
    64561 atcatatctt gtggactctg agaatcggcc aaatcaatag ccaaaaatac tatgtcattc
    64621 gggatattcc acttttttta aggattgtcg agcagagaaa gtcgtatatg attggcaaga
    64681 tttatgagga gtctctttct tgggaagcct ttgatgatgc cagccaagaa cttttgactt
    64741 tcttgcacgg actaacggag gaagggctgg tttcagacct ctttttccaa aaccaaggtc
    64801 ggcacctctt tttccctctg accttttttg agcagggtgt gaatttactg atggccttgc
    64861 cccattttca atttgaccat caagtggata gctaccaaac cctgcttttt caggatatgc
    64921 atgctgatgc caatctattt gcctttacag taacagaata ctcggactat tttgaaatgg
    64981 aaatcagtga gagtcctagg gtcaatgtct tttatcaggg agcagtactt ttccataaag
    65041 gtcaggttta ttttttaaca gaccagcaga tgcgtcttct caaggaaatt aaagcgttac
    65101 ctgtgggtca acaaggaaag aaatacctgc aatttgatag cagtgatcga gacaaattgg
    65161 cctcctgtct gactcttttt atccagatgg gcaccgtttc agctccagaa cgtctacaaa
    65221 tcaaaacttt tgcgccctct ttttactttg acagggaaga agataatcgg attcgtttag
    65281 aaattcagtt tgattatgga aatagacagg tatctagccg acaagagcta gaagaattac
    65341 cattttcaag tgacgcggac ttagaagaaa gaattttcca agtctgtttg gctgcgggct
    65401 ttgaagccga ttttcaatct tggcgtcagg ccttaaaagc ggagtctgtc tatcattttt
    65461 ttcatgatat cattccagtc tttgaaaaac tcgggcatgt tgacctatca gataaactag
    65521 aagagcttta tagcctagcg agtcctcagg tgcagattgc ctccaaggga ggtctcttgg
    65581 aaatccagtt tgattttcaa gatattgccc aggaggaaat cgaccaagcc atgcaggtct
    65641 tggttgccaa tcaggatttt tatattgatt cgtctaatca agtttacttt ttcgatgaag
    65701 aaaccaagaa aattcgccaa aatctacagg aactggggca atttgaatta aaagatggga
    65761 ccttgcaggc tcggaaatcc ttggcctaca gtttagctca tctctttgaa gggcgagacc
    65821 gtgtttcttt ttcacaagaa ttccagaatc tggcccagga tttgacacat ccagaggact
    65881 ttcctcgaca ggcaactcag gttcaggctg acttgcgaga ttatcaggaa aagggaattg
    65941 gctggttgca gatgctccat cattatggtt ttggtgggat tttggctgat gatatgggac
    66001 ttgggaaaac ccttcagacc attgcttttt tgactagtca agtgacaaaa gaaagtcggg
    66061 ttttgattct cgctccgtca ggtttgattt acaactgggc agatgagttt cagaaatttg
    66121 ccccacagtt ggatgtggct gttgttcatg gtttgaaagc aagtcgtgag gagattcttg
    66181 ccgagagcca tcaaatctat gtgactagct atgccacctt ccgtcaggac agtgagtttt
    66241 atcaggggat ggcctttgac ttccttttct tagatgaggc tcaggtcatg aaaaatgccc
    66301 agaccaagat tgcccagacc ttgagacaat ttgtggtgcc gtcggtcttt gccttgtcag
    66361 gaactccgat tgaaaaccat ctgggtgagt tgtggtctat tttccaaatc gtcatgcccg
    66421 gacttttgcc aagcaagaaa gaatttatga aattgccagc agagcgagtg gctcagttta
    66481 tcaagccttt cgtgatgcga cgcaagaaag aagaagttct gactgaattg ccagacttga
    66541 ttgaggtggt ttataaaaat gaactggaag accagcaaaa ggctatttac cttgcccagt
    66601 tacaacagat gcgagaccat ctggctcaag tgtcagaaca ggaatttcag cgaagtcgtg
    66661 tggaaatttt atctggtttg atgcgcttgc gtcaaatatg tgacactcct gccctgttta
    66721 tggaagatta tcagggagcc agcggcaaac tagatagtct ccgagaccta ctggtacagg
    66781 tggcagacgg cggacaccgt gtcttgattt tctctcagtt caagggaatg ttggaaaaaa
    66841 ttgaacaaga actgccagac ttgggcctga catcctttaa aattacgggt tcaaccccag
    66901 ccaaggaaag acaagacatg accaaggcct ttaaccaagg agaaagagat gcctttctga
    66961 tttccctcaa ggctggtggg gtcggtctga acctgacagg tgcagataca gtgatcttgg
    67021 ttgacctttg gtggaatcct gcggtggaag cgcaagccat tggccgtgcc catcggatgg
    67081 gtcaggaaga aacggttgag gtctatcgct tggtgaccaa gggaaccatt gaagaaaaaa
    67141 ttcaggaact ccaagaacaa aagaaacatc tggtgtcaca agtattggat ggcacagagt
    67201 cacgtggtag tctgacccta gcagaaatta gagaaatttt gggaatttct gaagccagca
    67261 cttgaaaaat caagacaata cgctataatg aagtgttgaa aggaaataga aaatgaaaca
    67321 agaacgattt ccattggtgt cagatgacga ggtcatgttg actgaaatgc cagtcatgaa
    67381 tctctatgat gagtctgatc tgatcagtaa tatcaagggt gagtatcgag ataaaaatta
    67441 tttagaatgg gctcctatta ctgaagaaaa accagtaaaa ccgattgaaa agcaagtcga
    67501 aaaacctaaa aaggctcctt taggggttaa aaaagaagga aagagctatg cggaggtggc
    67561 gcgtgaagaa gcgcgtgcgg acttgaaaaa gaaacgctct gctaactacc taactcagga
    67621 tttcagcctt gcgagacgtc attctcagcc cagtctagtt agacagggca atcaaccgac
    67681 aactcctttc caaaaggaaa atcctggtga atttgtcaaa tatagccaaa aattgaccca
    67741 gtctcattat atcttggcgg aagaagttca ttctatccct accaagaatg aagaagtgtc
    67801 agcacctgct ccaaagaaaa acaattatga ttttctaaag aagagccaaa tctacaataa
    67861 aaaaagtaaa caaacagaac aagaacgtcg ggttgcccaa gagttgaatc tgaccagaat
    67921 gacagaatag gggagaaaac atgtcaaaga catatcattt tatcggaatt aagggatcag
    67981 ggatgagtgc cttggccttg atgttgcacc agatggggca caaggttcag ggatcagatg
    68041 ttgaaaagta ctactttacc caacgcggtc ttgagcaggc aggaattacc attcttcctt
    68101 ttgatgaaaa gaatctagac ggtgatatgg aaattatcgc tggaaatgcc tttcgtccag
    68161 ataacaacgt cgaaattgcc tatgcggacc aaaatggtat cagctacaaa cgttaccatg
    68221 agtttctagg tagctttatg cgtgactttg ttagcatggg agtagcagga gcacatggaa
    68281 aaacttcaac gacaggtatg ttgtctcatg tcttgtctca cattacagat accagcttct
    68341 tgattggaga tgggacaggt cgtggttcgg ctaatgccaa atattttgtc tttgaatctg
    68401 acgaatatga gcgtcacttc atgccttacc acccagaata ctctattatc accaacattg
    68461 actttgacca tccagattat ttcacaagtc tcgaggatgt tttcaatgcc tttaacgact
    68521 atgccaaaca aattaccaag ggtctttttg tctatggtga agatgctgaa ttgcgtaaga
    68581 ttacgtctga tgcaccaatt tattattatg gttttgaagc tgaaggcaat gactttgtag
    68641 ctagtgatct tcttcgttca acaactggtt caaccttcac cgttcatttc cgtggacaaa
    68701 acttggggca attccacatt ccaacctttg gtcgtcacaa tatcatgaat gcgacagccg
    68761 ttattggtct tctttacaca gcaggatttg atttgaactt ggtgcgtgag cacttgaaaa
    68821 catttgccgg tgttaaacgt cgtttcactg agaaaattgt caatgataca gtgattattg
    68881 atgactttgc ccatcatcca acagaaatta ttgcgacctt ggatgcggct cgtcagaaat
    68941 acccaagcaa ggaaattgta gcagtctttc aaccgcatac ctttacaaga accattgccc
    69001 tgttggacga ctttgcccat gctttaaacc aagcagatgc tgtttatcta gcgcaaattt
    69061 atggctcggc tcgtgaagta gatcatggtg acgttaaggt agaagaccta gcaaataaaa
    69121 tcaacaaaaa acaccaagtg attactgttg aaaatgtttc tccactccta gaccatgaca
    69181 atgctgttta cgtctttatg ggagcaggag acatccaaac ctatgaatac tcatttgagc
    69241 gtctcttatc taacttgaca agcaatgttc aataggatgt tcccatggaa attccaatta
    69301 agatcattca ggcaagcaag tctgatttgc ctgagatagg ggcacttcag acctcgtctt
    69361 ttccagctga aaagcagcaa ctttcccata ttttagaaga aagtatccgt aagtgtgcgg
    69421 atacctttct tctagctagg gatgaaaatc aacttttagg ctatatttta tcaagtcccc
    69481 agtcagacaa tccgcaatgt ctaaaagtac attctttagt catcgagtct gaccatcaga
    69541 gacagggcct gggaacactt cttcttgcag ccttgaaaga ggtggcagtt gagctggatt
    69601 gcaaagggat tcgtttggag agtcctgatg agctgctttc ctattttgaa atgaacggtt
    69661 ttgttgatga agaagaaact ttgctctatg caactagcca gggctatagt atgatttggt
    69721 ttaatccctt ttatctggag gaacaatgaa aatcagacaa gcaagattag aagatttgga
    69781 tcggattgtt gaacttgaat ttgaaaattt ttcggtcgaa gaagccattc ctccttctgt
    69841 ctttgaagca catttgagag aaattcagac ctcttttctg gttgctgaaa aagaaggaag
    69901 aatcatgggt tatatcgaag gaccagttgg cctgcaccgc catctgcaag accagtcttt
    69961 tacagaagaa ataaaagact atagtcatga gcctggtggt tatatctctg tgacctgtct
    70021 gtctattgcc aaggaggcac agggactcgg actgggtcag aaattgctga cagccttgaa
    70081 agaagttgct cttgaagatg agagagatgg cattaatcta acctgtcatg actatctcat
    70141 cgcctactat gaaaaacatg gatttgtcaa cgaaggccag tcccagtcaa cctttgcagg
    70201 ggaaacatgg tatgatatgg tctgggaaat gaaaaaataa gttaggaaaa gtatcataga
    70261 ttgctttttt tggactttta agatataata ttatggatta tcaacaagga ggaaaaactt
    70321 ttgagtgaaa agtcaagaga agaagagaaa ttaagcttta aagagcagat tctgagagat
    70381 ttagaaaaag taaaaggcta tgatgaagtt ctgaaagaag atgaggcagt agttcgcact
    70441 cctgcaaatg aaccttcagc tgaagaactc atggctgatt ccttgtcaac ggtagaggag
    70501 attatgagaa aagctcctac cgtgcctact cacccaagtc aaggtgtacc agcttctcca
    70561 gcagatgaga ttcaaagaga aactcctggt gttccaagtc atccaagtca agatgtacct
    70621 tcttctccag cggaagaaag tggatcaaga ccaggtccag gtcctgttag acctaagaaa
    70681 cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac gacggcagag
    70741 aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac agtggatatc
    70801 atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa acctaagaaa
    70861 gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct tgccttgctc
    70921 tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc tatcgatgct
    70981 aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca agaaatcggt
    71041 acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt ttatgccaag
    71101 tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag tatgagtaca
    71161 gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga acctgtactt
    71221 gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaaac tgtgggtcaa
    71281 ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa agttcaagat
    71341 gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag tttgcctgta
    71401 aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac atactctatc
    71461 aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat ggataagaac
    71521 ctatctcctt actatagtac tatcaaatct aaaaacttga ctatcaatga gttgttgacc
    71581 attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct cattgcaggt
    71641 gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc aatcttgtat
    71701 gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat tgataccgac
    71761 attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc agtcgatagt
    71821 ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa cctctacttt
    71881 gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga ccacgaccgc
    71941 aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta tgtgatactt
    72001 cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg cagaaaaaac
    72061 atatcctatg acccttgagg aaaaggagaa acttgaaaaa gaattagaag aattgaaatt
    72121 ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg gtgatctttc
    72181 agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag gacaaatctc
    72241 tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag ttgcccagga
    72301 cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg aagaagaagt
    72361 ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt caaatgaaag
    72421 cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca ttgaaacgcc
    72481 tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa aacagaaaaa
    72541 ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt cttcgaaaat
    72601 ctcttcaaac cacgtcagcg tcgccttgcc gtatatatgg ttactgactt tgtcagtttc
    72661 atctacaacc tcaaaaccat gttttgagct gacttcgtca gtttcatcta caacctcaaa
    72721 acggtgtttt gagcagcctg cgcctagttt cctagtttgc tctttgattt ttattgagta
    72781 ttagatgtat agtgcattga agttaaaata gtacactttg atttctaaga cattgttaga
    72841 aattagatta aattccttaa tcgatttgcg catgttttat ttcatttcat tatactttag
    72901 attggaaaat aaggaatcac ataaatcgca agaaataggg aatctgattc gtgtttataa
    72961 ccgttcaaaa agagaagagg ctgaaagtga gccacttaat ctttatgtcg aagatgaaaa
    73021 gggcaatctc cttgcgggtt tgatagcaga gacttttgga aattggctag aaatcgagta
    73081 tttgtttgta aaagaggaac tgcgagggca aggaatcggt tcaaaactat tgcaacaggc
    73141 agaaagtgaa gctaagaatc gaaattgttg ttttgccttt gtcaatactt accagttcca
    73201 ggcaccggac ttttatcaga aacatggcta caaggaagtt ttttctttgc aagactatct
    73261 ctacattagg caaagatatt attatcaaaa gaatctgtaa ggtgagtatg gaggtggact
    73321 gatatatatg agtaactatc gataaatacc agttataacc tagaaattgt gtctttctag
    73381 acgatattga ggacaatata atcgtagccc caaaattagg aatcaaggct tatcaggtta
    73441 agaaaagaag tgatgttgtt gatattttaa aacaatttat ttaaactaaa aactctctat
    73501 ctttttaaat tgacattaat ccgagattcc cctctcggat tttgtgttgc tttcattaaa
    73561 tttacaggta agacttgcta gcttcagtaa atatacacaa gtttttcaga atagagtgaa
    73621 atccaaaaga aaatggaaat aatgaaagct cttgtaggca taagaaaaca cctttgtgtt
    73681 atacttgttg ttcaaccaca aacacaagaa aggcacagag atgcaaaacc attatactac
    73741 aaaaggcgaa caaagggaaa tcaaatagag aaattgcctc tctacttgga aaagctcctc
    73801 aaactatcca cactgaaatc aagcgt
//
LOCUS       DBEJZJ010000007        72345 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000007 DBEJZJ010000000
VERSION     DBEJZJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 72345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.07"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            425..1316
                     /locus_tag="ACL3R8_000563"
                     /pseudo
     CDS             425..1316
                     /locus_tag="ACL3R8_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            1332..2060
                     /locus_tag="ACL3R8_000564"
     CDS             1332..2060
                     /locus_tag="ACL3R8_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313498.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2446..2655
                     /locus_tag="ACL3R8_000565"
     CDS             2446..2655
                     /locus_tag="ACL3R8_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1313499.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2645..3133
                     /locus_tag="ACL3R8_000566"
     CDS             2645..3133
                     /locus_tag="ACL3R8_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR1313500.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            3249..4709
                     /locus_tag="ACL3R8_000567"
     CDS             3249..4709
                     /locus_tag="ACL3R8_000567"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR1313501.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGAQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4706..5530
                     /gene="nadE"
                     /locus_tag="ACL3R8_000568"
     CDS             4706..5530
                     /gene="nadE"
                     /locus_tag="ACL3R8_000568"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR1313502.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5880..6431
                     /locus_tag="ACL3R8_000569"
     CDS             5880..6431
                     /locus_tag="ACL3R8_000569"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313503.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWA
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            7476..7703
                     /locus_tag="ACL3R8_000570"
     CDS             7476..7703
                     /locus_tag="ACL3R8_000570"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR1313504.1"
                     /translation="MKVPAESKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVT
                     TITYNVDGKSGQVTESTLSQKKDSQTRVVKK"
     gene            7892..8281
                     /locus_tag="ACL3R8_000571"
     CDS             7892..8281
                     /locus_tag="ACL3R8_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR1313505.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(8942..9970)
                     /gene="queA"
                     /locus_tag="ACL3R8_000572"
     CDS             complement(8942..9970)
                     /gene="queA"
                     /locus_tag="ACL3R8_000572"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR1313506.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            10121..10828
                     /locus_tag="ACL3R8_000573"
     CDS             10121..10828
                     /locus_tag="ACL3R8_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR1313507.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            10968..11144
                     /gene="rpsU"
                     /locus_tag="ACL3R8_000574"
     CDS             10968..11144
                     /gene="rpsU"
                     /locus_tag="ACL3R8_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR1313508.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            11274..12209
                     /gene="hprK"
                     /locus_tag="ACL3R8_000575"
     CDS             11274..12209
                     /gene="hprK"
                     /locus_tag="ACL3R8_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR1313509.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            12202..12990
                     /gene="lgt"
                     /locus_tag="ACL3R8_000576"
     CDS             12202..12990
                     /gene="lgt"
                     /locus_tag="ACL3R8_000576"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR1313510.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            12991..13417
                     /locus_tag="ACL3R8_000577"
                     /pseudo
     CDS             12991..13417
                     /locus_tag="ACL3R8_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            13390..13779
                     /locus_tag="ACL3R8_000578"
     CDS             13390..13779
                     /locus_tag="ACL3R8_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR1313511.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            13863..14993
                     /gene="hemW"
                     /locus_tag="ACL3R8_000579"
     CDS             13863..14993
                     /gene="hemW"
                     /locus_tag="ACL3R8_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR1313512.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLNAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            14998..15735
                     /locus_tag="ACL3R8_000580"
     CDS             14998..15735
                     /locus_tag="ACL3R8_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR1313513.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            15746..16519
                     /locus_tag="ACL3R8_000581"
     CDS             15746..16519
                     /locus_tag="ACL3R8_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR1313514.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            16509..17126
                     /locus_tag="ACL3R8_000582"
     CDS             16509..17126
                     /locus_tag="ACL3R8_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR1313515.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            17336..17737
                     /locus_tag="ACL3R8_000583"
     CDS             17336..17737
                     /locus_tag="ACL3R8_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR1313516.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            17737..18015
                     /locus_tag="ACL3R8_000584"
     CDS             17737..18015
                     /locus_tag="ACL3R8_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR1313517.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            18005..18778
                     /locus_tag="ACL3R8_000585"
     CDS             18005..18778
                     /locus_tag="ACL3R8_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR1313518.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            18779..20083
                     /locus_tag="ACL3R8_000586"
     CDS             18779..20083
                     /locus_tag="ACL3R8_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR1313519.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            20657..21535
                     /gene="pstS"
                     /locus_tag="ACL3R8_000587"
     CDS             20657..21535
                     /gene="pstS"
                     /locus_tag="ACL3R8_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR1313520.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            21535..22452
                     /gene="pstC"
                     /locus_tag="ACL3R8_000588"
     CDS             21535..22452
                     /gene="pstC"
                     /locus_tag="ACL3R8_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR1313521.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            22442..23326
                     /gene="pstA"
                     /locus_tag="ACL3R8_000589"
     CDS             22442..23326
                     /gene="pstA"
                     /locus_tag="ACL3R8_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR1313522.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            23337..24140
                     /gene="pstB"
                     /locus_tag="ACL3R8_000590"
     CDS             23337..24140
                     /gene="pstB"
                     /locus_tag="ACL3R8_000590"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1313523.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            24153..24911
                     /gene="pstB"
                     /locus_tag="ACL3R8_000591"
     CDS             24153..24911
                     /gene="pstB"
                     /locus_tag="ACL3R8_000591"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1313524.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            24923..25576
                     /gene="phoU"
                     /locus_tag="ACL3R8_000592"
     CDS             24923..25576
                     /gene="phoU"
                     /locus_tag="ACL3R8_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR1313525.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            25733..26548
                     /locus_tag="ACL3R8_000593"
     CDS             25733..26548
                     /locus_tag="ACL3R8_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313526.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(26568..27839)
                     /locus_tag="ACL3R8_000594"
     CDS             complement(26568..27839)
                     /locus_tag="ACL3R8_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR1313527.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            27981..28712
                     /gene="budA"
                     /locus_tag="ACL3R8_000595"
     CDS             27981..28712
                     /gene="budA"
                     /locus_tag="ACL3R8_000595"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR1313528.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            28722..29475
                     /locus_tag="ACL3R8_000596"
                     /pseudo
     CDS             28722..29475
                     /locus_tag="ACL3R8_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            29587..30537
                     /gene="murB"
                     /locus_tag="ACL3R8_000597"
     CDS             29587..30537
                     /gene="murB"
                     /locus_tag="ACL3R8_000597"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR1313529.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            30596..31753
                     /locus_tag="ACL3R8_000598"
     CDS             30596..31753
                     /locus_tag="ACL3R8_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313530.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            31734..32540
                     /locus_tag="ACL3R8_000599"
     CDS             31734..32540
                     /locus_tag="ACL3R8_000599"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313531.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            32537..33310
                     /locus_tag="ACL3R8_000600"
     CDS             32537..33310
                     /locus_tag="ACL3R8_000600"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313532.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            33307..34377
                     /locus_tag="ACL3R8_000601"
     CDS             33307..34377
                     /locus_tag="ACL3R8_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313533.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            34638..34877
                     /locus_tag="ACL3R8_000602"
     CDS             34638..34877
                     /locus_tag="ACL3R8_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313534.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            35152..35637
                     /locus_tag="ACL3R8_000603"
     CDS             35152..35637
                     /locus_tag="ACL3R8_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR1313535.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            35659..38277
                     /gene="alaS"
                     /locus_tag="ACL3R8_000604"
     CDS             35659..38277
                     /gene="alaS"
                     /locus_tag="ACL3R8_000604"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR1313536.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GNIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQLSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGR
                     NQAKIQELLDAVAGKL"
     gene            complement(38367..39821)
                     /locus_tag="ACL3R8_000605"
     CDS             complement(38367..39821)
                     /locus_tag="ACL3R8_000605"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR1313537.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFIDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            40000..40749
                     /locus_tag="ACL3R8_000606"
     CDS             40000..40749
                     /locus_tag="ACL3R8_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313538.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            40730..42364
                     /locus_tag="ACL3R8_000607"
     CDS             40730..42364
                     /locus_tag="ACL3R8_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313539.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYRSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            43048..44211
                     /locus_tag="ACL3R8_000608"
     CDS             43048..44211
                     /locus_tag="ACL3R8_000608"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR1313540.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            44208..44885
                     /gene="aroD"
                     /locus_tag="ACL3R8_000609"
     CDS             44208..44885
                     /gene="aroD"
                     /locus_tag="ACL3R8_000609"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR1313541.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            44875..45729
                     /locus_tag="ACL3R8_000610"
     CDS             44875..45729
                     /locus_tag="ACL3R8_000610"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR1313542.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            45748..46815
                     /gene="aroB"
                     /locus_tag="ACL3R8_000611"
     CDS             45748..46815
                     /gene="aroB"
                     /locus_tag="ACL3R8_000611"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR1313543.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            46825..47991
                     /gene="aroC"
                     /locus_tag="ACL3R8_000612"
     CDS             46825..47991
                     /gene="aroC"
                     /locus_tag="ACL3R8_000612"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR1313544.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            48001..49104
                     /locus_tag="ACL3R8_000613"
     CDS             48001..49104
                     /locus_tag="ACL3R8_000613"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR1313545.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            49115..49453
                     /locus_tag="ACL3R8_000614"
     CDS             49115..49453
                     /locus_tag="ACL3R8_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR1313546.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            49545..50828
                     /gene="aroA"
                     /locus_tag="ACL3R8_000615"
     CDS             49545..50828
                     /gene="aroA"
                     /locus_tag="ACL3R8_000615"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR1313547.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            50821..51297
                     /locus_tag="ACL3R8_000616"
     CDS             50821..51297
                     /locus_tag="ACL3R8_000616"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR1313548.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            51294..52142
                     /gene="pheA"
                     /locus_tag="ACL3R8_000617"
     CDS             51294..52142
                     /gene="pheA"
                     /locus_tag="ACL3R8_000617"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR1313549.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            52139..53413
                     /gene="psr"
                     /locus_tag="ACL3R8_000618"
     CDS             52139..53413
                     /gene="psr"
                     /locus_tag="ACL3R8_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR1313550.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            53692..54537
                     /locus_tag="ACL3R8_000619"
     CDS             53692..54537
                     /locus_tag="ACL3R8_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1313551.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVVFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            54527..55630
                     /locus_tag="ACL3R8_000620"
     CDS             54527..55630
                     /locus_tag="ACL3R8_000620"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1313552.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            55632..56618
                     /locus_tag="ACL3R8_000621"
     CDS             55632..56618
                     /locus_tag="ACL3R8_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1313553.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            56634..58067
                     /locus_tag="ACL3R8_000622"
     CDS             56634..58067
                     /locus_tag="ACL3R8_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR1313554.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            58096..59130
                     /locus_tag="ACL3R8_000623"
     CDS             58096..59130
                     /locus_tag="ACL3R8_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR1313555.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            59272..60009
                     /gene="mecA"
                     /locus_tag="ACL3R8_000624"
     CDS             59272..60009
                     /gene="mecA"
                     /locus_tag="ACL3R8_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR1313556.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            60159..61445
                     /locus_tag="ACL3R8_000625"
     CDS             60159..61445
                     /locus_tag="ACL3R8_000625"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR1313557.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            61447..62316
                     /gene="thrB"
                     /locus_tag="ACL3R8_000626"
     CDS             61447..62316
                     /gene="thrB"
                     /locus_tag="ACL3R8_000626"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR1313558.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGSTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            62656..63594
                     /gene="msrB"
                     /locus_tag="ACL3R8_000627"
     CDS             62656..63594
                     /gene="msrB"
                     /locus_tag="ACL3R8_000627"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR1313559.1"
                     /translation="MTEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            63652..65376
                     /locus_tag="ACL3R8_000628"
     CDS             63652..65376
                     /locus_tag="ACL3R8_000628"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313560.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            65378..67126
                     /locus_tag="ACL3R8_000629"
     CDS             65378..67126
                     /locus_tag="ACL3R8_000629"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313561.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFVKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            67428..68687
                     /locus_tag="ACL3R8_000630"
     CDS             67428..68687
                     /locus_tag="ACL3R8_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR1313562.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    68763..68898
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            68937..69437
                     /gene="rplJ"
                     /locus_tag="ACL3R8_000631"
     CDS             68937..69437
                     /gene="rplJ"
                     /locus_tag="ACL3R8_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR1313563.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            69513..69881
                     /gene="rplL"
                     /locus_tag="ACL3R8_000632"
     CDS             69513..69881
                     /gene="rplL"
                     /locus_tag="ACL3R8_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR1313564.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            70068..70238
                     /locus_tag="ACL3R8_000633"
     CDS             70068..70238
                     /locus_tag="ACL3R8_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313565.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            70238..70486
                     /locus_tag="ACL3R8_000634"
                     /pseudo
     CDS             70238..70486
                     /locus_tag="ACL3R8_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            70500..70840
                     /locus_tag="ACL3R8_000635"
                     /pseudo
     CDS             70500..70840
                     /locus_tag="ACL3R8_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            70833..71213
                     /locus_tag="ACL3R8_000636"
     CDS             70833..71213
                     /locus_tag="ACL3R8_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR1313566.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            71226..71459
                     /locus_tag="ACL3R8_000637"
                     /pseudo
     CDS             71226..71459
                     /locus_tag="ACL3R8_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            71462..72049
                     /locus_tag="ACL3R8_000638"
     CDS             71462..72049
                     /locus_tag="ACL3R8_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1313567.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            72251..>72345
                     /locus_tag="ACL3R8_000639"
     CDS             72251..>72345
                     /locus_tag="ACL3R8_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR1313568.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT        21175 a        13351 c        16236 g        21583 t
ORIGIN      
        1 gttcaagctg gagacatggt tcgagctctt aaagaggggc ttatcaatct ttataaggaa
       61 gatggaacca gcgtcacagt tcgtgcttaa tgtagttgtt tagttttaaa aaattatgca
      121 aagctccata tacaacactt aaacgagatt aaagaatggc gaaatccctt gatgcgcaag
      181 ggattagctg tcttttttat tttttaagtg ataaagtcgg agcttaggta tcaaagccta
      241 tcaaattaaa caaagaagcg atgtcttaga tattttgaaa aaaattaata agcagaaaac
      301 tctctattat tttgttgtag agagtttttt gttaataaaa ttttacaaaa tgacatttat
      361 atattgcatt aagttagata tatgatataa tgttgttaaa aagaggcgca actttttaaa
      421 ctcaataaga atcaaagagc aaaccgagaa tattaatgga ggaataaaaa atgtaagtta
      481 taaatgtaag taagcattat ggtcattcaa tcattctcaa agatataaat tttgcactta
      541 acaagggtga aattgttggt ctagtaggga gaaacggagt tggtaagagt acattgatga
      601 aaattcttgt tcagaataat caaccgactt cagggaatat tataagtagt gataatgttg
      661 ggtatttaat tgaagaacca aaattatttt tatctaaaac aggtttagag aatttaaaat
      721 atctggcaaa cttatatggt gttgactaca atcaagaaag atttagaagt ttgatccaag
      781 agttagattt gactcagtct attaataaaa aagtaaagac ctattctttg ggtacaaaac
      841 aaaaattagc tttgcttcta actctcgtta cgaaacctga tatattgatt ttagatgaac
      901 cgactaatgg tttagatatt gaatcatcac aaatagtttt agcggttcta aaaaaattag
      961 ctttaaatga aaacgtggga attttaatat cgagtcataa attagaagac attgaagaaa
     1021 tttgtgagag agttcttttc ttggagaacg ggcttttgac atttcaaaaa gtaggaaaag
     1081 atagtcataa tttcttgttt gagatagctt tttcatcagc tacagataga gacattttca
     1141 ttaccaaaca agaatttggg gatattgttc aggaagaggg attgagaatt actatgtctg
     1201 ggaatattca aagtagtgag ctttttaaat tttttaacga aaactctatt aaagtagttg
     1261 attttgaaac taaaaaagag acgcttaaag atatttacct aaatcgttca aaataaagga
     1321 aggttataat catgaaatta aataaattga attttcttaa ggaaaatata agaaatttat
     1381 attcatcagg cgtaatatat ctcggtttgc ttatctcgtt tataccgccg atattgctta
     1441 cattctttat tctaaagact caagggacat cgcttggtat taagcatatt tcaaactttt
     1501 atgctatgct cggtatgtta atggctgtta tacatgctaa tcgagtcatt agtagagatt
     1561 tttcccacaa tacggtaagt ttgttttata atcaacagaa gaatcggatg atttacgtct
     1621 tgtctaattt tctatatgcc atctcagttt ccattattta tgctttgaat ggcattgtgt
     1681 tactagtcat agtaagtaaa ttgggtattc caggtgattt aggattagat tttatagtag
     1741 ctattgtagt caatacaatt ttgttagtcc tgttttattt tctattatct tacattttct
     1801 atttatacaa attgaaaagt ggcttggtat ttggtatttt agtagcttta ctactcttta
     1861 tccctaatat attaaatacg atgatgatga atactagtaa tgatttgttt atcaaagcaa
     1921 ttgaacttct tcctttttat tctttacctg tatttgtggc ttcaaatacg atgtctatta
     1981 gtcagtatct tgtggtaatc actacaatca ttttattgta ctttttcact ctcaagaaaa
     2041 gcaagaagta ttcattttag tttcatttag tattattttg catacctaaa atacaataaa
     2101 aaaatcagtc atcttggtat gctcctgctt tcactattca acacgttttt gacttatact
     2161 aggctcattt ccaaaagcat tatataatag tgatatgaaa ccaactaaac taaacaagaa
     2221 atataagcaa taaaaactcg tttaaaagat tctactaaag ctaatactaa ataaaaataa
     2281 aagagtaaac taggaagttt atttcaaaca acctaaaata ctgattttcg gctgaagata
     2341 atactggagt gcaaattaat ggggttataa taaatagctg atagcttgtg ttggttttgg
     2401 attttttaag agtagatgag tattaaaact ataaggagga cgaaggtggc taaaaattta
     2461 aaattaaaat tagctcgggt agagcgtgat ttaacacaag gtcaactggc agaggctgtc
     2521 ggggtgacac gccagactat tggtttgata gaggcgggaa aatacaatcc cagtctctcg
     2581 ctctgccagt ctatttgcag atgtttaggg aaaaccctag accaactatt ttgggaggaa
     2641 gaagatgaaa aatagatttt attattatca attactagac gaaagagaag aacaactgtt
     2701 caataaagcg ggatctgaaa gtttctatat ctgcattgct ttgtcgctcc tatcttatat
     2761 catttcagta ttagcaccaa gcctttttaa ttctaatatg ctgctaatcg ttatcatcat
     2821 agggacattt tactttttca atcgcgcccg ttatctggga gtgacctact atagtcgttt
     2881 tcattttacg attttgggtt gttttttcct aaccttggct attacggctc ttttgatgtt
     2941 gcagaattat caattcaaca tagaaattta tcagcacaat cctttgaatt ttaaatacct
     3001 gtctgcttgg gtcattactt atgtcattta ccttccgtgg gtctttattg gcaatcttgg
     3061 tcttaagagc tatggcgaat gggctcagaa aaaatttgaa caagatatgg atgaattgga
     3121 gagtggagaa tagcttgtta ctcttttctc aatccagcta aaatgtgata taatagtact
     3181 aatttattgg aatacatgaa agttcttgaa aattttcatg tgtttctagc taaggaagta
     3241 ggaaaagtat gtatccagat gatagtttga cattgcacac ggacttgtac cagatcaaca
     3301 tgatgcaggt ttactttgac caagggattc acaataagaa ggcggtcttt gaggtgtatt
     3361 tccgccaaca gccttttaag aacggctatg cggtttttgc aggtttggaa agaattgtga
     3421 actatcttga agacttgcgt ttttcagata gtgatatagc ctatttggag tcgcttggtt
     3481 atcatggggc gttcttggat taccttcgca atttcaagtt ggagttgacc gttcgttctg
     3541 cccaagaagg ggatttggtt tttgctaatg aaccgattgt gcaggtggaa ggacctctag
     3601 cccaatgtca gttggtcgaa acggctcttt tgaacatcgt caactaccag accttggtgg
     3661 cgacgaaggc agctcgtatt cgttcggtta tcgaagatga acccttgatg gagtttggga
     3721 cacgtcgggc tcaagaaatg gatgcggcca tctggggaac acgcgcagcg gtgattggtg
     3781 gggccaatgg aaccagcaac gtgcgtgcgg gtaagctctt tgacattcct gttttgggaa
     3841 cccatgccca tgccttggta caggtttatg gcaatgacta tgaagctttc aaggcttacg
     3901 ctgcgaccca caaaaattgt gtctttcttg tggacaccta tgacaccctt cgcatcggtg
     3961 taccagctgc cattcaggtg gcgcgtgagc tgggtgctca gattaacttt atgggtgtgc
     4021 ggattgactc tggggatatt gcctacattt ctaagaaagt ccgtcagcaa ctggacgagg
     4081 ctggatttac agaggctaag atttatgctt ctaatgattt ggacgaaaat actatcctca
     4141 atctcaagat gcaaaaggcc aagattgatg tctggggcgt gggtaccaag ctgattacag
     4201 cttatgacca gccagctctt ggtgcagttt acaagattgt tgcaatcgaa gatgaaactg
     4261 gtcagatgcg caatacgatt aagctgtcta ataatgctga aaaagtttct acgccaggta
     4321 agaagcaggt gtggcgcatt accagtcgtg aaaaaggcaa gtcagaaggt gactacatca
     4381 cttatgatgg tgtggatatt agcgacatga cagaaatcaa gatgttccat ccgacctata
     4441 catacatcaa gaagacggtt cgtaattttg atgccgttcc tctcttggtg gatatcttca
     4501 aagaaggaat attagtttac aacttgccta gtttgactga cattcaggat tatgcccgta
     4561 aggaatttga caagttgtgg gatgagtata agcgtgtgct caatccgcag cactatccag
     4621 tggatttggc gcgtgacgta tggcaagata agatggactt gattgataag atgcgcaagg
     4681 aagcccttgg tgaaggagaa gaagaatgag tttgcaagaa acgattatcc aagagctggg
     4741 tgtcaaacca gtgattgatg cccaggaaga aatccgtcgt tctattgatt tcttaaaaag
     4801 atatctgaaa aaacatccct tcctaaaaac ctttgtacta gggatttctg ggggacaaga
     4861 ctcaaccttg gcaggacgtt tggcgcaatt agctatggaa gaactgcgag ctgaaacggg
     4921 agacgatagc tacaaattta tcgctgtccg cctgccatac ggagtgcaag ctgatgaagc
     4981 agatgctcaa aaagccctag ccttcatcca gccagatgtc agcttggttg tgaatatcaa
     5041 ggaatcagct gatgccatga cagctgcagt tgaagcgaca ggtagtcctg tttcagactt
     5101 caacaagggg aatatcaagg cacgttgccg tatgattgct cagtatgccc ttgctggttc
     5161 ccatagcgga gcggtcattg gaacagacca cgccgcagaa aatatcacag gtttctttac
     5221 caagtttggt gacggcggtg cggatattct ccctctttac cgcctcaata aacgccaagg
     5281 aaaacagctc ttgcagaaac ttggcgcaga gccagccctt tatgaaaaaa tcccaacggc
     5341 agacctagaa gaagataaac caggcctagc tgacgaagtc gcacttggag tcacctacgc
     5401 agagattgac gactacctag aaggcaaaac aatcagccca gaagctcaag cgaccattga
     5461 aaactggtgg cacaaaggcc aacacaaacg ccacttaccc atcaccgtat ttgatgactt
     5521 ttgggagtaa aaaggtccgg gggacctttt tagcttcttg ccctgaaatt aaaaagcaag
     5581 aaaaacctcc actggaggtt ttcagcctct catcttgaaa taagaaagtg agagaaggtc
     5641 cgggggatct tgaacctcga gtttagaaat aagaaaatga ggcagattcg gtaactcgaa
     5701 gagttcgatt tcatcgtctt acccctgcaa cgatgactag gtttgaaaaa gcttgctaga
     5761 tcgcatttca aaccaggcag cgactgcgtc aagaaattag aagacaaact cgttttctag
     5821 ctgttactga gttgagcctt tttactacga gcatagaaat aaggaagtga ggtagcatca
     5881 tgaaatctat tggtacgcaa atattacaga cagaacgttt gattttaaga agatttgtgg
     5941 agagtgatgc agaagccatg tttcaaaatt gggcttcatc cgctgagaat ctgacctatg
     6001 ttacctgggc tccccatcct gatgtcgaaa tcactcgaaa ctcgattcgc aattgggttg
     6061 cttcctatac taatctcaac tattacaaat gggccatttg tctaaaagaa aacccagagc
     6121 aagtgatagg agatatcagc atcgttaaga tagacgaggc tgatttaagc tgtgaaatcg
     6181 gctatgtgct aggcaaggct tactggggac atggtatgat gacagaggcc ttgaaagctg
     6241 tcttggactt ttgttttact caagcaggtt ttcaaaaggt cagagcacgt tatgccagtc
     6301 tcaacccagc ttcaggtcgt gtcatggaaa aggctggaat gtcctatcta caaaccattg
     6361 ttaatggtgt agagagaaaa ggctatcttg cggatcttat ttattatggt ataagtaggg
     6421 aagaatgttg aattctattt tctgtttcta tcgaagtcaa ctatttattg taaatataat
     6481 aattagcatt ccaagtttat ttgcaatttt aaaatagcat attgattagt acaagacaga
     6541 tgttctagtt ccttctttaa tctggtttag tattagttaa aaaatcgctt taagcttgta
     6601 actaagaggg agctaatcga ctagattctc cagccgaaca ggtggtaatg tactttttat
     6661 agtgtaatcc tagctgttgt taaatttaaa atagaatcct ctatcgagtt agggaattaa
     6721 attcaaccaa ttttatttat gttttttcta tcaaattatc taatattaaa atagtctcat
     6781 tctgatgaga aaactattct atttatactg catcgttgtg taaggaatga tgaaagatga
     6841 gtgaaaatta tcaagttgga atgtttgtat ctaaatatat tagcatgtat ttagatcaga
     6901 tgtctgcaat cctttatata tgagattgat tacgatatag ttaaagtgtt agttcaatag
     6961 taaatatatc attctaagtc tattttatat ataaagtata ttgtttaacg tttgatagaa
     7021 aagatgctat actagaagta ggatgtaatg gcaaaatcta atactaataa gcgctatgca
     7081 atacgtaaac tcggaaagat ttttggttct gcggtaatcg ggctaacttt atttttagga
     7141 ggaatctgaa tacaagtttt gctcatgctg ctgatgggat tcaatatgtc agagatgata
     7201 ctagagataa agaagaggga atagagtatg atgacgctga caatggggat attattgtaa
     7261 aagtagcgac taaacctaag gtagtaacca agaaaatttc aagtacgcga attcgttttg
     7321 aaaaagatga aacaaaatac cgtagtgaaa atcctgttac aattgacgga gaggatggct
     7381 atgtaaccac gacaaggacc tacgatgtta atctagagac tggtcatgtt accgaacagg
     7441 ttactgttga tagaaaagaa gccacggata cagttatcaa agttccagct gaaagcaagg
     7501 ttgaagaagt tcttgttcca tgtgctacta aatatgaagc agacaatgac ctttctgcag
     7561 gacaggagca agagattact ctaggaaaga atgggaaaac agttacaacg ataacttata
     7621 atgtagatgg aaagagtgga caagtaactg agagtacttt aagtcaaaaa aaagactctc
     7681 aaacaagagt tgttaaaaaa tgaaccaagc cccaagttct tgtccaagaa attccaatcg
     7741 aaacagaata tctcgatggc ccaactcttg ataaaagtca agaagtagaa gaagtaggag
     7801 aaattggtaa attactctta ctacaatcta tactgtagat gaacgtgatg gaacaattga
     7861 agaaactact tctcgtcaaa ttactaaaga gatggtaaaa agacgtataa ggagagggac
     7921 gagagaacct gaaaaagttg ttgttcctga gcaatcatct attccttcgt atcctgtatc
     7981 tgttacatct aaccaaggaa cagatgtagc agtagaacca gctaaagcag ttgctccaac
     8041 aacagactgg aaacaagaaa atggtatgtg gtatttttat aatactgatg gttccatggc
     8101 aacaggttgg gtacaagtta atggttcatg gtactacctc aacagcaacg gttctatgaa
     8161 agtcaatcaa tggttccaag ttggtggtaa atggtattat gtaaatgcat cgggtgagtt
     8221 agcggtcaat acaagtatag atggctatag agtcaatgat aatggtgaat gggtgcgtta
     8281 acagattcct ccctgcgaca aaattgataa tagtatgtct gaatatataa ttatatataa
     8341 aaagctatag ataaggtcat cttatagcga ctataaaaaa gtgaacaagc ctagtcttct
     8401 gtacattaga attcagattt gttcactttt tgtttaatac tcaatgaaaa tcaaagagca
     8461 aactagaaaa ctagtcgcag gttgctcaaa gtactgcttt gaggttgtag atagaactga
     8521 cgaagtcagt cacatatata atccaaggtg acgttgacgc ggtttgaaga gatttttgaa
     8581 gagtataagt ctttgatttt gagactaagg agagtcaggg tcaaagtagt gaatgattct
     8641 gaaataactc ataatagtct cttgagagga cagataagag taacaaatat ggtgctactc
     8701 atgtgtcttg cattttgatt tacaaacagc gaagaaaata taggaagctg aaataaaata
     8761 tagatgaatc aatttggaga gtcaacgcaa tctatggcaa tattttcgaa gctaggggga
     8821 agcattttaa tttcaatgta ctaggcgtct tctacagcta gctagagttt caattgtaga
     8881 tgttctttga aataatatct tagcgattta ttggtattag aagaattaga gaaattcttt
     8941 ctcaataaat aaacatggcg tcaccaaaac tgaagaagcg gtagtgttct tggatggcat
     9001 ggtggtaggc atctaagact aattcacggc ctgcaaaggc agaaaccaac atgaccagag
     9061 ttgattttgg cagatggaag ttggttgaga aggcatccac gaccttccac tcatacccag
     9121 gtttgataaa gatattggtc caaccagaat ctgcttggat ttgcccatca aacttggaac
     9181 caatagtttc caaggtgcgg atagaagtgg ttccgacagc gatgacgcga ccaccatttt
     9241 ctttgacaga gcgaagggtg gcagcagctt cctcagaaag ttgatagaac tctgagtgca
     9301 tttcgtgttc gtccagatta tccacagaaa caggtctaaa ggttccgagt ccgacatgga
     9361 gagtcagata gactagatga acacccttag cttggatttc tgccagcagt tctttggtga
     9421 agtgaagacc agcagtcggt gctgcagcag agccgctttc cttggcgtag acggtttgat
     9481 aacgttcacg gtcatctaat ttttcgtgga tataaggtgg cagaggcatt tctcccagac
     9541 tttccaagac ttctaggaaa attccttggt attcaaagcg gacaatgcgt cccccgtggg
     9601 tcaattcttc tgtaacgaca gcgctgaggc ggccatcacc aaagctgata cgagtaccga
     9661 ccttgaggcg tttggcaggt ttagccagaa cttcccactc gtctccacta gtgttcttaa
     9721 ggaggagaag ttccacatga cctcctgtct ccactttttg accatagagg cgggcaggga
     9781 gaactcgggt gtcgttcatg acaagggcat caccaggttc cagcatatca ataatagagt
     9841 ggaaatgttt atcttgcatt tctcctgtct cacggttgac gatgaggagt ttggaggcat
     9901 cacgtttttc aaggggcgtt tgggcaatca attcctctgg caagtggaaa tcaaaatcag
     9961 ctgtattcat atatttgttc attctttcta agttctaatc ctatccatta taacacgttt
    10021 caagtttgga cgctcttttt ttagaaatta aatcgttttc acttgacaaa aattggtcta
    10081 taccatataa taaatataga cagaaatgga ggatgaaaag atgaaagtta ttaaagttga
    10141 aaaccaagtt caaggtggaa aagttgcttt tgagattttg aaggaaaaat tggctaatgg
    10201 agctcaaact ctaggacttg cgacaggaag tagcccactt gaattttaca aggaaattgt
    10261 tgagagtgac cttgattttt caaatctaac cagtgtcaac cttgatgagt atgtgggcct
    10321 tgatggggac aatccacagt cttatcgtta cttcatgcaa gaaaacttgt tcaaccaaaa
    10381 accatttaaa gaaagtttct tgcctcgtgg tgttaaggac aatgctgaag ctgaagttga
    10441 acgctacaac caaattttgg ctgaccatcc agttgacctc caaatcttgg gaatcggtcg
    10501 caatgggcat atcggcttta atgagcctgg tactccattt gacagtcaaa cgcatctagt
    10561 agaacttgac cagtctacta tcgaagccaa tgcacgcttc tttgccaaga ttgaagacgt
    10621 cccaacccaa gctatttcaa tggggattaa aaacattttg gatgccaagt ctattattct
    10681 ttttgcttac ggtgagtcga aagcagaagc cattgccgga acagtatctg gcccagtgac
    10741 tgagaaccta cctgcaagta gcctccaaaa tcaccctgat gtaaccatca tcgcagatgc
    10801 tgaagcgctt agcttactcg aaaaataaaa aagcaatgtt ctattgaacg ctttcaactc
    10861 ttgtataaat ggaagaaaaa atcaaaatta aaccgcattt ttgcttgaca attattcctt
    10921 ttacgtgtag aatgaaatag atcttgaact tgaagggagt gaaaaaaatg tctaaaacag
    10981 tagtacgtaa gaatgaatct cttgacgacg cacttcgccg tttcaaacgt gcggttacta
    11041 aagctggtac tcttcaagaa acacgcaaac gtgaattcta tgaaaaacct tctgtaaaac
    11101 gtaaacgtaa atcagaagta gctcgtaaac gtaaaaaatt ctaattgaaa tgaaaggcta
    11161 gagaaatcta gtcctttttc ttttaaataa atactccaaa gcctgcaaaa atctgaaact
    11221 tcctcctaca atttgatata atagagagaa gaactcattt gaaggaggaa atgatgtcgg
    11281 ttttagtaaa agaagtgatt gaaaagctta gactagacat tgtctatggt gaaccagaat
    11341 tgcttgaaaa ggaaatcaat acagcggata ttacgcgacc tggtcttgaa atgacaggct
    11401 attttgacta ctatacacca gagcggattc aacttttggg gatgaaggag tggtcttatc
    11461 tgatcagcat gccttccaac agccgttatg aagttttgaa aaaaatgttt ctacctgaga
    11521 caccagcagt cattgttgcc cgtggtttgg tggttccaga ggagatgtta aaggctgcta
    11581 gagaatgtaa gattgctatt ttaaccagcc gtgcagctac cagtcgttta tctggagagt
    11641 tatctagcta tctggattct cgtttggcag aacgtaccag tgtgcacggt gtcttgatgg
    11701 atatttatgg gatgggcgtc ttgattcagg gagatagtgg aattggtaag agcgagacag
    11761 gtcttgagct tgtcaaacgt ggtcaccgtt tggtagccga tgaccgtgtc gatatctttg
    11821 ccaaggatga gattactctc tggggtgaac cggctgaaat tttgaaacac ttgattgaaa
    11881 ttcgtggggt tggtattatc gatgttatga gtctctacgg tgcgagtgct gtcaaggatt
    11941 cttcacaggt tcagcttgct gtctatttgg aaaattacga tacgcataag acctttgatc
    12001 gtcttggaaa caatgcagag gaacttgaag tttctggcgt agccattcct cgtattcgta
    12061 ttccagttaa aacaggtcgt aatatctctg ttgtgattga ggcagctgcc atgaattatc
    12121 gtgccaagga aatgggcttt gatgctaccc gtttgttcga cgaacgactg acaagtctca
    12181 tagctcgaaa tgaggtgcaa aatgcttgat ccaattgcta ttcaactagg acccctagcc
    12241 attcgttggt atgccttatg tattgtgaca ggcttgattc ttgcggttta tttgaccatg
    12301 aaagaagcac ctagaaagaa gatcatacca gacgatattt tagattttat cttagtagcc
    12361 tttcccttgg ctattttagg agctcgtctc tactatgtta ttttccgatt tgattactat
    12421 agtcagaatt taggagagat ttttgccatt tggaatggtg gtttggccat ttacggtggt
    12481 ttgataactg gggctcttgt gctctatatc tttgctgacc gtaaactcat caatacttgg
    12541 gattttctag atattgcggc gcctagcgtt atgattgctc aaagtttggg gcgttggggt
    12601 aatttcttta accaagaagc ttatggtgca acagtggata atctggatta tctacctggc
    12661 tttatccgtg accagatgta tattgagggg agctaccgtc aaccgacttt cctttatgag
    12721 tctctatgga atctgcttgg ctttgccttg attctgattt ttagacggaa atggaagagt
    12781 ctcagacgag gtcatatcac ggccttttac ttgatttggt atggtttcgg tcgtatggtc
    12841 atcgaaggta tgcgaacaga tagtctcatg ttcttcggcc ttcgagtgtc ccaatggctg
    12901 tcagttgtcc ttatcggtct cggtataatg atcgttattt atcaaaatcg aaagaaggcc
    12961 ccttactata ttacagagga ggaaaactaa atgttagaag ttgcatatat tcttgttgcc
    13021 ctagctttaa ttgtcttttt ggtctatctg atcattactg tacaaaagct tggtcgtgtc
    13081 atcgatgaaa cagaaaagac gattaaaacc ttgacttcag atgtggatgt gaccttgcat
    13141 cacaccaatg agttgttggc taaggtcaat gtcttggcag atgatatcaa tgtcaaggtg
    13201 gctacgattg atccactctt cagtgctgtt gcagatttat ctctatctgt ttcagacctc
    13261 aatgaccatg cgcgtgtctt gagcaagaaa gcttcatcag ctggttcaaa aacactcaag
    13321 actggtgcaa gtctgtcagc tcttcgtctt gcaagtaaat ttttcaaaaa ataaaaaagg
    13381 agaatcctta tgggtaaatt atcctcaatc cttttaggaa cggtttcagg tgcagctctt
    13441 gccttgtttt taacaagtga taagggcaaa caagtttgca gtcaggctca agattttcta
    13501 gatgatttga gagaagatcc ggagtatgcc aaggagcaag tctgtgaaaa actgacagaa
    13561 gttaaggagc aggctacaga ttttgttctg aaaacaaaag aacaggttga gtcaggtgaa
    13621 atcactgtgg acagtatact tgctcaagct aaatcctatg cttttcaagc gacagaagca
    13681 tcaaaaaatc aattaaataa tctcaaggaa caatggcaag aaaaagccga agctcttgat
    13741 gactcagaag agattgtgat tgatataaca gaagaataaa ccatcaccat ctccggacgg
    13801 actatgtatc tggggatggt gatttttatc tggaatctag tctttgtggt ataataatta
    13861 ctatgcagaa aaaaccaacg tcagcctatg tgcacatccc attttgtacc cagatttgtt
    13921 attattgtga tttttcaaag gtcttcatca aaaatcagcc agtcgacagc tatttagagc
    13981 atctgctgga agagtttcgt tcttatgata ttgaaaagtt gtcaaccctt tatatcggtg
    14041 gtggaacacc gacagccctg tcggctccgc aactggaggt tttactgaat ggcttgacta
    14101 aaaacttgga cttgtctgtc ttagaagagt tgaccattga agccaatcca ggcgatttga
    14161 atgcggataa gatagctgtt ttgaaaaatt cggctgtcaa tcgtgtttcg ctaggtgtcc
    14221 agacctttga tgataagatg ttgaaaaaga ttgggcgcag tcatttggag aaggatattt
    14281 atgaaaatat cgatcgcctg aaactggctg gttttgacaa catctccatt gatttgattt
    14341 atgctctgcc tggtcagacc atggagcaag taaaggaaaa tgtggctaaa gccattggac
    14401 tggatattcc ccacatgagt ttgtatagtt tgattttaga aaaccatacg gtctttatga
    14461 accggatgcg acgtgggaaa ttgcctctgc ctaaggagga actagaagcg gagatgtttg
    14521 agtacatcat tgcagagctg gagcgagcgg gttttgagca ttatgagatt tctaatttct
    14581 ccaaacccgg ctttgaaagt cgtcataatc tcatgtactg ggacaatgct gaatactatg
    14641 gtattggtgc aggggcatct ggttatgtca atggagtacg ttataaaaat catggtccca
    14701 ttcgtcatta tctcagtgcg gttgaggaag gcaatgcttg tattacagaa gatcacctga
    14761 gtcaaaagga gcaaatggaa gaagaaatgt tcttgggact ccgcaagaaa tccggggttt
    14821 ccatggcgcg atttgaggaa aaatttggac agtcttttgc tggactttat ggagaaattg
    14881 tcagagattt ggttcaacaa ggcctcatgc agattgaggg tgaccacgtt cgcatgacaa
    14941 agagaggtct ctttttggga gatactgtag cagaacgatt tattttggag taggatcatg
    15001 ggcttaactt atcaaatgaa aatgaaaatt ccttttgata tggctgatat gaacggtcat
    15061 atcaaacttc cagatgtgat tttgctgtca ctgcaagttt cagggatgca atcgattgaa
    15121 ctgggagtta gtgataaggc cattttggaa gactataatc tggtctggat tatcgcagaa
    15181 tatgatattg aggtggttcg tttgcctcgt tttgcggaag aaattaccat cgaaacggaa
    15241 gccttgagct acaatcgact tttttgctac cgtcgcttta ctatttataa tgaagcgggg
    15301 caggagctca tccatatgat ggcgaccttt gttctcatgg accgcgacag tcgaaaagtc
    15361 catgctgttg aacctgagat tgtggctcct taccagtctg attttgataa aaaacttatc
    15421 cgtggaccga agtatgaatc cttggaagag ccgatcagca aggattacca tgttcgtttt
    15481 tacgacttgg atatgaatgg tcatgtcaat aacagtaaat acttggactg gatttttgag
    15541 gtcatgggag cggatttttt gacccactat attcccaaga aaatcaacct caagtatgtc
    15601 aaggaagttc gaccaggtgg ggtgattaca tcggctgttg aacggactgg actggaaagc
    15661 aagcatgaaa ttacaagtga tggggttatc aatgcccaag caatcattac ttggcaagaa
    15721 ataaaaaagg tttagggaga aatagatgaa atataaaggc tatttaattg atttagacgg
    15781 aaccatttat aaggggaaag accgaatccc tgctggagag acttttgttc atgaattgca
    15841 aaagcgggac attccctatc tctttgtaac caacaataca acccgcactc cagagagtgt
    15901 taaggagatg ttggctcaga attttaatat cgatacgcct ctatcgactg tctacacagc
    15961 gactttggca accatcgact atatgaatga tttggggctt gaaaagactg tctatgtcgt
    16021 cggagaagca ggactcaagg aagccatcaa ggcggctggt tatgtggaag acaaggaaaa
    16081 ccctgcctac gtggtagttg gtctggattg gcaagtcgac tatgaaaaat ttgccacagc
    16141 aactcttgct attcaaaagg gtgcccattt tatcggaacc aatcctgacc tcaacatccc
    16201 gacggaacgt ggtcttttgc caggtgctgg ctcactgatt acgctgcttg aagtagcgac
    16261 acgagtgaag ccggtttata tcggaaaacc aaatgccatc attatggaca aggcggttga
    16321 gcacttaggt ttggaacgtg aagagttaat catggttggg gacaattatt tgactgatat
    16381 ccgggctggg attgacaatg gcattccaac gctcttggtg acgacaggtt ttactaaggc
    16441 agaagaagta gctggcctgc caatcgcacc gacacatgtg gtttctagcc ttgcggagtg
    16501 ggattttgat gaaaactaaa ttgacctttt ggggctctat gctctttctc ctctccctct
    16561 caatccttct gaccatttat ctggcttgga ttttctatcc tatggagatt cagtggctaa
    16621 acttaacgaa tcgagtctat ctaaaaccag aaaccattca atacaatttt catatcttga
    16681 tgaattatct gaccaatcct tttagtcagg tcttacagat gcctgatttt cgttcgtcag
    16741 cagctggtct gcaccatttc gcagtggtca agaatctctt tcatttggtt cagctagtag
    16801 ctctagtgac actgccaagt ttctatgtct ttgtcaatag gattgtgaaa aaggactttt
    16861 tgtctcttta tcgaaaaagt ctcctgactc tagtagtctt acctgtgatg attggacttg
    16921 ggggagtttt gattggtttt gaccaattct ttactctttt ccatcaaatt ctctttgtgg
    16981 gagatgatac ctggcttttt gatccagcca aggatcctgt tattatgatt ttgccagaga
    17041 ccttctttct tcatgccttc ctcctctttt ttgccctcta tgaaagcttc tttgggtatc
    17101 tgtgtctgaa aagtcgtagg aagtgaaatg aaagatgttt ttaatttgca tatataaaaa
    17161 tatatatcgt ttaaaaccat cgttaagagt gaattaacca aatccaattg tgtcaatcgt
    17221 tcgcaaacag cctatttttc ttgaaaaaat aggctttttt tctaaaaatc cctagtcaag
    17281 cgctttattt ttttgtataa tagaagtagc aaagtataga taagaagaga aaagcatgat
    17341 tacactattt ctatcaccga gctgtacatc atgtcgtaag gctaaggcct ggttagaaaa
    17401 acataaggtt ccctttgtgg aacacaatat tatgaccagt cctttaacaa gaaaagaatt
    17461 gcaacacatc ctttccttga ccgaaaatgg tactgatgac atcatttcaa ctcgttcaaa
    17521 aatttttcaa aaattgaata ttgatgtaga gagtatttcg gtatcggaat tgcttcattt
    17581 gattgagcag tatcctagtc ttttgcgtcg tccaattatt attgatgcca agcgtatgca
    17641 aatcggtttt aatgaagatg agattcgtgc ttttctccct cgtagttatc gtaagcaaga
    17701 actaaaagaa gcaagaatga gagctggtat tagttaatga acaaacagta tagttaccca
    17761 ctagatttgt cgtggagcac tgaagaactt gcttcagtgc tttctttttt taatgatgtt
    17821 gaagctgcct atgaaggcaa agtagaggct aaaaagttac tggactccta taagggattc
    17881 aaagcggtcg tgccaagcaa gagcgaagag aaacgtttgg gacgagaatt tgaaacggtt
    17941 agtggctatt cactttaccg agcagttcag gctgccaaag aaaaagggga aggaaagatt
    18001 tctcttggaa agtaaatttg aatttgctaa agagcttgtt aagaaagcag gccagtacat
    18061 tcttgaccat atgcaggaag acttgcgtgt tgaaaccaag tcctctccaa cagatttggt
    18121 gaccagactg gacaaagaag ttcaggaact cttggttggt gagattttgt cccgttatcc
    18181 tgaggataag atttgtgctg aagaaggttg tctgcgagcc tcggttcaag agggcaaggt
    18241 ttgggtcatt gatcccattg atggtaccaa taattttgta gcccagcagg aagattttgc
    18301 tgttatgatg gcttattttg aaaatggtca gggacagttt ggtctgattt atgatgtggt
    18361 caaaggggat tgttaccacg gtggtgggga atttccagtt tgtctaaatg ataggcccct
    18421 agctcctttt aaaactaaac cacttggaga ttttctcatt gcagggaata gtggtatgct
    18481 ggaaaccaat gaatgggggc tggctgattt gagccgagcg gttcttggtg ttcgtgtcta
    18541 tggaagtgcg gccattagtt ttgccaagat tttgtcaggg cgtttgttga cctatctcac
    18601 ttatctgcaa ccatgggatt atgccgcagc tagtatttta ggggaaagtc tgggctatcg
    18661 ggttgtgacc ctttttggtg aagctcctga ttttcaaacc agacagcctg tcatgatggt
    18721 gcctcttgag atgcaggagg aaattcagtc ctatatttac gaaaggaaaa gaacttaaat
    18781 gcaatttcca gaaggatttg ttgaaaaata taaagaaata ctaggagatg aggcaagaga
    18841 ttttcttgcc tcttttgagg aggaagcggt ttcggccttt cgggtcaatc ccttaaaaga
    18901 agagcaactt tccttttctg atgccattac tcaaacccct tggggccact atgggaaggt
    18961 ttcagggaaa tcgcctgagc atgctacagg tttagtttat tcgcaagaac ctgctgctca
    19021 aatggtggct caagtagccc aacccagtcc tggtatgaag gtcttggact tggctgctgc
    19081 accggggggc aaatcaactc aactggcagc ctatctagca ggggaggggc tacttgtttc
    19141 caatgaaatt tcaagcaaac gggctaagat tttggttgaa aacatggagc gttttggagc
    19201 gacaaatgtc gtggtgacca atgaatctgc cgaccgcttg gtcaaggtct ttaaaggcta
    19261 ttttgactta atcgttcttg atgccccttg ctctggtgaa ggaatgtttc gtaagcaacc
    19321 tgatgctatg gactattgga gcttagatta tccgagtcaa tgtgctagct tgcaaagaga
    19381 aattctggag gatgcagtga ccatgttagc tgaaggtggt cgtctggttt attcgacctg
    19441 tacctgggca cccgaggaaa acgaagagat tgtcaattgg ttgctggaag agtatgattt
    19501 tgacttgttg ccagtagagc atatcaatgg aatggtagct ggtattgacc tgccagaaac
    19561 ggctcggatg taccctcatc agtttaaggg agagggtcag tttgttgccc atctacagtt
    19621 taagggtaac aatccagctc ctaaatttaa ggcaagtaag agtaacctca gccgtgaaca
    19681 agttgccttg tggcaggaat ttgcccaaaa ccatttgaag gtcaatctac cgggtatctt
    19741 gcagattttt ggagaccagc tttatctctt gccagaactt ttgccagatt tagggaagct
    19801 caagattgct cgcaatggac tgcatctggg tacttttaag aagaaacgct ttgagcccag
    19861 tttcgctctt ggtttagcct tgaaaccgag tcaggtcgaa cagtcggttg aaattggcca
    19921 agaagcgttt gtcaagtatg cggctggaga aaccgttcag ctggcagaaa gtctgccaaa
    19981 tggttggtac caagttttgg ttaaaggcaa tggcttgggc tttgcaaagg ttactggaaa
    20041 tgttttgaaa aattattttc caaaaggcct cagattcaaa tgaaaatgct agtcaaatat
    20101 cttattctat gttatagtga aagtatggat ttttttagta ggatgattct tgatatcttg
    20161 attgccatca catgtagttt tactactcga tgaaaatcaa agagcaaact aggaagctag
    20221 ccatagatag ctcaaaacac tgctttgaag agattttcaa agagtacaag aagtttagtt
    20281 attagcgttc ttaccgcttg taaactagat ttctcataaa atagaatctt ttccttttag
    20341 ttgtaaacta gtctgggaga gtagagaggt ttgagatacc tttctagctt ttggattatc
    20401 atctaagaag agtaatttcc cttgcattaa aaaggggaaa aagagacacg aaatgactat
    20461 aatgggtgac aatgggggaa gggatagaca agagatttta tccacatatg aaaaaaggag
    20521 gttaggaaag agtaatatag cctatattat ataaataatc aattgcgcag aaatttggta
    20581 agaattcatg cgtcaactca taaagaacta cttaaaaaat tcacagtatt cataattatt
    20641 ttcgaggaga aaaacagtga aaaaaagaaa aaagcttgct ctgtctctta tcgctttttg
    20701 gctgacggct tgtttagtag gctgtgctag ctggattgat cgtggagaat ccataacggc
    20761 tgttggctca actgccttgc aacccttggt tgaagtagcg gcagatgaat ttggcacgat
    20821 ccatgttgga aaaacggtca atgtccaagg gggaggttct ggtacaggct tgtcccaggt
    20881 tcagtctggg gcagttgata taggaaactc agatgtattt gctgaggaaa aagacggaat
    20941 tgatgcttct gctcttgttg accacaaggt cgcggtagct ggcttggctc tgattgtcaa
    21001 taaggaggtt gatgttgata acctaacgac agagcaactt cgtcaaatct tcataggtga
    21061 ggtaaccaat tggaaagagg ttggtggtaa ggacttaccc atctctgtta tcaatcgggc
    21121 agccggctct ggctctcgtg ctacctttga tactgtcatt atggaaggtc agtctgccat
    21181 gcaaagtcag gagcaggatt caaatggagc ggtaaaatca atcgtatcaa aaagtccagg
    21241 agctatctct tatttatctc ttacctatat agatgattcg gtcaaaagca tgaagttgaa
    21301 tggctatgac ttaagtccag aaaatataag tagcaataat tggcccttgt ggtcttatga
    21361 gcatatgtat acattggggc agcccaatga gttggctgca gaatttctca attttgttct
    21421 ctcggatgag acccaagaag ggattgtcaa aggattgaag tatattccga ttaaggaaat
    21481 gaaggttgaa aaagatgctg ccggaactgt gacagtgttg gaagggagac aataatgaat
    21541 caagaagaat tagctaagaa aatgttgctt ccatcaaaga attctcgtct ggagaaatta
    21601 ggaaaaggtt tgacctttgc ctgtctttct ttgatagtca tccttgtggc catgattttg
    21661 gttttcgtag cgcaaaaagg cttgtcgacc ttctttgtca atggtgtgaa tatctttgac
    21721 tttcttttgg gaggaacttg gaatccttct agtaaagaat ttggtgccct tcctatgatt
    21781 ttgggttcct ttatcgttac cattctctca gcccttatcg caacaccctt tgctattggt
    21841 gcagcagttt ttatgaccga agtatcacca aaaggggcga agattttgca accagctatt
    21901 gaactcctgg ttgggattcc ttcagtagtg tacggattta ttggcttgca agtcgtcgtt
    21961 ccctttgttc gcagtgtctt tggtgggact ggttttggga ttttgtcagg gatttccgtc
    22021 ctctttgtca tgattttgcc gaccgtaacc tttatgacaa cggatagctt gcgtgcggtt
    22081 cctcgttatt atcgtgaggc tagtttcgct atgggagcca ctcgctggca gactatctgg
    22141 cgtgtgatct tgaaggcggc ccgttctggt attttcactg cagtggtctt tgggatggcg
    22201 cgtgcctttg gtgaggctct agctatccag atggttgtcg gaaactcagc tgttatccca
    22261 acttccttga ccacaccagc tgcaacttta acttctatat taactatggg aattgggaac
    22321 actgtcatgg gaactgtaaa taataatgtt ctctggtcac tggccttggt actgctcttg
    22381 atgagcttag tttttaacag tgtgattaaa ttgattacga aagaaagagg aaagaaaaat
    22441 tatgcgcgct aagaaattag ataaacttgc aacagctgtc ctctatacga ttgctagcat
    22501 cattgtgaca atcttggctt ccttgattct ctatatcttg gttcggggct tgccccatat
    22561 ctcttggtct ttcttgactg gaaggtcttc tgcttttcaa gcaggtggtg ggattggcat
    22621 tcagctttac aattcctttt tcctattggt cattaccttg attatttctg tacctctttc
    22681 tatgggagct gggatttact tggctgaata tgctaaaaaa ggtcctgtta ccaactttgt
    22741 gcgaacttgt attgaaatct tgtcctcttt accatcagtg gtggtgggtc tctttggtta
    22801 cttgatcttt gtagtccagt ttgagtatgg attttcaatc atttcaggtg ctttggcctt
    22861 gacagtcttt aacttgcctc agatgacgcg taatgtagaa gatagtttga aacacgttca
    22921 ccatacccaa cgtgaggctg gtctggctct tgggatttct cgctgggaga cagtggttca
    22981 tgttgttatt ccagaagcgc ttccaggtat tgtaacgggt gtcgtcttgg catctggtcg
    23041 tatctttggc gaagctgcag ctctgatcta tacagcaggg caatcggcgc cagctcttga
    23101 ctggtctaac tggaatatcc tcagtgtgac tagccccatc tctatcttcc gtcaagcaga
    23161 aaccttggct gtccatatct ggaaagtcaa tagtgaaggc actattccag atggaaccat
    23221 tgtatcagca ggttctgccg ctgtgctcct gatctttatc ctgattttta actttggagc
    23281 tcgtaagttc ggaagctatc tacacaagaa attaaccgct gcctaaagga gaagccatgt
    23341 caacatataa ctgggatgag aagcatatcc ttacctttcc tgaagaaaaa gtagcccttt
    23401 ctactaagga tgtccatgtt tattatggta aaaatgaatc cattaagggg attgatatgc
    23461 aatttgaaag aaataaaatt acagctttga ttggtccgtc gggatcgggg aaatctacct
    23521 acttacgcag tctcaatcgc atgaatgata ccattgatat tgctaaagta actgggcaga
    23581 ttctctatcg tggaattgat gtcaaccgtc cagaaatcaa cgtttatgaa atgcgtaaac
    23641 acattggaat ggtttttcaa cgccccaatc catttgctaa gtcaatttac cgtaatatta
    23701 cctttgcgca tgaacgtgct ggagttaagg ataagcaagt cctagatgaa atcgtagaaa
    23761 cctcccttcg tcaggctgcc ctctgggatc aggttaaaga cgatctccac aagtcagcct
    23821 tgaccttatc aggtggtcag caacaacgtc tctgtatcgc tcgtgccatc tctgttaagc
    23881 cagatatcct cttaatggat gagccagcct cagccttgga tccgattgcg accatgcaac
    23941 tagaagagac catgtttgag ctcaagaaaa actttaccat catcattgta acgcataata
    24001 tgcagcaggc tgctcgtgca agtgactata caggcttctt ttacttgggt gatttgattg
    24061 agtatgacaa gactgcaact attttccaaa atgccaagct acagtccacc aatgactatg
    24121 tatctggtca ctttggttag aaaggaaacc gtatgacaga tgcgatttta caggtatcag
    24181 acctgtccgt ttattataat aaaaagaagg ctttgaatag tgtttcccta tctttccaac
    24241 ctaaggaaat tacagccttg attggtccat ctggatcagg gaagtcaacc ctcctcaagt
    24301 ctctcaaccg catgggagat ctcaatccag aggtgaccac aactggatcc gtggtgtaca
    24361 atggtcacaa catctacagt ccgcgtacag atacggttga attacgtaag gaaatcggaa
    24421 tggttttcca acaacctaat cctttcccta tgactatcta tgagaatgtt gtctacgggc
    24481 ttcgtatcaa tggaattaag gataagcagg ttctggatga agccgtagaa aaagccttgc
    24541 aaggtgcctc tatctgggat gaggtcaagg atcgtctata tgattcagct attggattgt
    24601 caggtggtca acagcagcgt gtctgcgtgg cccgtgtctt ggcaactagt cctaaaatca
    24661 tcctcttgga tgagccaact tcggctttgg atccgatttc agctggtaag attgaggaaa
    24721 ccttgtatgg tctaaaagac aagtacacca tgcttctggt aacccgttcc atgcagcaag
    24781 cttcacgtat ctctgataag acaggatttt tcctagatgg agatttgatt gaatttaatg
    24841 ataccaagca gatgttcctt gatccccaac acaaggaaac ggaagactat attacaggaa
    24901 aatttggata aggagatgaa agatgttacg atctcaattt gaagaagatt tagagaaatt
    24961 acataaccag ttctacgcta tgggacaaga agtgctctca caaatcaatc gtacggtacg
    25021 tgcttttgtc acgcatgacc gtgacctggc aaaagaggtc atagaagatg atgcagaagt
    25081 aaatgaatac gaagtgaaac tggaaaagaa atcatttgaa atgatcgcac tccaacaacc
    25141 agtctctcaa gatttgcgta cagtcttgac tgtccttaag gctgtatcag atgtggagcg
    25201 tatgggggat cacgctgtag ccattgccca ggcaaccatc cgtatgaagg gggaagagcg
    25261 catcccagct gtagaggaag aaattaaaaa aatgggacgt gaagttaaaa gcgttgttga
    25321 agcagcactt gatctttatc ttaatggttc tgttgacgac gcataccggg tggcctccat
    25381 ggatgagcaa attaaccact attttgaaac tatccgtgac cttgcgactg aagagattaa
    25441 gaaaaatcca gaagccattg ttacgggtcg tgattatttc caagttattt cctacttgga
    25501 gcgtatcggt gactatgcta aaaatatctg tgaatgggtt gtctactttg aaacaggtaa
    25561 gattgtcgaa ctataaaata gtttaattct gtataaaaag gagcttgaaa tcaactgatg
    25621 gctccttttt ttgaacgaaa aaatattttt gagataaaaa tttaaaaaac acttgacaag
    25681 taacttggat atcgttataa ttatacaaaa ttaacagaga ggttgtttat ttatgaaatc
    25741 aaaaaaatgg atatttgttt tatgtaattt tcttgcaagt ttcttcttag tagcttgcca
    25801 gtcaggttct aatggttctc agtcagctgt tgaggccatt aagcaaaagg ggaaattagt
    25861 tgtggcaacc agtcctgact atgcaccctt tgaatttcaa tcattggttg acggaaagaa
    25921 tcaggtagtc ggtgcagaca tcgacatggc tcaggctatc gctgatgaac ttggggttaa
    25981 gttggaaatc tcaagcatga gttttgacaa tgttttgacc agtcttcaaa ctggtaaggc
    26041 tgacctagca gttgcaggaa ttagtgctac tgacgagaga aaagaagtct ttgatttttc
    26101 aatcccatac tatgaaaaca agattagttt cttggttcgt aaggctgatg tggaaaaata
    26161 caaggattta actagcctag aaagtgctaa tattgcagcc caaaaaggga ctgttccaga
    26221 atcaatggtc aaggaacaat tgccaaaagc tcaattaact tccctaacta atatgggtga
    26281 agcagtcaat gaattgcagg ctggaaaagt agatgctgtt catatggatg agcctgttgc
    26341 acttagttat gctgctaaaa acgctggctt agctgtcgca actgtcagct tgaagatgaa
    26401 ggacggcgac gccaatgccg ttgctcttag aaaaaatagt gatgatttga aagaagtggt
    26461 agacaaggtc atccaaaaac ttaaggatga aggaacttac caaagctatc ttgaaaaagc
    26521 agcaagtcta actgaagttg aagaataaga aaaagcagag ttggatgtca ttccaattct
    26581 gcttttaaat agtttaaaac attttccaga ttgtctaggg acaccttggc aaattgataa
    26641 ggacaggtgc ttaaataggc ctcttcaaag aagtccaagc ccagttgact gtgtttgaga
    26701 ctggcgattt taggatactg tctcaggtct agcaataaac catcgtgtag gggataatga
    26761 ggaaggggac aaggtgtttt agttatcctt tcctcgattt gtttttggta agattcatga
    26821 ttggtcaagc gagccaaacg atttttttca aacaattgac tgtcaatata gagtgacagg
    26881 gccttttgca taatgaggtt gctgtcgtag tctaggatat ttttgtaggc cacaaatgct
    26941 tctttgatag catttggaag aatgagtgct gtaatacgaa gggcaggaaa aaggctggtc
    27001 gagaaggact tgatataaat gacacgctcc tctgtatcaa gatagtggaa ggtttggccc
    27061 ttcttggagt ccaaatcacc cagataatcg tcctctacga tatagacatc atacttggca
    27121 gctaagttaa gaatagatcg tttgtcctgc tcagaatagg aatgtcccag aggatagtga
    27181 aatcggggaa tggtgtagaa aaatttaatt tttcctgttt tgaagtggcc ttccagctcc
    27241 tccaagtcaa tcccatcaat gcctcgttca atcgtttgat agtccagccc ctgtgcaatc
    27301 aagaggcgat tcatccgatg gtaggttggc tgttccacca agatttcctt ggcttgtcta
    27361 ggaaaggata tttgagagag gataaacaag gcttgttggg ttccagaagt cagtactagt
    27421 tggttagcct tgcagtagag agcttgctca aagaggagtt tgtgaatgga ctgtcttagg
    27481 tcttctaatc cttcttgatt gtcatagtag ttgaagaggt agttttctcg gccaatcaag
    27541 gtttcattga cacagagtcg gaaatcgtca taggcactgg catgttcgtc ggtaacctcg
    27601 atttctaggt cttgatgttg cccttgttct aatacatagt agccactctg aggcttggca
    27661 tagaggtatt gttcgtgccg taattccagc agggctcgtt gaatggtgtc cttgctgcag
    27721 tgaaagtcaa ggctcagttg acggatagaa ggcaggcgac tacccgtcgg aaatcgttca
    27781 gactcgatac catttttcag ataggaaacg acctctttgt acttgctttg tttcttcatt
    27841 ccagacctcc cttgattttg ttacattgta cccttttttt tccttcttgg caatgtctag
    27901 agcgtttctc tcgttcacat ctaggggcaa atgtggtata cttaggagta agatttatag
    27961 aataacagac aagaaagtga atggataaga acgtgcagga accagtgaaa ttatttcaat
    28021 acaatactct tggagccttg atggctggcc tttatggtgg tactatgaca gtaggagaat
    28081 tgctagaaca tggtgacctt ggtttgggaa ccttggattc cattgatggg gaattgattg
    28141 tcttggatgg caaggcttat caggccaaag ggtcaggaga ccagccagaa attgtggaag
    28201 tgtcaccaga tgcccttatt ccttacgctg cagtggtacc gcatcaggca gaggtcattt
    28261 tccgccagcg ctttgagatg acagacaagg aattgaaaga acgaattgag tcttattatg
    28321 atggggaaaa tcttttccgt tctatcaaga ttcgggggga attttcacat atgcatgtgc
    28381 gtatgattcc taagtcaaca cccgatacca agtttgctga tgtcgcaacc catcaaccgg
    28441 aatatagtcg tgacaatgtt gcggggacta ttgttggttt ctggacgcct gagattttcc
    28501 atggggtcag tgtggcaggc taccatctgc acttcatatc agatgatttg accttcggtg
    28561 gacatgtcat ggattttgtc atcaaggaag gcattatcga ggtgggagca gttgaccagt
    28621 tggaccaacg tttcccagtc caagaccgtc aatacttgtt tgctaagttc aatgttgacg
    28681 agatgaaaaa agatattgaa aaggcagaat aggagaagaa aatgaccatt catatcatta
    28741 ttaccatgtt gctgttgcta gcttttctga taggaagcat ttggtttgcc aaaaagaaat
    28801 accagattaa tctagctgtc ttgggcttgg gtgcagtcgc tttctttgtc tcttcgcaga
    28861 ttttggaaaa actggtgcat atcttgattt tgcatcctca aaaaagacgg tagtattgcc
    28921 ctcttgcaag atcacccgct tgtctatatt atctatggcc tagctatggc agcatttttt
    28981 gaggaaacgg ctcgtcttgt tttcttcaaa tggttggaga aaaagagaag tttggaaaag
    29041 gcagacgcct tggcctatgg actggggcat ggtggcttgg agttgatttt tctaggcctt
    29101 actagtttac tcaatcttta cattgttctt tcggcagttc aaactcagaa tccacaggtt
    29161 atgcaattac tgtctgaaaa tatgttaaaa accattcagt cactttcggt ctggcagatt
    29221 tatttgcttg gttttgagcg aatcttggcg cttggtttcc aattactttt gacagtttgg
    29281 gtttaccaag ctgttcgcca gaagaaatgg atttatctcc tagcagccta tggcttgcat
    29341 gccttctttg atctggcacc atctctttcc caagtaggct ggttgacaaa tccagtcttg
    29401 gttgaagtga ttctagcact ggagctcgtt ctggtcgcct atggaaccaa ggaaatcttt
    29461 tgtaaaaaat cataaaaagg gggaaacctc tttttcttat gcaaaatcca aacaaggtat
    29521 ttttatggtc gtcaaatgtc tctaaaaatg gtataatgga atgaattttg taaaaggaag
    29581 agtgacatgt ctgtaagaga aaaaatgctt gaaatcttag aaggaattga tatccgtttt
    29641 caggaaccct tgcatagcta tagttataca aaagtaggtg gagaggctga ttatttggtc
    29701 tttccacgaa atcgttttga gttggctcgc gttgtgaaat ttgccaacca agaaaatatc
    29761 ccttggatgg ttcttggcaa tgcaagcaat atcatcgttc gtgatggtgg gattcgtgga
    29821 tttgtcatct tgtgtgacaa gctcaataac gtttctgttg atggctatac cattgaagca
    29881 gaagctgggg ctaacttgat tgaaacaact cgcattgccc tccgtcatag tttaactggc
    29941 tttgagtttg cttgtggtat tccaggaagc gttggcggtg ctgtctttat gaatgcgggt
    30001 gcctatggtg gcgagattgc tcacatcttg cagtcttgta aggtcttgac caaggatgga
    30061 gaaatcgaaa ccctgtctgc taaagacttg gcttttggtt accgccattc agctattcag
    30121 gagtctggtg cagttgtctt gtcagttaaa tttgccctag ctccaggaac ccatcaggtt
    30181 atcaagcagg aaatggaccg cttgacgcac ctacgtgaac tcaagcaacc tttggaatac
    30241 ccatcttgtg gctcggtctt taagcgtcca gtcgggcatt ttgcaggtca gttaatttca
    30301 gaagctggct tgaaaggcta tcgtatcggt ggcgtagaag tgtcagaaaa gcatgcagga
    30361 tttatgatca atgtcgcaga tggaacggcc aaagactacg aggacttgat ccaatcggtt
    30421 atcgaaaaag tcaaggaaca ctcaggtatt acgcttgaaa gagaagtccg gatcttgggt
    30481 gaaagcctat cggtagcgaa gatgtatgca ggtggtttta ctccctgcaa gaggtagtgg
    30541 ggacctgaca gagccccgat cggttaatct atgaaaaaga aggaatttat gccaattgaa
    30601 aaaaccaatt atcgaattca aaaacgtctc taaagttttt gaagacagca acaccaaggt
    30661 tctcaaagac atcaactttg agttggaaga agggaaattc tacacccttc taggtgcatc
    30721 tggttcgggg aaatcaacta tcctaaacat tattgcaggt ttactggatg cgacgacagg
    30781 agatatcatg ctagacggtg ttcgtatcaa tgatattcca accaacaagc gcgacgtaca
    30841 taccgtcttc caatcctatg ccttgttccc acatatgaat gtgtttgaaa atgttgcctt
    30901 tccacttcgc ttgcgtaaaa ttgataagaa agaaatcgag cagcgtgtag cggaagttct
    30961 caagatggtt cagttggaag gttatgaaaa acgttccatc cgcaaacttt ctggaggaca
    31021 acgtcagcgt gtggccatcg cccgtgctat catcaaccaa ccccgtgtgg tcttgttgga
    31081 cgagccttta tcagcgctgg acttgaaatt gagaacagac atgcagtacg aattgcgtga
    31141 attacaacaa cgattgggca ttacctttgt ctttgtcact cacgatcagg aagaagctct
    31201 tgccatgagt gactggattt tcgttatgaa tgatggcgag attgtccagt ctggaacccc
    31261 tgtggacatc tacgatgagc caatcaacca ctttgttgcc acctttatcg gggagtcaaa
    31321 catcttgcca ggtaccatga ttgaggacta cttggtcgaa tttaacggca aacgctttga
    31381 agcggttgat ggtgggatga agccaaatga acctgttgag gtcgttattc gtccagagga
    31441 cttgcgcatt acccttcctg aagaaggcaa actccaagtt aaggtcgaca cccagctctt
    31501 ccgtggagtt cattatgaaa ttatcgccta tgacgaactt ggaaatgaat ggatgatcca
    31561 ctcaacccgt aaggccatcg tgggtgagga aatcggtctg gactttgaat cagaagacat
    31621 ccacatcatg cgtctcaatg aaaccgaaga agagttcgat gctcgtatcg aagaatacgt
    31681 ggaaatcgaa gagcaagaag caggtctgat caatgcgatc gaggaggaaa gagatgaaga
    31741 aaacaagctc taaactcttt gtagtgccct acatgctttg gattgccctc tttgtattgg
    31801 cacccttggt cttgattttc ggacaatcct ttttcaacat tgaaggccag tttagtttag
    31861 aaaattataa atcttacttt gcgtcacaaa acttgaccta cctcaaaatg agtttcaact
    31921 cagtgcttta tgcaggcatt gtgacctttg tgaccttgct tatcagctat ccaacagccc
    31981 tctttttgac ccgtctcaag caccgtcaac tctggctcat gctgattatc cttcctacct
    32041 ggatcaattt gctccttaaa gcctatgctt ttatcgggat ttttggtcaa aatggctcta
    32101 ttaaccaatt cttggaattt atcggaattg gttcacaaca gttgcttttt accgattttt
    32161 cctttatctt tgtcgcaagc tacatcgagc tcccctttat gattttgccg attttcaatg
    32221 tcttagacga tatggataat aatctcatca atgctagtta tgaccttggt gcaactaagt
    32281 gggagacctt ccgtcatgtc atcttccctc tatctatgaa cggtgtgcga agtggggttc
    32341 agtcggtctt tatcccaagt ttgagtctct tcatgctgac ccgtttgatt ggtgggaacc
    32401 gcgttatcac cttggggacg gctattgagc agaattttct aaccaatgac aactatggta
    32461 tgggttcaac catcggtgtg attctcatcc tgaccatgtt catcaccatg tgggtgacta
    32521 aggaaaggag agaacgatga aaaaatttgc caacctttat ctgggactgg tctttctggt
    32581 cctctacctg cctatctttt acttgattgg ctatgccttt aatgctggtg atgatatgaa
    32641 tagctttaca ggttttagct ggactcactt tgaaaccatg tttggagatg ggagactcat
    32701 gctgattttg gctcagacat ttttcttggc cttcctatca gctttgatag cgaccattat
    32761 cgggactttt ggtgccattt acatctacca gtctcgtaag aaataccaag aagcctttct
    32821 atcactcaat aatatcctca tggttgcgcc tgacgttatg attggtgcta gcttcttgat
    32881 tctctttacc caactcaagt tttcacttgg ctttttgacc gttctatcta gtcacgtggc
    32941 cttctccatt cctatcgtgg tcttgatggt cttgcctcga ctcaaggaaa tgaatggcga
    33001 catgattcat gcggcctatg acttgggagc tagtcaattt cagatgttca aggaaatcat
    33061 gcttccttac ctgactccgt ctatcattac tggttatttc atggccttca cctattcgtt
    33121 agatgacttt gccgtgacct tctttgtaac aggaaatggc ttttcaaccc tatcagtcga
    33181 gatttactct cgtgctcgca aggggatttc cttagaaatc aatgccctgt ctgctctagt
    33241 ctttctcttt agtattatcc tagttgtagg ttattacttt atctctcgtg agaaggagga
    33301 gcaagcatga aaaaaatcta ttcattttta gcaggaattg cagcgattat ccttgtcttg
    33361 tggggaattg cgactcattt agatagtaaa atcaatagtc gagatagtca aaaattggtt
    33421 atctataact ggggagacta tatcgatcct gaactcttga ctcagtttac agaagaaaca
    33481 ggaattcaag ttcagtacga gacttttgac tccaacgaag ccatgtacac taagataaag
    33541 cagggtggaa cgacctacga tattgccatt ccaagtgaat acatgattaa caagatgaag
    33601 gacgaagacc tcttggttcc gcttgattat tcaaaaattg aaggaatcga aaatatcgga
    33661 ccagagtttc tcaaccagtc ctttgaccca ggtaataaat tctccatccc ttacttctgg
    33721 ggaaccttag gaattgtcta caacgaaacc atggtagatg aagcgcctga gcattgggat
    33781 gacctttgga agccggagta taagaattct atcatgctct ttgatggggc gcgtgaggtg
    33841 ctgggactag gactcaattc cctcggctac agtctcaact ccaaggatct gcagcagtta
    33901 gaagagacag tggataagct ctacaaactg actccaaata tcaaggctat cgttgcggac
    33961 gagatgaagg gctatatgat tcagaataat gttgcaatcg gcgtgacctt ctctggtgaa
    34021 gccagccaaa tgttagaaaa aaatgaaaat ctacgttatg tggtaccgac agaggccagc
    34081 aatctttggt ttgacaatat ggtcattccc aaaacagtta aaaaccaaaa ctcagcctat
    34141 gcctttatca actttatgtt gaaacctgaa aatgctctcc aaaatgcgga gtatgtcggc
    34201 tattcaacac caaacctacc agcgaaggaa ttgctcccag aggaaacaaa ggaagataag
    34261 gccttctatc ccgatgttga aaccatgaaa cacctagaag tttatgagaa atttgaccat
    34321 aaatggacag ggaaatatag cgacctcttc ctacagttta aaatgtatcg gaagtaggag
    34381 ataaacgtaa gaagacgaat cagtcaagct ggttcgtttt taaggaatag aagtcagttt
    34441 ttagagccct atctttttct attctagttg tttatttgtt tatttgctta tttgcttgcc
    34501 tagtagtata ctaagcctat actcttcaaa ccacgtcagc gttgccttgc cgtactcaag
    34561 tacagcttga ggctagcttc ctagtttgct ttttgatttt tattgagtat taaccttaca
    34621 gaaagcggca acaaataatg aaaatgtcta cttttttcaa aaaaagtttc tggccaacct
    34681 ttatgattgt taaccaaact gctatactat tccatttaaa ggatggcttg gatcgacaat
    34741 acctaacaac tgagtccata tattgggtga taggcacctt tatatttgga aatattctag
    34801 tagctgtgtt tagtaatatg aaaatttggg ataaaaagaa aaacggcagt aagaaaaaat
    34861 atatcctgaa aaagtaatca gagatgtagg gaattggtct aattcaacgg agatcatttc
    34921 cagttgacgc aagcttaaaa aaacgttata ataagaaagt tgagaattga ttttcacttg
    34981 tcttagtcca gagaaatggc ggtgctgcga gccatctaag ctaggaagtc atgctgctca
    35041 atcatacaat tgcataagaa caagagaatg acaagttcat tgaatgaagg tggtaccgcg
    35101 gtttttcgcc cttcgtgata tgagcttgtc ttttgatttt tggaggtgtt gatgaaaaca
    35161 tttcttgtca aacaaaagtt tcgtcttgga ggcgaacgct tcgctatcaa ggatgacagg
    35221 ggagaaattg cctatcaggt ggagggatca ttttttaaga ttcctaaaac ctttaccatc
    35281 tatgatgcgg ctggtgaaca agtcagtgag attagtaaag aaatcttgac cttgcttcct
    35341 cgttttgaga ttcagcttcg ggatggctcg agttttgtca ttcgtaagaa gttgaccttc
    35401 tggcgagata agtatgagtt tgataatcta ggtcttcgta tcgagggcaa tatctgggat
    35461 ttgaatttca aattgctgga tgatcgcgat cagttgattg cggaaattaa gaaggaactc
    35521 ttccatctga cctctaccta taccgtaacg gttcttgaag acgcttatgc agacctagtc
    35581 atttccctct gtgtcgcgat tgactatgtg gaaatgctgg aaagccaatc acattaaaca
    35641 agtaaataag gagacaatat gaaacaacta tctagtgcac aagtacgcca aatgtggctt
    35701 gatttctggg cgaccaaagg tcactcagta gaaccatcag taagtttggt tcctgtaaat
    35761 gacccaactc ttttgtggat caactctggg gtagcaaccc ttaagaaata ctttgacggg
    35821 accattatcc ctgaaaatcc acgtattacc aatgcccaaa aggctatccg taccaacgac
    35881 atcgaaaacg tagggaagac tgcgcgtcac cataccatgt ttgaaatgtt ggggaacttc
    35941 tctatcgggg attacttccg tgacgaagct atcacttggg cttatgagct tttgacaagc
    36001 cctgaatggt ttgatttccc tgctgaaaaa ctttacatga cctactatcc agacgataaa
    36061 gattcttaca accgctggat tgaagtggga gtggatccaa gtcacttgat tccaattgag
    36121 gacaacttct gggaaatcgg tgcgggacct tctggaccag atacagaaat cttctttgac
    36181 cgtggggaag cctttgaccc agaaaatatc ggtcttcgcc tgcttgcaga agatattgaa
    36241 aacgaccgtt atattgaaat ctggaacatc gttttgtcac aatttaacgc agaccctgct
    36301 gttcctcgta gcgaatacaa ggaattgcca cataagaaca ttgatacggg cgctggtttg
    36361 gagcgtttgg tggctgttat ccaaggggct aagaccaact ttgaaacgga cctctttatg
    36421 ccgattatcc gtgaagtcga gaaattgtct ggtaaggttt atgaccaaga tggcgacaac
    36481 atgagcttca aggttatcgc agaccacatt cgttctcttt catttgctat cggtgatggt
    36541 gcccttccag gaaatgaagg tcgtggttat gttcttcgtc gtcttctccg tcgtgcttct
    36601 atgcatggtc aaaaattggg tatcaacgag cctttccttt acaaacttgt tccaactgtt
    36661 ggaaacatca tggaaagcta ctacccagaa gtgcttgaga aacgtgactt tattgagaaa
    36721 atcgttaaga gcgaagaaga atcatttgcc cgtacccttc actcaggtca acactttgcc
    36781 caaggcattg tggcagactt gaaagaaaaa ggtcaatctg tcattgctgg tcaagatgtc
    36841 tttaaactct atgatacata cggattccca gttgaattga ctgaagaaat tgctgaagaa
    36901 gctggtatga ctgtagaccg tgaaggtttt gaagcagcca tgaaagaaca gcaagaacgc
    36961 gcgcgtgcgt cagctgtcaa gggtggctca atgggtatgc aaaatgaaac tcttcaaaac
    37021 atcactgtag aaagtgtctt caactacaat gctagccaat tgtcttctaa attggtagct
    37081 atcgttgctg acaatgcaga agtaggagct gtttcagaag gaactgcctc tcttatcttt
    37141 gcggaaacgt cattttatgc tgaaatgggt ggacaggtag ctgactacgg acaaatcttg
    37201 gatgagtcag gtaaggttgt ggctactgtg accaatgttc agaaagcccc aaatggtcaa
    37261 gcccttcata cagttgaagt ccttgcaccg cttgccttga accaagaata taccttggca
    37321 attgatagca atcgccgtca ccgtgtcatg aaaaaccaca ctgcgactca tttgcttcac
    37381 gctgcccttc acaatatcct tggaaaccac gcaacacagg caggatctct taacgaagtt
    37441 gaattccttc gctttgactt tacccacttc caagcagtaa ctgctgagga acttcgtgcg
    37501 attgaacagc aagttaacga gaaaatttgg gaagcacttg aagtgaagac agttgaaacg
    37561 gatattgaca ctgctaaaga aatgggagct atggccctct ttggtgagaa atacggcaag
    37621 gaagttcgtg tcgtgactat cggtgactac tctattgaac tttgtggtgg tactcatgtt
    37681 ggcaacactt ctgagattgg tctcttcaaa attgtcaaag aagaaggaat cggttcagga
    37741 actcgccgta tcttggcagt gactggtaag gaagcctttg aagcctatcg tgaacaagag
    37801 gatgctctta aagctgtcgc agcaaccttg aaagcacctc aagtcaagga agtacctcac
    37861 aaggtagaag gacttcaaga acaacttcgt caacttcaaa aagaaaatgc tgagttgaaa
    37921 gaaaaagccg cagctgcagc cgcaggcgat atcttcaaag atgctaagga agtcaacggt
    37981 catcgttaca ttgctagtca attgtctgta tccgatgccg gtgcccttcg tacttttgca
    38041 gataactgga aacaaaaaga ctactctgat cttcttgtcc tagttgccgc tatcggtgac
    38101 aaagtcaatg tccttgtagc aagcaagaca aaagaccttc atgcaggaaa ccttgtcaaa
    38161 gaattagcac caatcatcga tggacgtggt ggtggtaaac cagacatggc catggcagga
    38221 ggaagaaacc aagctaagat ccaagaattg ttggatgcag tagcaggtaa attgtaatca
    38281 agtaaagatc tatccatttg ggtaggtctt tttgtgaata caaaaaagcc aaatccgctt
    38341 ggacctagct tggttattat gagctattag atggtattga ctgcccagac acttacggat
    38401 ctagctgaga cagggaattg tccataacct tcctcatcaa ttgtaacttg accttggtgg
    38461 ttaccaagta aatctacaaa ggtttgatta gtccattctt gaccgacaaa cattgacttg
    38521 ctgttttctt ggtcatttga gataaggact gcgattgggg attgattttc agcacctgaa
    38581 cgtacccaac cgatacagtt agcatggtca aagtagtcat tttgttctcc ataggccaag
    38641 tcttttcgga tggctaggag gcggtcaagg atttctttga aatcttcttg agcatactgg
    38701 cctgaaatcc catagtagtc tccgtaaaag acacatggaa ggccgtcttg gcgtaacaaa
    38761 atgagggcat aggctgctgg cttgaaccat tcttcaacgg tagactcaag ggcttgtcct
    38821 cgttgggtat cgtggttgtc gataaaagtc acagccttgt caggcttgag ttcaaccagg
    38881 ctatctgtga aaatgccacg aaggtcatag tttgcgccag cttgactggc ttcaaagaga
    38941 ttctggtgga gacgaacatc gacaaggtca aagtgttctt ccgttttttc gagatagtcc
    39001 agattggctt ccttgtctgg gttccaaaat tcaccaaaaa catagaaatc gtcaccgtat
    39061 ttttccttca tatcgcggat gaaattgcgc ataaagaaag agtcaatatg cttaacggca
    39121 tccaaacgga aaccagctac accagtcgtt tccatgaacc aatcagccca gtcatagatg
    39181 ttttggatga cttcaggatg tttaaagtct aggtcggcat acatgaggta gtcgtagttt
    39241 ccgttttcgt tatcgaccaa ttcctcgtta gcccagccct tgttgtctcc ttggattagg
    39301 taaatcccgg atttacggcg tttggcatca tagtctgtac ctgtgaagtg gtaccagtgc
    39361 cagtggaagt cattgtaggt atcttggcga ccatcgaagg taaaactagt ccagccattg
    39421 atggtgaagg gttctccaag ttcaactgta cggtctacag gatccacttc aataacctga
    39481 aaggcttccc tgtgatcagc agcagccttg tggttgagaa ctacatcggc cataggttga
    39541 attccctgcg ctttaagggc ttgaatggct tgaagatagt cttctttgaa accatacttg
    39601 gtgcggacag tccctttttg gttgaactct cctaagtcaa ataagtcata gaccccatag
    39661 ccgacatctt tttcgttggt tgccttgaag gctggtggca tccagacgtg actgatcccc
    39721 agatgagcta ggtgtggagc attttcagcc agacgcgtcc agtgttgacc gtcgtggggc
    39781 agataccatt caaagtattg catgagtgtt tgattttgca tgatgtttcc tcttacttgt
    39841 caatcttgtt ctttattcta tcataaagta tctctcggag caaacgtttg cgtaagatag
    39901 aaggaaacta ttttaactac ttaaaataaa gtattgattt ttttgtatca aagtgctagt
    39961 atagcgatat ataatacaga taaagatagg agtcatccca tgattgaatt tcaaaatgtt
    40021 agtaagttgt atggtgataa agaggccttg agtaatctca atttgcagat tgaaaatgga
    40081 gagattatgg gcttgattgg tcataatggg gctggaaaat cgaccaccat aaaatcccta
    40141 gtcagtatca tttcacccag cagtggtcgt attttggtag atggtcagga gttatcggaa
    40201 aatcgcttgg cgatcaaacg aaagattggc tacgtagcag actcgcctga cttattttta
    40261 cgtttaacgg ccaatgaatt ttgggaattg atcgcctcat cctatgatct gactagctct
    40321 gacttggaga ctagtctagc taggctattg aacgtttttg attttgctga aaatcgttat
    40381 caggttattg aaaccctttc tcatggaatg cgtcagaaag tttttgtcat cggggcactc
    40441 ttgtctgatc ctgatatttg ggtcttggac gaacccttga ctggtttgga tccccaggct
    40501 gcctttgatt tgaaacagat gatgaaggaa catgcacaaa aagggaagac ggtcttgttt
    40561 tcaactcatg tcctagaggt agccgagcaa gtctgtaatc ggattgccat tttgaaaaag
    40621 gggcatttga tctattgtgg tagtgtagag aacttgagga aagaccaccc agaccagtct
    40681 ttggaaagta tctaccttag tcttgctggt agaaaagagg aggttgcgga tgcgtctcaa
    40741 ggtcattaaa aaattagttg atatcaatat cctctattca tctcaagaag ctaatctggc
    40801 taatctacga aagaagcagg ctaagaatcc tgggaaaaaa gtaaatgttt ccgctagagt
    40861 cctaagttct tacatttttt ctagtctctt gatgcttttc atgtttataa atatagcctt
    40921 tcgttttcct tttgaggaaa tgccaagttt ttttagtacg atggttgcta ttttactggt
    40981 gctggccttt tcaacttctt tcactgcatt ttacaatgtc ttttatgaga gtaaggacct
    41041 ggcctcctat aggccctatg cctttaaaga atcagagatt ataatggcca aaggtctgtc
    41101 tgtcctcttg ccagctctag ctggaattgt accaatccta gcttattttc tggtcctcta
    41161 cattaggcta gcaccttctc tgtggttggg tttgcctttg atgctactgt ccttgacctt
    41221 attatttgtc tctgttactt tagtgatggt agtggcagta catttcttgg ctcagactag
    41281 ggtcttcaga aagtatcggt ctattttttc gaatgtgatg attgggatag gagttctcat
    41341 acctttaata tttatcttct ttcttcagtc gacttttgga agtattgttg acaaagttag
    41401 agacattcca tttctccttt atcctcttca tatcttttac aaaatagcag tggagccttt
    41461 ttcgacagaa gccttagtgg gtctgctcgc ttggatagga ctaactctct tcctgcttta
    41521 tctgaccaaa aagaaggtcc ttcctcgttt ttatgacgtg atcctgctta atagtgagga
    41581 taaggtcaaa aaagaacgtc gcagcaagga gagaatttca accactaaaa agggattttt
    41641 tcgcatggtt ttacgctacc acctcaccct cttgggacag gggactggcg tggttacagt
    41701 gctttttaca agtgctttct ttccttatct catgatgatc ggtctgattt ccaaaatccg
    41761 agattctcag atagttccag acattcatcc tccatactgg ttacccttgt tttttatagc
    41821 tctctttata gcagttgtca ataacaatat caccagcctg cattcaattg ccttgtcctt
    41881 ggagagggaa aatgttgatt ttcttaagag tttacccttt gactttgctc gttatgtgaa
    41941 agtgaaattt tggattatat atgctgtcca gtccttttta ccagttctga ctttgcttgg
    42001 tctttctcta tatctaggct tgcccatcat ttcgatgatt taccttattg tggcatggat
    42061 ccttgccagt gtcatccttt cttgccacca ttactttaag gacgttaaaa atctgtcaac
    42121 caattggagt agcattacgg acctggtgaa tcgttcaaat ggcatagtcg ccatagtttt
    42181 attgtttatt tatagtgcaa tcctgatggc ccttgtaatt gggagcatat tcttggttca
    42241 gtctctctcc actatccttg ccatcagctt gggagtagga gctcttatcc tcctgcttgc
    42301 tcttgctatt tttggctatc attattacct gtcacgcata ttggcagaaa tagaaaaaag
    42361 atgagctggt tggtcgcttg cttgataaat tcaattcgac aaacgctttt atagtttgtt
    42421 agaatgtagt tgtaaatgat taagattggt aatcaaaaat atagggagga atgttttgaa
    42481 taagaaatat aacatagttc tatttttgtt gtttatagtt tatttatttg gatatttttc
    42541 aatttcaaaa acgttaattc ctataatgtg tgtgttccaa gtattcttga tagaacatat
    42601 atttagaatt cgaaatagaa tgatgcagat aggtgaaatt ataattattg ttgcttctat
    42661 aatattattt attgatagta tattgagttt gtaacaaaag gcttctctat aaaatcaaat
    42721 tttccagata tctactgaag ctgatttatt tcttcatctt tcttctacta cctttgtcac
    42781 taaatttgac agacacatat tgctgataca acctctctac ctataatctc acagttaacc
    42841 tgaggctagt ttcatagttt gctatttgat tttcgttgat aaaaaaaatg ctcctccaag
    42901 acggaagagc attttttatt gtgattctta cacatttact tcctagtttt gcaggaagtc
    42961 tagtatacca ttttttaaaa gaagagtaaa aaagcaaggg tagtttcttt tttgagaatt
    43021 gtctaaaagt ttgatataat ggtagttatg aatagaataa gagtcagcaa aagggttgaa
    43081 aagaagcttg ctaaggggct agttttacta gaagccagtg atcttgagaa tgtcaatctt
    43141 aaggatcagg aagtagaggt gcagggtcag gaaggaaact ttcttgggac tgcctacctt
    43201 tctcagcaaa acaagggctt gggctggttt gtcagcaaag acaaggtggc cttcaatcaa
    43261 gctttctttg aaacgttgtt tagaaaagcc aaagaaaaga gaagcgccta ctatcaagat
    43321 gatttaacaa ctacctatcg tctctttaat caagagggag atggctttgg gggtctgaca
    43381 gtggaccttt atggcaacta cgccgtcttt tcttggtata actcttatgt ttatcagatt
    43441 cgtcagacta tatcagaagc ctttagacag gttttccctg aggttttagg ggcttatgag
    43501 aaaatccgct ttaaaggttt ggactatgaa tctgcccatg tttatggtca agaagcacct
    43561 gactttttca ctgttttaga aaatggtgtc ctgtatcaag tctttatgaa tgatggcttg
    43621 atgacaggaa ttttcctaga ccagcatgag gttcgcggta gtttagttga cggcttgact
    43681 atgggtaaat ccttgctcaa tatgttttcc tacacagcgg ctttttcagt agctgcggcc
    43741 atgggaggag ctagccagac aacttctgtt gatctagcca aacgttcacg agaattgtct
    43801 caagcgcatt ttcaggcaaa tgggctcagc acagacgagc atcgttttat agtcatggat
    43861 gtctttgagt atttcaaata tgccaaacgc aaagacttga cctacgatgt gattgtccta
    43921 gatccgccta gctttgctcg gaataaaaaa caaactttct ctgtggccaa ggattatcac
    43981 aagttgattt cccagagtct tgagatttta aatccgggag ggattatcat tgccagtacc
    44041 aatgctgcca atgtttcccg tcagaaattt acagaacaaa ttgataaagg ctttgcagga
    44101 agaagttacc agattttaaa caaatatggt cttccagcag attttgccta taataaaaaa
    44161 gatgaaagta gtaattacct caaggtgatt agtatgaagg ttagtaaatg aaattaatcg
    44221 tttcagtaat gccaagaagt ttagaggagg ctcaggctct ggatgccacg aggtacctgg
    44281 atgccgacat cattgaatgg cgtgccgact atctgcctaa agaagcgatt ttgcaggtag
    44341 ctccagccat ttttgaaaaa ttcgcaggcc gtgagttggt tttcacgcta cgaactcgct
    44401 ccgaaggtgg agaaatcgac ctttctccag aagagtatat ccatctaatc aaggaagttg
    44461 cgcaattcta tcaaccagac tatattgatt ttgagtacta tagctacaag gatgtttttg
    44521 aggaaatgct ggacttccca aatcttgttt tgagttacca taatttccaa gaaacacctg
    44581 agaacatgat ggaaatcttg tcagagttga cgatcctaaa tccaaaactt gttaaggttg
    44641 cggtgatggc tcacacggag caggatgtct tagacttgat gaactataca cgaggcttta
    44701 aaaccctcaa tcctgaacag gaatatgtga ccatttctat gggtaaggtg ggcaaggtct
    44761 ctcgtatcac tgcggatgtg actggttcga gttggtcttt tgccagtctg gatgaggtta
    44821 gtgcccctgg gcagatttct ctagctagca tgaaaaaaat cagggagatt ttggatgaag
    44881 cttgatggct atacacgttt agctgcagtt gttgccaatc ctattaagca ttctatttct
    44941 cccttcatcc acaatagagc ctttgaggcg acagctacca acggtgctta tgtggcttgg
    45001 gagattgaag cgagtgactt ggcagaaaca gtggccaata ttcgtcgcta ccagatgttt
    45061 ggcatcaatc tgtccatgcc ctataaggag caggtgattc cttatttgga taagctgagc
    45121 gatgaagcgc gcttgattgg tgcggttaat acggttgtca atgagaatgg caatttaatt
    45181 ggatataata cagatggcaa gggatttttt aagtgcttgc cttcttttac aatttcaggt
    45241 aaaaagatga ccctgctggg tgcaggtggt gcggctaaat caatcttggc acaggctatt
    45301 ttggatggcg tcagtcagat ttcggtcttt gttcgttccg tttctatgga aaaaacaaga
    45361 ccttacctag acaagttaca ggagcagaca ggttttaaag tggatttgtg tgctttagag
    45421 tatgtttctg aactgcaagc aaggattgcc gagtcggatt tgctagttaa tgccaccagt
    45481 gtgggcatgg atggccaatc ctctcctgtt cctgaaaaca tagtcttacc agaaactctc
    45541 ttagttgcag atatcatata ccaacccttt gaaacaccgt ttttgaaatg ggctagaagt
    45601 cagggcaatc cagcagtcaa tggtctggga atgttgctat atcaagctgc agaagctttt
    45661 caactgtgga caggcaagga aatgccgaca gaagagattt ggcagtcttt aacagaaaaa
    45721 taccaataaa gaaagggaga ctctcctatg aaaatcagaa tcgatattcc tcatcatcct
    45781 tatgatattc agattgaaaa aggttgtatg gcccaggctg gtcagtggtt gcgagaactc
    45841 tggcaaccgc aaaaggtagt cattgtgaca gataaccatg tagcctctct ctatgcagag
    45901 aaggtcaagc tcagcctaga agatgctggt tttcaggtag ctgtttttga tttcttagaa
    45961 ggtgaagaaa gaaagaattt aactactgtt cagaaagtct atgaatttct agtcaagcaa
    46021 ggtctgactc gtagcgatgg aatcgttgct cttggtggtg gcgttgttgg ggacctggct
    46081 ggatttgtag cctctaccta tatgcggggt attcactttg ttcagattcc gactagtttg
    46141 acagctcagg ttgattcttc tatcggtgga aagacaggcg ttaacacacc atttgctaaa
    46201 aatatggtgg ggacctttgc ccaaccagat ggggttctga ttgatccact tgttcttgaa
    46261 accctcggaa aaagagagtt gattgaaggg atgggtgaag ttatcaagta tggcttgatt
    46321 gaggatccag aactgtgggc tctcttgacg gggctgaatg gttctgttga gagcattttg
    46381 gaacatgcag agaccttgat tgaacattct tgtcaggtga agcgcaagat ggtggttgaa
    46441 gatgagttgg acaatggtat tcgtctttac ctcaattttg gccacactat tggccatgcc
    46501 atcgaagcga ctgccggtta tggcaaggtc atgcatggag aggctgttgc catgggaatg
    46561 gtacagattt ccaagattgc tgaggaaaaa ggcctcatgc cagctggcat tacccaatct
    46621 atcacagaga tgtgtcagaa attcggcttg cctgttgact atgaaaattg ggaagttgac
    46681 aagctttatc aggctcttac tcatgacaag aaagcgcgtg gtaacacctt gaaattggtc
    46741 ttggtgccag agcttggttc agcgaccatt catccagttt ctctggaaga gatgaaagac
    46801 tacttggtaa aataaggaga gtgtatgaga tatttaactg caggagaatc acacggcccc
    46861 cgtctaacag ctattattga gggaattcca gctggacttc cattgacagc tgaggatatc
    46921 aatgaggacc ttagacgccg tcagggtggc tacggtcgtg gtggtcgtat gaagattgag
    46981 agtgaccagg ttgtctttac ttcgggcgtt cgccacggga agacgacagg ggcgcctatt
    47041 actatggatg tcatcaataa ggaccaccag aaatggctgg acatcatgtc tgcggaggac
    47101 attgaagacc gccttaaaag caagcggaaa attactcatc ctcgcccagg tcatgccgat
    47161 ttggttgggg ggattaagta ccgttttgat gatttgcgaa attctttgga gcgttcatca
    47221 gctcgtgaaa ccaccatgcg ggtggcagtt ggtgcagtag ccaaacgtct cttggctgag
    47281 ctggatatgg agattgccaa ccatgtcgtg gtctttggtg gcaaggaaat cgatgttcct
    47341 gaaaatctga cagtcgctga aattaagcaa agagctgccc agtctgaagt ttctattgtc
    47401 aaccaagaac gagaacagga aatcaaggac tatattgacc aaatcaaacg tgatggtgat
    47461 accatcggtg gggttgtgga gacagtcgtc ggaggcgttc cagttggtct tggttcctat
    47521 gtccaatggg atagaaaatt ggatgcaaga ttggctcaag ctgttgtctc tatcaatgcc
    47581 tttaaagggg tggaatttgg tcttggcttt gaggctggtt atcgtaaagg cagccaagtt
    47641 atggatgaaa ttctctggtc taaagaagac ggttatactc gccgtaccaa taatctaggt
    47701 ggttttgaag gtggtatgac taatgggcaa cccatcgttg ttcgtggggt tatgaaaccc
    47761 attcctactc tttataaacc tcttatgagt gtggatatcg aaacccacga accttacaag
    47821 gcaaccgtgg agagaagtga tccgactgct cttccagctg caggaatggt catggaagca
    47881 gttgtagcaa cggttctggc gcaagaaatc ctcgaaaaat tctcatcaga taatcttgag
    47941 gaactaaaag aagcggtagc caaacaccga gactatacaa agaactatta aggagttcct
    48001 atggcaaaaa caatctatat cgcaggtctt gggttgattg gagcctctat ggcacttggt
    48061 atcaaacgcg atcatccaga ttatgaaatt ttaggttata atcgtagtca agcttcgaga
    48121 gacatcgcct tgaaagaagg catgattgac cgtgcaacgg atgattttgc tagttttgct
    48181 cctttggcag atgtcattat cctcagcttg ccaatcaaac aaactattgc tttcattaag
    48241 gagttggcca atttggattt gcgagaaggc gttattattt cagatgctgg ttcgaccaag
    48301 tcaaccattg tggatgcggc ggagcagtat ttggctggca agtctgttcg ctttgtcggg
    48361 gcccatccca tggctggtag tcacaagaca ggggctgctt cggcagatgt caatcttttt
    48421 gaaaatgcct attatatctt tacaccttca agcctgacaa gtcaggacac gcttaaggaa
    48481 atgaaggatc tgctttcagg tcttcatgct cgttttatcg agattgatgc caaggagcat
    48541 gatcgtgtca cttctcagat tagccatttt cctcatattt tggcttctag tctcatggag
    48601 cagactgcgg tctatgctca agagcatgag atggcaaggc gctttgcggc aggtggtttt
    48661 cgagatatga cccgaattgc ggaaagcgag ccaggaatgt ggacctccat tctcttgtcc
    48721 aatagcgaga ccattctgga tagaattgag gatttcaagg aacgtttgga agcgattggt
    48781 caggccatta gtaagggaga tgaagagcaa atttggaact tttttaacca agcgcgtgaa
    48841 caacgccaga caatggaaat ccataagcgt ggtggtgtgg atagctctta cgacctctat
    48901 gttgacgttc ctgatgaaga agatgtcatc ctgcggattt tggaactgct acgtgggact
    48961 tccttggtta acatccacat caacgaggaa aatcgtgagg atattcacgg aatcctacaa
    49021 atttcattta aaaatgctca agacttggaa agagccgagc atctcataac aaaaaatacc
    49081 gactatacag tcgtcattaa ataaggagaa gaacatgtca aatatttacg atagtgcaaa
    49141 cgaactcagt cgcggtctac gcggattacc agaatacaag gctgttaaag cagctaaaga
    49201 tgcgattgca gcagatgctg aggcaagcaa aatctttaca gaatatcttg cctttcaaga
    49261 ggaaattcaa aaactagcac agacaggtca aatgccagat gcgtccttcc aagctaagat
    49321 ggaaggcttt ggtaaacaga ttcaaggaaa tagcctcttg tcagaattct ttaccaagca
    49381 acaacaattg gccatttacc tttctgacat tgaaaaaatt gttttcgaac cagtttcaga
    49441 attgctgaaa taagaaaaga actatcctaa agtcaggaat ttttaaggaa tttctggctt
    49501 tttatgataa aataggtaaa agtattgcaa gtatgaggtc cagtatgaaa ctaaaaacaa
    49561 acattcgcca tttacatggt agtatccgcg tcccaggtga caagtctatc agccaccgtt
    49621 ccattatctt tggaagtttg gctgagggtg agaccaaggt ttatgatatt ctgcgaggtg
    49681 aagacgttct ttcgaccatg caggtttttc gtgaccttgg tgttgaaatt gaggataaag
    49741 atggggttat taccgttcaa ggtgtaggca tggctggctt aaaagcgccg caaaatgccc
    49801 ttaatatggg aaattctggc acctcgattc gcctgatttc aggtgtcctt gctggtgcag
    49861 atttcgaagt agagatgttt ggagatgata gtctttccaa acgtcctatg gaccgtgtga
    49921 cccttccact gaaaaaaatg ggcgtcagca tctcagggca aactgaacga gacttgcctc
    49981 cccttcgctt aaaagggacg aaaaacctaa gacctattca ttatgagttg ccaattgcct
    50041 ctgcccaagt caagtcagcc ttgatgtttg cagccttaca agctaagggg gagtcagtta
    50101 ttatcgaaaa agagtacacc cgtaatcata ctgaagatat gttgcaacaa tttggtggtc
    50161 atttaagtgt ggatggtaag aaaatcacag tccaagggcc acaaaaattg acgggacaga
    50221 aggtggtcgt accaggagat atttccagtg cagccttttg gttagtcgca ggtttgattg
    50281 ctccaaattc tcgtctagtg ctgcagaatg tggggataaa cgaaactcgc accggtatta
    50341 ttgatgtcat tcgtgccatg ggtggaaaat tggaaataac tgaaatcgat ccagtcgcta
    50401 aatctgcaac cttgattgtt gagtcttctg acttgaaagg aacagagatt tgtggcgctt
    50461 tgattccacg tttgattgat gaattgccta ttattgccct acttgcgacc caagcccaag
    50521 gtgtaacagt tatcaaggat gctgaggagc tcaaggtcaa ggaaacagac cgtattcagg
    50581 ttgtggcaga cgccttaaat agtatgggag cagatattac tcctacggca gatgggatga
    50641 ttatcaaagg aaaatcagct cttcacggtg ctagagtcaa tacgtttggt gaccaccgta
    50701 tcggcatgat gacagctatc gcagccctat tggttgcaga tggagaggtg gagcttgacc
    50761 gtgcagaagc catcaatacc agctatccta gtttctttga tgatttggag agcttgattc
    50821 atggctaagg tgttattagg gtttatgggg gctggaaaat cgactattgc aagaggcttg
    50881 gaccctaatt accttgatat ggatgctctg attgagaagc gcctaggtat gtccattgcg
    50941 aattttttcg ctgaaaaggg agaagcagcc tttcgtcagg tagaatcaga agtcctagct
    51001 gatttattac aaagagacca agtcgtgtca actggaggag gagtggttat ttctcagaga
    51061 aatcgtgact tactcaagac taatacagat aacatctacc tgaaagcaga ttttgaaacc
    51121 ctctacctac gtatcgcagc tgataaggac aatcagcgac cgctttttct aaataatagc
    51181 aaggaagaac tagtagctat ttttcaagaa agacaggctt ggtatgagga agtggctagt
    51241 cgggttttgg atgtgaccaa gctaagccca gaggaaatta tagaggaact aagatgaaaa
    51301 ttgcttatct aggtcccaaa ggatcatttt cacaccacgt tgtgcagaca gcttttcctc
    51361 atgaggaatt gcaggctttt gccaacatta cagatgtcat caaggcttat gagcaaggat
    51421 tagtggacta ttctgtggtg ccagttgaaa attctattga gggtagtgtt catgaaacct
    51481 tggactatct ttttcatcag gctcacatcc aagcagtagc agaaatcgtt cagcctattc
    51541 atcagcagtt gatggtggtt ccaggccata ctaagattga aaagattttt tcacatccac
    51601 aggccttggc tcaaggaaag aaattcatcg atgaacaata tccagaggct caaatcgagg
    51661 taacagctag tacagcttat gcggcccgtt ttatttccga acatccagat cagccctttg
    51721 cagcaattgc acctagaagt tctgctgaag aatatggatt ggaactgatt gccgaggata
    51781 ttcaggaaat ggaagccaat ttcacacgtt tctggcttct aggagctgaa aagcctagta
    51841 ttcccttgca agcacaaact gaaaagatga gtttggcctt gacattacct gacaaccttc
    51901 caggtgcact ttataaggcc ctgtcgacct ttgcttggcg aggaattgac ttgacaaaaa
    51961 ttgaaagtcg tccactcaag acagcactgg gtgaatactt tttcattatc gatgtggatt
    52021 ataccgataa ggacttggtc cactttgccc aaaaagaatt agaagcgatt ggaatccagt
    52081 ataaaattct gggtgcctat cctatttatc caatatcaga ccatggaaag gagagaagat
    52141 gagtaaagaa aatcccttaa gtcatcatga gcagttgcgt tatgattatt tgctaaaaaa
    52201 tattcactat ctcaatgaga gagaaaaaaa tgagtttgtc tatttgcaag aaaagctaac
    52261 tcttgctagg ggaaatagta gctctagctt ggaacaagaa agagaagagc aggttgactt
    52321 accaagctat gcgaaccgga gtcgctcaca atccaaatca caagcactct ctttccctcc
    52381 aaaaaagaaa agacggaagc tccgtcttaa acgaattttt atggtgattt tttcactttt
    52441 ggtctgtgtg gctttggcca tggtattcat gtttttgcgt ggttaccaag atgctagcgc
    52501 aaagaaaact gctgatgccc gggcagctca agtagaagtc tttaatggtc aggacactag
    52561 agatggagtt aatattttaa tcatgggtac tgatggtcga atcggccaga acagtgttga
    52621 gacacgaact gactctatta tggtattaaa tgtcgggggc tcagataaga aaatgaagct
    52681 agtcagtttc atgcgtgata atttggtcta tatagatggt tatagtcaag tgattaacgg
    52741 tagaaaacag acagataaca agttaaacgt agcctacgag ttaggagaac aagaagggca
    52801 aaaaggggca gaaatggttc gccaagtctt gaaagataat tttgacttgg acattaagta
    52861 ctacgccttg gttgatttcc aggcctttgc cacagcgatt gacacgcttt tccctgatgg
    52921 ggtgacgatt gatgctcaat tttcaacatt gaatgggcgt cccctaacag aagctacagt
    52981 cggagatgat ttatacgcta ccgagactga gtctccaacc caaaccatta aagtcggaaa
    53041 acagcagatg aatggctcga ccctgctcaa ttatgctcgt ttccgtgatg atgatgaggc
    53101 ggattacggc cgtacaaaaa gacagcaaca agttttaaca gcaattttag agcaaattaa
    53161 agatcccact aaacttttca ctggttctga agctcttgga aaggtttttg ctatgacctc
    53221 aaccaacgta ccctatactt tcctcctaac aaacggttta tctgttttgg atggagcaaa
    53281 aaatggtatt gaaaaattga cgattccaga actgggtgac tgggtagatg cctatgatgt
    53341 ttatggaggc ttgggcttgc tggttgatca aaacaaatat caaaccaagc tcgctcaaat
    53401 gggcttgaga taagataata ctcaatgaaa atcaaagtgc aaattaggaa gctagccgca
    53461 ggctgctaaa aacacagttt tgaggttgta gataagactg acgaagtcag ttacctatac
    53521 ctacggcaag gtgaagctga cgttgtttga agagattttc gaagagtata agacagaaaa
    53581 atcaaagttt gatagctatt tggatagcag tcaggctttg attttttaca gtctgcaata
    53641 gattttcacc ccttgtttgt ggtataatga aacgatacga tagaaagaat aatgaacaat
    53701 atgactgatt taaaagcaat tcaggctcgt agtctggaga tggctgaata ttttgtggtc
    53761 ttttgtaaag aacatgattt gctctgttat ctctgtggcg gaggcgctat tggtgccctt
    53821 cgaaacaagg gatttattcc ttgggacgac gacctagact tttttatgcc tcgtaaagat
    53881 tatgagaaat tagcagaatt atggcctcgt tatgcagatg aacgttattt cttgtcaaag
    53941 agtcacaaga attttgttga tcgtaatctt tttattacca ttcgtgacaa ggaaaccacc
    54001 tgtatcaagc cttatcagca ggatttggat ttgccacatg gtctggcctt ggatgttttg
    54061 cctttggatt attatccgaa aaatccagct gagcggaaaa aacaggttcg ttgggccttg
    54121 atttattcac tcttttgtgc gcaaactatt ccagaaaagc atggtgctct catgaaatgg
    54181 ggaagtcgca ttttactggg tttgactcca aaatctctcc gttatcgcat ctggaaaaaa
    54241 gctgagaaag aaatgactaa gtatgatttg gctgattgtg atggcattac agaattatgc
    54301 tcaggtcctg gctacatgag aaacaagtac ccaatcacat cttttgaaga caatcttttc
    54361 ttgccatttg aaggaacaga gatgcctatt ccaatcggct atgatgtcta tctcagaact
    54421 gcttttgggg attatatgac gcctccacca gcagacaagc aggtaccgca tcatgatgct
    54481 gtcatcgctg atatggataa gtcttataca gaatacaagg gagaatatgg tggctaagaa
    54541 aaaaatctta ttttttatgt ggtctttttc tcttggaggt ggtgcagaga agattctatc
    54601 aaccattgtt tcaaatctgg atccagaaaa gtatgatatt gatattcttg aaatggagca
    54661 ctttgacaag ggatatgaat ctgttccaaa gcatgtacgc attttaaaat cccttcaaga
    54721 ttatcgccaa accagatggt tacgagcttt tttgtggaga atgagaattt attttccaag
    54781 actgactcgt cgtttgcttg taaaagatga ttatgatgtt gaagtttctt ttaccattat
    54841 gaatccacca ctgttgttct ctaaaagaag agaagtcaag aagatatctt ggattcatgg
    54901 aagtattgaa gaacttctta aggatagctc taaaagagaa tcacatagaa gccagttgga
    54961 tgctgcgaat acaattgtag ggatttcaaa aaagaccagc aattctatca aggaagttta
    55021 tccagattat gcttctaaat tacagacaat ctacaatgga tatgattttc agactattct
    55081 agaaaaatct caagagaaga tcgatatcga gattgctcct caaagtatct gtactatcgg
    55141 acggattgag gaaaataagg gttctgaccg tgtagtggaa gtgatacgat tattacacca
    55201 agagggaaaa aactatcatc tctattttat cggggctggt gatatggaag aggaactgaa
    55261 aaaacgagtc aaagagtatg agattgagga ctatgtacat ttccttggtt atcaaaaaaa
    55321 tccttatcag tatttatctc agacgaaagt tctcttgtct atgtctaaac aagaaggctt
    55381 tcctggagtg tatgtggagg ccttgagtct gggactccct tttatctcta cggacgttgg
    55441 aggggctgag gaattatccc aagaaggacg atttggacaa atcattgaga gcaatcaaga
    55501 ggcagctcag gcgattacta attacatgac ttctgcctca aactttaatg tcgatgaggc
    55561 tagccaattc attcaacaat ttacaattac aaaacaaatc gaacaagtag aaaaactatt
    55621 agaggagtag catggaaact gcattaatta gtgtgattgt gccagtctat aatgtggcgc
    55681 agtacctaga aaaatcgata gcttccattc agaagcagac ctatcaaaat ctggaaatta
    55741 ttcttgttga tgatggtgca acagatgaaa gtggtcgctt gtgtgattca atcgctgaac
    55801 aagatgacag ggtgtcagtg cttcataaaa agaacgaagg attgtcgcaa gcacgaaatg
    55861 atgggatgaa gcaggctcac ggggattatc tgatttttat tgactcagat gattatatcc
    55921 atccagaaat gattcagagc ttatatgagc aattagttca agaagatgcg gatgtttcaa
    55981 gctgtggtgt catgaatgtc tatgctaatg atgaaagccc acagtcagcc aatcaggatg
    56041 actattttgt ctgtgattct caaacatttc taaaggaata cctcataggt gaaaaaatac
    56101 ctgggacgat ttgcaataag ctaatcaaga gacaaattgc aactgcccta tcctttccta
    56161 aggggttgat ttacgaagat gcctattacc attttgattt aatcaagttg gccaagaagt
    56221 atgtggttaa tactaaaccc tattattact atttccatag aggggatagt attacgacca
    56281 aaccctatgc aaagaaggat ttagcctata ttgatatcta ccaaaagttt tataatgaag
    56341 ttgtgaaaaa ctatcctgac ttgaaagagg tcgctttttt cagattggcc tatgctcact
    56401 tctttattct ggataagatg ttgctagatg atcagtataa acagtttgaa gcctattctc
    56461 agattcatcg ttttttaaaa ggctatgctt ttgctatttc taggaatcca attttccgta
    56521 aggggagaag aattagtgct ttggccctat tcataaatat ttccttatac cgattcttat
    56581 tactgaaaaa tattgaaaaa tctaaaaaat tacattagaa cgggggtgac caagtgattg
    56641 atgggaaacg attattattt agtttgacca tagtcagtta taccttgacg ctagtaagtg
    56701 gaattgtgta tctgtttaat aataataatg ttagcttact ttctacttta ttgttcttgt
    56761 tggttagtag cttaattgct tgttggaatg atatcaagta ttacttaatc cattttattt
    56821 tctatttaac catttttgta tttctggtat caagaccgac cattgattat tttagggatg
    56881 gtgctttgga tacctatcat ccaatagcct atcgttttgc ctttatagtt gtcatggttt
    56941 cgattctggg cttgaccaca ggaggcgtcc tggctcgtta cttcatagct aggaagaaaa
    57001 taaaagtagc aaatatagga aattctctaa aagaggttta tatcaagcgg ttacgctttg
    57061 tatcactagg agtttttctt ctaacttatc ctttctattt cattcggtta tttgaacggc
    57121 tcttgtatcg tttgcagact tcctactatg cctactatgc aaattttgaa agtaaactgc
    57181 cttattttac ctacattttg tctaccttta cggtctatgc aatgtgtatg tatctggcaa
    57241 ccaagccaaa gaaattgcag gccacagcag tgcttgtctc ctttattgca gctaatacta
    57301 ttcatttggc aattgggaca cgaaatccct ttattttaag tattttattt gcttttgttt
    57361 attactttat gcgggagcaa actgaaaaag gaaaatggat tgggtttaaa gaaaagttag
    57421 cgatttttgt aggttctcct attctcatgt tagcgatggg agtactcaat tatgtacggg
    57481 ataatgtcca agtttcccat acaggtttct gggatatctt acttgacttt atctataaac
    57541 aagggactag ttttggtgtt ctggctcgag gttttctatt taacagtagc ctcccttacc
    57601 gagatttccg taattttact tttggtcctg ttcttgatta ttttgcaagg gggagtttgg
    57661 gagccatttt cggaggaaaa gcctttgaac atacaaccaa tagtgtggaa ctagctattg
    57721 atagtaatag ttatgcccac aatctatcct atcttgtctt gaacaaggaa tacttgaaag
    57781 ggcatggtat cggaagtagt tatatcatgg agttgtatac cgactatggt atgattggag
    57841 tctttctgct tagtttctta ctcggcgtat tatttatagc catgctgcaa gtagcctatc
    57901 gctcaaggac aatcctattt gctttatccc tactcatctt gaataatcta ttctttatgc
    57961 caagaagcag cttttcagaa agtttcttca atttatttac aatgcaattc tggggaattg
    58021 ttcttgtgat tatatttgta gcaaaaatgc ttacaaagga aaactagtat ctactaaaca
    58081 aaggagaaaa aaatcatgtt tgaacattat tcagtagctg atttgtttgc aaatctttat
    58141 aaaaagcgaa aagcaaatat tttagctctc atcgctttat ttgctctcat tgctgtacca
    58201 tttacaatta aagcagttag gaataaaaat actgtcaaag atacaacaag ttattcaact
    58261 tatcttatct ataaaatcac tcctccaaaa gagtcggcca aaacgatttt gaatcatcaa
    58321 attggtggtt atagtgattt ttatgggaaa ttgattgatg gtaatttgaa tggagcttat
    58381 cttttcaatg atgtagaacc cagtgagttg aaaaaaattg ccagtgaatt agacacgaca
    58441 gaaacaacct tgaaaaattc aacgaatgac tattggtgga aaaaattgac cgtctactat
    58501 atgattgacg atgcaggggt tggtgtgaaa attttgacat caagtaaaga tgccaatgac
    58561 ttgttagaga aaaaaattga tgggttgatt gagaaattta aacatgctta tgcaaatgtg
    58621 aaaattgaaa aactggaaac catcaactct aaagaattga acgcaaatgg tgaaacagcg
    58681 cttggcttaa atgtgaaaaa tctgattctt cgtttagttg ttattggagt ggtttgtgtg
    58741 attttggttg tgatgggaaa tgtgttagtt tatctcttta atccaacaat caatagagta
    58801 ggtgattttt ctcagtatca aattgatttt gtaacagaga ttacaacaat tgctaaccta
    58861 gcagatgttt tgtcatacaa aaatactgga caggaattga ccatcgttag ctcaaataaa
    58921 gctatcctag ataaattgaa acagagtcaa gaagctttaa aaggaatgca ttttgtagat
    58981 ttacaggatg tatcatctct tttggaaaga gatacagtcc ttcttgttga agagtacgga
    59041 gtgactcgtt ataagaaatt tgagcaaagt cttcaaattc tcagaaactt aaatcgttct
    59101 atcctcggtg tagcaacctt taaattataa gtattctgat gtataaggtc ttcaaagtcg
    59161 gctaagagcc gattttgaag gctttttcta tctgtctgca gaaattttct tttgataaaa
    59221 tcgtaaaaat ctagtataat agatagaact gaaagtatga ggttactagc aatgaaaatg
    59281 aaacaaatta gtgatacaac tttaaaaatc acgatgtctt tagaggattt gatggatcgt
    59341 ggaatggaga ttgctgactt tctcgttcct caagaaaaaa cagaagagtt cttttatgct
    59401 atcttggatg agctagagat gcctgatagc tttctggata caggcatgtt gagcttccgt
    59461 gtgactccaa aacctgataa ggtagatgtc tttgtgacca agtcaaagat tgaccaaaat
    59521 ctagattttg aagacttatc ggatttgcca gatatggaag aattggctca aatgtctcca
    59581 gatgaattta tcaaaaccct ggaaaaaagc atcgcagaca aaaccaagga tgatatcgaa
    59641 gccattcaat ctcttgagca agttgaagcc aaggaagaag agcaagagca ggctgaacaa
    59701 gaagctgaga gtaagaaaga accttacatc tactacatcc tttcttttgc taagttggct
    59761 gacttggtag cttttgccaa gacagtgact tttgaaatgg aaacttctga actctacaaa
    59821 atgaacgagc gctattattt gaccatttta gtggatattg aaaatcatcc aagcccatat
    59881 ccagcttggc tgttggcccg tatgcgcgag tttgcagagg atagtgatat cagtcgctca
    59941 gtcttacaag agtatggtca agtcttgatg agtcacgatg cagtgctcaa tctgcaaaaa
    60001 atcggctaat cctttctgga aagctatttc agattttaag aagagcgaat cgtctgattc
    60061 gttttttctt tttatactga aatagtgatt tactataata ggaattttca caaaattctg
    60121 ttataatggc tatattagaa aatttcgagg agataaagat gacagttaaa attgctttac
    60181 taggatttgg taccgttgca agtggtgtgc ctttcctcct aaaggaaaat ggaggaaaaa
    60241 tcaatcaatc agcacattca gatatcaaag ttgctaaggt attggtcaag gatgaagatg
    60301 aaaaaaatcg cttgcttgca gcagggaatg actttaactt tgtaaccaat gtggatgata
    60361 ttttatcaga ccaggatatt actatcgtag tggaattgat ggggcgtatt gagcctgcta
    60421 aaacctttat cactcgtgcc ttggaagctg gaaaacacgt tgttactgct aacaaggacc
    60481 ttttagctgt ccatggcgca gaattgctag aaatcgctca agctaacaag gtagcacttt
    60541 actacgaagc agcagttgct ggtgggattc caattcttcg tactttagca aattccttgg
    60601 cttctgataa aattacgcgc gtgcttggag tagtcaacgg aacttccaac ttcatggtga
    60661 ccaagatggt ggaagaaggc tggtcttacg atgatgctct tgcggaagca caacgtctag
    60721 gatttgcaga aagcgatccg acgaatgacg tagatgggat tgatgcagcc tacaagatgg
    60781 ttattttgag ccaatttgcc tttggcatga agattgcctt tgatgatgta gcccacaagg
    60841 gaatccgcaa tatcacacca gaagacgtag ctgtagctca agagcttggt tacgtagtga
    60901 aattggttgg ttctattgag gaaacttctt caggtattgc tgcagaagtg actccaacct
    60961 tcctacctaa agcgcaccca cttgctagtg tgaatggcgt aatgaacgct gtctttgtag
    61021 aatctatcgg tattggtgag tctatgtact acggaccagg tgcgggtcaa aaaccaactg
    61081 caacaagtgt tgtagctgat attgtccgta tcgttcgtcg tttgaatgat ggtactattg
    61141 gcaaagactt caacgaatat agccgtgact tggtcttggc aaatcctgaa gatgtcaaag
    61201 caaactacta tttctcaatc ttggctctag actcaaaagg tcaggtcttg aagttggctg
    61261 aaatcttcaa tgctcaagat atttccttta agcaaatcct tcaagatggc aaagagggtg
    61321 acaaggcgcg tgtcgttatc atcacacaca agattaataa agcccagctt gaaaatgtct
    61381 cagctgaatt gaagaaggtt tcagaattcg acctcttgaa taccttcaag gtgctaggag
    61441 aataagatga agattattgt acctgcaacc agtgccaata tcgggccagg ttttgactcg
    61501 gtcggtgtag ctgtaaccaa gtatcttcaa attgaggtct gcgaagaacg agatgagtgg
    61561 ctgattgaac accagattgg caaatggatt ccacatgatg agcgtaatct cttgctcaaa
    61621 atcgctttgc aaattgtacc agacttgcaa ccaagacgct tgaaaatgac cagtgatgtc
    61681 cctttggcgc gcggtttggg ttcttccagc tcggttatcg ttgctgggat tgaactagcc
    61741 aaccaactgg gtcaactcaa cttatcagac catgaaaaat tgcagttagc gaccaagatt
    61801 gaagggcatc ctgacaatgt ggctccagcc atttatggta atctcgttat tgcaagttct
    61861 gttgaagggc aagtctctgc tatcgtagca gactttccag agtgtgattt tctagcttac
    61921 attccaaact atgaattacg tactcgcgac agccgtagtg tcttgcctaa aaaattgtct
    61981 tataaggaag ctgttgctgc aagttctatc gccaatgtag cggttgctgc cttgttggca
    62041 ggagacatgg tgaccgctgg gcaagcaatc gagggagacc tcttccatga gcgctatcgt
    62101 caggacttgg taagagaatt tgcgatgatt aagcaagtga ccaaagaaaa tggggcctat
    62161 gcaacctacc tttctggtgc tgggtcgaca gttatggttc tggcttctca tgacaagatg
    62221 ccaacaatta aggcagaatt ggaaaagcaa cctttcaaag gaaaactgca tgacttgaga
    62281 gttgataccc aaggtgtccg tgtagaagca aaataaagaa tagaagatag gatggggaaa
    62341 ctcttgacca gagggtttca tatccttttt gtgaaaagaa gtttatactc aatgaaaatc
    62401 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac agtgttttga ggttgtggat
    62461 agaactgacg acgtcagctc aagacactgt tttgaggttg cagatagaac tgacgacgtc
    62521 agctcaagac actgttttga ggttgcagat agaactgacg acgtcagtaa catatatacg
    62581 gtaaggtgac gctgacgtgg tttgaagaga ttttcgaaga gtattagtta aaaacgtgat
    62641 aaaggagaaa taaaaatgac agaaatttat ctagcaggtg gttgtttttg gggcctagag
    62701 gaatattttt cacgcatttc tggagtgcta gaaaccagtg ttggctacgc taatggtcaa
    62761 gtcgaaacga ccaattacca gttgctcaag gaaacagacc atgcagaaac ggtccaagtg
    62821 atttacgatg agaaggaagt gtcactcaga gagattttac tttattattt ccgagttatc
    62881 gatcctctat ctatcaatca acaagggaat gaccgtggtc gccaatatcg aactgggatt
    62941 tattatcagg atgaagcaga tttgccagct atctacacag tggtgcagga gcaggaacgc
    63001 atgctgggtc gaaagattgc agtagaagtg gagcaattac gccactacat tctggctgaa
    63061 gactaccacc aagactatct caggaagaat ccttcaggtt actgtcatat cgatgtgacc
    63121 gatgctgata agccattgat tgatgcagca aactatgaaa agcctagtca agaggtgttg
    63181 aaggccagtc tatctgaaga gtcttatcgt gtcacacaag aagctgctac agaggctcca
    63241 tttaccaatg cctatgacca aacctttgaa gaggggattt atgtagatat tacgacaggt
    63301 gagccactct tttttgccaa ggataagttt gcttcaggtt gtggttggcc aagttttagc
    63361 cgtccgattt ccaaagagtt gattcattat tacaaggatc tgagccatgg aatggagcga
    63421 attgaagttc gttctcgttc aggcagtgct cacttgggtc atgttttcac agatggaccg
    63481 cgggagttag gcggcctccg ttactgtatc aattctgctt ctttacgctt tgtggccaag
    63541 gatgagatgg aaaaagcagg atatggctat ctattgcctt acttaaacaa ataaaacaga
    63601 gagtggggct tcccactttc ttcatttcta gaatatgaat agaagggatt tatgaaacac
    63661 ctattatctt acttcaaacc ctacatcaag gaatcaattt tagccccctt gttcaagctg
    63721 ttagaagctg tttttgagct cttggttccc atggtgattg ctgggattgt tgaccaatct
    63781 ttacctcagg gagatcaagg tcatctctgg atgcagattg gcctgctcct tatctttgca
    63841 gtaattggcg ttttagtggc cttgatagct caattttact cagcaaaggc agcagtaggt
    63901 tttgctaagg aattgacaaa cgatctttat cgtcatattc tttccttgcc caaggacagc
    63961 agagaccgtc tgacaacttc tagtttggtt actcgcttga cttcggatac ctaccagatt
    64021 cagactggta tcaatcaatt cctgcgtctc tttttacgag cgcccattat cgtttttggt
    64081 gccattttta tggcttatcg aatctcagct gagttgactt tctggttctt agtcatggtt
    64141 gccattttga ccattgtcat tgtagggtta tctcgattgg tcaatcctct ctacagtagt
    64201 ctcagaaaga aaacggacca actggttcag gaaacgcgcc agcaattgca agggatgcgg
    64261 gttattcgtg cttttggtca agaaaaacga gagttacaga tttttcaaac ccttaaccaa
    64321 gtttatgcta gattacaaga aaagacaggt ttcttgtcta gtttattaat acctctgacc
    64381 tatctgattg tcaatggaac tcttctcgtt attatctggc aaggctatat ttcaattcaa
    64441 ggaggagtac tcagtcaagg tgctctcatt gctcttatca attacctctt acagattttg
    64501 gtggaattgg tcaagctagc catgctgatc aattccctca accagtccta tatctcagcc
    64561 aagagaatcg aggaggtctt tgcggaatct cccgaaaaca tccattcaga attagaacaa
    64621 aagcaagtta ccagtggtcg ggttttacaa gtccaagaat tgacttttac ctatcctgat
    64681 gcggcccagc cttctctgag agacatttcc tttgatatga ctcaaggaca aatccttggt
    64741 atcattgggg ggactggttc tggtaaatca agcttggtgc aactcttact tggactttat
    64801 ccagtagaca aggggaacat tgacctttat caaaatggac gtagtcctct taatttggag
    64861 cagtggcggt cttggattgc ctatgtacct caaaaggtca aactctttaa gggaactatt
    64921 cgttccaact tgactttagg tttaaatcaa gaagtatctg accagaaact ctggcaggcc
    64981 ttggagattg cgcaagctaa ggattttgtc agtgaaaagg aaggactttt ggatgcccta
    65041 gttgaggcag gggggcgaaa tttctcaggt ggacaaaaac aaaggttgtc tatcgcccga
    65101 gcagtcttgc gccaagctcc gtttatcatc ctagatgatg caacctcggc actggatacc
    65161 attacagagt ccaagctctt gaaagctatt agagaaaatt ttccaaacac gagcttaatt
    65221 ttgatctctc aacgaacctc gactttacaa atggcggacc agattctcct cttggaaaaa
    65281 ggtgagttgc tagctgttgg caagcacgat gacttgatga aatccagcca agtctatcgt
    65341 gaaatcaatg catcccaaca tggaaaggag gactagaatg aaacgacaaa ctgtaaacca
    65401 gacgctcaaa cgtttagccg tagatttagc aaaccatccc ttcctccttt tcctagcctt
    65461 tctaggaact attgcccaag ttggcttatc aatttaccta cctattctga ttgggcaggt
    65521 cattgaccaa gtcctagtgg ctggttcatc accagttttt tggcagattt ttctccagat
    65581 gctcttggtg gtaataggaa atactctggt acaatgggcc aatcctctcc tctataatcg
    65641 tctaatcttc tcttatacca gagatttacg ggagcgaatc atccataaac tccatcggtt
    65701 accgattgcc tttgtagata ggcaaggtag tggagagatg gttagtcgtg taaccacgga
    65761 catcgaacag ttggcagctg gcttgaccat gatttttaac caatttttca ttggtgtttt
    65821 gatgattttg gttagtattc tagccatgct ccaaattcat ctcctcatga ctctcttagt
    65881 cttgctgttg acgccactgt ccatggtgat ttcacgcttt attgccaaga gatcctatca
    65941 tctcttccag aagcaaacag agacgagggg aattcagact cagttgattg aagaatcgct
    66001 tagccagcag actataatcc agtccttcaa tgctcaaaca gaatttatcc aaagattgcg
    66061 tgaggctcat gacaactact caggctattc tcagtcagcc atcttttatt cttcaacggt
    66121 caatccttcg actcgctttg taaatgcact catttatgcc cttttagctg gagtaggagc
    66181 ttatcgtatc atgatgggtt caaccttgac cgtcggtcgt ttagtgactt ttttgaacta
    66241 tgttcagcaa tacaccaagc cctttaatga tatttcttca gtgctagctg agttgcaaag
    66301 tgctctggct tgcgtagagc gtatctatgg agtcttagat agccctgaag tggctgaaac
    66361 aggtaaggaa gtcttgacca gtgaccaagt taagggagct atttccttta aacatgtctc
    66421 ttttggctac catcctgaaa aaattttgat taaggacttg tctatcgata ttccagctgg
    66481 tagtaaggta gccatcgttg gtccgacagg tgctggaaaa tcaactctta tcaatctcct
    66541 tatgcgtttt tatcccatta gctcgggaga tatcttgctg gatgggcaat ccatttatga
    66601 ttatacacga gcatcattga gacagcagtt tggcatggtg cttcaagaaa cctggctcac
    66661 acaagggacc attcatgata atattgcctt tggcaatcct gaagccagtc gagagcaagt
    66721 aattgctgct gccaaagcag ctaatgcaga ctttttcatc caacagttgc cacagggata
    66781 cgataccaag ttggaaaatg ctggagaatc tctctctgtc ggccaagctc agctcttgac
    66841 catagcccga gtctttctgg ctattccaaa gattcttatc ttagacgagg caacttcttc
    66901 cattgataca cggacagaag tgctggtaca ggatgccttt gtaaaactca tgaagggccg
    66961 cacaagtttc atcattgctc accgtttgtc aaccattcag gatgcggatt taattcttgt
    67021 cttagtagat ggtgatattg ttgaatatgg taaccatcaa gaactcatgg atagaaaggg
    67081 taagtattac caaatgcaaa aagctgcggc ttttagttct gaataagcca ttctcttttg
    67141 aaagtttatg gacgaaaaaa gttgccttcg agtgactttt ttgttacaat agctagaaaa
    67201 attgttcact gtaatactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt
    67261 gctcaaaaca ctgttttgag gttgcagata gaactgacga agtcagctca aaacactgtt
    67321 ttgaggttac agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga
    67381 agtggtttga agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc
    67441 agcatgtaaa tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag
    67501 cagtcaagga ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag
    67561 ctgagcagat tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca
    67621 cccattctgc aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc
    67681 tcaatgacta tatttggcca gcagaatctg agtttactcc cgacatgact accaatgcgg
    67741 tcaaagaagc cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata
    67801 atcccaatgg tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt
    67861 gttatttttc tccgactctc ttttcttcag agacagaaac aactgctgag actataagta
    67921 gaactcgatc catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg
    67981 tagcacctca ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg
    68041 caaaagagct aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa
    68101 ttatcctcaa acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag
    68161 atcatccgtc cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg
    68221 catcttctca agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa
    68281 ttgctccaat tatccagctc caaaaagcgg gagtagcagt cggaattgcg actgactcgg
    68341 ttgcttccaa taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga
    68401 agatgaaaag tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa
    68461 tcgaaggggc taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc
    68521 aagcagattt tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata
    68581 tgctgtctca cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg
    68641 gagaacaggt tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaattacg
    68701 aaaaatttta aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta
    68761 tatacggttt aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc
    68821 gaggacaaaa cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg
    68881 cgtttttctt tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga
    68941 gtgaagcaat tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag
    69001 ctgctgcatc tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc
    69061 ttcgtcgtga gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc
    69121 gtcgtgcagc tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg
    69181 cagtagcatt ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta
    69241 aaaacgctga agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag
    69301 aagagattct tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt
    69361 ctgtacttca agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca
    69421 aagaagacgc ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta
    69481 taaaatttaa aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg
    69541 ctgaaattaa agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag
    69601 aatttggtgt aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg
    69661 gtgctgctaa agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg
    69721 ttatcaaagt tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg
    69781 acggtgcacc agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaag
    69841 ctaaattgga agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat
    69901 tgcggaatcc ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat
    69961 tgatttggtt tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg
    70021 gtagacacta gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag
    70081 gacagtcatc acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg
    70141 taaaagcaac tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat
    70201 ttggaaatgt tggaatttta gtcttggagg gacaataatg aagcgtatta ccgctaatca
    70261 atatcagaca tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta
    70321 taagaatatg aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt
    70381 gtctttgagc aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc
    70441 aaatttgatg gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag
    70501 tgacattttt agatgattac cataaaaaac ataactaccc actattttac gaatcctatc
    70561 ttcaaaacgt tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg
    70621 tagatgatca tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa
    70681 aagagggaat acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga
    70741 ttaacttcgc aaatttatta gattccttaa tttattagat tccttaatcg tctcagaata
    70801 tcaaatggaa ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata
    70861 gacaaagaaa tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc
    70921 attcagtttc tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt
    70981 gttttgagtt tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa
    71041 cggatttcgt tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg
    71101 tttcaaataa gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa
    71161 gagatacgaa acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa
    71221 gcaatatggc tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca
    71281 gctggattga gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga
    71341 atcgtttgta tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat
    71401 gggtagaaag gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac
    71461 tatgaaaaga ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct
    71521 atacttattg aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc
    71581 gtcactcatt tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat
    71641 gaaatctagg atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg
    71701 ttttagtctg attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca
    71761 tcaaattcct tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt
    71821 tctgtatcga gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac
    71881 aagtgtttta tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt
    71941 ttcacttggg atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg
    72001 actacatttg gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc
    72061 tgatttttag gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt
    72121 tgaaaagtta cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta
    72181 ctggtggaga gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga
    72241 ggagctagct atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga
    72301 aacagatgaa gttgatggaa tgcgatttag tacattcagt acaaa
//
LOCUS       DBEJZJ010000008        67617 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000008 DBEJZJ010000000
VERSION     DBEJZJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 67617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.08"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..248
                     /locus_tag="ACL3R8_000640"
     CDS             <1..248
                     /locus_tag="ACL3R8_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1313569.1"
                     /translation="KSSILKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFR
                     TLEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
     gene            245..463
                     /locus_tag="ACL3R8_000641"
     CDS             245..463
                     /locus_tag="ACL3R8_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313570.1"
                     /translation="MSISPRFEALEQAIAFKDLEKVREAFKKMNSTWTINESVVRYNS
                     IAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(520..762)
                     /locus_tag="ACL3R8_000642"
     CDS             complement(520..762)
                     /locus_tag="ACL3R8_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR1313571.1"
                     /translation="MKKDIHPEYRSVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(858..1793)
                     /locus_tag="ACL3R8_000643"
     CDS             complement(858..1793)
                     /locus_tag="ACL3R8_000643"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR1313572.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1897..2340
                     /locus_tag="ACL3R8_000644"
     CDS             1897..2340
                     /locus_tag="ACL3R8_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR1313573.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2456..2722
                     /locus_tag="ACL3R8_000645"
     CDS             2456..2722
                     /locus_tag="ACL3R8_000645"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR1313574.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            2719..3093
                     /gene="crcB"
                     /locus_tag="ACL3R8_000646"
     CDS             2719..3093
                     /gene="crcB"
                     /locus_tag="ACL3R8_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR1313575.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3087..3416
                     /gene="crcB"
                     /locus_tag="ACL3R8_000647"
     CDS             3087..3416
                     /gene="crcB"
                     /locus_tag="ACL3R8_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR1313576.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3535..3882
                     /gene="rplS"
                     /locus_tag="ACL3R8_000648"
     CDS             3535..3882
                     /gene="rplS"
                     /locus_tag="ACL3R8_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR1313577.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3924..3995
                     /locus_tag="ACL3R8_000649"
     tRNA            3924..3995
                     /locus_tag="ACL3R8_000649"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3957..3959,aa:Arg,seq:cct)
     gene            complement(4050..4856)
                     /gene="yidA"
                     /locus_tag="ACL3R8_000650"
     CDS             complement(4050..4856)
                     /gene="yidA"
                     /locus_tag="ACL3R8_000650"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR1313578.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(4869..6173)
                     /locus_tag="ACL3R8_000651"
     CDS             complement(4869..6173)
                     /locus_tag="ACL3R8_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR1313579.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6245..6622
                     /locus_tag="ACL3R8_000652"
     CDS             6245..6622
                     /locus_tag="ACL3R8_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR1313580.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            6713..7045
                     /locus_tag="ACL3R8_000653"
     CDS             6713..7045
                     /locus_tag="ACL3R8_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR1313581.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            7057..8628
                     /gene="ffh"
                     /locus_tag="ACL3R8_000654"
     CDS             7057..8628
                     /gene="ffh"
                     /locus_tag="ACL3R8_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR1313582.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKMDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(8823..10106)
                     /locus_tag="ACL3R8_000655"
     CDS             complement(8823..10106)
                     /locus_tag="ACL3R8_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR1313583.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKKRVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(10360..11073)
                     /gene="rsmG"
                     /locus_tag="ACL3R8_000656"
     CDS             complement(10360..11073)
                     /gene="rsmG"
                     /locus_tag="ACL3R8_000656"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR1313584.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            11167..11727
                     /locus_tag="ACL3R8_000657"
     CDS             11167..11727
                     /locus_tag="ACL3R8_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR1313585.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11729..12628
                     /gene="htpX"
                     /locus_tag="ACL3R8_000658"
     CDS             11729..12628
                     /gene="htpX"
                     /locus_tag="ACL3R8_000658"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR1313586.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(12777..14336)
                     /locus_tag="ACL3R8_000659"
     CDS             complement(12777..14336)
                     /locus_tag="ACL3R8_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313587.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(14575..14891)
                     /locus_tag="ACL3R8_000660"
                     /pseudo
     CDS             complement(14575..14891)
                     /locus_tag="ACL3R8_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            15061..15603
                     /locus_tag="ACL3R8_000661"
     CDS             15061..15603
                     /locus_tag="ACL3R8_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR1313588.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            15603..16232
                     /gene="nth"
                     /locus_tag="ACL3R8_000662"
     CDS             15603..16232
                     /gene="nth"
                     /locus_tag="ACL3R8_000662"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR1313589.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            16443..16964
                     /gene="pyrR"
                     /locus_tag="ACL3R8_000663"
     CDS             16443..16964
                     /gene="pyrR"
                     /locus_tag="ACL3R8_000663"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR1313590.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            16983..17906
                     /locus_tag="ACL3R8_000664"
     CDS             16983..17906
                     /locus_tag="ACL3R8_000664"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR1313591.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            17956..19035
                     /locus_tag="ACL3R8_000665"
     CDS             17956..19035
                     /locus_tag="ACL3R8_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR1313592.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            19348..22524
                     /gene="carB"
                     /locus_tag="ACL3R8_000666"
     CDS             19348..22524
                     /gene="carB"
                     /locus_tag="ACL3R8_000666"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR1313593.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLSSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(22800..23609)
                     /locus_tag="ACL3R8_000667"
     CDS             complement(22800..23609)
                     /locus_tag="ACL3R8_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1313594.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(23611..24414)
                     /locus_tag="ACL3R8_000668"
     CDS             complement(23611..24414)
                     /locus_tag="ACL3R8_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR1313595.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLTFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(24424..25911)
                     /gene="tacF"
                     /locus_tag="ACL3R8_000669"
     CDS             complement(24424..25911)
                     /gene="tacF"
                     /locus_tag="ACL3R8_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR1313596.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            26247..26954
                     /locus_tag="ACL3R8_000670"
     CDS             26247..26954
                     /locus_tag="ACL3R8_000670"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR1313597.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            26959..27981
                     /locus_tag="ACL3R8_000671"
     CDS             26959..27981
                     /locus_tag="ACL3R8_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR1313598.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            27998..28867
                     /gene="licA"
                     /locus_tag="ACL3R8_000672"
     CDS             27998..28867
                     /gene="licA"
                     /locus_tag="ACL3R8_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR1313599.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            28857..29735
                     /locus_tag="ACL3R8_000673"
     CDS             28857..29735
                     /locus_tag="ACL3R8_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1313600.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            29747..30436
                     /locus_tag="ACL3R8_000674"
     CDS             29747..30436
                     /locus_tag="ACL3R8_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR1313601.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            30522..31370
                     /gene="dprA"
                     /locus_tag="ACL3R8_000675"
     CDS             30522..31370
                     /gene="dprA"
                     /locus_tag="ACL3R8_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR1313602.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            32260..33303
                     /locus_tag="ACL3R8_000676"
     CDS             32260..33303
                     /locus_tag="ACL3R8_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR1313603.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            33470..35557
                     /gene="topA"
                     /locus_tag="ACL3R8_000677"
     CDS             33470..35557
                     /gene="topA"
                     /locus_tag="ACL3R8_000677"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR1313604.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            35778..36137
                     /locus_tag="ACL3R8_000678"
     CDS             35778..36137
                     /locus_tag="ACL3R8_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR1313605.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            36230..36862
                     /locus_tag="ACL3R8_000679"
     CDS             36230..36862
                     /locus_tag="ACL3R8_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR1313606.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            36906..37562
                     /locus_tag="ACL3R8_000680"
     CDS             36906..37562
                     /locus_tag="ACL3R8_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR1313607.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            37632..38675
                     /locus_tag="ACL3R8_000681"
                     /pseudo
     CDS             37632..38675
                     /locus_tag="ACL3R8_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            38687..39724
                     /gene="leuB"
                     /locus_tag="ACL3R8_000682"
                     /pseudo
     CDS             38687..39724
                     /gene="leuB"
                     /locus_tag="ACL3R8_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            39721..39990
                     /locus_tag="ACL3R8_000683"
     CDS             39721..39990
                     /locus_tag="ACL3R8_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR1313608.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            39994..40353
                     /gene="leuD"
                     /locus_tag="ACL3R8_000684"
     CDS             39994..40353
                     /gene="leuD"
                     /locus_tag="ACL3R8_000684"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR1313609.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            40515..41137
                     /locus_tag="ACL3R8_000685"
                     /pseudo
     CDS             40515..41137
                     /locus_tag="ACL3R8_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            41301..43232
                     /locus_tag="ACL3R8_000686"
     CDS             41301..43232
                     /locus_tag="ACL3R8_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR1313610.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            43219..44535
                     /locus_tag="ACL3R8_000687"
     CDS             43219..44535
                     /locus_tag="ACL3R8_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR1313611.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            44710..45696
                     /locus_tag="ACL3R8_000688"
     CDS             44710..45696
                     /locus_tag="ACL3R8_000688"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR1313612.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            45760..45831
                     /locus_tag="ACL3R8_000689"
     tRNA            45760..45831
                     /locus_tag="ACL3R8_000689"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45793..45795,aa:Arg,seq:ccg)
     gene            46014..46712
                     /gene="rnc"
                     /locus_tag="ACL3R8_000690"
     CDS             46014..46712
                     /gene="rnc"
                     /locus_tag="ACL3R8_000690"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR1313613.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            46703..50242
                     /gene="smc"
                     /locus_tag="ACL3R8_000691"
     CDS             46703..50242
                     /gene="smc"
                     /locus_tag="ACL3R8_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR1313614.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            50239..51033
                     /locus_tag="ACL3R8_000692"
     CDS             50239..51033
                     /locus_tag="ACL3R8_000692"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1313615.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            51033..51851
                     /locus_tag="ACL3R8_000693"
     CDS             51033..51851
                     /locus_tag="ACL3R8_000693"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1313616.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            51855..53132
                     /gene="ftsY"
                     /locus_tag="ACL3R8_000694"
     CDS             51855..53132
                     /gene="ftsY"
                     /locus_tag="ACL3R8_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR1313617.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(53178..54665)
                     /gene="zwf"
                     /locus_tag="ACL3R8_000695"
     CDS             complement(53178..54665)
                     /gene="zwf"
                     /locus_tag="ACL3R8_000695"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR1313618.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(54814..55554)
                     /locus_tag="ACL3R8_000696"
     CDS             complement(54814..55554)
                     /locus_tag="ACL3R8_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1313619.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(55554..57719)
                     /locus_tag="ACL3R8_000697"
     CDS             complement(55554..57719)
                     /locus_tag="ACL3R8_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR1313620.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            57889..58842
                     /locus_tag="ACL3R8_000698"
     CDS             57889..58842
                     /locus_tag="ACL3R8_000698"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR1313621.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAIVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            58919..60907
                     /gene="uvrB"
                     /locus_tag="ACL3R8_000699"
     CDS             58919..60907
                     /gene="uvrB"
                     /locus_tag="ACL3R8_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR1313622.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            60917..61480
                     /locus_tag="ACL3R8_000700"
     CDS             60917..61480
                     /locus_tag="ACL3R8_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR1313623.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            61446..61934
                     /locus_tag="ACL3R8_000701"
     CDS             61446..61934
                     /locus_tag="ACL3R8_000701"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313624.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            62007..62474
                     /locus_tag="ACL3R8_000702"
     CDS             62007..62474
                     /locus_tag="ACL3R8_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR1313625.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(62471..62986)
                     /locus_tag="ACL3R8_000703"
     CDS             complement(62471..62986)
                     /locus_tag="ACL3R8_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR1313626.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(62998..63525)
                     /locus_tag="ACL3R8_000704"
     CDS             complement(62998..63525)
                     /locus_tag="ACL3R8_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1313627.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(63807..64370)
                     /locus_tag="ACL3R8_000705"
     CDS             complement(63807..64370)
                     /locus_tag="ACL3R8_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1313628.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGITLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(64354..64905)
                     /gene="coaC"
                     /locus_tag="ACL3R8_000706"
     CDS             complement(64354..64905)
                     /gene="coaC"
                     /locus_tag="ACL3R8_000706"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR1313629.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(64917..65606)
                     /gene="coaB"
                     /locus_tag="ACL3R8_000707"
     CDS             complement(64917..65606)
                     /gene="coaB"
                     /locus_tag="ACL3R8_000707"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR1313630.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            65836..67506
                     /locus_tag="ACL3R8_000708"
     CDS             65836..67506
                     /locus_tag="ACL3R8_000708"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR1313631.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVDAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWGKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        20511 a        12194 c        14879 g        20033 t
ORIGIN      
        1 ataaatcaag tatcttaaag attccgacta atattggttt tgcatttatt cctccataca
       61 caccagagat gaaccccatt gaacaagtgt ggaaagagat tcgtaaacgt ggatttaaga
      121 ataaggcctt tcgaactttg gaagatgtca tgaatcaact tcaagatgtc atacaaggac
      181 tggagaagga ggtgataaag tccatcgtta atcggagatg gactagaatg ctttttgaaa
      241 gcagatgagt ataagtcctc gttttgaagc cttggaacag gctattgcct tcaaagattt
      301 ggaaaaagtc cgagaagctt ttaagaaaat gaattccact tggaccatca atgaaagtgt
      361 ggttcgttac aatagtatag ctcattatgg acgtgttgaa acagctattt ccttcctgcc
      421 tagtagcatg gaaaccgaac ctacagatga gtctggaaca tgaaaacagc agttgatttc
      481 aagaaacaaa aaagaacagc cgaaactgtt ctcttatcat tatttgagac cgtatttttt
      541 gttgaaacga tccacgcgtc catctgcttg agtgaacttt tgacgtccag tgtagaatgg
      601 gtgtgagtct gatgaaattt ccacacggat caatgggtaa gtttcgcctt cgaactcaac
      661 tgtttcgtta gagcgttttg ttgaaccgct aaggaattgg taaccagtag ttgtgtccat
      721 gaagacaact gagcgatatt ctggatggat atcttttttc attttgcaat atttcctttc
      781 tgccatggtc tctttgcgag ccatagattg ttaccatact agtctatcag attctgaaaa
      841 gtttggcaag tattttatca gtttttaagc aagtttttta acttttggta gatgatttcg
      901 ttttcttcta ggctatagga attagcacca cttgctagag ggtggcctcc accatcatgc
      961 tccttggcga tttcattgat aggatggatt ttactgcgta agcgaacgcg gtagtggcca
     1021 tcagcctgtt cgacaaaaat tccccagaga ctcactctgt caatgcgtcc aggtgcaccg
     1081 acaatggctg cagtttcagc atcggttaca ttgtattgtt tcaagacttc ttgactcagg
     1141 ataacgcgag cagcaccatt ttcatccact tccagatggt cgtagatgta gccttgcagt
     1201 ttagcaattt tgtagctcat agtgtccatt ttgcgagtga gagccgcaaa gtcaaagtta
     1261 tgttctctca aataagcagc caggcgaaga gtccgtgcag tggtagaagg gtagaggaag
     1321 cgacctgtat caccgacaat tcctgcaaag agcaactcag catcgcgatc tgccaaggct
     1381 agttgggttg tttgggcaaa tagggtgatc atctcgctag cgctacttga actagtatcg
     1441 acccaagaca ggtcaccgta tacatcatca tttggatggt ggtcaatctt aatgagaaaa
     1501 tcaccttgac tatagcgctt atcatcgata cgagcagtat tagctgtatc acagacgatg
     1561 acaagtgcgc cttggtaggc tctatcttca acaagatcca tctcagccat ccaagtaaga
     1621 gttggttcat caaaaccgac ggctttgatg gttttttctg ggaaatgatg ttccagcaag
     1681 gctttcaatc ccacctgact tcctaaggca tcagggtctg gtttcatatg acgatgaatg
     1741 ataatggtgt cgtattcttt aattttttct aaaatttgtt ggcaaatctc cataaataac
     1801 ctcaattctt tctcatttca ttgtagcaca agaattttta tttttaaaat gaaaaagatg
     1861 tgatataatg gagaaagata aattgaggag gacgatatgg cattagcaaa aattgtattt
     1921 gccagtatga ccggtaatac cgaagaaatt gcagatattg tagcagacaa attacgtgac
     1981 ttgggcttgg atgttgatgt tgatgaatgt acaactgttg acgcttcaga cttcttggaa
     2041 gcagacatcg ctatcgttgc gacctatact tatggtgatg gtgaattgcc agatgagatg
     2101 atggacttct acgaagacct agcagatctc aacttgaatg gcaaaatcta cggagtggtc
     2161 ggctcaggag ataccttcta cgatgaattc tgtaaggctg ttgatgactt tgaccgtgtc
     2221 tttgtgtcaa caggagcaga aaaaggttca gagtgtgtta aagttgatct ttctgccgag
     2281 gaagaagata ttgaacgctt ggaacaattc gcagaagaat tggttgctaa agtaggataa
     2341 gcataaaagt gcgctgatgt aatcaatcag tgcatttttc ttatcgagag ttgggatttt
     2401 actagcctaa ttgatggctt tttgatacaa taattcaaat aaaggaggag actgtgtgga
     2461 tttagatatt attcgtcaag aaatcgatca aatcgacgac caaattgtca aactgttaga
     2521 agaacgaatg cacttagttg aaggagttgt cgcttataag aaggcttcag ggaaaccgat
     2581 tttagatact aagagagaag cagttatttt tgaaaaggtt agaagtcgtg tagaggacaa
     2641 gcgctatcag gagactattg tcgcgacttt ttcggacata ctcaaacgtt cgcgtgatta
     2701 tcaggatcaa aatatcaaat gaaaaaagaa caattttatc cgctagggat ttttctagct
     2761 gctatgttgg gcggacttgt ccgctaccta gtttccactt ggttaccagc cagtccagat
     2821 ttcccttggg gcactctctt tgtcaactat ctgggaattt tctgcttgat ttatcttgtc
     2881 aagggctatc tggtctataa ggggactagt aagggcttga ttttagcact ggggacgggt
     2941 ttttgcggag gtttaacaac tttttccagc ctaatgcttg atactgtgaa gctgcttgat
     3001 acagggcgtt atcttagttt gatactgtat ttgcttttga gtatcggtgg aggcctgctt
     3061 ttagcttact atttggggag gaagaaatgg taatcgtcta tcttgcaatc gcctgtggct
     3121 tgggagcact cgtacggtat ttcttttctc gctataatca agcttctaaa ttgccactcg
     3181 gaacgctcat agctaatctt ttaggttgtt ttttaattgg agtattctac aatcatgtag
     3241 agtctaagga agtatatgct attctagcaa caggattttg tggcggttta acaacttttt
     3301 cgaccttgaa tgacgaactt caaagactgc taagtgataa gaaggtcttt tattcttacc
     3361 tgactttgac ttacataggt ggtttggttg cgattttttt aggaattttg ctataaattt
     3421 ctttactttt ttgtgaaaat ttggtaaact gtatcttgtg tgtaatggac gcacaagaat
     3481 acagtttatc cgctgaggaa gtttcctcaa gattgacaaa gataggagaa taaaatgaat
     3541 ccattaatcc aaagcttgac tgaaggtcaa cttcgtacag atatcccatc attccgtcct
     3601 ggtgacactg ttcgtgtaca cgcgaaagtt gtcgaaggta accgtgaacg tatccagatt
     3661 tttgaaggtg ttgttatcgc acgtaaaggt gctggaatct cagaaaacta cacagttcgt
     3721 aaaatctcta acggtgtagg tgttgagcgt atcttcccaa tccacactcc acgtgttgaa
     3781 aaaatcgaag ttgttcgtta cggtaaagta cgtcgtgcga aattgtacta cttgcgtgct
     3841 cttcaaggta aagcagctcg tatcaaagaa atccgtcgtt aattcgacta aaaaactctg
     3901 cttttcagca gagtttttat ctagctccct tagttcaatg gatataacaa ctccctccta
     3961 aggagtagtt gcaggttcga ttcctgcagg gggcagtaat tagacatcaa aaaccgctca
     4021 gctgagcggt ttttatctat tctttccttt tacagtaccc atgtacgaat agcatgggca
     4081 acgccggatt cgtcatttgt tttggtgatg tatttggcga tttttttgat ttctggattt
     4141 ccgttttcca tgactacagg gttgccaacg acttccagca tggcacggtc attttcttcg
     4201 tctccgatag ccatggtttc atctttggtt aatcctagtt tttcagctaa gtgagtaata
     4261 gctgaaccct tgtctacatt ctttttaagg agttcgaggt agaaaggagc agatttgttg
     4321 atagagtagt gctcgtaaaa ttcggctggt attttttcaa tcgcagcatc gaggatttct
     4381 ggttcatcga tgaacataca cttgacaatt tccttgccag ccatttcttc aggggtacgg
     4441 tagaagatag gcatgctgac gagggttgat tcgtgtacag tgtattttcc gatattgcga
     4501 tttgcagtat agataccgtc cttggtaatg gcatgcatgt ggacaccgag cttgcgactg
     4561 aggaattcca tatccagata atcctcatag gtcaaggatt cgctgataat ctcatggcca
     4621 gtagcagttt cttggacaag ggcaccattg aaggtcacca catagtcacc ttggtctctc
     4681 aactgcaagt cgtccagaag tttggcaaca cctgcgatgg ggcggccagt tgcaatcacg
     4741 actttgacac cagcttcttt ggcatcttgg atggcagaaa agacttcagg agtgatttcc
     4801 ttttggctgt tgactagggt tccgtcaata tcgacggcga ttagtttaat actcataaat
     4861 ttcctctttt agtttttatt tggggtaaaa tgatcgttct caatcaagtg taaaaattgc
     4921 tgggtgatgc ttgcgaagat gctgttttgg tctaacattt ctttcgggaa ataaaagcga
     4981 ttatctccgt ggcgacttcc agcaagggat tggacgatag gggacaggct agagagttct
     5041 gccagttctc catttttttg taaaatctca atctgtgtcc ttggattttc agattcggga
     5101 cggtaaatat cataagggag gtcaaagttc ttatgaatgg cagtatagta gtcgggatca
     5161 aagccgatgt cctcaaccaa ttttctcatg ctagcgagtt ggtcttggtc ttcttgtgaa
     5221 aaggtaatgg atttaaagac cttgcggttg acaaagcgat gcgataaatc tgcaagaatc
     5281 ttgtcaggac tggtcatcca gagttggaag taggtattca tcacaccatc atccagagcc
     5341 agatagtcag tcaaggtcac atttttttcg aagaaaggca ggaggtgtgg agaagttcgg
     5401 gcaaagaaat ccttgtcctc aggatagagt tccttggcgc gtttgagaag attctgtagg
     5461 agaacttcca tggcgcgtgt tgcggggtgg aaataaacct gcatgtacat ctggtagcga
     5521 ctgaggacgt agtcttcgat ggcgtgcatg ccattgcgct gaaaggcgat accattttcg
     5581 ataggacgaa tgactcggag gattcgagtc aggtcaaatt ccccatagga tgctcctgta
     5641 aaataggagt cgcgcaagag atagtccatg cgatctgcgt caatctgact agaaatgagc
     5701 tgcacgacct gcttgttagg ataggtatgg tctatgacac tggcaacttt ctctggaaaa
     5761 tcgggcgcta cttgtagcaa gacttggtga atctctgtct caggattttg aataatctcc
     5821 tgagtaatgg cttcatggtc tgtatcaaag agattttcaa aagtatggga gtaggcacca
     5881 tgcccaaggt cgtgtaggag agcagcggtc atggtcaaga gagactcggc aggattccat
     5941 tcctcaggat atttttcttc gaaaatctct gtgatgcgtc gtgcaatttc atagactcct
     6001 agacagtgag agaagcgact gtgttctcca ccgtggaagg tataactgga agttcccagt
     6061 tgtttgatcc ggcgcaaacg ctgaaattct tttgtattaa tcaagtcata gatgatttga
     6121 ttattgacat ggatgtagtt gtgaacaggg tcacggaata ctttttcgtt catatgacca
     6181 ttatagcaaa atcctgctct ttttggtaaa atagtaggac aagagacaag aaagagggcc
     6241 tgatgtgaag attcggatgc gaaatacaat tcagtttgat gagcagttgg aagtgattga
     6301 ccagctttat gatgtggaag tgcatgaaaa aggagattat agctacctgc ttttctataa
     6361 tgaggaaaag gaaaaagtag tgattaaatt tcatggtcaa gaacttatga tgagccgatt
     6421 ttctaatccc aagaccatta tgcgctttct aaaggatagc gatagtttag cctatattcc
     6481 tacacctatg ggcatgcagg agtttatcat ccaaacgagc cattatcaag ttgataggca
     6541 aaagattgaa ctagattatc aactacaaaa tcaagaggga catccttttg ccagctatca
     6601 attggaaatt acttggggct aggctcatgt ctttttcaaa tttagctatc tatcttcttg
     6661 gatcggcttc ctagtgtggt agattaggct aatttttggt ataataaaag ttatggaaat
     6721 cgaaaaaacc aatcgtatga atgcgctctt tgaattttat gcggcgcttt tgacagataa
     6781 gcaaatgaat tatatcgagc tctactacgc tgatgattac agccttgctg aaattgccga
     6841 ggagttcggt gtcagtcgtc aggctgtcta tgacaatatc aagcgaacag aaaagattct
     6901 ggaagattat gagatgaaat tgcacatgta ctcggattat attgtccgca gtcagatttt
     6961 tgatcagatt ttggagcgct atcccaagga taactttctg caggagcaga tagaaatttt
     7021 aacaagcatt gataatagag aataagagga agaaaaatgg catttgaaag tttaacagaa
     7081 cgtttgcaga acgtctttaa aaatctacgt aaaaaaggaa aaatctctga atctgatgtc
     7141 caagaggcaa ccaaagagat tcgcttggcc ttgcttgaag ccgacgttgc cttgcctgtt
     7201 gtgaaggatt ttatcaagaa ggttcgtgag cgtgcagtcg ggcatgaggt cattgataca
     7261 cttaatcctg cgcaacagat tattaaaatc gttgatgagg aactgacagc cgttttaggt
     7321 tctgatacgg cagaaattat caagtcacct aagattccaa ccatcatcat gatggttggt
     7381 ttacaagggg ctggtaaaac aacctttgct ggtaaattgg ccaacaaact caagaaagaa
     7441 gaaaatgctc gtcctttgat gattgcggcg gatatttatc gtccagctgc cattgaccag
     7501 cttaagacct tgggacaaca gattgatgtg cctgtctttg cacttggaac agaagtacca
     7561 gctgttgaga ttgtacgtca aggtttggag caagcccaaa ctaatcataa cgactatgtc
     7621 ttgattgata ctgcgggtcg tttgcagatt gatgagctcc tcatgaatga gcttcgtgat
     7681 gtgaaagcat tggctcaacc aaatgaaatc ttgcttgtcg ttgatgctat gattggtcag
     7741 gaagcagcca atgttgcgcg tgagtttaat gctcagttgg aagtgactgg ggtcatcctt
     7801 accaagattg atggcgatac tcgtggtggt gctgctctgt ctgttcgtca cattactgga
     7861 aaaccaatca agttcactgg tacaggtgaa aagattacgg acattgaaac cttccaccca
     7921 gaccgcatgt ctagccgtat ccttggtatg ggggatatgc tcactttgat tgagaaagct
     7981 tctcaggaat acgatgaaca aaaagccctt gaaatggctg agaagatgcg cgaaaacacc
     8041 tttgatttta atgatttcat cgatcaatta gatcaggtgc aaaatatggg gccgatggaa
     8101 gacttgctca agatgattcc aggtatggcc aacaatccag cccttcaaaa catgaagatg
     8161 gatgaacgcc agattgctcg taaacgtgcc attgtgtctt cgatgacacc tgaagagcgt
     8221 gaaaacccag atttgttaaa tccaagccgt cgccgtcgta ttgctgctgg ttctggaaat
     8281 acattcgtcg aagtcaataa attcatcaag gactttaacc aggctaaaca gctcatgcag
     8341 ggtgttatgt ctggggatat gaataaaatg atgaagcaaa tggggattaa tccaaataac
     8401 cttcctaaaa atatgccaaa tatgggagga atggatatgt ctgcccttga aggaatgatg
     8461 ggacaaggcg gtatgcctga cttatcagct ctcggaggag caggaatgcc agatatgagc
     8521 cagatgtttg gtggcggttt gaaaggtaaa attggtgaat ttgccatgaa acagtccatg
     8581 aaacgtatgg ctaacaaaat gaagaaagcg aagaagaaac gcaagtaaga caagagattg
     8641 atgcaaatct catttgatga gaaaataaag taaaaatttc tatgataaaa cgtacagtat
     8701 caaggtttta gaatatctga tattatacgt tttttgattt taataatttt gttaagacac
     8761 ttttattatg gtatgcgaaa aatccactca gctgtctgag tggattaggt gtatttagac
     8821 tcttagtctt tattttcgta tggcaagatc aagttcaaga tgattcctgt catggctgaa
     8881 agggcagtac ctgaaagtgt aactggacca agtttaagga tagctcctcc aagtccaaga
     8941 accaacatag cacttgcgat gatgaggttt cgcatttgag cgaaatcaac acgtttttta
     9001 atcaagactt tcaaaccatt gctggcgata accccataga gaaggattga cataccacca
     9061 agtacagcgt ttggaatagt tgaaatcaag gcagtgaatt taccaaggaa gctgagggca
     9121 atcgcgatga aggcagcgtt acggataact gagacagaag cgatacgagt cataccgata
     9181 acccctgtat tttctccgta agttgtattg gctggtccac caaggaaggc agaaacagaa
     9241 gttgcgatac cgtcaccaag aagagtacga tgaagacctg gttcttttaa gaattgacgg
     9301 ccacagattt gacccaaaac agtatggtct ccgatatgtt cagaaattgt tacgatagcg
     9361 attggcaaga tagcgatggc ttctggacca aagtaaagat tgtactcttt aaaggcacca
     9421 cctgtgctaa atggcaagta gaaaccagga atttcgaacc agttggcttt aagaactggt
     9481 gtaaagtcaa ccaagccaag agttagtgcg aaaaggtaac caccgataat ggcaaagagg
     9541 aatggaatga ttcgtaggaa gccttttcct tttgtattga taaaggcagc aattaggaaa
     9601 gtaacaacgg ctaccagagc atttttccaa tttccgtctg ctacaagacc tgcattggta
     9661 acagctgaac ctgcaagtcc aagaccgata acgatgatca taggaccgat aatgattggt
     9721 ggcaagagtt tatcaatcca ttttgttcct acaaatcgga tgctggtagc aacaaggaca
     9781 tagaccaaac cagtcaagat aacccctgtt tgggcagcag atacatcacc ccccatttct
     9841 ttcatagcca gtgacatagc tgtgataaag gcaaatgaag aacctagata aactggaact
     9901 ttaaaaccag tagcaatcat gtagatgagt gttccaacac ctgaagcaaa aagggcaaca
     9961 gatacaggca ttcccaaaat caatggtacc aagatggtcg caccaaacat ggcgaaaacg
    10021 tgttggaagc taaggagaat tccttttcca tccgaaggac gttggtcaac gtctagtaac
    10081 aaatcaacag ttgattcttg tttcatataa acctcacttt tgggcatcag aaaagagccc
    10141 attattttac agcaataggc cctcagagta agacttctct aaaatctaga ctttaaagag
    10201 tttcaaatat ttttgcgtct tcgtcacctc acgggatgac attaaaaacc tttgcttagg
    10261 atagtatagc agaaaaaaat gattttgtaa atcatttttt cccgagccta gaaataaaag
    10321 agcgaggctg attttgtaaa catttgttta ctaaaaaatt taaagtgggc gtttatttgg
    10381 cataccagcc ttacgtggat atttatttgg tgtttctttt ttcttttcta ccactgtgat
    10441 atagcgcgga tctctattcg gtagggcgta gctgagattg tcttcgacct tactaaaaag
    10501 gagattgagg gcattcttag cttctaataa ttcctcaggc gcattgctgg ccttgagtgc
    10561 caatagtttg ccaccaacct taaggtaggg aatagtcaat tcagatagga cctgcatacg
    10621 ggcaaccgca cgagctgtta caaaatcata ttgagcacgg aagttcttgt cttgggcaaa
    10681 atcttcggca cgtccgtggt agaaatgaac tccgttcaaa tccagttctt gagccaagag
    10741 ttgtaggaag ttgatgcgct tattgagtga atcaataatg gtcacatcta actccggata
    10801 gagaattttc attggtagac taggaaatcc tgccccagcc ccgatatcaa gaagtttgat
    10861 agtttcattg ggaatcaaac cttgaagaat gggtgcaatc gaatcgtaaa aatgtttgag
    10921 ataaacttct tccttgtccg taatcgccgt caaattaatc ttctcattcc actcgaccaa
    10981 gagctcaaaa taacgttcaa attgttcttt ttgctggtcc gaaagtggaa gattctgctc
    11041 ggcaagcaag ttgtaaaatg tttttggttt catagttatt tccttcttta gtatcatctt
    11101 attttaccac aatcatagaa aatttgatat actggtacta atctaaaagc agaaaggact
    11161 tatattatga cttggattat tcttggagtt ttagctcttg ttgttatttt tgtgattgtt
    11221 agctataacg gtttggttaa aaatcgtatg caaaccaagg aggcttggag tcagattgat
    11281 gttcagttga aacgtcgaaa tgacctcttg ccaaacttga ttgagactgt aaaaggttat
    11341 gccaaatatg aaggttctac ccttgaaaag gtggcagaac tacgtaacca agtggcggca
    11401 gcgacttcac cagcagaagc tatgaaagcc agtgatgccc tcactcgtca ggtttcaggt
    11461 atttttgcag ttgcagaaag ctatccagat ttgaaagcta gtgctaactt tgttaaattg
    11521 caagaggagt tgacaaacac agaaaataaa atttcttact ctcgtcaact ctataacagt
    11581 gttgtcagca actacaatgt aaaattagaa actttcccga gcaatattat cgctggaatg
    11641 tttggattta aagcggcaga tttccttcaa acacctgaag aggaaaagtc ggttcctaaa
    11701 gttgatttta gcggtttagg tgactaagat gttgtttgat caaattgcaa gcaataaacg
    11761 aaaaacctgg attttgttgc tggtattttt cctactctta gctcttgttg gttatgcggt
    11821 tggttatctc tttataagat ctggacttgg tggtttggtt atcgcactga ttatcggctt
    11881 tatctacgct ttgtctatga tttttcaatc gacagagatt gtcatgtcca tgaatggagc
    11941 gcgtgaggtg gatgagcaaa cggcaccaga cctctaccat gtagtggaag atatggctct
    12001 ggtcgctcag attcctatgc cccgtgtttt catcattgat gatccagcct taaatgcctt
    12061 tgcgacaggt tctaatcctc aaaatgcggc tgttgctgcg acttcaggtc tactagctat
    12121 catgaatcgt gaagaactag aagctgttat gggacatgaa gtcagtcata ttcgtaatta
    12181 tgatatccgt atttcgacta ttgcagttgc ccttgctagt gctatcacca tgctttctag
    12241 tatggcaggt cgtatgatgt ggtggggtgg agcaggtcgc agacgaagtg atgatgaccg
    12301 agatggaaat ggtcttgaaa tcattatgct agtggtttcc ctactagcta ttgtactggc
    12361 acctctcgct gcaaccttgg ttcagctcgc tatttctcgt cagagggaat ttctggcaga
    12421 tgcatctagt gtcgagctga ctcgcaatcc ccagggaatg attaatgccc tagataagtt
    12481 ggacaatagc aaacctatga gtcgccacgt cgatgatgct agcagtgccc tttatatcaa
    12541 tgatcccaag aaaggtgggg ggttccaaaa actcttttat acccacccac ctatctcaga
    12601 acggattgaa cgtttaaaac atatgtaaaa tgaaggctgg aaaaaagtct ttaaaatctg
    12661 aaaaacgcat aatatcaggt gtgaaaactt gatattatgc gttttactat gggaagattt
    12721 acttcttttt ctcctaaaat tgtgtttttg ccccacctat ctgctatgtt gcaaatttat
    12781 aaatcttcta aattaactag cttcaaaccg tgttctgtca tgcgatagat gatcgagcag
    12841 acttctttta agaaacgacg gtcatgcgaa acagtgatga gaccgccagg ataagtggca
    12901 aagagttttc tgatttgggg ttgagaagtg ggagaaaagt ttcgtgtggg ttcatccagc
    12961 aggagaaagt ttggtttgcg caggactaaa tccaaaagca ggagttttcc ctgttgtccg
    13021 ccagataagg agcgaatttg atgctgcatt tctggataac tgaaattgag actagctagg
    13081 tgagattgga ttttctgtag ttcctctttt tccccagttt tactgagata ggctattggg
    13141 gataaatcca attgcagttt tttgtggtaa tcttgtggca taaaaccaag tgaaatctct
    13201 cttttatcat tcagaagtct ctgtaacttg gctaacagag ttgatttccc aacaccattt
    13261 ggcccgataa taccgatttt ttcttggcca cggacagtta gttgtagttt ttgaaccaaa
    13321 actcggtcgt caatggacaa attttctttt tccagttgga ctaagacttt agaagctggt
    13381 aatggttgga tgtctgaaaa gaaaagttgg atttgttcct cttcaagtgg cttttgagtc
    13441 atggactgag ctgccttttc gtagcgtttt tcttgtgaga ggacagtttt catcttttta
    13501 gccaataggc gaccggcagt actatctttg gtagctcgaa gcgcagtttc tacactttgc
    13561 ttgactctcc gatgtttttc catggtttta tcgtaggctc tttggttgtt agcagcttgc
    13621 tgactttgtt tggcaaaatt agcctttctc tgctcactat agctatcata gtctaaatgc
    13681 tctactagcg tttccgcttc tttacggtgt ttgaccagtc gcaagtgaac aatagtgtct
    13741 gccgtttcag aaagaaagtc ttcatcatgg gaaatgaaaa taacggtttg cctggtcttt
    13801 tgaatctggc cttttagcca atcaactgtc tcaaggtcta ggtcatttga aggttcatct
    13861 aaaaatagaa tctcaaaggg tttggctaac tcatggataa gctgaatttt caaagcttcg
    13921 ccccctgata gattgccaat cttttggtca cttgcgaaac gattgctatc aaaatgcaat
    13981 tcctccgcca aacgatagag gatactgtag tctaaatcaa tagaatctaa aaagaagtag
    14041 tcgtgtaaag ttttcttttt cagctcctcg ggaagttttt gaggaatgta ggccagtgac
    14101 tgatagtcag attggatgtt tcccttgata gtgaaatcag acaaagcttc ccccattaaa
    14161 attttaagta aggttgattt gccatttcct tcttcaccaa taatagcaac cttttccccg
    14221 tcttggatgg tcatgcttag gtcagataca agatctcgta aatctttgtt ttgtgtgatg
    14281 gttagatgat tgatttttat catatgattt ccctttctag aatgttcata gtgcataaca
    14341 aaaagctcta ctttacctag tagagcccaa agtctatgtc aaaaaaactc tattaacatg
    14401 ccagaaaaag agcataaaag agcacacaaa aagagacaaa aacaagatct actaaataaa
    14461 ggttctttat ttgatagact tagttgttca tgtctccctt acctccgagt attagtatct
    14521 ttatattata cctttaagga aattttgtca acagaaaact ggaaattcta tgctctaaaa
    14581 tccaaaaaca ggtccataga gacttagtac gtgtttgaca tgctcgtaat ggaatttatc
    14641 atagtttcgc caagcagtgc gtgcttgatc gtttagtttt aggctaccca gtccaatcag
    14701 aagactggtg ggttggtaaa atttctcaag atcaattaag atactgttgt tcaacttttc
    14761 cgttttttga gctcttgcat agtagtgttt agcagctctt gtagtcgaat atcatctgcc
    14821 gtaccctgtt tacagttttg gtagctttta tttaacttgg ataggagttg aatgagtttc
    14881 ttgtcttcca tgtgagcatc ctccttgatc tgatgtactc tttccctata gtatagcact
    14941 aaaaaacaaa actgtcatag taaatatgtt aaaattttga attttaatta caaagtttgg
    15001 tgtgctgatt tgtagccttt tcatggtata atcaagagag taaatcttta tggaggaagt
    15061 atgaaattaa atattcaaga aattcgtaag cagtctgaag gtttgaactt tgaacaaacg
    15121 ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa ttttagatgt aaaagatatc
    15181 cttgcagttg ggaaagtaca atatgaagac cgtatgtatt tcttagatta tcaactatct
    15241 tataccattg ttcttgcttc gagtcgcagt atggagccag ttgagttagt tgaatcttat
    15301 ccagtcacgg aagttttcat ggaaggcgca actaaccatc taaatcaaga aattttagat
    15361 gatgacttgg tcttgcccat cgaaaatgag gcgcttgacc ttgctgagag tgtatcagac
    15421 aatatcttgc taaacattcc tatcaaggtc ttgacggctg aagaagaagc tggtcaagga
    15481 tttgtctcag gaaatgactg gcaaatcatg acagaggaag aataccaagc tcaacaagca
    15541 gtaaagaaag aagaaaacag tccttttgct ggcttacaag gactatttga cggagatgaa
    15601 taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga agaaatcatt gccctcttcc
    15661 cagatgccaa gcctagtctt gattttacca atcattttga actcctggtt gcggtcatgt
    15721 tatcagccca gacgacagat gcagcggtaa ataaggccac accaggtctc tttgttgcct
    15781 ttccaacacc ccaagctatg tctgtagcga cagagagtga gattgcttca catatttctc
    15841 gcttgggatt gtatcggaat aaagctaaat tccttaaaaa atgtgcccaa cagttactag
    15901 acgattttga tggtcaagtc cctcagacac gtgaagaatt ggagagtttg gcaggtgttg
    15961 gtcgcaagac agccaatgtt gtcatgagtg taggatttgg gattccagcc tttgcagtgg
    16021 atactcatgt ggagcgtatt tgcaaacacc acgatattgt caaaaaatca gcgacgccac
    16081 ttgaggtgga aaagcgggtc atggatatct tgccgcctga gcagtggtta gctgcccatc
    16141 aggccatgat ttattttgga agagccattt gccatccaaa aaatccagag tgtgaccagt
    16201 acccacaatt atatgatttt agcaatttgt aagatgctac attgaaactt tttgcttgat
    16261 tttaagcatg ctttgtgcta tagtaaatga taactaaata ttcctttaaa cctgtcccgt
    16321 gaggcaggca aggagcgcga taaagtagaa gggtgaagtc tatactgtgt gcagtagggc
    16381 tcgcttggct ataaatttca agtctccttg tttaaggaga cttttctttt tggaggtttg
    16441 tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa acgagcgatt acgcgtatta
    16501 cttatgagat tatcgaacgc aacaaagatt tgaataagat cgtcttggct ggtattaaaa
    16561 ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt gaagcagtta gaaaatcttt
    16621 cagttcctgt tgtggaattg gatactaaac ctttccgtga tgatgttaaa agtggagaag
    16681 atacttcttt ggtttctgtc gatgtgacag accgcgaagt tatcttggtg gatgatgtgc
    16741 tctatacagg tcgtaccatc cgtgctgcta ttgataatat tgtcggtcat ggtcgtcctg
    16801 cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag agaattgcca atccgtccag
    16861 attacgttgg aaaaaatatc ccaaccagtc gttctgaaga aatcatcgta gagatgacag
    16921 aacttgatga ccaagacaga gttctgatta ctgaagaagc ttagaaagtt aaaggagtag
    16981 ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc catggaagac ctcactgtcg
    17041 atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa aaatggagcc cagcttccct
    17101 atgaagacca tccgattgtt tccaatctct tctttgagga ttctacacgg acacataagt
    17161 cctttgaagt cgcagagatt aaacttggat tggaacgact tgactttgat gtgaagacta
    17221 gttcggttaa taagggtgag acactttatg acaccatttt gactctgtct gctttaggag
    17281 tggatgtctg tgtgattcgc catccagagg tcgactacta tagagaattg attgctagtc
    17341 caacgattac gacttccatc atcaatggtg gagatggttc gggccaacac cctagccaga
    17401 gcttgcttga tttgatgacc atttatgagg aatttggcca ctttgagggt cttaaagttg
    17461 ctattgcagg tgacttggac cactcacgcg ttgccaaatc caatatgcag attttgaaac
    17521 gcttgggatc tgaactcttt ttcgctggac ctgaggaatg gagaagtcaa gagtttgcag
    17581 actatggaca gtttgtaacc attgatgaaa tcattgatca ggttgatgtc atgatgtttc
    17641 tccgtgtgca acacgaacgc catgatagtg gagctgtatt ttcaaaagaa gactaccatg
    17701 cccaacatgg cttgactcaa gaacgttacg atcgtttgaa agaaacagca atcctcatgc
    17761 acccagctcc aatcaatcgt gatgtagaaa tagcagacca cttggttgaa gcaccaaaat
    17821 cacggattgt ccaacaaatg accaatggtg tctttgttcg aatggcaatc ttagaatccg
    17881 tactagcgag tagaaacgcc aactaaaaca caagacgtta aaagacgcca gtgagcgtcc
    17941 acgagaggtg aaaatatgac aaaaagaatt ctagtattag aagatggcac agtttttgaa
    18001 ggcaaggcct tcggagcaga tattgatgta acaggcgaaa tcgtctttaa tacagggatg
    18061 accggctacc aagaatccat tacagaccag tcttataatg gacaaatctt gacctttact
    18121 tatcctttgg taggaaatta tggtattaat cgtgatgatt atgaatccat tattccaact
    18181 tgtaagggag tcgttgtttt tgaagaagcg cgtagagcta gcaactggcg caaccaaatg
    18241 accttggatg aatttttgaa agccaagaaa attccaggga tttcaggaat tgatacgcgt
    18301 gctcttacca agattatccg taagcatggt actatgcgtg caaccttgac ccatgttggg
    18361 gacagtatgg accatgtgac ggaccagctc caagcaacag ttttaccgac agacaatatc
    18421 aaacaggttt ctactaaaac gtcttatcca gctccaggag ttggtttgag cgtggtgcta
    18481 gtggactttg gtctcaagca ctcaatccta cgtgaacttt ctaaacgcaa ctgtaacgtg
    18541 acagttgttc cttattcgac aacggctgaa gaaattctcc atctcaatcc tgacggagtt
    18601 atgttgtcaa atggtccagg taacccagaa gacgttccac aagcactcga catgattcgc
    18661 ggtgtacaag gaaaaattcc aatctttggt atttgtatgg gacaccaact ctttgcaatg
    18721 gcaaacgggg ctaagaccta taagatgaag tttggccacc gtggattcaa ccatgcggta
    18781 cgtgaaatcg caacaggacg agtagacttc accagccaga accatggtta tgcagtcagc
    18841 cgcgaggatt tgccagagca cttgattatt acccacgaag aaatcaatga caagtcagtg
    18901 gaaggtgtgc gccacagata ccaacctgct ttctctgttc aataccaccc agatgcagct
    18961 cctgggccac acgacgctag ctacctattt gacgagttta tcgagatgat ggaagttttt
    19021 aaacaatcaa actaagaacg agtaaaagct cgtcggagaa tttatgtaac tgaacacgga
    19081 cggaaagctc agaatgtaga gaaaccaact tggattgtca atccttcctt gatttcctaa
    19141 aattcaatcg ctttctattc gtcctttgta tcttatttaa tgtcgccctg agaggcgacg
    19201 aatagaaagg agaagggtgc tccgtatttg ctgaactgaa tacgggctac ggacggtgct
    19261 aaaaagatag ttattcctag aactgacagt tcttcgtcat aactcctatt ttagctttgt
    19321 ccgcttgaca cccttaatat cttatatatg cctaaacgta ctgatattca aaaaattatg
    19381 gtgattggtt ctggtccgat tattattggt caggctgctg agtttgacta cgctgggact
    19441 caggcttgct tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa ctcaaatcct
    19501 gcaaccatca tgacggacaa ggaaattgct gacaaggttt acattgaacc gattacactt
    19561 gagtttgtga cacgtattct tcgtaaggaa ggtccagatg ccttgctacc aacactcggt
    19621 ggtcagacag gtctcaacat ggccatggaa ttatctaaaa atggtatcct agacgagctt
    19681 ggcgttgaac ttctgggtac caaattatct gccattgacc aagcggagga ccgtgacctc
    19741 tttaaacaat tgatggaaga gcttgaacaa cccattccag aatctgaaat tgttaacaca
    19801 gtagaagaag cagttgcctt tgcagcgaca attggctacc cagtcatcgt tcgtccagcc
    19861 tttacccttg gtggtactgg tggtggtatg tgtgccaacg agaaagaatt gcgtgaaatc
    19921 actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg ttcgattgcc
    19981 ggtttcaagg aaattgaata cgaagtgatg cgtgactcag ctgacaatgc cttggttgtt
    20041 tgtaacatgg aaaactttga cccagttggg attcacacag gggattccat tgtatttgcc
    20101 cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag cttgagcatt
    20161 attcgtgccc tcaagattga aggtggatgt aatgttcagc tagctcttga tcctaacagc
    20221 ttcaagtatt atgttatcga agtaaaccct cgtgtatcac gttcgtcagc ccttgcttct
    20281 aaagcgacag gatatccgat tgctaagttg gctgccaaga ttgcagtagg tttgaccttg
    20341 gatgaggtta taaacccagt tacaggttca acctatgcca tgtttgaacc agcccttgac
    20401 tacgtagttg ctaagattcc acgtttccca tttgacaagt ttgaaaaggg tgaacgccgt
    20461 ctcggtacac aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa catcgaggaa
    20521 tctcttctca aggcctgccg ctcccttgaa attggggtgc accacaatga aatacctgaa
    20581 cttgcagcag tttctgatga tgccttgatt gaaaaggttg tcaaagccca agatgaccgt
    20641 ctcttctacg tatcagaagc cattcgtcgt ggctacacac ctgaagaaat tgcagagctt
    20701 acaaaaattg atatcttcta tcttgataaa ctcttgcata tctttgaaat tgagcaagaa
    20761 ttgggtgctc atccacaaga tttagaagtt ttgaaaacag ccaaacttaa tggtttttca
    20821 gaccgtaaga ttgctgaact ctggggaacg actgatgata aagttcgcca acttcgcttg
    20881 gaaaacaaga ttgttccagt ttataagatg gtagacactt gtgcggcaga gttcgactcc
    20941 gaaacgccat atttctattc aacctatggt tgggaaaatg aatctatcag atctgataaa
    21001 gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt tgagtttgac
    21061 tacgcaaccg ttcactctgt taaggctatc caggcagctg gttatgaagc tatcatcatg
    21121 aactcaaacc cagagaccgt ttcaacagac ttctctgtat cagataagct ttactttgag
    21181 ccattgacat tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa gggagttatc
    21241 gttcagttcg gtggtcaaac agccatcaac cttgcggagc cattggcaaa agcaggtgtg
    21301 accatccttg gtacacaggt tgctgaccta gatcgtgccg aagaccgtga cctcttcgag
    21361 caagctctca aagaattgga tattccacag ccaccaggac aaacggctac caatgaagaa
    21421 gaagcagctc ttgcagctcg taagattggc ttcccagttc ttgtccgccc atcttatgta
    21481 cttggtggac gtgccatgga aatcgttgaa aacgaagaag accttagttc ttacatgcga
    21541 actgctgtta aggctagtcc agaccaccca gttcttgtcg actcttatat cgttgggcaa
    21601 gagtgcgaag ttgatgccat ttcagatggt aaaaatgtac tcattcctgg tatcatggag
    21661 catatcgaac gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc accacaaacc
    21721 ttgtcgcaaa aggttcagga gaccatcgca gactacacca aacgcttagc aatcggtctt
    21781 cactgccttg gaatgatgaa catccagttt gttatcaagg atgaaaaagt ctacgttatt
    21841 gaggtcaatc cacgtgccag ccgtactgtt ccattcctat ctaaggtaac caatattcct
    21901 atggctcaag tagcgaccaa actcattctt ggtcaaagtt tatcagaact tggctaccaa
    21961 aatggacttt accctgaaag cacccgtgtt catatcaagg cacctgtctt ctcctttacc
    22021 aaactagcta aggtagacag cttgctcggt cctgaaatga agtcaacagg tgaagttatg
    22081 ggttctgatg ctactttgga aaaagctctc tataaagcct ttgaagcttc ttatctacac
    22141 ttgccaactt ttggtaatgt cgtctttacc atcgctgatg atgccaaaga agaagccttg
    22201 aacttggctc gtcgtttcca aaacattggt tatggaatcc ttgcgacaga agggacagca
    22261 gccttctttg ctagtcatgg cttgcaagcc caacctgttg gtaagattgg tgatgacgat
    22321 aaggatatcc caagttttgt acgcaaagga agaattcaag ctatcattaa cacagtagga
    22381 acaaaacgaa ctgctgacga agatggtgag caaattcgtc gttcagccat tgaacacggg
    22441 gtgcccctct tcacagcgct agatacagct aatgccatgc ttaaggtact tgaaagtcgt
    22501 agctttgtta cagaagcgat ttaaatagaa aaaataagat atagcagcct gaatttagaa
    22561 cagtacacag ggatactaaa atatttctag aaattaattt gaattttcta attgatttgt
    22621 tcgcatctta tttcaatcta ctatagaaaa aagtctttaa aattataaaa cgcatcatat
    22681 caaggttttt caaaaaactt gatatgatgc gttttattgt gggaatatgt atttcatttt
    22741 ctactaaaat tatgtttttg aataacctct atcttagtag tctgtataat ccccctcaat
    22801 cagtttttgc gataagcttt aatgctatga ctataccact cttgcatttc ttttgatggt
    22861 ggtgtcatat aatcgccata catctgggtt aaaaattggt catatttttt gggaacaggc
    22921 aacatacggc cctcaaactc agttaaaatc agttctttaa aggtatcaac tgggaagatt
    22981 tctttcatcc cttccttacc gatcccaact cctccttcat attgaggagt gttggttaca
    23041 gcatttttga ctagttgatc aattttcttg taaaagtagc gaggattgac aaatcggaga
    23101 gcgtaccagc tacataatct aagaaaatct tttagtttgc tatcaccgtg aactgctcgt
    23161 gattttttga tataagctag ttgacgaaga gccacatact tatagctctt gtcgacaatg
    23221 ctcaagtctg taaatcgatc aattgggaag acatcgatga aaaggctggt atcatgacgc
    23281 ttgtacttaa catggtcttc tataacagta gaagtgtcca aaatcgatgc gaaattatgg
    23341 aagtaccaag aagatgtatc gtaggaaaga accttgtagc gagggtgatt ttcttcttca
    23401 ataatcttca gtaaacgctc ataatcctca cgataaaggg aaatatcaat atcatcatcc
    23461 caaggaatca tacctttgtg gcggatggct ccaagcatgg ttccataact gagaaaataa
    23521 ggaatatcat gtttcttaca agtctcatca atatagtcca gcagggctag ttgaatttct
    23581 ttaatttctt ttttttctaa atattgcatc ctaatcctcc aatttataag cgtgaaattc
    23641 atgactgtag aagcgttttt cttctggtgg tagggtcata taatctccat aaaattgtgt
    23701 caaaatagta tcaaattttt caggtgcagg aaggcttaaa ttctcaaagg ttaaatcgat
    23761 tgttttatca aaggtaccac ttgggaagac ttccttttcc ttaaattttg aaggaataaa
    23821 agccatatac tgcccatttt cacgactata tttttgaatt tctttctcga ttttatttgc
    23881 aaaataacga ggagaaaccg gtcgaaggag caaccaaaag gctgttcgta tccaatcttt
    23941 taaaaggcta tccttataga caatattttt atgtttactg aaagacagca gtttgaagct
    24001 ttccagttta taacaagtat caatgacctt aggatcatca aagcgatcta tagggaaaat
    24061 atcgataaag ataccagact cataggtttt tgtatttcga gtatcaataa ttttagtcgt
    24121 actgtcggtt atcttgataa agttgttaaa gtagttctta tcagtttcta aggataggag
    24181 cttatacttg cttttttcct tttgaaaaat gttaataaat cgttggtagt cttctctagg
    24241 catggacaga tcaatatcgt cgtcccaagg gataaagccc tcatgtcgaa ccgccccaat
    24301 cagagtaccg tagttaataa tatagttgat attgtgcttt ttacagagag tatcaatata
    24361 atccaaaatt tctaattcaa tttgtttggc atcttcaatg gttagttgtt tcattttaaa
    24421 ctcctatgat tttttgaatt tattttttaa ggctaggaca tggtttaaaa attcatagaa
    24481 aatgctatct tttgtgaaga caagtagact aatataagag atagctgata acaagacaat
    24541 caaaccagta ttaatcaaaa atggcaaatt aatgaccata tccacaggat acacgaaatt
    24601 aatcaggaaa taaattgcta caaaggaaag tgaaaagaga gagtatcgaa cagtatagct
    24661 aaagatatgt cccaagtgga tgagttgttt tctatggatg aaaatgatat agaaaacaag
    24721 tagagaagtc tctgataaca tagttgtcag taagtagtat tcgggagcca cgatatggtt
    24781 gaaaaagagg agactattca agcccaaatt gagtagccca gcaaagactg tatagactgt
    24841 gatacgtttt tcatagccat tggtaaagag aatttgggaa ccaagaatgg tatctaaggc
    24901 caggataatc gtacgaaaag cgaagagaga ggtcaagatg ccgcctccga tatatttttc
    24961 actaccgtaa agtaggatgg catttggtcc taaaaccatg agtccaaaac tcagtggaat
    25021 gataaagaag ttaaagattc gactacctct attaaccaga gaaacatagg cttctttgtc
    25081 tcctttcccc agatagtaac tgagacgagg cacactcact ccaattgcac ctgttacaac
    25141 cccagctata acggtcacaa ttcgctgagc tatggtatag taactaacgt tgacatcaat
    25201 ccctgtttta acgaggaaga ggcgatctaa aaaagtgaag agcatattgg cattggcaaa
    25261 gactaacatg gctgtcagag ggagaaagag tggtttaaaa tcacttaggt gaatcttaac
    25321 aagtttgatg tctcttttaa tccaaaaata actaatcagg tagttaatca gcgtcgataa
    25381 actcatcaca agtgtataga caacaatatc gtgttcattt ttaacaaata agaaaataga
    25441 gaccagcatc aggatacgga tgaaggcagt tttgtaaaag agaaaactgt aattttccag
    25501 agcttcattg acccattcga ttgaaaaaat ctgggcaatg agttgaatcc ccataacaag
    25561 gtagaccttt ttgacgattg gattatcagt aaagaagaga ggataggcta ggatatagac
    25621 agcagtggtc aaaatcgtac aagcgatgca caaataaaaa agactagaaa aggttctgtt
    25681 aagatctttt ttgttatcct tgacattact gatagccctt aaaccgtagt tatagacacc
    25741 ataagttgca aagggcaaga aaaatgacaa aatagtgtcg actgagttga agtaaccata
    25801 gtcagttcgg tccaagacac gcgcgacata ggttccagtt aggatgggaa aaataatatt
    25861 caagacacga attcccatgt aagatagagc atttaatttt atacttttca ttcaatttac
    25921 ctcgtttttc attatatcat aaagttagct aataagaaat gaagggcagt aagtcaagta
    25981 atcactttga agtttcaaat cttaagtttt aagttttctt taaggaaagt atattattct
    26041 gaaggactct aaaatttcgc agccatttat tagtaattgc tacagaattc ctagtcatta
    26101 ctagaaatgg actagtttct ttgaataata gaactgcata attctcctat tctagaaggg
    26161 gaggaccagt atttctttta tgataggact agattgtggt ataatagaga gaataagttt
    26221 ttttagtaag acaaaggaga aaatagatga tttatgcagg aattcttgcc ggtggaactg
    26281 gcacacgcat ggggatcagt aacttgccaa aacaattttt agagctaggt gatcgaccta
    26341 ttttgattca tacaattgaa aaatttgtct tggagccaag tattgaaaaa attgtagttg
    26401 gtgttcatgg agactgggtt tctcatgcag aagatcttgt agataaatat cttcctcttt
    26461 ataaggaacg tatcatcatt acaaagggtg gtgctgaccg caatacaagt attaagaaaa
    26521 tcattgaagc cattgatgct tatcgtccgc ttactccaga ggatatcgtt gttacccacg
    26581 attctgttcg tccatttatt acacttcgca tgattcagga caatatccaa cttgcccaaa
    26641 atcatgacgc agtggacaca gtggtagaag cggttgatac tatcgttgaa agtaccaatg
    26701 gtcaatttat tacagatatt ccaaatcgtg ctcaccttta tcaaggacaa acacctcaaa
    26761 cattccgttg caaggacttc atggaccttt atggatctct ttctgatgaa gagaaggaaa
    26821 tcttgacaga tgcatgtaaa atctttgtga tcaaaggaaa agatgtggcc ttggccaaag
    26881 gtgaatactc aaatctgaag attacaaccg taacagattt gaagattgca aaaagtatga
    26941 ttgagaaaga ctagtaaaat gattaatcaa atttatcaac taactaagcc taagtttatc
    27001 aatgtcaaat atcaggaaga ggctattgac caagagaatc atatccttat ccgtcccaac
    27061 tacatggctg tctgtcatgc ggatcagcgt tactatcagg gaaaacgtga tcccaagatt
    27121 ttgaataaaa agcttccaat ggcaatgatt cacgagtcat gtggaaccgt catttctgac
    27181 ccgaccggaa cctacgaggt tggtcaaaaa gttgtcatga ttcccaatca gtctcctatg
    27241 cagagtgatg aagaattcta tgaaaactac atgacaggga cccatttctt gtctagtgga
    27301 tttgatggct ttatgagaga gtttgtttct ctccctaaag atcgtgtggt ggcttatgat
    27361 gctattgaag atacggttgc agccattaca gagtttgtca gtgtgggcat gcacgctatg
    27421 aatcgtctat tgactcttgc tcatagcaag cgggagcgga tcgccgttat tggagatgga
    27481 agtttagctt ttgtggttgc caatattatc aactatactt tgccagaagc agagattgtg
    27541 gttattggtc gtcattggga aaagttggaa ctcttctcat ttgccaaaga atgctatatt
    27601 acggataata ttcctgaaga tttggccttt gaccatgctt ttgaatgttg tggtggtgat
    27661 ggtactggac cagctattaa tgacttgatt cgctacattc gtcctcaggg aacgattctc
    27721 atgatgggag ttagcgaata taaagtcaat ctcaatactc gcgatgcctt agaaaagggc
    27781 ttgattttgg ttgggtcatc tcgttctggt cgcattgatt ttgaaaatgc tatccaaatg
    27841 atggaagtca agaaatttgc caatcgtctt aaaaatatcc tttatctaga agaacctgta
    27901 agagaaatta aagatattca tcgtgtcttt gcaaccgatt taaacacagc ctttaaaaca
    27961 gtgtttaagt gggaagtata agtactggag gttaattgtg gagaaaatca ttaaagaaaa
    28021 aatttcttcc ttacttagtc aagaagagga agtcctcagt gttgaacaac tgggtggaat
    28081 gaccaatcaa aactatttgg ccaaaacaac aaataagcaa tacattgtta aattctttgg
    28141 taaagggaca gaaaagctta tcaatcgaca agatgaaaag tacaatcttg aactactaaa
    28201 ggatttaggc ttagatgtaa aaaattatct ttttgatatt gaagctggta tcaaagtaaa
    28261 tgagtatatc gaatctgcga ttacgcttga ttcaacgtca atcaagacca agttcgacaa
    28321 aattactcca atattacaaa ctattcatac gtctgctaag gaattaagag gagaatttgc
    28381 tccttttgaa gaaatcaaaa aatacgaatc cttgattgaa gaacaaattc cttatgccaa
    28441 ctatgaatct gttagaaatg cagtcttctc cttagagaaa agactggctg acttaggtgt
    28501 tgacagaaaa tcttgtcata tcgatttggt gcctgaaaac tttatcgaat cacctcaagg
    28561 acgactttat ttgattgact gggaatattc atcaatgaat gatccaatgt gggatttggc
    28621 tgccctcttt ttagagtctg aattcacttc ccaagaggaa gaaactttct tatctcacta
    28681 tgagagtgac caaacaccgg tttctcatga aaagattgct atttataaaa ttttacaaga
    28741 tactatttgg agtctatgga ctgtctataa ggaagagcaa ggtgaagatt ttggtgacta
    28801 tggtgtgaat cgttaccaaa gagctattaa aggtttggct tcttatggag gttcagatga
    28861 aaagtaaaaa cggagttcct tttggccttc tctcaggtat tttctggggc ttgggtctaa
    28921 cggttagtgc ttatatcttt tcgattttta cagatttgtc accctttgtg gtggctgcaa
    28981 ctcatgattt tttgagcatc tttatcttac tagcttttct cttggtaaaa gaagggaaag
    29041 ttcgcctctc aattttctta aatattcgca atgtcagtgt tatcatagga gccttgctag
    29101 caggccctat cggtatgcag gccaatcttt atgcagttaa gtatatcgga agttctttag
    29161 cttcatctgt atcggctatt taccctgcga tttcagttct attggctttc ttctttttga
    29221 agcacaagat ttcgaaaaat actgtatttg ggattgtctt gattattgga gggattattg
    29281 cccagaccta taaggttgaa caggttaatt ctttctacat tgggattctt tgtgctttgg
    29341 tttgtgctat tgcatgggga agtgagagtg ttcttagctc ttttgccatg gaaagtgaat
    29401 tgagtgaaat cgaagccctc ttaatccgtc aagtaacttc gttcttgtcc tatcttgtga
    29461 ttgtgctctt ctctcatcag tcatttgttg cagtagccaa tggacaattg ctaggtctca
    29521 tgattgtctt tgtagccttt gatatgattt cctatttggc ttattatatc gctatcaatc
    29581 gcttgcaacc agccaaggct acaggcttga acgtgagcta tgtagtatgg actgtcttgt
    29641 tcgcagctct tttcttggga acatcattag atatgctgac cattatgacg tcacttgtcg
    29701 tcattgctgg agtttatatt attattaaag aataaaggag attcgtgtga aagccattat
    29761 cttagcagcg ggattgggaa ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt
    29821 ggttcaggtt aatcaaaaac ctttgattga ataccaaatt gagtttctca aagaaaaagg
    29881 aatcaatgac atcatcatca tcgttggtta tcttaaagaa caattcgatt atttaaaaga
    29941 aaaatacggt gttcgcctcg ttttcaatga taaatacgct gactacaata acttttactc
    30001 tctctatctt gtaaaagaag aattggccaa cagctatgtt attgatgctg acaattatct
    30061 ctttaaaaat atgttccgca atgatttgac acgttcgact tattttagtg tttatcgtga
    30121 agattgtacc aacgaatggt tcttggtcta tggagatgac tacaaggttc aagacattat
    30181 tgttgatagc aaggcaggtc gcatccttag tggtgtatcc ttctgggatg ctccaactgc
    30241 agaaaagatt gtcagcttta tcgacaaggc ttatgcaagt ggtgaatttg ttgatctcta
    30301 ctgggacaat atggttaagg ataatatcaa agagctagat gtctatgttg aagaattaga
    30361 aggcaatagc atttatgaga tcgatagtgt ccaagactat cgtaaattag aagaaattct
    30421 taaaaacgaa aattaaagat tccaacatct gacaaaatag tcggatgttt tttgattttt
    30481 tacgaataga tagatgagta gaaaaagaaa tggagttatt tatgaaaatc acaaactatg
    30541 aaatctataa gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa gtgctagaat
    30601 acggtgaaaa tgttgatcag gagcttttgt tgggtgatat tgcagatatc tcaggttgcc
    30661 gtaatccagc cgtttttatg gaacgttatt ttcagataga cgatgcgcat ttgtcgaaag
    30721 agtttcaaaa atttccatct ttctctattt tagatgactg ttatccttgg gatttgagtg
    30781 aaatatatga tgcgcctgta cttttatttt acaagggaaa tcttgacctc ctgaaattcc
    30841 cgaaggtagc ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaaa tcagttgaaa
    30901 aagtcattca aggcttggaa aatgaactgg ttattgtcag tggtctggcc aagggcattg
    30961 acacagcagc tcatatggca gctcttcaga atggcggaaa aaccattgca gtgattggaa
    31021 caggactgga tgtgttttat cctaaagcca ataaacgctt gcaagactac atcggcaatg
    31081 accatctggt tctaagtgaa tatggacctg gcgaacaacc tctgaaattt cattttcctg
    31141 cccgtaatcg catcattgct ggactttgtc gtggtgtgat tgtagcagag gctaagatgc
    31201 gttcaggtag tctcattacg tgtgagcgag caatggaaga aggacgcgat gtctttgcta
    31261 ttcctggtag cattttagat ggactatcag acggttgcca tcatttgatt caagaaggag
    31321 caaaattggt caccagtggg caagatgttc ttgcggaatt tgaattttaa aaatgaccta
    31381 agctagaatt ctaagaaaaa atcaatttta agagaaaatg aacccaacat ttccataata
    31441 aaacgcatat tagcaagttt ttaacacttg ataatatgcg ttttttctaa gtggattagt
    31501 agagtagagg atttttctca tataatactc ttcgaaaatc tcttcaaact acgtcagctt
    31561 ccatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc tacaacctca
    31621 aagcagtgct ttgagcaacc tgtggctagc ttcctagttt gcgctttgat tttcattgag
    31681 tataagggaa agtatagtga attgaaataa gatgtgaaca actctatcag gaaagtcaaa
    31741 ttgatttata gaaatatttt agcagccaag gtgcactgtt atagattcaa tacactataa
    31801 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
    31861 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
    31921 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
    31981 taaaaaaatg gtctgaaata gatgatgata cttttcgaaa atctcttcaa actacgtcag
    32041 ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt ttgattttca
    32101 tttactagaa atgaaactga tgagagatat cagtagacat ttgagtcagg atattatgga
    32161 aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt gagtttgtta
    32221 ggattttagc gactagttag ctgggaaagg aagatatttg tgacaaataa taaactgtat
    32281 tcgttgatag aatttagaaa taaaatatat gaagaattag aactttccag aagtgattta
    32341 gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga ttcgactccc
    32401 gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg agtggggctc
    32461 tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt agctattcaa
    32521 attcttgcca gtttaatagc ttcaacactt tatttttatc tttctcccat ttcgtatgct
    32581 agttcggaaa ttgttgctag aacctctccg actatttggg atgttctcat tgcttttgta
    32641 ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat tgttcctggt
    32701 gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc tattgcttct
    32761 gctaatctaa aatttatcat aggctcctct tacctattcc tcatcaattg tagctttatt
    32821 gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta ttttaaagat
    32881 aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt gctgatgatt
    32941 ccgagtttca tctctgcaac gactttagtg agagaaacgt tgaaaaaaga gtcccttaag
    33001 aaatttatat cagagcagtt tcaggggtat aatattttga aaaaaaccta ttctaaaaag
    33061 actcataccc taaagctaac catttcagga aattatttga cagaagaaga actcgatatg
    33121 atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt ttcacaattg
    33181 tctgattcag aacaacttag taaggaagag ctggtggagc atttcttcca gtatatcaag
    33241 gataaggaag caaaagaaaa ggagaaagcc aataaatttg atacagagtc tgaggagcaa
    33301 taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca aaggaagact
    33361 gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac agggttcaaa
    33421 aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg tggctacggc
    33481 aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc atcgtggagt cgcctgctaa
    33541 ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca gtgtcgggca
    33601 tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt atgaaccgca
    33661 atatatcaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag aagctaaaaa
    33721 agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga tttcttggca
    33781 tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct tcaatgaaat
    33841 caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata tggacttggt
    33901 cgatgcccaa caagctcgtc ggatcttgga tcgcttggta gggtattcga tttcgcctat
    33961 tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca ttgcccttaa
    34021 actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat actggacagt
    34081 tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg gagtagatgg
    34141 taaaaagatg aaactgacca gcaataacga agtcaaggaa gtcttgtctc gtctgactag
    34201 taaagacttt tcagtagatc aggtggataa gaaagagcgc aagcgcaatg ctcctttacc
    34261 ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc gtactcgaaa
    34321 aaccatgatg gttgcccaac agctctatga aggaattaat atcggttctg gtgttcaagg
    34381 tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc aaaatgaggc
    34441 ggcaagcttc attacggatc gttttggtag taagtattct aagcacggta gcaaggtcaa
    34501 aaacgcatca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg tctttaatac
    34561 accagaaagc atcgctaagt atctggacaa ggatcagctc aagctatata cccttatctg
    34621 gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg ctgttaaatt
    34681 gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag gttaagtttg atggttatct
    34741 tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg ttggagatgt
    34801 ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg cccgttattc
    34861 tgaagcaaca ctgattaaaa ccttagagga aaatggggtt ggacgtccat caacctacgc
    34921 gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca aacgttttga
    34981 accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc cagatatcgt
    35041 aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag ttggaaaaga
    35101 gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag ttgccaaggc
    35161 tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg actgtgaagt
    35221 gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg cttgtagcaa
    35281 tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg agtgtccaag
    35341 ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctat tctatggttg
    35401 caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc gtgactgtcc
    35461 aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc aggttgtttg
    35521 tagcaaaggc gactacgagg aagaaaagat taaataagag gaggggcccg aaagtaaatt
    35581 tcaggctcct tttggttaga acttgacaaa atacatcatt ttatgcgaaa ctagaagaag
    35641 attattttat actcaatgag aatcaaagag caaattagaa agctagtcgc aggttgctca
    35701 aagcactact ttgaggttga agatggaagc tgacctggtt tgaagagatt ttcgaagagt
    35761 attaactagg agaagttatg cgtattatct atctaattat tggtttttta tcgctgacct
    35821 tggctattgt tggggttgtt ttacccttgt tgcctacaac acctttcctt ttgttgtcta
    35881 ttgcttgttt ctccagaagt tccaagcgat tcgaagattg gctttatcat accaagctct
    35941 atcaagcata tgtagctgat tttcgtgaga ccaagtctat tgcgcgtgaa cgaaagaaaa
    36001 aaatcatcgt ctctatctac gtcttgatgg gaatttctat ttattttgca cctcttttac
    36061 cagtcaaaat cggtctgggt gctttgacca tctttattac ttattatctc ttcaaggtca
    36121 ttccagacaa agaatagtta aaacagtagt tatttgcctt gataaaattg aaagcatatt
    36181 cataacaata tgatataata aaattgaagt aatattcaag gagaatcaaa tgatttacga
    36241 attttgtgct gaaaatgtga ctttacttga aaaagcgatg caggctggag ctcgtcggat
    36301 tgaactctgt gataatctag cagttggtgg gacaacaccc agctatggag tgactaaggc
    36361 agcggttgaa ctggcagcta actacgatac aaccatcatg accatgattc ggccacgtgg
    36421 tggtgacttt gtctataatg acctagaaat tgctatcatg ctagaagaca ttcgtttgac
    36481 tgctcaggct ggaagtcaag gggttgtatt tggagcttta actgctgata aaaagttgga
    36541 taagcctaat ctggaaaagt taattgctgc atcaaaagga atggaaattg tctttcacat
    36601 ggcctttgat gaactaagtg atgaagatca accggaagct attgactggc tcagtcaagc
    36661 cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc gactccttag aaaaacgttt
    36721 tgttcactat cacagaattt tggagtacgc taaaggtaaa attgaaattc taccaggtgg
    36781 ggggattgac cttgaaaacc gtcaaacctt tatcgaccag gtgggggtaa cacaattgca
    36841 tggtactaag gttgtttttt aaaaaataga aaggaactgc tagctttggg tagcagtttt
    36901 cacttatgtt tgaaattttt aaatcctatc aatttaatca agaaaaggct catgattatg
    36961 gttttataga aaatagcgaa gtctggacat atagttgcca gattttgcaa ggtgactttg
    37021 tcatgactgt gtccatcact gctgataatg tgaactttca agtctttgac caagagactg
    37081 gtgacctcta tcctcacgtt tatatggaaa gcatgagggg aagttttgtc ggaaatgtcc
    37141 gtgaggcttg tctggagatt ctttaccaga ttcggaaggc ttgttttgat gtgcaagatt
    37201 ttatctgtca tcagactaag cgtatcatga ctcaagttca ggaaaagtat ggaaaccagt
    37261 tggagtatct gtgggaaaaa tcgcctgata cagctgtatt gcgccatgaa ggcaatcaaa
    37321 agtggtatgc cgtcttgatg aaaatctctt ggaataagct ggaaaagggc agagaaggac
    37381 aagtggaagc agtcaacctc aagcatgacc aagtagctaa tttgctttca caaaagggga
    37441 tttatccagc cttccatatg agcaagcgct actggattag tgtgtccctt gatgatactt
    37501 tatcagatga agaagtactg gaattgatag aaaaaagttg gaacttaacc tctaaaaaat
    37561 gaaatatttt aataattttc atgaactttc aattagctaa atattcttta ctgaagagat
    37621 ttttagaaaa tataggattt accacactag aggaatatgg tgccatcttc aaatacctga
    37681 ttgagaatgt caagacggat cgtcagatca tctattcgcc tcactgtcat gatgacctcg
    37741 gaatggcagt ggcaaatagc cttgctgctg tcaagaatgg tgcaggacgt gttgaaggga
    37801 ctatcaatgg tattagggag cgagctgaaa atgctgcttt ggaagaaatt gcagtggctc
    37861 tcaatattcg ccaagattac taccaagtag aaaccagtat tgtcctaaat gagaccatca
    37921 atacgtcaga aatggtttct cgcttctctg gtattccagt tcctaaaaac aaagccgtcg
    37981 ttggtggcaa taccttctcc cacgaatctg gtattcacca agatggagtc cttaaaaatc
    38041 ctctcactta tgagatcatc acacctgaat tggttggtgt taagattctg cttggaaaat
    38101 tatctggtcg ccatgctttt gttgagaaac tgagagaatt ggccctagat tttacagaag
    38161 aggatatcaa accactcttt gctaagttca aggcactggt cgataagaag caagaaatca
    38221 cagatgcaga tattcgagct ttggtagctg gaaccatggt tgaaaatcca gaaggcttcc
    38281 actttgatga tttacaactt caaactcatg cagataatga cattgaagcg ctcgttagcc
    38341 tagccaatat ggatggtgag aaagtcgaat ttaatgcgac agggcaaggt tccgttgaag
    38401 caatctttaa tgctatcgat aagttcttta accaatctgt tcgtttggtg tcctacacta
    38461 tcgatgcggt aacagatgga atcgataccc aggatcgggt tttggtcact gttgaaaaca
    38521 gagatacaga aaccatcttt aatgcagcag ggcttgattt tgatgtgttg aaggcttctg
    38581 ctattgtcta tataaacgct aatacctttg ttcaaaaaga gaatgcaggt gagatgggac
    38641 gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag aaggctatgg caaagaaaat
    38701 agtagctcta gcaggagacg gaattggccc agaaatcatg gaggttggtt tagaagttct
    38761 ggaggctcta gctgaaaaaa caggttttga ctatgagatt gacagacgac cgttcggagg
    38821 tgcagatatt gatgcagcat gacctccctt acctgatgaa acccttaagg caagtaggga
    38881 agcagatgct atcctactag tagctatcgg tagtcctcag tatgatggag cagtggttcg
    38941 ccctgaacaa ggcctgatgg ctctccgtaa ggaactcaat ctttacgcta atattcgtcc
    39001 tgtaaaaatc tttgacagtc tcaagcattt gtcactactc aaactggaac gaattgctgg
    39061 tgtagacttt gtcgtggtgc gtgaattgac aggcgggatt tactttggag atcatattct
    39121 tgaagagcgc aatgcgcgtg atatcaacga ctatagctat gaggaagtgg agcggattat
    39181 tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc gttactagta tcgataagca
    39241 aaatgttcta gcgacctcaa aactctggcg gaaagtagct gaggaagtcg cacaggattt
    39301 cccagatgta accttggaac atcagctggt agactcagct gctatgctta tgattaccaa
    39361 tcctgctaag tttgatgtta ttgtaacgga gaatcttttt ggagatattt tatctgatga
    39421 atcaagcgtc ttatctggta cacttggggt tatgccatca gccagtcatt ctgaaaatgg
    39481 accaagtctc tatgaaccta ttcacagttc agcacctgat attgcaggtc aaggaattgc
    39541 caatcctatt tccatgattt tatcagtttc catgatgttg agagatagtt tcggacgtta
    39601 tgaggatgca gagcgtatca aacgtgctgt tgagacaagt ctggcggcag gaattttaac
    39661 gagagatata ggaggtcagg cttcaacaaa ggaaatgacg gaagctatta ttgcaaggtt
    39721 atgaagttag acgaaaaaat tactctagtc cttttgattt ggaatgtcat cattttcttg
    39781 atttatggta ttgacaaatc taaggcaagg agaagagttt ggcgcatccc tgagaaaatc
    39841 ttacttattt tagcctttac ttttggtggt tttggtgcct ggctagcagg aatcatcttt
    39901 caccacaaga ctcgaaaatg gtactttaaa atagtttggt ttcttgggat ggtgaccaca
    39961 ctagtagcct tatattttat ttggaggtaa tggatggcag ggtcttcgag ggaatacgct
    40021 gcttgggctc tagcggacta tggttttaag gtcgtgattg caggatcttt cggtgacatt
    40081 cattacaata atgaactcaa taatggcatg ttgccaatcg ttcagcctag agaggttaga
    40141 gagaaactag cccagctaaa accaaccgac caggtaactg tggacttgga acaacaaaaa
    40201 atcatctcac cagttgaaga attcaccttc gagatagata gcgagtggaa acataaactc
    40261 ctaaatagtt tggatgatat cggtattacc ttgcagtatg aagagttgat tgctgcttat
    40321 gaaaaacaac gaccagccta ctggcaggat tagaaaaaat agaaaaggag atatagtaaa
    40381 ctgaaataag atgtaaacaa atgaattgga gcttaacatc catttccagc aattttttag
    40441 aaactacagt ggactattct ggattcaaca cattataaaa ttatgacaaa acacattcac
    40501 aagaaggcta cgacatttta aaaggtgagg gcggatgtat cgtttgccct actaaagttg
    40561 gttacattat catgaccagt gacaaggcag gacttgagcg taagttcgca gccaaagaac
    40621 gtaagcgtaa caaaccaggt gttgttctct gcggtagcat ggatgaactt tgcgctttag
    40681 cgcaactcaa cccagaaatt gaagcattct actaaaaaca ttgggatgaa gatattcttc
    40741 ttggttgtat ccttccttgg aaaccagaag cctttgaaaa actcaaagca tacggggatg
    40801 gccgtgaaga acttattact gatgtacgtg gtactagctg ttttgttatc aagtttggaa
    40861 aagcaggtga acaattggct gccaagcttt gggaagaagg taaaatggtc tacgcctcat
    40921 ctgcttcaat gacaaaacga ttgaaactcg ctatgagcaa ggtgtaatgg tgtctatggt
    40981 cgataaggac ggcaaactca tcccagaaca aggaggagca cgttcaactt caccagctcc
    41041 agttgtgatc cgtaaagggc ttgacattga taaaatcatg atgcacctgt cagatacttt
    41101 taactcatgg gactaccgtc aggttgagta ttattaggat agagaagaag tctagtgtta
    41161 tgagatatta aagctcctaa cactgggctt ttgtttagaa tttcttttct ttttctatag
    41221 gatatggtat tctatgtaga aaatatatgt taataagtaa tgccaatatt taaacatcat
    41281 tagtaaaagg agttagattg atgaataaaa gaaaagttag tttagaagat ttttataaat
    41341 ggtatagtct aaataaagaa gagttattaa ataaggcaac tgttggtgaa aagtttaatg
    41401 ataaattaaa agaagagttt ctccaggaat ggcctttgga taggatttta acaatgtcaa
    41461 tcgatgaata tgtaatagga aagggacagc aaaataagtc tttatgctac gctcttgaga
    41521 agggaaaata caaaaatcta tttcttggaa tttctggtgg ctcagcttca aaatttggta
    41581 tttattggaa taaaaaaaca aacaaatata aagatcaagc taataatgag atttcagagt
    41641 tggatcagcg attttcaaaa ttaaaatcag atttgtatga aattatcaaa gaaggtattc
    41701 gttttaactt tgaaaatcct atttttgata tgaaaagatc aacaaatgaa tttattggtc
    41761 gttctgctat ggtgacaaaa ttactttgta tctatactga gggagatcct ttctttggtg
    41821 taaatattaa tagtcagaaa gaattttgga accactttgt ttctcagaca aatcaaggtg
    41881 gaccttatct gcaaaatcat aaaataattg aactggtgtc caaaacttat cctgagttgg
    41941 agccatcgaa attaggaact atgctttttg agtattctaa gctttttatg gaaaataagg
    42001 aagacaatag tacaatggat tcatcaaaca attttagtca tcaattaact caatctctat
    42061 taaagtctcc aaaccttatc cttcgtggtg ctcctggcac aggaaagact tatcttgcta
    42121 aagaaattgc caaagaatta acggatggta acgaagacca aatcggattt gtacaatttc
    42181 acccatccta tgattatacg gattttgtag aaggtttaag accagtatca aatggggatg
    42241 gagctattga gtttaggcta caggacggta tttttaaaga tttttgtcag aaagcaaaag
    42301 aaacccaatt gattggagga caagataatt ttgatgaggc ttgggattct tacttagaat
    42361 atataaatgt tgctgaagaa aaagaatata taacaaaaac atcttactta tctgttaata
    42421 gtagacaaaa tttgtcagta aattatgata gtggtgttcc aggatggtca ctacctagca
    42481 aatatgttta cgagttgtat aaagataaaa attataataa gcaagaatac tacaaaagtg
    42541 gtggaaaaac tgtcctagaa acattgagaa agagatttgg tttgaaagac tatatttctc
    42601 cagaagaggt tgaaacagac aagaaatttg ttttcatcat cgatgagatc aatcgtgggg
    42661 agatttctaa gatttttggc gaactctttt tttctatcga ccctggctat cgtggtgaaa
    42721 aaggaagtgt ttctacccaa tatgcaaatc tacacgaaac tgatgaaaag ttctatatcc
    42781 ccgaaaatgt ttacatcatc ggaactatga atgatattga tcgttcagtg gatacctttg
    42841 attttgctat gcgtcgtcgt tttcgttttg ttgaagttac tgccgagggt caagttggca
    42901 tgttggataa agagctgaat atccatgcag aagaagcaaa aattcgtcta agaaacttga
    42961 acgctgctat cgaaaatgtt caggaattaa acagtcatta tcatattgga ccaagttatt
    43021 ttcttaagtt gaaggatgta gattttgact atgaattact ctggtctgat tatattaagc
    43081 ctctcctaga agactacttg cgaggttctt atgatgaggt tgaaactttg gaaactttga
    43141 aaaaagcatt tgaactgaca aataatgagc aaaaagatca ggcagtagct gatgacaatg
    43201 aaggtgatga aaacgatgat gcggattact gataatcaac acaagattat taaagaaaaa
    43261 tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt ggaaagtcta
    43321 tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc tgatttggat
    43381 aaggatcaaa agatttttga aacagtcaat cagaaaatca agacagggaa cgtgattggt
    43441 tttcttggat atggtcagga aagattaacg atttcctcac gattttctga tgagagtaat
    43501 gaccattttt tgcattatct cttaaacaag gttctttata tcaatctcac tagtttagat
    43561 gttgctttgt ctcgtgaaga gaggctttat caacttttga tgtatctctt ccccaagtat
    43621 ctacaagctg ctattcgaaa aggtctttat aaggaatatc atcgattttc tcataacgac
    43681 agtaatgtta agggagtgat tgttgtaaga aaccatctca agaaaaatct tcctttcacg
    43741 ggaaatattg cctacacaac gagagagttc acctatgata atcccctcat gcagttggtc
    43801 cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt actagataat
    43861 ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc ttataaacta
    43921 gctgatcgtg ctaagattac tcggagaaat caatctaaac ctatacgtca tgcatacttt
    43981 cacgagtaca gaaacttaca agaactttgt ctgatgatcc taaaccaaga aaagcacggt
    44041 ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg gctttgggaa
    44101 gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa ggataagacg
    44161 gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt ttatgacaga
    44221 gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga aaaaggaatc
    44281 aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc tgagaaggct
    44341 ggacttgttt ttccgagcaa ggacaaggtc attgataatg agataggaaa cctagcaggt
    44401 tatggagctt tgttgaagaa atggtctatc caaattcctc agaagtcttc atcttatagt
    44461 gcattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat tgatgaagaa
    44521 gtggggagaa aataatttcc cctctttctt ttatttttaa cacaagcaaa atccgaacaa
    44581 tatattttaa ttcataaaat aatttgacaa aaactgtact ttggtttata ataaattaag
    44641 gaaacgtcgg aaaaggcgta gtgatgcgag agcataggta ggtcattaca aaagaaacga
    44701 gacatcgata tgttaaatga atttccaatt tttgattacg aagatattca attgattcca
    44761 aataaatgtg tcattaaaag ccgtgcagaa gcggatacaa gtgtcacttt aggaaatcac
    44821 acctttaaac tacctgttgt gccagcgaat atgcagacga ttttggatga aaatgtagca
    44881 gagcaactgg ctaaaggtgg ttacttctac attatgcacc gttttgatga ggcaggacgc
    44941 attcctttta ttaaacgaat gcacgatcaa gggctcattg cttccatatc tgtcggtgtt
    45001 aaggattatg agtatgattt tgttagccag ctcaaggctg atgctcctga gtatatcact
    45061 attgatattg ctcatggtca tgcggatagc gtgatttcta tgattcaaca catcaagaaa
    45121 gaattgccag atacctttgt cattgctgga aatgtgggaa caccagaagc tgtgcgtgaa
    45181 ttggaaaatg ctggtgcaga tgctactaag gtcggaatcg gtcctggtaa ggtttgtatc
    45241 accaaggtta agactggttt tggtacaggt ggttggcagt tggctgctct acgctggtgt
    45301 gccaaggctg cgcgtaaacc gattatcgct gatggaggaa ttcgtactca cggtgatatt
    45361 gccaagtcta tccgcttcgg tgctagcatg atcatgattg gttccctctt tgcaggacac
    45421 attgaaagtc cagggaaaac gattgaagtc gatggtgaac agttcaaaga atattatggt
    45481 tcagcctcac aatatcagaa aggtgcttac aaaaatgtgg aaggcaaacg tatcttgctt
    45541 cctgctaaag gtcatctgca agacacttta actgagatgg aacaagacct tcaaagtgct
    45601 atttcttatg caggtggacg tcaggttgct gaccttaaac acgttgatta tgtgatcgtg
    45661 aaaaactcca tctggaatgg ggatgcttcc cactaagacg gggtctttga ccaaaaaact
    45721 tgttattaga gcaaatttct gttataataa aacaagtttc cacccttagt gtaatggata
    45781 tcacgtaaga ttccggttct tgagatgggg gttcgattcc ctcagggtgg atgtaaacat
    45841 cctaaaaagc ctttaatagg gcttttttct ttatcctgac ccaaatttgc cgctaaaact
    45901 gagaatctct gtctaaagaa ttcccaaatg ctttccagtc ccgttttaga gtgactcagg
    45961 gggctttttt tgatataata aaaaggacta ttatcagtta gaaagaagtt ggtatgaaag
    46021 aattacaaac tgtactaaag aatcattttg aaatcgaatt tgcagacaaa aagttactgg
    46081 aaactgcctt tactcatacg agttatgcca atgagcaccg cctcttaaaa atttcacaca
    46141 atgaacgctt ggaattttta ggagacgctg ttctacagtt attgatttca gaatatctat
    46201 ataaaaaata tcctaaaaag cctgaaggtg acctatcaaa actccgtgct atgattgtcc
    46261 gtgaggagag tttagctggt tttgcgcgtg attgccagtt tgaccagttt atcaagttgg
    46321 gtaaagggga agaaaaatct ggtggtcgca atcgtgacac cattcttggt gatgcctttg
    46381 aagcctttct tggtgccctt cttttggata aggatgtggc aaaggtcaag gaatttatct
    46441 accaagttat gattcctaag gtagaagcag gcgaatttga gatgattaca gactataaaa
    46501 cccatctcca agagttgctt caggtcaatg gtgatgtggc tattcgttat caagtgattt
    46561 ctgaaacagg gcctgctcac gataaggtct ttgatgtaga agttcttgtt gaaggtaaga
    46621 gcatcggtca aggccaaggt cgttctaaga aattagcaga gcaggaagct gccaaaaatg
    46681 ccgttgagaa agggctggat tcatgtattt aaaggaaatc gaaattcagg ggttcaagtc
    46741 ttttgctgat aagaccaagg tcgtttttga ccaaggtgtg acggcagttg ttggacccaa
    46801 tggatctgga aagtccaata ttacagaaag tctgcgttgg gctttggggg agtctagtgt
    46861 caagagtctc cgtgggggca agatgccgga tgtcatcttt gctggaacag aaagtcgcaa
    46921 accgctcaat tatgcttctg tagttgtgac tctggataat catgacggat ttatcaagga
    46981 tgcaggtcaa gaaatcaggg tggaacgcca tatctatcgt agtggagata gcgaatacaa
    47041 gattgacggc aagaaagtcc gtctgcgtga tattcatgac ctcttcttgg atactggatt
    47101 gggacgagat tccttctcta ttatttccca agggaaggtt gaggagattt ttaattccaa
    47161 gcctgaggaa cgacgagcta tttttgaaga agctgctgga gttttaaaat acaagactcg
    47221 cagaaaagaa accgagagta aactgcagca aactcaggat aatctggacc gcttagagga
    47281 cattatctac gagttggata atcaaatcaa gcctcttgag aagcaagctg agaatgcccg
    47341 taagttttta gacttggaag gacaacgtaa ggctatttat ttagacgttc tggttgctca
    47401 aatcaaggaa aataaggcag aactagagtc gacagaagaa gagttggctc aggttcaaga
    47461 actcttgatg agttattacc aaaagcgtga aaaattagaa gaagaaaatc aaactcttaa
    47521 aaagcaacgc caagatttac aggctgaaat ggccaaagac caaggcagtt tgatggactt
    47581 gactagtctg attagtgatt tagaaagaaa attagcccta tcgaaactgg agtccgagca
    47641 agtggccctg aatcaacagg aggcacaagc tcgtttggct gctttggagg ataagagaaa
    47701 ttcactcagc aaagaaaagt atgataaaga aagctcttta gctctgttag agggaaatct
    47761 agtccaaaat aatcaaaaac tcaatcgttt agaagctgaa ttgctggctt tctcagacga
    47821 tcctgatcag atgattgagc tcttacgtga acgctttgta gctcttttac aagaagaagc
    47881 ggatgtctca aaccagttga cccgtattga gaatgagttg gaaaatagtc gtcagctttc
    47941 tcaaaaacaa gcagatcaac tagaaaagct gaaagagcaa ttagctacag ctaaagagaa
    48001 ggctagtcag caaaaagacg agcttgaaac tgccaaggtg caggttcaga aattattggc
    48061 tgactatcaa gctattgcca aggagcaaga ggagcagaaa acttcctatc aagctcaaca
    48121 aagtcaactc tttgaccgtc tggatagtct caaaaacaag caggccagag ctcaaagttt
    48181 ggaaaatatc ctgagaaatc atagtaactt ttatgcaggt gttaagagtg ttctccaaga
    48241 aaaagatcgc ctaggtggga ttattggtgc agtcagtgag catctgacct ttgatgttta
    48301 ttatcaaact gccctagaga ttgccttagg ggcaagtagc cagcatatca tcgtagaaga
    48361 tgaagagtcg gcaaccaaag ctattgattt cctcaaacga aacagagtcg gtcgtgcaac
    48421 ctttcttcct ttgaccacta ttaaggcgcg tacgatttct agtcagaacc aagatgctat
    48481 cgctgtaagc ccaggtttcc ttgggatggc agatgagttg gtgacttttg atactagact
    48541 ggaagccatt ttcaagaact tgctagctac gacggctatc tttgataccg tagaacatgc
    48601 gcgtgaagct gctcgacaag ttcgttatca ggttcgtatg gtgacattgg atgggacaga
    48661 attacgcacg ggtggttcct atgcgggtgg tgccaatcgc caaaataaca gtattttcat
    48721 caagccagaa ctggagcaat tacaaaaaga aattgctgca gatgaagcaa gcttgggttc
    48781 agaagaagcg gctttgaaga ccttgcaaga ccagatggct gcattgacag aaagattaga
    48841 agccatcaaa tctcaaggag agcaggcacg tattcaggag caaggcttgt ccctcgctta
    48901 tcagcaaact agtcagcaag ttgaagaact ggaaactctt tggaaactcc aagaagagga
    48961 aatagatcgt ctttctgagg gagattggca agcggataag gaaaaatgtc aagagagcct
    49021 tgctactatc gccagtgaaa agcaaaatct ggaagctgag attgaagaaa ttaagtctaa
    49081 taaaaacgcc atccaagaac gctatcaaaa tttgcaggaa gaggtggcgc aagctcgctt
    49141 gcttaagaca gaactgcaag ggcaaaaacg ttatgaagta gctgatattg agcgtttagg
    49201 caaggaattg gacaatctta atatcgaaca agaagaaatt cagcgcatgc tccaagaaaa
    49261 agttgacaat cttgagaagg ttgatacaga attgctcagt caacaggcgg aagaatccaa
    49321 aactcagaaa acaaatctcc aacaaggttt gattcgcaag cagtttgagt tggatgatat
    49381 agaaggtcaa ctggatgata ttgccagtca cttggatcaa gctcgccagc agaatgagga
    49441 gtggattcgc aagcaaacac gtgctgaagc caagaaagaa aaggtcagcg agcgcttgcg
    49501 ccatctacaa aatcaattaa cagaccagta ccagattagc tatactgaag cactagaaaa
    49561 ggcacatgaa ttggaaaacc tcaatctggc agagcaagag gtgcaggatt tagagaaggc
    49621 tattcgctca ttgggacctg tcaacttgga agctattgac cagtacgaag aagttcacaa
    49681 ccgtctggac tttctaaata gtcagcgaga tgatattttg tcagcgaaaa atctgctcct
    49741 tgaaaccatt acagagatga atgatgaggt caaggaacgc tttaaatcaa cctttgaagc
    49801 tattcgtgag tcctttaaag tgaccttcaa gcagatgttt ggcggaggtc aggcagactt
    49861 gatattgact gagggcgacc ttttaacagc tggtgtggag atttctgttc aacctccagg
    49921 taagaaaatc cagtcgctta acctcatgag tggtggtgaa aaagctctat cggctcttgc
    49981 cttgcttttc tccattattc gtgtcaagac cattcctttt gtcatcttgg atgaggtgga
    50041 agctgcgctg gatgaagcca atgttaaacg ttttggggat tacctcaacc gctttgacaa
    50101 ggacagccag tttatcgttg taacccaccg taagggaacc atggcagcgg ctgattccat
    50161 ctatggagtg accatgcaag aatcgggtgt ttcaaagatt gtttcagtta agttaaaaga
    50221 tttagaaagt attgaaggat gacaattaaa ctagtagcaa cggatatgga cggaaccttc
    50281 ctagatggga atggacgctt tgatatggat cgtctcaagt ctctcttggc ttcctacaag
    50341 gaaaaaggga tttactttgc ggtggcttcg ggtcggggat ttctgtctct ggaaaaatta
    50401 tttgctgatg ttcgtgatga cattattttc atcgcggaaa atggcagttt ggtagagtat
    50461 caaggtcagg acttgtatga agcgactatg tctcgtgact tttatctggc aacttttgaa
    50521 aagctgaaaa cgtcacctta tgtagatatc aataaactgc tcttgacggg taagaagggt
    50581 tcatatgttc tagatacggt tgatgagacc tatttgaaag tgagtcagca ttataatgaa
    50641 aatatccaaa aagtagcgag tttggaagat atcacagatg acattttcaa atttacaacc
    50701 aacttcacag aagaaacgct agaagctggt gaagcttggg ttaatgaaca tgtccctggt
    50761 gttaaggcca tgacaactgg ctttgaatct attgatattg ttctggacta tgtcgataag
    50821 ggtgtagcta ttgttgaatt agctaaaaaa cttggtatca caatggatca ggtcatggct
    50881 tttggagaca atcttaatga cttacatatg atgcaggttg tgggacatcc tgtagctcct
    50941 gaaaatgcac gacctgaaat tttagaatta gcaaagactg tgattggtca ccataaggaa
    51001 cggtcggtta tagcttatat ggagggctta taatggcaga tataaaattg attgcattgg
    51061 acttggacgg gaccttgctg actactgata aaaggctgac ggatcgtacc aaggaaacct
    51121 tgaaagctgc gcgtgatcgt ggtatcaagg tcgtattgac aactggtcgt cccttaaaag
    51181 ccatggattt ctttctccat gagttaggga ctgacggtca ggaagatgag tataccatta
    51241 cttttaatgg tggattagtt cagaaaaata caggagaaat ccttgataaa acagtctttt
    51301 catatgatga tgtggcacgt ttgtatgaag aaacagagaa attatcactg cctcttgatg
    51361 ccatctcaga aggaacagtt tatcaaatcc aatcggacca agaaagtctt tatgccaaat
    51421 tcaatccagc tttgaccttt gttccagtgg actttgaaga cttatctagt caaatgacct
    51481 acaacaaatg cgtgactgcc tttgctcaag aacccttgga tgcagccatt cagaagattt
    51541 ctccagaatt gtttgaccaa tatgaaatct ttaaatcacg tgaaatgttg ctagaatggt
    51601 caccaaagaa tgttcataaa gcaacaggtt tggcaaaact aatcagccat cttggaatcg
    51661 accaaagtca agtgatggct tgtggtgacg aggccaatga cctctctatg attgaatggg
    51721 caggtcttgg tgttgctatg caaaacgctg ttcctgaagt aaaggcagcc gcaaatgtag
    51781 tgacgccgat gaccaacgat gaggaagctg tcgcctgggc tatcgaagaa tatgtgctaa
    51841 aggagaacta agatatggga ttgtttgacc gtctattcgg aaaaaaagaa gaacctaaaa
    51901 tcgaagaagt tgtaaaagaa gctctggaaa atcttgattt gtctgaagat gttgatccta
    51961 ccttcacaga agttgaggaa gtttctcagg aagaagcaga ggttgaaatt gttgaacaag
    52021 ctgtgttcca agaagaggaa atccaagaca cagttgaaga aagtctggat ttagagccag
    52081 ttgtagaagt ttctcaaaaa gaagtcgaag aatttccaca ctcagaagaa gggaatactg
    52141 agtttctaga gactatagaa gaaaataatt ctgaagttct tgaaccagaa aggcctcaag
    52201 cagaagaaac cgttcaggaa aaatatgacc gcagtcttaa gaaaactcgt acaggtttcg
    52261 gtgcccgctt gaatgccttc tttgctaact tccgctctgt tgacgaagaa tttttcgagg
    52321 aactggaaga actgctgatt atgagtgatg ttggtgtcca agtcgcttct aacttaacgg
    52381 aggaactacg ttacgaagcc aagcttgaaa atgccaagaa acctgatgca cttcgtcgtg
    52441 tcatcattga gaaattggtt gagctttatg aaaaggatgg tagctacgat gaaagcatcc
    52501 acttccaaga taacttgaca gttatgctct ttgttggtgt gaatggtgtt gggaaaacaa
    52561 cttctatcgg aaaactagcc caccgctaca aacaagctgg taagaaggtc atgctggttg
    52621 cagcagatac cttccgtgcg ggtgcagtag ctcagctagc tgaatggggc cgacgagtag
    52681 atgttccagt agtaactgga cctgaaaaag ctgatccagc cagcgtggtc tttgatggta
    52741 tggaacgtgc cgtggctgaa ggtatcgata ttctcatgat tgatactgct ggtcgtctgc
    52801 aaaataagga taaccttatg gctgagttgg aaaagattgg tcgtattatc aaacgtgttg
    52861 tgccagaagc accacatgaa accttcttgg cacttgatgc atcaacaggt caaaatgccc
    52921 tagtacaggc caaagaattt tcgaaaatca cacctttaac gggaattgtt ttgactaaga
    52981 ttgatggaac tgctcgagga ggtgtggttc tagccattcg tgaagaactc aatattcctg
    53041 taaaattgat tggttttggt gaaaaaatcg atgatattgg agagtttaac tcagaaaact
    53101 ttatgaaagg tctcttggaa ggtttaatct aatcagaagc aaaaatcctg caaggcataa
    53161 acttgcagga aattttttta ttctaagcga ccatcttgac gataggtgat atctggttgc
    53221 caagtccatt tggcaccgaa tttttcaagt aggtcaaagc tggcttgagg tcccatgctt
    53281 ccagctttat agtcatgaag tggggcacca ttttcagccc agagcttttc aatacggtca
    53341 atcaacttcc atgacgcaca aacttcatcc cagtggctaa agttagttga gttgttattt
    53401 aggacatcat aaatcaattt ttcgtatggt tctggagaag caccagttgc agtcgcatct
    53461 gtacggtaat caagtgagtt aggagccaag ttaaattctt ctcctacttg cttcccattt
    53521 aggctaagag agaagccttc tgttggttga atatagatgg tcaaaatatt tggagcaagt
    53581 ggttctccaa agatagaatc catttgttta aagacgatgt tgacatgagt tcctttttca
    53641 gtcagtcgtt tacctgtacg gaaaaagaaa ggaacaccac ggaatcgatc gctgtctaca
    53701 aagaaggcac cagatgtaaa ggtttcagtt gttgattctg gattcacatt tggctcgcta
    53761 cgataagaga tgtatttcat gccatcaatc ttaccagagc ggtattgccc acggataaag
    53821 tgttctttga gttcttcatc agttggatga tagaggtttt taaagacctt aatcttttca
    53881 gcacgaatct cgtcttttgt gaagcttgct ggtttgtcca tggcgaggag cgaaagaagt
    53941 tgtagagtgt ggttttggac catgtcacgg agggcaccgg attggtcata gtagccacca
    54001 cgttcttcta cacccaagcg ctccgcaaag gtaatttgaa cattgtcgat aaaatccttg
    54061 ttccaaacgt tttcaaaaat caagtttgca aagcgaactg caaagatgct ttggatcatt
    54121 tccttaccaa gataatggtc gatacggaaa atttgttctt cgtcaaatgt tgctaggagt
    54181 tcgtcattca acttgtttgc agttgcgtaa tctgtaccaa atggtttttc aacgatcaag
    54241 cgctcaaaac ctttgccatc gacaatgttt tcagatttga ggtgtttggc aatggttcca
    54301 aagaactgag gtgccataga caagaagaag agcttattgt gttcagcttg gtatttttca
    54361 ttaagctcag cttgtaattg acgcaaagca atataatgtt ccgaatcatt gacatcatgg
    54421 ctttgatagt agaagtggct agcaaattct tgggcttgct cggtactatc tgccaaatca
    54481 aggatggact cgacaactac agattcaaaa tattccttac tccaaggtct acgggcagtt
    54541 ccaataacgg caaagtgctt ggaaagattg ccggatttat atagtctaaa aagggaaggg
    54601 tagagcttgc gtttagccag gtctccactc gcaccgaaaa ttgtaacaat aaccttagat
    54661 gacatctagc tacctaattt ctatttttat tcctagtctt gctaggtatg aggaaacctc
    54721 atttcataaa cttaattcta acataatttt ccgaaaaatc aaaaattcca atacgaggta
    54781 gaaaaactgc aaggaaatcc ttacagtttg agtttagacg tttaagacct tatctaagaa
    54841 ctctttcaga cgagggtgtt gtgggttatc aaagatttgg tcaggtgttc cgtcttcaag
    54901 gaactcgcca tctgcagtaa agataacgcg gttggcaacc tgacgagcaa atcccatctc
    54961 atgggttacg ataatcatgg tcatgccttg ctcagccaat tccttcataa cgttaagtac
    55021 gtctccaacc atctcagggt caagggcaga agttggttca tcgaagagca tgatgtctgg
    55081 attcattgct aggccacgag ctatggccac acgttgtttt tgaccacctg ataggctatc
    55141 tggattggca ttagctttat ctgctagtcc aaccttttca agcaactcca ttcccaattt
    55201 ctcagcttct tccttagtca tcaacttgtg ctcaatagga gcaaaggtga tgttgtccaa
    55261 tacagacata tgagggaaga ggttgaagtg ttggaatacc atgccgatat tttcacggac
    55321 gtggtcaaca ttggttgttt tttcagttaa atcatagccg ttcacagtga tgtgaccgct
    55381 agtgacttct tctaaaagat tgaggctacg gaggaaagtt gacttaccag aacctgaagg
    55441 accgatgata caaacaacat ctccttcata gaacttagtc gtaattcctt ttaggacttc
    55501 attttttcca tagtgcttgt gtaaatcatt tacatcaatt tttaattttg ccattaacga
    55561 atcctctttt ctaagcgttt cgctagtcta gtcaaaagtg tgataattac aagatagaag
    55621 atagcaagga ttgcatacat cttgaaactt tggtagttac gagcaatgat aatcttacca
    55681 gtttggaaga gttcaaccaa accgatagca gatacgatag ttgtatcttt aagagcgata
    55741 acgaattggt tgacaaagtt tggcaacatc aatttagttg cttgtggcaa gataatctta
    55801 cgcatggttt ttccataaga gatacccaag cttcggctgg cttccatttg gccaactgga
    55861 acggcctgaa taccaccacg aacgatttca gcgatataag cagccgcatt gagtgagagg
    55921 gcaatggttc cagctacaaa gtcgttaatt gggctttgtt ggcctgtgat agactcgatg
    55981 aagtttggaa ttccccagaa gatgaaggct gcaagaatca tcaatggaat accacgaata
    56041 acgtcaacga aaatctcaga gatgacgcga agagatttgt atgggctaac gctaaacata
    56101 ccgaagataa ttccgatgac aatggcaata gcaaatgaga taagagctag agcaagagtg
    56161 ataccaagac cgctaaggag ttgtttgtag ttgttttgaa gcaagcccca gagcgttgtt
    56221 tcgtcaacag tacttgttga agcagttgaa gattcgctag ctaggtattt gtcaagaatc
    56281 ttttggaatt caccgtttgc tttaaggttt gcaagtccgt tgttgaacat ttcaatcagt
    56341 tctggatttg ctcctttttt aacggcaaag gctgtttcac cgattggagt tccagagatt
    56401 ggagttttca atttttgacc ttggctgata gaatatttga gaacaggttc atcatccata
    56461 acggcatcaa tggcaccagt gtttaaactg tcatacattg aagaaccatc agcaaaggtt
    56521 ttgattttgt agccgtattt gctttgattt tctgttagga aggtttgaga agcagttccg
    56581 tttttaacac cgactgtctt tccttttaga tcttcataag aagcaatatt acttgattct
    56641 ttgacaccaa gaatggtatt agcagtgtag tatgattctg agaagtcaaa agttgcctta
    56701 cgagcatctg tgacagacat accagcgatg ataccatcgg cttgaccagc ttggacagca
    56761 ctgatagcag catcaaaacc agggttggtg atttcaattt caaaaccttg gtctttagcg
    56821 attgccttaa tcaattccat atcaatacca gtgtattgat tgcttgaatt ttggaaaaca
    56881 aaaggtgcaa aagaagaatc gctggcaatg atatatttag ccttaacagg aatagctttt
    56941 aatcctgcga gagtagttgt agttggcact gctgaagatg atgaagcagt ccatttcttg
    57001 ataattttat caagactacc atcttttttc atttcagcca aggcttggtt aaattcagta
    57061 accaggtgct cgtatttact tccttttttc acaccgaaag caaaacttcc tacagcttca
    57121 ccatccattt caatatggag gtcttgacct tggttaatgg catattcgat aacaggtttg
    57181 tcatccatca tggcatcgat ggcaccagca ctcaagctgt tgttcattaa atcaccagtg
    57241 tcaaatgttt taatagtaaa gccgtattta tctttgattg tttcaaggaa acgttgagcg
    57301 gcagttccgt ttttaacacc aacggttttg ccagttaatt ggtcgtactt gctaattttg
    57361 tgtgactttg tagtagcaat gacaactttt gtatcatagt aagtatcaga catggtgaag
    57421 actttttcac gttctttagt ctttgtcatc cctgccatga tagcgtcggc ttgcccagct
    57481 tgaaccgcat tgactgctgc gtcaaatcca ggataggaca tctgaatgtt ccagccttta
    57541 atctcagcga ctttgttaat aatgtcaaca tcaattcctt tataagtttg atctgaatct
    57601 ttaaactcaa aaggtgcata ggcggtatca gaaacaatct taatcgtttc tgctttggca
    57661 atacctaatg agaaaattgg gaataaaatt agcaaaaatg ctagaaattt tttcttcatt
    57721 tttagtctcc ttttccgaat attctctcat tatatcagaa aaagtaaaaa aaggcaaatt
    57781 tttatatttt tcgtgtcaga aaatataaca ttgatttttt ccttttcttg aattgctatt
    57841 aaaaagtgct ataataatag tatatataga agaaaagagg acggggatat gaagaacaaa
    57901 agaatattta aagacttcca agcttcaaaa atgagtttaa acatttacac aagccccttg
    57961 ttagccattg tttttgtctt cataggagag tttgtggctt ttactttgta tggtattggc
    58021 ttgttagctc tcatcggact tgctagaaat tttggagagg ctggtcaaaa tcttgcaacc
    58081 tacttgcaga ccttgcatca gagcttgacg gataaaacaa gtgactttcg tttaatttta
    58141 ggattactgg cctttggttt tattcttaac actgtgttca gatggacaag aaaagttgag
    58201 aaaagaccta ttcgaacctt gggattttat agagagaatt gcctcagcaa tcttctgaaa
    58261 ggatttagtc taggtctggc actttttctt ctgaccttgt taggtttggt ggtcttaggt
    58321 caatatcgtt tggaatccat tcacttgaat ccttattctc ttgcctttgt cgtctttact
    58381 atcccatttt ggattttaca ggggacagca gaagaagtgg tggcccgtgc ttggctactt
    58441 cctcaattgg cctcaagaac caatctaaaa ctagctattc ttatatctag cctgttcttt
    58501 accctgcttc atatgggcaa ttctggcctc acccctctat ctctagtaaa tctcttttta
    58561 ttcggagttg ccatggctct ttaccttctc aaaactgata cagtttgggg tgttgcaggt
    58621 attcatggtg cttggaattt tgctcagggt aatctctttg ggattttagt tagtggtcaa
    58681 ccgtcaggaa cgtctctgat gaccttttta ccacaaggca atcaagattg gttatcaggt
    58741 ggttcttttg gcatagaagg ttccattatg acaagtctgg tattactact gctgattgtc
    58801 tatcttgcta ataaattaaa gaaagaaaat gaaaggatgt gacttcggtc cgtccttttc
    58861 ttcgtgaaaa tactataagt atgctaaaat aggaatagca catggagaga ggattcttat
    58921 gatcaatcac attacagata atcaatttaa actagtatca aaatatcaac catcaggaga
    58981 tcaaccccaa gctatcgagc agttggtgga taacattgag gggggagaaa aagctcagat
    59041 tctgatgggg gcgactggaa cagggaagac ctatactatg agtcaggtca tttctaaagt
    59101 caataaacca actctggtta ttgcccacaa taaaactctg gctggtcagc tctatgggga
    59161 gtttaaggaa tttttccctg aaaatgcagt tgagtatttc gtatcctact atgattatta
    59221 ccagccagag gcctatgtcc cttctagcga tacctatatt gagaaggata gttctgtcaa
    59281 tgacgagatt gacaagcttc gccactcagc tacctcagcc cttttggagc gtaatgatgt
    59341 tattgtcgtg gcctcagtct cttgtatcta tggtttgggt tcgcccaagg aatacgctga
    59401 tagtgtcgtt agtctccgtc ctggtctaga gatttctcgt gataaactct tgaatgactt
    59461 ggtcgatatt cagtttgaac gcaatgatat tgatttccaa cgcggaagat ttcgcgttcg
    59521 tggggatgtg gtagagattt tcccagcttc ccgagatgaa catgcctttc gagtagaatt
    59581 ttttggagac gaaattgacc gtattcgtga agttgaggct ctgacaggtc aggtgttggg
    59641 agaagtggat catttagcga ttttcccagc gacacacttt gtgaccaatg acgaccacat
    59701 ggaagttgcc attgcaaaga ttcaggccga gttggaagaa caattagctg tctttgaaaa
    59761 ggaaggtaaa ctgcttgaag cccagcgttt gaaacagcgg acagagtatg atatcgaaat
    59821 gttgcgtgag atgggctata ccaatggggt tgaaaattat tctcgccaca tggatggacg
    59881 gagcgaagga gagcctcctt atacgcttct cgacttcttc ccagatgatt tcttgattat
    59941 gattgacgag agtcatatga ccatagggca aatcaagggc atgtacaatg gagaccgttc
    60001 gcgtaaagaa atgctggtta attatggttt ccgtttgccg tctgctttgg acaatcgtcc
    60061 tctccgtcgg gaggagtttg agagtcacgt tcatcagatt gtttacgttt cagcgacacc
    60121 tggtgactat gaaaatgaac agaccgagac agtgattgag caaatcattc gtccaacggg
    60181 actcttggat ccagaggtgg aagtccgtcc gactatggga cagattgatg acctcttggg
    60241 tgaaatcaat gcccgcgttg aaaaaaatga gcgtaccttt atcacaactt tgaccaagaa
    60301 aatggcagag gacttgaccg actacttcaa ggaaatgggt atcaaggtta agtacatgca
    60361 ctcggatatc aagaccttgg aacggacgga gattatccgt gacctgcgct tgggtgtctt
    60421 tgatgtcttg gtcggaatta acctgctccg tgaaggaatt gacgttcctg aagtgagcct
    60481 cgtagctatt ctcgatgctg acaaggaagg tttccttcgc aacgaacgtg gactcatcca
    60541 gactattgga cgtgctgctc gtaacagtga aggccatgtc atcatgtatg cagacacggt
    60601 tacccagtct atgcaacgtg ctatcgatga aactgcccgc cgtcggaaaa ttcagatggc
    60661 ctataatgaa gagcatggta tcgtaccaca gacaatcaag aaagaaatcc gtgacctgat
    60721 tgctgtgacc aaggcagttg ctaaggaaga ggacaaggaa gtcgacatca atagcctcaa
    60781 caaacaagag cgcaaagaac tcgtcaagaa actagaaaaa caaatgcaag aagccgtcga
    60841 agtacttgac tttgaactgg cggctcagat ccgtgatatg atgttggaag tcaaggcctt
    60901 ggattagggg aatagtatga tttatttaag aaagttaaag agagaagatt tgatgtcttt
    60961 atgggaaatg gcttattcac aacttaatcc agtttggaaa cagtatgatg ctccctatta
    61021 tgatgattat cagtattttt caaattttaa agaattcgaa ctacaaaaat cagaatccat
    61081 tttaagcaac tcaaatcgcc ttggtatttt tgttgatgat aaactagttg ggactgtttc
    61141 gcgttattgg gtatgtaaac aaacaagatg gatggaattg ggaattggta tttatgataa
    61201 aaaattctgg aacactggta ttgggaaagt tgctatgttg cagtggatag ataggacgtt
    61261 tcaggattac ttggagttgg agcatctggg tttgacaact tggtcaggga atcttggtat
    61321 gatgaaactt gctgaaaaat taagaatgaa aaaagaagct catattccaa aagttcgtta
    61381 ttatcaaggt aaatattttg atagtattaa atatggtatt ttgagagaag actgggagaa
    61441 aacaaatgac ggttattatc aaatcaatgg aaactcctga agagatagaa ggtaagcccc
    61501 ttgttcactg gcaaacgtgg agagaggctt atgatggcct tttgcctgca gaatttcagg
    61561 agacaatgac attagaaaga tgtcgattct ttagtcaaaa gtatccagaa aatacattga
    61621 ttgcgatgga tggtatgaag gtagttggtt ttatcagtta tggcaacttt cgtgatgaga
    61681 ctattcaagc tggcgaaatt attgctttat atgttttaaa agactattat ggaaaaggta
    61741 tcgcacaaaa gttaataaaa gcagctttga ttgctcttaa tcatttttct gaaattttct
    61801 tatgggtatt gaaagataat aagcgcgcaa ttgctttcta tcaaaaaatg ggctttactt
    61861 ttgatgaaca agaaaagata cttgaacttg gaaagcccat aaaggaaaaa cggatggtat
    61921 tctattctaa ataattttaa aaagtagaag ctaatggtac tggtatcaag tctaaaaatt
    61981 taataaatta gaaagtgagt aaatttatgt ctcgagcaca attaacgatt ttaacaaata
    62041 tttgtctgat tgaagatctc gaagctcagc gcgtggtgat gcagtatcgc gctcctgaaa
    62101 ctaatcgctg gtctggttat gcctttccag gaggccatgt agaaaatggc gaatctttcg
    62161 cagagtctgt cattcgtgaa atctatgaag aaacagggtt gactatccaa aatcctcaac
    62221 ttgtcggcat taaaaattgg ccactagata caggtgggcg ctatattgtc gtttgttata
    62281 aggcaactga gttctctggt acccttcgct cttcagatga aggagaagtt tcttgggtgc
    62341 aaaaagacca gattccaaac ttggatctgg cctatgatat gctacctttg atggagatga
    62401 tggaagcatc ggacaaatct gaatttttct accctcgccg tacagaagac gattgggaaa
    62461 agaaaatttt ctaatccttt actaaataac ctagctgatc caaggcctcc tcgatatagt
    62521 ggaggtcttg ttgtgtttcg gcttcgacta ggtggtaatg gacaccatct gtcaattcag
    62581 ataaaggttt aaaatcagaa tgctcgactt gttctagaaa atgttgaacg tctcggcggc
    62641 aagacagttt aagcaaggtt tcaatttctc cataaacggg atggtcaatc aaagtattct
    62701 ggacatgccc accattatcg acaatagcaa ggagttcctg accgatttct tcaacttcat
    62761 gtttcacttt gaaaagtttg tgaacataag gattggtatc aatttgctta tagatgtagc
    62821 cacgattggt ggataggata ggagcgccat cggctctcaa aattgcaatg tcctgcacaa
    62881 tgacctgacg tgtgacatga aaatgttccg ccaaactttg gccattaagg gctttaggag
    62941 cttctttcaa gagttggagc agggcttgtt tgcgatcttt tgtcatagct tttcctttta
    63001 acggcgtttt cgaagcactt tatagacagc tagtgctaat gtatagtcta ccatactatg
    63061 gataattgtg ccaaatccaa ctagtacaaa tagaacatag aacatgtttt ctacattggt
    63121 acccgaagtt gcgtaaaaaa ggacacaggc taatacttca gcaagggcat gaacaacagc
    63181 caaaacaaaa ttgaaaaccc aggaagattt tggtttatct agggtatcgg ggaatttttg
    63241 taggtaaaga gctcctaaag caccaaaaga tatatgggaa aaagcccgaa aaactataac
    63301 catgggatag ccagccatca aaaatccaaa actagaggct aggatgacaa aaactgccat
    63361 caagggcgac aagaacatgg ctataaaaat agcgatgtgg ctccccaaag tataggaagc
    63421 aggtggaatg acaatcttga aaggcataac aattggaatc aaaatcgcaa tagccgttaa
    63481 aagggctgtc attgtcataa attgtgtctt tttccgtgta ttcacaagaa tctccttttt
    63541 aactgcatat acactagtat ggtacaataa accagacaat aaagcaagaa tttacttggg
    63601 tttatagatc attttttagt taaaagttat agtagattga aactagaata gtccacctct
    63661 acttctaaaa cattgttaga aatctatttg actgtcctga tcgatttgtc ctgttcttat
    63721 ttcgttttac tatagtaaag atttcattaa aaagaaactg tatagagcaa aatctccacc
    63781 ttcaggtttg aaagcggaga ttgtttttat tttttcaagg tttgtagtcg tggaacaatg
    63841 gctagggtta gaattgcaga aatgaccaat tcagcaattg aatttgttga gataacggtt
    63901 gccagaagaa gttggatatt tccattataa acatttccaa ataggaagaa gattcctcca
    63961 aggacaaaga tagtatttgt caaggaacca agggctccag ctaaaatcag accagtcttg
    64021 tttttcatca gtttatagac taagtaagga gttaaaccaa tcaaaatacg tgggacgatg
    64081 gcaatgatag ctgagtagat gtttccgttt ggtacgaagg gagagaagag gtagcttgtc
    64141 ggtagaatcg taatcgtgtt aaccgtcaag ctaagtaatc ccatcaaaaa tccaagtgta
    64201 atcccaactc gtggaccata aataatgctg gcaataatga caggaatatg aacaatggtc
    64261 ggtttgattg gaaatggaaa aaggttaaag ataagtgagc tcagaaagtg tatcacgagc
    64321 atggtagcaa aaaagatagc aatgggtgca atattagagc gttttttcat cgatagtttc
    64381 ctttattctt tctaaaataa ttgtgaggtc agctaaagct cctcgtccgt ggtctccaca
    64441 agctagtagg gattccttag gagcaatcag ctgatagccg taggtttcta atgttttcag
    64501 attattctga gttactggat ggtcatacat ttttgtattc atagcaggag ctattagttt
    64561 gggaatatga cttggtaggg ctagagctgt actggttacc atgttgtccg caaatccgtg
    64621 agctagtttt gcaatagtgt tagcagttgc aggtaccacg ataaataaat ctgctttttt
    64681 tccaagttcg atatgattga cctgatcagg atagggttct ttcatgacat ccaagtggac
    64741 aggattctgt gagagtacct gtagtgtcaa aggttggata aactctgtag cagcctgagt
    64801 cattaagaca gtgacttgat ggccttgttt ttttagagaa ctgactaaat ctgccgactt
    64861 ataagaggcg attgaacccg ttacagccaa gagaatgttt gccatagttt tcctttctaa
    64921 gaatgatagg cttgaatttt ttcaaggagg agttctgcaa tttcttcttt agtctggact
    64981 gtttgaagct gatttttctc aacaaatata gctcggtgct gacctgctga aatttgagtc
    65041 aggtcattcg cgatgattaa atctgcttga ttcttgataa gactttttcg tgcaatgtca
    65101 accagatgat cttcggtaac atcaaccagc agtttgaaac caatcagatg aatagtagga
    65161 ttccattcct tgactaggga tatgattttg ggtgtctttt taaggaacaa aacctgaacc
    65221 tcatcagttg aagaaatctt ggcctgatga ttctgcttgc ttaaaaattc ttttagattg
    65281 gagctagcct gaacttcctc aagccctgtc atataaacag gagtgtagtc agaaacagcc
    65341 attgagtgga tcaagacctg ataatcctga acacgttctt gcatttctat tagaaggtcc
    65401 ttggtattgg taatttctcg aatacttagg ttaggatgag gctctggctt cagagctcgt
    65461 tttgtcgtaa ttaaacaaac ttcatgccct gcagaaagca aagtctctgt gataattttc
    65521 cccaagtgac ctgtagaatg gttagtgata gagcggacgc tatcgatagc ttcactggta
    65581 ccgcccgatg taactaaaat tttcatagca ctattgtaca caaaaataag cggtaagtaa
    65641 aatgaaagtg ataaattttt ggtaaaaacg aagatttact atagtttcaa actataaagc
    65701 catataaaat ttaagaaagg actctaaaag ccttaaaaac agagatattt acgaacgttt
    65761 agagagtttt aggatgttaa aaatcttgtt ttgtgatata atgaattatc atataagagg
    65821 ttagaggaat tttgaatgaa aacagatatt gaaatcgcac agagtattga gttgaagcca
    65881 attgttgatg ttgtagagaa acttggtatt tcttacgacg atttggagtt gtacggaaag
    65941 tacaaggcta aactcagctt tgataaaatt cgtgcagttg agagcaatcc agttggtaaa
    66001 ttgatcttgg ttactgccat caacccaaca cctgcaggtg aaggaaagtc gacgcttacc
    66061 attggtcttg cggatgcctt gaacaagatt ggcaagaaaa ccatgattgc tatccgcgaa
    66121 ccgtctcttg gtccagtcat ggggatcaag ggtggtgctg ctggtggtgg gtatgcacaa
    66181 gttctgccaa tggaagacat caacctccac tttactggag atatgcatgc tattacaact
    66241 gccaacaatg ccctttctgc cttgattgac aaccacttgc accaagggaa tgagctggga
    66301 attgatcaac gtcgtatcct ctggaaacgc gttgtggact tgaacgaccg tgcgctccgc
    66361 catgtgactg ttggtcttgg tggtcctcta aacggtattc cacgtgagga tggttttgat
    66421 attacagttg cttcagaaat catggcaatt ctttgcttgg caacggacat cgaggacttg
    66481 aaacgtcgtt tggcgaatat cgttattggt tatcgctatg accgtacgcc tgtttctgta
    66541 ggtgatttgc aggttgaggg tgccttggct ttgattttga aggatgctat taagccaaac
    66601 ttggttcaga caatttacgg tacacctgcc tttgtacacg gtggtccatt tgccaatatc
    66661 gctcatggct gtaactctgt tttggcgacg acaacagccc ttcacttggc tgattacact
    66721 gttactgaag ctggttttgg tgcggacctt ggtgctgaga aattccttga tatcaagaca
    66781 ccaaacttgc caacatctcc agatgcagtt gttattgtcg caacccttcg tgcccttaag
    66841 atgaatggtg gtgtggctaa agacgctctg actgaagaaa atgtagatgc agttcgtgca
    66901 ggttttgcta acttgaaacg ccacgttgaa aatatccgta agttcggtat tccagcagtt
    66961 gtagctatta acgaatttgt atctgataca gaagctgaaa ttgcagcctt aaaagaactc
    67021 tgtgcctcaa tcgatgtacc agttgaattg gctagtgtct gggctgatgg agcagaaggt
    67081 ggagtagcac ttgccgaaac agttgttaag acaattgctg aaaatccagc taactataaa
    67141 cgtttgtacg ataatgacct ttctgtccaa gaaaagattg aaaaaattgt cactgaaatc
    67201 tatcgtggta gcaaagtgaa ctttgagaag aaagctcaaa cacaaattgc tcaaatcgtt
    67261 caaaatggtt ggggcaaatt gccaatttgt atggctaaaa ctcaatacag tttctcagac
    67321 aatccaaatg cgcttggagc accagaaaac tttgaaatta ccattcgtga attggtacca
    67381 aaattaggtg caggcttcat cgttgcctta actggtgatg ttatgaccat gccaggtctt
    67441 ccaaaacgtc cagcagctct caacatggat gttgaaagcg atggaactgt actaggcttg
    67501 ttctagtgga ttgaaattga ctttaagtga gtttggaaat aatatccaag ctcatttttt
    67561 ctcagactgc aagcagttca tcaataagat ttatactctt cgaaaatctc ttcaaac
//
LOCUS       DBEJZJ010000009        58950 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000009 DBEJZJ010000000
VERSION     DBEJZJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 58950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.09"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL3R8_000709"
     CDS             <1..333
                     /locus_tag="ACL3R8_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR1313632.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL3R8_000710"
     CDS             500..1198
                     /locus_tag="ACL3R8_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1313633.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL3R8_000711"
     CDS             1195..2247
                     /locus_tag="ACL3R8_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR1313634.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3R8_000712"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3R8_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR1313635.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3238..3393
                     /locus_tag="ACL3R8_000713"
                     /pseudo
     CDS             3238..3393
                     /locus_tag="ACL3R8_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(3497..3634)
                     /locus_tag="ACL3R8_000714"
                     /pseudo
     CDS             complement(3497..3634)
                     /locus_tag="ACL3R8_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3714..3974
                     /locus_tag="ACL3R8_000715"
     CDS             3714..3974
                     /locus_tag="ACL3R8_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313636.1"
                     /translation="MTGVSNPTTDSARLVLADSKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            3928..4149
                     /locus_tag="ACL3R8_000716"
     CDS             3928..4149
                     /locus_tag="ACL3R8_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313637.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            4468..5397
                     /locus_tag="ACL3R8_000717"
     CDS             4468..5397
                     /locus_tag="ACL3R8_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313638.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5411..6334
                     /locus_tag="ACL3R8_000718"
     CDS             5411..6334
                     /locus_tag="ACL3R8_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313639.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6438..7913
                     /locus_tag="ACL3R8_000719"
     CDS             6438..7913
                     /locus_tag="ACL3R8_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313640.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKSVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8185..9171
                     /locus_tag="ACL3R8_000720"
     CDS             8185..9171
                     /locus_tag="ACL3R8_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR1313641.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9293..10144
                     /locus_tag="ACL3R8_000721"
     CDS             9293..10144
                     /locus_tag="ACL3R8_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR1313642.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDVPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLA"
     gene            complement(10225..11289)
                     /locus_tag="ACL3R8_000722"
     CDS             complement(10225..11289)
                     /locus_tag="ACL3R8_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR1313643.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEERAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11352..12263)
                     /locus_tag="ACL3R8_000723"
     CDS             complement(11352..12263)
                     /locus_tag="ACL3R8_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR1313644.1"
                     /translation="MRKWTKGFLIFGVATTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSANHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12256..12848)
                     /locus_tag="ACL3R8_000724"
                     /pseudo
     CDS             complement(12256..12848)
                     /locus_tag="ACL3R8_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
     gene            complement(12835..13161)
                     /locus_tag="ACL3R8_000725"
     CDS             complement(12835..13161)
                     /locus_tag="ACL3R8_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR1313645.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13300..14466)
                     /locus_tag="ACL3R8_000726"
     CDS             complement(13300..14466)
                     /locus_tag="ACL3R8_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR1313646.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            14524..15684
                     /locus_tag="ACL3R8_000727"
     CDS             14524..15684
                     /locus_tag="ACL3R8_000727"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR1313647.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            15723..17573
                     /locus_tag="ACL3R8_000728"
     CDS             15723..17573
                     /locus_tag="ACL3R8_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR1313648.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(17831..18463)
                     /locus_tag="ACL3R8_000729"
     CDS             complement(17831..18463)
                     /locus_tag="ACL3R8_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1313649.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18485..19357)
                     /gene="sdaAA"
                     /locus_tag="ACL3R8_000730"
     CDS             complement(18485..19357)
                     /gene="sdaAA"
                     /locus_tag="ACL3R8_000730"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR1313650.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19366..20037)
                     /gene="sdaAB"
                     /locus_tag="ACL3R8_000731"
     CDS             complement(19366..20037)
                     /gene="sdaAB"
                     /locus_tag="ACL3R8_000731"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR1313651.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDDAIEEIRKIPHLHN
                     VNFFK"
     gene            20279..20866
                     /locus_tag="ACL3R8_000732"
     CDS             20279..20866
                     /locus_tag="ACL3R8_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR1313652.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(20918..21244)
                     /locus_tag="ACL3R8_000733"
                     /pseudo
     CDS             complement(20918..21244)
                     /locus_tag="ACL3R8_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            21997..22377
                     /locus_tag="ACL3R8_000734"
     CDS             21997..22377
                     /locus_tag="ACL3R8_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HGR1313653.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSADAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGVDWADGSLDGYIFA"
     gene            22379..22585
                     /locus_tag="ACL3R8_000735"
     CDS             22379..22585
                     /locus_tag="ACL3R8_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313654.1"
                     /translation="MKHFFAGIGEINFVSYLLYICVGIAPFFHVYIIGSEMNFVKIVL
                     SILGIIFVCILTIARIYRTFFYKE"
     gene            complement(22778..23641)
                     /locus_tag="ACL3R8_000736"
     CDS             complement(22778..23641)
                     /locus_tag="ACL3R8_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1313655.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRRIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            24107..24445
                     /locus_tag="ACL3R8_000737"
     CDS             24107..24445
                     /locus_tag="ACL3R8_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR1313656.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            24484..24918
                     /locus_tag="ACL3R8_000738"
     CDS             24484..24918
                     /locus_tag="ACL3R8_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313657.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDVYLFSILIIFSNFSVPFIREKEYELFKNKK"
     gene            25072..25284
                     /locus_tag="ACL3R8_000739"
     CDS             25072..25284
                     /locus_tag="ACL3R8_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313658.1"
                     /translation="MMIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            25700..26062
                     /locus_tag="ACL3R8_000740"
     CDS             25700..26062
                     /locus_tag="ACL3R8_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR1313659.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
     gene            26043..26288
                     /locus_tag="ACL3R8_000741"
     CDS             26043..26288
                     /locus_tag="ACL3R8_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313660.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            26445..27503
                     /locus_tag="ACL3R8_000742"
     CDS             26445..27503
                     /locus_tag="ACL3R8_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313661.1"
                     /translation="MKDDQKYLLAGFYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            27818..28795
                     /locus_tag="ACL3R8_000743"
     CDS             27818..28795
                     /locus_tag="ACL3R8_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313662.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            29172..29546
                     /locus_tag="ACL3R8_000744"
     CDS             29172..29546
                     /locus_tag="ACL3R8_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR1313663.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            29553..29735
                     /locus_tag="ACL3R8_000745"
     CDS             29553..29735
                     /locus_tag="ACL3R8_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313664.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMMIYPKLRK"
     gene            29754..30656
                     /locus_tag="ACL3R8_000746"
     CDS             29754..30656
                     /locus_tag="ACL3R8_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313665.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            30712..31065
                     /locus_tag="ACL3R8_000747"
     CDS             30712..31065
                     /locus_tag="ACL3R8_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR1313666.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            31062..31790
                     /locus_tag="ACL3R8_000748"
     CDS             31062..31790
                     /locus_tag="ACL3R8_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313667.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLESSSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            32269..32475
                     /locus_tag="ACL3R8_000749"
     CDS             32269..32475
                     /locus_tag="ACL3R8_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313668.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFFYKE"
     gene            32891..33430
                     /locus_tag="ACL3R8_000750"
     CDS             32891..33430
                     /locus_tag="ACL3R8_000750"
                     /inference="COORDINATES: protein motif:HMM:NF037419.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGR1313669.1"
                     /translation="MLFYFEKIWSLSLKLLDCILDYQERFNGKTCQVSTNYKYLEIFK
                     VNFCLTDLHHLFGLHKITRDYASQTKPAIQTGVFILEDFRNILLYNDVIERISLYEFI
                     SDIFYSKITSCCIVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFT
                     SAKKYAKVRKTDVKEMKWL"
     gene            33715..35622
                     /gene="pspA"
                     /locus_tag="ACL3R8_000751"
     CDS             33715..35622
                     /gene="pspA"
                     /locus_tag="ACL3R8_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HGR1313670.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSSPTFVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEKKAAAVKKIDEEHQAAN
                     LKSQQALVEFLAAQREGNPKKKKAAQAKLEEAEKAEKEKKKEFDKAQAVVVPEATELA
                     ETKKKADEAKVKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVVPQAKIAEL
                     ENEVQKLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAE
                     IAKLEKNVEDFKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPEKPAPAP
                     ETPAPEAPAEQPKPAPAPQPAPAPKPEKPAEQPKAEKTDDQQAEEDYARRSEEEYNRL
                     TQQQPPKAEKPAPAPKPEQPAPAPKIGWKQENGMWYFYNTDGSMATGWLQNNGSWYYL
                     NANGSMVTGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMATGWLQNNDSWY
                     YLNASGAMATGWAKVNGSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWVKVNGS
                     WYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVD
                     GYKVNANGEWV"
     gene            36023..37144
                     /gene="mnmA"
                     /locus_tag="ACL3R8_000752"
     CDS             36023..37144
                     /gene="mnmA"
                     /locus_tag="ACL3R8_000752"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR1313671.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            37285..37740
                     /locus_tag="ACL3R8_000753"
     CDS             37285..37740
                     /locus_tag="ACL3R8_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1313672.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEYAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            37750..39663
                     /gene="mnmG"
                     /locus_tag="ACL3R8_000754"
     CDS             37750..39663
                     /gene="mnmG"
                     /locus_tag="ACL3R8_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR1313673.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMINEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(39997..41676)
                     /locus_tag="ACL3R8_000755"
     CDS             complement(39997..41676)
                     /locus_tag="ACL3R8_000755"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR1313674.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAIKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(41678..41911)
                     /locus_tag="ACL3R8_000756"
     CDS             complement(41678..41911)
                     /locus_tag="ACL3R8_000756"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR1313675.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            42191..42406
                     /locus_tag="ACL3R8_000757"
                     /pseudo
     CDS             42191..42406
                     /locus_tag="ACL3R8_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(42729..42881)
                     /gene="cibB"
                     /locus_tag="ACL3R8_000758"
     CDS             complement(42729..42881)
                     /gene="cibB"
                     /locus_tag="ACL3R8_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR1313676.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(42884..43070)
                     /gene="cibA"
                     /locus_tag="ACL3R8_000759"
                     /pseudo
     CDS             complement(42884..43070)
                     /gene="cibA"
                     /locus_tag="ACL3R8_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
     gene            43247..43930
                     /gene="tsaB"
                     /locus_tag="ACL3R8_000760"
     CDS             43247..43930
                     /gene="tsaB"
                     /locus_tag="ACL3R8_000760"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR1313677.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEAESLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            43927..44364
                     /gene="rimI"
                     /locus_tag="ACL3R8_000761"
     CDS             43927..44364
                     /gene="rimI"
                     /locus_tag="ACL3R8_000761"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR1313678.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            44354..45364
                     /gene="tsaD"
                     /locus_tag="ACL3R8_000762"
     CDS             44354..45364
                     /gene="tsaD"
                     /locus_tag="ACL3R8_000762"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR1313679.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGESYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(45404..46709)
                     /locus_tag="ACL3R8_000763"
                     /pseudo
     CDS             complement(45404..46709)
                     /locus_tag="ACL3R8_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(47045..47327)
                     /locus_tag="ACL3R8_000764"
                     /pseudo
     CDS             complement(47045..47327)
                     /locus_tag="ACL3R8_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(47464..47754)
                     /locus_tag="ACL3R8_000765"
                     /pseudo
     CDS             complement(47464..47754)
                     /locus_tag="ACL3R8_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            47997..48863
                     /locus_tag="ACL3R8_000766"
     CDS             47997..48863
                     /locus_tag="ACL3R8_000766"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR1313680.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICYLKCRD
                     NFRLLGEIYPVL"
     gene            48917..49201
                     /locus_tag="ACL3R8_000767"
     CDS             48917..49201
                     /locus_tag="ACL3R8_000767"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1313681.1"
                     /translation="MCVLESMSQGTPVLASNVGGLSEIIEHRVDGFLFEKEDVEGVCA
                     CANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSHG"
     gene            49194..50147
                     /locus_tag="ACL3R8_000768"
                     /pseudo
     CDS             49194..50147
                     /locus_tag="ACL3R8_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            50157..51772
                     /locus_tag="ACL3R8_000769"
                     /pseudo
     CDS             50157..51772
                     /locus_tag="ACL3R8_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            52237..52460
                     /locus_tag="ACL3R8_000770"
                     /pseudo
     CDS             52237..52460
                     /locus_tag="ACL3R8_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816181.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52472..53222
                     /locus_tag="ACL3R8_000771"
                     /pseudo
     CDS             52472..53222
                     /locus_tag="ACL3R8_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            53235..54407
                     /locus_tag="ACL3R8_000772"
                     /pseudo
     CDS             53235..54407
                     /locus_tag="ACL3R8_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            54802..55665
                     /locus_tag="ACL3R8_000773"
     CDS             54802..55665
                     /locus_tag="ACL3R8_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR1313682.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVTCAGLTTSQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            55951..56184
                     /locus_tag="ACL3R8_000774"
     CDS             55951..56184
                     /locus_tag="ACL3R8_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313683.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            56206..56883
                     /locus_tag="ACL3R8_000775"
     CDS             56206..56883
                     /locus_tag="ACL3R8_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1313684.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWFYLGIFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            56895..57560
                     /locus_tag="ACL3R8_000776"
     CDS             56895..57560
                     /locus_tag="ACL3R8_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1313685.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTVLEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            57632..58858
                     /locus_tag="ACL3R8_000777"
     CDS             57632..58858
                     /locus_tag="ACL3R8_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1313686.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT        18366 a         9853 c        12296 g        18435 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagactagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctgg ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag actcctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatggtat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaaattg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caagatgttg taatatttta
     3061 ttgaataaga caggctttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgtttag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atcttttatg
     3241 gaatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac aggtagtata
     3301 acagaagcat cacacgtttt ccaaatctca cgtaatacca tttatggctg gttaaagcta
     3361 aaagagaaaa caggagagct aaaccaccaa gtatagtgta ttgaatctat aacagtacac
     3421 cttggctgct aaaatatttc tataaattaa tttggctttc ctgatagagt tgttcacatc
     3481 ttatttcaaa tcactataaa agctctataa tctctttata agatttgccc atcagacgaa
     3541 atagaacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt aaaagtgttt
     3601 tgatggtttg gatttcttct ttagttgatt tcatatcact gttatataat gctttttgat
     3661 tttagtctag tattagtaag cagactcaaa ccttagaaaa tcttttgaga tcattgacag
     3721 gtgtatcgaa tcctaccaca gattcagcac gtctggtttt ggcagactct aagaaagctt
     3781 ttgcagatga tagtttgata gagcaaggtt tacgtgatat cttgcaaaca gtcaaagatg
     3841 ccattgcttc cctagagtcc attaaggaaa gccagtcagc aactaaggat ggaggacaaa
     3901 cagcgggcaa agaaacagca ggagaagatg agtctgcaaa tcaaactcaa gaaattagcc
     3961 aaggaattaa gtaaacttct taaagactca aaccttgaaa cagtagataa ggatgtcctt
     4021 gaaaactctc aagaagaact tcaaaaagca gttttgttct tggcagatga aaaaggctct
     4081 gagcatactg cagcagagtt gattgataat cttaaagagg ttattgctaa gttgaaagca
     4141 aacgcctaat aacatattaa aaatctccag attaggaact atcgctgagt tccctagtct
     4201 ggagattttt cagtataccc cgttgttgga tgcttataac agagtgacgc catcactggg
     4261 ctaatagaga taaaataaac aattgattta ggacatttgt ttgatagtgg tgataaagtt
     4321 ttaaatctgc tacataattt gtggagtttt ttctataatt aggagtttaa cctaacctgc
     4381 aaataggagt atactaataa tgtaatcgtt atcaaaagtc taaaaaagaa tttttagatg
     4441 gatatcaaaa taaaaaggga ggaaattatg aaaaagtttt caaaaacatt gagagacaac
     4501 tggatctttc tcttgatggt tttgccaggg gcactctggt tgattctatt cttttacatt
     4561 ccagtatttg ggaacgtggt tgccttcaaa gactaccaca tgaccagtaa tggtttcata
     4621 gatagtatca taaatagtaa atgggtcgga ctcgataatt tcagattctt atttagttca
     4681 agagacgcct ttattatcac acgaaatact gtcctctaca atcttggctt tatctttcta
     4741 ggtttagttg tatctgtagg gattgccatt atcctcagcg agctccgttc taagagaatg
     4801 gtgaagattt ttcaaacttc tatgttgttc ccttacttct tgtcttgggt tatcatcagt
     4861 ttctttacag atgccttcct aaatattgat aaaggggtgt tcaatcatct attggaaagt
     4921 cttggtctca aagaagtcaa tttctacgct gacctgggca tctggcccta tctcctactt
     4981 ttcctaggta tttggaaagg ctttggatat agcagtgtca tgtactatgc gacgatcatg
     5041 ggaattgatc caacctacta cgaagcagcg acagtggacg gagctagcaa gtggcaacgt
     5101 attcgcaatg taaccattcc tcagttgact ccgcttgtaa ctgtattgac catccttgca
     5161 gtcggaaata tcttccgcgc agacttcggt ctcttctatc aaatcccaca caatgctggt
     5221 cagctttaca atgtaaccaa cgttttggac gtatatgtct ttaatggttt gactcagaca
     5281 gcagatatcg gtatggctgc agcagccggt ctttaccaat ccgttgttgg tttgattctg
     5341 gttatcctat caaacttgct tgcaagacga gtcgatccaa actcagcttt gttctagaaa
     5401 ggaggagaat atggcaaaaa agaaaattaa aaaagaaaaa attgataatg tcggcattca
     5461 ctccttcagt aagaaagcag atatcttctt cagtatcatt tcgggtttga ttgccctctc
     5521 ttgtatccta ccttttgtat tcgttatcat tatttcagtg acagacgaga aaagcctcct
     5581 ccaatacggc tatagcttct tcccatccca atttggctta gacggttttg agtttttggc
     5641 acagtttaag gataaaatcc tacaagccct cttcatctct gtctttgtaa ccgtagttgg
     5701 gacattgaca aatgtcttta tcacaacaac ctatgcctac gctatttcac ggacaacctt
     5761 taagtatcgc agatttttta ccatcttcgt ccttctcagt atgttgttca acgctggttt
     5821 ggtaccaggt tatatcatgg tgacccgtgt acttcagctt ggtgacactg tttgggcttt
     5881 gattgttcca atgcttctct caccattcaa tatcatcttg atgcgttctt ttttcaagaa
     5941 gaccattcca gaagccattc tcgaatcggc tcgtatcgat ggtgccagtg aggctcggat
     6001 tttcttccaa atctgtttgc cattgtcact accaggtatc gcaaccatca cgcttttgac
     6061 agctcttggt ttctggaatg actggttcaa cgcccttctt tacatcaaga gtgataactt
     6121 gtatccattg caatatttgc tcatgcaaat ccaacaaaat atggactaca ttgccaaagc
     6181 ggtcggcttg actggtcaac tgggagttgc tctaccgaaa gaaacaggtc gtatggccat
     6241 ggttgtggta gcaacccttc caatcgcgat tttgtatcca ttcttccaac gctactttgt
     6301 aaaaggtttg actatcggtg gtgtgaaaga atagtgctta ttgaaaaaga acatttctca
     6361 tttccaaact tcccttgcgt gaagttaaga tcattacatt gtttataagt ttaaaaataa
     6421 aaaaaggagt ttttatcatg aaaaattgga aaaaatatgc ttttgcatct gctagtgtag
     6481 tcgctttggc tgcaggtctt gctgcttgtg gcaacttgac aggtaacagc aaaaaagctg
     6541 ctgattcagg tgacaaatct gttatcaaaa tgtaccaaat cggtgacaaa ccagataact
     6601 tggatgaatt gttagcaaat gccaacaaaa tcatcgaaga aaaagttggt gccaaattgg
     6661 atatccaata ccttggctgg ggtgactatg gtaagaaaat gtcagttatc acatcatctg
     6721 gtgaaaacta tgatatcgcc tttgcagata actatattgt aaatgctcaa aaaggtgctt
     6781 atgctgactt gacagaattg tacaaaaaag aaggtaaaga cctttacaag gcacttgatc
     6841 cagcttatat caagggtaat actgtaaatg gtaagattta cgctgtacca gttgcagcca
     6901 acgtagcatc atctcaaaac tttgccttca acggaactct ccttgccaaa tatggtatcg
     6961 atatttcagg tgttacttct tacgaaactc ttgagccagt cttgaaacaa atcaaagaaa
     7021 aagctccaga cgtagtacca tttgctattg gtaaagtttt catcccatct gataactttg
     7081 actacccagt agcaaacggg cttccattcg ttattgacct tgaaggcgat actactaaag
     7141 ttgtaaaccg ttacgaagtg cctcgtttca aagaacactt gaagactctt cacaaattct
     7201 atgaagctgg ctacattcca aaagacgtcg caacaagtga cacttcattt gaccttcaac
     7261 aagatacttg gttcgttcgt gaagaaacag taggaccagc tgactacggt aacagcttgc
     7321 tttcacgtgt tgccaacaaa gatatccaaa tcaaaccaat tactaacttc atcaagaaaa
     7381 accaaacaac acaagttgct aactttgtca tctcaaacaa ctctaagaac aaagaaaaat
     7441 caatggaaat cttgaacctc ttgaatacga acccagaact cttgaacggt cttgtttacg
     7501 gtccagaagg caagaactgg gaaaaaattg aaggtaaaga aaaccgtgtt cgcgttcttg
     7561 atggctacaa aggaaacact cacatgggtg gatggaacac tggtaacaac tggatccttt
     7621 acatcaacga aaacgttaca gaccaacaaa tcgaaaattc taagaaagaa ttggcagaag
     7681 ctaaagaatc tccagcgctt ggatttatct tcaatactga caatgtgaaa tctgaaatct
     7741 cagctattgc taacacaatg caacaatttg atacagctat caacactggt actgtagacc
     7801 cagataaagc gattccagaa ttgatggaaa aattgaaatc tgaaggtgcc tacgaaaaag
     7861 tattgaacga aatgcaaaaa caatacgatg aattcttgaa aaacaaaaaa taatcagcta
     7921 aattgatttc gtgtattcat tcctaactcc taaaataaga atcactgctt tcctcaggtt
     7981 ggtctggggg agacagtggt ttttttggca caaggatata gatatccatg ttttctcttg
     8041 tccttatttt aaccattcag gaaatttcga gacccctcta caatttccag tcaaataaat
     8101 tgcattcgtt ttctcaagca ggtatactag tgtagataaa taaaaaattt agaaaattta
     8161 agaatagaaa agagaacaaa tcttatggca aaagatattc gtgtcttact ttactacctt
     8221 tatactccaa ttgaaaatgc agagcaattt gctgcagacc acttggcttt ctgtaaatca
     8281 atcggtctta aaggacgtat cctagtcgct gacgagggaa ttaacggaac agtttcaggt
     8341 gactatgaaa caactcaaaa atacatggac tacgttcaca gccttccagg aatggaagaa
     8401 ctctggttca agattgacga agaaagtgaa caagccttca agaagatgtt tgttcgctac
     8461 aagaaagaaa ttgtccacct tggtttggaa gacaacgact ttgacaatga catcaaccca
     8521 cttgaaacaa caggtgctta cttgtctcca aaagagttca aagaagcgct tcttgataaa
     8581 gataccgttg tccttgacac acgtaatgat tatgagtatg acctaggaca tttccgtggg
     8641 gctattcgcc cagatattcg caacttccgt gagttaccac aatgggtccg tgataacaag
     8701 gaaaaattca tggacaagcg tgtcgtggtt tactgtacag gtggcgttcg ctgtgagaaa
     8761 ttctcaggct ggatggttcg tgaaggttac aaagatgtcg gccaattgca cggaggaatc
     8821 gcaacttacg gtaaagaccc agaagttcaa ggtgagcttt gggatgggaa aatgtacgtc
     8881 tttgacgagc gtattgccgt tgatgtcaac catgtcaacc caactatcgt agggaaagac
     8941 tggtttgatg gaacaccatg tgaacgttat gtcaactgtg gaaatccctt ctgtaaccgt
     9001 cgtatcttga catcagaaga aaatgaagac aagtaccttc gtggatgctc acacgagtgc
     9061 cgtgttcacc cacgtaaccg ctatgtttca aaaaatgaat tgacacaagc tgaagtgatc
     9121 gagcgcctag ccgctatcgg tgaaagcttg gatcaagcag ctactgtata agatcaaaca
     9181 gtcctcaggg gctgtttttc tatgctttgt actcaaaaat ctaaagtttg tttttgtatc
     9241 tttcagaaaa ataaggtata ctgtatgtaa acgatttcaa aggagtccag ttatggcgaa
     9301 aacatttttt attccaaata aacagagcat tttaggagaa caagagattt tgaatgccaa
     9361 gtcgatcttg gccttgctag acggtttgga gtcacatagc tatgatgtag tctatctccg
     9421 tcagcctctt aatcgtctcg aatatatcga gtgtgcgata gtggggcaat cacaatttct
     9481 ctttaaggtc agttatgctg atggtcaaaa ggcttatcgt gtcgatgttc ctgacctact
     9541 aacaaagaca gactggcaga ttatcaagtc atttttagat gctttgcttg cttatacagg
     9601 gactgatatt gaaggactag atggttttga ttttgaagct tatttccaag caagtattca
     9661 agcctatcta gcagaccctg tagctcgttt tacgatttgc caaggaattt ttaatcctat
     9721 tttctttagt cgtgagaact tgaaaagctt tttagaggca gatggcttgg ctcagtttga
     9781 agcgcgtgtg cgtgcggttc aagagacaga tgcctacttt gcgagagttt ccttctatca
     9841 ggatggagaa ggaaaagtgc atggcgttta ccatctagct caaggagtca agacagtttt
     9901 accgagagaa ccgtttgttc ctgcagccta tattgagcaa ttggtggata aggaagtcca
     9961 gtgggagatt gacttggttc aaatcacagg agacggctct aaaccagaag actatgaatc
    10021 catagctcgc ttggactatg caaaattctt agaggtgtta cccccatctt tttaccacca
    10081 gctagacgcc aatcaaatag aaatacaacc catcctagta caagatttta aaacattagc
    10141 ataagaaaag taaagcagaa gcaggtcaat cgacttgctt ttttgacata gaaaaaatcc
    10201 tgccaagaat gacaggattg aattttaaag aaaggccaag atacgaagat aatctccaat
    10261 cagtgccact tcagctacaa agaagaggag gataataact ccgttcacaa ggacagacaa
    10321 gaataattga tagaaggagt cggtttcact tgcttgactt ggtcttgtaa tgatatggag
    10381 actggcaagc agaatgattc caatgctaat cacacacaag agggctgtaa atcgtaggct
    10441 atcaaagaaa gcaaagaaac tagcaatagc agtgaggaag attggaattg ccaagagttg
    10501 actatattgt tggagaacct tgtctagcgt ccagtccttt tcctggtgga taaatcgtct
    10561 cacaacgaaa ctacccaaga ggaatgaaaa gaagaagagt gttgtcgcta ctaggataga
    10621 gacgatagaa aaaagagtta aaggagctag ctgctcaggg aagcgactgt taatgcttgc
    10681 tatatgtcca tagtaagcat gtttgatgtg atagatacta aagaaaaagg aagatgcaga
    10741 aaacagaatg agcaagagaa aggctgtgta actgtgtgtg atacttgttt ccaacttact
    10801 tgtaggagat ttgatcgctt ccactagcca agaccaaaaa tcaagcactt gctctttcca
    10861 tttatcccta gattttggag cttggtcggg gatataagga ctttctaaag atttactgat
    10921 aagaagtggc tctttcgtgg ttgctttttg ctgaggaaga gcttcttggc tctcttcagc
    10981 tatagtgact ttttctgttt ctttagaaag gtctggctct tcttcagtag aattagatgc
    11041 cttcttttct tctattcctg ttctcgcttc actgtcttca ggagcttcaa ttttctcttc
    11101 ttgttggctt tccagttcga cttcagcttg agagacttcc tcctctactt gagtattttt
    11161 tccaattggt gtatcgagat tggctatcgt ttcttcagcc ttgtctgcaa cctcttgagc
    11221 tcgctcttca ggcttgttct tgcttgttgt ttttacaaaa tcattacttt caaaccattc
    11281 ttgtttcatg gtagaacctc ctttttagtt agataaatat gtttccatag tagcaaatgt
    11341 aagcgttttt gtcaacgtct gcttggtgtg gatattagat caatattatc atcagatctc
    11401 gcaatgagtt gatccttgac atcggttttt tcagttttgt aagggttgct taattccgta
    11461 cctcttgatt caggcttttc tcttgtgaat tggaagatag aaccatagtt gcttgagatg
    11521 tcccagttaa ttcgttggct ttctttctgg tctaggatga ttctgagata atctttggca
    11581 gtcagttcaa ccttgccatg gacttggata ttttcagcgt ggaagtgatt ctctgttgac
    11641 tctagctgac tatctgtaag aactgtatca aagatattaa cgatattggg cgttgtgagt
    11701 ttactgtttt tgatacgact tccttcaatt cggaggatat agctgtttgt attgagggtc
    11761 gcattttcaa ggctagcatt tatgatggtg gtttgtccgc gattggctga gatgttgatc
    11821 ccttttagag ttctcccttt tggtagctgg agaataactt cttcaaaacg actagagtag
    11881 ctacttgcga tatgaagaat cccaccaatt ccagaagaga gaaacggagt ttcagacagt
    11941 ttcttatcag tgagactcag agttctatcg ttttgatttg tgataagatc atggttagca
    12001 gaaagagatg gatggtaaga aatgtggatt tgatcatcga aagagtctgt gatggtgagc
    12061 gcgtgttggt ggagagtaat ttctaggttt tcgacttcct tgccaaaggt tagcttttcc
    12121 gtacggctat catagacagg ttctttggac atggaaagta ggctcttaat cccgtcagat
    12181 tggataccta caaaaagcag gataaagccg ataacggtag tcgccacacc aaagatgaga
    12241 aatccttttg tccatttacg catgctgatt acctctcttt ccttttttaa gaacaaattg
    12301 taccagacga acaatgagta gaccgaagaa gcgagttaca taggaaatgc caagtaaaac
    12361 tagcgaagaa gcaccgatag ccagtaaacc agaaccaaaa atcaagataa aggctgattt
    12421 ggcttgggcg aggacagtga aactttcaac taaaaatagg aatccgccga tgatacccag
    12481 tatggaaact gcaaagaaag ccagaatgac agtcaaagcg gctacaagaa ttgcgaacag
    12541 ggtcacgagg atggcaattc ccagaggaat gccgataggt gctgcaagga gggctaacaa
    12601 ggcgatatgt aaaatttgtc ggttattttt ttgagcgggt gcttcattga ttttttatcg
    12661 agaagattgg atagaacttc gtgggccgct tctttgggag ttcccaaact agcgatgagt
    12721 tcttcttctc cttcgactcc agcatcgtca aagagctctc tgaaatagtc catggcttcg
    12781 atacggtcag cttcaggtag tttcttgaga tagagttcta gctgagtcag gtattcagtt
    12841 cttgtcatgg cggatactcc cttctatgat gccattgatg gtgtctgtat agagtgccca
    12901 ttcatctttt agggtcaaga gctgctctat accaccgttt gtcaaggagt agtatttgcg
    12961 catgcgacct tggaactctc tagaataggt tgtcagaaag ctattgcctt ccaatttttt
    13021 gagaatggga tagagtgtgg attctttgat attagcgatc agcttaatgg tttggctaat
    13081 ctcataacca taagaatcac cctgctccag tacagccaag atgagaaatt caatcaaggc
    13141 agaggatgtt ggaaagtaca tgggaaacct ccttttctaa tgtgtaagat ttttatatat
    13201 aatttttcta cacatacatt gtacatctaa aagaaagccc tgtcaagaga aatgtgtaaa
    13261 atttttatat ataaaaaact tctagctaaa actagaagtt taaaggatct tatccgctct
    13321 gtccactgta aagagggcca cagtcatcag gatatcgatg agcaagaggg cagctacaga
    13381 tggtacccaa gagtggaaca ggtcaaaact gtaaccaaag agggttggcc caaaggctgc
    13441 taggatatag cctcctgttt gagataggcc ggacaattgg gctgtctttt caggggcgct
    13501 tgtcttgagt gaaaagttga ccatgagata agggaagagg gcactggttg cggttccgat
    13561 gaggagatgg atggcaagcc agtaaatgaa attattgatt gggaaaaaga gcatggaaat
    13621 gccgaccaca ccagctagtg aaaccagagt gagcatgagc tgacggttgc gagtagataa
    13681 actggttgtc aggcttggga tggtcattga aaaaggaatg ctaatcagag ataagataga
    13741 agtcagcaag ccagcttcgt gactggatag acctgcatgg atagacatgg taggtaacca
    13801 ggtcatgacg gtgtaaaaga tcaaggattg aaaacctgaa aagataataa ttgcccaaac
    13861 ctgtttatta cgcatgacct ttatttgact tttttgtttg gtttgtggag ctagtctatg
    13921 attatagcgg tgatttggga gccagaccaa aaaagttgct agacagagta acgtgaggag
    13981 aaggataagt cctttccaag aactggcttg tgtaatgggc acagctagat aggaagccag
    14041 agccgttgca atccccatag acgttacata taaggtggtc agaaaaccaa ttttctttgg
    14101 ttgattggct tggataagac taggaagcag gacattgatg actgcgacac ttgccccaac
    14161 catcaaggtt cctagataga gcaggggcag attgattagt cgaataagtg agccgatggt
    14221 caagaagaag aggctgtagg tgaagagatg ctccaagccg attttctgag ccagttgggt
    14281 agaaaatggt gaaaagaggg taaacataag gagaggcagg ctggtcaaga caccaagcga
    14341 actaacttct acctccagac cttgcgaaat atttcccaaa ataatgggta aaacagtaaa
    14401 aggagttcgc aaggaaacac caatcaggat aatacctgga acaaaaaaga gtgattgctt
    14461 tttcatataa tacctcttct agctgatttt aataacagct tattttaagg ctttttcact
    14521 ataatgtcaa gtaaggtttc tggctttcaa gataaaaatg ggaaagtctt gaaaattatg
    14581 atagaatggt ggaaggaaaa attcaggaga gtagtagtga ctcaaaatgt tgaaagtctt
    14641 ctcgtatcca ttgtaatcag tgcatacaat gaagaaaaat atctgcctgg tctaattgaa
    14701 gacttaaaaa atcaaaccta tcctaaagag aatattgaaa ttctatttat aaatgctatg
    14761 tccacagatg ggaccacagc tatcattcag caatttataa aggaagatac agagtttaac
    14821 tcaattagat tgtataacaa tcctaagaaa aatcaagcta gtggttttaa cctgggagtt
    14881 aaacattctg taggggacct tattttaaaa attgatgctc attcaaaagt tactgagact
    14941 tttgtaatga acaatgtggc tattattcaa caaggtgaat ttgtctgtgg ggggcctaga
    15001 ccgacgattg tcgaaggaaa aggaaaatgg gcagagacct tgcatcttgt tgaggaaaat
    15061 atgtttggca gtagcattgc caattatcga aatagttctg aggatagata tgtttcttct
    15121 atttttcatg gaatgtataa acgagaggtt ttccagaagg ttggtttagt aaatgagcaa
    15181 cttggccgaa ctgaagataa tgatattcat tatagaattc gagaatatgg atataaaatc
    15241 cgctatagcc caagtattct atcttatcag tatattcgac caacattcaa gaaaatgctg
    15301 catcaaaagt atttaaatgg tttgtggatt ggcttgacaa gtcatgttca gtttaagtgt
    15361 ttatcattat ttcactatgt tccttgttta tttgttttga gtcttgtgtt tagtctagca
    15421 ttgttaccga tcacattcgt attcataact ttactattag gtgcctattt tctacttttg
    15481 tcactactca ctttgctgac tttattaaaa cataaaaatg gatttctaat tgtgatgccc
    15541 tttcttttat tttccattca ctttgcttat ggctttggga cgattgtagg tttaattaga
    15601 ggatttaaat ggaagaagga gtacaaggga acaataattt atttggataa aataagccaa
    15661 ataaatcaaa atatgctaca ataacaatat agtaaaactc ttttaaggag gagtagattt
    15721 ctatgaataa aaaactaaca gattatgtga ttgatctggt ggaaatttta aataaacaac
    15781 aaaagcaggt tttctgggga atatttgata ttttcagtat ggtggtttcc ataattgtat
    15841 cttatatttt attttatggg ctgattaatc cagcacctgt tgactacatt atctatacga
    15901 gtttggcctt cctgttctat caattgatga ttggtttttg gggattgaac gcgagcatta
    15961 gtcgttacag caagattacg gatttcatga aaatcttttt tggtgtgact gctagcagtg
    16021 tcttgtcata tagtatctgt tatgccttct tgccactctt ctccatccgt ttcatcattc
    16081 tctttatctt gttgagtacc ttcttgattt tattgccacg gattacttgg cagttaatct
    16141 actccagacg caaaaaaggt agtggtgatg gagaacaccg tcggaccttc ttgattggtg
    16201 ccggtgatgg tggggctctc tttatggata gttaccaaca tccaaccagt gaattagaac
    16261 tggtcggtat tttggataag gattctaaga aaaagggtca aaaacttggt ggtattcctg
    16321 ttttgggctc ttatgacaat ctgcctgaat tagccaaacg ccatcaaatc gagcgtgtca
    16381 tcgttgcgat tccgtcgctg gatccgtcag aatatgagcg tatcttgcag atgtgtaata
    16441 agctgggtgt caaatgttac aagatgccta aggttgaaac tgttgttcag ggccttcacc
    16501 aagcaggtac tggcttccaa aaaattgata ttacggacct tttgggtcgt caggaaatcc
    16561 gtcttgacga atcgcgtctg ggtgcagaac tgacaggtaa gaccatctta gtcacaggag
    16621 ctggaggttc aatcggttct gaaatctgtc gtcaagttag tcgcttcaat cctgaacgca
    16681 ttgtcttgct cggtcatggg gaaaactcaa tctaccttgt ttatcatgaa ttgattcgta
    16741 agttccaagg gattgattat gtacctgtga ttgcggacat tcaagactat gatcgtttgt
    16801 tgcaagtctt tgagcagtac aaacctgcta ttgtttatca tgcggcagcc cacaagcatg
    16861 ttcctatgat ggagcgcaat ccaaaagaag ccttcaaaaa caatatccgt ggaacttaca
    16921 atgttgctaa ggctgttgat gaagctaaag tgtctaagat ggttatgatt tcgacagata
    16981 aggcagttaa tccaccaaat gttatgggag caaccaagcg cgtggcggag ttgattgtca
    17041 ctggctttaa ccaacgtagc caatcaacct actgtgcagt tcgttttggg aatgttcttg
    17101 gtagccgtgg tagtgtcatt ccagtctttg aacgtcagat tgctgaaggt gggcctgtaa
    17161 cggtgacaga cttccgcatg acccgttact ttatgaccat tccagaagct agccgtctgg
    17221 ttatccatgc tggtgcttat gccaaagatg gggaagtctt tatccttgat atgggcaaac
    17281 cagtcaagat ttatgacttg gccaagaaga tggtgcttct aagtggccac actgaaagtg
    17341 aaattccaat cgttgaagtt ggaatccgcc caggtgaaaa actctacgaa gaactcttgg
    17401 tatcaaccga acttgttgat aatcaagtta tggataagat tttcgttggt aaggttaatg
    17461 tcatgccttt agaatccatc aatcaaaaga ttggagagtt ccgcactctc agtggagatg
    17521 agttgaagca agctattatc gcctttgcta atcaaacaac ccacattgaa taaaaaagaa
    17581 aaacgcatag tatcaagtta cacaaccttg gtaatatgcg ttttattatg tagagactta
    17641 tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtatat ggttactgac
    17701 ttcgtcagtt ctatccacaa ccttaaaaca gtgtttagag cagcccgcag ctagtttcct
    17761 agtttgctct ttgattttca ttgagtatta cttcattttc ttctgaaatg gaattgttac
    17821 ccagtctatg ctattgaaaa tatgccaaaa cttctaaggg tttgtgagcg atataatcag
    17881 gttgatagtt tagtagatct gcttgctctc caaatcccca agtgacggcc aatttctgaa
    17941 tacctgtttc tcgagctccc agcatatcaa acttggtatc tccgatgatg atggcttgtt
    18001 ctggtgctag ttgatgtgtc tgtaaggctt ggtgaatgac atctgcctta tggggtgctt
    18061 cagggctaga accataaata ccatcaaaga aatgatggat ttccaagttt ttggccatgt
    18121 cttgagcagt agatgtattc tttgtcgtgg tgatgtagag tggataactg ctcgataact
    18181 cctcaagcaa gtctataatc tgaggaaaga gttgagcttc atagatgcct tttgccttat
    18241 agtaagaacg atatatctgc atggcttcag aaatttggtc tttggacagg caggtcgcaa
    18301 aactactttc gagaggtggt cccataaaac cacgaatagt tttggcatca gggctaggca
    18361 cccccagctc tttaaaggta taggtaaagg cattgtgaat cccgatagaa ctatcaacga
    18421 gggttccatc caaatcgaaa aaaatcgctg tgatagaggt catggtttct cctatttgat
    18481 aagcttattc tccgaaaatc tctttttgga ggcgacgacc agtaggggtg gtagcgagtc
    18541 caccttcagc tgtttcacga aaggcagttg gcatgcttgc tcctacttgg tacatggcat
    18601 cgatcacttc atccacaggg attttagatt cgatacctgc caaggccatg tctgctgcga
    18661 tgaaagcaaa gctagctccc atggcattac gtttgacaca gggaacttcg accaaacctg
    18721 caacagggtc acagatgagg cctagcatat ttttaatgac aaaggcaata gcttgactgg
    18781 cctgataagg tgttccacct gcagccagag tcaaggcggc agcactcata gcagaggctg
    18841 aaccaacttc agcttgacac ccaccctcag cacctgagat ggaggcattg tttgcgatga
    18901 ctagtccaaa ggcaccagca gcaaagagga aatccaattg ttgctcgtgg ctgaggtcta
    18961 atttttcaat agcagcagtg agaacggaag ggagacaacc ggcacttcct gcggtaggag
    19021 tagcgcagac caagcccatt ttagcattgt gttcattgac tgcgatagca tttcgggcag
    19081 cagagagaat cgtgtaatct gataaagttt tttcgttttt gatgtagtga tccaatttgg
    19141 cagcatctcc acctgtcagg ccactacgag atttattttc attgaggcca agttggacag
    19201 aggctttcat aacttccaga ttgcgttcca tgagaaggaa gacttcttca cgttcgcgac
    19261 cggtcaattc aaactctgtt gtaatcatga gttctgcgac atttccttga aagtccagat
    19321 ctgcttgctc gaccaattct ttgatagaat aaaacatgct tcctcctatt taaagaaatt
    19381 gacattgtgg agatgaggga tttttcgaat ttcttcgata gcatcatcac agttgcgact
    19441 gtcaacttcg ataatcataa tggctttttc accagctttt tcacgagtga cattcatctg
    19501 ggcgatattg ataccatagc gggaaagcgc ctctgtaaca agggcaatca tacctggaat
    19561 atcttgatga acgatgatga tagtcggtgt attcatattg agagagacgg caaaaccatt
    19621 gagttcggtt acctgaatat ttcctccacc gatagaaata ccagtcacgc tgatggtctt
    19681 gtgggcattt ttaacagtaa ttttagtggt gttagggtga ggggcattgc tgtctttctg
    19741 aatggtccag acaatcttga taccacgctt gtgggcaatt tccagactat ttggaatttc
    19801 aggatcatct gtatccattc ccaaaatacc tgcaacaagg gctaggtctg ttccgtgacc
    19861 acgataggtc ttggcaaatg agttaaaaag ttggaattca acttctgtcg gagtatcatc
    19921 aaaaatggaa gagacaatct tcccaatacg aacagcacca gcggtatggc tactagatgg
    19981 gccaatcata actggtccga tgatatcaaa gacagattga aaacgaagtg atttcatcag
    20041 tttcccctta taaaaattct tatctctatt atatcaaaga atgaggggct tggctttaat
    20101 tgtggatgaa aacctttcta atacctcaaa tagcataaaa atagtatctt ttatgacaaa
    20161 aaacacctta tttagggaaa taaaaaataa ttttgtaata tttctacata aaagtgtcaa
    20221 gaaacggtaa tatttaaagg gtatgataga actatagaaa gaaggagaat tttcgaatat
    20281 gaaatcaata actaaaaaga ttaaagcaac tcttgcagga gtagctgcct tgtttgcagt
    20341 atttgctcca tcatttgtat ctgctcaaga atcatcaact tacactgtta aagaaggtga
    20401 tacactttca gaaatcgctg aaactcacaa cacaacagtt gaaaaattgg cagaaaacaa
    20461 ccacattgat aacattcatt tgatttatgt tgatcaagag ttggttatcg atggccctgt
    20521 agcgcctgtt gcaacaccag cgccagctac ttatgcggca ccagccgctc aagatgaaac
    20581 tgtttcagct ccagtagcag aaactccagt agtaagtgaa acagttgttt caactgtaag
    20641 cggatctgaa gcagaagcca aagaatggat cgctcaaaaa gaatcaggtg gtagctatac
    20701 agctacaaat ggacgttata tcggacgtta ccaattaaca gattcatacc tgaacggtga
    20761 ctactcagct gaaaaccaag aacgtgtagc agatgcctac gttgcaggac gttacggttc
    20821 atggactgct gctaaaaact tctggcttaa caatggctgg tattaagaac taacgaacaa
    20881 ataatatgta aagagtcgag gaaatccctc ggctttttta tctttccttc gcttggtaat
    20941 agatctctac ttcttttttg agatgagaca gcatagaagt ttcctcggtt agctccagaa
    21001 gggagaaccc tttttggata agtttagaat cgtctgtaca aatcccaata gggacatagc
    21061 agatagccag cctatcgtag cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga
    21121 tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg ttgagcagga
    21181 ttgctattcg caagtcatat aaatgttgat agtttttata gacttctaag cgttgcaaga
    21241 ttttctcgga ttattgacaa ataaacggac attctgatag acgattgccc tagcggctta
    21301 ttgtaaactt tgcaaatttg gcttgtaatt ttttttataa aattcacttc gattacttga
    21361 cagttattat attttcactt attatataga taaaaggatg ggatgggagt ttaaaaattt
    21421 gaaagcgcta tccataataa taacgcataa ttttctcctt ttcgtgaaaa aagttaacgt
    21481 aattttaaaa tgagcttaat aagaggtact atgtaggtag aaaataaaga taggagaaaa
    21541 agtatgaata aaaaaatatt ttgtattcta gtatgtatta tatcattgat tagtctagct
    21601 ataatctttc catggggctg gtcgatataa tgtaagggag cttgagttgt tagtggagga
    21661 taaaatgtta agagtaatag tagttattca atctttagta ataatactgc ttgctgttgc
    21721 tttattatta tctcggaaaa actttgattc gttaaatgtt gttcttataa tgatgatcgt
    21781 atcacaattg ttgttattag tatatttgat aaaatcaggg aatcagtgat tagctgttat
    21841 ttgaattaag taaactgtta agcttcaagc agtaactggt tttaaatatt taaaataaga
    21901 taaaggaagg aagtctaatt taggtaacta aacaaagcct gcgatcactt gttaggaaac
    21961 catcctaacc atgcttaata aaaaaggaga aaataaatgg aactcgtatt accaaataat
    22021 tatgttgctc ttgagcaaga agagatgatg tatcttgatg ggggtggtgt tggtcgtaac
    22081 tggtggaata gtagaggtag ttttgcaaca gttctggatg tagatttggc catctatagt
    22141 ggtggtgcaa caatttattc tgctgatgcg ataaaaaaag ctatctcagc taatagaggg
    22201 gctattacga gaacattacg tagtttaata attaaacatg taggtagtgc agctggccat
    22261 ttagtcaata ctgcactaaa cgttgcacta actgttactg gattttcact aggtggagca
    22321 atcgcatatg gggttgattg ggctgacggt agcttagatg gttatatttt tgcttaaaat
    22381 gaaacatttt tttgcaggaa ttggtgaaat aaactttgta agttatttat tgtatatatg
    22441 tgtaggaata gccccttttt ttcacgtata tataataggt tctgaaatga attttgtgaa
    22501 aatagtgtta tctattttgg gaattatatt tgtttgtatt ttaactattg ctcgaattta
    22561 taggactttt ttctataaag aatagtttgg acttgaaatg tatttaaaaa caagaggttg
    22621 gtagattatc agcctctttc ttgtcgttga aaaagtgaga tatattgact tttgaaaaaa
    22681 atgtcataat tgagttggga taaacgtaaa agtcatactt tctcgttaaa tcgttcggcg
    22741 attctatgaa aaggtcgagg agctccctcg acttttttta taatttcttt ggttgataat
    22801 gggtctctac ttcttttttg agatgagaca gcatagaagt ttcctcggtc agctctagga
    22861 gtgagaaacc tttttggata agtttagcat tatctgtaca aatcccaata cggacatagc
    22921 agatagcaag cctatcgtag cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga
    22981 tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg ttgagcagga
    23041 ttgctattcg caagtcatat aaatgttgat agtttttata gacttctagg cgttgcaata
    23101 tttttccagt gatgagatgg aggtattcaa tgggaaaact gaaaagaatg gtattgagga
    23161 tttttagatc actctcatac catgtatctt gtttttcaat tcttctccaa agttttttga
    23221 caacctgttc tgcgtgatct gatagttccc ctgccccgtg ttgacggata taaatgacaa
    23281 cttcaagcat atctctgatt tcttctatag ggagatcgtg gtgggtcttg aggtagtctt
    23341 ggcatttttg aaataaattg acaagatcgc tggtcccgat aatggaacgc atattgagat
    23401 aggtttgcat aatctctgtg cgttgacttg gttgataaag ttgacagata tattcaaact
    23461 cttcaaaact catattgatt tgacggagaa gaaattccat attttcatat tttggggttg
    23521 tcttgccact ttcgattttt gataagctgg ttcttgagag aacaccccca cagacctctt
    23581 cttgggtcag cccctttgac tcacgtattt ctttatagac ctttccgaaa tcataacgca
    23641 tgattttctc ctttctgtga aaaaagttaa caaataataa aatcttgtta aaaatattgt
    23701 atcatagcag tgtaaaaagt aaaaaagaaa gtaaaaataa atttgtgaaa aaagttaacg
    23761 taattttaaa atgagcttaa taagaggtat gatgtaggta gaaaataaag ataggagaaa
    23821 aagtatgaat aaaaaaatat tttgtattct agtatgtatg atatcattga ttagtctggc
    23881 cataatcttt ccatggggct ggtcgatata atgtaaggga gcttgagttg ttaaaggagg
    23941 cttagtcctt ggacaaaaat ctgctgtact acaatgcttg gaaagatatc aagaacaaag
    24001 aatgatacga ttgaaactaa actgattcaa gaactactgg gcagtgattg aggtttgggt
    24061 gacatcaaag aaaagttaga ttaattctaa agaattgagt atttctatgt taaaaaaata
    24121 tccttgtacg atgcaacatg atcagtcaga ttgtgctgcg gcagttgttt caacagttct
    24181 tttatcttac aaaaaggaac tatcaatcat gaagattcgg gaaattattg gtacagacat
    24241 gtatggaacg actgtcagtg gtattgtttc aggtctgaat aagttgaatt ttacagtaaa
    24301 agctgttcga gtagcactgg aagatttgac tccaaaatta acatttcctg cgattcttca
    24361 agttaagaat gatttaggtc aaaatcattt tgtggtatta catagtataa aggagaaaat
    24421 aaagggaact cgtattacca aataattatg ttgctcttga gcaagaggag atgatgtatc
    24481 ttgatggggg gggcttattt aagcaagagt gcttgtcaag gaatttgcgc agctttagct
    24541 atgagtccag gaacttttat agcattgact ggagctgcag ttttaacaaa aaaactaata
    24601 aactatatta aggttggagg ccttggaggt tggcttattg gtgcagcagc aggtgtattg
    24661 gctcttatct ttttgataaa aatttgtgta gatactacga taaaggttct attaaacaga
    24721 atctttaagg caagtaaggt aatgaaaagg aggatatttt ctctttttgt actagatttg
    24781 atggtctata tatttttagg ttatgtttta gtgatacaaa aagacgtata tctgttttca
    24841 attctgataa ttttttctaa tttttcagtt ccctttatca gagaaaaaga gtatgaatta
    24901 tttaaaaata agaaatgaga tagatatggt agctttatta aaactgagaa taaagtttgg
    24961 gagatatttt tatttatttt aggtgtgttg ttaattgtaa tttcattact aagtccccca
    25021 aaaattaaat tttggaaata gagttagtga gaaggatagg ataatagtat tatgatgatt
    25081 gttttaattt cagttattgt tgcattcctg tatcataaaa ttacagagta tgtcaacaac
    25141 aggaaaattg atattgttat ttttctatca ttgctgattt ctcattttat ttggaattac
    25201 tattttttac caattgaaat attgatagca attagtggag caaatttatt attaagtttt
    25261 ttaaaaaaat tacagactaa ataatattaa tctgtgtaat acagtagctc ggtcattaga
    25321 ttctattgaa gatataaatt aaaaacgagg ttgggaaaaa actcaatttg aaaatgagat
    25381 tgagtaaatc tttctatcta tataacgtat atcatcaata tttttgaaca cctgataata
    25441 tgcatttttc ttattttaaa gattttttgc ctttcttcat ttcttgaatg aatcggagag
    25501 atgactttat ttaggtgttt gacattacta tagataggat ttagcagtac taatatgaac
    25561 tcatattata ggtgcagact taaattttgg aagcaagcta aaggatatct tatctaggta
    25621 actaagtgct ataaacaaag tcaacgatca cttgttagga aactatccta actatgctta
    25681 ataaaaaagg agaaaataaa tggaactcgt attaccaaat aattatgttg ttcttgagca
    25741 agaagagatg atgtatcttg atgggggtgg tgttggttgt aactggtgga acaaacgtga
    25801 taatattgct gcagctgcag tttctggagg gatgtcagta taccagacat atgccattaa
    25861 aaagttaatt gctaatcgtg gtatgatgag ccgagtcgtt agaagtgcta taacaagata
    25921 tattggtgga gttagtatgg caactattac taatgctctt aatattgcgg ctactgttgc
    25981 tgaagtcttc tcattaggag gagccattgc atatggttta gatatcgtag acggtaaatt
    26041 tgatggatat ttatgggcgt aaaactatag ctatgaaaca tttttttgca ggaattggtg
    26101 aaattcattt tttgttattt ttattatatc taagcatgtc taccagtcca attattggac
    26161 tagtgattgg atatactaaa ataaatctaa taaattctat tattatagct cttggtatga
    26221 tattggcatt aattttggta ttatcaagag tgtatagaaa atatttttat agagacgatg
    26281 atgactaaag tttttatcaa taatttgggc tccttgtcaa ctgtagtggg ttgaataaaa
    26341 gctaacgtct ggggaagggt ttaaagcttt gctttatcaa atattgactt acagagttgc
    26401 tctattgtat tgatgtattc ttagtaaata atatggtgtt ttgaatgaaa gatgatcaga
    26461 aatatttatt agcgggattt tattcgcttc tagttgcaat attttatttt ccattgattg
    26521 attccaaggg gatttttgta agtatattga tggcggtttt acttttatat ttaatatact
    26581 tcattggaac agtcattcat attgtgataa ttaagtttat aagaaaaaaa tcttttaagt
    26641 atttggttct atatccattt acttatgatg ggagctggag atttcaacct ataaacttac
    26701 tctactttcc agaaatggtg agagatgtca ttccgattaa tttagttcaa gaatattgcc
    26761 aaggacaacc ttacggactg ttaaaaaaga tgctgaaaag aattcgattg tcacgagaga
    26821 tatctttact cctggctacc attatcgtct atttttttac gcatagaatt ctacctcttt
    26881 cagtatttac gttcatgttt tcttacatat tgctatttgc acaatcttat ttgggtggta
    26941 ataccgtttg gattggaaat agaagattaa taatagatga tgaatttgaa aaaatcttgc
    27001 tttcaaaaag ttatgtaaaa gaaatatcat ctgcacgata ctcggaatac ttgacatgtg
    27061 aatacaaaaa ccttacacca atcatattgt tagctatttt tgaaaatttg cttgactcct
    27121 acttgcttca gaatcagagt aaggttgact tagatatttt ttataaagtt ttacctttgc
    27181 tttataaaga aaaatatact atgggattca attactttgt aagtttaaat tatttactat
    27241 ataaggttgg atttttggga atcatttacg ataatgaagc attaagagat ttgtcaaaac
    27301 aatatttaaa caaaaatatt tcggaattac aagatggttc tttcgagggc ggtatacaag
    27361 atgctgttgc ctctaaacaa atagtagtta taaatgaatt tatagcttgt ttaaattcca
    27421 gatgcgtgcc atcccaatat gatagatttt tttataaaga tagaccttat attttttcca
    27481 gaaagagtcc tattaagggg tgaaaatttg ttacatttgg attaacaagt gtcctaggga
    27541 ttagaaataa ctctagtata gctagatatt tttgagtaac tagaaatatc attaggctac
    27601 ccatatgatt gccagaaaag atggctgatg aatcttattt atactgttgc agtaggcatt
    27661 gtctaggata aataagctat cttgatgggg gagattggaa taattttagt agaaacatta
    27721 aaggattatg gacaagtagc gcaggattag gtgatgcaat gtgctaagtt ggcttggtgt
    27781 tagcagtagt attatttaac aatggaaagt agactaaatg aaaaataaac gttatttttt
    27841 tgacacaatt ttaataattt tactgcttat aagcacgata ttttgtgtca gcccagtatt
    27901 tataaaattg gacatcttag gaactccctc tcatgccatc ttaacctttg tattggcgat
    27961 accgttattc tatattttgt ctcaatgctt acatactttg ctattactag tttcctcaat
    28021 cttttgtaaa ttaagaccaa tttattttta ttttatattt gtgatcatta taggagctag
    28081 gaaatactat cgaattctct ttcaccaact aatgggattt agtccaggaa tagcagtgtt
    28141 ttataaggag agtcaaacaa ctaagaatct gtttaaattt tactacttct tgtactttac
    28201 aacactaatt tcatactatt ttttctttac ttttgtgtat gacaaaccgt tgcttttgcc
    28261 tcttattcca ttttctatta tcatagcatt agtacaaaaa ctttatagaa ttgagaatca
    28321 acaattattt ctgttaaaat caaaggtact aacaatactg gaatctaaga gggattgtga
    28381 gtttaatctt caggattatc atgaaatttg gaaattgcaa tcaaaatctg agttgccatg
    28441 cgtggcttta tcttatatca gtttgatcaa gccatatctt tcagagagcg tgcgtgaaca
    28501 aattgattta ttagaagtta agcgatttaa aaaaataaat catccaatat cactttatgg
    28561 tatgttggat gttataaaat taaatctata tttacggcat tataatgaaa aaaataaata
    28621 tgaatcaatg ttaaataaaa ttttagaggt aagaccagac tttgttttaa tcgagcagaa
    28681 tattgatgat agtttaaata gctcgcaacc attatcttta tctttagcca tttcagaaat
    28741 ccaacttttg cttgaagtgt atatggggat caaacatgtt tcaattagga gataaaacca
    28801 gaataatatt tgccattata ggggcaagtt gcatattagt cagtatgtat cttattccac
    28861 ttattaaaac tgagaataaa ttttgggaaa tacttttatt tatattaggt gtattgctaa
    28921 ttggaattgc gttattaagt caaaaaaaat aaattttgaa atagtattag tgagttcgca
    28981 atcatttatt gctagtggtt tagaactgtt aagtttcaaa caataattga ttttaaacct
    29041 taggtaacct ataaaaacaa ataaggtaga gaaaggatat cttatctagg tagctaagtg
    29101 ataaaaacac agtcgtctat cacttgttag gaaactatcc taactatgct taataaaaaa
    29161 ggagaaaata aatggaactc gtattaccaa ataattatgt tgttcttgag caagaagaga
    29221 tgatgtatct tgatggggga ttttctattc cgagatggcc tgttgcaaca gccattaata
    29281 tagcttttaa tggtgtttta ggtggaggag caatcagtct agttagaaat tatattcgta
    29341 attatggttt gcggcgagtt acaagcgcaa ttgctggagc agctgcaaga tatgttgggg
    29401 tacgagttgc aaatagagtg gcaggatttg cactgtctgc tattaatgga tttgcagctt
    29461 ggatgtcaat tggcgatgct attacaacaa tctgggccaa taatgatgta aataggagag
    29521 acccaaattt aaacgccttg tggtaactag atatgggtat taaaatggaa aaaatttttg
    29581 ttattatttt ttttgtatgt ctatttatat catccataac ttttttagcc tatgattttg
    29641 ttagcgaaga aataaaaaag ttgattattt ggattaatgt cgtttttttg attttaatca
    29701 tagcaatgat gatttatcca aaattaagaa aatgataagg acactgtaaa attatgatac
    29761 gtaaactaat tgttttctta ctaatgctcc ctctttttgt cttgtggcta gagttgcatg
    29821 tcctagtgaa taacttacta ttgaatctag aatctcccct tgattttgtg attagtatga
    29881 gtcttgcttt ctgtagtttg attttatcaa aaatagtttt agacatacta tacgcattga
    29941 aagatttata caagaaagaa ggtcttatta agatttttcc ctttattttt ataagaagga
    30001 aaaaagtgaa tgtgagattc tcgccctatt tttcattcca tcgtaaaagt ttgtcgcctg
    30061 atgatttaag atctaggatt atatggagtt ttattcttga aattgctatt atcctagtat
    30121 ttattttaaa aattcctttt gcaatcatca tgcttactac aatatttttc tggactataa
    30181 tggatatcaa tcatctcgtt tttaataaga cggaatttct ttttaatcaa aacaaatggc
    30241 aaaaagaaga ttcatttgaa agtaatttgc ataagatatt gatggacaaa atacaaaaat
    30301 cagaattaag ctattctgac ttaatgtccc ttcttctcta tgatgcgatg aaccaatcca
    30361 cctttttaac ggatagtgaa ctttttgagg atattttgaa aaaaatcgaa gattctcata
    30421 acacccttct gtgtacaggt cttgtcgagt tactgctgta tgagatttct attagtaaca
    30481 ataacaactg gcaagaaaag gttgataaaa ttagaataca gctcatcaga ataaatcaat
    30541 tagatttttt ctattataca agttggttaa ggcaaaattt tgatttctgt atgaatagag
    30601 agtatcataa aatgaaatct cggaaattat tactgagtaa taaaaagata gtttaagttc
    30661 gtcctatttg taaaacaaat gaaacaattt caactaagga ggagaaaaca aatggaactt
    30721 gtattaccaa ataattatgt tgtgattgat gaagaagtaa tgatgtatct tgatggggga
    30781 gcttatttaa gcaagcgtgc ttgtcaagga atttgcgcag ctttagctat gagttcagga
    30841 acttttatag cattagctgg agctgcagtt ttaaccaaaa aactaataaa ctatattaag
    30901 gttggaggtc ttggaggctg gcttattggt gcagcagcag gtgtattggc tacagcagca
    30961 gggaaaatag cttactgtat tggatatggt gttcttaata gaggttgtga tattaacggg
    31021 aacccttatc cttgggatgg attcatatct gcaacagtaa gatgagtaat gtagataaga
    31081 ttcgaaaaat acacatcatc gtgtgttggg tgtatatatt tttatcattc agggcgatta
    31141 taaatgatac ggagtatttt ttgcttattt ttttagcttt tatctactca atagtatcac
    31201 tacctctata ttctgtgaaa aataaaatag tatctatctg tctagccata aattcgattc
    31261 tgttaatgag ttttcccatt ttaatcaata agtttttccc agaaagtttt ttgacttata
    31321 ccgtattaat aagtgttttt attacagagt tgataatttt tcatttaatt gggaaagatt
    31381 ttgatactaa attgactaac gaatataaga aaattagtca gttcagaagc aaggtgtctc
    31441 aatctccttg gataaaatat ttagagagtt ctagttttat attaactata tttccatcca
    31501 ttctttatgg tacagttgat aatcatgtac tgactcttat ctttttgata aaaatttgtg
    31561 tagatactac gataaaattt ttattcatca gattatttga cacaagtact ttaatgaaga
    31621 ggagaatatt ttttcttttc gcattggatg ttatagctta cttattttta ggatatcttt
    31681 tagtgattca aaaagcaggc tatttgtttt cggttttact tcttttttct aatttttcag
    31741 ttccatttat caaagaaaag gaattcgaat tatttaaaaa tagcaagtaa tagaaacata
    31801 ggttaaatct tagaacggct taaaatcaga tatgataaag ggaaatagtc ttatctaggt
    31861 aactaagtgc tacaaacaca gtcgaggatc acttgttagg attacatttt aatcatgctt
    31921 aataagaatg gagaattcct atggggattg tattactctg aagtttcgaa taccttagtt
    31981 ctcgtgattt tgagctattc taggtttaga atccttcaga atgtaaaatt ttaagcagtc
    32041 aaagacttag aatagcccga aaacatttat tttatagcaa ttctaggctt agaattgctc
    32101 atatatatgt atttgagctg ctcgatagtt aggacagctt tattctgaga aatctgagct
    32161 atcaatgctt cagaatagta tttcgccaat ggtttttatt gaagaggtga ttgttttatg
    32221 atagtctaaa ataaaactga tttaatggag taaatggaga atcgttacat gaaacatttt
    32281 tttgcaggaa ttggtgagat aaaacttgtt ggctacttat tgtatatatg tgtaggacta
    32341 gcccctcttt ttcatatata tgtcataggt tcggaactga gttttgtgaa aatagtgtta
    32401 tctattttgg gagttatatt tgtaagtatg ttaactattg ctcgaattta taggactttt
    32461 ttctataaag aatagtttgg acttgaactg tatctaaaaa cagaggttgg tcgattatca
    32521 gcctctttct tgtcgttgaa aagagtgaga tatattgact tttgaaaaaa agatgtcata
    32581 attgagttgg gataaaccta aaagtaatat agtagattga atctggaata gtccgttatg
    32641 actgttaaaa tatttctaga aattaatttg actttcctaa tcgatttgtt cacatcttgt
    32701 ttcaatctac tatactttct cgttaaaccg ttcggcaatt catggtgaca tggacacatg
    32761 gtagtaagca cactatgtgg cttggcagag ctaaaaactg ttcccttgca ataagcctaa
    32821 taagcacaac atagggagtt agagaagccg actctaatca accactttgg gcaatagtga
    32881 gaactgccct gtgctttttt attttgaaaa aatatggagt ttgtcgttga aattacttga
    32941 ttgtattttg gactatcaag aaagattcaa tggaaaaaca tgtcaagtat caacgaatta
    33001 taagtattta gagattttca aagtgaattt ttgcttgact gatttacatc atttatttgg
    33061 cttacacaaa atcacacgag attatgctag tcaaacaaaa cctgctattc aaactggtgt
    33121 ttttatttta gaagatttta gaaatatcct attgtacaat gatgtaatcg aaaggatatc
    33181 tttatatgag tttataagtg atattttcta ttctaaaata acaagttgtt gcatcgtagc
    33241 taaggattta tctaaaaata ctatgaaatt ggacgtcata ttttttgagg ataaaaataa
    33301 aagatccgca gttttaggtt tacgaagaga taaaagcgga gtatttaaac cagttactct
    33361 acattttaca agcgctaaga aatatgctaa agttcgtaaa acagatgtga aagaaatgaa
    33421 atggctataa agattgtccg caggcttaag cttgcgtttt ttgttgttta acgaaattaa
    33481 aaaataagct ctctcatcgg aaatgttttt ataggaatga aggaagatga tgctatgttt
    33541 aaaaagagaa tcgaaaaggg caaaagtagt gtctttatct ttttggagta gaagcttatg
    33601 atatagaaat tgtaataaaa atgtaatata aaacatttga caaatattta cggagggagt
    33661 atacttaata taagtatagt ctaaaaatga ctatcagaaa agaggtaaat ttagatgaat
    33721 aagaaaaaaa tgattttaac aagtctagcc agcgtcgcta tcttaggggc tggttttgtt
    33781 acgtcttcgc ctacttttgt aagagcagaa gaagctcccg tagctagtca gtctaaagct
    33841 gagaaagact atgatgcagc gaagaaagat gctaagaatg cgaaaaaagc agtagaagat
    33901 gctcaaaagg ctttagatga cgcaaaagct gctcagaaaa aatatgacga ggatcagaag
    33961 aaaactgaaa agaaagctgc tgcggtaaag aaaattgatg aagaacatca ggcggctaat
    34021 cttaaatctc agcaagcatt agttgaattc ttagctgctc aaagagaagg taatcctaaa
    34081 aagaaaaaag ctgcgcaagc caagttagaa gaagcagaaa aagcagaaaa ggagaagaaa
    34141 aaggaatttg ataaagcaca ggcagtggta gttcctgaag caactgagtt agctgagact
    34201 aagaaaaaag cagacgaagc taaagtaaaa gaaccagaac ttactaaaaa actagaagaa
    34261 gctaaagcaa aatcagaaga agctgagaaa aaagctactg aagccaaaca aaaagtggat
    34321 gcagaacatg ctaaagaagt cgttcctcaa gctaaaatcg ctgagttgga aaatgaagtt
    34381 cagaaactag aaaaagatct caaagagatt gatgaatctg actcagaaga ttatgttaaa
    34441 gaaggtctcc gtgctcctct tcaatctgaa ttggatgcca aacaagctaa actatcaaaa
    34501 cttgaagagt tgagtgataa gattgatgag ttagacgctg aaattgcaaa acttgaaaaa
    34561 aatgtagaag atttcaaaaa ctcaaacggt gagcaagctg aacaataccg tgctgcagct
    34621 gaagaagact tagctgctaa acaagctgaa ttagaaaaaa ctgaagctga ccttaagaaa
    34681 gcagttaatg agccagaaaa accagctcca gctccagaaa ctccagcccc agaagcacca
    34741 gctgaacaac caaaaccagc gccggctcct caaccagctc ctgcaccaaa accagagaag
    34801 ccagctgaac aaccaaaagc agaaaaaaca gatgatcaac aagctgaaga agactatgct
    34861 cgtagatcag aagaagaata taaccgcttg actcaacagc aaccgccaaa agcagaaaaa
    34921 ccagctcccg caccaaaacc agagcaacca gctcctgcac caaaaatagg ctggaaacaa
    34981 gaaaacggta tgtggtactt ctacaatact gatggttcaa tggcaacagg atggctccaa
    35041 aacaatggtt catggtacta cctcaacgct aatggttcaa tggtgacagg atggctccaa
    35101 aacaatggtt catggtacta cctcaacgct aatggttcaa tggcgacagg atggctccaa
    35161 aacaacggtt catggtatta cctcaacgct aatggtgcta tggcgacagg atggctccaa
    35221 aacaacgatt catggtatta cctaaacgct agcggcgcta tggcaacagg ttgggctaaa
    35281 gtcaacggtt catggtacta cctcaacgct aatggtgcta tggctacagg ttggctccaa
    35341 tacaacggtt catggtacta cctcaacgct aacggtgcta tggcaacagg ttgggttaaa
    35401 gtcaacggtt catggtacta cctcaacgct aacggttcaa tggcaacagg ttgggtgaaa
    35461 gatggagata cctggtacta tcttgaagca tcaggtgcta tgaaagcaag ccaatggttc
    35521 aaagtatcag ataaatggta ctatgtcaat ggtttaggtg cccttgcagt caacacaact
    35581 gtagatggct ataaagtcaa tgccaatggt gaatgggttt aagccgatta aattaaatca
    35641 tgttaagaac atttgacatt ttaattttga aacaaagata aggttcgatt gaataaattt
    35701 atgttcgtat tctttaggta cctatcttat gatttcagga aatgtcatta aaaaaacgac
    35761 tccttttctc taacttgaaa aatagattag agaaaatggg ttgttttatt tattatagtt
    35821 atttgaatga agataagaag aaggtatact cacgtcattc acatgatctg tatattgact
    35881 ataagtttta aaaaacaatt tttaagctct tccttgtctt ctctaaccaa gcgtgttata
    35941 atgaatactg ctcaagcgac cttcaatcgt gaagcacaca cgaccttcaa tcgtgaataa
    36001 acgaatagat gggagactta ccatgagtga taactctaaa acacgtgttg tcgtggggat
    36061 gagtggtggt gttgattcgt cggtgacggc tcttttgctc aaggagcagg gctacgatgt
    36121 gatcggtatc ttcatgaaga actgggatga cacagatgaa aacggcgtct gtacggcgac
    36181 cgaagattac aaggatgtgg ttgcggtggc agaccagatt ggcattccct actactctgt
    36241 caattttgaa aaagagtact gggaccgcgt ttttgagtat ttcctagcgg aataccgtgc
    36301 gggacgcacg ccaaatccgg acgttatgtg caacaaggaa atcaagttca aggccttttt
    36361 ggactatgct atgaccttgg gggcagacta tgtagcgact gggcattatg ctcgagtggt
    36421 gcgtgatgag gatggtaccg ttcacatgct tcgtggcgtg gacaatggca aggatcagac
    36481 ctatttcctc agccaacttt cgcaagaaca acttcaaaaa acgatgttcc cactaggaca
    36541 tttggaaaag cctgaagttc gaaaactagc agaagaagca ggtctttcga ctgctaagaa
    36601 gaaagactcg acagggattt gctttatcgg agaaaagaac tttaaaaact ttctcagcaa
    36661 ctacctgcca gctcagcctg gtcgtatgat gactgtggat ggtcgcgata tgggcgagca
    36721 tgcaggtctt atgtactata caatcggtca gcgtggcgga ctcggtatcg gtgggcaaca
    36781 cggtggtgac aatgcccctt ggttcgttgt cggaaaagat ctaagcaaga atattctcta
    36841 tgtaggacaa ggattctacc atgactcgct catgtcaact agcctagaag ccagtcaagt
    36901 ccactttact cgtgaaatgc cagaagagtt tacgctagaa tgtacggcta aattccgtta
    36961 ccgtcagcct gactctaagg tgaccgtcca tgtcaaagga gacaaggcag aagttatctt
    37021 tgcagaacca caacgcgcga ttacaccagg acaggcagtt gtcttttacg atggcgaaga
    37081 gtgtctaggt ggcggtttga ttgacaatgc ttaccgcgat ggacaagttt gtcagtacat
    37141 ttagattgac aaattttctc aatttgctac aataataaca gcaatagaaa tgatggtcaa
    37201 agctcatgga tgttgcaggc ttttttgtcc tgcacttctt tgtagttttg actgtttttg
    37261 tgtcgtttaa gggaaaggac aagaatgact caacaagact ttcggacaaa agtagacaat
    37321 acggtttttg gtgttcgggc tacagccttg attgtccaaa atcacaagct tctagttacc
    37381 aaagacaagg gcaagtatta cactattgga ggtgcgattc aagtcaatga aagcacggaa
    37441 tacgcggtag tccgtgaagt gaaggaagaa ctgggtgtca aagctcaagc tgggcagcta
    37501 gcttttgtgg ttgaaaatcg ttttgaacaa gacggcgttt cctatcacaa tatcgagttt
    37561 cattatctgg tggatttgct tgaagatgcc ccgttgacca tgcaggaaga tgagaaaagg
    37621 cagccctgtg agtggattga cttggataag cttgaggata tccagctagt tccagccttt
    37681 ttaaaaacgg ccctaccaga ttgggaaggc caactaagac acattcatct tgaagaatag
    37741 gagagaaaca tgacttatca ttttactgaa gaatacgata ttattgtaat tggtgcggga
    37801 cacgctgggg ttgaggcttc cttagctgct agccgtatgg gctgtaaggt cctgcttgcg
    37861 actattaaca ttgaaatgct ggctttcatg ccttgtaatc cctctatcgg tggttctgct
    37921 aaggggattg tcgtacgtga agtcgatgcc ctcggtggcg agatggccaa gaccattgac
    37981 aagacttaca tccagatgaa gatgctcaac acagggaagg ggccagctgt ccgtgctctt
    38041 cgtgcgcagg ctgacaagga actttactct aaggagatgc gcaagacagt tgaaaatcaa
    38101 gaaaatctga cccttcgtca aaccatgatt aatgagattt tggtggaaga tggcaaggtt
    38161 gtcggtgtgc gtacagccac ccatcaagaa tatgctgcta aggctgttat tgtgacgaca
    38221 gggactgctc tccgtgggga aattatcatc ggagacctca agtactcatc aggtcctaac
    38281 cacagcttgg cttctattaa cctagctgac aatctcaagg aactgggcct cgaaatcggt
    38341 cgtttcaaga caggaacccc tccacgtgtc aaggcttctt ctatcaatta cgatgtgaca
    38401 gaaatccaac caggagatga agcgcctaat cacttctcat acacttcacg tgatgaggat
    38461 tatgtcaagg accaagtgcc atgctggttg acctacacca atggtaccag tcatgagatt
    38521 atccaaaaca acctccaccg tgcgcctatg tttacaggtg tggtcaaggg agtggggcct
    38581 cgttactgtc cgtcgattga agacaagatt gtgcgctttg cggacaagga acgccaccaa
    38641 ctcttccttg agccagaagg acgtaataca gaggaagtct atgtgcaagg cctctcaacc
    38701 agtctacctg aggatgtcca gcgtgacttg gttcattcca ttaaaggttt ggaaaatgca
    38761 gagatgatgc gaacaggtta tgccattgag tacgacatgg tcttgcctca tcagttgcgt
    38821 gcgactttgg aaaccaagaa aatctcaggt ctcttcactg ctggtcagac aaatggaaca
    38881 tcaggttatg aagaagctgc tggccaaggg attatcgcgg gtatcaatgc ggctttgaaa
    38941 atccaaggca agcctgaatt gattctaaaa cgaagtgacg gttatatcgg ggtgatgatc
    39001 gacgacttgg tgaccaaggg aaccattgaa ccttaccgtc tcttgaccag tcgtgctgaa
    39061 tatcgtctca ttcttcgcca tgacaatgct gatatgcgct tgactgagat gggacgcgag
    39121 attggccttg tggacgatga acgctgggct cgttttgaaa tcaagaaaaa tcaatttgat
    39181 aatgagatga agcgcctaga cagtatcaaa ctcaagccag tcaaggaaac caatgctaag
    39241 gttgaggaaa tgggcttcaa gccgttgaca gatgcggtga cagccaagga attccttcgc
    39301 cgtccagaag tttcttacca agatgtggtg gccttcatcg gaccagctgc agaggaatta
    39361 gatgacaaga ttatcgaatt gattgaaaca gaaatcaagt acgaaggtta catctcaaaa
    39421 gccatggatc aggttgctaa gatgaagcgc atggaagaaa aacgtattcc agccaatatc
    39481 gactgggatg acattgattc tatcgcaacc gaagcccgtc agaagttcaa actcatcaat
    39541 ccagaaacca tcggccaagc cagccgtatt tcgggagtaa acccagcaga tatttctatt
    39601 ttgatggtgt atctggaagg taaaaatcgt agtatttcta aaactcttca aaaatcaaaa
    39661 tgatatgtcg taggcttctt acgaatgagt tcaaagcttg gctttgattc atctccaatc
    39721 tcccatagtt ccccgaacta tgggagctaa ctcaagttat gcattttcct agccttctgg
    39781 tctgattttc attgagtttt aatctaaaaa gaaagcatag agaaaaacag ctccgaagac
    39841 ggggctgttt tgttgatttg tactcaatga aaatcaaaga gcaaactagg aagctagccg
    39901 taggttgctc aaagcactgc tttgaggttg tggatagaac tgacgaagtc agtaacatat
    39961 atacggcaag gcgaagctga cgtggtttga agagtattat tcttcatctg gtgtgaggat
    40021 catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc gaatagcgtt
    40081 gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg cgatacgaat
    40141 ggcattgaag aggatacgct ggctttggcg aatcaagtct ccagactctc tcatgtagac
    40201 aaagcctcgg ctgaggatat ctgggccaga cagaatcatc tgcgatttga agtcaacagt
    40261 tgcgactgct agaacgacac cgtcttcaga tagatcgcga cgatctttga ggacagctgc
    40321 gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga aatgacctgc
    40381 gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga taaagatatt
    40441 gtccttctca acaccagtat ccactgctag tccagcgtgg actttttgca tgcggtattc
    40501 accgtggaca ggcatgaagt attttggctt aatcaagcgg agcatgagtt tttgctcttg
    40561 ctggccaccg tgtccagatg tatggatatt gttcacttta ccgtggataa cttcgacacc
    40621 agcttcagaa atgatgttaa tcagcttgtt gacgctagta gtgtttccag ggatgggact
    40681 agaagagaag ataacggtat cacctggttg taattgtact tgacggtggg ttccgttggc
    40741 gatacgagag agggctgcca taggctcacc ctgactacct gtacagagga taagaacttc
    40801 tcctgcagga taatctttga tttcatttgg ctcgataaag gttcccttag gagctttgat
    40861 gtagccaaga tcgattccgt tgacaatggc cttttccata gaacgaccaa agaccgcaat
    40921 cttgcgtcca gtcttaatag cagcttctgt tgcctgctgg agacggaaga tatttgaggc
    40981 aaaggatgca aagatgatac gtccttcaat accttggata atcttcataa tggactgacc
    41041 aacgactttt tcagagttgg taaaggttgg tacttccgca tttgtcgagt cagacaggag
    41101 acagagcacg ccttcttcac caagggcagc catacgatgc aagtccgcag gttctccaac
    41161 tggagtaaag tcgaacttaa agtcacccgt acagacgatt ttcccttgag gagtatgaat
    41221 gacaatcccc aaaggctctg gaatagagtg agtcgttcta aagaaagttg ccttgagatt
    41281 tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc
    41341 gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcgt agatagggac
    41401 atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat
    41461 taaaacagcc ttgacgcggt cgatattgtc cacgatgtaa gagtagtcag gaatgacata
    41521 gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga tgataatctc
    41581 gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac cgatggcaaa
    41641 aacgccgact tcttcaggtt taagagtgta ggccatatta gaactccgta atttcgaagg
    41701 cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata tactcgatat
    41761 tgtactctgg gcgattttct tcgacaagtt ggcgagcagt gatacggccc tcaagttctg
    41821 agctggcatc gatgtctagg taaagcgtgc gtgttgtttc acggcgtggg ctacgttctt
    41881 ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac aggtcagctt
    41941 attccaaact tttagcagat atttgcttga tttcattcca ttttgtgtct agattgacct
    42001 tgattcgtta caattatttc aattatacca caaaatgaaa aattagtaaa agacggaaac
    42061 gagaaagtta ggggacgatt tctttggtaa gcgtttgcaa aaataaagaa aatgtattat
    42121 gttgataacg gaagtgaaat ttattgcttg tcataattcc atatagattt taagtcaagg
    42181 aggttgccct atgtataact tatttgcttt tgctatcgga gctcgcttgg tagcttttat
    42241 tgtttttgtt gcttgcgttt atgcggggaa tcttctattt gccaaactgg aacgatgaca
    42301 aaccaagttc ttgtggaaaa ttacctttgt gactctctac tcgctttttc tcctcctcgt
    42361 gacctatgtc gtttggtttg tattttactt tggattaaat gcttagatgc cctgcttatg
    42421 ctggggtttt ttgtttgggg atgtagagat agtagattta cgacacgaaa attccacccc
    42481 atctatcaag atgaggtggt ctttgcattt ttctaacatg acatgacaat ggaattttca
    42541 aagcttatta tttttatggg agtcattgtt ctgctcaaaa atagagttga agcataaaaa
    42601 taaaacaata caaacagata aatcgaatgg taaagggata gtagtaatgt tcaaatcatt
    42661 gagaatgctg agcaaactgt aagagatgaa gacaataaaa tttatccttc taaaaatgtg
    42721 tttcttatct agcatgactt accaaacttt ttacgaaggt cttttccaat ggtataacct
    42781 gccataaata aagcgatacc aacacctaca ccaaagccac ccttgatttc ttgcaattcc
    42841 ttattagaaa tttcacgata gttgttcaaa tctttcatca tagttaatct cctcctaaaa
    42901 aataaccagc tgccaaacca gaacctataa gtgctgttcc acctgcaata gccttccaag
    42961 atactgctac tccaaagata accaagggag cgagaccgcc atcaatatct gataattcat
    43021 tttcagataa ggataaaaaa ttgattgtca agaatgtcaa aatttgtcat tgaactttcc
    43081 tccttttttc ttgttcactt ttatattcgg aaaagaaaag gaaaagtgag cattttttaa
    43141 attattttta gttaagtgag ggcactcttg tctgggggca aagaaaattc ccatgtgcca
    43201 gcttttgtag tataatagta agcagacaaa aagataggaa tgtgttatga aagtattagc
    43261 ttttgatacg tccagcaagg ctctttctct ggctatttta gaggacaagc aggttcttgc
    43321 tgagacgacg attaatatca agaaaaatca cagtattacc ctcatgccag ccattgattt
    43381 tttgatggag agtttggact ggacgcccaa ggatttggac cgaatcgtgg tggcggaagg
    43441 gccaggtagc tacacaggct tgcgaatcgc ggtagccact gccaagacct tgactcatac
    43501 tctgaacatt gagttagttg gtatgtctag cctcttggct ctggtgccat atcaacaaga
    43561 aggcttgttc gttcctttga tggatgcgcg tcgcaacaat gtttatgcag gattttatga
    43621 aaatgctaaa cctgtcatgc cagaagcgca cctatctttt gaagaggtgc tagaaaaagt
    43681 caagggtgct agtcaggtaa cctttgtcgg agaagttgcc ccctttgtgg agcagattca
    43741 agaacacttg ccaaggacta attataaaga aaccttgcct aatgcagcca atcttgctct
    43801 tttagcttgg gacaaggaag cagaatcctt gcatgatttt gtgccaaatt acctcaaacg
    43861 agtcgaggct gaggaaaact ggctcaagaa ccataccgag tctggtgagt cctacattaa
    43921 acgcctatga tagaaatcaa gcgaattcaa caacagcctg acctagctca agccatctac
    43981 gctgttatgg cagctgttta cctagtcagt ccttggactc tggagcaaat ccaagcagat
    44041 ctgtcccaag accagacttg gtatgcattg gcttatgatg gggcagaagt gattggattt
    44101 ctagctgtgc aggagaatct ttttgaagca gaagtcctgc aaatcgctgt caaaggagct
    44161 tatcagggtc agggaattgc gtcagccttg tttgctcaat tgccgacaga taaggagatt
    44221 ttcctcgaag tcagaaagtc aaatcaacga gcgcaagcat tttacaagaa agaaaaaatg
    44281 gcggtcatcg ctgagcgaaa ggcctactac catgacccag tcgaggacgc cattatcatg
    44341 aagagagaaa tagatgaagg atagatatat tttagcattt gagacatcct gtgatgagac
    44401 cagtgtcgcc gtcttgaaaa acgacgatga gctcttgtcc aatgtcattg ctagtcaaat
    44461 tgagagtcac aaacgttttg gtggcgtagt gcccgaagta gccagtcgtc accatgtcga
    44521 ggtcattaca gcctgtatcg aggaggcatt ggcagaagca gggattaccg aagaggacgt
    44581 gacagctgtt gcggttacct acggaccagg cttggtcgga gccttgctag ttggtttgtc
    44641 agctgccaag gcctttgctt gggctcacgg acttccactg attcctgtta atcacatggc
    44701 tgggcacctc atggcagctc agagtgtgga gcctttggag tttcccttgc tagccctttt
    44761 agtcagtggt gggcacacag agttggtcta tgtttctgag gctggcgatt acaagattgt
    44821 tggggaaacg cgagatgacg cggttggtga gtcctatgat aaggtcggtc gtgtcatggg
    44881 cttgacctat cctgcaggtc gtgagattga cgagctggct catcaggggc aggatattta
    44941 tgatttcccc cgtgccatga ttaaggaaga taatctggag ttctccttct caggtttgaa
    45001 atctgccttt atcaatcttc atcacaatgc cgagcaaaag ggagaaagtc tgtctacaga
    45061 ggatttgtgt gcttccttcc aagcagctgt actggatatt ctcatggcaa aaaccaagaa
    45121 ggctttggag aaatatcctg ttaaaaccct ggttgtggca ggtggtgtgg cagccaataa
    45181 aggtctcaga gaacgcctag cagccgaggt tacagatgtc aaggtcatca ttccacctct
    45241 gcgcctctgc ggagacaatg caggtatgat tgcttatgcc agtgtcagcg agtggaacaa
    45301 agaaaacttc gcaggctggg acctcaatgc caaaccaagt cttgcctttg ataccatgga
    45361 ataaagagtg gctctttgtc aagtgtagtg ggtaggcgaa aagctacaat ctggagagta
    45421 cgaaattcgt actctctttt ttgatgttca aagtcatcaa aatccgtttt ttaaaattgt
    45481 taaagttccg gaaaccaaag gttttgcgct tgataacctt aatcaaatta ttggtcgctt
    45541 caagtttagc gttggaataa ggcagcttaa gtgcgttgat aatcttatct ctatccctta
    45601 aaaaagtcca aaagaccgtt tgaaaaagcg gatgaaccgt tggcagttct tgctcaatca
    45661 atccaaagaa atggtcggca ttcttctctt gaaaatgaaa gagcaggagt tgatagagtt
    45721 cgtagtgaac ctgtaatccc tcagagtaag aaagcagctt atctcgtact tcccgatggg
    45781 ttaagtgcat tgaaacgtgg gctgatagaa tcgtttctga cagagcttga agctatcctg
    45841 gtgtagtaaa tcagtccagt ggactgattt agcccgagcc tagaaacgaa aaagcgaggg
    45901 ttccaaaagc gcttgagcgc ccgatactct aaggattttc ggtcaaattg gttcatgatt
    45961 tggattcgta ctcggttcat agctcggctc agatgttgga caatgtggaa gcggtcaaga
    46021 acaatcttcg cctttggaaa gagttgctta gcgagccgat aataagggct gtacatgtcc
    46081 atggtgatga cctcgaccag ctcccgaacc tctctctgat agcgttggaa atggtttcga
    46141 atcaccgcat aagttcgccc gtctaaaatt gcgaggatgg atttggactc aaaatcttgg
    46201 gcaatgaagc tcattttgct ctttttgaag ctatactcat cccaactcat aacttttggc
    46261 aacttggtcc aatcggtttc aaacttaaat tccctcagtt ttcggatgac ggtggaagtt
    46321 gagaccgcca atctgtgggc aatctcagtc atagactgct tttcaaggag gagctgagcg
    46381 attttttgtc tcaccatgtt ggaaatctgg caatttttct tgacaatgga tgtttgagaa
    46441 acgaccacct taaggcaatt cttgcactga aagcggcgct ttttgagatg tagtaccgtg
    46501 ggtaaaccct gacagtcgag aagcggaatt ttagaggctt tctggaaggc gtatttgatc
    46561 atcttccctt gacaatgagg acaaggagga gcgggggaat ccaactttgc ctgaacgact
    46621 agatgggttt ggtatttcag aacagacaag attttgatat ttttgtcttt caatccgagc
    46681 aaatctgtgg tattcttaag ttgttccata tgaacccttt ctaatgagtt ggttagacgc
    46741 ttttcattat aggtcatatg gggctttttt tctacaagaa acgaccctat aattcctggg
    46801 gtgggattac ccactacaga aattatagag ccaaaacatt ccaaagtctt gtctgactct
    46861 ggaatgtttt ctgttcacag ttgttttgta actgcctaat aagtaaccgc gctataacga
    46921 ggtatctacc gagattgtca attctccagt atactgttat aaaaaacaaa actggaggat
    46981 ttttttatgt ccccccatcg tcccatcgac tgttccgtag ctgcccaata acggagcata
    47041 gtcggctgaa acaagaatag gacaaaagtg cctcaagaaa agcatcgtaa tttgacaata
    47101 ttattctgag atgtttttga tgtaagccca tattttctca atgggattat actcgggtga
    47161 ataggtagga agtggtaaca gtctatgccc tgctccttac acatgttcat tctgtgaaac
    47221 cttgcattgt ccataatgat aagggatggt gtatctaaag taggtagtaa gaatttttgg
    47281 aagcaagctt cgaaaaagtc actcgtcatc gtatctttat aggtcatcgt atctttatag
    47341 gtcatcggag ccatagtata ttgaaacaaa aaagggcatt agtacttcta taacagtatc
    47401 gcaatctctg gtgtgcgttg tctcgatctt aattcaaata attatatctt cttccagaga
    47461 gactaactgc ctgctcaagg ctcgatcata ttcgagataa aaataggtct caacccctgt
    47521 ctcataaata taaataggag tcaggtagct taagtgattc aattctttaa ggaaccgatt
    47581 tactttttct gggtcttgtt cgcagtaggt acggctcttt tttagactat atcccatagc
    47641 ctttagagcg taatgaatag ttgttggagg acagttgaat tcagcagcta tttcagtcaa
    47701 ataagcatcg ggatgagttt caatatagat ctttaattta tctctatcaa ctttttcaat
    47761 taatagtgga agttttcttg aagttagtgt attgaaacgt ttttatacag tgctaaaatt
    47821 tgaagtgtag tgcagatgta tttgtaatag tattatagca attctttgga gaaggtcgag
    47881 acaagagaaa ataggtatct ttgagatata agcatgattt actataaaat tattgagtta
    47941 ttcataaaaa tttctctatc aaatatcata atgcgtcgtt taaggagatg gttacaatgc
    48001 aatatagttg tggaaaaata aatattaata tccctgatgg atatggagac attaaggata
    48061 tagtgttttc ggctcatatt atagttaggt ataataatgg acattgtgga ggcatagatc
    48121 cgcatataat tggactttgt aaaaagcaga tcagaaggat gtctctatat cctattttga
    48181 taatcgtatc tagagattca aaggttattg atgattataa aaatttagat attgcctatg
    48241 ttgattgtac tcaatgttca aataattttg aaactgcctt acacgttaaa aatattttaa
    48301 aattattaaa aatccaactt atacactgtc atggctactc aactaattat tttttatata
    48361 tgttaaaaaa acttgacaag aatggatttg gaaaggttaa gacagtgata acatgccatg
    48421 gatgggttga atataactta aaaaagaaat tcttgactta ttttgatttt tggacatatt
    48481 ctatgggaga tgcttttatt tgtgtatctg aaactatgaa aaaaagattg gagagtataa
    48541 taaaaaataa gaagatagtt gcaataaata acggaattaa tgtatcaaat agcgatttag
    48601 atgtagtagg tgttcaagac tttaaaaaag aattttgtat tccaaataac aaaaaaatca
    48661 tttgttatgt tggaaggttg gatccagaaa aaaggccgga tagattcctt gaatttgcag
    48721 aaaaattatt tttagtcaga gaagatgtga tttttattat ggctggaaat ggtagtatgt
    48781 gggctgcttt gaaagaaaaa atttgctatt tgaaatgtag agataatttc aggttacttg
    48841 gtgaaatcta tccagtacta tagtttacca aatatcggat ttattgtata ttccttctga
    48901 tacagaagga atacctatgt gtgttttaga gtcaatgtca caaggaactc cggttttagc
    48961 tagtaatgtt ggcgggttaa gtgaaattat tgaacatagg gttgatggat ttttatttga
    49021 gaaggaagat gttgagggag tgtgtgcttg tgctaatttt ttactcaatg attctgagta
    49081 tttgaaatat ataggtgaga atagtaaatc aaaaataaga aaacattttt ctgtgcaaaa
    49141 aatgtttgta gaaaccatga gagtatatga tgaattatta gagaagagta gtcatggata
    49201 ggaatataga tcaagaatta gtaagtatta taataccaac acataatagg tatgaatctc
    49261 tgattagagc tgtgaaaagt tgtttacatc aaaattataa aaatatcgaa gttataatta
    49321 ttgatgataa ttatagtaat gtaaatttaa gaaataaaat tatccatcaa tttggctata
    49381 ccaatcatag aattaagtta attttaagta atgaagattt aggtgcaact aatgccagaa
    49441 acataggtat caaaaattct agaggtaagt atatatcatt tttagacgat gatgatgaat
    49501 atatgccaga tcgaatttta aagttgatgg cttgttttaa aaagagtaga atgaagaatt
    49561 tagctttagt ttatagttat ggaataataa tttatccaaa tggtacacga gaagaggaga
    49621 agaccgattt tgttggaaat cccttgtttg ttcaaatggt tcacaatata gcaggtacgt
    49681 cattttggtt gtgtaaaaaa gaggtgctag aattaattaa tggttttgag aaaatagatt
    49741 cacatcagga cggtgttgtt ttattaaaac tacttgctca aggataccaa attgatatag
    49801 tgcgagaatt cttggtgaat tactacgctc acagtaaaga aaacggtatc actggagtga
    49861 cacaaaaaaa caattaatgc agatgaagaa tattataatt actgtaggaa atattttaat
    49921 ttattgagtt tcaacgagag aatattggtt acaaagaaat attattcttt aaacataaag
    49981 cggttactat taataggaga caaatgcaag gctttaaaag taatcaagaa ggcaagagaa
    50041 gaaaaaattt ttaacgaatt tcttttttga aatatatgtt attatatcat tttggttttt
    50101 tctattgtat atatgacaac tatgttcaat taaaatttag aaagtgagaa actattgtgt
    50161 atactattat aaaatcaaat ataaaaaaat ttagtttatt aacgatattt attgttgctg
    50221 gtcaattatt gctaatttat gcagcaacta ttaatgctct ggtgttgaat gaattaattg
    50281 cgatgaattt agagcggttt ttgaaattgt caatctacca aatgattgtc tggtgtggga
    50341 taatattcct tgactgggta gtgaaaaatt atcaggttga agtgatccaa gagtttaatc
    50401 tagagattcg aaatagagtt gccacagaca tctctaactc tacctatcaa gaatttcata
    50461 gtaaatcatc aggaacatat ctttcgtggc taaataatga tgttcagact ttaaatgatc
    50521 aggcttttaa acaacttttt ttagtaataa aaggaatttc tggtactata tttgcagttg
    50581 tgactcttaa tcactatcat tggtcattga ctgtagccac cttgttttca ttaatgatta
    50641 tgctacttgt accaaaaatc tttgcatcga aaatgcgaga agttagtcta aatttaacta
    50701 accaaaatga agctttttta aaatctagtg agactatatt gaatggattt gatgtgttag
    50761 cgtccttgaa tcttttatat gtattgccta agaaaattaa agaagcagga attttattaa
    50821 agatggttat acaaagaaag acaactgtag aaacgttagc aggcgctatt agcttctttc
    50881 tcaatatttt ttttcagata tctctcgttt ttttaacagg ctatcttgca ataaaaggaa
    50941 tagtgaaaat tggtactatt gaagcaatag gagcactaac aggtgttatt tttacagcgc
    51001 taggtgaatt aggaggtcaa ttatcctcta ttattggtac gaagcctatt tttttaaaat
    51061 tgtattcaat taatccaatt gagtcaaata aaatgaatga tatcgaacca aatgaggtga
    51121 atagagattt tccgttatat gaagcaaaaa atatttgcta taagtatgga gataaagaaa
    51181 tattaaaaaa cttaaatttt tgttttcaac gtaatgaaaa gtatttaatt ttaggtgaaa
    51241 gtggaagcgg gaaatctaca ttattaaaat tattgaatgg ctttttgaga gattatagtg
    51301 gagaattgcg attctgcggg gatgatataa aaaaacctcc tatttaaata tggtttcgaa
    51361 tgttctatat gtagatcaaa aagcttattt gtttgaaggt acgattagag ataatatttt
    51421 attggaagaa aattatactg atgaagaaat actacagtct ttagagcaag ttggtttgag
    51481 tgtaaaagat tttcctaata acattttaga ttattatgtt ggtgatgatg ggagattact
    51541 gtcaggaggg cagaaacaaa aaattacttt agctagaggg ctaattagaa ataagaaaat
    51601 agtattaatt gacgagggaa cttctgctat cgataggaga acttcgttag cgattgaacg
    51661 taagatatta gatagagagg atttgactgt cattattgtt acccatgctc cgcatccgga
    51721 acttaaacaa tattttacta agatatatca atttccaaag gattttattt aagaatatag
    51781 gggagggaaa catgagattc tattgtgaag cttatgaggt aattactgaa gagaaaaaag
    51841 tatcattttt ttatgtagat gagaaaccct taaggtatct gttatttgac tatatatttc
    51901 tactagttct agctaaaaaa aaatatccca atcttatgaa ctgcacccca aaagttagat
    51961 ttattctgtc taacttttgg ggtgcagttc attttgcata gttttggcat tcatcctaga
    52021 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    52081 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    52141 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    52201 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    52261 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    52321 tagaggatga tattgaaagg atattgaaat atttatatat atgtttattt aacgaaatat
    52381 tcattattaa gaataaggtg aatttttttg atgatgtgga atttaatcag acacttagtg
    52441 agtttttaga taaattgtag agggaatggt tatgagtaac aatactaagt atatcttttt
    52501 atctccacat ttagatgacg caattttttc ctgtggtgat tatatttcaa aattaacttc
    52561 agaaggagaa attgtacttg ttattactat attttctggt taccctttga gccaacagct
    52621 acagccctct gctaagcaat ttcataagtt gtgtaacctt gggaaatatc cgattgaaga
    52681 aaggaagaaa gaagacaggt tagcttgtga acgtctacaa tgtgatttta gacacttatc
    52741 gtactatgaa tgtctctata ggaaagatag aaatggcaat tttctatacc gtcatatcta
    52801 tagtgaatta aaaaatgagg acacattaaa gaatgatatc ataaaagagc tgttaatgca
    52861 tttagacgac aaatgtgtcg tatattgtcc gctttcactt ggtgaccatg ttgatcatgt
    52921 ttttgtgaat agtattggaa gggcgcttga atttatgcgt tataaagtaa tatattatga
    52981 ggacttccaa tatgtaagtg atagtagtat ggttggttat atgggaaaaa ctaaagaatt
    53041 aaaaatgtat caagaggaac ttgataaaaa aacattatat tgatagaata tcatcaatat
    53101 cgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    53161 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    53221 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    53281 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    53341 ataatttaaa aaaggacatt cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    53401 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    53461 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    53521 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attatttgaa
    53581 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    53641 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    53701 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    53761 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    53821 cagaagcaat tcagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    53881 aactagattt ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    53941 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    54001 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    54061 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    54121 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    54181 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    54241 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    54301 aactatttac aaaacaaagt gatctaattg ttgcaaatag atgggatagg ggccttgaag
    54361 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    54421 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    54481 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    54541 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    54601 cagtggctgt tccccaagct cgtgtactgt ccaaaaaagt tagacattct atttagaacg
    54661 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    54721 tttcaatcac caaagtgtca gaatgttttg acaaaactat aaaaacaatg atatactata
    54781 taaaaaatag gaggtggtga gatgatcgag agaatggaat tgggagaatt ttacaaagaa
    54841 ctgcgcctgg ctagaaagct caagcagtca gatgtgactt gtgctggtct aacaacctct
    54901 cagttgtcca agtttgaact agggcagtct atgttgtctg cagataagct catattagcc
    54961 atccaaggga tcaatatgaa ttttgatgag tttgggcaca agctcaacaa ctatcaagaa
    55021 tctccacata tgcgatttgg tagaaaggtt gtggatcgct ttgctcatca agatatagct
    55081 ggcttagagc aactgttgga ggaagtcgag caagaacaga tggcagagac ttatcgtcgt
    55141 ttgaatgcta ttgtaatcaa agatgccatc cactcactag ataaaagcta cccactagca
    55201 gaggaggata gcgagttttt gaccacctat ctctatgcta tcgagtcttg gacctggttt
    55261 gaactctatc tcttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    55321 tcaacctcct tactcgaaaa atccaaagaa tttaaagagt tagtacacaa tcgattgtat
    55381 atgaagcaag gactcttaaa tatcatctca gagctcatgg agcgcaaact tttttcttat
    55441 atcccaatct ttgaagccga gctggagagt atgctccgtc catacgatgt ttttgagaaa
    55501 ttattgtggc agtttttaaa gaagatgagc attttccttc aaactaaggg aagcaatcaa
    55561 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attaatagcc
    55621 ctttttgaat tgcgtttgca gcaatacaaa aagcttatcg attagttaga aatggcaaaa
    55681 taataataat ctcagcaacg attttcaata atgttaaaat ttgtttcttc atatttctcc
    55741 actcctcatt agtagtaact ttattatacc agagaagtaa tcaaattcac caaaatcgca
    55801 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    55861 tcgtgttata ctgtacttgt aaagcacttg aagcaaatcc taggtcgcag aagtggttta
    55921 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    55981 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    56041 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    56101 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    56161 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    56221 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    56281 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    56341 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    56401 tggaaagagt gtggtcgttt ccagtttcgt tggttttacc tgggtatttt ccttctttct
    56461 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    56521 ggaagtacag tcgtagaagt agccaccaat ttaacaggaa ttagctattt tgttacgcga
    56581 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    56641 atgacaagtt tatctaaagt taagagatac tatcttgatg ttcttgtttc cgctgccata
    56701 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    56761 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    56821 gctctgcatg cttcatggaa tagtttctta ctcattgtta ctttattggt atttggatat
    56881 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    56941 tagttattgc tgaccagaag ttcagtgttc tagttttacg cagcgacctt gttactgggc
    57001 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    57061 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    57121 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgtttgg aatttcgtta
    57181 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctccgactt
    57241 ttacaggggc tacagcattt ttgatgtatt ttttctatcc tgtgattgca ggtcccattt
    57301 ttgaagagat aatccatcgg ggattggtga tgacagttct ggaaaaagga aagaaatggg
    57361 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    57421 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    57481 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggcattggtc
    57541 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatc cttggggaaa
    57601 gcttcccatt tgaacttaag aaggagttgt gatgaaagta tttcttcaaa atagagattt
    57661 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    57721 cttcctgaat tatgtggcag atgcatcttt tgcccctttg gcgattttac tcatcacgat
    57781 ttcagaaacc ctgccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    57841 tcatcgtgtc ttgaaataca cagtcattag ttttgcaaaa tttttgcttt actctatagt
    57901 gtctttatca ctttcagggc agtccttttc cttgttatta gtagcattta tttgtctgat
    57961 taaccttttg tctgacacgt tgagttattt ttcaggcgcc atgctcactc cgattttcat
    58021 tagaattatt gggcaagacc atctggcaga agctattgga tttaaacagt caactgttag
    58081 tttagtgaaa acaatcagta atattctagg aggagtctta ttaggtattc tatccatcca
    58141 gtttatttcc ttgctgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    58201 aaaaactgac ctcttgaaag tagaaaaaac gattaactat caagaaggac tctctgtaaa
    58261 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    58321 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    58381 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    58441 gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg gctatctgca
    58501 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    58561 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    58621 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    58681 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    58741 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    58801 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    58861 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    58921 caacagactt ttttctcttt tctgaatgtg
//
LOCUS       DBEJZJ010000010        56053 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000010 DBEJZJ010000000
VERSION     DBEJZJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.10"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..473
                     /locus_tag="ACL3R8_000778"
     CDS             <1..473
                     /locus_tag="ACL3R8_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGR1313687.1"
                     /translation="LYYRLPTFAFIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDN
                     LFEKGKNEIKDPIGTNSVLNKKIILQKIRKLSNQPSGYWIGSLDERFLDHAIINQIDV
                     TSEQIVLMSDGFYEFYQNNQNKTFEELIKMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            531..1172
                     /locus_tag="ACL3R8_000779"
     CDS             531..1172
                     /locus_tag="ACL3R8_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR1313688.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            1185..2660
                     /gene="galT"
                     /locus_tag="ACL3R8_000780"
     CDS             1185..2660
                     /gene="galT"
                     /locus_tag="ACL3R8_000780"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR1313689.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2673..3653
                     /gene="galE"
                     /locus_tag="ACL3R8_000781"
     CDS             2673..3653
                     /gene="galE"
                     /locus_tag="ACL3R8_000781"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR1313690.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            3863..4522
                     /locus_tag="ACL3R8_000782"
     CDS             3863..4522
                     /locus_tag="ACL3R8_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR1313691.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            4547..5614
                     /locus_tag="ACL3R8_000783"
     CDS             4547..5614
                     /locus_tag="ACL3R8_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1313692.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5717..6727
                     /locus_tag="ACL3R8_000784"
     CDS             5717..6727
                     /locus_tag="ACL3R8_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313693.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIRDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6739..8430
                     /locus_tag="ACL3R8_000785"
     CDS             6739..8430
                     /locus_tag="ACL3R8_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313694.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            8433..9143
                     /locus_tag="ACL3R8_000786"
     CDS             8433..9143
                     /locus_tag="ACL3R8_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR1313695.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            9239..9607
                     /locus_tag="ACL3R8_000787"
     CDS             9239..9607
                     /locus_tag="ACL3R8_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313696.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            9715..10716
                     /locus_tag="ACL3R8_000788"
     CDS             9715..10716
                     /locus_tag="ACL3R8_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1313697.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            11857..13218
                     /gene="trpE"
                     /locus_tag="ACL3R8_000789"
     CDS             11857..13218
                     /gene="trpE"
                     /locus_tag="ACL3R8_000789"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR1313698.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPVPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSDYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            13215..13781
                     /locus_tag="ACL3R8_000790"
     CDS             13215..13781
                     /locus_tag="ACL3R8_000790"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR1313699.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            13792..14796
                     /gene="trpD"
                     /locus_tag="ACL3R8_000791"
     CDS             13792..14796
                     /gene="trpD"
                     /locus_tag="ACL3R8_000791"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR1313700.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNLGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            14793..15560
                     /gene="trpC"
                     /locus_tag="ACL3R8_000792"
     CDS             14793..15560
                     /gene="trpC"
                     /locus_tag="ACL3R8_000792"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR1313701.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            15547..16146
                     /locus_tag="ACL3R8_000793"
     CDS             15547..16146
                     /locus_tag="ACL3R8_000793"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR1313702.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKDGISGTK"
     gene            16124..17347
                     /gene="trpB"
                     /locus_tag="ACL3R8_000794"
     CDS             16124..17347
                     /gene="trpB"
                     /locus_tag="ACL3R8_000794"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR1313703.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGREIPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            17340..18116
                     /gene="trpA"
                     /locus_tag="ACL3R8_000795"
     CDS             17340..18116
                     /gene="trpA"
                     /locus_tag="ACL3R8_000795"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR1313704.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(18088..18189)
                     /locus_tag="ACL3R8_000796"
                     /pseudo
     CDS             complement(18088..18189)
                     /locus_tag="ACL3R8_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            18418..19149
                     /locus_tag="ACL3R8_000797"
     CDS             18418..19149
                     /locus_tag="ACL3R8_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313705.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            19164..20315
                     /locus_tag="ACL3R8_000798"
     CDS             19164..20315
                     /locus_tag="ACL3R8_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1313706.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(20367..21026)
                     /locus_tag="ACL3R8_000799"
     CDS             complement(20367..21026)
                     /locus_tag="ACL3R8_000799"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR1313707.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            21096..21542
                     /locus_tag="ACL3R8_000800"
     CDS             21096..21542
                     /locus_tag="ACL3R8_000800"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313708.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            complement(21770..22948)
                     /locus_tag="ACL3R8_000801"
     CDS             complement(21770..22948)
                     /locus_tag="ACL3R8_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR1313709.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            23228..24490
                     /locus_tag="ACL3R8_000802"
     CDS             23228..24490
                     /locus_tag="ACL3R8_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1313710.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            24493..25389
                     /locus_tag="ACL3R8_000803"
     CDS             24493..25389
                     /locus_tag="ACL3R8_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR1313711.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKTVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            25404..25721
                     /locus_tag="ACL3R8_000804"
     CDS             25404..25721
                     /locus_tag="ACL3R8_000804"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1313712.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            25738..26055
                     /locus_tag="ACL3R8_000805"
     CDS             25738..26055
                     /locus_tag="ACL3R8_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1313713.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            26065..27421
                     /locus_tag="ACL3R8_000806"
                     /pseudo
     CDS             26065..27421
                     /locus_tag="ACL3R8_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            27745..29220
                     /locus_tag="ACL3R8_000807"
     CDS             27745..29220
                     /locus_tag="ACL3R8_000807"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR1313714.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHTLGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            29217..30065
                     /locus_tag="ACL3R8_000808"
     CDS             29217..30065
                     /locus_tag="ACL3R8_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR1313715.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            30080..30850
                     /locus_tag="ACL3R8_000809"
     CDS             30080..30850
                     /locus_tag="ACL3R8_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR1313716.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLYQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(31128..31373)
                     /locus_tag="ACL3R8_000810"
     CDS             complement(31128..31373)
                     /locus_tag="ACL3R8_000810"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR1313717.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            31652..31891
                     /locus_tag="ACL3R8_000811"
     CDS             31652..31891
                     /locus_tag="ACL3R8_000811"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1313718.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(31984..32187)
                     /locus_tag="ACL3R8_000812"
     CDS             complement(31984..32187)
                     /locus_tag="ACL3R8_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR1313719.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(32218..32826)
                     /locus_tag="ACL3R8_000813"
     CDS             complement(32218..32826)
                     /locus_tag="ACL3R8_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR1313720.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(32865..33035)
                     /locus_tag="ACL3R8_000814"
     CDS             complement(32865..33035)
                     /locus_tag="ACL3R8_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR1313721.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(33047..33613)
                     /gene="amaP"
                     /locus_tag="ACL3R8_000815"
     CDS             complement(33047..33613)
                     /gene="amaP"
                     /locus_tag="ACL3R8_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR1313722.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(33697..33861)
                     /locus_tag="ACL3R8_000816"
     CDS             complement(33697..33861)
                     /locus_tag="ACL3R8_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR1313723.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            34304..35785
                     /gene="mgaSpn"
                     /locus_tag="ACL3R8_000817"
                     /gene_synonym="mgrA"
     CDS             34304..35785
                     /gene="mgaSpn"
                     /locus_tag="ACL3R8_000817"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR1313724.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            36146..37147
                     /locus_tag="ACL3R8_000818"
     CDS             36146..37147
                     /locus_tag="ACL3R8_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1313725.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            37297..38214
                     /locus_tag="ACL3R8_000819"
     CDS             37297..38214
                     /locus_tag="ACL3R8_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313726.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYDYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            38225..39115
                     /locus_tag="ACL3R8_000820"
     CDS             38225..39115
                     /locus_tag="ACL3R8_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313727.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            39144..40760
                     /locus_tag="ACL3R8_000821"
     CDS             39144..40760
                     /locus_tag="ACL3R8_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1313728.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKATDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTIPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSNYLAIKQKYYDQYQANKN"
     gene            40770..42089
                     /locus_tag="ACL3R8_000822"
     CDS             40770..42089
                     /locus_tag="ACL3R8_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR1313729.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(42297..42369)
                     /locus_tag="ACL3R8_000823"
     tRNA            complement(42297..42369)
                     /locus_tag="ACL3R8_000823"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42334..42336),aa:Lys,seq:ctt)
     gene            complement(42634..43905)
                     /locus_tag="ACL3R8_000824"
     CDS             complement(42634..43905)
                     /locus_tag="ACL3R8_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR1313730.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            44197..44418
                     /locus_tag="ACL3R8_000825"
     CDS             44197..44418
                     /locus_tag="ACL3R8_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313731.1"
                     /translation="MEMMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEI
                     LDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            44583..44762
                     /locus_tag="ACL3R8_000826"
     CDS             44583..44762
                     /locus_tag="ACL3R8_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313732.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            44899..45078
                     /locus_tag="ACL3R8_000827"
     CDS             44899..45078
                     /locus_tag="ACL3R8_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR1313733.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            45115..45567
                     /locus_tag="ACL3R8_000828"
     CDS             45115..45567
                     /locus_tag="ACL3R8_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR1313734.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            45858..46328
                     /locus_tag="ACL3R8_000829"
     CDS             45858..46328
                     /locus_tag="ACL3R8_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR1313735.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPKY"
     gene            46347..47435
                     /locus_tag="ACL3R8_000830"
     CDS             46347..47435
                     /locus_tag="ACL3R8_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR1313736.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            47416..47844
                     /locus_tag="ACL3R8_000831"
     CDS             47416..47844
                     /locus_tag="ACL3R8_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1313737.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            47980..48930
                     /gene="prmA"
                     /locus_tag="ACL3R8_000832"
     CDS             47980..48930
                     /gene="prmA"
                     /locus_tag="ACL3R8_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR1313738.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            48932..49675
                     /locus_tag="ACL3R8_000833"
     CDS             48932..49675
                     /locus_tag="ACL3R8_000833"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR1313739.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            49686..51482
                     /gene="pepF"
                     /locus_tag="ACL3R8_000834"
     CDS             49686..51482
                     /gene="pepF"
                     /locus_tag="ACL3R8_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR1313740.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFENFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(51542..52219)
                     /locus_tag="ACL3R8_000835"
     CDS             complement(51542..52219)
                     /locus_tag="ACL3R8_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGR1313741.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            52468..53238
                     /locus_tag="ACL3R8_000836"
     CDS             52468..53238
                     /locus_tag="ACL3R8_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313742.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            53231..53995
                     /locus_tag="ACL3R8_000837"
     CDS             53231..53995
                     /locus_tag="ACL3R8_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313743.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAILMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            54420..55211
                     /locus_tag="ACL3R8_000838"
     CDS             54420..55211
                     /locus_tag="ACL3R8_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR1313744.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWIHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            55322..55990
                     /locus_tag="ACL3R8_000839"
     CDS             55322..55990
                     /locus_tag="ACL3R8_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR1313745.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT        17570 a         8999 c        11807 g        17677 t
ORIGIN      
        1 tactatatta tcgcttacca acatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttagtaaa cgaaatggaa ataacggatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca attggtacaa
      181 atagtgtttt aaataaaaaa attattttac aaaaaatcag aaaattatct aatcaaccga
      241 gtgggtactg gataggttcg ttggatgaga gatttttaga ccatgctatt attaatcaaa
      301 tagatgttac tagtgaacaa attgttttaa tgagcgatgg cttttatgaa ttctatcaaa
      361 ataatcaaaa taaaactttt gaagagttaa ttaagatgag atttaattct tctgctattg
      421 atccaatcta tggaaagaaa gatgatgcaa gtattgtagt tattgatgtt tgatatattg
      481 tttaaaatat taattgttac tattgaactt tgttaagaag aggtacctaa atgttaaggt
      541 tatatttaga aaatgaaatt atagaattat caaataattt agagaccatt tgggtatctg
      601 tgcttgataa atatgagaag ttatttgaat atttatcaaa tgaagaacga atagaattga
      661 ttaaagaaga tttaatcata aatgagtcag ttctaaatgt tgataaaaaa ggatatgagt
      721 taatttgttt acaacatccc gtttcatatg acttaagaag aattattagt gtaataaaaa
      781 tatcaactga cattgaacgt attggggata gaattgttga aattttaaaa aatctacaga
      841 ttattcaaaa taatgaaatt ttgaagaaaa ttatttcaga aataaaaata cttcatgaag
      901 ttatcggact gcatatgaat agggctatat cttgttatag agaggaacaa tctggatgtt
      961 tagatatggt tgttatacaa aaacagaatg agatagaaga gcttagtaca aatattgaaa
     1021 agaaaataat gaattacata tttgaagatg atgggaatgt ttctgaagta attggtgctt
     1081 tagatattat tcatcacctt gataaaattg ctcatactac gcaatcaatt tataaatgga
     1141 taatgtatag aaaatatggg aacataaatt agaaagaaaa atatatgaaa acaattattg
     1201 ataattttgt tgatagagta attgaatacg gaatgtataa tgaaattgac aaaatatatg
     1261 tgaaaaatag agtactagcg ttaataggtg aggagggaac tgatcgcatt tccgatgaaa
     1321 atgacctgaa acaaataaaa gattacttag tggaaatcgc cttaaaaaac ggtaaaatta
     1381 aagatttaat cgaggaaaag gaatgtttag gagcagagtt aatgaatttc atagttcctt
     1441 tacctagtcg attaaatgat attttttgga gttcatatga tatatcacct caagaagcag
     1501 ttgaagagtt ttataagtta agtaaagata gtgattatat taaaacttct gctattgcta
     1561 agaatattga gtttcgagca tcaactaaat acggagagct agagattacg ataaatttgt
     1621 caaaacccga aaaagatcca aaaacaattg ctgctgaaaa attagtaaaa gccactaatt
     1681 atcccaaatg tttactatgt atggaaaatg aaggatatca ggggcgaata aattatccag
     1741 cacgttcgaa tcatagaatt attcgattga aacttggtga cgaagtatgg ggattccaat
     1801 attctcccta cttatacttt aatgagcatg cgatattttt aaatagtcaa catgtaccaa
     1861 tggctattac ctctaaaaca tttgaacaat tattggagat tgttgatatt ttgccaggat
     1921 attttgctgg ttcaaattct gatcttccta tctcaggagg ctccattctt agtcataacc
     1981 actaccaggg agggaaacat attttcccaa tggaaaaagc aaaatttgag agtgaatttc
     2041 gttttaaaga ctttgaggat gttaatgctg gtattgtaaa atggccaatg tcagtaatta
     2101 ggttacaaag tgaaaataaa aatcgcttgt tagatttagc tactaaaatt ctaaataagt
     2161 ggagagaata ttcagattta gaagtagaca tcattgctat gactgaagat gtcccacacc
     2221 atacggtgac tcctattgct cgtaaagtgg acgggagata tgaattagat attgttctaa
     2281 gagataatca tactactgaa cagtacccag atggtgtttt ccatcctcat caagatgtac
     2341 aacatattaa aaaggaaaat atcgggttaa tcgaagtgat gggacttgcg atattaccac
     2401 ctcgtttgaa accagagtta gaagaagttg gaaaatatct tttaggagag gataacgcaa
     2461 ttgcggatta tcatttagaa tgggccgacc aattgaaaga aaaatatcct cgcattaata
     2521 aagaagaggt taatagcgta gttcaacacg aagcaggaca agtgtttgcg agagttctgg
     2581 aagatgcagg agtttataag aatacaccgt ctgggcatga agcgtttatg agatttgtta
     2641 agtcggttgg aattaattag gaggaaacaa aaatggcaat attggtaaca ggcggagctg
     2701 gttatattgg tagccatacc gtagtagaat tactaaattt aggaaaggaa gtcatcattg
     2761 tcgacaacct ttcgaactct agcatcttgg tgctagaccg tattgaagca attacaggaa
     2821 tacgtcccgt gttttacgaa ttagatgttt gtgataaacc agcattgaga aaggtatttg
     2881 aacaagaatc gattgatgct gcaattcatt ttgcaggtta taaagctgtc ggagaatccg
     2941 tgcaaaagcc tgtgatgtac tacaaaaata atattatgag tacattggca cttgttgaag
     3001 tgatgtcaga atttaatgtt aaaaagattg tcttttcttc aagtgcgact gtatatggaa
     3061 ttaacaatca gtcacctcta attgagacta tgcaaacaag tgcgacaaat ccttatgggt
     3121 atacgaaagt gatgcttgag caaattttaa aagatgttca tgtggcagat tcagaatgga
     3181 gtattgcgtt gcttcgttat ttcaatccaa ttggtgctca tgagtctggt ttgattgggg
     3241 aagatccctc aggaattcct aacaacttga tgccctatat tgcacaagta gcggtaggta
     3301 agctgtcaga actaagtgtg ttcggaaatg attatgatac gcttgacggt actggtgtgc
     3361 gcgattatat ccatgtagta gatttagcaa taggacatat aaaagcttta gaaaaagtat
     3421 ctgaaaaaac agatgtttat atctataacc taggctcggg agaaggcact agtgtattac
     3481 aacttgtaaa tacatttgaa agtgttaata agatccctat tccttataaa atagttccaa
     3541 gacgttcagg agacgttgca acttgttatg caaatgcaga caaagcatat aaggaattaa
     3601 attggaggac aacaaaatcg attgaagaca tgtgtagaga tacatggaat tagcaatcaa
     3661 aaaatcccaa tggctataat tgatgatact gtctatatga gtgctgtatt ttggaaaaat
     3721 tacttaacct tttaatgaaa tgcatattta atgaaagata aattaaaaaa aatgtttgac
     3781 agcgcttgac aaaggaaacg gtttcattgt ataatgtaaa catagtgaca ccgatgtcaa
     3841 atataaaaaa gaaggtcttt atatgaaaaa cttaacaaaa attaagttca aagagaatgg
     3901 ggaatttaat catttccctg ggaatacagt tgtagcaaat ctttatacta aacaagattt
     3961 gatggaagtt gttgatatta ttcaatcacg ttatagagaa ttaccattta tcgataagtt
     4021 tactttaact ccaaggaatt ctattcacat gactgtaatt gaattgttgt gccatgaaaa
     4081 tcgtgaaacg gagttttgga gcagtaatct tcctctagat acacctttac aggaaataca
     4141 tgattacttt gctaaacaac ttgaaatttt tccattgttg gatgaagaaa ttcatatgcg
     4201 tataactgaa atgggaaaac aaaacatact agttgaacct gcagatgaag cttctgcaaa
     4261 gagattagaa gaaattcgta cttatgtctc agaaaaagca ggtgtttgtt tccctaatca
     4321 tgatagatat caattccata tttcaattgg gtatcttcgg attcctctaa ccgaagagga
     4381 ggaagaagag tttactaaag tcagagcaga attaactgaa attttattag agaagattcc
     4441 aactattact gtaaaccgta ttgactatac tgtatttgaa gatatgagac aatttgttcc
     4501 atatcacgaa aaatttaaat aaaataataa aaaaggagaa cttatcatga aaaaaatgaa
     4561 agtttggtct actgtacttg caacgggagt tgctcttact acacttgctg cttgctctgg
     4621 aggttcaaat tctacgactg cttcttcatc tgaagaaaaa gctgataaaa gtcaagaatt
     4681 agtaatctat tcgaactcag tctcaaatgg tcgtggtgat tggttaactg ctaaagcaaa
     4741 agaagctggt tttaatataa aaatggttga tattgctggc gctcaattag cagaccgtgt
     4801 tattgctgag aagaataatg cagttgcaga tatggtattt ggaattggtg ctgttgactc
     4861 aaataaaatt agagatcaaa aattactagt acagtacaag cctaaatggt tagataaaat
     4921 tgatcaatct ttatcagata aagataatta ttataatcct gtgattgttc aaccattagt
     4981 tttaattggg gcgcctgatg taaaagaaat gcctaaagat tggactgaat taggtagtaa
     5041 gtataaaggt aaatattcaa tttatggtct tcaaggtggt acaggacggg caattctagc
     5101 aagtatctta gttcgttacc ttgatgaaaa aggagattta ggcgtatcag aaaaaggatg
     5161 ggaagttgca aaagaatact ttgcaaatgc ctatactctt caaaaaggtg aaagctcagt
     5221 tgttaaagcg ttagataaag aaagcccaat tcaatacggt atgatctggg gttctggagc
     5281 gttaatcgga caaaaagaac aaaatgttga attcaaagtt atgactcctg agattggtgt
     5341 accatttgta actgaacaaa ctatggtttt aagcactagt aaaaaacaag cgttagctaa
     5401 agaatttatt gattggtttg gtcaatcaga aattcaagta gaatatagta aaaaatttgg
     5461 atctattcct gcaaataaag atgccctaaa agagttacct gaagatacga aaaaatttgt
     5521 tgatcaagtg aaaccacaaa atattgactg ggaagctgtt ggaaagcatt tggatgaatg
     5581 ggtagaaaaa gctgaattag aatacgtaaa ataagaaata agagttattt tttatgtcca
     5641 agtctctcta ttatttctaa atttaaggaa gaaataaaga gaggcttttg gtttagtaat
     5701 agagggagtt agtgagatga ttaaatttga taatattcaa attaaatatg gtgattttgt
     5761 tgcaattgat aatctgaatt tagatataca tgaaggggaa ttctttacat ttcttgggcc
     5821 ttcaggatgt ggtaaatcaa ctactttgag agcattggta ggttttttag atccatcatc
     5881 aggaagtatt gaagttaatg gaacagatgt cactcatttg gaacctgaaa agcgtggaat
     5941 tggtattgta tttcaatctt atgcgctatt tccaactatg actgtttttg ataatattgc
     6001 atttggttta aaagttaaga aggtagctcc agatgttatt aaagctaaag tatcagcagt
     6061 ggcagcaaaa attaagatct ctgatcaaca gttacagcgt aatgtatcag aattatctgg
     6121 gggtcaacaa caaagggtag cattggctcg tgctctggtt cttgaaccta aaattctttg
     6181 tctagatgaa ccattgtcaa accttgacgc aaaattacgt gtagatttga gaaaagagtt
     6241 gaaaagactt caaaaagagt taggtattac tactttatat gttactcatg atcaagagga
     6301 agccttgact ttatctgata gaattgcagt ctttaacaat ggatacatcg aacaggtcgg
     6361 tacaccagta gagatttatc ataattctca aactgaattt gtatgtgatt ttattagaga
     6421 tattaatgtt ttgaccgatg aaacagtcca cgaagtatta ctgaaaaata caagcgtttt
     6481 cttagaagat aaaaaaggat acattcgatt agagaaagtt cgattcaatc gtgaaactga
     6541 acaagatttc attctaaaag ggacaattat tgatgttgag ttttctggag ttacaattca
     6601 ctatacaata aaagtttctg aaagtcagat tcttaatgta acaagtattg atagtcaggc
     6661 tgctattaga tctgtcggag aaagtgtgga attatttatc acaccatcag acgttctgca
     6721 attttaagga ggtgcagtat gcgtcataaa ttaaatttaa aagattggct tattcgttta
     6781 gggttaatct ggttcttagt aacatttatt atttatccaa actttgatct agtagtgaat
     6841 gtatttgtaa aaggaggaga attttccctt gatgctgtac atcgtgttct aaaatctcag
     6901 agggcacttc agagtattat gaacagtttt aagttagcat tttcactcat tattacagtt
     6961 aatgtcgtag gtattctttg tgttctattt acagagtact ttgatattaa aggtgctaaa
     7021 attttaaaat taggttatat gacctcttta atttatggag gagtggtttt agcgactgga
     7081 tataaatttg tctatggtcc atatggattg attacaaaat ttttacaaaa tgttatccct
     7141 tctttagacc ctaactggtt tattgggtat ggtgcagtct tattcattat gacattttca
     7201 ggaactgcta atcatacatt gtttttaaca aatacaattc gaagcgttga ctatcacact
     7261 attgaggctg ctcgaaatat gggagcaaaa ccatttactg ttttccgaaa agtagtgtta
     7321 ccaaccttaa ttccaactct atttgcactt actattatgg tttttcttag tggtttatct
     7381 gcagtagcag cacccatgat tgttggtggt aaagaatttc aaactataaa tccaatgatt
     7441 attacatttg cagggatggg gaattctcgt gatttagctg ccttacttgc aattatttta
     7501 ggtattgcaa ctacaatttt gcttactatc atgaataaga tagaaaaagg tggaaattat
     7561 atttctatct ctaagactaa agcgcctctt aaaaaacaaa aaattgcgtc taagccttgg
     7621 aatatcattg ctcacattgt agcatatgga ttgttcacag ttttcatgct tccactaatt
     7681 tttatagtat tatactcatt tacagatcca gttgcaattc aaacaggtaa cttaacatta
     7741 tcaaacttta ctttagaaaa ttatcgctta ttctttagta atagtgcggc attctctcca
     7801 ttcttggtca gctttattta ttctattatt gctgcgacaa cagcaacaat tctcgcagtt
     7861 gtatttgctc gtgttgtcag aaaacataaa tctcgttttg atttcttatt tgaatatggt
     7921 gctctacttc cttggttatt accaagtacg cttttagcag taagtttatt atttactttt
     7981 aatcagccac aatttcttgt cttgaatcag attttggtag gtagtttggt aattctactt
     8041 attgcatata tagttgtaaa aatcccattt tcttatagaa tggtacgtgc tattttattt
     8101 agtgttgatg atgagatgga agatgcagca agaagtatgg gtgcttcacc tttttatact
     8161 atgatgaagg ttatcattcc atttatttta ccggttgttc tctctgttat tgctttaaac
     8221 tttaactctt tattaactga cttcgactta tctgtattcc tttaccatcc cctagctcaa
     8281 ccattaggta ttacgattcg atctgcaggt gatgaaacag caacatctaa tgcacaagct
     8341 ctggtatttg tttatacaat tgttctgatg attatttctg gaacggtatt atacttcaca
     8401 caaagaccgg ggcgtaaagt aaggaaataa tcatgacagc cactagtctt gggttatcaa
     8461 atattgaaat agttgtcagg attgttttat cagtagtcat tggtagtata attggtttag
     8521 agagagggag caaatcccag cctgcaggca tccgaactta tagtattgtt tgtctagctg
     8581 catgtttgat tatgatgacg aatgaatacg tatcttataa atttgggaca ggagatccta
     8641 cacgattagg agctcaagtt atatcaggtg tgggttttct aggcgctgga acgattctta
     8701 ttacagataa aaagaaaatt acaggtctga caactgcagc aggcatttgg gcttcggcag
     8761 gaattggatt agctattgga gtaggttttt atgagggagc tcttttagta gccatttctg
     8821 tttggggtgt gatatccatg ttccaaccac taaaaaaata tctacaaaat cgttctaaaa
     8881 tgattgaatt gtatatagtg gttaaatcta cagaagccta taatcgtgta ttggtttatt
     8941 gtgcagaaaa tggtatcaga atgaccgatt caagaacagc gtttggagat gttaattctg
     9001 acagaattga atactttgat gttccagata aaaaaatagc gtcatttatt actctggaat
     9061 tatcaggtag atttgaacat cttcgactga tggaagaaat tgctaatatt gtaggtgtta
     9121 tttatgtcga agaaattagc tgaaatttag taaacaaagg gacagatgtt tttgtccttt
     9181 tgttttttag atgttttaat catctaattt ttgagtagat ttttgctcag aggtttttat
     9241 gaaagattat aaaatcaatt ttgatttagg taaaatagaa tattttgata ataattgttt
     9301 gatacaagta tacaaattta tttcttttta tgatatttgt gaaatggtgt ttgcctttca
     9361 tttacctcct gatgagttga taacaaatgt tatctttaaa gaaaaaatta actctatgtt
     9421 aaaatgttac attgacaggc tattatatgt ttttataaat cctacacatt ttactgaaaa
     9481 agttaatcta caattttatg gcagtttttt ctcatatgaa tttatttgtc gtgaagttgg
     9541 aaacattctt aaaaataaag gtgtgaaatg caatttaaat ttttttgaag gggaagaata
     9601 tttgtaaaat taattttgtg aatttgtgga tcttaaataa tttactaaat tctcttgtta
     9661 aaaaaaatta aatattgtat agtaatatta gaatgttcgt aatggaggac tgaaatgaaa
     9721 aatataaatg ggaaaaaggt aactatttat gatattgcac gtttatcagg tttttctcca
     9781 aaaacagttt cacgagttat taatggtgga gtaaatgtta aagaagaaac ttatcaagcg
     9841 attcaaaaag ttatagagga attgtcgtat attccaaatg cgtatgcaaa aaatttaact
     9901 aaaaaagaag ctataaatat attgatttct gtaaaaaaaa tcgactcttt tcctttaatt
     9961 tggtttcata cgctgttaga taaagtgtta cggacgtgta aagaatttgg tgttaatgct
    10021 atagttgagt actttggaga ggaggataca attagtaatt caattatatc aagcacaggt
    10081 agcctagtag atggtgttat tgttttttat gaaagtgtag atgatatcag aattcagtat
    10141 ttaaagaaga accatatgcc ttttcttgtt ttcggtgaat ctcaaacgtc tggagtagtc
    10201 tatgtatcta ataataattt tcaagctact tatgatatga tgaaagctgt aactgaagaa
    10261 aaatttaaaa atatgtggtt gcttatggga ggagaatccc atgttaataa ggatcgtgaa
    10321 agaggtgtgc gttcttttct gaatgataaa aattacttta tggatttaaa agtcatttat
    10381 ggcttatcta caattgattc agtttattct tatgcaatgc agcacttgac tacccaaaat
    10441 tatccggaca ttatttttgt ttcaggagat gaaaaggttc agggcttgat tcgtgcgtgc
    10501 tatgagaaag gaattcttat tccagatgat atttctatca ttggatttga taatattcct
    10561 atttctcagt attatactcc agctttgtct acaattgctc ccaattatgt taaattggct
    10621 aaagaaatga tagaaggtgt tttagcaatt attaaagggg aaagtgtcac atctgttgaa
    10681 gtttctccta aatttgttag gagacagagt ttctagtatt gtttaattct tgaaaatcct
    10741 agtggaaaag atggagtgtt ctaaaataag ttctgtttag cctccattca gtttctattg
    10801 agttggatcc aatttctaac aagtgggaca tgttcatgtt cgatctaagg aagacatggt
    10861 cacattcgaa tgatattttc aaaaaaatcg taaaaaagtc ttgacaaaga aaaaacaaag
    10921 tattaaaata agttcaacaa atcagaaaag taactatttt tgatcttcag ggagcctgtg
    10981 gtgattgtga ataggtggtt ggaagtagtg aaagtgggct gattttgaaa atgaatttga
    11041 aacaatgaaa attcggtgcg cacaccttac agtgcagctt gttgttaaac aaggcagaga
    11101 tgtaaaggga tagtcccttt ataattgagg tggcaccgcg ttaccaacgc cctcacacgg
    11161 aagtatattc tgtgtgtggg cttttttcta tccgtcgttt ggtttatctt ttattagggc
    11221 cttaagtcgc tttgatgaac ttgagttcta tctacagctc cttgcctact actaaaagca
    11281 aacaaaaagg ctggactaat acgaaaaaag ctagtaatac tcaatgaaaa tcaaagagca
    11341 aactaggaaa ctagccgcag gctgctcaaa acactgtttt gaggttgtgg atagaactga
    11401 cgaagtcagt aaccatacct acggcaaggc gacgttgacg cggtttgaag agattttcga
    11461 agagtataaa ggtgtaccga gatgaacatc tcttcatcaa tgtctctggt cgtggaggca
    11521 aggacctagc tgcgattgca gattactaga agctaaaaaa taatagatgg aaaaattaca
    11581 gtcttttctc tcacagagag cttgtggttg ctgaaaacaa gcagagaaag ctgtaaagtt
    11641 gggttcatct gaaacgagag aagaaaacat cattctcaag ggagtgccct ttatcgcaca
    11701 gcctgttaca ggaggtatct gagacaggaa tgagagatag gagaaatcct ataattgagg
    11761 tggcaccgcg aatttcgtcc tcacgcaagt tattttgcgt ggggattttt catacagtcg
    11821 ccacgaacta gaattagaac tgaaagggaa attacaatgg aacgaatcat tcatggagat
    11881 gtcttatcac caatcttggc ttatatgcgc ttaaaggggc aacataaggt tattttagag
    11941 agtattccga gagacaagga aacggctcgt ttttctatcc tagcctataa tccagttttt
    12001 gagattaagt ttgaaaatgg agttctctat caaaatggtc aagtgattga tcgggatccc
    12061 ttggatttcc tttatgaagt gattcataag agtcagcacc actcagagct cccttttggt
    12121 ggtggagcca ttggttttgt gggttacgat atgatttcgc tttatgaaga aattggtcaa
    12181 atccctgagg atacaattgg gacgccagac atgcatttct ttgtctatga gagctatatg
    12241 gtctttgacc acaagaagga gaagatacat gtcatagagg atgcacttta tagtgagcgc
    12301 agtcaagagg ccttggaaaa atcattgaac caagtgcttg aggaattacg cattcctgtt
    12361 ccaaatgaat ttgaagactt ggatctatct ccgttagact tcaaaccgca tatcgctcca
    12421 cataagtttg agggaatggt agaaacagct cgtgacttga ttcgtaacgg agatatgttc
    12481 caatgtgtac tcagccagcg tttctcagca gaagttactg gaaatccatt tgacttctac
    12541 agaaatctcc gcgtgactaa tccttctgat tacctttatt tctatgattt tggggattat
    12601 caaatcatcg gagctagtcc agaaagtttg gtttctgtca aaaatggcat cgtgacaacc
    12661 aatccgattg cagggacgcg accaagaggg gctacggatg aagaagacaa gaccttggcg
    12721 actgacctcc tctctgatga gaaggaaaca gcagaacatc gaatgttggt agacttgggg
    12781 cgtaacgata ttggccgcat ctctgaaacg gccagtgtcc aagttactaa gtatatgaag
    12841 gtggagctct tccgctacgt catgcatttg accagtgtgg tcaaggggcg tttgcttgca
    12901 gaactcactg ctatggatgc cttgaaagca acgcttcctg ctggaaccgt ttctggagca
    12961 ccaaaaattc gagcgatgag acgcatctat gaactggaaa cggaaaaacg gggcgtatat
    13021 gcaggagcaa tcggctactt gtctgcgacg ggtgatatgg atttggccat tgccatccga
    13081 accatgattc tcaaaaatca aagagcctat gtgcaggctg gggcagggat tgtctacgac
    13141 tctatcgccc aaaacgaata ccaagaaacc attaacaaag caaaatctat gactagaatt
    13201 ggagaactaa gaccatgatt ttattgattg acaactatga ttcttttacc tataacttgg
    13261 cccaatacat tgggaatttt gcagaagttc aggttttgag aaatgatgat tccaagctgt
    13321 atgaagaagc tgaaaaagca gatggtctgg tcttttctcc tggtcctggt tggccagttg
    13381 atgctggaaa gatggaagac atgattcgtg attttgcagg caagaagccg attctaggga
    13441 tttgtttggg ccaccaagcc attgcagaag tctttggtgg taagctaggt ttggctccaa
    13501 aagtcatgca tgggaaacag agcaatatca actttgaagc gccatctgtt ttgtatcaag
    13561 gtattgagga tggccgtgcg gtcatgcgtt atcacagtat tttgattgag gaaatgccag
    13621 aagactttga agtgacagct cgttcgactg atgaccaagc catcatgggg attcaacata
    13681 aaaacctacc gatttatggc ttccagtacc atccagagag cattggaacg ccagacggct
    13741 tgtcttctat tcggaatttt atcgaggagg ttgtaaagtg aggaaactag gatgaaagag
    13801 attattgaaa aactagcaaa atttgaaaat ttatcaggtg tggaaatgac ggatgtcatt
    13861 gagcgtatcg taactgggcg tgtaactgaa gcgcagattg cttctctcct cttagctctt
    13921 aagatgaagg gggaaacacc tgaagaacgc acagccattg cccaagtcat gagaggacat
    13981 gcccagcata ttccaactga gattcatgat gccatggata actgtggtac aggtggggac
    14041 aagtctttca gttttaatat ttccacaact gcagcctttg tcttggctgg tggcggtatt
    14101 cacatggcca agcatggtaa ccgctcgatt tcttctaaat ctggttccgc agatgtcctc
    14161 gaagccttgg gaatcaatct tgatctcaaa ccagctgaac taggtaaggt ctttgataaa
    14221 actggaatcg tctttctctt cgctaaaaat atgcacccag ctatgaaata catcatgcca
    14281 gctcgtttgg aattgggaat tccaacgatt atgaacttga ctggtccact gattcatcca
    14341 atggctttag aaacacagct tcttggaatt agtcgtccag aactcctaga aagtacagct
    14401 caggttttga aaaatctggg tcgcaaacgt gccatcgtgg ttgctggacc agaagggttg
    14461 gatgaagctg gcttgaacgg aacaaccaag attgcacttc ttgaaaatgg cgaaatcagc
    14521 ttgtcaagct ttactccaga ggatttggga atggaaggct atgctatgga agatattcgt
    14581 ggtgggaatg ctcaggaaaa tgcagaaatt ttgcttagcg ttctgaaaaa cgaagcaagt
    14641 ccattcttgg aaacgacagt cttgaatgct ggtcttggtt tctatgctaa tggtaagatt
    14701 gatagcatca aggaaggagt tgccttggcc cgtcaagtga ttgctagagg caaggccctt
    14761 gaaaaactca gactgttaca ggagtaccaa aaatgagtca ggaattttta gcacgaatct
    14821 tagagcagaa ggcgcgtgag gtggagcaga tgaagctgga gcaaatccag cctctgcgcc
    14881 agacctatcg cttggcagaa tttttgaaga atcatcagga ccgcttgcag gtaatcgctg
    14941 aggtcaagaa agctagccct agtttgggag atatcaatct cgatgtggat attgtgcaac
    15001 aggcccagac ttatgaagaa aacggagcag tgatgatttc ggtgttgaca gatgaggttt
    15061 tctttaaagg gcatttggat tatctacggg aaatttccag tcaggtagag attccgacgc
    15121 tcaacaaaga ctttatcata gatgaaaagc aaatcatccg cgctcgcaat gcaggtgcga
    15181 cagttatctt gcttattgtg gcagccttgt ccgaagaacg cctcaaggaa ctgtatgact
    15241 acgcgacaga gcttggtctg gaagtcttag tggagactca caatctagct gaactagagg
    15301 tagcccacag acttggtgct gagattatcg gggtcaacaa ccgcaacttg actacctttg
    15361 aggtcgactt gcagaccagt gtagatttag ccccttactt tgaggaaggt cgctattaca
    15421 tttctgaatc tgccattttc acagggcagg atgcggaacg actagcccca tactttaacg
    15481 gaattttggt agggacagct cttatgcagg cagaaaatgt ggcccagaga atcaaggagt
    15541 tgcagattga caaaggttaa aatttgtgga ctatcgacca aagaagcggt ggaaacagcc
    15601 gtttcagcag gagccgacta tatcggtttt gtctttgcac ctagtaaaag acaggtgact
    15661 ttagaagagg cagctgagtt ggcaaagctt attcctgcag atgtgaaaaa ggttggagta
    15721 tttgtttcac caagtcgggt agaactgctg gaagcgattg acaaagttgg cttggacttg
    15781 gttcaagttc acggtcaggt ggcagatgat ttatttgaga atttgccttg tgccagtatt
    15841 caggctgtgc aggtagatgg aaatgggcat gtccccaatt ctcaggcaga ttatctactc
    15901 tttgatgccc ctgtggcagg aagtggccag tcctttgatt ggggtcaact ggatacgact
    15961 ggactagcac agcccttctt tatcgcaggt ggccttaatg aagataatgt agtaaaagca
    16021 attcaacatt ttactcccta tgcagtagat gtatcgagtg gagtggagac agatggacaa
    16081 aaagatcatg aaaagattag aagatttata gagagggtaa aggatggcat atcaggaacc
    16141 aaataaagat ggattttacg gaaaattcgg cggacgtttt gtcccagaaa cattgatgac
    16201 agcagttttg gagttggaga aggcctaccg tgaaagtcag gcagacccaa gtttccaaga
    16261 ggaattaaac caacttttgc gccagtatgt gggacgtgaa attccccttt actacgcaaa
    16321 aaatttgacc cagcatatcg gcggagccaa gatttatctc aaacgggaag accttaacca
    16381 tacaggagcc cacaagatta acaatgcctt aggacaagtt tggcttgcca aacgcatggg
    16441 taaaaagaaa attatcgcag aaacgggtgc tggtcagcac ggtgtggcaa ctgcaactgc
    16501 tgcggccctc tttaacatgg aatgtaccat ctacatgggt gaggaagatg tcaaacgcca
    16561 agccctcaat gtcttccgta tggagctttt gggagctaag gtcgaggccg tgacagatgg
    16621 ttcgcgcgtg ctcaaggatg cggtcaatgc agcccttcgt tcatgggtgg ctaatatcga
    16681 cgatacccac tatatccttg gttctgcctt ggggcctcat ccatttccag aaatcgttcg
    16741 tgacttccaa agtgtcatcg gtcgagaggc taaacaacag taccgtgact tgacaggtcg
    16801 agatctgcca gatgccctag tagcctgtgt tggtggtgga tctaatgcta ttgggctctt
    16861 ccatcccttt gtagaagatg agtcagtagc catgtatgga gctgaagcgg ctgggcttgg
    16921 tgtggataca gagcaccacg ctgctacctt gaccaagggt cgtccgggtg ttcttcacgg
    16981 ttctctcatg gatgtgctcc aagatgccca tggtcaaatt cttgaagcct tctctatctc
    17041 agcaggtttg gactatcctg gtatcggtcc agagcattct cactaccacg atatcaaacg
    17101 tgccagctat gtccctgtga cagacgaaga agctttggaa ggatttcaac tcttgtctcg
    17161 tgtggaaggg attatcccag ccttggaatc tagccatgct atcgcttttg cggtgaaatt
    17221 ggccaaagaa cttggaccag aaaagtctat gattgtatgc ctatcaggtc gtggggacaa
    17281 ggatgtggtt caagtcaaag accgcttgga agcagatgca gcaaagaagg gagaagctca
    17341 tgcctaagac actaacagaa aaattaaatg ctataaaagc agctggaaaa ggaatttttg
    17401 ttccctatat catggctgga gaccacgaga aaggtttgga tggactagga gaaacaatcc
    17461 actttttaga agatttgggt gtctctgcaa ttgaagtggg tattcccttt tcagaccctg
    17521 ttgcagatgg acctgttatc gaagaagctg gcttgcgcag tttagcccac gggacctcta
    17581 cccaggcttt agttgaaacc ttgaaaacca ttaaaacaga gattccactg gtcatcatga
    17641 cctacttcaa ccccctcttt cagtacggtg tggagaactt tgtcaaagat ctggctgata
    17701 cagctgtgaa gggcttgatt atcccagact tgcctcatga acatgccaac tttgtagaac
    17761 catttttggc agatacagat atcaccttga ttcctttagt aagcttgacc acaggaattg
    17821 agcgccagaa agagttgatt gaaggggcgg agggattcgt ctatgccgtt gccatcaatg
    17881 gagtgacagg gaaatcaggc aattaccgtg cagatttgga caagcacttg gcgcaacttc
    17941 atcaagtggc cgacatccca gtcttgacag gttttggtgt atctagtcaa gccgatctgg
    18001 aacgcttcaa tgcggtgtca gatggtgtta tcgtcggttc gaaaatagta aaagctctcc
    18061 accaaggaga gccgattcag gactttatca aacaagcagt agcttaccaa aaataatcaa
    18121 acaagtagca agtaagagga aaggaacgaa aggaagtctt tcctttttct tttgcaggag
    18181 aaaggctagt tttatagtaa attgaatctg gaatattaca ctacggttcc taaaatattt
    18241 ttagaaagtg atttgaattt cccaataaat ttgttcagtt tttaattgat tttactatag
    18301 aagatataat tttctaaatt actctgacac agaactttaa gaaaaagcta attattgtag
    18361 taatttcttt aagaaaatga tataattcat taaaaagtat ttggaggagg aagaattatg
    18421 ttgaatcagg atctctttga ttcgcttgag gcacaaaaaa ttgtagatac tttgatgaaa
    18481 gggcaaaaag attatgtaga tgaacgtcta gaaaaaagag agacaatgat agtgtcgaat
    18541 ggttatgcat ggacgcgacc taatcatatt gatactgcat ttgcatcagc agatttgttt
    18601 gagtataaat tacaattagc aggacagact tggggatatt tagaatttga aacaaacaca
    18661 gaaaaatatg ggaaagtatt gttaattata aagggtaaga agcgacttac gaaccaattt
    18721 cctttggtac aaaaaaataa gagtggctac ttatttgaat atgctcagat gaatacactt
    18781 tatcttaatc aacattcttc ctacaaaaat gatgaagata gtcattcctt tccaattcag
    18841 atggagttag tttctgatga aatgattcaa gaaattgaac aagctactaa aaattcgaat
    18901 atcgaaaaat ttatgatttt aacttatgag gcggactcag aaaacaatat tatatctgta
    18961 gatgttgtta tgcctgatgc acgaactggt cagttacact tgattcaaga tttgtctgag
    19021 tatattcaat caagttcgta ccatttcgaa gaagctaaat atcaagatat tcctaatttt
    19081 tcagaattat cggaaacaga agattttgaa attattccaa gaatagaaaa acaagaaggt
    19141 caaaagtagt aaggagtatg taaatgttta atggtcgggt attgaaagaa ttacggctgt
    19201 taaatggttt aagtagagca gaattagctc agagaattaa tttaacggaa caagccattt
    19261 ggcagtttga gtccaacgaa acgaaaccta aattatcaac caaaatgcat ttggccaacc
    19321 aatttcatgt tgatttaact tattttgaac aggaagaaga gagcattcga tttgattctt
    19381 ctgtaattgc ctttagaaat gcagacctag caacccggaa aacaatagat attcaaacta
    19441 tgtatttaca taaggtagat agtttgattg attattttga aagttttgta attataccta
    19501 atattacaat tcatgaccta agtaatgtag tgagtgaatc ttatcataag ggagaatcca
    19561 ttgaggaatt ggctctttat gccagggaaa aattaggtat ttcaaaagat aatcatgatt
    19621 tgctttataa attagaacgt tcaggcatct atatcgtgga acgattaatt aatggccaag
    19681 ctgatgctta tagcgcatgg tcaaaattgg gaagacctta tattgtgttg ggaacgaata
    19741 aatcatctgt acgtcgaaat tttgatttag ctcatgagct aggacatatt cttttacata
    19801 aatataaaga tatgaatgaa gatggcgatc gtttggagca agaagcaaat tattttgcat
    19861 catgtttttt attgccaaaa gaagagtttt tagtcaaatt tgaagagagg gttggcaagc
    19921 gtgtcagcaa tcctgatagt tatattttat tgaagtcgga tttgaatgtt tcgatacagg
    19981 ctttagagta tcgagctttt aagttaggat tattgactcc aaagcaacat tcttactttt
    20041 atcgtcaaat tgcgcaaaaa ggttacaaaa tgattgaacc tttggatgat caaatttttg
    20101 ttaaaaaacc aagcaaagta aagagtattc tggacgtcgt tttgagtaat catctagtca
    20161 gtctagcgac tataatgtct aaacaaagta ttcgtttaca gtttataagc gaaatatttt
    20221 cagtcgaaat gaaatttttt gatcagtatc aagaagatag aagaacagat cgatttgata
    20281 acatcatccc tttgtacaaa agaaataatt tataatttaa ctgtgaaata atttcatgga
    20341 gtacatatgg cagaaattgg aatttatcaa acaagtagta gcttaccaaa aataatcaaa
    20401 caagtagcaa gtaagaggaa aggcacgaaa ggaagtcttt cctttttctt ttgcaggaga
    20461 aaggccagga tacccgtcgc agaagcgaac tgaatcaaga tcagtaactc cgttacgcta
    20521 aagacgagag cacaagaagc taaaaagagg aaatcccctg cacccatgcg gatatcaata
    20581 aaatgagcca aaattccaag tatgaggaag gagaccatga ccagattcca gccagaggaa
    20641 gctattagga ttaggtggaa agtcatccag accagtaagg gatattcctg atggtgaaag
    20701 tcgtatatac ccaaggtcaa accagcggtg attaggacga cttgccccaa ggaaagcaat
    20761 tcccaagagt aaagcagaaa gaggagtcct aagcctagtt caaagagggc ataccagaca
    20821 ggatagcgaa ctttgcagta gcgacagcga aagcgattga agacctgtga gagaatcgga
    20881 atcaaatcta agggacgcaa gggagtctga caggaatcgc agtgactggc tgaactgata
    20941 atggattgct ctggaaaacg gtcaatgacc aaaccaagaa aggaagctag aatgctcccg
    21001 acgagaaaaa aataaaaatc aatcatactt atctattcgt aaaaaatggg agaaatagta
    21061 taatggagaa acatagataa gatggtgagg aaaagatgac aattcgtttt gaagaaaagg
    21121 tgagtataga aaacgctcaa tttgtatgcc agtggtccaa ctccctaggc aaatcctttc
    21181 aagaacaatg gatgggacca aggattcctt ttctactgcc ccttcaagcc ttggaaggag
    21241 tcttttcaat ctttgatgaa caagagtttg tgggacttat ccagaaaatc aggctagaag
    21301 acagcaatct tcatatcggg agatttttta tcaaccccca gaaacaggag caagacttag
    21361 gtagccaggc tttaaggaaa tttgttagtt tggcctttga aaatgaagat atagatagta
    21421 tttctctaaa tgtcttcgag gcaaatcaaa gagctcagaa tctttaccaa aaagaaggat
    21481 ttgaaatcgt tcaaatggtt gaagcacctg tacgaaaata tagtggattg aaactagaat
    21541 agtacacctc tatttctaaa acattgttag aaatcgattt gactgtcccg atcgattcgt
    21601 cctgttatta tttcatttca ctatacatta tgaaaaaggg gagataggag tataattcca
    21661 aatataaaga aagcgaacaa aacagaattc tgattttcag aaaacaggtt tattcgcttt
    21721 ttatgatata ctccctcttt ttagcctatt tattaaatgt aatagaaaat taagaatgta
    21781 gaattgtatg atacaaacaa agtgcaatag ctgagtgtgc ggctgtaaaa tcattgtaag
    21841 gttcaataat gacttcaggt aggcgattat agagcagttt gggtttgtag ttcatttcac
    21901 tatatagttt ttggatgatg tgttgatttg ttagtaaagg actatgtagg tagatttttt
    21961 gagagtcaat catcatactg atatttaaaa tggtttgact aagatagagt aaggcttgat
    22021 ggataagtgt gattattcca gtgtcaccta attgataagc ggttaaaata acttggatat
    22081 caatatcatc ggcatttttg actaaactag gaagtagaga atagggagat tgatgatata
    22141 gaatttttga ttttttgatt aaccaagatt ctccagcaaa agtttgtaag catcccttgc
    22201 gcccgcagct acattcttct ccctcagatg aaacaactgt atgccctatt tctccaatca
    22261 ttagatttcc tttcccataa atgtttccgt cgtagatata agaacagtgc atacctctag
    22321 caaaatgaaa ataagcaaaa ttagggtcat tctgttggcg actaaatagg cgtttaccta
    22381 tagccataca gttaacattg ttagagaaaa acaaaggctt atcaaagtgg gattgaatca
    22441 tttctaagtc gatatgttgc cataaaggat tgtttgttgt tattttataa tcatctaaat
    22501 agcgaccagg tagcgcgatt ccaattgctt ctatttcata atcagagcag ttatttaaga
    22561 attgctttag tgtctggtta atgagttgat ttcccttttc ttggattaac tgtttagtaa
    22621 caatttcttt ctcttccttt aagatatttc ctagattatc tcctaaagca aaagtgaaat
    22681 gtttttcaga tagttcacaa ccaatgtagt aaaatcgttt agcttgaatg tctagcagga
    22741 ttttttttct ccctacgctt gtatcgtgtt cgtcttcacc aagttctaag agaatatttt
    22801 ctttaatcag atcatttgtg atactgctag ttgttgcagg tgttattcct gttttagtag
    22861 cgatttcaat tcgtgaaatg ggacctaatg tgtaaactgt ttccagtatt ttagctctta
    22921 gttgtaattg tttcttagat aaggtcatat tagttttctt cctagttgtc agattcttaa
    22981 aatcctatga ttttttgcta tggataaatg tagatgttaa tctttttaag cttttcattg
    23041 cttactggtc tctttttatt atatattgat aataaaaaat aatcaaatat ttacacaaat
    23101 ccttgacaag gctttcttat agttgtaaaa tataaataac aaaagataat caaataataa
    23161 cttgacgtca aaaaataaag ataattgata acttttgata ataaaatata tttaagagga
    23221 aaaggttatg gaaaaattat tacaagaaaa gttacttcca gtagcggcta gattgggtaa
    23281 taataaagcg ttggtttcta ttcgagacgg tattactcta actatacctt tattgttgat
    23341 aggttcatta ctaatggtta ttgcaagttt tcctattcca ggatgggaaa aatatctagg
    23401 tgatattggt gttgctgact atttatggaa gggtgttgat agtagttttg gattacttgg
    23461 tcttgtagct agttttggta tcgcttactt tatggctaga caatacaaag ttgatggtat
    23521 tcctgctggt attgtgtcat tatcatcttt tattacagtt acgcctttca ttacaggaga
    23581 ggctggagca ggaatgccta ccgctttcat ggcatcaaaa ggtttatttg ttgctatgat
    23641 tttaggattg attaatggct atatctacca atggtttata aatcataata tacagataaa
    23701 aatgccggat ggtgttccac cagcagtatc taaaagcttt agtgccatta ttcctggtgc
    23761 agtgactatt gttggttggt tgattgttta tgcaacttta gataaattaa gtttacctaa
    23821 tcttcatgaa attgctcaag gagctttggg aggtccactt ggacttttag gaaataatgt
    23881 tattggtctt cttatcttaa ttttccttaa tagtagtttt tggtttgtag gattacacgg
    23941 aggaaatgtt gttaatgcag ttatgaaacc gttatggtta gctaatctag atgcaaataa
    24001 agtagcttat caaactggag aaactcttcc aaatattttt actagcgtat ttatggataa
    24061 ttttgtattc ataggtggcg gtggtgcaac cataggttta gttcttgcgt taggatattt
    24121 agcacataag aagaaagcta gtaaacaact aaaaactttg gcacctataa ctgttatacc
    24181 tggattattt aatataaatg aaccagcaat gtttggcgtt cctattgttt tgaacatttt
    24241 gttactagtt ccatttatct tagctccaat gtttaactta ctagtagcgt ggggagcaat
    24301 ggcatcaggt ttggttccgc taacttatac agatccaagt tggactatgc cacctgttat
    24361 aagtggttta cttgctacag gaagtatttc tggttcatta ttacaaattg tattgattgt
    24421 tttggatgtc ttactttatt taccatttgt aatagctatt gaaaaacggt ttaagttatt
    24481 ggaggattga gaatgaaacg tttaattagt gcaaatccat ctgagatatt acagatgaat
    24541 gctgaagaat taaaacaaag tattttagca agtgaaggta gagttgttct atctgaaaat
    24601 gtagttactc gtgagacatt tgttggggat ataactaatt ctgaaattgc tagagctttt
    24661 ggagctgata tgattttatt gaattgtgtt gatgtttttg agcctaaaat ttatgctttg
    24721 gatagttcag gtgatgatgt tattcatcgc ttacaccagc ttgttgcttg tccaattggt
    24781 gtaaatttgg aaccgattga cccatctgca aagatgctag aggaaacaca ggaaattgtt
    24841 gcgggtcgtg ttgctagtgt tgaaacattg aagcgaatag aggagttagg ttttgacttt
    24901 gtctgtttga ctggaaatcc tggaacagga gttagcaatc gagaaatcat taagactgtt
    24961 caaactgcta aggaaaactt ttctggtttg attattgcag gtaagatgca cggggcagga
    25021 gtgaatgagc ctgtggcaga gctttctgtc gcagagcaat tgttggaagc aggtgcggat
    25081 gtgatacttg ttccagcagt tggaaccgtt ccagcctttc atgaccaaga gttgcgtgaa
    25141 gtcgttgatc tcgttcatag taagggtggg ctagtactga gtgctattgg tactagccaa
    25201 gaaacatctg atacagatac tatcaaggaa attgcactta gaaataaaat ttgtggagtt
    25261 gatattcaac atataggtga cgcaggatat gggggactgg caacagtcga taatatttat
    25321 gcattgagca aggcaattag aggagtgaga catacagtat ctcgcttggc taggtcagta
    25381 aataggtgat aaaggagtaa gctatggcta aagtaacaat tatgttagcg tgtgcagcag
    25441 gtatgagtac aagtctgcta gtgacaaaga tgcaaaaggc agcagaagat aaggggttgg
    25501 atgcagaaat ttttgcagtt ccagctcctg aagcagaaga aattgtagca acaaaagaag
    25561 taaatgtgtt gcttttaggt cctcaagttc gctatttact aggggacttt caagaaaaac
    25621 taaaagatag acagattcct gtggcggtta ttccgatgac agattacgga atgatgaatg
    25681 gttctaaagt cttagattta gctgaaagtt tattagacta agattgagga gaatgctatg
    25741 aatgaaagta atttagaatc tgtaatgggg ctaattatgt atggtgggga agccaaaagt
    25801 aatgctatgg aggctattca ggcagcaaaa aaaggtgatt tctctaaagc caatcgaaga
    25861 ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga aatgttgaca
    25921 aaagaggcac agggggaaga aacatcaatt agcctcttga tggtacacgc gcaagatcat
    25981 ttaatgacga gtctgacctt tgttgacttg gcgaaagaag tggtagaagt atacgaacga
    26041 tttgaaaaaa attaggaatt tgctatgaat acaatgttgg ataaaatgca agaaaaactt
    26101 tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg tgattcattt
    26161 gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa tgcttttcta
    26221 gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca gtggcttgtt
    26281 gacatcaata atttggtatt caagggaagt ataccaattg tttccttatt gttcatctat
    26341 tgcttgggag tgaatatcgc taagatttat aaggttgata cagtttctgc tggtttggta
    26401 tcgcttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt ccctttggca
    26461 aatgtaggag atgtgaaatt agatcaaatc ttacaaggaa ttgataatct agcatttgat
    26521 ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat taatgccaga
    26581 ggctacttta cagccatgat gattggattt ttagcctcta ttattttctg taaagtaatg
    26641 aaaaagaact gggtaatcaa gttaccagat tcagttcccc ctgcgattgc taagccgttc
    26701 acttctatca ttccaggatt tatggcgatg tattatagta gccatcttga cttatgtttt
    26761 ccatttactt agcaattact tattgattga ttgggtttac aaggtgttac aaacgccatt
    26821 actaggtttg tctcaaagtt tctttgcagt tattctgatg atctttttaa ataagttatt
    26881 ctggtttttt ggtctccatg gaggaaatgt attggctccc atcatggaag ggctgtttgg
    26941 agttgctatg ttagcgaatc tggatgcttt ccaaaaaggt gaaccgattc cttatatatg
    27001 gacaagtggg tcttttgggg cgtttgtctg gtttggagga ttaggattgg tacttgctat
    27061 tttaattttt tcaagaaaca gtcattatcg aaaagttgct aaacttggtc tagcaccagt
    27121 tctgtttaat attggtgagc cggtaaatta tggtttacca gttgtcttga atcctttgct
    27181 atttatacca tttgtactta gcccggtttt catggcaacg gtagcttact gggcaacaag
    27241 ctggggtctt gtttcacctg ttacacaaaa tgttacttgg gtaatgcctc caattttata
    27301 tggtttcttc tctacagcat ttgattggcg tgccatcatc ttatcagttg tttgtttgat
    27361 tattagtgtc ttgacttatt tcccatttgt gaaaatggca gataaaactg aattgagtta
    27421 atggtcttac ttgcgttttt tgtgataaaa tagaaataga ttacgtgtaa gattgagtta
    27481 ggtgtaggat ttcttatctc cactaaaatt gttattagac aaaggtttat agtttattga
    27541 agttggaata gtacactgta acttctaaaa tagtactaga aaatgatttg aatttcctaa
    27601 tcgatttagt catattttag ttcatttttc tataaaacat aacaagaatg ttattgtttt
    27661 atatagagag attgatatag aaaggggtgc agtaaaggta gatatcttct tgtgcctctt
    27721 ttgccatatt agaaaggaga ttttatggtt cagacaaaac agccaaatat tattttgatt
    27781 gttgtagatc aaatgagagc agacgcctta tccttgaata gtaaggataa gctagttagc
    27841 actccaacat tagatatgat ggctagtgta ggttataatt ttgaaaatgc ctattctcca
    27901 gttccttctt gcgttcctgc tagggcagct ttattgactg gcttagacca agataaaagt
    27961 ggacgagttg gttatcaaga tgaggtgcct tggaatttta ctaatactct tccaaaagtc
    28021 tttaaagata tgggttatca aacagagtgt attggtaaga tgcatgtttt tccttccaga
    28081 cagagacttg ggtttgatca tgtcttactt cacgatgggt atctacatgt tgatagaaag
    28141 tatgataagg cttatggaag tcaatttgat tatgctagtg actatctagc ctttttaaag
    28201 ggtaaagttg gttatgatgt tgatttgatt gatgacggaa tggattgtaa ttcttgggaa
    28261 gctagacctt gggataaaga tgagaagtta catccaacaa actgggttgt gagtgagtcc
    28321 atttcatttt tacaaagaag agatccaacg gttccttttt ttctcaaaat gtcttttgaa
    28381 aaaccacatg ctccattaaa tcccccaaaa tactattttg atatgtatat ggaacgcttg
    28441 cctcaatttc tcgatttgca tatcgggaat tgggaagtat tagaaaagca aattccgtct
    28501 atttatgctt taagagggaa attaaaggaa gatgatcaaa gaagaatggt tgctgcttat
    28561 tttggattga ttactcatat agaccatcaa attagtcgct ttttgactgc cctaaaagaa
    28621 tttcgtcatg ataaagatac gattatctgg tttgtttcgg atcatggaga tcagcttggt
    28681 gaacattatc tgtttagaaa gggatatcct tatcagggaa gtatccacat tccttcgttt
    28741 atttacgatc cggctggatt gatagctggt aataggggaa caatcaagca attagtgaaa
    28801 attcaagata tttttccttc actcgtggat ttggcaggag gaactactac agatgaacta
    28861 gatggacgga gtgttaagaa tttattattt ggacagtacg aggggtggcg aacagaattt
    28921 catggtgaac atactttagg aaaagattct agtcaatata ttttgacaga ccagtggaaa
    28981 tttatctggt ttcctgtttt aaatcattat cagttatttg atatgaaaaa agatccgcat
    29041 gaaatgaatg atttgtatcc aagtgaaaaa tatcaaccta ttgttcgtca gatgaagaaa
    29101 aaattagtag actttcttag atatagagaa gaaggttttg ttgtggatga agagttagtt
    29161 cctgttgaac tttctaaaat aacgccaact ctaacgaaaa cgggggatag tcaatcatga
    29221 aaatgaaaaa aatcaagggt gggacattta tgatgggaac aaattctgaa gagggctttt
    29281 tagatgattt tgaaggtcct caagtcgctg ttagtgtaaa ggatttttcc attgcggata
    29341 ctccagttac gaatcaagaa tttgctcaat ttgtgaaaga aacaggctat aaaacactag
    29401 ctgagcgaca agagtggtct tttgttttta tattgttcgt tccggaggca gaaagggagg
    29461 gatatcctca tcctgctggg gctccgtggt ggttacaagt ttcgaacgct tgctggaaac
    29521 atccctacgg tgagaacagt aatctagtgg gtttagaaga ccatccagta gttcatgttg
    29581 ctttagaaga tgcattggct ttctgtaatt ggagcggaat gtctttaccg actgaagcac
    29641 agtgggaata tgctgctaga ggaggaagac aatctgaata tccttgggga gatactcttt
    29701 tagaaggtgg atattatcat gccaatactt ggcaaggaag atttccttat gaaaatactg
    29761 ccttagatgg atttatagga acggctcctg tctatgaatt tttacctaat gattttggtc
    29821 tatatcaaat gattgggaat gtttgggaat ggtgtcgcaa tccgagatat accttattag
    29881 ctagttttaa tgaagatgac tatgagttac caaaatatgg gatacaagat gaggagtatg
    29941 ctatcagagg aggttccttt ttatgtcatt gttcttattg taatcgatac cgagtagctg
    30001 ctagaaatgg atgtatttct acttccacta gtagccatct aggttttaga tgtttgaaag
    30061 aataggatgg acttaaaaag tggttgagat tatttatttt ctaatcatta taatagctag
    30121 tggattgggt tctatatcag gcatgggtgg tggaattata attaagccac ttatggatag
    30181 ttttggatac cattcggtca gtgatattgc tttttattct agtttctctg tttttataat
    30241 ggcgattatt tcaacaatca aaagattttc acaaagtaaa gagataaaat ggagattgat
    30301 ttttacggta tccttttctt ctgttttagg aggatttcta ggtcatctta tttttcaagt
    30361 tttgttatat caattatcag tacggctagt atctattgtt caaatgattt tactatttgt
    30421 gatgttactt gtatcatttg ttttaacaga ttttaaaaaa acttatcaat ttgataagat
    30481 aggattctat atgatttgtg gtcttctatt gggcttaatt tctagttttt tagggattgg
    30541 tggtggtccg ctcaatgtat ctttattgat ggtgtttttt tctatttcga taaaagaagc
    30601 aacgatgtat tctcttgcaa ttattttctt ttcccagctg tctcatttgg ctacaattgt
    30661 tgtggttaca ggtttaaatc agtatcattt agcacctgtt ccagttattt ttcttgcttc
    30721 tatatgcgga ggggtattgg ggacggttgt atcaaaagtc ttacctgaaa attgggtaag
    30781 atactgtttt aaagggatgt tattctttgt catgggaatg actttatata atttatttca
    30841 tattttgtaa ggtcagtgtg aaaatattta aatagacttc ctgtaaaaac tggatttaac
    30901 gccctccatt tgtcaaatta agctagacag tcttaccaac tcagaaaata cctgatgagg
    30961 tatttggtat ccaaaggatt taggtgggat gtgatttctt gaggctggga aaaagtcttt
    31021 aaaattaaaa aatgcataat atcaggtgtt ggaaaaactt tgatactatg cgttttattg
    31081 tgggaatatt tatttcattt tctcctgaaa ttgagttttt gtccagccta aaattcttga
    31141 ctgacttcgt tgaaatctgt ctgctttggc aagtcatgac accttaaaag tctatttgaa
    31201 tgttcgttga gacgccgctg tcttgaacat cctagattcg caaaaaagct ctcactatcg
    31261 tgatgattgg aaatatcttt ccattttgaa aactcttttc cacagtcaaa cgtaatagat
    31321 ttaaagaggt tcactagaaa ttgtgccagc cacccttgga tggattctgc catatccttt
    31381 gccttacgac tcttggtctt caaactgaca atcaattgac tatacttgtt cgctcacaaa
    31441 taggagagaa ctgtttacga aaatctaatg aatatgccac aagaacatta taccgcaacg
    31501 tgtactattt ttggttcatt ttactataga aactattgaa gaacctgtac gaaaatatat
    31561 catgaaaaag gggagataga aagcaaacag ccttgaaatc aatgttgact gcgattatga
    31621 acctgaatca gcccctcaaa agggactgta tatgaatgaa cgttaccagt gtttaaaaac
    31681 taaagaatat caggcacttt tatcttccaa gggtagacaa attttcgcta aacgtaagat
    31741 tgatatgaaa tctgtctttg ggcagataaa ggtttgtttg ggttataaga gatgtcatct
    31801 gagaggtaag cgtcaagtga gaattgacat gggattcata ctcatggcca acaacctgct
    31861 gaaatataat aagagaaaga ggcaaaatta aaaagctaga gttccgcaat tgggaatctc
    31921 tagctttttg ttttctgaga atcatcttga ctcagactct tttgactaat gttaccaata
    31981 accttattta tcgtcgccac tcaacatgtt tttaacacct tctacagcac cttctacagc
    32041 gtctttagcg tcttcggcaa cttcttttac tttagaaaca actttttcag ctgctccttc
    32101 tttttccatt ttttcatcac cgatggcttt cccaacacct tctttaatag aacctttagc
    32161 ttgatttaat ttttcttcta ctgacatgat aatttctcct gttatattta ttttatctta
    32221 gtttacacga gtgttttcgt gagatactac accatttgct gcacctttaa cagcttctac
    32281 accttcgcta actttttctt gaacagttga gaaaccagat ccaagaccag atttagcttt
    32341 ttcgaattgt tctgaagtga attctcctgt tgattcagca acgtcagata cgcgatcttg
    32401 aaggcttact gagtctgctt catgctgttc tttagttttg atgtcgacaa cgtttacgtt
    32461 gatttcaaca atttccaagt cagtcatttt agcaacttct gaagatacga tttctctgat
    32521 ttctgaatat aaagctggaa catttttttg gtactcaaca ataacgttta agtcaactgc
    32581 aacttgtgtt ttaccaactt ctacgttaac accacttgtt acgtcatcgc tgttaacgat
    32641 tttttcttta agatttgaga agaaaccacc atcgattccc aaaagacctg aaacgttttc
    32701 tagtgaaaga ccaatgattt tttggataac tttatcttcg taagtaagtt cccctttgat
    32761 ttcgtgagct acaacagtag catctttctt ttctacgtta gtgtttgtgt ttttttcgtt
    32821 tgacatatga aactccttta attaaattag taatttttat ttttttattt atctatatag
    32881 tttttttcga tatataatcc agctgcaact cccagtgctc ctaaaatcaa tacaaatatt
    32941 gttttgaaga agccaaagga gacaatcaaa caagccagaa atacgcctat gagaccagcg
    33001 ataattggat atcgatattg tttaagccat tccatttttt acttccttac ttcacacgac
    33061 taacagtctt tttgttttga ggttttggtt ggtaattttt tactgcaact tcaagtttta
    33121 cttgacgctc aataccaaaa aactgcttca atccattagt tatttcattt tgaattattt
    33181 ggcatctgtc agcgatgttg tctgaaggaa gaattttacc ttctacatga acgaaacatt
    33241 tattttttcg taaatttaca tgaacagttg ggttcttgat caatctatga tcactcacca
    33301 aacttctaac aaaaccttcg attgccgaat tctttaattt taatgtatcg tttttagttt
    33361 caagttggat ttccaagtaa cgtttaggat aaaacatcac aactaaaatg gataataaaa
    33421 ctaaagttga tagaaccact gtcccccaaa agacatatct agcaagatag aattcaacta
    33481 cggagttctg tctccagctc agtagatgaa tacctagatc actaacttga tgataatcta
    33541 tcaaaacagg aaggaaaatt gtcaagatta aaatacagaa aataatgaaa catattttct
    33601 ttgcttttga catatacaat cctttcgatt taacatttaa actatttttc ccgtcattga
    33661 tttaaaaata gtttgctaac tttactggcg aaaagtttac tttctacctg taaagaatga
    33721 cactacagta atcacaatcg ctgcacctac aatagatggg agcaaagcca ttccagcgat
    33781 tgatggaccc caactaccta aaagagattg tcctgcatat gccccgacta aaccagcgaa
    33841 tacatttgcg atgattccca tagaactact tttttagtga ttttacctgc caagagacca
    33901 ataagacctc cagcaataat tgatcacaac actgcctacc ctcctttttt attttaatat
    33961 caaaaaatca atttctttga ttattactat tatataactt taatatagaa aagtcaatta
    34021 tttcgattgt tattattata taattttaaa aaatcaaatt ctttaattgt tgctattata
    34081 taatttttaa aattaaaaat ataatcttta gacttgaatt tgattctgta ttcacgccct
    34141 caatagacgg taaaataaga aaattgttta tatattgtct ccgtagtgtt attatacgaa
    34201 ataaaagatt ttaggaaaag tcgttatatc atgctatacc tattctttgt ggtataattg
    34261 caagaggttt aatccgataa tttataaaga gagaaagata ttcatgagag atttattatc
    34321 taaaaaaagt cataggcaat tagaattatt agaattatta tttgaacata aacgttggtt
    34381 tcatcgttct gaactagcag agttattaaa ttgtacagaa cgtgcagtca aagatgatct
    34441 atcccatgtt aaatctgctt ttcctgactt gatttttcat tcttctacta atggtatacg
    34501 cattattaat accgatgata gtgatattga aatggtttac catcatttct ttaaacattc
    34561 aactcatttt tcgattttag aattcatctt ctttaatgaa ggttgtcaag ctgagagtat
    34621 ttgtaaagaa ttttatatca gttcatcttc gctctatcgt attattagcc aaatcaataa
    34681 agtgattaaa aggcaatttc aatttgaagt cagtttgacc cctgttcaaa tcattggaaa
    34741 tgagagagac attcgttact tttttgcaca atatttttca gaaaaatatt atttcctaga
    34801 atggccattt gaaaattttt catcagagcc actatctcaa ttgttagaat tggtttataa
    34861 ggaaacaagc tttccaatga atttgtcaac gcatagaatg ctaaagttgc tcctagttac
    34921 gaacctatat agaataaagt ttggtcattt tatggaagta gataaagatt cttttaacga
    34981 ccaaagtttg gattttttaa tgcaggcaga aggaatagaa ggtgttgctc agagttttga
    35041 atcagaatac aatatctctt tagatgaaga agttgtttgc caattatttg tgtcttactt
    35101 tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa tgcgtaaaaa aggatagtta
    35161 tgttgaaaaa tcttaccatc tattgagtga ttttattgat cagatttcag tcaagtatca
    35221 gattgaaatg gagaataagg ataatctgat ttggcatctg cataataccg cacatctgta
    35281 tcgtcaagag ttgtttactg agtttatttt atttgatcaa aaagggaata caatcaggaa
    35341 ctttcaaaat atttttccaa aatttgtttc agatataaaa aaagagcttt ctcactattt
    35401 agagactctt gaggtttgtt ctagttcaat gatggtaaat catctatctt ataccttcat
    35461 cactcatacc aaacatttgg tgattaattt gctacaaaat cagcctaaac taaaggtttt
    35521 ggttatgagt aattttgatc agtatcatgc aaaattcgtt gcagagacac tttcttatta
    35581 ctgtagcaat aattttgaac tggaagtttg gactgaatta gaattatcaa aggaatcttt
    35641 agaagattca ccttatgata tcattatttc taattttatt attcctccta ttgaaaataa
    35701 gagactcatc tattcaaata atataaacac ggtctcactc atatatttgt taaatgccat
    35761 gatgtttatt cgattagatg agtaaccaaa aataacaaaa aacgctattt cgcgtttgaa
    35821 ctgtacctca aaagttagac agaaaaaatc taatttttgg ggtgtttttg ttaagaaaag
    35881 accttcaatc atttaagcaa aatgtacatc tagatttata gccctctaaa actcttgctt
    35941 tttttgtaga agatacgaaa aaagccataa aaccaaggct tttcctgttt tatgtagatg
    36001 tttacacatg aaaattgaag tattttcaaa agctaattgg agtgatttta ttcatgatgg
    36061 gataaatgat ctggccaaaa atgattgaga aatagttgct taaaaagcat ttgcatgata
    36121 ctatatattg aaaggaggtg ataatatggt agaacaaaga aaatcaatta ccatgaaaga
    36181 tgttgcttta gaagcaggag ttagtgttgg aactgtttca cgtgtaatta ataaagaaaa
    36241 aggcattaaa gaagtaactt tgaaaaaagt ggaacaagcg attaaaactt tgaattacat
    36301 tccagattac tacgctagag gaatgaaaaa aaatcgaaca gaaacgattg caatcattgt
    36361 accaagtatc tggcatccct tcttttcaga atttgctatg catgtggaaa atgaagtcta
    36421 taagagaaat aacaaattac tcttatgttc tatcaatggt acaaatagag agcaagacta
    36481 tctggagatg ttgcgtcata ataaagttga tggagtggtt gccattacct atagtccaat
    36541 tgaacattac ttgacgtcag gaattccctt tgttagtatt gaccgcacat actcagatat
    36601 tgccattcct tgtgtttcat cagataatga tgcaggtgga agagaagcag ctaaacaatt
    36661 aattagtaaa ggatgtcagc atttagcctt tgtgggcgga cataatacaa ccattaatga
    36721 aaccaaacgt cgtagaattt catttgaaaa gtatgtccaa gagcataaaa tacctcttag
    36781 tatttttgat ttggatgaga cagttactga ctattatgga aagctagaga gtttcttgga
    36841 agaaaattct tctatagatg gaatttttac aatcaacgat tttacagctt tggatgtgat
    36901 tgaaatacta gaaaaaaatg gcaaacgtat tcctcatgat gtccaaatta ttggatacga
    36961 tggaattaaa atggctggag atagagatta tctactttca actattgaac aaccattgga
    37021 agaaatggca aaagaagcgg ttcgtatttt gtttgatata attgatggaa agactgttaa
    37081 tttgcagaca atcctaccag taaaatttgt tgaaggaaaa acaacaaaaa atgaaaataa
    37141 gtcttgacag aaagcgctat caatgataga atgaattcag ataaaaagat ttatttttaa
    37201 aacaaaaatg aaacgtttca aaaaaagaaa taaagagaca gcgccaagcg ctatcttttc
    37261 tagaaaaaaa tgaaacgttt caaaaaggag gttgctatga atagcaaagc gaagcaagtt
    37321 tctctttggg aaagaatcaa gaaacaaaaa ctcttgttat tgatgactgt ccctggttta
    37381 gttttaacct ttatctttaa atacatccct atgtatgggg ttttaattgc atttaaagat
    37441 tacaatcctt taaaaggaat tttagggagt gattggattg gtttttctga gtttacaaaa
    37501 ttcatatcct ctcccaactt tggtatcttg ttagccaaca cattaaaatt aagtatctat
    37561 ggtttattgc ttggcttttt accaccaatc attcttgcta ttatgctcaa tcaactcttg
    37621 agtgaaaaag tcaaaaaacg aattcagctc attttatacg caccaaactt tatctcagtc
    37681 gttgttattg tcggtatgat tttcctcttc ttttcagtgg gaggaccaat caacaatttt
    37741 ctttctatgt ttggaatgaa ggctgacttc ttgacaaatc cagacttctt tagaccttta
    37801 tacatcttta gtggtatctg gcaaggaatg ggctgggctt caacgctcta cacggcaaca
    37861 ttggtaaatg tagatccagc cttagtagaa gcagcccgac tggatggagc caatatcttc
    37921 caacgaatct ggcacattga tattccagct cttaagccta ttatggttat ccaatttgtt
    37981 ttagctgcag gtggaattat gaatgtcgga tatgaaaaag cattcttgat gcagacatcg
    38041 ttaaatttgc caacttctga aattatctcg acatatgact ataaagttgg tcttgtatca
    38101 ggagactatt cttactcaac agcggttggt ttgtttaatg cagtgattaa cgtagtattg
    38161 cttgttgcag ttaaccaaat cgttaaacgc atgaataatg gtgaaggaat ttaaggagga
    38221 aagtatgaaa aattcgatta tggatacaaa atttgataga cgtatcttac tcttaaataa
    38281 aatcattatt gtctttatcg ttttgatgac tttgcttcct ttactttata tcgtcgtagc
    38341 atcctttatg gatcctaagg ttctggttag tagagggatt agctttaatc cagccgattg
    38401 gactgtagaa ggttaccagc gtgtattcag tgaccaatct attctaagag gttttatcaa
    38461 ttctctacta tactcttttg gatttgcagc tttaacagtc ttgctatctg tgtttacagc
    38521 ttatcctctt tccaaaaaag atttggtagg gcgccgttgg attaactact tcttgattgt
    38581 gactatgttc tttggtggtg gtttagtccc aacttacttg ctcgtaaaag aattgggaat
    38641 gctcaatact ccatgggcta tcattgttcc aggtgctgtc aacgtttgga atattattct
    38701 tgctagggcc tatttccaag gattgcctga agaattagtt gaagctgctg tcattgatgg
    38761 tgcaaatgat ttacagattt tcttcaaaat catgcttcct cttgcaaaac caattatgtt
    38821 tgttctcttc ctttatgctt ttgtaggaca gtggaactca tactttgatg caatgattta
    38881 tatcaaggat ccaaacttgg aaccattgca acttgtactt cgtaaaattc tcattcagag
    38941 ccaaccaggt caagacatga ttggagcaca agcggctatg aatgaaatga aacgtttagc
    39001 tgaattgatt aaatacgcaa ctattgtcat ttccagcttg ccattgattg ttatgtatcc
    39061 attcttccaa aaatactttg ataaaggaat tatggctggt tcacttaaag gataaaaaaa
    39121 gaaaaaataa aaggagtttt ctcatgaaat tcaaaacatt ctcaaaatca gcagttttgt
    39181 tgacagctag tttagcagta cttgcagcct gtggctcaaa aaatacagct tcaagtccag
    39241 attataagtt ggaaggtgta acattcccgc ttcaagaaaa gaaaacattg aagtttatga
    39301 cagccagttc accgttatct cctaaagacc caaatgaaaa gttaattttg caacgtttgg
    39361 agaaggaaac tggcgttcat attgactgga ccaactacca atccgacttt gcagaaaaac
    39421 gtaacttgga tatttctagt ggtgatttac cagatgctat ccacaacgac ggagcttcag
    39481 atgtggactt gatgaactgg gctaaaaaag gtgttattat tccagttgaa gatttgattg
    39541 ataaatacat gccaaatctt aagaaaattt tggatgagaa accagagtac aaggccttga
    39601 tgacagcacc tgatgggcac atttactcat tcccatggat tgaagagctt ggagatggta
    39661 aagagtctat tcacagcgtc aacgatatgg cttggattaa caaagattgg cttaagaaac
    39721 ttggtcttga aatgccaaaa gctactgatg atttgattaa agtcctagaa gctttcaaaa
    39781 acggggatcc aaatggaaat ggagaggctg atgaaattcc attttcattt attagtggta
    39841 acggaaacga agattttaaa ttcctatttg ctgcatttgg tataggggat aacgatgatc
    39901 atttagtagt aggaaatgat ggcaaagttg acttcacagc agataacgat aactataaag
    39961 aaggtgtcaa atttatccgt caattgcaag aaaaaggctt gattgataaa gaagctttcg
    40021 aacatgattg gaatagttac attgctaaag gtcatgatca gaaatttggt gtttacttta
    40081 catgggataa gaataatgtt actggaagta acgaaagtta tgatgtttta ccagtacttg
    40141 ctggaccaag tggtcaaaaa cacgtagctc gtacaaacgg tatgggattt gcacgtgaca
    40201 agatggttat taccagtgta aacaaaaacc tagaattgac agctaaatgg attgatgcac
    40261 aatacgctcc actccaatct gtgcaaaata actggggaac ttacggagat gacaaacaac
    40321 aaaacatctt tgaattggat caagcgtcaa atagtctaaa acacttacca ctaaacggaa
    40381 ctgcaccagc agaacttcgt caaaagactg aagtaggagg accactagct atcctagatt
    40441 catactatgg taaagtaaca accatacctg atgatgccaa atggcgtttg gatcttatca
    40501 aagaatatta tgttccttac atgagcaatg acaataacta tccaagagtc tttatgacac
    40561 aggaagattt ggacaaaatt gcccatatcg aagcagatat gaatgactat atctaccgta
    40621 aacgtgctga atggattgta aatggcaata ttgatactga gtgggatgat tacaagaaag
    40681 aacttgaaaa atacggactt tctaattacc tcgctattaa acaaaaatac tacgaccaat
    40741 accaagcaaa caaaaactag aggttgatta tgggagataa gaaatacaca gtagaaaaag
    40801 ccaatcgttt tatagcagaa aataaacatc tcgttaatac tcaatataag cctgaagaac
    40861 atttttcagc tgagattggt tggatcaatg atccaaatgg atttgtctat tttcgtggag
    40921 aataccatct cttttatcaa ttctatccat atgatagtgt ttggggacct atgcactggg
    40981 gacatgctaa aagtaaggac ttggtgactt gggagcactt gccagtggca cttgctcctg
    41041 atcaagatta tgaccgaaat ggttgtttct caggctctgc cattgtcaag gatgatcgcc
    41101 tctggctcat gtacactggg catatcgaag aaaaaaccgg tgtccgccaa gtgcaaaata
    41161 tggcattttc agatgacggg attcactttg aaaagatttc ccaaaatcca gttgcaactg
    41221 gatcagactt gccagatgag ttgattgctg ctgatttccg tgatccaaaa ctctttgaaa
    41281 aagatggacg ctattactcc gtagtagctg ccaaacacaa ggataatgtg ggctgtatcg
    41341 ttctactagg gtccgataac ctagtagaat ggcagttcga atccatcttt ttaaaagggg
    41401 gagaacacca aggctttatg tgggaatgcc cagattactt cgagttagat gggaaagatt
    41461 gccttattat gtcacccatg cgttatcagc gtgagggaga ctcatatcat aacatcaact
    41521 catcgctttt gttcacgggt aaggtagatt ggagagaaaa acgttttatc ccagaatcag
    41581 ttcaagaaat tgatcatggc caagacttct atgcgcctca aacattgttg gacgatcaaa
    41641 atcgtcgtat cctgattgct tggatgcaga catgggggcg tacccttcca acccatgacc
    41701 aagaacacaa atgggcatgt gctatgactt tacctagaat tctaagattg gaagatggca
    41761 aactaagaca attccctgtt aaaaaaggcc aatatcaaat ccaaatagat aaagattgtc
    41821 attaccactt aggaaatgat acagattatc ttgaatttgg ttatgacagt aatgcgcagc
    41881 aagtttacat tgatcgtagc catcttattc aaaaaattct aggtgaagaa gaacaggaca
    41941 ctagtcgacg gtatgtagat attgaagcta aagaattgga agttgttcta gataaaaatt
    42001 ccatcgagat ttttgtcaat caaggtgaag caagcttgac tgcaacttat tacttaacgg
    42061 tgccagctga gctatcacga attgattaaa aattaagtta tttctcctaa agaaaaagtt
    42121 ctctttctaa aatagtggaa agaggacttt ttgtgttttg ggtatataag cttagtttat
    42181 ggtatttgta aaattggtgt tggattatga tttaagctag ttttctaaag aatttgaaaa
    42241 aaattttatt taagcaaaaa aaccttggtt ccaaggcttt tcctgttgta tgtagatgcc
    42301 ccctacaggg atcgaacctg tgacccacgg attaagagtc cgctgctctg ccagctgagc
    42361 taaggaggca aagaaaaaag ctgtattggt gccgaaactt cacggtttgt attgaacccg
    42421 cgcaattaag caggtgggca actcgctcta actgaagctg tttccgtgtg agacggccta
    42481 catgctgtta gaagactttt gtttccctaa taatacaaaa aatagtcggt caacacttaa
    42541 gtgtgaagtc gtacaccaca gcgtttctat acttatatga taccactttt tcaaaaaaaa
    42601 tcaagaggaa agtgcaattt tttgaaaagg atttcagatt tttcgcaaac gatcgatagc
    42661 ttcctttctt tgagccaaag cccgttcata tttaccagta tcttctgctt ggaaatagtg
    42721 atgattacga attttttctg gcagatagtc ttgcttgatc caatttccag gatagttgtg
    42781 tggatagaga tagtcttggg cattccccag ttccttgctt ccactgtagt gcccatcacg
    42841 caggtgtcgc ggaataggca agtgccctga tgttttgagg tcagcaagtg ccttatccat
    42901 agctacatag gctgagttgg attttggaga aagggccaaa tcaatcacga cattggcaat
    42961 gagaatgcgg gcttctggga acccaatctt ctgggcagca tccagagcag tcacggtatg
    43021 aatctgggcc tcaggattgg ctaagccgat atcttcatag gcgataacag tcaagcgacg
    43081 agcgagacta ggcagatccc cagcctcaat caagcgggca gtatagtgga gactggcatc
    43141 cacatctgag ccacgaatag acttttgcag ggcagataga acatcatagt gaccgtctcc
    43201 atccttgtcc atagtgatgt agcttctctg aagactattt tccatgatgt ctaaggtgat
    43261 gtggcgaatg ccctcgtcat tctcaggggt agagagaaca gctaagtcca gtgagttaaa
    43321 ggcagagcga aggtctccgt ttgtagaggt tgcgatgaaa tccagcgcat cctcatctag
    43381 ttctattgga aaatcaaaac cacgttcagg gttacttaga gctatctgca gggcctcttt
    43441 gacgtcttgg ttagacagag gttccaactc gaaaatttga actcggctac gaatggcagg
    43501 agtgacagag aagaaaggat tttcagtcgt tgctccaatc atgatgacca gtccactttc
    43561 caagagaggc aagaggaagt cttgcttggt cttatctagt cgatgaattt cgtctagtaa
    43621 taggacgaga ccaccagaaa atttagcttc ttccgagatt tcttgcagtc gctttttact
    43681 atcaactgtc gcattgaaag ttcgaaaggc atacttggtc gttccagcga tggcagaggc
    43741 aatactggtt ttgccgattc caggagggcc atatagaatc atggaggaca ggcggttggc
    43801 ttccaccatg cggcggatga tttttccagg tccgaccaga tgctcctgac cgatgacctg
    43861 gtcgatggtt ttagggcgca tgcgaagcgc gagattgtct ggcatagcag tcctttctaa
    43921 cgtggatttg agtagaatga ctcatctact atatcttact atgtccattc tagcctatta
    43981 gttgtgatat ttcaatggtt ttgtaataat cagggagtga gatagaatct tttttactat
    44041 ttaatttaat gaggagaggt atcagcatga gagatttgat tttccttaaa gctcaaaata
    44101 ggatagttga gcctaaagaa gtggaagtgc tgacttgaga aataatattg ctgaatgtca
    44161 ttgtatgaac tataatgaaa agagaggtga taagcaatgg aaatgatgga actaccaagt
    44221 caggaaattt tgatttttac aaaacaaatt cgtcattgga ttcttagtga tcaagttatt
    44281 tcagggaaaa gaaaactttt cttccgggaa gatactccaa aagagatttt agatttgtac
    44341 gaaaacatta aatctaaact tgattttgct taccaagaag ttcattctaa taatgggttg
    44401 aaaaaatatg aaaaatagaa taattgatgt ttttgaagta gtaaatcgcc tccttgtaat
    44461 aactgttgaa aatcctgatt tcgaagactt gagagttaat catactcaat gaaaatcaaa
    44521 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggtaaggcga cgttgacgtg
    44581 gtttgaattt gattttcgaa gagtatcagt ttgtaaaaat tggagataaa aaatatagag
    44641 tacgcagtgt tcctatgatt cattcaactc cgcctcaatc tgtcttagat cgagatactt
    44701 ttacaattga ctatacagat gatgaattgc tcgataaaga agcagttttt actactcatt
    44761 agaaaaatag gtatgaataa attggcttcc cttagaacca catctagggg cttttatgta
    44821 taatagaata ataagtatca ctcctttaca atacgtgtaa cacgtgttat aatggtgttg
    44881 tcaggaggta aaagcgctat gcctatgaca caaaaagaga tggttaaact ccttacggcc
    44941 catggttgga taaagactag aggcggtaaa ggctcccata ttaaaatgga aaagcaaggg
    45001 gaaagaccta tcacaatcct tcatggtgag ctgaataagt acactgaaag agggataaga
    45061 aagcaagctg ggttgtaaaa ttcagcccct gctttttgat atggaggtag tgaaatgtta
    45121 gttacgtatc cagctttatt ttattatgac gacacagacg gaacagaagc gacttatttt
    45181 gtccatttcc cagattttga atactcagct acacaaggag aggggatttc tgaggctttg
    45241 gctatggggt cggagtggct agggataact gttgcagatt tgatagagag tgatggagag
    45301 ttacctcagc catcagatat caatagcttg tctttaattg ataatgatcc ttttaaagat
    45361 gatgaagatt tcgtgtcaac ctatgacctt gataaatctt ttatttctat ggtatctgtt
    45421 gatgtatcag aatacctagg aagtcaggaa cccattaaaa agactttgac cataccaaaa
    45481 tgggcagata agttgggacg agaaatgggg cttaactttt ctcagacttt gacagacgct
    45541 attgcagata agaaagttca agcctaagat taagcgtggt atcgtggtaa tagtcaataa
    45601 aaaagcacgt ccacttgtgc tagttactcg cctattgatt ttatagattt attagccctt
    45661 tcgagggctt tttatattga tttttatgag aaatgaagaa atcagacttt taagaaaatc
    45721 actgatacca agggtttaaa tgaggtaata tggtataatt aggacataaa ataattttgt
    45781 ggtaagatgg tagtatctat tttagcatat ttccgagcaa tcggggcgat taaagagtcg
    45841 catagaaaga ggacaaaatg gcaacatacg gatttttaga tattttagag gaagagttgg
    45901 acaagaactt tccctttgac tttgagatta gctgggacaa acgcaaccat gcggtagaag
    45961 tgagttttct attggaagcg caaaatgctg caggtgtgga gatggtggat gaagacggag
    46021 aggtttcatc agatgacatt ctttttgagg aagcggtcct tttctacaat cctgccaagt
    46081 caacagtcaa tgaggaagac tatttgactg ttattcctta cctgcctaaa aaaggatttt
    46141 cccgtgaatt tttagcttat tttgcgcttt tccttaaaga tactgctgag gttgggctag
    46201 atgtcctcat ggactttttg gaagacccag aagcagagga atttgtcatg gaatggaacc
    46261 aagaagtctt tgaagaagga aaaattggct tggaaaaggg agaattttat ccttatccaa
    46321 aatactagga gttggttgga ggtgttatga agaaaattgg gacttatttg gtttatgtgc
    46381 tagctgttgt ctttattatg ctagcttttg cttgtggaac aatcgcattt gcagagttgg
    46441 ggtattccgc agttttagcc tttacttttg gttatgcctt cgctcttcta agcatgtatt
    46501 taatctttat tcttcatgag ctgggtcatg ctttttgtgg ctacttgaca ggctatcggc
    46561 tggtggcttt tggattagga cattttattt tgaccaaaaa gtcaggcagg tttcatctta
    46621 gtagaacagc cattctgaaa aatgttggtg ctcaatacat tggtttaaaa gaggatgaaa
    46681 gcgatcaaag aatcatcctg atgctttcag gaggcttgat ggttcatctc ggcttgatat
    46741 tattggcgat attgtttgga tttttgacaa gaagctggta ttttgcaggg acttggattt
    46801 ttcttaattt atctttcttc ctaaataaca ttttgccagt cgacatcacc gatggagcaa
    46861 aaatttggga attactacaa caccctgaaa ataccaaata cgcctacctg gtattgagac
    46921 attctgccca gaccttgcta gctcctcaag aatatgattt gaaagacttt gttcaagcag
    46981 ttcctgagga tgcacgaggg agttttgcgg atggtgtatt aggtatgcaa ggtgaagttt
    47041 ccattttgga agggaaggaa gaagtagcta aacagcagtt tcaagcatta cttgagagga
    47101 caactactcc gatgatgcag acagttgccc aactatccct gcttcatatc gccttgttgg
    47161 aaggagattt tgagcaagcg gagcaatatg ctagtattcg acaggtcaaa tcgtttctgt
    47221 ctctcaaact gtccaatctt caagtgatac aagcctggta tcaattaaag gtgaagaaag
    47281 atgtagatcg aactcgtaag gctctcaaga ttgctagaca gaaaatggat agtagtcgaa
    47341 tgttgaggga tgagaaaaga tattatgaaa actggttagc cgagctggaa aaggaaatgt
    47401 tagaaggaac tgaagatgga actagaaatt tctgatttca caggttgcaa gattgctttg
    47461 ttttgtgggg ataagctttt gactatctta cgcgatgata aggcaagtat tccctgggcc
    47521 aatatgtggg aactgccagg tggtggacgt gaaggtgatg aaagtccttt tgagtgtgta
    47581 gcgcgtgaag tttatgaaga actgggcatt catctgactg aagattgtct gctttggagt
    47641 aaggtttacc caagtatgct ttttgcagac aaacagtccg tttttctagt tggtcagttg
    47701 acacagaacc agtttgacag tatcgtattt ggagatgaag gacagggcta tcagctgatg
    47761 aatgttgagg aatttcttag ttccagtcaa gttgtgcctc agttgcaaga gagattaaaa
    47821 gattatttaa aagtaagtga ttagaaagga tggttcggtt aaatttctaa actgaacccg
    47881 ccctaaacac ggtgccaaaa agataaactt ctcttagaca caagcgtctt cagagaattt
    47941 cctattttgg ttttgtgttt tacgggcttg gtattaataa tggaaacatg gcaagagtta
    48001 aaagttacag tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga
    48061 gcgcaaggag tcgcaatcga agacagtatg gactatgtgg gaaatgtgga ccgctttgga
    48121 gagattttcc cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac
    48181 acggtggatg tgacagtggt tgaggcggat ttgcaggctc gtctagcaga attgacagat
    48241 tttatggatt tgggagagtt aaaaataggt acgactgcct tggctgagga agactgggca
    48301 gacaactgga agaaatacta tgaacctgct cgcatcactc atgatttgac catcgttccc
    48361 tcttggacag actatgaggc gactgcggga gaaaaaatta tcaagctgga tcctggcatg
    48421 gcttttggta cgggaaccca cccaactacc aagatgagcc tttttgcctt ggaacaggtt
    48481 cttcgtggtg gcgaaacggt gctagatgtg ggaactggtt caggggttct ctctattgcc
    48541 agctcgcttc tgggggctaa agaaattttc gcctatgacc tggatgatgt ggcagttcgt
    48601 gtggctcagg aaaatattga gctcaaccct ggaatggaaa atatccatgt agcggcaggc
    48661 gatttgctta aaggcgtgga gattgaagca gatgtcatcg tggcaaacat cttggcggat
    48721 atcctcattc atctgacaga ggatgcttat cgcttggtta aggatgaagg ttacctgatc
    48781 atgagtggca ttatcaagga taagtgggac atggtgcgcg agttggctga atcagctgga
    48841 tttttcctcg aaactcacat ggttcaaggg gaatggaatg cctgtgtctt taagaaaacc
    48901 aaggatatct ctggtgtgat tggaggctag catgcagcag tattttgtaa aaggcagtgc
    48961 tatctctcct gtcactatcg agaacaagga aaccagtaag catatgtttc aggttatgcg
    49021 cttgaaagaa gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg
    49081 cgtgctggat atggaaaatc gtcagtttga gttggtccaa gaattaaatg acaatgtgga
    49141 actaccagtc caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat
    49201 cgctcaaaaa gtaaccgaac tgggtgctag ccaaatctgg gcctttcctg cagactggtc
    49261 agttgccaag tgggatggca agaaattggg taaaaaagtt gaaaaactag aaaaaattgc
    49321 ccttggagca gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa
    49381 aaaagcagat tttctagctc agctggacca gtttgactct atcatagtag cctatgaaga
    49441 atcagctaaa gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg
    49501 agccaaactg ctctttatct ttggtccaga aggcggtctg tcacctgcag aaatcgaaag
    49561 ttttgaagct aagggagccg ttttggtagg cctaggtcct cgtattttgc gagcagaaac
    49621 agcaccgctt tacgccttat cagcccttag tgttttagta gaattagaga aataagagga
    49681 agaaaatgga acaaaaacac cgttcagaat ttccagagaa ggaactctgg gacttaacag
    49741 ccctatacca agaccgtgag gatttcttgc gtgcaatcga gaaagctcgc gaagacatca
    49801 accagtttag ccgtgattac aagggcaatc ttcacacttt tgagaatttc gagaaggcct
    49861 ttgcggaatt ggaacagatc tacattcaga tgagccatat tggcaactat gcttttatgc
    49921 ctcagacgac ggactatagc aatgacgaat ttgccaatat tgcccaagct gggatggaat
    49981 ttgaaacaga tgccagcgta gccttgacct tctttgacga tgccttggtg gtagcagacg
    50041 aggaagtctt ggaccgtttg ggtgaattgc ctcacttgac ggcagctatt cgtcaggcca
    50101 aaatcaaaaa agcccactat ctaggggctg atgtggagaa ggccttgacc aatctcggtg
    50161 aagttttcta tagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg
    50221 ctgactttga agcccatggc aagacctaca aaaacagctt tgtcacctat gagaatttct
    50281 accaaaatca cgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac
    50341 ttcgtaagca ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac
    50401 tcttggctga tatgaaggga tatgactctg tctttgatta tcttctagct gaacaagaag
    50461 tggaccgtgt catgtttgat cgccagattg acctcatcat gaaggacttt gcaccagtcg
    50521 ctcagagata cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag
    50581 actggaaatt ggacttggac agcgccctga atcctgaagt gactattgac gatgcctatg
    50641 atttggtcat gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt
    50701 accaagaaga gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg
    50761 cggcggaccc atatcgcgta cacccttatg tcctcatgag ctggacaggc cgtttgagcg
    50821 atgtctatac cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc
    50881 atcaaagtta cttcaatgcc catatgtcga cctactatgt tgaagcaccg tcaaccttca
    50941 atgaattgct actcagtgat tacttagaga accaatctaa tgacccacgt caaaaacgct
    51001 tcgctctggc tcatcgcttg acagacacct acttccataa ctttatcacc cacctcttgg
    51061 aagcagcctt ccagcgtaag gtgtatacat tgattgaaga aggagaaacc ttcggagcaa
    51121 gcaaactcaa cagtattatg aaggaagttt tgacagattt ttggggcgat gccattgaaa
    51181 tcgacgacga tgcagctttg acttggatgc gccaagctca ctactatatg ggcttgtata
    51241 gttacactta ctcagcagga ctagttatct cgactgctgg ttaccttcat ctaaaacatt
    51301 ctgaaactgg agctgaagac tggctcaatc tccttaaatc aggtggtagc aagacaccac
    51361 ttgagtcagc catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca
    51421 tccaattctt gtctgacaca gttgaccaga ttatcgccta cagtgctgag ttgggggagt
    51481 aaggggatag agaggttgtt atagaatggg tatggacagt tatttgctta aaattccatg
    51541 tttaaatccc ccattccttt tcgaggaatt ctttgccctt ctctgtaatg gtaagtgaac
    51601 gtggcgtttg tgcagggatg accaattgtt tttcactgaa aaattctaaa agagcattgc
    51661 cgagagctcc gccgacatga tttttacgtt cgctccaatc caaacattta gggcaaaatt
    51721 tccgtttttt ctttttcaat tcatccgtat caatgtgtaa ttttctttgg aaataagact
    51781 tcccagcttc agtgagttgg aagtcttttt ctgattcgct gaggagattt tcttgcaaga
    51841 gataattggt aatggaaatg ccaagctcac cagcaatatg gtcatagcag gtgcgagcga
    51901 cttttaattc ctttttgtga atgtgttgtt tataactttt gacatcacgc tgaggagagt
    51961 agaagctgag aaattccagc atttctgcaa tggcagcact ttttaaagaa taataatgaa
    52021 aacgtccata ggtttgtaga gtggttacct gcgcttcggt aagtaatttg aggtgatagc
    52081 tgacagtatg ttgcttgatt ttggtaaagc tggcaatttc gttaaccgtg tgagcttttc
    52141 catccattag aatatctaaa atgtgcatcc gagaagggtc tgataagagt tttgtgatga
    52201 tgaaaatatc tggttccata aaaattttct ccaaatttca tatatcgatg attttctatc
    52261 ttttattata ctataattaa agcacaagaa aaatagattt taaaaatgtt ttactagaga
    52321 atattttaaa ttttattgtc tgagtttaaa tggaggtaaa attacaaaag taattgcagc
    52381 agtatccaca gttgagggac gttaatctta agattaacgt ccctcaacat tttttcaaaa
    52441 gtgagatgaa ttaacaaagt atccaacatg ctctatttgt gggggaaaga aagagtgaag
    52501 aagttaagtg ttaaaaatct aaaaaagcaa tatggttctt atgaagctgt caagggaatt
    52561 agctttgaat tgggagaagg agagtgtttg ggtatcttgg gaatcaacgg tgctggcaaa
    52621 acatccactt taaagatgat ttactcactg acctcaattt cctcaggaga gattgatatc
    52681 ttggggcaaa atattgaaac caatcgtcgt aagagtaaat cttgtctggg tattgtaggg
    52741 caggaggata tgctggacat gaccttgaat gtttatgata atctttttgc tcacggtcta
    52801 tgctatggta tctcatctgt cgaacttagg aagagaatcg attctctctt ggattttgtt
    52861 caactgagca aacatgcgca aaagatggtg aatcagctgt cgggtgggat gcgacgacgt
    52921 cttgtcttgg caagagctct catcaatcgg cctgatatta tcattttaga tgaaccgaca
    52981 gttggtttag acattcaatc ccgcaatatt atttgggata aacttttgga gttgaaggaa
    53041 ttaggtgttt ccatcattat tacttcccac tatatgaatg agattgaata tttgacagat
    53101 agggtgctga tgctccacca agggactatc aaagaagaag gaactgtaga agacttgctc
    53161 atcaagtatg atgctgacaa ccttgagacg ctttttttgg ggttgactgg gacagagaag
    53221 gaggacttgc atgtttaagt tatcatttca ctccatcgga cacgttgtgg tacgcaacta
    53281 catgagtttt agaaatttat ttaaaatttc aattgttccc aaccttatcg accccctctt
    53341 ttatctttta gcaatgggat ttggagttgg tgcctatttg acgcatgtta acggtatgct
    53401 ctaccgtgat tttgtcatta caggtttaat tgctgcgact gctatgtctg cggccaccgc
    53461 agaaacaacg gtcaatgcct ttatccagta taagattgaa aagacttatg atgctatatt
    53521 gatgacgcca atcaatacga gtgatattgt ggtgggtcag gctatctggg caggtattcg
    53581 tgcagtgatt ttcggtggga ttttttggct gatttctatg cttatcacag cgcattttca
    53641 tgtcttgatg ttattgattc ctctgatttt atttatagtg ggttatttgt ttggtgtttt
    53701 gggactaatc tttacctact tggcgccgtc tagggaattt ctgaattact acaatgtttt
    53761 ggtaatccgt cctctttata tgttttcaga taccttcttt cccattactt ccttgccccc
    53821 aatacttggt gatttgactt ggttttctcc cttgtatcat gctactcgca tgattcgtat
    53881 tatatgggga ggtgaggtga caggtttgta tcttcatctt atctggttga tagccttggc
    53941 gctcttgata acggtgcttc ctatgtatat gttacatcgt agatattata gatagtctaa
    54001 ttatttgtga tgttgtagtc atattctaat ttatactaaa cgttattcga atttgggcag
    54061 gtatgggaac tgtgcctatc aatattgtaa tttatggaag ttgaaatagt acggttcagt
    54121 ttttaaaata ttgttagaaa ttgttttaaa ttccctaatc aatttgtata gtttttattt
    54181 cactttatta taactagttt ttcgcaattt ttgagacagg aatgtgattt ttgtgataag
    54241 gctctatcat tacaagttta tttgttgtaa tatggaataa atcatttata tatcttttca
    54301 gaaatatgct gtttctctga ctataaatgt ctttttcttt ttaacttaat tttacaaatt
    54361 ggtaaggtca tttaagactg cttttttgaa cagttgctag aaatgtagag gtattgacca
    54421 tgtatcaaga tttactaaga aaaatagcag aagaaaaacc aaattataac caggaggaaa
    54481 tccagtggtt gcttgatcat ttgggagatc cttctccaga aattcgcgat gaccttgttt
    54541 ttacaagctt tgctagaggg attcaggaag agctatttac acaggagcaa tttcatttca
    54601 ttgctgaagg ggtttcatct gatgtaggac tagataaaga gattgataag gtaggtctgc
    54661 caacacttga acgttctttt agggcacttg tttatgcaaa tctcttgtat gcagatgcca
    54721 accagcaatc ggttttttat cagggattac aattagaaat tcgtaatgtc ttttcaaatc
    54781 aaggcttgca ctatctttca aaagaaaagg atacaacagg tttctcaagt cagtatggtt
    54841 ggattcattc ttttgcacat ggagccgatt tactgacaga ggtggtctgt catccagact
    54901 ttcctataaa cagaattcat gaagtatttg acatacttgg ccaactattt aaaagaatgt
    54961 cgattcgctt tacagatgat gaggattggc gtttagcaag agtgatctat gaacctattt
    55021 tacaagggaa gttggagcaa gaacaagtag cttcttggat aaaaactgtt gattttccga
    55081 tagaagaaag ggaggatttt tacaaatttt ccaactttag atcctgtctg gtggaagtct
    55141 atgtccaact tgaccagaga aatagtttac aagatgacct gaaagaagct atccagtctt
    55201 ttcaatacta gggattagct aatagttcta tgattttcaa aaaatttcca atcaattttc
    55261 ttgaaaccct ttcctacttt tgatagacta gtatctagtt tttgaaaaaa ggagaaagaa
    55321 aatgaaaaaa tttgttgctg agttaatcgg tacgttcatg cttgtgttcg ttgggacagg
    55381 agctgttgtt tttggaaatg gttttgatgg ccttggtcac cttggaatcg cctttgcctt
    55441 tggtttggca atcgtggtgg cagcctactc aatcggaact gtttcaggtg ctcacttgaa
    55501 cccggctgtt tcgattgcta tgtttgtaaa caaacgtttg tcatcttcag aacttgtaaa
    55561 ctacatcctt ggtcaggttg ttggagcttt catcgcttct ggcgcagtct tcttcctctt
    55621 gggtaattca ggtatgtcaa ctgctagcct tggtgaaaat gccttggcaa acggtgtcac
    55681 tgtctttggt ggtttcttgt ttgaagtcat cgcaactttc ttgtttgtct tggttatcat
    55741 gactgtgact tcagaaagca agggcaatgg cgcgattgct ggtttggtaa tcggtttgtc
    55801 attgatggcg atgattcttg tcggattgaa gattactgga ctttcagtaa acccagctcg
    55861 tagcttggca ccagctgtct tggtaggcgg cgcagccctt caacaagttt ggattttcat
    55921 ccttgcacca atcgctggtg gagttcttgc agcccttgtt gcaaaaaatt tccttggaac
    55981 agaagaataa ttgaaactca aaaagccttg ctcctcatct tgaggaacag ggctttttcg
    56041 tatgatactc ttc
//
LOCUS       DBEJZJ010000011        55320 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000011 DBEJZJ010000000
VERSION     DBEJZJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 55320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.11"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            116..838
                     /locus_tag="ACL3R8_000840"
     CDS             116..838
                     /locus_tag="ACL3R8_000840"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR1313746.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1055..2389
                     /gene="pepC"
                     /locus_tag="ACL3R8_000841"
     CDS             1055..2389
                     /gene="pepC"
                     /locus_tag="ACL3R8_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR1313747.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2445..3356)
                     /locus_tag="ACL3R8_000842"
     CDS             complement(2445..3356)
                     /locus_tag="ACL3R8_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1313748.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3380..4183)
                     /locus_tag="ACL3R8_000843"
     CDS             complement(3380..4183)
                     /locus_tag="ACL3R8_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR1313749.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4211..5200)
                     /locus_tag="ACL3R8_000844"
     CDS             complement(4211..5200)
                     /locus_tag="ACL3R8_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1313750.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5433..6452)
                     /gene="adhP"
                     /locus_tag="ACL3R8_000845"
     CDS             complement(5433..6452)
                     /gene="adhP"
                     /locus_tag="ACL3R8_000845"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR1313751.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(6791..7603)
                     /locus_tag="ACL3R8_000846"
     CDS             complement(6791..7603)
                     /locus_tag="ACL3R8_000846"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1313752.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7793..9211
                     /locus_tag="ACL3R8_000847"
     CDS             7793..9211
                     /locus_tag="ACL3R8_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR1313753.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9264..9971
                     /locus_tag="ACL3R8_000848"
     CDS             9264..9971
                     /locus_tag="ACL3R8_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1313754.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            10066..11040
                     /gene="folP"
                     /locus_tag="ACL3R8_000849"
     CDS             10066..11040
                     /gene="folP"
                     /locus_tag="ACL3R8_000849"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR1313755.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            11042..12364
                     /locus_tag="ACL3R8_000850"
     CDS             11042..12364
                     /locus_tag="ACL3R8_000850"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR1313756.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHFKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            12345..12899
                     /gene="folE"
                     /locus_tag="ACL3R8_000851"
     CDS             12345..12899
                     /gene="folE"
                     /locus_tag="ACL3R8_000851"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR1313757.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12942..13754
                     /gene="folK"
                     /locus_tag="ACL3R8_000852"
     CDS             12942..13754
                     /gene="folK"
                     /locus_tag="ACL3R8_000852"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR1313758.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(13799..14116)
                     /locus_tag="ACL3R8_000853"
     CDS             complement(13799..14116)
                     /locus_tag="ACL3R8_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR1313759.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
     gene            14473..14919
                     /gene="rplM"
                     /locus_tag="ACL3R8_000854"
     CDS             14473..14919
                     /gene="rplM"
                     /locus_tag="ACL3R8_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR1313760.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14939..15331
                     /gene="rpsI"
                     /locus_tag="ACL3R8_000855"
     CDS             14939..15331
                     /gene="rpsI"
                     /locus_tag="ACL3R8_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR1313761.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            15680..15889
                     /locus_tag="ACL3R8_000856"
                     /pseudo
     CDS             15680..15889
                     /locus_tag="ACL3R8_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16045..16383
                     /locus_tag="ACL3R8_000857"
     CDS             16045..16383
                     /locus_tag="ACL3R8_000857"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGR1313762.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            16573..18009
                     /locus_tag="ACL3R8_000858"
     CDS             16573..18009
                     /locus_tag="ACL3R8_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR1313763.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            18061..18300
                     /locus_tag="ACL3R8_000859"
     CDS             18061..18300
                     /locus_tag="ACL3R8_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGR1313764.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            18430..18744
                     /locus_tag="ACL3R8_000860"
     CDS             18430..18744
                     /locus_tag="ACL3R8_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGR1313765.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIATAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            18862..20841
                     /locus_tag="ACL3R8_000861"
     CDS             18862..20841
                     /locus_tag="ACL3R8_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR1313766.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            20851..21165
                     /locus_tag="ACL3R8_000862"
     CDS             20851..21165
                     /locus_tag="ACL3R8_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGR1313767.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            21196..21702
                     /locus_tag="ACL3R8_000863"
     CDS             21196..21702
                     /locus_tag="ACL3R8_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313768.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            21782..23128
                     /gene="celB"
                     /locus_tag="ACL3R8_000864"
     CDS             21782..23128
                     /gene="celB"
                     /locus_tag="ACL3R8_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGR1313769.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            23508..23684
                     /locus_tag="ACL3R8_000865"
     CDS             23508..23684
                     /locus_tag="ACL3R8_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313770.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            24094..26307
                     /locus_tag="ACL3R8_000866"
     CDS             24094..26307
                     /locus_tag="ACL3R8_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR1313771.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(26529..27005)
                     /locus_tag="ACL3R8_000867"
     CDS             complement(26529..27005)
                     /locus_tag="ACL3R8_000867"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR1313772.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            27228..30428
                     /locus_tag="ACL3R8_000868"
     CDS             27228..30428
                     /locus_tag="ACL3R8_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR1313773.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            30808..31184
                     /gene="tnpA"
                     /locus_tag="ACL3R8_000869"
                     /pseudo
     CDS             30808..31184
                     /gene="tnpA"
                     /locus_tag="ACL3R8_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            31366..31428
                     /locus_tag="ACL3R8_000870"
                     /pseudo
     CDS             31366..31428
                     /locus_tag="ACL3R8_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(31572..32201)
                     /locus_tag="ACL3R8_000871"
     CDS             complement(31572..32201)
                     /locus_tag="ACL3R8_000871"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGR1313774.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(32211..33212)
                     /locus_tag="ACL3R8_000872"
     CDS             complement(32211..33212)
                     /locus_tag="ACL3R8_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR1313775.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(33243..33884)
                     /locus_tag="ACL3R8_000873"
     CDS             complement(33243..33884)
                     /locus_tag="ACL3R8_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR1313776.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(33903..34718)
                     /locus_tag="ACL3R8_000874"
     CDS             complement(33903..34718)
                     /locus_tag="ACL3R8_000874"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR1313777.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            34989..35417
                     /locus_tag="ACL3R8_000875"
     CDS             34989..35417
                     /locus_tag="ACL3R8_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIA"
                     /protein_id="HGR1313778.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            35429..36619
                     /locus_tag="ACL3R8_000876"
     CDS             35429..36619
                     /locus_tag="ACL3R8_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR1313779.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            36630..37121
                     /locus_tag="ACL3R8_000877"
     CDS             36630..37121
                     /locus_tag="ACL3R8_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1313780.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            37136..37915
                     /locus_tag="ACL3R8_000878"
     CDS             37136..37915
                     /locus_tag="ACL3R8_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR1313781.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            37902..38720
                     /locus_tag="ACL3R8_000879"
     CDS             37902..38720
                     /locus_tag="ACL3R8_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1313782.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            38720..39013
                     /gene="yajC"
                     /locus_tag="ACL3R8_000880"
     CDS             38720..39013
                     /gene="yajC"
                     /locus_tag="ACL3R8_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR1313783.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            39035..40936
                     /locus_tag="ACL3R8_000881"
     CDS             39035..40936
                     /locus_tag="ACL3R8_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR1313784.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            40996..41997
                     /locus_tag="ACL3R8_000882"
     CDS             40996..41997
                     /locus_tag="ACL3R8_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1313785.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(42107..42442)
                     /locus_tag="ACL3R8_000883"
     CDS             complement(42107..42442)
                     /locus_tag="ACL3R8_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313786.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(42453..42695)
                     /locus_tag="ACL3R8_000884"
     CDS             complement(42453..42695)
                     /locus_tag="ACL3R8_000884"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313787.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(42706..43248)
                     /locus_tag="ACL3R8_000885"
     CDS             complement(42706..43248)
                     /locus_tag="ACL3R8_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGR1313788.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(43264..43458)
                     /locus_tag="ACL3R8_000886"
     CDS             complement(43264..43458)
                     /locus_tag="ACL3R8_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1313789.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            43624..44574
                     /gene="rsmH"
                     /locus_tag="ACL3R8_000887"
     CDS             43624..44574
                     /gene="rsmH"
                     /locus_tag="ACL3R8_000887"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR1313790.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            44586..44903
                     /gene="ftsL"
                     /locus_tag="ACL3R8_000888"
     CDS             44586..44903
                     /gene="ftsL"
                     /locus_tag="ACL3R8_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR1313791.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            44907..47159
                     /gene="pbp2X"
                     /locus_tag="ACL3R8_000889"
                     /gene_synonym="pbpX"
     CDS             44907..47159
                     /gene="pbp2X"
                     /locus_tag="ACL3R8_000889"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR1313792.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            47161..48141
                     /gene="mraY"
                     /locus_tag="ACL3R8_000890"
     CDS             47161..48141
                     /gene="mraY"
                     /locus_tag="ACL3R8_000890"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR1313793.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            48750..50855
                     /locus_tag="ACL3R8_000891"
     CDS             48750..50855
                     /locus_tag="ACL3R8_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1313794.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(51151..51633)
                     /locus_tag="ACL3R8_000892"
     CDS             complement(51151..51633)
                     /locus_tag="ACL3R8_000892"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR1313795.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(51728..53212)
                     /locus_tag="ACL3R8_000893"
     CDS             complement(51728..53212)
                     /locus_tag="ACL3R8_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR1313796.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            53365..54972
                     /locus_tag="ACL3R8_000894"
     CDS             53365..54972
                     /locus_tag="ACL3R8_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR1313797.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENSNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            55131..55304
                     /locus_tag="ACL3R8_000895"
     CDS             55131..55304
                     /locus_tag="ACL3R8_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR1313798.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
BASE COUNT        16964 a         9754 c        12122 g        16480 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgc ggtttgaaga gatttttgaa gagtatgaaa
       61 cgaaaaggag gttggtcatt gtactagcct ccttttgata tgatataata gttctatgag
      121 attagataaa tttttagttg cctgtgcggt gggaagtcgg actgaggtca aaaacttgct
      181 caaggctggg cgcgtgactg taaatggtaa aaaagaaaaa tcagctaaat tgcagattga
      241 tgaaaaaata gatgagattc gctttgatgg gcaagtgttg gagtatgaag agtttgtcta
      301 ctacatgatg aacaagccca aaggagttat ctcagcgact gaggatccca agcacagaac
      361 cgttctggac ttgttggatg acttggcgcg gagtaaggaa gtttttccag taggacgctt
      421 ggatattgac acgcatggtc ttttgctctt gaccaataat ggtcagctgg ctcatgttct
      481 tctttcgccc aagcgtcatg tggacaagac ttatcaggct caggtcaagg gaattatgac
      541 ccaagaagat gtggagacat ttatcaaggg cattccgctc aaagacttta cctgtcagcc
      601 cgctagactg gagattcttt ccacagatgc agaaaagaat cagagccaaa tccgtgtgac
      661 cattgcagaa gggaagtttc atcagatcaa gcgtatggtg ggctactgtg gcaaggaagt
      721 ggtggacttg caacgattga ctatgggaac tttagtatta gatgagaacc tggaacgagg
      781 ggaatggcgt cgcttgacca aggaagaatt agaaattctc cgcgctaata ttatttaatt
      841 tagtttaata ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgtactt
      901 gagtacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta taaattcgaa
      961 aaaggtgagg gacaatgtcc tcgcctttta tgttttttag ttgcttcctt tgtgaaaaga
     1021 gttataatag actgtagaat aaaaggagga atctatgaac gcgattcaag aatcatttac
     1081 tgataaacta tttgccaact atgaagcaaa tgtaaaatac caagcgattg aaaatgctgc
     1141 cagccacaac ggaatttttg cagctctgga atgtcgccaa agccatgtag acaacacacc
     1201 tgttttctca ttggatttaa ccaaggacaa ggtcactaac cagaaagcgt ctggtcgttg
     1261 ctggatgttt gcggctctca acaccttccg ccacaaactc atctcgcaat acaaattgga
     1321 gaactttgag ttgtcacaag cccacacttt cttctgggat aagtatgaga aatcaaactg
     1381 gttcttggag caagtcattg cgacttcaga ccaagaattg actagccgca aggttagctt
     1441 cttactccaa acacctcaac aagatggcgg tcaatgggat atggtcgttt ccctctttga
     1501 aaaatacggt gtcgtgccta agtcagttta tcctgagtct gtttcatcta gcagcagtcg
     1561 tgagctaaat gcgatcctta ataaattgct tcgtcaagat gctcaaatct tgcgtgattt
     1621 gcttgtttct ggtgcagatc aagcgactgt tcaagctaag aaagaagacc tcttgcaaga
     1681 aatctttaac tttcttgcta tgtcattagg acttccacca cgcaagtttg actttgctta
     1741 tcgcgataaa gataacaact ataaaagtga aaaaggaatc acaccacaag agttttacaa
     1801 gaaatatgtc aatcttcctt tagaagacta cgtttctgtt atcaatgctc caactgctga
     1861 taaaccttac ggaaaatctt acacagttga gatgttgggg aatgtggttg gtagccgtgc
     1921 agttcgctac atcaacgttc caatggagcg cttgaaagaa ttggcgattg cccaaatgca
     1981 agcaggtgag actgtttggt ttggttctga tgtcggccag ctcagcaacc gtaaggctgg
     2041 catccttgcg acagatgttt atgactttga atcaagcatg gacattaaac ttactcaaga
     2101 caaggctgga cgtttggact atagcgaaag cttgatgacc cacgccatgg tcttgacagg
     2161 tgttgacttg gacgaaaatg gtaaatcaac caagtggaag gttgaaaact catggggaga
     2221 caaggtcggt acagatggtt actttgttgc ctcagacgct tggatggacg aatacacata
     2281 ccaaatcgtt gttcgtaagg aattgctgac agcagaagaa caagctgcct atggagcaga
     2341 accaatcgta cttgcaccat gggatccaat gggagccttg gctgaataaa agcatagaaa
     2401 aaaggaatca gattttagaa cctggttcct ttttagttgc ttgattacat gatgtgaaga
     2461 acatgtgcca caatacccac tgcgaagagg gcaaggataa tagtgattgg agatactttt
     2521 ttcttaagta agtacatgca aagtaaagta aggagtagtc ctgataatcc aggaatcaac
     2581 atatccaagt tttgttggaa agtagtaact ttttcaggag tttgagacaa tccttgtcct
     2641 acttgtgcga atgcttcttg gataccttta gacccttctg gcaatttatc ccaatggata
     2701 taagcctttt catctagttg aactttagaa acatcgaaag caaatttaat atttacccag
     2761 cgttgaacaa ggacagcaag aatgaacatc ccaaggatag aagctccttt agtgatatct
     2821 tgaaggatac caccagacat atctttagtg atttctgatc cagccttgta tccaatctct
     2881 tgaacatacc acaagaatga catacgaatc aagttccatg caacaaagaa gaggagtggc
     2941 cccaagatat tgccagtaag ggcaagtgaa gcaccgagag atccaaggat tgggcgtact
     3001 gtaaaccaga atactgggtc accgatacca gcaagaggtc ccatcatacc gattttaacc
     3061 ccttggatag cagcgtcatc gatttccaca ccgttagcac gttcttcttc aagcgcaaga
     3121 gtaaccccca tgactggagc agctacgtat ggatgagtgt tgaagaactc aaggtgacgc
     3181 tcaagagcag cgatttgatc ttctttttta gtatagagtt ttttgatagc tggaatgagt
     3241 gtataagccc agcccaagtt ttgcatccgt tcaaagttcc aagacccttg taagaaggtt
     3301 gaacgccacc aaactttttt acgatctgat ttagttaatt gaagtttttc agtcatgatg
     3361 ttttcagtcc tttcttatct tagtagtctt ctaggatatc gccgattggg tcgttagaag
     3421 ttgcggctcc tccgccacca tttccaccag ttttagaaag gtgaaggtag ataagagcga
     3481 tagcaacacc gatagcaccg aatccgatta gagtaatatc tgacacagca gcaagaacga
     3541 aaccaagagc gaagaatggc catacttcac gagttgccat catgttgata accatggcgt
     3601 aaccaacggc aacgaccata ccaccaccga tagccatacc atctttgagc cagtctggca
     3661 tggcactaag gatactttgt acagtttcag ttggtaccat aaggagaaga gctgcaggaa
     3721 gcgcgatacg aagtccttgg aaaagtagcg caatgaaatg agcacgctcc acagcgccga
     3781 agtcaccttt tttagcggca gcatcagcag tgtgaaccaa tccaactgaa attgtacgaa
     3841 caatcatagt taagaataga ccagctacgg caagagggat agcaaccgct tgggcaacac
     3901 cgataccagt cttggtaaag tcaccaccaa gaaccatgat aatggcagca gcgacagaag
     3961 caagtgcagc atcaggagcg atagcagcac cgatatttga ccaaccaagg gcaatcattt
     4021 gaagcgatcc accgaggata atccctgctt ccaagtgacc tgttacaagc ccaataaggg
     4081 tacaggctac aagtggttgg tgaaattgga actggtcgag gatgccttca agacctgcaa
     4141 agaaggctac aacgactact aaaaccatag aaataataga catgtttaaa atcctttcat
     4201 aaataatggc ttatttgaca ttggctttgt taatcaagtc aaacaaatct tttttagaat
     4261 catttggtac tttacggaca tcaaattcaa cacccaagtc acgcattttt tcaaatgtag
     4321 caacatcttc tttgtccata gacaaaacgg tattgaccaa tgttttacct gttgagtgag
     4381 ccatagaacc aacgttaaga gtcttgattg gcacgccgcc ttcgatggca cgaagggcat
     4441 cttgaggtgt ttcaaacaag ataagggcat gtgtttctcc aaaacgtggg tcttttgaaa
     4501 tctcaatcag tttttgaatt ggaaccacgt tagccttgac attacctgga gctgcttgtt
     4561 taatcaattc tttacgaagg tcgtctttag ccacgttatc tgaagcaacg atgatacgat
     4621 ttgcttttga atctggagtc caagcagttg caacctgacc gtgaagtaga cgtgtgtcaa
     4681 gacgggcaag attgattttc aatttaccgt ctccgataac agttccttct gggatagcag
     4741 tttgggcaac tggagcagct gcagcgcttg caacttcttc aactggattt agctcttctg
     4801 gaagagcttt gatgccatct ttggcttctt taatgatatt agcagcgact ttttctacac
     4861 ctgcagcagc gtccatgagg cgctctgtgt aggcttgaat caacatcggt aagttaagtc
     4921 ctgtgatgat ggcaaactta cgctcaggat tttctcccat cacgcgacta gcttggttaa
     4981 atggagaacc actccaaagg tcagccaaaa ctagaacctc atcttctgcg tcaaatgcag
     5041 caacagcgtt attaaactta gcgtatagat catcaggacc ttcatttggc ataaaggtca
     5101 caacttgaac cttttcttgt tcaccaaaga tcatagatcc tgactgatga atacccgcag
     5161 caaattcgcc gtggctcgca ataatgattc cgatactcat tattgtcatt cctccttttt
     5221 tgttttagtt ttcatttaag aaaactttaa gactgtttaa gtataaaccg ttttcataaa
     5281 aaaagcaact atttatcata aaaaattaaa aaatttttat ttttgtatgt tgatatgttg
     5341 agtttttgag gagtaatctt gaattcttat ttaaaattta atataaaaaa gttggaagaa
     5401 gcttccaact tttaaaatag gtttctatta aattagtggg tgaagtcgag taccatacgt
     5461 ccttggattt ggcctttttc catttcgtcg aaaatggcaa cagcatcttc tactggacgt
     5521 ttttgaacaa ctgggactac cagaccttct gcaccaaatt ggaaggcttc ttctaagtct
     5581 ttacgagttc cgacaagaga accgatgact tggattccat cgaggactgt tttaacgatg
     5641 ctgagttcca tcatttcaga aggaagacca acagcgacga cgcgaccacc agcacgaatg
     5701 gagtcaacag cctggttgaa ggcaacttta gacacagcag ttacgacagc tgaatgagct
     5761 cctccatcag ttttttcttt aatgagtcca gctacatctt caacttcgag gccgttaatc
     5821 acaatgtcag cgcctacttc ttttgcaagg gtaagtttgt cattgttgat atcgactgcg
     5881 ataacatgag cattgaatac ttttttagcg tattgaacag cgaggttacc aagtccacca
     5941 gcaccgtaaa gaacaaccca ttggcctggt tcaacttttg cttctttgat agctttatag
     6001 gttgttactc cagcacatgt gatagaagaa gcttgggctg gatcaagtcc gtcaggaact
     6061 ttgacagcat agtcagcagt tacgatacat tgttcagcca taccaccgtc tactgagtag
     6121 ccagcatttt tcactgtacg gcaaagggtt tcgcgaccag ttgtacagta ttcgcaagtg
     6181 ccacatcctt caaagaacca agcaacgctg acgcggtcac cgactttaag gcttttcaca
     6241 tctggagcaa tctctttaac gataccgata ccttcgtgcc caagaacacg tcctgggact
     6301 tgaccaaagt caccatgagc aacgtggagg tcggtgtggc aaacgccaca gtattcaact
     6361 tctacaagtg cttccccagt ttcaagtgga cggagtactt tttcttcaat agcaacacca
     6421 gtgctttctg gatttacaac aacagctttc atagctatcc tccttgatat tgaccgagaa
     6481 cagggacaac gggactggat tgattttttg tcaacagagt cgagtgtgac gagctctctt
     6541 gtatttatat gtgaagtata tcacaaaagg aagccttttc caaggttttg gagacaaaaa
     6601 gtagaacaat cgattaactg gttgatgaga ctgtgaaaag agcacaaaga ccagcttgca
     6661 agctggtcat actcttcgaa aatctcttca aaccacgtca gcttcatcta caacctcaaa
     6721 gcagtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattc tcattgagta
     6781 tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct tggtcgttgg
     6841 taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt ttcatggcat
     6901 aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca aaggcaatca
     6961 aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag gccttgttga
     7021 caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg atagaaagtt
     7081 gatgctggta gaaggcgttc atttcttttg ccaaggcata tttgtcactg gctctggtct
     7141 gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga tcttcaggct
     7201 ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga tttgtaatgt
     7261 agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct gaacgttgaa
     7321 ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc caaacttggt
     7381 ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag cccagttcac
     7441 ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc tgatggcctt
     7501 tttcagcaac ttttttgatg gttcttttgg taaagtcaga aatttgactg tctgagttga
     7561 gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc tttctagtgt
     7621 gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca gattccaaac
     7681 aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga aaaagtgaat
     7741 gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga tgatggacaa
     7801 attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg ctggtttaac
     7861 aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt cacaaacagg
     7921 aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg gtaccttgat
     7981 gatggctttt tatgctaact taccttatgc ccaagcacca ggtatgggac tcaatgcctt
     8041 ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc tagctatggt
     8101 cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta aaatgatcat
     8161 tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg tcttccttgc
     8221 ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag gcaactatac
     8281 tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact cttcagcagt
     8341 tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag gacttgccat
     8401 tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta tcttgacaac
     8461 aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt ttgctaataa
     8521 ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc ttggttcaga
     8581 aggtttggga gctttggttt cagatacagc tcgcttgcct gaaactctga tggccattct
     8641 tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta caggtgaaaa
     8701 agttggtatt gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg ataaggctct
     8761 ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa acgtaacgac
     8821 ttatgttgag tctgctgctg gtatcggtgc aggtggacgt actggtttga cagccttggt
     8881 tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga tcgtaccaac
     8941 agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta gcttgaaaaa
     9001 tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta tctttatggg
     9061 attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca ctttgactaa
     9121 gcttgtcaaa ggtcaagtta aagatgttca tgccatgatt tggattttgg atgccttgtt
     9181 tatccttaac tacatcagca tggccttata atagaatgac ccagggggat ttcccccctt
     9241 ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa ttgttgaatc
     9301 gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt cccctagtgg
     9361 ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg atagttactg
     9421 gcctttcaat tgtggttctg gctctattta ttatgggagc tcgtaaaacc aagttagcta
     9481 gttttaattt ttcttttttt agagctaaag atttggcacg tttgggcttg agttatttag
     9541 ttattgtcgg gtcaaatata cttggttcta tcttgttgca actgtcaaat gagacgacaa
     9601 cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt tctagcttct
     9661 tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg attgttccta
     9721 aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt gtgtttgctt
     9781 tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg tcgacagttc
     9841 tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt cacatgattg
     9901 ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg acattaggaa
     9961 tttctgtgta aaagttttta tgtaggaacc gacctctttc tactagggaa agatgaatgc
    10021 aatcgtgtcc atctttttct ttttatggta aaatagaaaa ataatatgat gaaaatcctt
    10081 gagggagtga ccgatatgtc aagtaaagcc aatcatgcaa agacagttat ttgcggaatt
    10141 atcaatgtaa ccccagactc cttttcggac ggtggtcaat tttttgctct tgagcaggca
    10201 ctccagcagg ctcgtaaatt gatagcagaa ggagccagta tgctcgatat cggcggagaa
    10261 tcgactcggc cgggcagtag ctatgttgag atagaagagg aaatccagcg tgttgttcca
    10321 gtgatcaaag cgattcgcaa ggaaagtgat gtccttattt ctatcgatac ttggaaaagt
    10381 caggtggcag aggctgcttt ggctgctggt gccaatctag ttaatgatat cactggtctc
    10441 atgggcgatg aaaaaatggc ccatgtggtt gctaaagctg gagcgaaagt agtcatcatg
    10501 tttaatccag tcatggctcg acctcaacat cctagttcgc ttatcttccc tcattttggc
    10561 tttggtcaaa cctttacaga aaaagagtta gctgactttg aaacattgcc aatcgaagac
    10621 ttgatggtgg ctttctttga acgagcacta gcgagagcgg cagaagctgg tattacacca
    10681 gaaaatatcc tgttggatcc aggaattggc tttggtctga ccaagaaaga aaatctcctc
    10741 cttttacggg acctggataa actacatcag aagggctatc caatctttct cggagtgtcg
    10801 cgcaagcgat ttgtcatcaa tatccttgaa gaaagtgggt ttgaagtcaa tcctgagaca
    10861 gagcttggtt tccgaaatcg ggacacggct tcggctcatg taactagtat cgctgcgaga
    10921 cagggtgtag aagtggtgcg cgtgcatgac gtagctagtc acaggatggc agttgaaatt
    10981 gcctctgcca ttcgtctggc tgatgaagcg gaaaatttag atttaaaaca atataaataa
    11041 gatgaaagaa attgaaaaca atcagtggat tgctaactac cggacggatc aaccgcattt
    11101 tggattggaa cgaatggtgg aactgttagc tttgcgtggc aatccccatt tcaaactcaa
    11161 ggtcctccat atcggaggga ctaacggcaa gggctcgact attgcttttt tgaaaaagat
    11221 gctagaaaag ctagggctga gagttggcgt gtttagctcg ccctatctca ttcattacac
    11281 agaccagatt agcatcaatg gggaatcgat ctcagaagcg aggctagaag ctctcatggc
    11341 agactatcag tctttgctgg agggagaagc ggtcgccaat ttacagggca caaccgagtt
    11401 tgagattatc acagccctgg cctatgacta ctttgcctca gagcaagtag atgtggccat
    11461 catggaagtt ggcatgggtg gacttttgga tagtaccaat gtctgtcagc ccattttgac
    11521 aggaattaca actattggct tggatcatgt ggccctactt ggtgacacct tggaggccat
    11581 agcagagcag aaggcaggta ttatcaaaca agggataccc ttggtaacag ggcgtattgc
    11641 tccagaagcc ttgactgtga ttgaccgcat tgcggaaggg aaagatgcgc cgagacttgc
    11701 ctacgggaca gattatcagg ttcgtcatca agaaagtgtg gtgacagggg aagtctttga
    11761 ctatacaagt gctgtcagac aaggtcgctt ccagactagc ctgcttggtt tgtaccaaat
    11821 agagaatgct gggatggcca tagctttact tgatactttt tgtcaagaag atggtcgaga
    11881 gctagcaagc aatgactttc ttggtcaagc cttggaagaa acaagttggc cagggcgttt
    11941 ggaaatcgtg tcaagagatc ccttgatgat tttggatgga gcccataatc cccatgctat
    12001 caaggccttg ttggtaacct tgcaagaacg ttttgcggat tatcataagg aaatcctctt
    12061 cacttgtatc aaaaccaaag ccttggagga tatgttggac ttgctgggag ccatgccaga
    12121 taccgagctt actctaacac attttgcgga tagtcgggcg acggatgaaa gcgtgctgaa
    12181 agaggcagct aagtctagaa atctcagcta ccaagattgg catgattttc tagagcagaa
    12241 tttgacagat aaaaaagaag agaaacaaac agttaggatt gtcacaggtt ccttgtattt
    12301 cttgagccaa gtgagggcct atctgatgga gaggaagaac gagaatggat acacaaaaga
    12361 ttgaagcagc tgtaaaaatg attatcgagg ctgtaggaga gaacgctaat cgcgagggct
    12421 tgcaggaaac acctgctcgt gtagcccgta tgtatcaaga gattttttca ggtcttggtc
    12481 aaacagcaga ggaacatttg tcaaaatcct ttgaaattat tgacgataat atggtggtag
    12541 aaaaggatat ctttttccat accatgtgtg aacaccactt cttgccattt tatggtagag
    12601 cgcacattgc ctacattcca gatggtcgtg tggcaggctt gtctaagcta gcccgtacgg
    12661 ttgaagttta ttcgaaaaaa ccacaaattc aagaacgttt gaatatcgaa gtggccgatg
    12721 ccttgatgga ctatctaggt gctaaaggag cctttgttgt cattgaggcg gaacatatgt
    12781 gtatgagtat gcgtggtgtt agaaaaccag gcactgcaac cttgacgaca gtagctcgtg
    12841 gtctatttga aacagataag gacctccgcg accaagctta tcgtttaatg gggctataaa
    12901 aagaatccgc ttcaagcgga tttttctaga aaggaatcat tatggatcaa ctgcagatta
    12961 aggatttgga aatgtttgcc tatcatggtc tttttcctag tgagaaagaa ttggggcaga
    13021 aatttgtcgt ttcagccatc ctatcctatg atatgaccaa ggcagctaca gacttggatt
    13081 taacagcctc tgtccattac ggagaattat gtcagcagtg gacgacttgg tttcaggaaa
    13141 cgagtgaaga tttgattgaa acggtagcct ataaactggt ggaacgtacc tttgagtctt
    13201 atcctcttgt ccaagaaatg aagttggaac tgaaaaaacc ttgggcaccg gtgcatttgt
    13261 cactagatac ttgctcggta accattcatc gccgcaagca acgagccttt atcgccctag
    13321 gaagcaatat gggagataaa caagcaaact tgaagcaagc cattgacaaa ctgcgagctc
    13381 gtggcatcta tattctcaaa gagtccagtg tcttagcgac ggagccttgg ggtggagtgg
    13441 agcaggatag ctttgccaat caagtggttg aggtggaaac ctggctacca gcacaagact
    13501 tgttagaaac cttgttagcc attgagtcag agctgggacg ggtgagagaa gtgcattggg
    13561 gacctcgttt gattgatttg gacttgctct ttgtggagga ccagatcctt tatacagacg
    13621 acctcatatt gcctcatcct tacatagcgg aacgcctttt tgtccttgag tccttacagg
    13681 aaattgcgcc tcattttatc catccgacat taaaacaacc gatccgcaac ttgtatgatg
    13741 ctttgaaaaa atagaaaaac tctagttttc agttacttgc aactgaaggc tagagttttt
    13801 aaaataggtc attttcttct gggaggagga tagtttctct accgtacatg tctaaaacca
    13861 gtactcttgg gggataacga gggtcgaaag gatggttaaa gtcaaaatca atggctgtag
    13921 ggaggtgttg acttgaaaag tggaaggtaa tctttccttg gttattaagc aattgaaact
    13981 cgagttcttc ttccaattca aagacatttt ttaagaaatg atcgatgata taccaaaaag
    14041 agtcaatgat gtcatcgggc aagctggtaa caatgccaaa actagcagac cgcatgtggg
    14101 tattggtaaa agccatatct ctgtcccctt tcttttccct tatcatacag caaataggat
    14161 taaaaatcaa gaaaaggtga ttttttgaaa aggattttaa ctacagggaa aaataaggaa
    14221 aaaaattccc aaaaatctac cgaagttaat aggtaaattc ccaaattaac ttgattatat
    14281 aactttcagt tactttgaga agttaccgaa aaatattttt catatctatt gacttttagg
    14341 ggtgaaattt ggtatgatag taggcggtat tgtttacccc atttgaaagg ccccggaacc
    14401 ttccaaatac ttttcgatgg gaaggaacac ccatcaccgt aaacaaaaat cgaactatat
    14461 ataggagaaa tcatgaacaa aacaacattt atggctaaac caggccaagt tgaacgtaaa
    14521 tggtacgtag ttgacgcaac tgatgtacca cttggacgtc tttctgcagt agttgctagc
    14581 gtacttcgcg gaaaaaacaa accaacattt acaccacaca ctgatacagg tgacttcgtg
    14641 attgttatca atgctgaaaa agttaaattg actggtaaaa aagcaactga taaaatctac
    14701 tacactcact caaaccaccc aggtggattg aaacaaatct ctgcaggtga acttcgttct
    14761 aaaaatgcag tacgtttgat tgagaaatca gttaaaggta tgcttccaca caatacactt
    14821 ggacgcgctc aaggtatgaa gttgaaagta tttgttggag ctgagcacac tcatgctgca
    14881 caacaaccag aagttcttga catttcagga cttatctaag gaaaggaaca aataaagtat
    14941 gtcacaagca caatatgcag gtactggacg tcgtaaaaac gctgttgcac gcgttcgcct
    15001 tgttccagga actggtaaaa tcactgttaa caaaaaagat gttgaagagt acatcccaca
    15061 tgctgacctt cgtcttgtca tcaaccaacc attcgcagtt acttcaactg taggttcata
    15121 cgacgttttc gttaacgttg taggtggtgg atacgctggt caatcaggag ctatccgtca
    15181 cggtatcgct cgtgcccttc ttcaagtaga cccagacttc cgcgattcat tgaaacgcgc
    15241 aggacttctt acacgtgact cacgtaaagt tgaacgtaag aaaccaggtc ttaagaaagc
    15301 tcgtaaagca tcacaattta gtaaacgtta attcgaaaga attactatac ttatacagag
    15361 cacctttcgg ggtgttcttt ttttatactt tcttactaaa ttggtgcaat tgacacagtt
    15421 gttgcgactt tagttgctta caaatgtggc tgcaacctga caaggtcagt tgcctcaaaa
    15481 cgctaatcaa tacaattata tcaatgtttc aaagcactca aaggtttgcc ctatgggtgc
    15541 ttttttcgtg tttttttgaa aagtttacct tatttttata gtaaggtgaa ataagaatag
    15601 gacaaaccga ggatagtcaa atcgaattct aacaatgttt tagaagtaga ggtgtactat
    15661 tctagtttca atctactata ttatggataa tgcaagattc catagaatgg gtaagttaga
    15721 actcttgtgt gaagagtttg ggtataaact tttacctctt cctccctact cacctgagta
    15781 caatcctatt gagaaaacat gggctcatat caaaaagcac ctcaaaaagg tattaccaag
    15841 ttgcaatacc ttttatgagg ctcttttgtc ttgttcttgt ttcaattgac tataaatcgc
    15901 tataagaaaa aatcatttta ttggtataaa gaagtgattg aaagtaatgg cgaaacgtta
    15961 gataattagt tcataaaaaa caagtttaga tcctcatcta aacttgtttt tttaaaattg
    16021 aaggatgatt ttggaggata tgagatgaca ttgactattc atgtatatta taaaggcgat
    16081 ggagattgtg caataaagtt tgcaagagaa atgcttgaat ctgggcttgt cgcagaaatt
    16141 agatgtcaaa aaggtaattt gaaatacgaa tattttttac caattgaaaa agagggaatt
    16201 attctcctta ttgatcagtg gataaatcaa gaagctttag atgaacatca tcaatcaaat
    16261 acaatgcaga aaatcttaga tttaagaaaa aaatatcact tgcagatgca agttgaacgt
    16321 tatatagaag atgattctgg gatgccagaa agcgataagt cgtttataga cacagggaat
    16381 tagaattatt gtgagagttt ttgtagtttg aaagtattga aaatcgtaaa gatatcatta
    16441 cgagaataca agaagatatt gttctatttc cattaaaaat tacttctttc cttaataata
    16501 aggaaaaaga atacgttttc atcttttggt ttgaggttta taataagaat atcaaagtca
    16561 ggaggaaaaa agatgactac ttttaaagat ggatttttat ggggtggtgc tgttgctgct
    16621 catcaacttg aaggcggatg gcaagaaggt ggcaaaggaa ttagtgttgc tgatgttatg
    16681 actgctggtc gccatggagt agctcgtgaa attactttgg gagttttaga gggtaaatat
    16741 tatccaaatc atgaggcgat agatttttat catcgttata aagaagacat agcacttttt
    16801 gctgaaatgg gattcaagtg cttccgtacc tctattgcat ggacacgtat ctttccaaaa
    16861 ggtgatgagt tagagccgaa tgaagaagga ttacagtttt atgataatct ttttgatgaa
    16921 tgcttaaaga atggtattga acctgtcatc actctatctc attttgaaat gccttatcac
    16981 ttagtgaccg aatatggtgg ttggaaaaat aggaaattga ttgatttctt tgctcgtttt
    17041 gcagaagtcg tatttaaacg ttacaaagat aaggttaaat attggatgac tttcaatgaa
    17101 atcaataatc aagcgaatta tcaggaagat tttgcaccat ttactaactc aggtattgta
    17161 tatgaggaag gtgataatag agaagcaatt atgtatcaag cagcacatta cgaattagtt
    17221 gcttctgcac gagctgtaaa aattggtcat gagattaatc cagattttca aataggttgt
    17281 atgattgcga tgtgtccaat ttatccagtt acttgcaatc ctaaggatat cttaatggca
    17341 atgaaagcta tgcagaagcg ttattatttt gctgatgtgc atgttttagg taaatatcct
    17401 gagcatattt tcaagtattg ggaacgaaaa ggtatttcag ttgattttac tgaccaggat
    17461 aaagaagatt tacttggtgg gactgtagat tacattggtt tcagttacta tatgtccttt
    17521 gctatagact ctcatcgtga aaataatcct tattttgatt atcttgaaac agaagattta
    17581 gtgaaaaata attatgttaa ggcttctgaa tgggagtggc aaattgatcc agaaggttta
    17641 cgttatgcgt taaattggtt tacagaccac tatcacttac cactctttat tgttgaaaat
    17701 ggttttggag ctatagatca agttgcagca gatggtatgg tacatgatga ttatagaatt
    17761 gaatatctag gtgcccatat tcgtgaaatg aaaaaggctg tagttgaaga tggtgttgat
    17821 ttaatgggtt atactccatg gggatgtatt gatttggttt cagctggtac cggtgaaatg
    17881 cggaaacgtt atggctttat ttatgtagat aaagatgaca atgggaaggg aagttataat
    17941 cgttccccga aaaaatcttt tggctggtat aagaaagtta ttttatctaa cggtgaatca
    18001 gtagaatagt ataaacaaac tgagattatt ctcagtttgt ttagcatatt gaggagacat
    18061 atgattggaa gtattgcagc aattttaaca acatttgcat ttttaccaca agtttttcgt
    18121 gtagttaaga caaaggacac aggatctatt gctctaggta tgtatgttat gcaagttatt
    18181 ggtattgcat tgtggcttgc tcatggtatt cgtataggag acttgccttt gattttagca
    18241 aatagtgttt catttctact ctcaggaata attttatttt ataaattgaa gtataaataa
    18301 tttttttcca tatcatttag gaaaatgagg gaattgtcat tgaaaacgct ttattttata
    18361 ataaaaatag ataacaaata agccaactta gcacagcttt gattggattt aagaaaagga
    18421 gaaaatatta tggcaaaagc tttaattatt tgtgcagcag gaatgtcttc atcacttatg
    18481 gcacagaaaa caacagagtt tctaaaagga aaagggaaag atattgtagt tgatgctatt
    18541 agtgctactg aaggagggaa agctatcgca acagcagctt ttgatttgta tcttgtcagt
    18601 cctcaaacaa aaatgtactt taagcaattt gaagaggctg gttctaaagc aggaaaacca
    18661 gttgtacaaa tacctcctca agcctatatt cctattccaa tgggaattga aaaaatggct
    18721 aatttgattc ttgagaatat ttgatgaaca catgaaatgt caataaatat ttaagttaag
    18781 ataaattgtt ttgagtttga tataaattga tttaagtgta taatatgctt caatatatga
    18841 aaacatacgt tttaggaggg aatgaatgtg ttaaacatta aagagaaaga tatccttcaa
    18901 tttttaataa aaaataagga acgttttgtt acaagcaaag aactggcaga atatttatcc
    18961 tgttcagata gaactgtccg taatgtactg aaattaattg agaagacaat gattattcaa
    19021 ggagtccggt tgatttcaaa acaaggtcaa gggtatcaaa tattttttga gaatcaaggc
    19081 gcttaccagg agtttagaca aacttatgaa ctggaagaag actatacgaa aactgcggtt
    19141 tcaaaaggtg atgatcgttt agtatttatc ttaaataaat tattatttga gcaagttcca
    19201 gttctttttg atgatttagc tgatgaactt tacgttagtc gttcaacatt atctcatgat
    19261 ttcagaaaga tacgagtgat gttatcagag tataatttgt ccattgagag tagggcgaat
    19321 aaaggagttt atgtctcagg cgaggaacgt gataaacgac gttttatcat aaattatttc
    19381 ctagagaatc aattttttaa aacaatacat tgctatgtaa aatttaactt ttttgctcaa
    19441 actgttccat tagaagaatt tgctagaatt gttttggatg aatgccaaga ggccaaccta
    19501 aaactatctg attttgtact acagaattta gtagttcaca tagcattgtc tgtgattcgt
    19561 ttaaaatccg gatttgaaat aaaaaatata gactgtcaga tgactgatga tgcaatagag
    19621 agaaaggttg ctcaaagaat tctttctaaa gtaagagaag taacaaatca ggaatttcca
    19681 gttcaggaaa tagactacat tactttgcat ttgttagcta agagtcaaca atgtcaaaaa
    19741 aatcagaaga atatttctga agaagtttta aaaaaatctt tatttaaaac atttcagaat
    19801 ttaggattag atgatatgta taacttttct tcagatttcc aactaattga aggattgata
    19861 actcatctaa tgacactaca agtacgttta gaaagccgga ttaccttaaa taaccctttg
    19921 gtagatgaaa ttaaacagaa ttatagtgat atattcttta tgactagaga aattcttgca
    19981 aatatggaca agttcttgga gtggacaata tcagatgatg aagtagcata tgtaagtctt
    20041 cactttttag ctgctatgga acgtagcaaa gagagtacta agtttaatat tcttgctatt
    20101 tgtgcaacag gatttggtgc agcccaaatg ttaagaaatc gtttggaaac ggagtttggg
    20161 aagcgagtag aagttgttga tgtaataggc tattatgaat tgaatcaaga aaaacttaaa
    20221 ggaatagatt ttatagtgtc agctgttgat ttatcaaatc tatattttca aattccagtt
    20281 tttaaagtta gtgtgtttct taagagtgat gagatggaaa tgattagaaa agctatggat
    20341 cagatgcaag tttctagtta tgtacaatca tcaaagatta ataaatttga aaacaacagc
    20401 tttagacagt attttagtaa agaaaatttt ttaatatgta ctgaatcaga caaggtaaat
    20461 ttacttgaaa agatggttga gagtttatct gttggtgaat caaatgagtt tgaacaatct
    20521 ttactttatg gaattaaaca gcgcgaagaa ttaagttcag ttgttttttc tgaaaaaatt
    20581 gcagttccgc atcctattca gccctttggt acagagggaa aggtttcggt tgcaatctgt
    20641 aaagattcgt tactctggga taatcaaagt tcatatgtcc agctagtatt tcttctatct
    20701 ccatcaatat atgggaacga aggtttggca actgtgacta aaaagatagt ctctctgaca
    20761 gagaatgatg agttgcaaaa tcagctaata tcttgcaata actttgaaga ttttattagc
    20821 atatttgaga agataaaata ggaggttcat atgaatcaag aggaactgca ggttgcagca
    20881 tttgaaatta tcctgcattc gggaaatgca aggtcagaaa tacatgaagc atttgcaaaa
    20941 atgagagaag gtagttttga tgatgcagaa agtaaattaa atcaatcaaa tgagataatt
    21001 cttgaagcgc atcatgcaca aaccaaactc ttgcaagaat acgcaagtgg agtggaaatt
    21061 aaaattgaaa ttatcatggt acatgctcaa gatcatttaa tgaccactat gacattatta
    21121 gaagtagcaa aggaaatgtt agctctttat aagaaagtta actaaatatg tgttgttata
    21181 taaggaggaa atgatatgga taaaaaagaa cgacaaaaga ttgaacaaca acgtcgagag
    21241 atggctctaa ctaatacttt ttttaatcga tatcttcttc tacgttattc aatagcactc
    21301 ttcttttttg ggaatattta ttggcttttg aatcagttta ttaatccctc gcctattatt
    21361 attttcccca ttatgctcat agtattttct attttagcaa ctgttgaaca atttaaactc
    21421 tatggaaata ggaaagaaaa gttgggaata acactaatgt ttgttagaat acaaatactt
    21481 atttcaatag gattacttgt tttaacttgg acaagttggt ttaagaatct ttttccgatt
    21541 tttgaaaata accaagtagc acgtttattt gtttttgtag ttcttctatt aggtttagtt
    21601 ctgagtttgt tagacattag aagaattaaa aaaatttata aacgaacaga taaggcttat
    21661 caacaatttg tccaattgga aaagaactca cttagtttat aatcctgatc tagtataatt
    21721 tgtatttgaa actagtcttt agaaagtaaa aattattatg ttttattaag gaggtctatt
    21781 tatggatcaa caaaacgggt tgtttggttt tcttgaaaac catgttatgg gaccaatggg
    21841 caaacttgct cagtttaaag tagtgcgtgc tatcacggct gcaggtatgg ctgctgtacc
    21901 atttactatt gtaggatcaa tgtttttggt attcagtatt ttgccacaag ctttctcatt
    21961 ttggccaatt gtggcagata ttttctctgc ttcatttgat aaattcacat cactttacat
    22021 ggttgcaaac tatgcgacta tgggttctct atctctttat ttcgttctat cacttgcata
    22081 tgaattgaca aaaatttatg cagaggaaga agaactcaat atgaatcctc ttaatggtgc
    22141 cttgctcgcc ttgatggctt ttgtcatgac agtaccgcaa atcatttttg atggtggaat
    22201 gatgaagact gtgacaagtc taaaagaagg tgcagtaatt gcagatggat gggcaatggg
    22261 aaatggagtc gcacgttttg ggacaacagg gatttttacc gcaatcatta tggcaattgt
    22321 gactgttctt atttatcgta tgtgtgttaa acataattgg gttattaaaa tgcctgaagc
    22381 tgttccagaa ggagtttctc gtggatttac cgctttggtt ccgggatttg ttgttgcatt
    22441 tgttgttatc tttatcaacg gtcttcttgt agcaatggga acagatattt ttaaagtcat
    22501 tgcaattcca tttggttttg tatccaatct gactaattcg tggattggtt taatgattat
    22561 ttatctattg actcaactac tttggattgt aggtatccac ggtgcgaaca ttgtttttgc
    22621 atttgttagt ccaattgctc ttgctaacat ggctgaaaat gctgctggcg ggcacttcgc
    22681 tgttgcaggt gaattttcta atatgtttgt aattgcaggt ggttctggtg caactttagg
    22741 actatgttta tatattgctt ttgcctctaa atctgaacag cttaaagcaa taggacgagc
    22801 atctgtagtt ccagccttat ttaatattaa tgaaccatta atttttggat tacctattat
    22861 ctataatcca gccttggcta taccatttat tttagcacca atggttactg ctactattta
    22921 ttacgtagcg aattctctaa actttattaa gccaattatc gcacaggttc catggccaac
    22981 tccagtaggg attggagctt tcttagggac agcagatctt cgagctgtat tagttgctct
    23041 agtatgtgca tttgcagcat tcttagtcta tcttccattc atccgtgtat atgatcaaaa
    23101 attggtgaaa gaagagcaag gtatctaata agtaaaaaag tatactcgat gatagaatcc
    23161 atatagttta aataatgagt gttaatatta gcagtgaaga ggtcttttta agatattctt
    23221 ctctgctttt tcatattttt tcgctatgta gggtatgaag caaaatagaa agtagttcga
    23281 atagttgata aacaggaaac tgctgttatt taaaaaaaac aataaagtaa agtatgttat
    23341 cgtagaatac gatacaatag taaaaaagca aaaagaatgc gttttatatt tgggtttgag
    23401 gtttataaaa taggataagc gtgctgaaaa cttagatatg acaaacaaaa taaaattttt
    23461 aaaagctaca tagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata
    23521 tagataaaga aaagatgaca atcatgggaa tagcttttga aaacagatcc gtttttaaga
    23581 gtgtttggta tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg
    23641 ttgaaaaatt acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta
    23701 tgagtcttat gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct
    23761 aagaaataag caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag
    23821 agtttgaaat tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca
    23881 actgcataag cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta
    23941 aaagatattt tgtccactac attttttcaa ttgactatta tttgtcatag atataacaga
    24001 tagaacagat agaacattgc attcagaata atgaaaaacg catcaaaaat ggtgcgttct
    24061 gtttttatgc taccataaaa ggaggaaaac aaattgaaaa tttttaaggg agagttttat
    24121 cgaatctctg tattaacaga caagctagta aggttagaat actctcaaac tggaagtttt
    24181 gaggatagaa cgacacaact tatctataat agagattttg gccaagtttc gttagattat
    24241 atcgagacat caaacgtact agatattatg acggactatt ttcatctgca ctttaataaa
    24301 ggagaattta acgccgaaaa tttatttata gaattaaaag gaaattttgc cgtatatggt
    24361 agtcgctggt attttggtga atctattgaa acgttaaaag gaacagctcg gactctggat
    24421 aaggcagatg gagcaatctc gttagaagat ggaattatta gccgaaatgg tatagcctta
    24481 ttggatgatt ctcaaggatt tatttgggat gaacaatctg gttatattga gagagaaaat
    24541 caaattgacc tgtatttctt tgcctatggg catgattata gaggagcaat cagagacttt
    24601 taccatttga ctggttcaac acccttgttg ccaagatatg ctttaggcaa ttggtggagt
    24661 agatattggc cttatacgtc ggatgaatac ttggatttaa tagacagatt tgaaacagag
    24721 aaaattccat tatctatcgg tgtgttagat atggattggc atataactga cattccagct
    24781 cgttttggaa gtggctggac aggatatagt tggaatagaa acttaatacc aaatccagaa
    24841 cagttattgc aacaacttca tgatagaaag ttaaaactct ccttaaatgt ccatcctgct
    24901 gatgggatac gggcttatga agaagcttat cctcaaatcg caaaacggtt ggggttaaat
    24961 gtagaactag aagaacctgc tatttttgat ttttttaatc cctcttttag ggaagcctac
    25021 tttaaagatg ttcattatga gctagaaaag cagggagtag atttttggtg gattgactgg
    25081 caacaaggga cacaaggtat gctagatcca ctttggcttt taaaccatta tcactatcag
    25141 gatagttgta aaaatgcaga aggtggtttg attttatcaa gatatgcagg tcctggtagt
    25201 caccgctacc ctgttggttt ttcaggggat actattatta gttggaattc cttaaggttt
    25261 caaccctatt ttacagcgac agcatctaat atcggttata gttggtggag tcatgatatc
    25321 ggtggacata tgttggggga ttatgacgaa gagctacaaa ctagatggct acagtttggt
    25381 gtttttagtc cgattactcg attacatagt tctagaagtc cttttaatag taaagaacct
    25441 tggttctttt cagaaacaac atctaagatt atgaagaaat accttcgttt gagacatcag
    25501 atgattccct atctatatac catgaatgta aagacacatg aggaaggtgc cccattaatc
    25561 agtccaatct attatttcta tccagagaat gatgagagct ataatgttcc aaaccaatac
    25621 ttttttggaa cagaactgat ggtggctccc attgtagaaa agatggattt gacattccaa
    25681 tctgcaaaag tagatgtatg gttccctgaa ggtgaatggt atgacttctt ttcagagaaa
    25741 aaatacacag gtggtgtgaa gttaagtgtt tatagggaca tctcgactac gcctgtgttt
    25801 gcaaaaagtg gtgcaatcat tcccttggtt ggttctgaga taggtatggg tgttgattta
    25861 cctgaggttg tagattggta tgtattccca gggaaacaac atttttttga aatgcttgaa
    25921 gatcaaaatg gtcaaagata taaaacaaga ttatcaatcg attgggaaat gggaatggta
    25981 gagttagcat tacaaggaga ttctagtatc gttccaagca atagaaaaca tagaattcat
    26041 tttaaaggaa cgaatgtgtc tataattgaa ttgccaaata agaatgatac agctaaattt
    26101 gaatggaaag ataataaaag gacatcttta aatgacgaag tttttagact actaaagaca
    26161 gcttctcttc catatgaatt aaaagataga ttgttaaatc aattcatcaa tgcgaaaaac
    26221 tctcatgact taatgaatat cttgcatcat caggataagg aattgagagg gcgtttgttg
    26281 gaaatgatat ttactagcca aaactaattg aaataattag aaagtcattt gtttagtgta
    26341 tatgaagatt ctgtatggta ttcgttatca ctggtcacat tgaaaatgtg aaataagcac
    26401 ctacaacata gactttacaa cacttcatgt ttcatatcat ggggtgtttt tctatttaag
    26461 tcaaagccca tcaaaaaatc tcactattca tcaggttaaa ggaaacctaa tcatagtgag
    26521 attgtgaatt atagtagagt ttgtatcgcc tcttcaattt gttttgggtc tgtttttgaa
    26581 gaaaagcgtt caaagacttg cccatctcga ccgatgagaa acttagcgaa attccattcg
    26641 attcgttttc ctagtgggcc ggatttctgg tcttttaacc agacatagag agggtctgct
    26701 tccttaccgt tgaccttaat cttggcaaaa cgtgggaagg tggtttgaaa atgtaggcta
    26761 cagaaggcgt tgatttcctc tgcgctgccg ggtgcttgtc ccataaactg attgcaaggg
    26821 aaatccaata tttcgaagcc ctgatcttga tagcgttcat agagttcttg aagtccctgg
    26881 tactggggcg ttaaaccaca tccagtagca gtgttgacaa tcaagagaac tttgccacga
    26941 tagctatcca agggagttgc ttggttgttt tggttcaaaa cggaaaaatc ataaagtgaa
    27001 gtcatgaggg cctcttttct ttttctacat tgtaacagtt tttacttttt tcgtcgagtc
    27061 ggatggaaga tattgttgaa gaataagcct tcaatatgat agaaaccgtt tacaaataac
    27121 tttaaaaatg gtatgattta attaaaccgg tttacttagt tgctataaat ctctaatttg
    27181 agatttagtt cctattgatt ttacaatatg tttattggag tgtatacatg caaacaaaaa
    27241 caaagaagct cattgtgagt ttgtcttcac ttgttttatc aggattttta ttaaaccatt
    27301 atatgacagt tggagcggaa gaaacgacta cgaataccat tcagcaaagc cagaaggaag
    27361 ttcagtatca gcaaagggat acaaaaaatt tagttgaaaa tggtgatttt ggtcagacgg
    27421 aggacggaag cagtccgtgg acaggaagca aagctcaggg gtggtcagct tgggtagacc
    27481 agaagaatag tgcagatgcc tcaactcgag tcattgaggc taaggatggg gctatcacta
    27541 tctcaagcca tgagaaatta agggcagcgg ttcaccgtat ggttcctatt gaagctaaga
    27601 aaaagtataa actgcgtttc aagattaaaa cagatcataa agtcgggatt gccaaagttc
    27661 gtatcattga ggaaagtgat aaggacaagc gattgtggaa ttctgcaacg acgtcaggaa
    27721 caaaggactg gcagaccatt gaagcagact atagcccgac tttagatgtt gataaaatca
    27781 agctggagtt attctatgaa acaggaactg ggactgtttc ctttaaggat attgagctgg
    27841 tagaggtagc agaccagcct tctgaggact atcaaacaga taaacagctt gaggaaaaga
    27901 ttgatttacc aattggaaaa aaacatgttt tttctcttgc ggactatact tataaggtag
    27961 aaaatcctga cgttgcttca gtcaaaaatg gaattttaga acctcttaag gaagggacaa
    28021 ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa gattcctttg aagattctag
    28081 cctctgttaa ggatgcatac acagaccgtt tggatgactg gaatggcatc atcgctggga
    28141 atcaatacta tgattctaaa aatgaacaga tggccaaatt aaaccaggaa ttggaaggaa
    28201 aggtagctga tagcctatct agtatttcaa gtcaggcgga ccgcacctat ttgtgggaaa
    28261 aattttcaaa ttataaaatg tctgcaaatc tgactgccac ttatcggaaa ttggaggaga
    28321 tggccaagca agtgaccaat ccttcttctc gttattatca agatgaaact gtcgttcgaa
    28381 cagtcaggga ttccatggaa tggatgcata aacatgtcta caatagtgaa aagagcattg
    28441 ttgggaactg gtgggattat gaaatcggta cacctcgtgc catcaacaat accttgtctc
    28501 tgatgaaaga atacttctct gatgaggaaa ttaaaaaata tacagatgtg attgaaaaat
    28561 ttgtaccaga tcccgaacat ttccgaaaga cgactgataa cccatttaag gctctaggtg
    28621 gaaacttagt tgatatggga agagtaaaag taatagctgg tttactgcgt aaggatgatc
    28681 aagaaatttc ttctaccatt cgctcgattg agcaagtgtt caagttggta gaccaaggtg
    28741 aaggttttta tcaagatgga tcctatatcg accataccaa tgttgcctat acgggtgctt
    28801 atgggaatgt tttgattgat ggcctgtctc aactgttgcc agtcattcaa aagaccaaga
    28861 atccaatcga taaagataaa atgcaaacca tgtaccactg gattgataaa tcgtttgctc
    28921 ctttgctggt gaatggagag ctgatggata tgagtcgtgg acgctcgatc agtcgtgcaa
    28981 atagcgaggg gcacgtggcc gcagtagaag tactaagagg gattcaccga atagcggata
    29041 tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt gaagaccatt gttcaatcgg
    29101 atagttatta tgatgtcttt aagaatttga agacttataa ggatatcagt ttgatgcaat
    29161 ccttgttaag tgatgcagga gtcgcaagtg ttccaagaac aagttaccta tctgccttta
    29221 acaagatgga taaaacagcc atgtacaatg cagagaaagg gtttggattt ggcttgtcac
    29281 tcttttccag tcgtaccttg aattacgaac acatgaacaa ggaaaataaa cgtggttggt
    29341 atacgagtga tgggatgttc tatctttaca atggcgattt gagtcactat agcgatggct
    29401 actggccaac agttaatcca tataagatgc ctggtacaac agagacggat gctaagagag
    29461 cggatagcga tacaggtaaa gttttaccgt ctgctttcgt tggaacgagc aaactagatg
    29521 atgccaatgc gacagcaacc atggatttca ccaactggaa tcaaacattg actgctcata
    29581 agagctggtt tatgctaaag gataagatcg cctttttagg aagcaatatc caaaacactt
    29641 caacagatac tgctgcaact acaattgacc agagaaaact ggaatcaagt aatccatata
    29701 aagtctatgt caatgataaa gaagcctccc ttacagaaca agaaaaggat tatcctgaaa
    29761 cccaaagtgt ctttttagaa tcatccgatt cgaaaaagaa tattggttac tttttcttta
    29821 agaagagttc aatcagtatg agtaaggctt tgcaaaaggg agcctggaag gatatcaatg
    29881 aaggacagtc agacaaggaa gttgaaaatg aatttcttac gattagtcag gctcataagc
    29941 aaaatggaga ttcttatggc tatatgctca tccctaacgt gggtcgtgcc accttcaatc
    30001 aaatgataaa agagttagaa agtagcctca tcgaaaataa cgaaaccctt cagtctgttt
    30061 atgatgccaa acaaggagtt tggggcattg tgaaatatga tgattctgtc tctactattt
    30121 ccaaccaatt ccaagttttg aaacgtggag tctataccat tcgaaaagaa ggggatgaat
    30181 ataagattgc ctactataat cctgaaaccc aggaatcagc tccagatcag gaagtcttta
    30241 aaaagctaga gcaagcagct cagccacaag tacagaattc aaaagaaaag gaaaaatctg
    30301 aagaggaaaa gaaccattcg gatcaaaaga atctccctca gacaggagaa ggtcagtcaa
    30361 tcttggcaag tctagggttc ttgctacttg gggcgtttta tttattccgt agaggaaaga
    30421 acaactaatt tgttcatcat ctagatgaat tacatgaaac tgtggaaaat agaaaaaatc
    30481 cgaagaaggc caaatatctt cggatttttc ttttaaaaaa ggataagttg atacttatcc
    30541 tttttacttc attatgtgac tatagcgttt tgaaactaga ataggacatc ataactgcta
    30601 aaagatttct ataaattcat ttgattttcc taatcaattt attcgtatcc tatttcactc
    30661 tactatatta gtccgtctcg cacctcacgg agcgagacaa aacaaccacc cgctatgcgg
    30721 gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga tacaataaag gtgttcaatc
    30781 cacttgtaaa gcgaaaggag aaaaaatatg gcacaaaagg ctcatagttt atctcacaca
    30841 aagtggaggt gttctatcac attgtgttca cccctaagta tagacgaaaa gtcatctata
    30901 atcaatatag aagtagttta ggcgaaatat ttcatcgctt gtgtagttat aaaggtgttg
    30961 aaatgatcga gggtcactta atgccagacc atgtacacat gttagtcagt attccactaa
    31021 ggctaagtgt ttcgagtttc atgggttatt taaaaggaaa aagtgcactc atgatgtttg
    31081 acaaacacgc caatctcaag tacaagtttg ggaatcggca tttctgggtg gaaggttatt
    31141 atgtaagtcc agtagggctt aatgaagcca caattaagaa atatagtcaa gattaaagaa
    31201 attatccagt ggatgatttc ttcacgagta tgaaaatttg agaactagta aagtatgata
    31261 tatagtaaaa tgaaataaga acaggacaaa atcgatcagg acagtcaaat cgatttttaa
    31321 caatgtttta gaagtagagg tatactattc cagtttcaat ctactatagc actagataaa
    31381 ttgagtgtaa aagaatatga ggatcccttt agggatagtg gtaagtaata ccaaagtctc
    31441 ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtaaa agccagcgtc
    31501 tttaggcgct ggctgatgat ttgggcttat agctctggga taaaccaccc gttagacggg
    31561 tagttatgat tttatctgag tgtaatatac tgttgggcaa tctcgctgat gcggtcaaag
    31621 ttgccttggg aagcgagttt attgagttcg ccaccaattc caacggcatc tgcaccagca
    31681 gcgaaccatt gagggatgtt gtttaggccg actcctccgg ttaccattac ggaaacttgt
    31741 gggatcggtg ccttgactgc agagatatat gctggactga gagtactacc tgggaagagt
    31801 ttgatgattt cactaccggc ttcaagtgca gtcgtgatct ctgtgagggt aatacagcct
    31861 ggaatgtacg gtgtgctgta gagattgcac attttcgcag tttcagcatg gaaagatgga
    31921 gaaacaacgt aatttgctcc agctagaatg gcatctctag cagttacggc atcaagcaca
    31981 gtacctgcac cgatacaaac actctgatcg tcctgataca agtctacaag ttccttgatg
    32041 atttgtcctg catactgatt ggtataggcg atttcaatag ctttgatacc gcccttgata
    32101 caagcaatcg aggcttgtag tccttcttcc tttgtatttc ctcgaatgac agcgacaatt
    32161 ttctgttttt ttagttcaat aatcgtatct gatttggtca tgtaattctc ctaacgaatg
    32221 atatcttgtg catttgccag taaattttca atactagttg cggaagtgga gagatggtct
    32281 cctggaagag tgcatttgag agttgcgctc gcaactgcaa agtcaatggt agtttttagg
    32341 gaggaatgat ggagtagttg gtaaagggca ccagatataa aggcatcccc gctaccaatt
    32401 cgttgataga ctgcagtttt tagttggaca gactcttcaa atcgttcttc cagagcatag
    32461 gcttgataga catttttgtc ttgctcatca ctagatcgga gggtatggaa aatggccttg
    32521 aaaccatagg cttcttttaa aagtcgcatg cgattttcca cctcttctag gctagcactg
    32581 tctcttggaa acatctctag attttggtca tcaatcatga gaggatcaat accgaagcaa
    32641 tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg cttctaggac tgaaatcatc
    32701 tttgttctca gattgagatc cattgaaacg acaattcctc ggcgcttggc ttcttccaag
    32761 agtaggagaa ggatcgcacg gacctcttga ccgatagcta tggtgattcc actaaaatga
    32821 aaatggctaa tcccctgaaa gagagaatcc atatctagca tgtttggccg aatctggctg
    32881 atactcgtat gcttacgatc gtagaaaact tcactttgac gacaaccaaa gccgttctcc
    32941 aaatagtaga ggccgattcg atcgccaagc cgacagattg aactggtatc gatttggtgc
    33001 tgtttcaaga atgtgagaaa acgatctcca atctcgttgg cagggagtgc ggtaaagact
    33061 ttcgttgaga tacccagggc ttgcaaatta caagcgatgt taatttctga tccgccaaaa
    33121 taagtcgaac tggcaacatg atcgccgata ctggtggcat ctaatggtga gattcgaatt
    33181 aatggttcgc caaacagtaa tattttcgtc atccattagt tcctttctgg tttagaatag
    33241 ctttacttgg ctaatacttc tttcaaataa gcagcgactt catcatcttg gcagttttca
    33301 aagaagtatt cttggaagta tttgccagag atggtgtctt tgaggaagtc ttggtcgatt
    33361 gttttaagga tggtcatcaa atcattgtgg gtgatttgtt tcacctcgtt taagatacga
    33421 gcgttgcgtt gttcagggat tacacgttct cttgggtagc caccgcccat ttcttcagca
    33481 aataagcgtt caaacatcaa tttgagggtc agttctgccc cccagccaaa tcctttggca
    33541 taagggatag acaaggcgtt accaccattg atttgagaat aaaggtaagc gtcagttggg
    33601 tccactgcta gaccacagac aacaccaggg aagctgttta aagcaagcat agcccctaca
    33661 cccgtaccac agccggtaac aacaaagtca actgcctttg tatttaaaag gatggcagcc
    33721 attagtccgt tctgcacata agttaattga ctttctcctt cttctccacg cataccatag
    33781 ttaaataatt ggtagtcttt tttatctgtc gcttctttta gactatcgta aataatgtga
    33841 ttcttgctag cttgactatt ttcattgatt aatgcgattt tcataagatc ttctttctat
    33901 ttttactcag gttgttttcc gatgtaggct aagataccgc catctacata taggatgtgg
    33961 ccattgacaa aattgctggc atcactagcg agaaagacag cagggcccat caaatcttca
    34021 ggatttcccc aacgtgcagc aggtgttttt gcaatgatga actggtcaaa tgggtggcga
    34081 gaaccatctt cttgcaactc acgaagaggt gctgtttgag gagtggcaat ataacccggt
    34141 ccaattccgt tacattggat attggctcca ccgtattcag acgcaatgtt gcgggtcaac
    34201 attttcaagc cccctttagc agcagcataa gcgctaactg tttcacgtcc cagttcgctc
    34261 atcatcgaac aaatattgat aatctttcca tgccctttct ttatcataga aggaataact
    34321 gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga tgaccttacg gaaatcagcg
    34381 gcgctcattt cgcacattgg aactcggcgg ataataccag cgttattaac gaggatgtca
    34441 atgacaccaa cctcttgttc gatttgcttg accatggctt ggataccgtc ctcgtctgtc
    34501 acgtcacaga catatccatg ggcttcgatg ccaacttcac gataagcttc aatcccttta
    34561 ttgaccagat cttgattgat atcgttaaag acaatagtag cgccggcttc agcgtaggat
    34621 ttggcaatag caaatccaat tccataagaa gcgccggtga tgagagcaat ttttcctttt
    34681 aaagaaaact gctcaattga gaatgatgta tttgtcattt gatacttcct ttcaaatttg
    34741 ttaagacttc tctataacca aattatattc tagcaaaccg gttttgtcaa taaataaata
    34801 tttttattta taaaaagatt tgttttcctg aaaaacggaa tattttgaaa tttctgttta
    34861 ttaaaatggt taaaaagata atgaaagcgc taatattttt ttaaaaaaac tattgacaag
    34921 ataaaaataa aggattacaa tggggaatat aaagtaaacc ggtaaaccta aacaagaaag
    34981 gagaaaagat gaaaattgta cttgtagggc atggacattt tgctacaggg atttatagtt
    35041 ctttacaatt gattgcaggt aatcaagaaa atgtggaggc gattgacttt gtggaaggaa
    35101 tgtcagcaga tgaactcaag caaaaaatct tacttgcaat ttcaaatgaa gaagaagttt
    35161 taatcctaag tgatctcttg ggaggatcgc cattcaaggt ttcttctacc ataatgggag
    35221 aaaatccagt caaaacaatg aatgttctct cgggtttgaa cttagccatg ttaatggaag
    35281 cagtctttgc tagaatggct catagctttg atgaggttgt taataaatca gtagtggcgg
    35341 cccagggcgg agtcgtaaat ggtaaagaat tgttttcaac ggatgcagag gaagaagatt
    35401 tcgaatcggg tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa
    35461 atcgcctgag cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat
    35521 cgataaggtt attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac
    35581 gccagctacc tttgataatg tctatccaat catggataac acggaatgga ccaatggttt
    35641 ctggacagga gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat
    35701 cgctcataaa aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca
    35761 ccatgatctc ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga
    35821 tggagaggct agagaagcaa ccttgaaagc tgcagataag ttgattgaac gctatcaaga
    35881 aaaaggtggt tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat
    35941 tatcgactgc ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca
    36001 aaaatactac gatattgcag aaagtcattt ctatgcttca gctaataatg taatccgtga
    36061 tgacgcttcg tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg
    36121 tgtaacgaga caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt
    36181 ctatggtatt cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa
    36241 gggtgtgacc aattatttct tgaatcgtct gccaaaagat catgtgtcct attgggattt
    36301 gatttttaat gatggtagtg ctcaatcacg agattcttca gcaacagcta tcgccgtctg
    36361 tgggattcat gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa
    36421 acatgctatg catgccatgc ttcgttcctt gatcgaacat tatgcaaatg atcaatttac
    36481 ccctggtggg acaagtcttc tccacggtgt gtactcatgg cattcaggta aaggagtgga
    36541 tgaaggcaat atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga
    36601 ctggaaccta tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta
    36661 tcgatgaacg gttgattcat ggacaaggac aactttgggt aaaataccta gcttgtaata
    36721 cggtcattgt tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa
    36781 cagttgtgcc agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca
    36841 ttcacaaggc taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt
    36901 taaccttggt agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg
    36961 cccctggtaa agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc
    37021 tcaaggaatt aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa
    37081 atgatggagc tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc
    37141 gattaatgta tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat
    37201 gctgttagga atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct
    37261 aggtgatctg cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt
    37321 cggtgttggt gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac
    37381 cttgatggct atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac
    37441 tccgattgct gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc
    37501 gcctgaaacg gcgatgaagc acttgaaaaa ccataatttg aagaaattca agtttactct
    37561 aaatgcaaca atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct
    37621 ttcaatggat accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt
    37681 gacagttgct ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc
    37741 taagaaagag ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat
    37801 cccaacaatt ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa
    37861 gccaaaaaca gcgaatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat
    37921 taacaaaacg tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta
    37981 actatagtaa ctatcaaggg ttgggatatg ccaatgtgat gtatcctgct ttgaaaaaac
    38041 actatggaga ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata
    38101 ataccaaccc acacttcctg ccttttatta ccagcttgca tcttgtaatg ttggaaaatg
    38161 gccgtccggc aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta
    38221 ttggggattc tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt
    38281 ttgctcaaga aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt
    38341 taacagcgat taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg
    38401 ataaactaag cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg
    38461 taattgctgg tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag
    38521 gggaagttaa agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg
    38581 ttgctccagc tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa
    38641 agaaatggac aacatataaa ctcgttattt taacagttgt catcggaatt atcggaagct
    38701 ggcttaagat tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc
    38761 agtgagtccc cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa
    38821 acagacggag caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt
    38881 attgtctgga attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat
    38941 tgcaaaaggt gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact
    39001 gctttttaag tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt
    39061 tgaaagagtc gatggaaacc aatgtcgtga ttatatcttg tcgcactgtt caaaagacta
    39121 tgagaaagtc aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc
    39181 ttgggatatg gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt
    39241 atttgaagat gatccagaat gggcttatat gctcaatcga caagaatatc tcttgcagtt
    39301 tatgataggg tatgtggtag aaggagataa ggactatatt caaaagtgca agttctttct
    39361 atttgattgg attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt
    39421 ggatacgggt attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga
    39481 catgctagag gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt
    39541 tatgaaaagc tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat
    39601 tccgatgctt gctatctatt atttcttttc agataagatg gacctagaag aagcttacca
    39661 ttttgcttca gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca
    39721 gtttgaacag tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct
    39781 cttgcttcca gacttgcaag atagttaccg agagttgctg gaaaagatgg cgacctatat
    39841 tcaaatgatg acaggcttag atggacgaac tttggctttt ggtgatagcg attctacaga
    39901 aacgacagaa attttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg
    39961 tctggatgtt aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg
    40021 actgcaggaa tttgaaaaga gagcttggca gcctaagtcc atgatctttg aagactctgg
    40081 acatgtctgc attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag
    40141 tgcccatagc catagtgacg agaatagttt ttgcttacag tatcaaggac aacctatttt
    40201 catagatgct gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc
    40261 ttggagtcat tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg
    40321 ggaatatgaa tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca
    40381 ttatattgaa ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa
    40441 aatcctcatg ttggtagagg atgtctggct cttggtggat gacatcaggt gtcaaggtca
    40501 gcatgaggcg ttgactcagt ttatccttga caaggatgtg acctatcaag atgggaaaat
    40561 caatcagttg agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc
    40621 taaatacaat gagcttgaaa gaagtaacaa actcaccaag cgccaattct ttgagaatca
    40681 gatgctggat tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta
    40741 ccagacagat gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac
    40801 agacaagctg attctgttat taagcgagga tatttgtgta ggtgaaaaat tgtgcctcgt
    40861 tgacggaaca aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat
    40921 tcgcttgcag tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt
    40981 aggaggtgtt ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag
    41041 acctcgaaaa caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag
    41101 acacgtgaaa agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg
    41161 cgtagcttaa actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac
    41221 agtttctcaa accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag
    41281 gtaatgatag gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg
    41341 cttctcttgg gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct
    41401 cgtatcatcg atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac
    41461 cggactagct gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt
    41521 atcgaaaaag gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact
    41581 cggattgagc gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc
    41641 agtctaacca ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa
    41701 gaaatcgatc ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta
    41761 gtctttaccg ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt
    41821 gacaatacgg agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc
    41881 tttgaggaag gacaacaggc tacaaagatt ttgattgatc agattgaagg ccgtaatcaa
    41941 gaagaaaggc aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat
    42001 gaaggaaaat gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta
    42061 ggtgggatta tttgcttatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt
    42121 tttgatctac ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga
    42181 tggttacgac taggaatatt gaaaatttcc attggacagg gttggttaaa agttgtggaa
    42241 aggatatgag gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt
    42301 tctcaagtcc tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag
    42361 aaacagctcc tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgttca
    42421 gtagtctagc tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca
    42481 atacgaagtg agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt
    42541 ttaaaaatat gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg
    42601 gtatcaatga gtggaattat aaaaaatatc actgttccat aaatcgaacc tgctttaaga
    42661 ccaggataac gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg
    42721 atttttctta gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa
    42781 aatagaaccg agaatacttg atacaccatt tcttatagtg agaagagaat gaaaatagtc
    42841 ctgaccttca tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa
    42901 gaacaaacct gctttcagac ctgggtagtg tagttgcttg ctttctttct cattcagcat
    42961 atctggttca atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc
    43021 gatgagggca atcactaaaa tcagaggagg atagattaga gccacttctt gagggtattt
    43081 ataggctaga aggagtggaa taagatttcc gaaaatcatc agataaaaga ggacgataaa
    43141 gacttggttc ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat
    43201 accgtatgtg cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct
    43261 tttttaaaaa tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag
    43321 attgagacag agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg
    43381 tctcgagaca ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa
    43441 ttctttcaca cgattcatct ggtctccttt ctgatttatg tcgtatatat ttgactatat
    43501 tatagtcttt taaacataaa gtgtcaagta tatttgacat attttttgaa gaaatagtag
    43561 tctccttgtc ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa
    43621 gatatgacaa aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt
    43681 gacgtaaaac ctgacggtat ctacgttgat gcgactttgg gtggagcagg ccatagcgag
    43741 tatttattaa gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat
    43801 gccattgaca atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt
    43861 atcaaggata acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt
    43921 gatggaattt gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt
    43981 ttttcttata aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca
    44041 gcctatgaag tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac
    44101 ggtgaggata aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag
    44161 ccgattgaga caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa
    44221 ctcaagaaga agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat
    44281 gatgaactgg gagcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat
    44341 ggtagaattt cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc
    44401 aaggaagctt caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag
    44461 cccaagatgg aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc
    44521 aataaccgct cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga
    44581 aaaagatggc agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt
    44641 tttcgcgtgt ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca
    44701 ttagtattat ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca
    44761 atgcgcagat agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac
    44821 tattacgtgc agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg
    44881 aaaatattag aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga
    44941 ccaaaaatcg gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat
    45001 tatctgtctt tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca
    45061 ctcgctttgg aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag
    45121 ttcctgccaa acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa
    45181 cctcctataa tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc
    45241 tttacgtaga aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca
    45301 tggaagaatc ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg
    45361 gagcaaaggg aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag
    45421 ctgcagaggt caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac
    45481 aatttgcttc tagttttatc ggcctagctc agctccatga aaatgaagat ggaagcaaga
    45541 gcttgctggg aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg
    45601 gcattattac ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt
    45661 cccaacgaac gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct
    45721 ttatggaaac ccagatggat tcttttcaag agaaggtaaa aggaaagtac atgacagcga
    45781 ctttggtcag tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg
    45841 cagatacaaa agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta
    45901 actatgagcc aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata
    45961 cctttccagg aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc
    46021 gagattggga cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt
    46081 ttgcacactc aagtaacgtt gggatgaccc tccttgagca aaagatggga gatgctacct
    46141 ggcttgatta tcttaatcgt tttaagtttg gagttccgac ccgtttcggt ttgacggatg
    46201 agtatgctgg tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac
    46261 aagggatttc agtgacccag acgcaaatga ttcgtgcctt tacagctatt gctaatgacg
    46321 gtgtcatgct ggagcctaaa tttattagtg ccgtttatga tccaaatgat caaactgctc
    46381 ggaaatctca aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc
    46441 ggactaacat ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca
    46501 caggcaagcc aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc
    46561 agattgctga cgagaaaaat ggtggttatc tagtcgggtt aaccgactat attttctcgg
    46621 ctgtatcgat gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac
    46681 ctgaacatta ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt
    46741 cagctatgaa agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc
    46801 aacaaagtcc ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag
    46861 aattgcgtcg caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca
    46921 gttctgctga agaagggaag aatcttgccc cgaatcagca agtccttatc ttatctgata
    46981 aagtagagga agttccagat atgtatggtt ggacaaagga gactgctgag acccttgcta
    47041 agtggctcaa tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg
    47101 ttcgtgctaa cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat
    47161 atgtttattt ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg
    47221 gcctttatcc aattttatag aaaggcgcaa attacaggcc agcagatgca tgaggatgtc
    47281 aaacagcatc aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact
    47341 tctgttttgg ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatatggga
    47401 atgattttgt tcatcttggt cttgtatggc ttggtcggat ttttagatga ctttctcaag
    47461 gtctttcgta aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta
    47521 ggtggagtta tcttctatct tttctatgag cgcggtggcg atatgctttc tgtctttggt
    47581 tatcaagtgc atctagggat tttctatatt gtcttcgctc ttttctggct agtcggtttt
    47641 tcaaacgcag taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt
    47701 agtttgtctg cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg
    47761 attcttgcca tgattggtgg tttgctcagt tttttcatct ttaaccataa gcctgctaag
    47821 gtctttatgg gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg
    47881 gctctccacc aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact
    47941 tctgttatga tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg
    48001 acgcctgtac atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc
    48061 gagtggaagg ttgacttctt cttttgggga gttgggcttc tagcaagtct cctgaccctt
    48121 gcaattttgt atttgatgta agaatggcac cctgatgttt cagggtgttt ttgtgtttaa
    48181 atacacaatg aaaatcaaag aacaaactag aaagctaact ttaggctgct caaaatatag
    48241 tagattgaaa ctagaatagt acacctctac ttctaaaaca tttttagaaa tcgatttgac
    48301 tgtcctgaac gatttatcct gttcttattt cattttacta tacagttttg agatggttga
    48361 tagaactgac gaagtcagct caaaacactg ttttgaggtt gtagacaagg cgaagctgat
    48421 gtggtttgaa gaggttttcg aagagtgtaa aaaaatattg gtcagttaaa gtcaaaactc
    48481 ttgacctttt ctgaccaatg tagtatatta tgaacgtaag gtaaatgaaa gccttactag
    48541 aacacttatt taaagtaaaa tagaaagagg tgagtctatg tttcatctag caatcttcag
    48601 aggtaaagat agtctactcc tgcttgaaaa agaaaaacca gaaatagtac gtagggtagc
    48661 gatctagcta gtctaaattt tttaaaacaa tggtcaaaga tagtcaatat cagtaatcat
    48721 aactaagtaa acaaaaagag gtaaagaata tgaataacaa ctttaataat tttaataaca
    48781 tggatgattt atttaaccaa ttgatgggtg gtatgcgagg atatagttct gaaaatcgcc
    48841 gttacttaat taatggacgc gaagtcacac ctgaggaatt tgctcactat cgtgcgactg
    48901 gtcaattacc aggaaatgca gaaactgatg tgcaaatgcc acaacaggca tcaggtatga
    48961 aacaagacgg tgtccttgca aaactaggtc gaaacttaac agcagaagcg cgtgagggca
    49021 agttggatcc tgttatcgga cgaaacaagg aaattcaaga aacatctgaa atcctctcac
    49081 gccgcaccaa gaacaatcct gttttggtcg gagatgcagg tgttggtaag acagcagttg
    49141 tcgaaggtct agcgcaagcc attgtgaacg gagatgttcc tgctgctatc aagaacaagg
    49201 aaattatttc tattgatatc tcaggtcttg aggctggtac tcaataccgt ggtagctttg
    49261 aagaaaatgt ccaaaactta gtcaatgaag tgaaagaagc agggaatatt atcctcttct
    49321 ttgatgaaat tcaccaaatt cttggtgctg gtagcactgg tggagacagt ggttctaaag
    49381 gacttgcgga tattctcaag ccagctctct ctcgtggaga attgacagtg attggggcaa
    49441 caactcaaga cgaataccgt aacaccatct tgaagaatgc tgctcttgct cgtcgtttca
    49501 acgaagtgaa ggtcaatgct ccttcagcag agaatacttt taaaattctt caaggcattc
    49561 gtgacctcta tcaacaacac cacaatgtca tcttgccaga cgaagtcttg aaagcagcgg
    49621 tggattattc tgttcaatac attcctcaac gtagcttgcc agataaggct attgaccttg
    49681 tcgatgtaac ggctgctcac ttggcggctc aacatccagt aacagatgtg catgctgttg
    49741 aacgagaaat cgaaacggaa aaagacaagc aagaaaaagc agttgaagca gaagattttg
    49801 aagcagctct aaactataaa acacgcattg cagaattgga aaggaaaatc gaaaaccaca
    49861 cagaagatat gaaagtgact gcaagtgtca acgatgtggc tgaatctgtg gaacgaatga
    49921 caggtatccc agtatcgcaa atgggagctt cagatatcga acgtttgaaa gatatggctc
    49981 atcgcttgca agaaaaggtg attggtcaag ataaggccgt agaagttgta gctcgtgcta
    50041 tccgtcgtaa ccgtgctggt tttgatgaag gaaatcgccc aatcggcagc ttcctctttg
    50101 tagggtctac tggggttggt aagacggagc ttgctaagca attggcactc gatatgtttg
    50161 gaacccagga tgcgattatc cgtttggata tgtctgaata cagtgaccgc acagctgttt
    50221 ctaagctaat tggtacaaca gcaggctatg tgggttatga tgacaatagc aataccttaa
    50281 cagaacgtgt tcgtcgcaat ccatactcta tcattctctt ggatgaaatt gaaaaggctg
    50341 atcctcaagt tattaccctt ctcctccaag ttctagatga tggtcgtttg acagatggtc
    50401 aaggaaatac agtaaacttc aagaatactg tcgttattgc gacctcaaat gctggatttg
    50461 gctatgaagc caacttgaca gaagatgcgg ataaaccaga attgatggac cgtttgaaac
    50521 ccttcttccg tccagaattc ctcaaccgct ttaatgcagt catcgagttc tcacacttga
    50581 ctaaggaaga cctttctaag attgtagatt tgatgttggc tgaagttaac caaaccttgg
    50641 ctaagaaaga cattgacttg gtagttagtc aagcggctaa agattatatc acagaagaag
    50701 gttacgacga agtcatgggg gttcgtcctc tccgtcgcgt ggttgaacaa gaaattcgtg
    50761 ataaggtgac agacttccac ttggatcatt tagatgctaa acatctggaa gcagatatgg
    50821 aagatggcgt tttggttatt cgtgagaaag cctaagatag aattttgagg ataaaaaaga
    50881 aggagccagc tgaaaaaaac tggttccttt ttaggtacga caggcatgtc gtatagtaga
    50941 agtgtattat tccagtttca atatactata gtagctcaga agtcggtact taaacgtgct
    51001 atatcaaaac cagtccttga aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa
    51061 cgacatgcgt taaaagttag ttgaaccgcc gtatgccgaa cggtacgtac ggtggtgtga
    51121 gaggggctag agattatccc ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc
    51181 tgaaatccct tgttccaaga tgagttttgc ccattcttta gcagagaaga ggctgtggtc
    51241 cttgtagttt ccgcaagatt cgatggttgt ccctgggaca tcttcccaag tagtagtttc
    51301 agcgatttcc ttgagcgaat ccttgataac agctgcgatt ttagcactgg tgtgacgtcc
    51361 ccacataatc atgtggaagc ctgtgcggca accaaatggt gaacagtcaa tcatgccgtc
    51421 aatgcgggta cggatgagtt tggctaagag gtgctcgata gtgtgaaggc cggcagtagg
    51481 gatagagtct tcgtttggtt gcaccaagcg aatatcataa ttggagatga tgtctccttt
    51541 tggtcctgtt tcttccccaa tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag
    51601 ttcaaaactt tcgacaataa cttcttttga catggtaaat cctttcagtt ttcttctctc
    51661 attatatcat aaaggttgtt cctgagacag agagaaaacc tctccgaggc tagagaggtt
    51721 gaaatcttta cttacgatat aagcggtcgt attggtagta tgggtcaaag gttacgttga
    51781 tacccagttt acgaaggaca ttcttgtctt catcagtcaa gatgatggtt gagtgggctt
    51841 cgcttccttt gaggttgccg agttcttcca tagcgcgggc agcatcagga ttttctgtag
    51901 ctgtgatagc aagtgcaatc aggatttcat ttgaatgaag gcgtggattg cggctaccga
    51961 gatgatcgat tttaagacct tggattggct taacaacttc aggctcgatt agttttactt
    52021 ctttagcgat gtcagctgat tttttgatgg cattgatcaa ggcagcggct gtagggccaa
    52081 agagttctga gttcttacca gtgatgattt ccccatttgg caattcaaag gctagggctg
    52141 gtccaccagt ttcttctgct ttttggcgcg caacgacagc aaccttacgg tctgcaggtg
    52201 tgataccgag gtcgttcatg agtaactcaa ttttcttgac ggcagcttcg ccaacttttt
    52261 cagctttgaa gtcaagaact gtttgatagt aacggcggat gatttcttgt ttagaagctt
    52321 cgacagcagc ctcgtcatct gtaatagcga aaccaaccat gttgacaccc atatctgtcg
    52381 gtgaagcgta tggtgatttt ccgagaatac gttccaacat gcgcttgagc actgggaaga
    52441 tttctatatc acggttgtag ttgacagtgg tttctccata ggtttgaaga tggaaggggt
    52501 caatcatgtt gacatcatca aggtcagctg tggcagcttc ataagccaag ttaactggat
    52561 gatgaagggg aagattccaa acagggaagg tttcaaattt agcgtagcca gatttgatgc
    52621 cattgatttg gtcgtggtac atattggaca tacacgttgc caattttcca gaaccgggtc
    52681 caggagcggt tacgacaatc aagttgcgac tggttttgat gtagtcgttt ttgcccatgc
    52741 cttctgggga aatgatgtga tccatatccg tcggatatcc tttgattgga taatgaagat
    52801 aagaatcaat tccgtttttc tcaagttgat tgcggaaggc atctgcagcg ggttggccag
    52861 cgtattgtgt aatgacaacg gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca
    52921 aacgaagaac ttcttggtca taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa
    52981 tgttgctagc attaatggca atcacaacct caacctgctc tttcaattct tgcaagagct
    53041 tgattttgtt gtcaggttca taaccaggaa ggacacgagc agcgtggaaa tcttctaaca
    53101 ttttaccgcc aaactctaag tagagcttgc cgtcaaattg gttaatgcgt tccaaaatat
    53161 ggtcgcgttg taaattcaaa tattgttcag aactaaaagc ttgttttttc atttttttac
    53221 ctctgacctc tattataata aaaaattgga agttaggaaa ctacggagct aaaaaagaaa
    53281 ttaaaaagat taagcaaacg cttgcacaaa attttaaaaa gtgttatcat atactataga
    53341 ttatgaaaat aatgaggtaa acagatgcaa gaaaaatggt ggcataatgc cgtagtctat
    53401 caagtctatc caaagagttt tatggatagt aatggagatg gagttggtga tttgccaggt
    53461 attaccagta agttggacta tctagctaag ttaggaatca cagcgatttg gctttctccc
    53521 gtttatgaca gccctatgga tgataatggc tacgatattg ctgattatca agcgattgca
    53581 acgatttttg gaaccatgga ggatatggat caactgattg cggaagctaa gaagcgtgac
    53641 attcgtatca tcatggactt ggtggtcaat catacctcgg atgagcatgc ctggtttgta
    53701 gaggcctgtg aaaattctaa tagccctgag cgagattact atatctggcg ggatgagcct
    53761 aacgatttag attctatttt tagtggatct gcttgggaat acgatgaaaa atctggtcaa
    53821 tactatctcc actttttcag caagaaacag ccggatctca actgggaaaa tgaaaaactt
    53881 cgccagaaaa tttatgagat gatgaacttc tggattgata aaggtattgg tggtttccgt
    53941 atggatgtta ttgacatgat tggcaaaatt cctgacgaga aggtagtcaa taatggtcct
    54001 atgctccatc cctatctcaa ggaaatgaat caggcgacct ttggagataa ggatctcttg
    54061 acagtagggg agacttgggg agcaacgcca gagattgcca agctctactc tgatccaaag
    54121 gggcaagaat tgtctatggt cttccagttt gaacatatcg gtcttcagta tcaggaaggt
    54181 cagcctaaat ggcactatca aaaagaactg aatatcgcta agttaaaaga aatcttcaac
    54241 aaatggcaga cagagttagg agttgaggac ggctggaatt ccctcttctg gaacaaccat
    54301 gacctccctc gtattgtctc aatctgggga aatgaccaag aataccgcga aaaatctgcc
    54361 aaagcctttg caatcttact tcatctcatg agaggaactc cttatatcta ccaaggtgag
    54421 gagattggga tgaccaacta tccgtttgaa acactagatc aagtagaaga tattgaatct
    54481 ctcaactatg cgcgtgaggc tcttgaaaaa ggtgttccga tgcaagaaat catggacagt
    54541 atccgtgtta ttggacgtga caatgcccgt acccctatgc aatgggacga gagcaaaaac
    54601 gctggtttct caacaggtca accttggttg gcagttaatc caaattacga gatgatcaac
    54661 gtccaagaag cgctggcaaa tccagattct attttctata cctatcagaa actggtccaa
    54721 attcgcaagg agaatagctg gctaattcga gctgactttg aattgcttga tacggctgat
    54781 aaggtctttg cttatatacg taaggatggc gaccgtcgct tcctagttgt ggctaacttg
    54841 tccaatgaag agcaagactt gacagtagaa ggaaaagtca aatctgtctt gattgaaaac
    54901 accctagctc aagaagtttt tgaaaaacaa atcttagttc catgggatgc tttctgtgtg
    54961 gaattactat aaatattttt tgcagaaaaa tttaaaattg aaatcatata aaaacaaggg
    55021 aggactgtat aaaaagcaga aatcctttgt tttttataac caaggtttat aaactttcat
    55081 tttcgaaatt caattaactt tacaaattcc cactattaag gagaaagaag atgaacataa
    55141 agaagcgtgt tcttagtgca ggcctgactt ttgcatctgc tttgctttta gctgcttgcg
    55201 gccaatcagg ctcagataca aaaacttact catcaacctt tagtggaaat ccaactacat
    55261 ttaactatct attagactat tacgctgata atatagtcaa ttgaaacaag agcaggacaa
//
LOCUS       DBEJZJ010000012        50821 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000012 DBEJZJ010000000
VERSION     DBEJZJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.12"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(90..1256)
                     /gene="recA"
                     /locus_tag="ACL3R8_000896"
     CDS             complement(90..1256)
                     /gene="recA"
                     /locus_tag="ACL3R8_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR1313799.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(1311..2567)
                     /locus_tag="ACL3R8_000897"
     CDS             complement(1311..2567)
                     /locus_tag="ACL3R8_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR1313800.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHVFNLVRKALLSD"
     gene            complement(2652..3668)
                     /locus_tag="ACL3R8_000898"
     CDS             complement(2652..3668)
                     /locus_tag="ACL3R8_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR1313801.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3676..4194)
                     /locus_tag="ACL3R8_000899"
     CDS             complement(3676..4194)
                     /locus_tag="ACL3R8_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR1313802.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4184..4627)
                     /gene="tsaE"
                     /locus_tag="ACL3R8_000900"
     CDS             complement(4184..4627)
                     /gene="tsaE"
                     /locus_tag="ACL3R8_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR1313803.1"
                     /translation="MYTKNEEELQALGESLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4713..5333)
                     /locus_tag="ACL3R8_000901"
     CDS             complement(4713..5333)
                     /locus_tag="ACL3R8_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313804.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5716..6579)
                     /locus_tag="ACL3R8_000902"
     CDS             complement(5716..6579)
                     /locus_tag="ACL3R8_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1313805.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            6768..6938
                     /locus_tag="ACL3R8_000903"
     CDS             6768..6938
                     /locus_tag="ACL3R8_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR1313806.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            7388..9403
                     /locus_tag="ACL3R8_000904"
     CDS             7388..9403
                     /locus_tag="ACL3R8_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR1313807.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTTGEGLLSYNLILLSISLFFTQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            9405..10037
                     /locus_tag="ACL3R8_000905"
     CDS             9405..10037
                     /locus_tag="ACL3R8_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313808.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(10965..11378)
                     /gene="ndk"
                     /locus_tag="ACL3R8_000906"
     CDS             complement(10965..11378)
                     /gene="ndk"
                     /locus_tag="ACL3R8_000906"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR1313809.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11489..15166)
                     /gene="rpoC"
                     /locus_tag="ACL3R8_000907"
     CDS             complement(11489..15166)
                     /gene="rpoC"
                     /locus_tag="ACL3R8_000907"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR1313810.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15199..18810)
                     /gene="rpoB"
                     /locus_tag="ACL3R8_000908"
     CDS             complement(15199..18810)
                     /gene="rpoB"
                     /locus_tag="ACL3R8_000908"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR1313811.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19226..19296
                     /locus_tag="ACL3R8_000909"
     tRNA            19226..19296
                     /locus_tag="ACL3R8_000909"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19258..19260,aa:Cys,seq:gca)
     gene            complement(19494..20825)
                     /locus_tag="ACL3R8_000910"
     CDS             complement(19494..20825)
                     /locus_tag="ACL3R8_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR1313812.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21116..21940)
                     /gene="endA"
                     /locus_tag="ACL3R8_000911"
     CDS             complement(21116..21940)
                     /gene="endA"
                     /locus_tag="ACL3R8_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR1313813.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(21979..22167)
                     /locus_tag="ACL3R8_000912"
     CDS             complement(21979..22167)
                     /locus_tag="ACL3R8_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR1313814.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22160..23443)
                     /gene="murA"
                     /locus_tag="ACL3R8_000913"
     CDS             complement(22160..23443)
                     /gene="murA"
                     /locus_tag="ACL3R8_000913"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR1313815.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23467..23697)
                     /locus_tag="ACL3R8_000914"
     CDS             complement(23467..23697)
                     /locus_tag="ACL3R8_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR1313816.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(23755..24792)
                     /locus_tag="ACL3R8_000915"
     CDS             complement(23755..24792)
                     /locus_tag="ACL3R8_000915"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR1313817.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(24776..25264)
                     /gene="coaD"
                     /locus_tag="ACL3R8_000916"
     CDS             complement(24776..25264)
                     /gene="coaD"
                     /locus_tag="ACL3R8_000916"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR1313818.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25254..25793)
                     /gene="rsmD"
                     /locus_tag="ACL3R8_000917"
     CDS             complement(25254..25793)
                     /gene="rsmD"
                     /locus_tag="ACL3R8_000917"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR1313819.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(25858..26850)
                     /gene="asnA"
                     /locus_tag="ACL3R8_000918"
     CDS             complement(25858..26850)
                     /gene="asnA"
                     /locus_tag="ACL3R8_000918"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR1313820.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(26961..27644)
                     /locus_tag="ACL3R8_000919"
     CDS             complement(26961..27644)
                     /locus_tag="ACL3R8_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGR1313821.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(27700..28440)
                     /locus_tag="ACL3R8_000920"
     CDS             complement(27700..28440)
                     /locus_tag="ACL3R8_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR1313822.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            28474..28752
                     /locus_tag="ACL3R8_000921"
     CDS             28474..28752
                     /locus_tag="ACL3R8_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR1313823.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            28830..29756
                     /gene="yidC"
                     /locus_tag="ACL3R8_000922"
     CDS             28830..29756
                     /gene="yidC"
                     /locus_tag="ACL3R8_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR1313824.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(29831..30625)
                     /gene="pflA"
                     /locus_tag="ACL3R8_000923"
     CDS             complement(29831..30625)
                     /gene="pflA"
                     /locus_tag="ACL3R8_000923"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR1313825.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(30751..32001)
                     /locus_tag="ACL3R8_000924"
     CDS             complement(30751..32001)
                     /locus_tag="ACL3R8_000924"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR1313826.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32068..32895)
                     /gene="purR"
                     /locus_tag="ACL3R8_000925"
     CDS             complement(32068..32895)
                     /gene="purR"
                     /locus_tag="ACL3R8_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR1313827.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33162..34103)
                     /locus_tag="ACL3R8_000926"
     CDS             complement(33162..34103)
                     /locus_tag="ACL3R8_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR1313828.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34093..35349)
                     /gene="rmuC"
                     /locus_tag="ACL3R8_000927"
     CDS             complement(34093..35349)
                     /gene="rmuC"
                     /locus_tag="ACL3R8_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR1313829.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35351..36013)
                     /locus_tag="ACL3R8_000928"
     CDS             complement(35351..36013)
                     /locus_tag="ACL3R8_000928"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR1313830.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(35976..36632)
                     /gene="rpe"
                     /locus_tag="ACL3R8_000929"
     CDS             complement(35976..36632)
                     /gene="rpe"
                     /locus_tag="ACL3R8_000929"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR1313831.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(36643..37521)
                     /gene="rsgA"
                     /locus_tag="ACL3R8_000930"
     CDS             complement(36643..37521)
                     /gene="rsgA"
                     /locus_tag="ACL3R8_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR1313832.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(37523..38395)
                     /gene="rsmA"
                     /locus_tag="ACL3R8_000931"
     CDS             complement(37523..38395)
                     /gene="rsmA"
                     /locus_tag="ACL3R8_000931"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR1313833.1"
                     /translation="MRIADYRVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(38526..38834)
                     /locus_tag="ACL3R8_000932"
     CDS             complement(38526..38834)
                     /locus_tag="ACL3R8_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313834.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(38827..39468)
                     /locus_tag="ACL3R8_000933"
     CDS             complement(38827..39468)
                     /locus_tag="ACL3R8_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313835.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(39470..41500)
                     /locus_tag="ACL3R8_000934"
     CDS             complement(39470..41500)
                     /locus_tag="ACL3R8_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR1313836.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(41577..41873)
                     /locus_tag="ACL3R8_000935"
     CDS             complement(41577..41873)
                     /locus_tag="ACL3R8_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR1313837.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(42193..43104)
                     /locus_tag="ACL3R8_000936"
     CDS             complement(42193..43104)
                     /locus_tag="ACL3R8_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGR1313838.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(43176..43736)
                     /gene="rnmV"
                     /locus_tag="ACL3R8_000937"
     CDS             complement(43176..43736)
                     /gene="rnmV"
                     /locus_tag="ACL3R8_000937"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR1313839.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(43736..44509)
                     /locus_tag="ACL3R8_000938"
     CDS             complement(43736..44509)
                     /locus_tag="ACL3R8_000938"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR1313840.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(44814..45566)
                     /locus_tag="ACL3R8_000939"
     CDS             complement(44814..45566)
                     /locus_tag="ACL3R8_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGR1313841.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEATPEYKLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPN
                     TGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(45742..45876)
                     /gene="rpmH"
                     /locus_tag="ACL3R8_000940"
     CDS             complement(45742..45876)
                     /gene="rpmH"
                     /locus_tag="ACL3R8_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR1313842.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(46021..47235)
                     /locus_tag="ACL3R8_000941"
     CDS             complement(46021..47235)
                     /locus_tag="ACL3R8_000941"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1313843.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(47391..47684)
                     /locus_tag="ACL3R8_000942"
     CDS             complement(47391..47684)
                     /locus_tag="ACL3R8_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313844.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            47846..48298
                     /locus_tag="ACL3R8_000943"
     CDS             47846..48298
                     /locus_tag="ACL3R8_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR1313845.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(48333..49721)
                     /locus_tag="ACL3R8_000944"
     CDS             complement(48333..49721)
                     /locus_tag="ACL3R8_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR1313846.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            49787..50749
                     /locus_tag="ACL3R8_000945"
     CDS             49787..50749
                     /locus_tag="ACL3R8_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR1313847.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        14565 a        11558 c         9635 g        15063 t
ORIGIN      
        1 ttcatatctt atttcaagct actatatata atctaaaaac ctgaatcaaa aatcgaaaaa
       61 gtagcggatt tctccactgc tttaacagct tattcttcaa tttcgatttc aagttcatcg
      121 cctaagtcaa gcgtaacttc ttcattcact gcttcttctt tctttggctc atcttttttg
      181 ttttcagtat cttgttctga aacttcttct ccatcaatca agccaaattt agaacggact
      241 tgcttatcaa tttcatcaaa gatttctggg tgctctgcca agtatttctt agcattctca
      301 gaaccttgcc caattttttc atctttgtaa gaataccaag cccctgcttt tttgataata
      361 tccaaatcgc ttgcaatctt caaaagctca ccagtcttag aaattccttc tccgtacata
      421 atttcaacta cggcttcctt aaacggtgga gctaccttat tttttacaac cttaatctta
      481 gtttctttac cgacattggt ttctttttgg tcaccagttc ccttaatttg tgtattacca
      541 cgaacatcca agcggactga agcatagaat ttcaaagcac gtccgcccgg tgttgtttct
      601 ggatttccaa acatcactcc aactttttca cgcaattggt tgataaaaat ggcaattgtt
      661 ttggttttat tgatagaggc gccaagttta cgcatggcct ggctcatcat acgagcctgc
      721 aaaccaacat ggctatctcc gatatctcca tcaatttccg cacgaggaac aagggcagca
      781 actgagtcga ctacgacaag atcaactgca cctgagtcaa tcaattttcc cgcaatctca
      841 agaccttgct ctcctgagtc tggttgagac aagagcaatt cgtcaatatt gacaccaagg
      901 gccgcagcat aagctggatc aagggcatgt tccgcatcga taaaggcagc aatcccacct
      961 tctttttgcg cttgtgcaac tgcatgaagg gcaaccgttg tcttaccaga tgactctggg
     1021 ccatagattt cgatgatacg tcccttagga taaccacctg agccaagggc aatgtcaaga
     1081 gctaaagaac ctgagctcat cacttgcacc ttttgctccg cacgttcacc caaacgcatg
     1141 attgatcctt taccaaagtc tttctcaatc aatttaagag cgtcattcaa ggccttttca
     1201 cgttctgccc caaatttttt tgaaatttct tctaattttt ttggtttttt cgccattcta
     1261 ttctcctaca ttctaatgat cctcagacct atctactatt atatcaaaag ttagtcactt
     1321 aataaagcct tgcgaactag gttaaagaca tgcataaccg caatgtgacg tacatctgct
     1381 cggcttctgc ctccaatatt aaccttgata acctcagttc cttgatcttg cgccaagcct
     1441 atgaagactg tcccaactgg gtttccttct aggctatctg gtcctgccac tccagtcaaa
     1501 ctaattccaa aatcagactg ggtcttgctt cgtgcctgct cagccatctt ctgagctgta
     1561 aattcagaca ccacaccatg ttcttccaaa ttcttggcag gaatatccaa catccttgat
     1621 ttttcctcca agctataggt cacaaaaccg cccttaaata tacttgaaac tccagaaaaa
     1681 ttcgccacgg tagcttggaa aagacctgcc gtcaaactct ctgcagccgc gatggttttc
     1741 ccttgccttt tcagttcttc taccacaatg ctggctaaac tagtttcttc cccataacca
     1801 tagcaaaagt ctcgtaaaga aattccttcg aaagtctggc agtccaagat ttgattttcc
     1861 aagatatcca gcgcttgatt cgcctcttct tgactgctag cctttgttga cagacgtaga
     1921 gtgacttctc ctgtcttggc ataaggggcc aaggtaggat cgatctgatt atcaattaaa
     1981 tcagccaaaa tcgtaaccaa ctggctctcg ccaatcccaa agaaacgaag aactcgggaa
     2041 tacagcttgc tccctgtcat caacttgggt agaagttggt ttaagaccat gggtttcaat
     2101 tcacttggcg gacctggaag gacgacatag gtcactccgt ctacttctaa ttttcctcca
     2161 acagccagtc ctgtttcgtt tggcagtgga atcgctcctt ctacaatttg agcttgtctt
     2221 tcgttattcg gtgttcgggc atagtctggt cgcagggtaa aaaagatatc caacttctcc
     2281 tgagcctgag gatcaaagac taatgctttc cctaaaaatt tagctagggt ttgtttggtt
     2341 aggtcgtcct cagttggccc caaaccgcct gtcaaaatca ccagactgct acgttgactg
     2401 gcaatctcaa gcaaagacaa gagacgaact tcattgtctc ctacagccgt ctgaaaatat
     2461 acatctaccc caatctcagc tagtttttcc gacaaaaact gggcattggt gttgacaatc
     2521 tgccctgtca aaatctctgt tccaacagca atgatttctg ctttcatgtt tcctcctacc
     2581 tatctattcg tatttttttg aaaaaatcgc aggaattttc ctacgattga tttttttatt
     2641 tgtatcaaaa gttaattatc ttcatcacca acaggtgctc tgccaaataa atcttcaaat
     2701 aaaaccgcat tggtttcaag ctgagtaact tcttcttgtc ccaaagaacg tcggagtaga
     2761 ttttgcattt ccaacatatg tgctctcgaa acaatctggt aagaaacacc ttgaagtatc
     2821 tctccttcac cctgcaactg ctgagtttca atggttttaa atgaatcttt atagcctagc
     2881 aagttaggga tactttttgc agacaaatca atattggtct gcatattgtc actcaaagct
     2941 tttagaatct cttgataatg accaatgcta tttaaactga gagctttttc catgactttt
     3001 tgaataactt cacgttgacg tttttgacga ccataatccc cctcaggatc ttggtaacgc
     3061 attcgtgcat agactagggc ttcttctccc ccaatatgtt gctccccaac accgatagaa
     3121 atagtattaa attcttcttg gtcactgata gaaattggga aacctaggat attattgact
     3181 gtaatacctc ctactgcatc cactagtttt tgcaatcctc tcatattgac catcacatag
     3241 cgatcaatat ggatattcat cattttttga atggtttcta tagcaagctc tgctccacca
     3301 tctgcatatg ctgagttcag tttcgcttca tgagcctgac cattccctga ttcaatgcgc
     3361 gtcagaatat cccgctctaa actcatcatt gttgtttttt tcgttttagg attcactgtc
     3421 atcaagatca tgctatcact tctaccgacc caagtttcag ttcgttcaac atttccggtg
     3481 tccactccca ttaacagaat ggttagaggt tcagtcgctt caataacctt ggtttcttcg
     3541 ccgatttttt tataggtttt agctaaggtt tctgtccctt gttgataaat agtataagca
     3601 aaaacaccta ctcctactac agttacagaa agtaaagcta gcaccattcc aataattttt
     3661 ttaaccatat ttctactaac ctatcagttt acccatcaag taaacatcga taaatttccc
     3721 ttcttctata tatgccccac gctcttggct accttcaatg acaaagccat gcttttgata
     3781 aagatggact gctgcttgat tacgagtttg gacagtcagt tggagacgac gcagaatgcc
     3841 acttgcttgt gcccactcta tcgcttcttc tagcaacaaa cttcccaagc cattattcca
     3901 atatcttttt ccaatcacaa tgaagagatc tccaatatga cggactctct tacgctggtc
     3961 agctgtaata tttacaatac cagcaatttt gccatttaag aatgcaagta aggttatctg
     4021 attgtccgaa ctagcttgct tgttgaggaa tatttccatc tcctcactag tcaagagaat
     4081 accatctccg tctaggctgg taaagtctgt ctccaaactc acacgattta aaaaggccac
     4141 taattcagct gcatctttgg gctctgcttc cctaatgagc aattcatact ccatattgaa
     4201 gctcctctaa caatttctca gcacgcaaac cctttgcctg aaaatttaaa cggcgtccat
     4261 ctgcttcttt tagaatttcc aattctaaat aagcatctgg caaggcatct cctaagagat
     4321 ttccccactc aataacagtc acgccaccac caaagataaa ctcatccaag tcgatagaat
     4381 cagcatctcc ttcaatacga taaacatcta ggtgataaag tggaagtcga ccttcatact
     4441 ctctcacgat agtataggtg ggacttttaa tcatttgaga aatctgtaat ccttttgcaa
     4501 gtcctttagt aaaggtcgtt ttacctgcac ccagttctcc agttaagatt aaaacatcat
     4561 tctttgctaa tagatggccc aaactctccc ctaaggcttg caactcttct tcattttttg
     4621 tgtacatact cttattatac caaaaacttt tcttttgtgt ctattttcct actaaactta
     4681 tcatcataac atccataaaa aacaggcttt ctctaaaaga aaatgagcgt aacaatgacc
     4741 aatacaagat ctcggaaaat atgaccataa aaggaaactt ccttcttaac cgaatttggg
     4801 acaagatagg ctgcaaaaaa caagcccagt ccaatataaa tcagaagtga gacaatggtc
     4861 attggatttc ttaagaaaag aagtgttgct aaaatagtca ccaacactgt cttttttctg
     4921 tctagcatag caagaaaatc gcgcacgtat tttttcaagg gtaaaaaaat cagcaaatct
     4981 agcccaaata ggaaaaagaa ggatggcaat aaaaagtcaa ctaattcttg ctgcagcgta
     5041 tttttgatga acaagttatc tgacaaaaca agaacagctc ctaacaaatt aattaagagt
     5101 aacatactgt aaaaaagctt caccgacttc ttactggcta ggacactatg gacttcttgc
     5161 ttacgggtat aaagataatt tactccagca cagattcctg aaacgaaaac catgcttccg
     5221 atgaaaaaag ctgtactttg tttaaaggac aagatgcatt ccttccatag gaaacagcta
     5281 ctcaaactga tttgaattaa agctaacaaa aataagattc tcattgattt catcttctct
     5341 ctcccttcct accaatcatt atactaggag aaaagagaga actgtttcta atcttctcaa
     5401 atgtctcttt aagacgctaa acaaacacta gagactaata ctcaatgaaa atcaaagatc
     5461 aaactaggta gctagccaca ggttgctcaa aacagtgttt tgagattgca gatagagctg
     5521 acgtgatttg aagagatttt cgaagaatat agatttgaaa tcatgaaaat ccgtcaaacg
     5581 ggtggttgtt ttgtctcgca cctcacggag cgagacggac tcagagtcac ataattataa
     5641 ggctgatagt attaatctaa ctatcagcct tacaggttat ttaacgtttc agaaaaacta
     5701 taatgtcaag attaactaaa cagtatctag ttccttcaaa taattttcta tcttcatcag
     5761 cattaaagga ttgttataaa tcttgcatag ctctcttgct tctatataat aatttttgac
     5821 ttgttctctg tctagaaatt tggctccagc atttcctaca agaataagta gaggagccaa
     5881 ttggtagctt gtctgtcttt gtttacagag ttcaatcgtt tcaagagctt cttggatggc
     5941 ttcattatat ttttcctttg atactaggta gtgagcgtag ttgtaacgaa ctctgatgta
     6001 gccaaataaa aactcttgat ggtccaaatt ttttgtctga tacaactcta ttaaatgaga
     6061 gtagtttgcc tcatattctt gttcacgacc cactaaggaa tagaaattag atagagtatt
     6121 caacgccttt aaataaatca gagtatttga agagactttt aataatatat tttccaatga
     6181 agaaattgcc tcacacttac tgtcatattg atagaagtca ataatagctt taatccattc
     6241 aaggtaagtt cggtcttcta gtgttagaaa agtacttcgt tcaatctcta ttctataaat
     6301 atattccaaa tcgtcataat ttctatcgtc taatagtcga gcagacaatt gcttgaaatt
     6361 agagaggtta gatttaattt caatttgttc attaaaaaaa taatctaatg gtacttcaag
     6421 tcgttgagag agtttgaaca aaaggtctgc ggagggaatg aaatgccctc tctcaatttt
     6481 actaatctgg ctttgttcac aaattccttc tgcaagagtt tgttgggaga gtctcaactc
     6541 ttttcttttc aatctgaatt tctctgcgag tgtattcatt aaagataata aaccttccta
     6601 tttgcttaat tgcattataa aatttttagt tcaaaatagc aagttaaagg aataaataat
     6661 tctttatggt aataaactaa aaaaagtcaa aaattacata aaaatgcttg accgaataat
     6721 atatatatat taaaataaaa acaaggaaaa agaaaagggt ttcacgaatg aagaaaaatc
     6781 gtggaattca aaaattagct atattagtat tactaggtgt ttttatgttt agtaacacaa
     6841 ttccttacca acagtttatt cagaagaata gacaattgga gattcgagtg caatcacaaa
     6901 agaagtccaa tggtcttgat gttgggaagg ctgattgatt tcgtattact ttaaaattca
     6961 actatttaga gaaaggtatt ctgatgagag cttgtaacaa taccagatag atataagaat
     7021 ggagatgttt gataaaatgc tttcatagct aaccaactgt tgaaaattat gagttacaaa
     7081 atctaaagta tttaagattg gtttataaaa ttaggtctct gcctgtagaa aggaacgtgc
     7141 agttagaaag gaggaaaaaa taggatacta taattcagac tgagatttct aattaaaata
     7201 tgtagttgca tttcgctcat tttcataata tttcattcag aggagtaata atatgttaaa
     7261 atttagattt gatgcgggat ggtaaagaat aattgaagaa gattctttta tcaatagttt
     7321 agtaagcttg ttagtttata gagggcaggg gtatttctgc cctctgtttt agaataagga
     7381 atgcactatg aaaaaattat ttatactcat atccaacctg cttgctagtt tgttctttgt
     7441 ttgggtattt accatttgga ctgatacata tgtctcccat tattacccca acgttgttgt
     7501 acgtgattct tcccctgaaa caacttttca gcatgttgct acacgcttgg aaaaactagc
     7561 agaagaaaca gatagcttta ttgcgattca acaccaagat cctaactcag aaggtactac
     7621 agttttttct tatacgacct ttggggacgg aaagttgcct gatgggcttc aggaaaaaaa
     7681 tctagaagat gctcaaagta gtagtgttga aacaaactat tttgtattcg atggacacct
     7741 agatattcac ttgctaaggg aagagctaag tcaacttggc ttgactaaca tgcacctgac
     7801 aattccatct aaactatcta cgttaatggc tatctttagt aacggatttc agttaatcag
     7861 tctattgatt ttcatcttaa cctttgtagc actgacttta attagtcaaa ttagccaatt
     7921 acggtcatcg ggcattcgcc tcatttcagg agagaaacgg tggtccattt tccttagacc
     7981 agttggtgag gatttgaaag cgatagctgt tggtttcagt ttagctggcg tgctcgccat
     8041 tcttatgcaa aaaattctgt cgcttccaac gcaatcccta atgaccacag gagaaggctt
     8101 gctcagttat aatctcatct tgttgtcgat ctccctgttt ttcactcaac tcttcgcagt
     8161 tgggataaaa aagatacacc tgatgcagat tataaaaggg caagtgcctg tcagaggaat
     8221 cattagtttg attttaatcg gtcaactatt agcgattatt attgtaacgc tgggaatagg
     8281 gagtagctta aagtattccc aagcctggca acagcatcgg attggacaag aggtttggag
     8341 tcaggaaagg caactgatta ccctatcaat cagccgtgaa ggaacgagtc ctggttttga
     8401 tgaacaagct caaaggaaac tcagaacttg gtatcaattg atggatctgg ctgtttcaga
     8461 acaaaaggct ttcttatcta gacaccagtt aattgaccgt actttgcaaa atggcatggc
     8521 ttcctccaaa aacttgataa cctctacaga atggcacgat tacaacccga atggcaatgt
     8581 ccttatcgtc acaccgcaat acttggagcg tcaaaacatt cctgtagata caactattga
     8641 gcaaaagatg aatcaccttg atgtagggga gtttgtctta ttgctgcctg aacacctccg
     8701 ttcagaggaa gaacattata aatctgtttt tgaagacgac ttaaccagtc gcatgtctag
     8761 tcaagatgaa cgacagcaaa tgactgctac ggtaggttat ttagaatcag gtcaggatcg
     8821 ttttgtgtat aatacgaccc ctatttctta ccagcagttt ttgaaagatc caatcatcat
     8881 tgttataaca ccccaatcaa ctggtccaca gtccattttg ttttggatag acgcagtaca
     8941 gaactacgtt ctctttaatc aattgtctga tgcccaggag cttatccaga gacaaggcat
     9001 tgaaaattgg gtctcagaaa tgcaaacagg ttaccacaac tacatcacat tattggataa
     9061 tatccagagg gaacgttggg taatgctagc aggagctgtg cttgggattg caacttcaat
     9121 cttgttgttt aacactatga ataggctcta ctttgaagaa tttagacgtg ccatttttat
     9181 caaacgcatt gcaggtctca ggttcttaga aatccatcgc acttatctct ttgctcaact
     9241 gggtgtgttt ttactgggat ttgttgcgag tgtatttctt caggtagaga taggagttgc
     9301 tttcttagtc ttgttactct ttactggtct atctctttta cagttacatg tccaaatgca
     9361 gaaagaaaac aagatgtcca ttcttgtttt gaagggaggt taatatgatt gaacttaaac
     9421 aggtgagtaa atcttttgga gaacgagagt tattttcgaa tctttcaatg acatttgagg
     9481 ctggaaaagt ctatgcctta attggttcaa gtggtagcgg aaaaacaacc ttgatgaaca
     9541 tgattgggaa attagaacct tatgatggga cgatttttta ccgaggtaaa gacttggcca
     9601 attataaatc gagtgatttt ttccgtcacg aattgggcta cctcttccag aactttggct
     9661 taattgaaaa ccaaagtatt gaagaaaacc ttaagctagg tctcattggt caaaagttga
     9721 gtcggtcgga acagcggttg aggcagaagc aggctttaga acaggtcggc ctggcttatc
     9781 ttgacctaga taagcgcatc tttgagttat cgggcggaga atcgcaacgg gttgccttgg
     9841 caaaaattat cttaaagaat ccacccttta ttctggcaga tgagccaaca gcttcaatag
     9901 acccagcaac ctctcagttg attatggaga ttttgctatc tcttcgagat gataataggc
     9961 taatcattat cgcaacacat aatccggcaa tttgggagat ggctgatgaa gtgttcacga
    10021 tggatcatct gaaataaaaa tccttgtttt taattgcacg atgagttact gaaatattat
    10081 catgaatcaa gaattggagt taatttagaa ttgtacttta ttaatattga ggtaactttt
    10141 tcttgataaa ggaagaaata atggagagga agttagaatg aaaaaattcg acaattatat
    10201 tattgagaag ccttgcgatt ctaattcaga taaactgcaa aaaatcttaa taattgaaag
    10261 tttggtagat gatattttgc aattttctct cagaatcaat aatagtgtag gagagatttt
    10321 cctcctacaa ccgttttaaa agaaaactat ctttattcca tgttattttg aggaagatat
    10381 tgtgaaagtc aaagatgatg ataaagttga gtggaatttg ttagaatttc aaaaatttag
    10441 agcatttttg gcttagtaat ctgtgttgaa ggctcaaaac ctatggtaaa aaagtcgctt
    10501 tgaaaacgta ttgcctccaa agatttagtt aaataatgat ttaacacaaa aagaaattat
    10561 tgaagttctg gaaagatgtt gtttcagtat tgagaaaagg tgggaaaaac ttgcgatttt
    10621 cacagagaaa ggaagaaaaa gtatagaaat atagtcaatt gaaacaagaa caggataaaa
    10681 gaaccttttg tgccatattt ttctcctttc gctttacaat tggcttgaac acctttattg
    10741 tatcgcgttt ggagtttttt tggtataacc ttcgacgcgc acccgcatag cgggtgtttt
    10801 tttgtctcgc acctaacgga gcgagacgaa ctaatagtca cttaatcaaa aaacgcacca
    10861 tatcaaaaac taaaaagttt gatatcatgc gtcatgtctt aaactaattg actatacttt
    10921 ctattcaaat gagcttttaa ccaattgatt gagccaatcc actcttaaaa ccaaagagca
    10981 atttctcgct tagctgactc ttctgaatct gaaccatgta caacattttg gataacctca
    11041 ttttctccag cagcttttgc aaagtcacct cgaatagtgc ctggtaaagc ttcttctgga
    11101 cgagttgcac ccatcatggt ccgccaagtt tcgattactt tgggaccaga aatgacaccc
    11161 acaagaactg gacctgaagt catgaattca cgaatcggta ggtaaaaact ctgaccaacc
    11221 aagtcctgat agtgctggtc aatcaactct tctgaaacct gtgaacgaaa ctccaatttt
    11281 tcgattgtaa atccacgttg ttcgatgcgc tttaacactt cacccactag ccctcttttt
    11341 acaccatctg gtttgatgat aaagaatgtt tgttccatac ccgtctcctt tgtcagcttc
    11401 tttcttttat tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga
    11461 gagaacccga gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg
    11521 cagtatccac aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa
    11581 ggtattcttc ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac
    11641 cagctgggat gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct
    11701 taccacggat agctgcgtca gtaaggacac gagttgtttc ttggaaggaa gctgctgaca
    11761 agaaactgtt tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg
    11821 ctggaactcc acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca
    11881 tgagggtacc catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca
    11941 tttgacgaac cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa
    12001 ctttttgtac ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga
    12061 gacgttttgg ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa
    12121 cttcgacacg catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct
    12181 taacaaagac tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt
    12241 taacctctgt gataaccgct tcccctttag gattacgggc ttcaaagatt tcttggacac
    12301 gaggaagacc ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca
    12361 ttgtaagctg tgtaccaggt tccccgatag attgggcagc aattgtacca actgcttcac
    12421 caacttcaac cgcatcacca gtcgccaagt ttataccgta acagtgacgg cagacaccgt
    12481 gacgagtgtt acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa
    12541 tttcacgcgc cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt
    12601 ctggatgttt aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga
    12661 tcatctcttt tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt
    12721 cctcacggat gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt
    12781 cggctgtctt aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca
    12841 tttccaatac cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc
    12901 cattcggagc agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac
    12961 cacgggctcc agagtccatc atcataacga ttgggttctt aggatcttgg ttagcaatca
    13021 agcgtttctc aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct
    13081 cgtcgtctgt gatcatacca cgacggaatt gtttggtgat ttgctcgaca cgtttgtgtg
    13141 attcttcaat gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca
    13201 atcctgcaag agttgagtgg tggtaaccga gattcttcat gcggtcaagt agggcagaag
    13261 tttctgtcgt acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct
    13321 tgaatggagg gttgagctca agattgctga tagcttcctt gatatctcca ccaagtggca
    13381 agaagtattt agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg
    13441 gtagcccctc tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct
    13501 tatgtctttg ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg
    13561 agtggaggtg aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga
    13621 ccattccttc accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca
    13681 tgtcctgaga tggagtaact accggtttcc catctttcgg attcaagatg tgctcagcag
    13741 ctagcatgag gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca
    13801 tttggtcccc gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag
    13861 ccttaccatc aatcaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg
    13921 cgcggttcaa aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct
    13981 catctccgcg ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa
    14041 cgatttcacg catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac
    14101 attggtacat cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac
    14161 gtttaccgag caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg
    14221 atttcaatgg acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca
    14281 aagcgtcaac tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat
    14341 ttaactcaag caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat
    14401 tcaagtcaga tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg
    14461 ggataaccgg aagaatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg
    14521 catccaaaac atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca
    14581 attcttcttt gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga
    14641 tggcttccgc acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc
    14701 ggtattcgcg ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca
    14761 ccacataagc cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca
    14821 agcccatacg gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt
    14881 cgatatgtcc catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt
    14941 cacaaacaat tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt
    15001 ttgtaggacc aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat
    15061 aattgattgt ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag
    15121 aagctagggt gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt
    15181 ctattctaag tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt
    15241 tgctttctca gcttcttcag cttcaaaggc tgctttagcc tcttgagctg ctttttcgcg
    15301 ggctttttca aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg
    15361 aagttccact tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa
    15421 ttctttgaca agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt
    15481 tgtaatagct tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat
    15541 ttcttgaagg acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa
    15601 acgttgtcca ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg
    15661 tccgactgaa cgcgcatgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat
    15721 gactccaaca gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt
    15781 cttggcatcg ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc
    15841 tccatcaaag actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg
    15901 aagctccata acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat
    15961 gtcgactgga gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac
    16021 aacccctttg tttccgtgac gtccggccat tttatctccg accttaatct tacgtttttg
    16081 agcgatgtaa acacgaacca acatgttaac acctgattgc aactcatctc catttacacg
    16141 tgtaaagatc ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt
    16201 atcacgcact tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga
    16261 aagatctttc tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc
    16321 agcaccaata cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt
    16381 tggaatttcg cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta
    16441 ttcttcaagg tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac
    16501 ggcatcctcg aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag
    16561 cgccatttct ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac
    16621 atcaccaact tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa
    16681 tttttggatg tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc
    16741 atctgcgtaa gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc
    16801 tgcttggtat tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc
    16861 ctgacgttgc atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg
    16921 aatacatgct gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat
    16981 attagctgga tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa
    17041 ggttccatct tcattcagac tagagttagc ctgagctaca gtatattcat cttcttcatc
    17101 agctgtcaac caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta
    17161 tggtgtttga acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa
    17221 accgatgtta ggtccttcag gtgtctcgat tggacacata cgaccatagt gagtgtagtg
    17281 cacgtcacgt acttcatatc cagcacggtc acgagtcaaa ccaccaggtc ctaaggctga
    17341 caaacggcgt ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa
    17401 ctgtgatgaa ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg
    17461 ttgtggtgtc aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat
    17521 acgagaaagt cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg
    17581 atttccaagg tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta
    17641 gctcatctca gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc
    17701 attaccaatg atcgttacga cgcgatctgg atcagttgga gcaataacct tgaatttttg
    17761 aagaacaaca ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa
    17821 gtcgccatcc aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc
    17881 ttctaccaag atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag
    17941 caaacgtgtt ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc
    18001 atagcgacgt gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagccgtctt
    18061 aggctcacct ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc
    18121 cattggattc ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa
    18181 aatatcaaag atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg
    18241 aatcttacga gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc
    18301 caaccaagct ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc
    18361 tactttgtcg ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc
    18421 accaccattg atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac
    18481 ttcttgggtc ttgatttcgc ctgtttcttt attgatcaag cggaaggtta caaaaattgg
    18541 tgctgagtag ctagcatcgt gaatacgagc ttcttctagc gtgtattttg gttccttgat
    18601 ttcatatcca acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc
    18661 ttcaaacact tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc
    18721 aatcaaattt ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg
    18781 tttcccgtat tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag
    18841 ccttgtcaat caggcttttc taatcgccat atggttgtaa accccttatc accgtgtcct
    18901 cttgacgaat tttcagaatc tttaagcctc tgttacaaat gctcaaaatc ttgaaaaaaa
    18961 gcacaaaaag agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc
    19021 tggacaatat ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc
    19081 tagatttttc aaggggattc agtaggtttt tggtaatttt tttcccatag aaaacttggc
    19141 atcacattcg aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt
    19201 ttcaaggtat aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca
    19261 aaagcttgat cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt
    19321 caaatgaaca gaaagcccaa tttgaagggc tttttttatt ttccctcgaa taaatacgta
    19381 taactttaaa aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct
    19441 tttgaaatca attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct
    19501 gtttcttctt ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc
    19561 ttcactttat cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt
    19621 ttctcagtcg ttggaatggt tcccactcct gtcaaataat aaccagcgat ggtatcaacg
    19681 tcatcacttt ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct
    19741 tgaacaatgt aggtatcctc gccaatctga tgaacatcta ttgctgcttt atccgtttca
    19801 tcatcaattt caccaacaat ttcctctaag aggtcttcca aagtcactaa accagccata
    19861 ccaccgtatt catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc
    19921 aagtcatcca caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa
    19981 acaatattgt caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt
    20041 ccaattacat tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa
    20101 atactttgga taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga
    20161 ggaaccataa cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca
    20221 atctcatcag catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg
    20281 gtcatctttt catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc
    20341 gaagcagcta aaagccaaac aaaaggactg actagttttc cgatcccaat gataaccggc
    20401 gctgtacgaa ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc
    20461 ccaaaaacga tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt
    20521 gctgtttcgc cattcccaag ccaagaggca atcacacgtc ctagagtatc agttaaactc
    20581 gcccctgata agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta
    20641 ggattttcta gtaccttcag caggcgaatg tagcgtctgt ctccttcttc cgccttttgt
    20701 tcaactcggg cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt
    20761 aataccgtca agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct
    20821 tccatagttc ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca
    20881 atacatatta tttttttctt agcgtaactt ccatctctct cccaaaactg gaagttagtc
    20941 taagacggat ttccactgat ttcacgcgtt tttctcatac taaaagctag gttgtgggaa
    21001 actggaagtt agttttagaa gttactattt tttcttagta cctgttctag ccctgcttaa
    21061 actagtaaaa agaactccta catccataag tgacatagga gtttaggctt atcttttact
    21121 gagttacagt tacttctcca gttcggtaat ccagttgaag tcccttttga acattgggaa
    21181 ctagaacatt gaattccaat tctccatccg aagacttggc ttcaatctgt gaagctgagg
    21241 gaactaaatc ctcgtttgaa gcgtagtaaa gggttacacg gtaacggaca cgcttgtttt
    21301 ggtccaaggc tttacgcacc ttgctttcat agtagttttg accagtcgaa tactcggctt
    21361 gtgcctgatt tgcccaggct gtctgaacag caatgttttt aggattgctt gttgaggcat
    21421 caaaaccatc caaaccaccg attaaggcat agcctaacaa atgacctcta tcgactgcat
    21481 gggtataaga gccctttaga ttcttgacct gatgccaacc tggaggagtc caagaagttg
    21541 aaccattccc agtttcttta cgattcttgt actgacgagt ggccttagac aagagggcat
    21601 tagctacggt tggaacagtt tccttgccca ctgtctttgt tttattgtca gcgtagggct
    21661 tacttgaaac cttggcatct agatttgttt tattaccatt gacgataaaa gcacctgagc
    21721 cattccactc cagactcccc tttatttgac tcttgactgc gtctgttaag acactctctg
    21781 ccaatgcttg actaggagct tcaggcgctt gttttttctg actaagcttg gttttaggac
    21841 tattaggtgc cgactgcatc tgcttgatat aatagctccc tgtagacaaa agcaataaca
    21901 ctagcagtcc gattagtgtc tgtcttgttt ttttgttcat atttctcctt atctttagaa
    21961 aaaggctggt tctccagcct aatttcctgt aaatttatga atcaattcct gccattttgc
    22021 tggagacagg atagcccatg gatcttgacc cttgcccaag attccataac ctaccattaa
    22081 accgattcct agagccagag tacctaaaat cagtactatg atgactaaaa gtaaacgctt
    22141 gactacgtag cttgatttct tattcatctt catcacttgc ctcaatccgc tgaatcttag
    22201 cacctagctg cgccaacttc tcatggaaac cgtagtaacc tctatccaag tgaaccaatt
    22261 taccgaccac agtttctccc tgtgctacca aacctgtcaa aatcaaggct gcactggcac
    22321 gaaggtcagt tgaaagaact tctgctccct gcaaaggctg tccaccaaca atacgagctg
    22381 tatcacggat aatctcagaa tgcaagccca tgcggcgcat ctcttctagg tgttggaaac
    22441 gattttcgaa aactgtctcc accatggttg attcgccttt tgcaactgtc atcaaggctg
    22501 taaattgagc ctgcatatct gttggaaatc ctgggtgggg caaggttttc acatgaacag
    22561 cttttagatt ttctagttga gaacgaacac gaattccttc gtcttcttca attacttcaa
    22621 cacccatttc aagtaacttg gcaatcaagg gacggttgtg ctcccagaca gcgtctcgaa
    22681 tcaagacatc accaccagtc atggcagcag ctaccataaa ggttcctgct tcgatacggt
    22741 cttggactac attgtgagtc gtaccatgaa gtttctcaac accagtaatg gttatagtct
    22801 ctgtaccagc acctttgacc ttggctccca tttcattaag gagaatggct aagtcaacaa
    22861 tctcaggctc acgcgcagca ttctcaatca ctgtcacccc atcagccaga gtcgctgcca
    22921 tcatcaagtt ctgcgttgca ccaacacttg gaaagtccat atagatatga gcgccatgca
    22981 agcgttctgc cttggcttcg atgtaaccag ctgtctgact aatcttaacc cccatagctt
    23041 ccagaccttt caaatgaaga tcaataggac ggctaccaat cgtacaacca cctggcatgg
    23101 ataccttggc atgacccaca cgggcaagga ttggccctaa tacaacgatg gaggcgcgca
    23161 tcttgctgac atacttgtaa ggggcttcct cagtgatgtc gccagtagca tccaccttga
    23221 caagatgagc ttcctcatca aagtcaacct tggcattcaa accaccaact acctgattca
    23281 taataaagac atccgacaaa atcggaacat tctgcaagac ggtctttcct tcacttgcta
    23341 gaatagtcgc tgccaacaag ggtaagactg cattttttgc tccctcgatc gtcacgcttc
    23401 ctaccagacg attatcgcca ccttgaacca caattttatc catactcgtt tcctttactc
    23461 ttgatttcat aataatcctc taagcgcttc ttgccacaaa tgatacaggc taataaagaa
    23521 agaactcagg atgtagccta tgacaatgct aaaaaaggct actaataaac gaacttttct
    23581 tgtattatca tctgtcactt ttaaaacctt ctcccatcta acaagatcct ttaaaaggta
    23641 aaaactcaca taaataaaga acatatgact acttagagtg aataataatt gaaccatttg
    23701 actattatac catcttctct gtttgtgcgc tagtttggaa acttcactca aaaattaggg
    23761 attgtttttc aagtaatcaa tcgcatcttg tagggtttta acgggcacga ttttcatatc
    23821 cgtcttgatt gttttagccg cttctagggc tgtttggtag ttgtttttcg cgtccggatg
    23881 cgccttttgt tcttcttcgc taacagggtt atcaggagca aagaaaatag cagcacctgc
    23941 cctagccgaa gctacaacct tcttatcaat acctccaatg tctcccacat taccatcgcg
    24001 gtcaatggta cctgtaccgg caacaatacg accattacga agatctgggt gagctatttg
    24061 agtatagata gctagactaa acatgagacc agcacttgga ccgccaatac cagctgttga
    24121 aaagctaatt gggacattgc tgattacctc tgtacggtca atcaagccga ttccaattcc
    24181 atttttgcca ttttccaagg tgatgatttt tccttctgca gacttggttt gcccatcctc
    24241 ttcataggtg accttgacgg aatcccctaa tttttgagaa ctgacgtaat caatcaagtc
    24301 tttggaacta tcaaaggtct gatcattgac tgctgtgact gtatcagaga tattgagaat
    24361 ccctttaaag gttgaattat ccgtcacatt caaaacataa actccaaagt acttgagttc
    24421 gatatcctta ccagctgttt ttagtccttg atacttggcc atattttgcg atgtttgcat
    24481 gtagaattga ttgattcgca taaattcaac atcggaagaa ccacctgtag tctcctgagc
    24541 actacgaata tctgtaaaag gtgtcaacca agcataaatc atatgagcta aagtggcatg
    24601 ttgaacacca accgtaacga attgataggc accagcttcc ttatcttctg tgtcatttac
    24661 tttaaggact tggcgaatat cttccgaacc acctggaacc tctatataat aaggcaaggg
    24721 cactacaaat gccaagaaag tcacaatcaa ggccgcaatg acgtataagg gccatctaat
    24781 cttttttttc atttcttatt tcctccaaaa tactctcggg aacatagcag gcaatatcct
    24841 gaccaaactt caaaagctct ctaacgcctg atgaactgat atagagatgt tcaggtcgac
    24901 tatgtaaata aatagtctct atatcagaag acagctgatg attgtagtaa tcaaaactgg
    24961 cttcatattg caaatccgac gcatttctca agcctcgcac taggcaagta gcccccagtc
    25021 tttttgcgac atcgaccacc aatttatcat gagaagacac gactttaaca tttcccaaat
    25081 gtttcacagc cttttctaac ccccgtttac gattttcaag agggagaaat ccttgtttgt
    25141 ggggattaaa aaaaataccc acataaagct tatcaaagag tctgctcgcc cgttcaatca
    25201 tatccagatg cccatttgtc atcggatcaa atgagcctgt gaataagcca atcttatctg
    25261 acatagactg tcaccttact aattccataa atcttttcct tccagatacc cagacaggca
    25321 atctcttctg gaagttcaac ggccttatcc gtctcgcaca caaccataac atcttcagaa
    25381 aaaagctctc tctcagccat tttttcaata tctgctacga tttgttcctt ggcataggga
    25441 gggtctaaga aaacgaggtc aaattcccca gatacctgtt ccaatgccct ctctgcatcc
    25501 atcttgagga gttgaaattt tccaacttcc ttggtcatct ggatattttc agccacgatg
    25561 gtctgagcct tacggtctcg ctccaccaaa acagcactgg acatgccacg cgatactgct
    25621 tcgatagata aaccaccact acctgcataa aggtccaaga ctcgtccccc ttcaaagtag
    25681 ggaccaatca tgttaaaaat ggctccccta accttatccg aagtaggtct tgtcgtcttg
    25741 ccttctagtg tcttgagggg acgtccccca tagattcctg atacgatttt catactgttt
    25801 attataccaa attatagaca aaaagagaaa gaaaaccgaa ccttgcggtt cgattctcta
    25861 caaaatattt tcgtaagtat cgcggacttc ttgaggccaa acacttgttt gcacttctcc
    25921 gatgtgtctc ttgcgaagta ggaacatggc catacgagat tgtccaattc ctccaccgat
    25981 tgtcaatggg aatagaccat tcaacaaaga cttgtgccat tccaattcca agcggtcttc
    26041 atcacctgta atttccacct gacgtctaag agtttcttca tctacacgaa ttcccataga
    26101 agacaactca aaggctccac ctaaagactc attccagaca agaatatcac catttagacc
    26161 cttgtagcca ttctcagact cgcttgtcca gtcatcatag tctggtgcac gtccatcgtg
    26221 cggtttacca tctggcaact cgccaccgat accaatcaaa aagacggctc caaattcttt
    26281 acaaatcgca ttttcacgtt ctttcggtgt caagtctggg tagcgttcta ccaattcttc
    26341 tgtatggata aaggtgattt gttttggcaa gatagactcg atgtcatagc gggcttcaac
    26401 agctagctca gtcaggcgaa tagccttata aatcttctca actgtttctt ttagataaac
    26461 gatgttacgc ttaccatttg ggataacctt ctcccagtcc cactggtcaa cataaacaga
    26521 gtgggttgca tccaaggaat cctcatctgg acgaagggct ttcatgtgga caaagagacc
    26581 ctctccttca ccaaagccaa aacgagccaa ggtgtggcgt ttccatttag caagtgagtg
    26641 caccacttca taagtagcat cagggatttg gagaaccttg accgatactg gattttccac
    26701 accagacagg ttgtcctgca ttccgtcacc gaccttactc aagataggac cttgaacttc
    26761 gacaacttct agcttatctt tcaaatactg ggtaaaagtg tttttgacaa aggaaatttc
    26821 ttcttgttga tggataaaac ttttcttcat agacaactcc tcaaaaattt aataaacgta
    26881 ttatacacct atttccaaga aaagaaaaga gaaaatttaa aaaaatcagt gtcactcaaa
    26941 acactgattt catagacctt ttagtcattg cgaccaaaga tacgtagaat acttaggaaa
    27001 agattgataa aatcaagata gatgctgaga gccattgaca ccacccagcc tgtcgctaca
    27061 cgaccttgtg attgttcata ggcgaggcga atcttttggt tatcccaagc aatcaaccct
    27121 gaaaaaacca aaaccatggc tacgctaatc atataatcaa agaagccact agccaagaaa
    27181 atattgacta ccatagcaat cagtaaacca atgagagctg ccatcattgc tcgaccaatc
    27241 ccactcaagt ctttcttggt aaagatacca actgccgcca tgacaaagaa gagaagggcg
    27301 ctcgatacaa aggcagataa aactgtaccc ggagtataga aagccaccac aaaactaagg
    27361 gtaaagccgt ttaaaacgga gtaaagtaaa aatactggaa gagcagctgg actatttctt
    27421 gaagccatgc tactggcaac gaaaaccaaa gccaactccg caaaagtagc aatggtcaac
    27481 cagagacgcc cctgcatcaa caagtaaacc aactgagact gaaagaccgt caacataagg
    27541 cctgatacca aagcagatag tccgattccc agaccaacaa aggcataaac cttagcgtaa
    27601 aattgattga gacctgcacg gtcatgtata atagtgtgat tcatcctttt ctccttttct
    27661 gtgaacatct ttccttgatt ataacaaaaa aagttaaaat tagcttaaat ggaagattaa
    27721 aataccggtt gcaactgcaa cattcaaact ctcggcctgc cccttcatgc taatatggac
    27781 caactggtct gcactttcag ccataagggg actaattcct tgaccctcat ttcccataac
    27841 tagtacaaaa ttttctatag aaggcagttc tctgtaatca acagaatctt tagatagggt
    27901 tgttgctagc actgggatag ctaccttttt agtttcgtca agaagcgctt gactagtcat
    27961 ccggtaaatg ggcagatgga aatgactacc ttgcatggaa cgtagggttt tgagactgta
    28021 gatgtctgcc gacttatctg aaacaatcac tcctgtaaaa cctgctgcat ccgcagttcg
    28081 aatgatagtt cctacattac caggatcttg cacatcttcc aaaaacaaga acttgccctg
    28141 actcaaatca gcttgtccta cttcttcttt ttgaaccacg gcaacaattc cctgtggagt
    28201 ctgagaatcc gccaaatcta gcaaaatatc ctctgaaatc cagacagttt gcggaaaagc
    28261 agctaactga tttcgataat tttctagggc aaagattttc tcaatcgtca ctccagcttg
    28321 gacagcttct tcaaacaagt gccagccttc aatcaaatag gcagacttgc ggtatttttt
    28381 ttggtgtaat ttcttggcat tttttaccac agaattggct tttgaggtta taatagtcat
    28441 agaaatatta taacacaatc aaaggggttt ggtatgcaaa aggttagaat gattgcccaa
    28501 ggtagggtgc agggagtcgg ctttcgttgg ggtgtttata gcctggccct tgaaatcggt
    28561 ggcatcacag gtcgggtatg gaataacgac gatggcacag tggaaatctt agcccaagca
    28621 gactcatctg ctatcatggc aaaatttatc caagaaatcc gaaaaggacc gacacctttt
    28681 tcaaaagtaa gctacttaga tgtcaaacta agcaactttc ctccctactc tgactttaaa
    28741 atcgcaaatt aggtctccag aactattgta tattttgtaa aaaaacagta gaatagaaag
    28801 gtataatttt taaagaagga ataaaaacag tgaaatctat taaacgtttt gcattctcgg
    28861 ctatgggagt ggctatgttg cttgtcttga ctggctgtgt caatgtcgat aaaaccacag
    28921 gtcagccaac aggatttatt tggaatacga tcggagcgcc tatggctgaa gccatcaagt
    28981 acttcgctac tgataaaggt ctaggctttg gtgtcgctat cattatcgta accattatcg
    29041 tacgcttgat tatcttacca cttggtatct accaatcatg gaaggcaacg cttcactctg
    29101 aaaagatgaa cgctctcaag catgtccttg agccacacca aacacgtctc aaagaagcaa
    29161 ctactcaaga agaaaaactc gaagcccaac aagccctctt tgccgctcaa aaagagcacg
    29221 gcatcagcat gtttggtggt gtaggatgtt tccctatcct ccttcaaatg cctttcttct
    29281 ctgctatcta ctttgctgcc caacatactg aaggggttgc tcaagcaagc tacctaggca
    29341 ttcctctagg ttctccaagt atgattttgg ttgcctgtgc tggtgtcctt tactatcttc
    29401 aatcgctcct ttcacttcac ggagtagaag atgaaatgca aagagaacaa atcaagaaaa
    29461 tgatttacat gagcccactc atgatcgtcg tcttctccct cttctcacca gctagtgtca
    29521 cactttactg ggttgtcggt ggtttcatga tgattctcca acagtttatc gtcaactata
    29581 tcgttcgtcc aaaacttcgc aaaaaagtcc gtgaagaact agccaagaac ccaccaaaag
    29641 caagtgcttt ctctaaacca agtggacgaa aagacgttac ccctgaacaa ccaactgcta
    29701 tcacaagcaa gaaaaaacac aaaaatcgca acgctggaaa acaacgttcg agataagaag
    29761 aaaaaggctt agctaatttg ctaagtcttt ttgcaaatca aaagcccgat gtttccatca
    29821 ggcttctttt ctatccatgt acacgtttca tataatcttg ataactttcg gtatccatga
    29881 gttttttagc gttcttgacg cgatctgctg ttggtggttt gactccttcg agggaatatg
    29941 gaattccaag ttcacgccac ttgaactcac ccatggtgtg ataaggtaga atttcaaact
    30001 tatcaacatt tttgagggtc ttgacgaact taccaagttc aatcaagtca tcatctctgt
    30061 ctgtcaatcc tggaactagc acgtggcgaa tccagacagg ttttccaata tctgatagat
    30121 actgggcaca agccaagata tttttattag tttggctagt gacaatcttg tgctgttctt
    30181 cgttgatttc cttgatatcc aaaagaacca agtcagtgac agccatgagt ttgtcaaact
    30241 tctcaaggta acgtggttta ttacggaaag gaagagcaca ggtatccaag gtacagtgga
    30301 ttccttgttc cttagccttg gtgaagagag caatcaggaa atcaatctgc aagagagctt
    30361 ctcctccact gactgtaatc ccacccttat ttccccagaa accacggtag cgcaaggcct
    30421 ctgtcaagac atcatctact gtccgttcac gtgacttatt ggactccata gcccaagtgt
    30481 ctgggttgtg gcaatactgg caacgcatgt gacagccctg caaaaagaca ataaagcgaa
    30541 taccaggccc atctactgac ccaaagcttt ctgtcgaatg caccattcct gtcacttgtc
    30601 cataatcaat tgtttcttca gacatatcgt taccttcctt gaaaacgttt tatagtttta
    30661 ttatatcacg acttgaagga aaaacaagat ttttgcctat tttttagaaa gcaatctgtt
    30721 tttcaatttc attttcaatc tattatcaga ttattcttca aaatcgaagc catataaggt
    30781 tgcaaaatag tcctcagggc gctctgcacg gcggatttga cgggctttac cttcttcggt
    30841 atagaggatt tccgcagaac gtaatttggc attatactgg tagcccattg aaaatccgtg
    30901 ggcacctgta tcatgaatta ccagcaaatc accgatttct gtatgaggca gttcgcgatt
    30961 cactgcaaat ttatcattgt tttcacagag tgaaccaacc acatctaccg cttcagctgg
    31021 tccatctgga tgggtcacgt tgctaatatg atggtaagct ccgtacatag ctggacgcat
    31081 gaggttgact gctgaggcat ccacacctag ataggtacgg taggtttcct tcttatgagt
    31141 cactcttgtg actagagcac cgtgaggtgc cagcataaaa cgacccaatt cggtgaaaat
    31201 cttgacctga ccaagacctg ctgacgtaag aacttcttca tacaccttac gaactccctc
    31261 accaatcaag gcgatatcgt tcggctcctg gtctggacga taattaacac caataccgcc
    31321 agaaagattg ataaagtcta gcgaaatgcc caacttttcc ttgatttcaa cagccagttc
    31381 aaagagctga cgagccaact ctggataata gagatgggtc acggtattgg acgctaggaa
    31441 ggagtgaatc ccaaaagtct tggctccttt ttccttcaag atagcaaagg cttcaaagag
    31501 ctggtccttg gtcatgccaa acttagcctc cccaggattg tccataatgt ctgtccccag
    31561 ttcaaaaacg cctccaggat tataacgaca agagatgatt tctggaatgc ctgctactct
    31621 ctccagatgt tcaatatctt caaaggcatc caagttaatg gtcgcaccca attcacgtgc
    31681 ataggcgtat tccttgtctg gcgtgttgtt ggaagagaac ataatctcag aacccagaaa
    31741 gtccagttta tggctcatca aaagctctac ataactagag cagtccacac cacaaccttc
    31801 ttcttggaga attttcaaaa tagctggagt tggagtagcc ttaactgcaa aatattcctt
    31861 aaagcccttg ttccacgaaa aagcttggtt gacggctctt gccttctcac gaatcccctt
    31921 ctcatcatac aagtgaaagg gagtcgggaa ctcggcaaca atcgcttcta actcttctct
    31981 attgataaat ggtgttttca taagcttcct tctattctgt ttgcaaagaa aggctgggac
    32041 aatcgttcca acctttagtt ctatctctta tttatcttcg tcaaagatat tgccaacctc
    32101 aacatcgatg gcttggttct tgacatcaat attggttacc ttcaagagtg acttgtagtc
    32161 aaactgcttt tcacgttctt cttgggcatt gtccgcaaag accgctacac ctgccagttc
    32221 tgagtcgaac tcgcgcaaga gactaatcat accattgacc gttccgccac ctttcaagaa
    32281 gtcatccaca atcaagacac ggctgcctgc cttaagacta cgttttgaaa ggaacatttt
    32341 ctcgatacgg tcaccacttg aacctgaaac atagttgacg ctaacagttg aaccttcggt
    32401 aattttcagg tcacggcgca caatgacaaa agagacattg aggacattgg caactgcatt
    32461 tgcaagtggc acacccttag ttgctacggt cataaccgcg tcaatttttt ggtccataaa
    32521 gcttttggca ataatacgac caatattttt caagatggct ggtgtgctaa gcaaatcaga
    32581 cagatagata taaccacctg gcaagatacg gtcactttct gacaacttgg tacgcaagtc
    32641 ttcaaccatt tccttagcat cctgactcga aatagacggt gtgaagatga cacctccgcc
    32701 agccccagtc actgtctgga tatgaccgat ttcaatttcc tcaaaggcgc gtttgataat
    32761 gacgatatct tctgagatgg atgatttagc agactcatac ttttcagcaa aagtattgag
    32821 actagttagt ttataaggat tattaatcaa atagttggaa atgacaacca tccgatcact
    32881 tcttcttaat ttcatttcta tttcctattc catttttatt caaaaaatca aaaagcaaac
    32941 tagaaagctg gtcgctggtg gttcaaaaca ctgttttgag attgtcaata gaactgacaa
    33001 accctgtaat atacctgcat atatacatac gacaaggcga tactatccta gtttgaagag
    33061 attttcgaag agtattcatt tttgtctttt acttattata ccatattcac ataaaaaaac
    33121 gaacattctt atcctaaaaa atgctcattt ttcttaaatt atcaatctaa atctggttta
    33181 tagaaggaac gattatccat agcgaagatt ttattggtca tctctccttt atccaccaaa
    33241 gccagagctg ttgacatcat catcatgctt gcatccagat tgtcaatcat atggataatc
    33301 tctgcctcca taatacgtgg acggactgga cttccatatt caagcaagcc gtggtgactg
    33361 aggatgacat gacgaagcaa aacgacttct tccttggtat catcgatgcc gagttccata
    33421 actgtcttgg taatttcgct atcaatgaga gcgatatgtc caagaagatt acctcgcact
    33481 gtgtactctg tctggtctgg ccccgtcaac tcgataacct tagctaagtc atgcagcata
    33541 atccccgcat agagcaggct cttattgagc tgaggataaa cttcgctaat agcgtctgcc
    33601 aaacgcacca tggtcgccgt atgataggcc aagcccgttt caaaggcatg gtggttggtc
    33661 ttggcagctg gataggagta gaattcctta tcatacttgg tgtagagatt tcggacaatc
    33721 cgttgccaga caggattttc aattttgaaa atcatttgcg acatgtagtc acgaatttcc
    33781 ttgacatcaa ctggtgactt gaccttgaaa tcagctgggt cattgggttc accagcttga
    33841 ggcaggcgga gagtaatttg attgacttga ggggtattgt tataaacttc tcggcgtcct
    33901 ttcatgtgga caaccttacc tgcggtaaag gcctcaatgt tatgaggttg ggcatcccag
    33961 agcttcccat caatctcgcc actatcatct tggaaggtaa aggctaggta gtttttccca
    34021 gctcgagttt gcctcaggtc agctgatttg attaggtaaa agccttcaaa taactcatct
    34081 tttttcatgt gactaatctt catattcttc ctcattttct tgaaaatgga gtagatcaag
    34141 cgcaggctca ccttctgaca actcaatgtg acggagcgtc cgctcgatag ctatggtacg
    34201 acggtttaat aattcatcaa tattgccaga ggcatgttgg agatgttttt gtgccttgac
    34261 cagaatacca ccaaacttgc caaactcggt cttgacactg gcaagagtct tgctgatatg
    34321 gtcggcactc ttttggatat taagggtctt gaaaccaact gatagggagt taagaagggc
    34381 tgatagggta cttggtcctg caacgataat ctgttcttcc cgtctcaaat catcaaagaa
    34441 gaccggattg cgcacaatct ctgaataaag accttctgtc ggaacaaaca agattccaaa
    34501 attggttgtc cgaggcggtg ctatgtactt gctcttgata tccttggcaa agcgcttgac
    34561 gcttgctagg agtgacttac gacagcgttc aatctcatcc ttgtcacctg tctcataggc
    34621 ttcttccaag cggtaataat ctgccagtgg aaacttagag tcaattggca gatagacgta
    34681 ttcttggtcg ccttgtccgg gtaacttgat ggcatactcc actcgttcac tagagttttc
    34741 aaccgttgcg tattctcgtt cgtactgggc aggtgtcatg atgtcttcaa taatttgccc
    34801 cagttgcaat tctcccagaa tacctcgcgt cttggttcca gagagaacct tgttaagagc
    34861 tccgacatca cgggcaactg tctgcatttc tccaaggcca cgattgacag actccagttg
    34921 tttagaaact gtttcaaagg aagcctgtaa gcgtgtctgc aaggtctttt ctagtttttc
    34981 ctcgaccgtc tggcgcattt gttccaaacg ttgctcattt gattcctgca aggcttggag
    35041 acgttggtct gtcttgtctc tagtttggag gagattatct gtcatttctt gacggacttg
    35101 ggtcaggcct tggtgcaatt caatccgcac ttcttgcaaa cggtcgctga cagccacttc
    35161 caaatctttt tggtctaact ggctggcttg tctggcttgg tcaaagcggt aatccaactg
    35221 gtctgacaaa tgatctgcct gatcctccaa gctcttactt aagtgtttct cctgcctatc
    35281 ctgcctttgc caaatcagaa agagaccagc taggttggca attaataata gaataagtaa
    35341 actttccatc ctacctcctg tccttgctat gcagtacgac cacataacca tctgggcaag
    35401 ttaccgacac ttccctatct atatattcgt tagaagcgta cactttttta aagaaaaaat
    35461 tctcctctgt caactcatac ttagctccaa gaatagtcag ctggctatcc cgaactggca
    35521 taaaggctag atagtcgtag tctgaacgag gttctagctg actggtccct tctgaacaat
    35581 aggcaatcaa attttgccca tcctcaattt ctatttgacg catatagggt gccaacttag
    35641 gattgctagg tagaaagaca ttggccaaca tatggtcaat acggccaccc aaggcaccga
    35701 aaatagtgac ctgagcctga ggattttgtt caaagatggt taagagagcc aattccagat
    35761 ctgtatcatc cttttctggt cgggcttgga caaaatactg ggcacgtttt tgaatcacct
    35821 gtcgctcttc ttccgtcaca gaatcaaaat ctccgactgc tagagcaaga ggtaagtctt
    35881 cttccaagac ccagagcgag cctcgatcca ccccaacaaa agcatcaaaa tctgtccgat
    35941 aatgaccgcg gtttccgcct gcaaaaactg caaccctagt ccagttgttt tctgagagtt
    36001 tgtactcgct cattgacttc tcccttaaag acataggaac ctgctacaaa aacagtcgca
    36061 ccagcttctt tggcttgagc aatagtttgg tcatcaatcc caccatccac ttcgatttca
    36121 aagttcaaac ctttttcctc acgaagagca accaactcac gaaccttatc catggtttct
    36181 ggcagaaagg cttgcccacc aaaacctgga ttaaccgtca tgactaaaac ttggtcaact
    36241 agatgaagga cgtgcttgat ggcttcaact ggtgtgccag gattgataac gactgaaggc
    36301 ttaactccga gtgaacgaat tttttggagg gcgccatgaa tatgaggtgt tgcttctaca
    36361 tggatactga tgatgtctgc acctgcacgc gcaaaatctt ccagatgatg ctcagggttt
    36421 gacaccatca agtggcaatc gaaaaccatc ttactatgag gacgaaggct ctcgaccaca
    36481 cctgcaccaa aactgatttg cggtacaaaa tgactgtcca tgatatcgat atgggcatat
    36541 tctgccccag ttgcttctag acgtttgatt tcacgttcaa agttggcata atctgctgcc
    36601 agaattgacg gagcaatctt gtattgagac ataggtttct ccttattttg gaattttttt
    36661 gctgactttt ttataggttt ctctacgatt ttcaatttca ctaaggaatt gcaggtaatt
    36721 gtcaaaacgg aaggttgcaa taacaccctc ttcaacagct ggtttgacgg cacaagacgg
    36781 ctcatgggta tgggtacaag tacggaactt acaatctcgg ctaacagtag caatctctgg
    36841 gaaagcctga ttgaggtctt cagcccttga tacttcatag tccaaggatg aaaatcctgg
    36901 tgtatctgcg attttacccc cgttgagatt gtaaaaacta acagctcgag tggtatggcg
    36961 accgcgacct agactgtctg aaatttctcc cgtttcaaga ttgaggtctg gtgcgatttt
    37021 attgagaaga gttgacttcc caacacctgt ctgccccata aagaccgtaa ccttgcctgt
    37081 taacaaagac aggagttcct ctttactggt cacaaagtca tagccgatgt caccataggt
    37141 ctgctggtaa aaatccagtt ctcccctatc ttccaacaaa tccattttgg aaatatagac
    37201 aatgggatgg atgcccttgt gctccaaaag aaccaagaaa cgatccagca aattgctgtt
    37261 aaaatcaggt tccttgacgg acatgattac tacagcttga tcgatattga caataggcgg
    37321 acgaaccaga ctgtttttcc gttcgtgaat tttgaggata tagccttctg aattttcctc
    37381 ggcagagaaa tctacccagt ccccaacata aggggtatgg ccttttttac ggaaattccc
    37441 acgcgcgcgt gtttgataaa cctggccatc actctccaca tagtagaaac ctgccaaggc
    37501 tttaatgatt tgtccctgca tcttagagtc cttgcccttt aagtgcgtct gctagaccgg
    37561 caaattctgc caagctgaga gcttccccac gcacacttgg tgacaagcct gcctggtcca
    37621 aagccttggt cagcttgtcc ttgacctctt cagtcttacc aaagtaacct gtcaagttat
    37681 tccacaaggt cttgcggcga tgggtaaaac tagccttgga aaccttaaag aaaaagttct
    37741 catcttctac tgctacggct ggctctggac gacgcaccat tttcaagatg gctgaatcca
    37801 catttggcgc tggcacaaag accgtacgag gcacgataaa ggcaaccttg gctgtcatgt
    37861 aatactgcac ggcgatagac aagctaccgt aagccttggt gttaggctgg gctgaaatgc
    37921 ggtccgctac ttctttctgc atcatgacca caaactcaca aaaaggaatg ccactctcaa
    37981 tcaagtgcat gagaataggc gtcgtgatgt agtaaggcaa attagccact accttgattg
    38041 gcaggttagg atttttaaaa ttttggatat gttgcgccaa atcaaccttg agaatatctt
    38101 cgttaactac agtcacatta tcaaaatcac gcagggtatc taccaaaatt ggcaccaaac
    38161 ggtggtcaat ctcaaaagcc atgacttggg ctgcacgctc agccagaaac tccgtcaagg
    38221 caccaatacc tggcccgatt tcgatgacat tgacctggtc atcaatttca gccgtatcca
    38281 caattttttg aaggatattg gtatccgtca ggaaattttg cccgaaggac tttttaaagg
    38341 taaaaccgtg acgctccagc actgccttgg tcactctata atctgcaatt ctcatctatt
    38401 ctcttttcta ttatctgtta ctactattgt aacacattcc ccttgtattt tgggaatgaa
    38461 aatcatacca aaaaactatc tttcctcatg aagaaagata gtcttggaaa tctttaaaag
    38521 tggccttaac agttctctcg aaacatgcgt tcaaaaaaat cagcttcttg ataacttcga
    38581 ttttcaggta gggtcaaatc cacatcctcc tccacatcat ccactgtcag ttcaaccgtc
    38641 tgaggtaaat ttttcaaacg ataatgcttt tgcctttgcc cttcaatact agcaaaatca
    38701 agcaaatagc catgcactcg gatttgaacc aaaaggagat gattggtcat attttccatg
    38761 atgaggatat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    38821 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    38881 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    38941 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    39001 caagggtgga tttttcaaaa tagtcttagc aagggcaact cgttgggcct ctcccccaga
    39061 taaagtataa attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    39121 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    39181 attttctttg attgattggt tttctaagag gccaaaattt tgaaagagat agcccatctg
    39241 atctcgaaaa tactcacgag tgggaatggt ttttaaatct ttcccctgat agagaaccct
    39301 tcctccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    39361 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    39421 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    39481 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    39541 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    39601 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    39661 gctcatagat tgtcatacca gcaagacgtt taatcataag ctcccgtctg aactgctcaa
    39721 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    39781 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    39841 ggctttttac caagtaagaa accttgtgat acagaccttg ctcttttaga gctgtgatgc
    39901 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    39961 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    40021 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    40081 aagctagcct tacctgtggg aagtagtgtt tctgactcgt cacttctaca ctttcagatg
    40141 aaaagttttg caggtaatct gtaaacaatc cttggtagta ggcagactgc tctcgcaagc
    40201 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tcaataaact
    40261 ctgaagaaac ggtaatcttt tcttctatca gatagcgcgg cgagacatag ataacattcc
    40321 ctgacggtat gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    40381 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    40441 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    40501 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    40561 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    40621 cagctaagag ttgccccacc atcatcaatg tcatcatccg tttgagaggg agtttccctt
    40681 tcaatagatc caccagacta ttttcctgta aaccaagtag atggacgaca cttagtaagg
    40741 tagaaatccc tgccagggtc aatccataaa gtagaagagc aatgatgacc agttgtaccg
    40801 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    40861 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    40921 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    40981 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    41041 ccgccaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgatagc
    41101 caagttcttt caaggtggtc tgtaagctca ctccatccaa acttcctgac acaatcaagt
    41161 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    41221 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    41281 caacgattcg acgggcgatg agactattat gctctaccgc caagtgactc aaagcctctg
    41341 tcacctcttc gcgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    41401 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    41461 ataccaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    41521 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    41581 acattatagt agaatgcaac tttctctccc caagaagtac gaatccatgc acgagaagtc
    41641 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    41701 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    41761 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgctac acttccacct
    41821 aatgttgctg caatgctcgc tacaagagct aattttttaa ctgtttgttt catattgata
    41881 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    41941 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    42001 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    42061 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    42121 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    42181 gattcactat gtttataaat atttttttaa atcttcttgc cattgttttt ctaacatagt
    42241 aactaaataa gaattttcta ttatatcagc aaatagcttc gatttctgat agaactgttc
    42301 ggcagaaaca taatcattgt ttattattag agataatttc cactccaaca ttaatataat
    42361 tggtttcttc tggaaatctt gtgttttttc cattatatga ttaaggctaa agatataagc
    42421 tcctagtgaa tcataagacg acaagttatc caaacaggct agacccgaaa acaaagtgtt
    42481 acttaaagca aacagatatt ctgatgcaat taattctaca tgatttgtca aacgaactaa
    42541 aaacgaatga attctgttaa tttcttcaat ctgattttga ccttgtttta tctttgtaag
    42601 cactatagca aaatataagt tgataacttc taattcattt atcaaaaaca attccttatc
    42661 ataaattgtt ttaaaataat cgtccagtac ggtttccccg tattctggtc gtccacttcg
    42721 aataacatct atcgttgctc tagtagcttc aaaccatact ttttcctcat taggaagttg
    42781 ctcataaaat aaatcctcta tctcttccaa acacgcttcc ttcttatcgt actcctcttc
    42841 tttaccatag attggttcac gtaaaatctg gtatttcaat tctaaataag cagaaggaag
    42901 agctgaaaaa tccggcataa ggctataaac tggaactcct agccggcgag caatataggc
    42961 taacttgggc aaactcggtt gcgaagctcc actttcaatt cgcgacagtt gacgaactgt
    43021 cagttcttgc tcatctccac aaaaatctgg acgactaatt cctttttcta tccgaatctc
    43081 tttaattttt tgaccaatta acatcagacg cctcctattc tacctgcttc gaaaaatact
    43141 gtgaaactta aaaaattgta acggctacat ctttcctact cataagattt catagcttct
    43201 tccacttctg ccaaagtaac cccaaacaac tctaggcgtt tgaggagttg cttgccgttg
    43261 gaatagccga ttcggagagt ctctccgagg tattctctac gcttacggct gtctgcccct
    43321 gctagaaaac caaggcgaat caaatcgcta cgactaatgt caaactggct ctcatgttca
    43381 aattgttctg tcacctgagc tagagccgtt ttcaggtctt catagctggc atgctcaatt
    43441 cccagagaac gccccttggt cttggacttg ggaacagctt catctcgctt gagaaaggca
    43501 tgctgaactg ttggaatgac cgtcatgatc atgcgccgaa tccgttctcc attaaaatct
    43561 gggtctgtaa agacaatgac tccatgacgt tggtgcaggc gctgaatccg ctctatatcc
    43621 tgatcattga tggcagaacc tcgagtctca taggtctcca catcgaaata acgcttgaga
    43681 ttgaccgtat catcacgccc ttcaaccacg ataacttgag aaattttctc tttcattact
    43741 tgctgtccag tccaaaaatt cgttctgcat ttgcagtcgt tgctaccgcc agctcttctg
    43801 tcgtcatacc acgcaagtca gcgataaagt cgaccacata gcgagtatag gctgttttat
    43861 tttcacgacc acgcttgggt acaggtgcta agtaaggcgc atctgtttcc accaaaatct
    43921 tgtccaaaag taactcttta gctgcttctt ggaggtcagt tgccttctta aaagtcacca
    43981 ctcctgagaa ggaaatggtc ataccaagat ccacaaactt ctctgcccac tcaagcgtcc
    44041 ctgaaaatga atgcatgata ccaccacgag gaccaacgcc ctcactcttg ataatctcat
    44101 aggtatcttc cagcgcatca cgggtatgga caacaaaagg caaatccaag tccttagata
    44161 gctgaatctg acggcgaaaa acctgctcct gcacctcttt gggcgctgtc atccaatggt
    44221 aatctaagcc aatttcacct aaagccacaa ccttgggatg ttttaactta tccaacaagt
    44281 aagcctcaac ttcctctgta taagtaccag cttctgtagg atgccaacca atagtcgcat
    44341 agagctgatc atactcatct accaactcca aggcacgctc aatcgtcggt ttatcaaaac
    44401 caacaatatt catctgtgtc acacccatct cagcagccaa ggcaatttct tctgcctcac
    44461 gacctgcaaa ttcttctaca ttcaagtgtg tatgtgtatc aaaaatcatc tcttctaacc
    44521 tcgttttcta tcttctatta taccaaaaaa gaggaggggc acctaatttt tcggtttccc
    44581 ctcctctctt caatagagag ctattctgct atcttttcta tccgatattg cccatctcct
    44641 attccacagt tagagacaga agagattggc tacattgata gaatattcct attcagctaa
    44701 agtatgtgat tatcttgggt tctcactttt ctcacccatc actaggattg atgacttctc
    44761 aaaatccccc ttataatcta actttaagta gagaatagaa ttttctagct gttctatttt
    44821 ctacgtctag tctttcttcc tagcaaagca aaaccacttg ttgccaccac tagaccaaga
    44881 ctagcaagtg ctgcacttga tgctgaacct gtgttaggta attgtttgcc agcaggtgac
    44941 tggtaggtaa catcttgcat tgttcctgca gttgcttgcg gtgcacttgt tgtcttagga
    45001 gcagcattag gagccactgg tctcttagga actgtaacca tggcaatggc ttgcactcca
    45061 atcgtttctg cttccttcac atcttccata gttttcgcat tttcaatctc tttgagagct
    45121 gcttgttttt ctgcttccac tcttgctaaa agttctgctt tttctttatc agaaagcggt
    45181 gcgcctttga tttcatcctg cttgtccttg gctgcttttt caatggcatt tttagctgat
    45241 tctttttcag tagctaattg cttagaagct tgtgattgag ctgagttttg tgaacctgtg
    45301 tgagctgatc cacccgcctg gctaccaccg ccttcattcg cattagcatc tgagcttcca
    45361 gtattgcctc ccttatctcc acctggtgta ttttctagct tatactctgg tgtagcttct
    45421 tgagttacag attcaccttt cgcagattgt tgaactgtat cttttcctag aatcgtcact
    45481 actgaaccat ctgggaatgt gattgttgct gtaccatctc cagctacttc aactttatag
    45541 taaaataaaa taataacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    45601 tttagaaaca gaggtgtact attctagttt caatctacta taacatcgct tccgaatcca
    45661 tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt agactcgagt tcctactgat
    45721 ttttgataga attcgtttgg attatgcagc caaaactttg cgtcctttac gacgacgagc
    45781 tgccaatacg cgacgaccat ttttagttga catacggtta cggaatccgt gtttgcgcgc
    45841 acgacgaagt ttacttggtt gataagtacg tttcacgatg aatacctcct catagatttt
    45901 gtattcgttt agccggctat aaagtgatca gttactaaac atactttact attctatctg
    45961 attctttcac ttttgtcaat agccctaggc aaatgtttcc agctttttcg aatgcaagcc
    46021 ctatctacga tactgtttca agaaacgagt catcttttct tggatttggg ctaactcatc
    46081 aacacgagga aggtaaacga tacggaagtg gtctggttcc tgccagttaa agcctcgacc
    46141 atgaaccaag agaacctttt cctgcttcaa gaaatcaagg acaaactgct catcatcatc
    46201 gatacggtac atattgcggt cgatttttgg gaagatatag agccccgcct tgggtttaac
    46261 ggcagacaaa cctggaatat cttgaatggc attatagatg aaatttcttt gctcgtagat
    46321 tcgtccacca ggaagaagca attcatcgac tgattggtga ccccccaagg aagtttgtac
    46381 gacttgttgg gccaaaacgt tagagcaaag gcgcatattg gacagcatat tgagcccttc
    46441 gatatagccc ttaacatgag tcttagggcc agacaagacc atccaaccca cacggaaacc
    46501 tgctatgcgg tgggattttg acagaccatt catgctgaca cagaagacat ctggtgccaa
    46561 gctcgccaca ggcgtatgca catgtccgtc cattaccatg cggtcataga tttcatccgc
    46621 aaagataatc aaatcgtttt gacgggcaat ctcaataatc tccagcaaga gtttcttagg
    46681 ataaagggct ccagttgggt tatttggatt gataaggacg attgccttgg tattggaagt
    46741 gatttttgac ttgatatcgt caatatctgg gtaccattca acagcttcat cacagatata
    46801 gtgaacggca tttcctccag ctaggctgac agccgccgtc catagaggat agtctggcat
    46861 tggcactaag acctcatccc cattgtccaa aagcccctgc atggacatga caatcaactc
    46921 actgacacca tttccaaggt aaatatcatc aatatctacg tttgggaatt tcttcagctg
    46981 gcaatactgc atgatggcct tacgggctga gaaaattcct ttggagtcag aatagccttc
    47041 actatcacgc gcattcataa tcaagtcatg aatgacctcg tctggcgctg taaagccaaa
    47101 ttctgctgga tttcctgtat tcagacgtaa aatcttttct ccattcgctc gcatccgcat
    47161 ggcttcttcc aatacaggac cacggatatc ataagcaaca tgctctaact tactagactt
    47221 gttatattct ttcatcttgt ttcctcaatt catcaggata gtaacattat accactagaa
    47281 agagaatgcg acaagtttac tgaaatgtgt tactagtttc gtatagaaga aaaaccttgc
    47341 taaaggcgag gttaagaacg tagagatagc aggtattttg caaagacaca tcacatacca
    47401 aaagataaac ctagaaaaag caagcctaga aaggagtcat aaagaagatt aaacatgagg
    47461 aaaagccccc atatcatcaa gtaatcccaa cgcccacttc gttttgcaac tagaaataag
    47521 attagatggt agagtacatg aaaaactaaa aatccaataa aacttggata aagaagcggt
    47581 accagactct ctaattgaca gatcatgatc acttctacca agactgaaac taggataatt
    47641 ccataataaa ggaaatttga tttttgaaaa gagtttttca tcattctccc ttccttcact
    47701 tctttcctgc tatcctttct tttattttat catatattta tatagagttt aagccctaat
    47761 attcttttga aaaatacttt ttttgcttta cttctatagt gaaaaggttt acaattatag
    47821 taagaaaatt tcaggaggtt tcattatggc acaacgttac caaaatatca tggtcgcaat
    47881 cgatggttct aaggaagcgg acttggcttt tgtcaaggga gttcattctg ctctacgaaa
    47941 cgacgctaaa ctcaccatcg cacatgtcat tgacacacgc gctctccaaa gcgtatccac
    48001 ctttgatgct gaagtttacg aagaactcca agtcgacgct gaaagtctga tgaaagagta
    48061 cgaaaaacgt gctaaagatg ctggggtagc agatgttcat atcgtcattg aaatgggaaa
    48121 tccaaagacc ctgctagcac gtactattcc agatgccgag gaagtggacc tcatcctcgt
    48181 tggcgcaact ggtctcaacg cctttgaacg cctcttggtc ggctcttcat ctgaatacat
    48241 actccgccat gctaaggtcg atttgctggt tgtgagagaa caagaaaaaa ccttataatc
    48301 acaaagaaaa ggagccccta gctccttttt gtttacgatt tatttctctc tttatggcgt
    48361 tcgtaagcct tgagctggcg ctgcagttcc tttttaatag caggttctgg agcatatttt
    48421 tcttcccaat tatctggttt taagatttta tgggtcactg gatcaaaatg agccttgcca
    48481 tctggaaaaa ttttccccat attggcctga tggacaatat caaaaatacg ttctgggtcc
    48541 acccccatca agacaaaact gccgtaggtg aagtaaagcg tgtcaatcaa ggcatccact
    48601 tgccctatca aatcttgctg agcaggtgtc ttcttggcta ctttatctgc tgccttatca
    48661 agggcctgat gaagttgcga tacagcttga ccaaaatctt cttcagaagg actggctgct
    48721 cgaacaaact ccaccaattc ttctatttta aaaccagccc tatgggttgc accctctaaa
    48781 tcccaagctc gaggttcttc ttgggttcgt tcatccatca tgtggtggaa ggtcttgacc
    48841 ttattgaaat gatagtcacg gctgacaaag actttttctg aagacaaaac accaaaatgt
    48901 tccaaggcct tgtggatccc atcttgttga ttgctagtgg taatgtgctt ggcagcttcc
    48961 ttgacactgc tactaccatt tcccatagcg accgacatac cgacgccagc cagcatttca
    49021 aggtcattat ctgagtcacc aaaagccatg acttgattga ggtcaaagcc atattctttc
    49081 ccaactcggc gaatgccttc taatttagaa tttccctgat tgatgacatc cgatgcaaaa
    49141 ggattgctac gtgtcaattt caagtcttca aaatcagctg ccgccttctc agattcttct
    49201 ggtgtcatca gcatcaaaac ttggtagata ggctgattca tcaggtgaag caggtcctct
    49261 tccttttggg gaacaacctt gctgaccatg cgattaaaag actgactcac cgtccgagtt
    49321 aaaacagagg gaacgaagcg actaattcgt tgggaaaaag aacccagacc aaaggacatg
    49381 attttagaac ccaacatggc atccttggtc cctagggcaa tctccgtgcc ctctttttta
    49441 gcatagctaa ttagatggcg caaatgtaac ttggaaatag ggctcgtgaa caagactctg
    49501 tctttactaa agatatactg gccattatag gttaccgcaa aatccagatc caaatcgtcc
    49561 atcaattcct taacaaaaaa aggtcctcgc cctgtcgcta cgccaactag taccccttgt
    49621 tctttgacaa tcttaatcgc atccttagtg gatttcaaaa cactcttgcg attgttgacc
    49681 aaggttccat cgatatcaaa aaaaacagct ttgacttcca tcctatccca atctcccctt
    49741 ttgtgataca atgattatac cacatttcag aaagagttag taaatcatgc ctaagaaaat
    49801 ccttgtttta catacgggtg gaactatttc catgcaggcc gatgcttctg gcgctgttgt
    49861 gacgagttca gataatccca tgaaccatgt gtccaaccca cttgaaggaa tccaagtcca
    49921 cgccttggac ttttttaacc ttccaagtcc ccatatcaaa cccaaacata tgctggtcct
    49981 ctaccagaaa attaaagagg aagcagataa ctacgatgga gtggtgatca cacacggaac
    50041 cgatacttta gaggaaacag cctatttcct tgataccatg gaagttcccc atatgcctat
    50101 cgttctaaca ggagccatgc gtagctccaa tgagctcggt agtgatggtg tttataatta
    50161 cctaagtgct ttacgagtgg ccagtgatga cagggctgct gacaaaggag ttttggtcgt
    50221 tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa acacatacga ctaatgtcaa
    50281 caccttccag actccaacac atggccccct cggtctcatc atgaaacagg aaatcctcta
    50341 cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat cacatacaag gtttagtccc
    50401 tatcatctcg gcttatgctg gtatgacaga tgagctgatt gatatgctgg atttagaaca
    50461 cttggacggt ttgattatcc aagccttcgg agctggtaat attcccaaag aaacggctca
    50521 aaaattagaa agccttctgc aaaaaggaat cccagtcgct ctggtatcac gatgctttaa
    50581 cggtattgcc gagcctgttt atgcctacca gggtgggggc gtacagttgc aaaaagcagg
    50641 cgttttcttt gttaaagaac tcaacgccca aaaagcccgc ttgaaactcc tcatcgccct
    50701 caatgccgga ctaacaggac aggctttgaa agactatatg gaaggctaat actcttcgaa
    50761 aatctctgca aaccacgtca cgtcgcctta ccgtatgtat ggttactgac ttcgtcagtt
    50821 c
//
LOCUS       DBEJZJ010000013        49208 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000013 DBEJZJ010000000
VERSION     DBEJZJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.13"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(66..782)
                     /gene="ldcB"
                     /locus_tag="ACL3R8_000946"
     CDS             complement(66..782)
                     /gene="ldcB"
                     /locus_tag="ACL3R8_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR1313848.1"
                     /translation="MKKRYIVLSGLLAVTLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(808..1269)
                     /locus_tag="ACL3R8_000947"
     CDS             complement(808..1269)
                     /locus_tag="ACL3R8_000947"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR1313849.1"
                     /translation="MCLICQRIEWIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMETSVKLRFLEEMSLVQEAVAKTFKAEKMNIELLGNGDAHAHWHLFPRR
                     SGDMRGHGLNGRGPVWWVPWEEMAAEDCQVKSHELEQMIKALSDELEKYTV"
     gene            complement(1271..2308)
                     /locus_tag="ACL3R8_000948"
     CDS             complement(1271..2308)
                     /locus_tag="ACL3R8_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR1313850.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPSQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(2406..3731)
                     /gene="brnQ"
                     /locus_tag="ACL3R8_000949"
     CDS             complement(2406..3731)
                     /gene="brnQ"
                     /locus_tag="ACL3R8_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR1313851.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3902..4189)
                     /locus_tag="ACL3R8_000950"
                     /pseudo
     CDS             complement(3902..4189)
                     /locus_tag="ACL3R8_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(4349..4927)
                     /locus_tag="ACL3R8_000951"
     CDS             complement(4349..4927)
                     /locus_tag="ACL3R8_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR1313852.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFLLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4981..6381)
                     /gene="pepV"
                     /locus_tag="ACL3R8_000952"
     CDS             complement(4981..6381)
                     /gene="pepV"
                     /locus_tag="ACL3R8_000952"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR1313853.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(6394..6999)
                     /locus_tag="ACL3R8_000953"
     CDS             complement(6394..6999)
                     /locus_tag="ACL3R8_000953"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR1313854.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIADRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            7170..7970
                     /locus_tag="ACL3R8_000954"
     CDS             7170..7970
                     /locus_tag="ACL3R8_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313855.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(8152..8949)
                     /locus_tag="ACL3R8_000955"
     CDS             complement(8152..8949)
                     /locus_tag="ACL3R8_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1313856.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNVIEVEDGELVNILFRKVAYDYEAELEFAK
                     SKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8939..10786)
                     /gene="uvrC"
                     /locus_tag="ACL3R8_000956"
     CDS             complement(8939..10786)
                     /gene="uvrC"
                     /locus_tag="ACL3R8_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR1313857.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     GVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNEP"
     gene            complement(10825..11526)
                     /locus_tag="ACL3R8_000957"
     CDS             complement(10825..11526)
                     /locus_tag="ACL3R8_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR1313858.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(11605..12837)
                     /gene="murN"
                     /locus_tag="ACL3R8_000958"
     CDS             complement(11605..12837)
                     /gene="murN"
                     /locus_tag="ACL3R8_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR1313859.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12842..14062)
                     /gene="murM"
                     /locus_tag="ACL3R8_000959"
     CDS             complement(12842..14062)
                     /gene="murM"
                     /locus_tag="ACL3R8_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR1313860.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQTIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(14174..14953)
                     /locus_tag="ACL3R8_000960"
     CDS             complement(14174..14953)
                     /locus_tag="ACL3R8_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1313861.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(15022..16683)
                     /locus_tag="ACL3R8_000961"
     CDS             complement(15022..16683)
                     /locus_tag="ACL3R8_000961"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR1313862.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16858..19080)
                     /gene="recJ"
                     /locus_tag="ACL3R8_000962"
     CDS             complement(16858..19080)
                     /gene="recJ"
                     /locus_tag="ACL3R8_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR1313863.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGMVQEIYDFLMEKE
                     "
     gene            19357..20115
                     /locus_tag="ACL3R8_000963"
     CDS             19357..20115
                     /locus_tag="ACL3R8_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1313864.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            20126..20920
                     /locus_tag="ACL3R8_000964"
     CDS             20126..20920
                     /locus_tag="ACL3R8_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR1313865.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20933..21610
                     /locus_tag="ACL3R8_000965"
     CDS             20933..21610
                     /locus_tag="ACL3R8_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1313866.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            21620..22279
                     /locus_tag="ACL3R8_000966"
     CDS             21620..22279
                     /locus_tag="ACL3R8_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1313867.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            22537..23727
                     /locus_tag="ACL3R8_000967"
     CDS             22537..23727
                     /locus_tag="ACL3R8_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR1313868.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(24048..24929)
                     /locus_tag="ACL3R8_000968"
     CDS             complement(24048..24929)
                     /locus_tag="ACL3R8_000968"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR1313869.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(25070..26398)
                     /gene="vncS"
                     /locus_tag="ACL3R8_000969"
     CDS             complement(25070..26398)
                     /gene="vncS"
                     /locus_tag="ACL3R8_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR1313870.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(26395..27051)
                     /gene="vncR"
                     /locus_tag="ACL3R8_000970"
     CDS             complement(26395..27051)
                     /gene="vncR"
                     /locus_tag="ACL3R8_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR1313871.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(27100..27183)
                     /gene="pep27"
                     /locus_tag="ACL3R8_000971"
     CDS             complement(27100..27183)
                     /gene="pep27"
                     /locus_tag="ACL3R8_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR1313872.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(27363..28742)
                     /gene="vex3"
                     /locus_tag="ACL3R8_000972"
     CDS             complement(27363..28742)
                     /gene="vex3"
                     /locus_tag="ACL3R8_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR1313873.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28794..29441)
                     /gene="vex2"
                     /locus_tag="ACL3R8_000973"
     CDS             complement(28794..29441)
                     /gene="vex2"
                     /locus_tag="ACL3R8_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR1313874.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(29454..30731)
                     /locus_tag="ACL3R8_000974"
     CDS             complement(29454..30731)
                     /locus_tag="ACL3R8_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313875.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(31088..31258)
                     /locus_tag="ACL3R8_000975"
                     /pseudo
     CDS             complement(31088..31258)
                     /locus_tag="ACL3R8_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(31401..32000)
                     /locus_tag="ACL3R8_000976"
     CDS             complement(31401..32000)
                     /locus_tag="ACL3R8_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313876.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYAPLNDVTKYAR"
     gene            complement(32242..33126)
                     /locus_tag="ACL3R8_000977"
     CDS             complement(32242..33126)
                     /locus_tag="ACL3R8_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1313877.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(33130..33516)
                     /locus_tag="ACL3R8_000978"
     CDS             complement(33130..33516)
                     /locus_tag="ACL3R8_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR1313878.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(33509..34852)
                     /gene="cysS"
                     /locus_tag="ACL3R8_000979"
     CDS             complement(33509..34852)
                     /gene="cysS"
                     /locus_tag="ACL3R8_000979"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR1313879.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(34934..35818)
                     /locus_tag="ACL3R8_000980"
     CDS             complement(34934..35818)
                     /locus_tag="ACL3R8_000980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313880.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(35830..36447)
                     /gene="cysE"
                     /locus_tag="ACL3R8_000981"
     CDS             complement(35830..36447)
                     /gene="cysE"
                     /locus_tag="ACL3R8_000981"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR1313881.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(36463..38676)
                     /gene="pnp"
                     /locus_tag="ACL3R8_000982"
     CDS             complement(36463..38676)
                     /gene="pnp"
                     /locus_tag="ACL3R8_000982"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR1313882.1"
                     /translation="MAKQVFQTTFVGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(39361..40227)
                     /gene="metF"
                     /locus_tag="ACL3R8_000983"
     CDS             complement(39361..40227)
                     /gene="metF"
                     /locus_tag="ACL3R8_000983"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR1313883.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(40291..42540)
                     /gene="metE"
                     /locus_tag="ACL3R8_000984"
     CDS             complement(40291..42540)
                     /gene="metE"
                     /locus_tag="ACL3R8_000984"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR1313884.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(42801..43067)
                     /locus_tag="ACL3R8_000985"
     CDS             complement(42801..43067)
                     /locus_tag="ACL3R8_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1313885.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(43193..43640)
                     /locus_tag="ACL3R8_000986"
                     /pseudo
     CDS             complement(43193..43640)
                     /locus_tag="ACL3R8_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            43796..44797
                     /locus_tag="ACL3R8_000987"
     CDS             43796..44797
                     /locus_tag="ACL3R8_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR1313886.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(44865..47270)
                     /gene="pheT"
                     /locus_tag="ACL3R8_000988"
     CDS             complement(44865..47270)
                     /gene="pheT"
                     /locus_tag="ACL3R8_000988"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR1313887.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDK
                     APYYAARILENVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAASSLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(47347..47856)
                     /locus_tag="ACL3R8_000989"
     CDS             complement(47347..47856)
                     /locus_tag="ACL3R8_000989"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313888.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(47856..48902)
                     /gene="pheS"
                     /locus_tag="ACL3R8_000990"
     CDS             complement(47856..48902)
                     /gene="pheS"
                     /locus_tag="ACL3R8_000990"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR1313889.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        13870 a        11236 c         9279 g        14823 t
ORIGIN      
        1 atagaaccga cgcagtcagt aggtaagacg acgctgacgt ggtttgaaga gattttcgaa
       61 gagtattaat cgacgtagtc tccgccttca aagccatagt attcttccaa actgagacca
      121 cttgcagcaa tttctttagc ttcttttcct acataacgca ggtgccattc ctcagccata
      181 tagcctgttt ccttttcctt gcctttgaga taacggacaa caaagccata atcagctgca
      241 tgatccaaga gccattgggc tgctttttct tctgtcacca aatcaccatc agtcccaatc
      301 acatcaaagg ccaagcctgt ctggtgttcg ctatagccag gacgggcaga gtaacggtca
      361 gctgctgcct ttccatcttg gttgacataa tcttgataga gcttggtctg agtttcataa
      421 cttctaaaac cactgtaatg atcactaata gggaaacctg cctcttgcat cgctttgatg
      481 agtttgacca actcagcctt ggctgttgga ttttccccgg gattatagtc tttcgacaaa
      541 ggataatgtt tattggctac gatgatttcg tcgtattttc cttggatgct gtagtaatca
      601 cctttattga ccacttctgc ttttttctgg gcagcccctt gagacttact gccgactgtc
      661 ccatcagctt tggctgtctg ttctgtctta gctgtgccat cttcattttt tgctttttct
      721 tgtgaacaag ctgctagggt tactgccagc aaaccagata aaacgatgta tctttttttc
      781 attttttctt cctctattct tcctctctta gaccgtgtac ttctctaatt catcggataa
      841 ggctttaatc atttgttcca actcatggga tttcacttgg caatcttctg ccgccatttc
      901 ttcccagggc acccaccaga ctggaccacg gccattcaat ccatgacccc tcatatcacc
      961 tgaccgtctt ggaaagagat gccagtgagc gtgggcatct ccatttccta gaagttcaat
     1021 gttcatcttt tcagctttaa acgttttggc aacagcttct tggaccaaac tcatttcctc
     1081 tagaaaacga agttttacag aagtctccat atgatggagt tctgtgacat gctcttttgc
     1141 tagaaataag gtatagccct taaagtattg gtggtctcca ataacaacat agcctgtttc
     1201 tagttctttt acaaagtagg gattttcccc tgccttgatc cattcaattc tttgacaaat
     1261 caagcacata ttagtctacc aatgcactct taagataagc atcgaccata cgctcagtcg
     1321 ccactactga atcaatgtgt gttcgttcgt aagagtgact tgactcaata ccagctccaa
     1381 ggagagcatg ctttacttct gctcctgcag acatagctgc cgaagcatcc gaaccgtaaa
     1441 atggataaat gtcgagctta aatggaatat cttgctcctt cgccaaaact accaagtgtt
     1501 gacggaagtc atagtgatag ggacctgaag cgtccttgac acagatagac actgtatact
     1561 catccgtctg ctggtcatct cccatagctc ccatatctac agccagatat tctactacct
     1621 gacttggaat attggagttt gcaccgtggc ccacctcttc gaagactgaa aaagcaaaat
     1681 gagttgttac tggcaattca atcccctctt ccttataaac acgaagaaga ttgagcaaaa
     1741 ttgctgcgct gaccttgtca tccaagtggc gagacttgat aaaaccagtc tctgtcacga
     1801 cagttcgtgg atcgaagctg ataaaatcac cgacctcaat cccaagagca cgagtttctt
     1861 tttcattgct tacttttaca tccaaacgca cttccatatt gtcctgcgtg cgttctgcag
     1921 ttcctgcatc cttgtagaca tggcaagaag tttggtggat gaggatggtt cctgatacct
     1981 tttgacctgt gctagccaca tgaacggtac agttttcacc ttcaatcatg ttccaaggaa
     2041 aaccaccgat acggtccaat ttaagacgac catctggttt gacagcacga acaatagcac
     2101 ccagcgtgtc cacatgggca gtcacatagc gatgttgctc atcattttga cctttgatgg
     2161 tcacattgac accacccttg gctgtgcgaa ctggctggta accaaaacct tctagagtct
     2221 tgactaaata attcgaaatt tcacgagtga agcccgttgg cgatgcgatg gctgtcagtt
     2281 ctttgatata ttctactgtt tgattcattt cttcacctct ttcgctacct attataacac
     2341 atttatcatc ggataaaaaa agaaaatcac tcctgtagac ttggctacaa aagtgattta
     2401 agtgattatt ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac caatgagagc
     2461 aagattccaa caatggctgg caccaaccat gggagagatg ccttggcaaa aggaagaacg
     2521 ctaacaagat ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct tgcaatggca
     2581 ataactgtaa ccacagcaat tgtcaactgc atacctggtt ttgaaagggc aacaaatttg
     2641 ttgacaatga caatcataac gatagcaatc gtgattgggt acaagataac cagtactgga
     2701 attgagtact tgataatcgc atcaagaccc aaattggcaa tagcaaatcc aatcaaggta
     2761 aaggctgtcg cataaacctt gtagctgatt tgtgggaagc gctcattaaa gaactcagct
     2821 gttgacacaa tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat agctgcaagg
     2881 aagagttgag ctgttgagcc aaagatttct tgagtggctt gtgacaagat gtaaacacct
     2941 ggtgttccac ccttcatcgc ttcagctggt actgggaaat gatttccaag aaaacctaaa
     3001 ccgatgtaaa gagcgctgaa ggcaagggca acaacgatac caacaaccca aatagttgaa
     3061 atgtattctt tcttacttga aaatccaagt tgtttcaagg tttgaactgc gattacgcta
     3121 aaggccactg aggcaagggc gtccaaggta ttgtaacctt ctaggaaacc tgtaccaaag
     3181 gcagaagctt gataagcagc tgaagcagct tgaggacttg ttccaccata tttgatagct
     3241 cccagaacga ccaagataac aatcaaaatt gcaaagactg gcgttaaaat acgtccaatg
     3301 cggtctaaga tttttgatgg attaagcgaa atcaaatagg ctgccgcaaa atacagaacc
     3361 gtaaatacaa tcaagccaag tcctttattt gcatccgaca aaagggggct aatccctact
     3421 tcgtaagctg ttgtagcagt acgtggggta gcaaagaatg gaccgattga caagtaaaga
     3481 actgagaggt aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc gtagatatat
     3541 cctttaggat ttagcgttcc aataataagg gtcaagacgg cgataccaac gcctgaaaag
     3601 acaaaacctg cgatggcagg aagaaaatgt tctccagata gagcacctag agaaggcgga
     3661 aaaatcaagt tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt tagggtacct
     3721 tttttagcca taaaaatctc cttcatattt ataaaatact gacctagtat accacgatta
     3781 ggagtctgaa aaaagcatca cgaggcaaat attaaatgtt ttcaattttc ttaaaaataa
     3841 gaattatcta aaaataaaac tctcctaccc agtccacacc aagtaggaga aatgcaaaat
     3901 tttaaagttc ttcaaaggct aacatgccac cctggacatt gataacgtta taaccttgtt
     3961 ctaacaggaa ttggcaagca cgcgccgatc tcattccaga tttgcaaata atataatgca
     4021 agcgatcttt gtccaattaa tcataactat cagccaattg actaagcggt aggttgtggg
     4081 taccttctaa atgaagagct gcaaactcat ccacttctct cacatccact agagaaagct
     4141 ggtcgttttg gtaaagctga taaaatgcgt caaaggctat ttctttcatt ctttttcttc
     4201 taatactctc cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgtg cgtatgttac
     4261 cgacttcgtc agttttatct gcaacctcaa agctgtactt tgagcagcct acgactagct
     4321 tcctagtttg ctctttgatt ttcattgact ataaaatggt tttaattctt tttttcaaat
     4381 ctggcactac ttctgcctca aaccaaggat ttttggccat ccagatttga tttcgtggtg
     4441 atgggtgaac tagcagaaaa taggctggca gatagtcttt atagtgtttc accctctccg
     4501 ttaccttccc actgattttc tcctgtaaat agtaggcttg ggcatattgc ccaatcaaga
     4561 gggttaactg aatatcaggc aattcctgta agagctgcgg atgccatttt tctgcaaaac
     4621 ctgtacgagg cggaagatca cccgacttgc catgtcctgg aaagtagaaa tccataggca
     4681 aaacagcaaa ataacctgaa ttgtaaaagg tatcttcatc tacacctagc cagtcccgca
     4741 agcggtcacc acttttatct ttccagtaaa ggcctgcttc ttgagtttta agtcccggag
     4801 cctgaccgat gatattgatg cgagcagttt ttggcgctgc aaagagaggc tcaatgccac
     4861 gctctgtata gctggcattc tgcgaatccg ccatgatagc ctgtttgatt ctttcgattt
     4921 gagacatcta ctttccctcc aaaaagaagt ccaagcataa gatctcagac ttctatcgtt
     4981 ttatttgatc aattcgtaaa tagcttcggc ataaattgct gctgctcgga agagatcgtc
     5041 caaggcaata aattcattgg cttggtgcat agtatcaatt gagtctggga acatagcacc
     5101 ataggcaact ccgcgctcta acaagcgacc aaaggttcca ccaccgatga cttgctcatg
     5161 accttgtagg ccagtttgtt tttcatagac attcaacaag gtttgcacaa gtggatcttc
     5221 cattggcaca tagtgagggg tatgaccatg ttctgataga ctgacagaag caactggcaa
     5281 gttttctagg attgacttga tttgttctgg acttgttcct tttggatagc ggatgttaag
     5341 ggcaatggta ttatcagcac ttgtttcatc gaagcggaag acgccggcat tcatagaaag
     5401 agcccccatc ttttcatcca catgagcaat cttgagattt tcaccctcat gatcgttcaa
     5461 gagaatttta cctgcgatgt caaggtagtc tttggctgga ccagcaaagc caaactggct
     5521 gaggaagagg gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag caccgtgggc
     5581 tgatttacca atgatcgtca ccttgtattt gccagcttct tcttggagtt ctcctctaag
     5641 tttgtgttct gcaacaaagg catctagttt agcttgcaag tcagccaaat cacctgaaac
     5701 gactgctgtt gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa agctgtgaag
     5761 acgggcagca cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat ttcctttttc
     5821 accattgatg attggaaatt cagcatctgg tgagaaaccg aaatctggtt tggcaagtcc
     5881 tacgtgctca aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg ttccaacgat
     5941 gaagcgaact ttcttagaag ttggaaggcc taattctttg atgattttca aaccatagta
     6001 gcaagctgtt gtaggtccct tgtcatctga agcaccacgc gcataaaggc gaccatcttt
     6061 gatagttggt gtgtaaggat ctgtatccca accgctacca gctggaacca catccatatg
     6121 ggcaaagatt ccgagaactt cttctccatc accaaactca aaatgtcctg catagttatc
     6181 aacattttta gttggataac catcacggtc tgcgatttca aggaattttt ccaaggcttt
     6241 tactggacca ggtccaaatg gatgttgggc atcagccttg ctatcatcac gttctgagtt
     6301 gatttccaaa aggctaaaca agtcagccaa gaggtcttct ttgcgttttt ctacttctgc
     6361 tgtaaaatca attgctatca ttttttcttc ttcctatctt ttttcgatga tttcatctac
     6421 tggcaagcgg tagcttggtt ccaatttgtc gtctgtgtaa cccactgtga tcaagagttc
     6481 tgggcggaaa cggtctgcga tttccaaaac ttcattaact tttgatttgt caaaaccaag
     6541 gataatattg gaaccaattc cttggtctgt aagagcgaga accaagttca tagcaaccaa
     6601 acctgcattg agtgctaggt agtcgctgac ttgttgttca ttgtagcgtg caaattcagc
     6661 tggcaaattt ttcatgaagt attgaagttg ttcttctgag aaattgttag caccaccaac
     6721 tcgggcaatc ttacgagcgc gtttggcaag gtctgtatct gtaaataggg caatggttac
     6781 aggtgctgat gatacctgtt caaaattgga accataagct aactttgcca gttcagcatt
     6841 tttctcacgt accaccacaa atttccaagg ctggctgttg tgggcgcttg gcgccaaggt
     6901 tgcaatttcg atagccgtac gcacatcttt gggatcaaca ggcttatcag taaaatgctt
     6961 ggtcgcatga cgttttttat ttaattcaag aaatttcata atcgatttcc ttttctaatt
     7021 ctactgcttc cattctacca taatttgaaa gagcttgcag ggatttttca tgattaagtt
     7081 tttctatcac agacataaaa gatatatatt ggtttatcag gaaagtttct gataaactag
     7141 caagtacttt acatttgaat ggagacagta tgaaaaaatt tagcctatta ctagctatcc
     7201 taccattttt ggttgcctgt gggaatcaag ctacacccaa agagactagc gctcaaaaga
     7261 caatcgtcct tgctacagct ggcgacgtgc caccatttga ctacgaagac aagggcaatc
     7321 tgacaggctt cgatatcgaa gttttaaagg cagtagatga aaaactcagc gactacgaga
     7381 ttcaattcca aagaaccgcc tgggagagca tcttcccagg acttgattct ggtcactatc
     7441 aggctgcggc caataacttg agttacacaa aagagcgtgc tgaaaaatac ctttactcgc
     7501 ttccaatttc caacaatccc ctcgtccttg tcagcaacaa gaaaaatcct ttgacttctc
     7561 ttgaccagat cgctggtaaa acaacacaag aggataccgg aacttctaac gctcaattca
     7621 tcaataactg gaatcagaaa cacactgata atcccgctac aattaatttt tctggtgagg
     7681 atattggtaa acgaatccta gaccttgcta acggagagtt tgatttccta gtttttgaca
     7741 aggtatccgt tcaaaagatt atcaaggacc gtggtttaga cctctcagtc gttgatttac
     7801 cttctgcaga tagccccagc aattatatca ttttctcaag cgaccaaaaa gagtttaaag
     7861 agcaatttga taaagcgctc aaagaactct atcaagacgg aacccttgaa aaactcagca
     7921 atacctatct aggtggttct tacctcccag atcaatctca gttacaataa cactcttcga
     7981 aaatctcttc aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacct
     8041 acggctagct tcctagtttg ctctttgatt ttcattgagt ataagatata ctaaaagcga
     8101 tgggatcagc caatcgcttt tttagtttgc attggttatt ttaggaaact cttacaaaaa
     8161 atcaaaaaaa ttcttcacat cctctacata cccatgcttt tctattaagc ttgctaatag
     8221 ttccagattg tgcccctgat agttatcttc acgacgtagt tcttcataca tttcgataaa
     8281 gggaagcccc ttggatttgg caaattctaa ctcagcctcg taatcataag cgactttacg
     8341 aaataggata tttaccaatt ccccatcttc aacctctatc acgttaaaat agggcatgcc
     8401 aatcgaccct ggattgatga tttgttgccc ttgactacca taacgaagca actgcttgtg
     8461 aacatgacca taaactgcca cgtccgtttc cgcatctagc agttggtcaa atttctctgt
     8521 atcattctca actagcaagt caccaccata gtttttgtca ggtaaattat gagagataga
     8581 aaagcgcaat ccgtcaattt ctttcttttc cagcaaaggc aagcttcgta gccagacaat
     8641 cgttgcagga tccattcgct ccatcaaata ctgtgtcata cgcaagagct gaacttcctg
     8701 tgggtcttct aagccatatt gcccatctaa agcctcaagg acacgatcat cccaattgcc
     8761 tcgaacactt gctgtgatag gaaggtcctt tagcagggcg actaagtcat ttgcgcctgg
     8821 accaggaaga aaaatatctc ccagaagcca gtattcactg actccttgat ttttagcatc
     8881 tgcaatcact gcttctagcg ccgtcgcatt gccatgaata tctgataaaa ttgcgatttt
     8941 atggttcatt gtggtttcct tctgtttggt aatctactct ttcttccgcc acttgaagca
     9001 agatttctgt ttcctgcggg ttcaactttc tttgcacagc ctctgctact gctcttggta
     9061 ctccaacttc gacaatctca tccacaccgg cttccttgat tttggtcaga gacttgaagt
     9121 gcctcatgag attttgcttg cgtttaggtc ccagaccatc aatcccatcc aattgagatg
     9181 agaaagaatt tttggagcgc agttggcggt ggaaggtaat ggcaaagcgg tgcacctcat
     9241 cttggatgcg ttggaggagg aaaaattcct gagaattgcg agacaagtcc accacctcaa
     9301 gcggatctcc aaagagcagt tcatgggttt ggtgcttatc attcttttgc agacctgcaa
     9361 ttggaatatc caagcccagt tcttcttgga tgacttgctt agcaatattg acttgacctt
     9421 gccccccatc aatcacaatc aaatctggag gagtcaaagc ctcacgctgt actcgaccat
     9481 agcgtctgcg aatgacttct ctcatactag catagtcgtc cggcccaaca acggttttta
     9541 tcttgtactt acggtaatct tttttacttg gcctgccgtt aacaaagacc accatggctg
     9601 aaacaggact ggtccccatg atgttggagt tatcgaagga ctcgatgcga actggagtcg
     9661 gaatttggag caaacgtcct agattttcaa tagctccttg ggtcttttcg actgattttt
     9721 ctagcaggtt aaatttctgc tccagactaa cacgtgcatt ttttatggct agattgacca
     9781 gctgtttttt ctctccacgt tggggtttga gaatcttggt atccaccaaa gccttgacag
     9841 cttcttcgtc aatatcctgc ggaatcagta cctcattggg aactaggtga gatttttctt
     9901 gatagaattg tcccacatag gtcaagaaat cctcatctgg atcattgaag taggggaaga
     9961 gattgacatc gcgctcgatg agcttgccct gacgaacaaa gaaaacctgc acacacatcc
    10021 agcccttatc cacatagtag ccaaagacat cgcgattttg gagatcctta gccatgaccc
    10081 gttgcttggt tcgaagtgtt ccaatggcct gaatcaggtc acggtattcc gctgcccgtt
    10141 caaactccat actttgtgct gttactgcca ttttactctt gagatcatcg atgattttgt
    10201 catcctgacc tttcagaaaa tcagacacct cctgggccat ggacttgaaa taggcctcgt
    10261 cattcttaca gatggtgtgg gccatacatt ggccgatatg gtagtaaaaa cagaccttag
    10321 agggcgggtt ggtacatttt cgaaaaggga aaatcctatc tagaagtcgc ttgatttcat
    10381 tggctgcccc cacatctgga taagggccaa aataaagacc accgtccttt ttgacctgac
    10441 gagtaatgat aagccgtgga tagtgctcat tggtgatttt gataaaagga taagacttgt
    10501 catccttgag catgatattg tacttgggct tattttcctt gatcaggttg atttccagca
    10561 gaagcgcctc aatattagac tccgtaacaa taaattcaaa atccacaatt tcagacacca
    10621 aggcctctgt tttggtatca tgacttccac ggaaataaga cctcacgcga ttacgcagat
    10681 ttttagcctt tcctacatag ataatggtgc cgtttttatc cttgtaaatg tagcaaccag
    10741 ggctggtcgg caagagctct agttttggtt taatcaagtt gttcatagtt ccattatagc
    10801 aaaaaagtag ggaaagatag taccctactc attagtctca tatatttttc ggaggtttgc
    10861 aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag acttctcatc
    10921 tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga caaggcgttc
    10981 ataggaatag ccatagtatg gattggacaa ataataatga ttcaaccgca ccgttacgga
    11041 caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca caggagtgcc
    11101 tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca cgagttcaaa
    11161 gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct cttgaaagcg
    11221 tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtgcccacc ttccttcaga
    11281 atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct cccattggtc
    11341 aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc cttgaaaatc
    11401 cccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa ctatccaaac
    11461 cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac gaaaaagcca
    11521 gcgcatgtct ctccaccttt ctagcaaata agaattattt tactaaaaga agctaaaaga
    11581 aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta actggatagc
    11641 tttgtatttt aaaggcgatg gatggtaacg gaaagtaccc gctttgcgta caatatagcc
    11701 attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc cttgaatgcc
    11761 taggaaattg tatttaggta ttccacgttt tatgctttcc aacataacat atttttgaag
    11821 cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga gataagtcgt
    11881 ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt ctccatattt
    11941 ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt gactagaata
    12001 ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat caagtcgcaa
    12061 cttgtccaag ttttcttcta gtttattttg ttcaccttgc aatttgctca tatagtccga
    12121 aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat aaaaatgctc
    12181 ataatattct aaacttttat cactatattc tctacgttca gaggtttctt ttgttatatt
    12241 cttaaaaatc gatagttctt cacgttttaa ctttttcaac cgaatgccaa aggtttcagc
    12301 ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct tttcagttaa
    12361 ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac ctgttgttaa
    12421 gccatcaaat tgataaccta aatcagtcaa atcttgaata atactttttt tctcagcatc
    12481 tattggatta ccttggctat caaaagtttg ataagtttca tagggtttta caagcaactc
    12541 taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg gaagagcatc
    12601 ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca gcatgggcaa
    12661 gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa gataaacaat
    12721 tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa aggaacgaga
    12781 agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta gtgccatata
    12841 cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt cttaacagag
    12901 gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc gttggattaa
    12961 atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca cctaaatttt
    13021 gccagatcat acctcgctca aaggcatagc gagccgtttc ataccatgtt aaaattggtg
    13081 cattgtaacg tttaaaatca tcatccatac cagcatatat attgacagag gtagtaccaa
    13141 attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct atatattcct
    13201 gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct tctacttttg
    13261 aagttcgagt cgactcagta aacgtctctt ccaaggctct atttttcgct aactgttctt
    13321 ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag gccttgtcct
    13381 taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc tcttttcgct
    13441 tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca ccatattgaa
    13501 tctcaagccc tttgtttcgt gctgttcgaa tagtctgttt tgttgacttg gaaagtttat
    13561 cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg gtgtctccca
    13621 tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca ataatagcca
    13681 gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg caaatacttg
    13741 ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata gactgaatgg
    13801 caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg atgtaaaaca
    13861 ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt aatttttctt
    13921 ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc caagcactac
    13981 tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct aatgtgggaa
    14041 tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta ttactattct
    14101 actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta ctccccctat
    14161 gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt agggttgtta
    14221 aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagcg ctatggctat
    14281 aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg gcttcgtaca
    14341 agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat tttttagcca
    14401 gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa acacctctcc
    14461 agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag ctgagggcac
    14521 ctgaaaaact agctgcatga gaaaaacgat ttgtcgcaag agccagtttg aaacagccgt
    14581 agcctcccat agaaagacca gctataaagg tcttttcacg cttgctagtc atattaggga
    14641 agaagcgttt cagaacctgt ggcaattcct ctgctagagc cgtgtagtag tcaaaaccat
    14701 actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg agattagttc
    14761 ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt ccagacatcc
    14821 cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact cgattggcat
    14881 cagggtagag gacattcatc ccccactcca tatccaatac ttgtgagtaa tactcgattt
    14941 tcattactgc catgattttc tccttctatt tttctataag aaaaagccga aactcgactt
    15001 tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa tagctggacg
    15061 acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc ctttaagatc
    15121 tgcccagtca aagtcatctc cttgaagata atcttctacc gtttggttaa tcaattctga
    15181 actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg tgtgaacacg
    15241 agctctagcc acaattttct tctcacgacg gttgactgta atagccacga tgaaaattcc
    15301 atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac caatggcatt
    15361 cccatcaatt aagatatctc ctgctgaaac cgatccagct ggaacaaagt ctccattctc
    15421 gtaagccatg gtcgtcccct ttttaggaat gaagatgcgt tctggcaaca tcccaactgc
    15481 catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag ggaagaggta
    15541 cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt gccctgatac
    15601 atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca tattttctac
    15661 acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga ccaggtcccc
    15721 atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc cattgatagg
    15781 ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc gagacatatc
    15841 tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac gaatcgctgt
    15901 gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg ttttatccgc
    15961 agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa cgatgatacg
    16021 accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt cactagccac
    16081 ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc cgtcacgacc
    16141 aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt ggtcaaattt
    16201 gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc ccagactctc
    16261 tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat caatctccgt
    16321 attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc ctttgacaaa
    16381 gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag cctctgccaa
    16441 gagataaggt agagcaccaa tcgcatccgc atgcccgtgg gtcaagaaaa ccccagcaat
    16501 acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga cccctaattg
    16561 ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc caatttcagc
    16621 aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac tgatattact
    16681 catttttcct ccaaaatctt agtttatctt gattataggg caactctacc ctcttattct
    16741 aaaagttcta atactttcag ccgaatcttt tcctaccatt ataccatttt tttgatgatt
    16801 ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc ctaacttcta
    16861 ctctttttcc atcaaaaaat cataaatttc ttgcaccata cccagcgcca tcatttcttg
    16921 gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct cccgctttgg
    16981 cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta gttcttcaaa
    17041 tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag ccaaatcttt
    17101 cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca atttggcaaa
    17161 ctgatctcta gtcccataac ctgtcagata ataggccttg tcaatatcat ttttgaaata
    17221 gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat cctctggaat
    17281 gttttttacg acaatagctt cactagccgc aagatttggc agttctccag gaaaatccaa
    17341 gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa gttgaacacc
    17401 ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc attggttgac
    17461 agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg cccatctgcc
    17521 ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca gctttagatg
    17581 ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga tataaaaaat
    17641 aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga ccgtttccaa
    17701 gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc caccagcatc
    17761 tgcacctttt tcacgaacat aatcttccaa aacctgagat aaatctgaga gttgctcaac
    17821 ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgataaaga ggtctcgatg
    17881 gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc ccttggcacg
    17941 accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata aacgaccagc
    18001 cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa ccttcttctc
    18061 aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct tgcgctcttc
    18121 gtttttctgg tgaatcataa aggcaatctc atgcgcttcc tcatcatcaa atccagtcaa
    18181 caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac gaggagcaat
    18241 ctggaaacca accgtttctt ctgttacttc gttggcagca atcccagcca tgtccagcat
    18301 ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt gaactaagat
    18361 acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga ccaaatcaag
    18421 caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa ctccacaacc
    18481 agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa tagcataagc
    18541 atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta ctcccataga
    18601 ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca caatcaagga
    18661 aattccttct tgctcgataa agtatttata aacactagca ttagggccat agccatcggt
    18721 aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac tttccttcac
    18781 aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa tattttcccc
    18841 ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga gcagataagc
    18901 atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt ggtcctgaat
    18961 ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct tggctatctt
    19021 tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag gtgttatcaa
    19081 aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt tagacgtttt
    19141 ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga atagtacacc
    19201 tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt gtcctgttct
    19261 tatttcacta tagtgaattt tttcagatat ggtttgacaa gaacattctt ttattgtaga
    19321 atcgtgttat aaaatctaac acaaaggaga tctctcatgg ctttagtaga atttaaaaac
    19381 gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg ttttgaaaaa
    19441 ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct tatccgtacg
    19501 atcaatggtt tagagactgt tgacaaagga agtctcctag tcaatgggca ccaagttgct
    19561 ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt ttttcaacat
    19621 tttaaccttt atccacacaa aactgtgtta gaaaacgtaa cacttgcacc cattaaagtt
    19681 ctaggaattg ataaaaaaga agctgaaaaa accgcccaaa aatatctgga atttgtaaat
    19741 atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa acagcggatc
    19801 gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga accaacatct
    19861 gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact ggcgcatgat
    19921 gggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt tgcggaccgc
    19981 attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga taactttttt
    20041 gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa ccacgaaagt
    20101 gacaaagtca aataaggagg cgcctatgaa aaaaaaattc tttttatcag cattattgat
    20161 tagccttttc ggccttgctg ctgccaaacc agtccaggct gatactagta tcgcagacat
    20221 tcaaaaaaga ggcgaactgg ttgtcggtgt caaacaagac gttcccaatt ttggttacaa
    20281 agatcccaag accggtactt attctggtat cgaaaccgac ttggccaaga tggtagctga
    20341 tgaactcaag gtcaagattc gctatgtgcc ggttacagca caaacccgcg gcccccttct
    20401 agacaatgaa caggtcgata tggatatcgc gacctttacc atcacggacg aacgcaaaaa
    20461 actctacaac tttaccagtc cctactacac agacgcttct ggatttttgg tcaataaatc
    20521 tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc atcggagtcg cccaaggttc
    20581 tatcacccaa cgcctaatta ctgaactggg taaaaagaaa ggtctgaagt ttaaattcgt
    20641 cgaacttggt tcctatccag aattgattac ttccctgcac gctcatcgta tcgatgcctt
    20701 ttccgttgac cgctctattc tatctggcta cactaataaa cggacagcac tactagatga
    20761 tagtttcaag ccatctgact acggtattgt taccaagaaa tcaaatacag agctcaacga
    20821 ctatcttgat aacttggtta ctaaatggag caaggatggt agtttgcaga aactttatga
    20881 ccgttacaag ctcaaaccat ctagtcatac cgcagattaa ggaggatacc ctatgacaga
    20941 tttatcatct tggacagcct attttcagga ttttggacaa tttttcaatg gtttcctctt
    21001 tactcttgcc ctagcgattg gatcctttat cctcgccatg gtcttaggaa tcttctttgg
    21061 tgccatgtca accagtaaac gtccaatttt acgcatttta gctcgcatct ttgttgaatt
    21121 ttaccaaaat actcccctct tggtgcagtt tgttattgtt ttttatggcc tacctcttat
    21181 cagtgaccat atcatcatga ttccaattta ttggacagcc gttctctgcg tgggactcta
    21241 tcacggcgct tatatcgctg aggttattcg ttcagggatt cagtctattc ctagtggtca
    21301 gatggaggcc gccttgtcgc aaggttttac ctatatcagt gccatgcgct tgattatctt
    21361 gcctcaggcc ttccgcatca ttctccctcc attgaccaac caaattgtta acctcatcaa
    21421 gaacacctct actgtagcta tcatctctgg agtagacttg atgtttgtga ctaagtcttg
    21481 gtcggctctc aacggaaact atatcccagc ctttttaggt gctgctcttc tctactttgc
    21541 cctatgcttc cctgttgccc agtttggtcg caagatggag caagccaaca aaaaagccta
    21601 ttcactttag gaggttacta tggaatctat tttagaagtt ttaaccccag ataacctagt
    21661 ctttatcttt aaaggatttg gcttgaccct ctatatttct ctgattgcca tcatcctctc
    21721 tactatcatc ggtacggtgc tagctgtcat gagaaatggc aaaaatcctg tcttgcgaat
    21781 catctccagt atttatatcg agtttgtgcg caacgttccc aaccttctct ggatttttac
    21841 tatctttttg gtgttcaaaa tgaaatccac accagcaggt attacagcct ttactctctt
    21901 tacatcagca gccttggttg agattattcg aggcggtctc aatgccgtag acaagggaca
    21961 atacgaagca ggaatgtcac aaggcttcac ctcagcccaa atcctctact acatcattct
    22021 cccacaagcc atccgcaaaa tgctaccagc catcatttct cagtttgtta ccgtgattaa
    22081 ggataccagt ctcctctact ctgttatcgc cctacaagaa ctctttggag ccagccaaat
    22141 tctcatgggc cgttattttg aaccagagca ggtcttcagt ctttacatcc tgattgccct
    22201 catctacttc agctttaacc tagcaatttc tagcctgtct catatgctag ccaaacgttg
    22261 gcaacaagct gcagaataat actcttcgaa aatctcttca aaccacgtca gctctatctg
    22321 caacctcaaa acagtgtttt gagcaacttg cggctagctt cctagtttgc tctttgattt
    22381 tcattgagta taaacagcca ctctccagtt caattggaga gttttttgat gagagtagat
    22441 atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac aaattcattt
    22501 acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa aggactactc
    22561 tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc tccccaattc
    22621 atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc cactcgtctc
    22681 ccactactag aaagctggtt tcacggtttg gagaaggtct acaccgtcca caaattcaca
    22741 gcctttctct ccatcatcct actaatcttt cataacttta gtatgggcgg tttgtggggc
    22801 tctcgcttag ctgctcagtt tggcaatctt gccatctata tctttgccag catcatcctt
    22861 gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca ccgcctggtt
    22921 tacctagcct atattttagg actctttcac atctacatga taatgggcaa tcgtctcctt
    22981 acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt actagctggt
    23041 ttttatatca tttttctata tcaaaagatt tccttcccct atctaggaaa aattacccat
    23101 ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag acctttcaac
    23161 tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga aagtgctccg
    23221 catccctttt ctatctcagg aggtcatggt caaactcttt actttactat taaaaattca
    23281 ggcgaccata ccaagaatat ctatgataat cttcaagccg gcagcaaagt aaccctagac
    23341 agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg gattgctgga
    23401 ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt agataaacag
    23461 gttcacttct actatagctt ccgtggagat gaaaatgcag tctacctaga tttactccgt
    23521 aactatgctc agaaaaatcc taattttgaa ctccatctaa tcgacagtac gaaagacggc
    23581 tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat gtgtggtcct
    23641 atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa aacagagctt
    23701 atttacgaag gattcaagtt caaataagta atcatactct cctgggattt cccaggagag
    23761 ttttttatag ccaaatgaaa taagacagga acgatggaat tttggcattc aaatcaattg
    23821 ataagaatgt tttatagtgg agtgaaatag gatacgaaca aattgattag gaaaatcaaa
    23881 tgaatttata gaaatctttt agcagttatg ttgtcctatt ctagtttcaa aacgctatag
    23941 aagcagcatt gtgctagtct agattcagtt tactatacta aaacgagtag cttgaaatca
    24001 aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta tgctttacct
    24061 tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt tacaccgtca
    24121 gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc gtttgcttcg
    24181 tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc tgtgttaacg
    24241 ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg aatacctgat
    24301 ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg caagtggtca
    24361 aggtcaagac cttcccagtt tactgggtaa ggaccgtgga tgttaccgat accagctgcc
    24421 aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc caattcacct
    24481 ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc tactgagata
    24541 cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc ttcaactgga
    24601 aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc aagtgcatct
    24661 tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat tgattcaaca
    24721 aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc agcacccatt
    24781 gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat agcttgagtc
    24841 cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg ggctgcttgg
    24901 acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat ttttatgggt
    24961 catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt ttttcccgca
    25021 gtttcgattg attttcttct aactccatct atgtaaaccc tttctctccc tagtcttgga
    25081 cgacttttgg aaaatctata aagaaggtta aacgattctc ctccatctcg aaacgataag
    25141 ctaatttttc atgttctaat agactcttaa ccacaaagag ccccatacca gaccccttga
    25201 ccttgcgact ggcattgtca gaaaaagact gggctagttt ttcttgttcc tctgagctac
    25261 agctattttc gataaaaagt tctccttctc tttctccaat tcgaactaag ccacctggaa
    25321 cagagtgctt aatggcattg ctgatgagat tagaaagaat caacttcata actgatgggt
    25381 ttagataagc ctgctgatgg gtcaaactat tgtctatctg gagctctctt tccttggcta
    25441 gcaaggcata atctttgacc agattttgcg tcatctggag gaggtcaatt gtttccctat
    25501 catctcgcaa ttcctgcaca gaagagaggg aaagtatctg cagaacatgg tgattgagtt
    25561 catccacaat ccccaaggca actcccagat actggtctct atccttataa cgaccgatat
    25621 tctctctcat attttcgatt aggattttca aactagccag cggtgttttc aattcatgag
    25681 aagctcctcg taggaattcg accttcatct tctccagctg gagaatggct tcattctttt
    25741 catgcaagtc cgcaataaca gtcaagagat gctggtagag gctattgatt tgttccttga
    25801 gattacctat ctcatcctta gaatccacgc gcaatcgcac ttgggcatcc aggtacatca
    25861 tccgacgagt cacccgcttg atttccaaaa tcggtgcaac aatagtccga gcgtagatgt
    25921 aggccaccaa gagggaaatc agaaaggagg ccagcaaggt atagggaaga aactggagac
    25981 tgatttgctc cgcttccttt tgtaaatcca tggaagctag aaactggaga atcatagtac
    26041 caccgtcttg cgttttcacc tcgcgctcct caataaagag agaggttgtc tggcggtctg
    26101 tgtccagagg aagactgtcc ttgacttcta acttgtcctc ggtcatctca cctttgacgg
    26161 tccccttgat atcactagtc tgggaataca agtctaacac ttgctcgata ctctgcctat
    26221 ctttcccttc tagggactgg gcaatggctg ttgccttttg accaatggtt tcctgacgat
    26281 gactcagata agtcgaagga aaaagaaaat aaatagctaa atgaaggcag ataaccagaa
    26341 cactaaatat cgagaaggta tagataaata tctttgcaaa taaacctgtt cgtttcattt
    26401 tcgctccaat ttataaccaa cattgcgcac agtgaggata caatccaagt ctagcttttt
    26461 ccgcaattcc ttgatataaa catcaataac acggtcaaag ggaacctcat ctgtcgcttt
    26521 ccagacggca tcgataatct gagatcgagt caaggcccgg ccttcatttt tcactagata
    26581 gtccagaatt tccaactctt tggcattgat aggcacttct tgacctgcga tgcttgcact
    26641 gtagctttca aagtccacct tggtatcctt gtaagaaaag attcgtcctg tatcgtagta
    26701 gcgcttgaaa atcgcgtcca ccctcacttt taaaagggag agggagaaag gtttttccag
    26761 atagccatct gccaaagagg caaaggcact catcttgtat tcctcatcct gaaaagctgt
    26821 caacatcaag acaggaacct gactggtttt acgaatctca gctaggactt ctaagccgtt
    26881 gagcttgggc atctggatat ccagtaaaac cagggccacc tcatagctag aaaattgctc
    26941 cagagcttcc tgaccgtccg ctgcctcaat agtttcatag ccacaatccg tcaaataatc
    27001 actgaccccc tcacggatca tctcttcatc ttctacaatt aaaattttca tactttaact
    27061 gctctctatt ttttattttt cttagaataa atacctactc tattttctat tatagtctct
    27121 tgctggcctt ttgtctgtaa gtaactgacc actagataaa acgttgtgaa attcctttct
    27181 cataaattcc ataactttag tatattatat ttaagcacta aagtacaaag aaagcaactg
    27241 aaagcaatga ttttcaccac tgctttcaga tttattttga attgttaaat agccattcct
    27301 atccactatt cttgaataga aacacaagat gcaatcttta ttccagactc attttttcaa
    27361 atttattcac catccagcaa gagttctttt ggttgttttc taaggagatt gcttgaagca
    27421 agcgccataa cgagaaccac tagaaccaag gcaaggacaa aaatgatgat aaagtctgat
    27481 gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa agccatctac ttctgcacca
    27541 ccaccaaggt tagaggcttg agccgcctta ctagcctgtt tggcaacacc tgaagtcaca
    27601 ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa gtaagcagaa
    27661 actagagcag ggatagcaat caagatagat tcggtgatga attgacccaa gatacttgcc
    27721 tgcttgaggc cgatagagag gagaattccc acttccttgc gacgggcgtt gatccaaagg
    27781 ctgagcaaga gggcaaggag gagaactgag aagctcaagc taccccagaa gaggaggttg
    27841 gccatcttgt acataccaga gatagattgc tcaagagctg ggtagttaga ggagctcttg
    27901 acgagtgtgt agctcttcca gttgatacca ctgatgccat tcaactcttt cataacatca
    27961 tccaagttct tgtctgctgt tacaaagaag gttgcgtccc cataaatggc tgtgtcttct
    28021 gtgtatccat aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt ttcgtaaagt
    28081 tcttgtgagt aggttactgc tgacttatta tgaccatcaa agagtccctt gattgtcact
    28141 tcaactgttt ccttggctcc tttttcatta tctgcatcgt agatattaga gtccagttta
    28201 accttgtccc ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa gaggatttta
    28261 tccttgtcgt cgttggttaa gtgctctcct tcgactagtt tataagaacc agagacaaac
    28321 ttgtcttctt tagaggagtc attgacacct gtaatcatca agctacttcc aaaacgtttg
    28381 gcacgatcag cagtgagatt cttcttggtt tctggcgttt caatcaggtc atatccagtc
    28441 aaatctccga tagcgttgat acgtttgaca taagactcga tggccttgtt ttcggtgatt
    28501 tttttgatgt cttcaccctt gatattccca gcaccacgag gcgttccttg gttgacgcga
    28561 cgattgattt gcatggagaa gctattggtg atatttttaa aggtctcctg agaagccttg
    28621 gcagtagctc ccttgattga caagccgacc aaactcaagc tcgccatgag gagaataatc
    28681 aggaagatga caatcgattt gaaaaacttc cttgtaacat aggcaaatgc gttgtgtaac
    28741 atagattccc tttctagatt ttgttttaat cattctatca aaataagctc aaattattta
    28801 ctagtattgc gcgtttcagt cagtttctta tcctttaatt caagtgtaat atctgacgct
    28861 tgtgccactt ctttactgtg agttacgaca atcacacatt tacctgtttt ctgggcaagt
    28921 gatttgagta gttcgacaat atctccagca gttttaggat ccagatttcc tgttggctca
    28981 tcagctagaa taactggagc ttctgagacc aaactgcgag caatggcaac acgttgctgt
    29041 tgaccacctg ataactggag aacattccgc ttgatctggc tttcatccaa accaagctca
    29101 agaagtgtat tcttgcttgc ctttttgttg accaatcgga tattttccag cggagaaaga
    29161 taatctatca agttataatt ttgaaagacc agggaaatat ggtgcatgcg atggtaagaa
    29221 tagcccttct tacgaatatc ctctccttga aaaaggatag aaccttcaac aggactatct
    29281 agaccagcaa gtagggacaa gagtgtggat tttcctgctc ctgactcccc aataatactg
    29341 taaaattttc caggttcaaa attataatcg atctgatata ggactgcttc agcagtattc
    29401 ttataacggt aggtaacatc ttgtaattgt aataaagtca tgatttctcc ttcttaacta
    29461 atagatgata aaatttcttt cggtgatttt ctaaataaga ataggaaaca aagggctaca
    29521 gataagcaac taagcagaac tagaaaaaca taggattctg caaaagataa gatgctagtt
    29581 gataaactgc ttgctttggc tagtgtatct tgtaagcttg cctgatctcc acttgctagt
    29641 agagtttgga gtaggtaagt tgtgattccg tttcctgcaa caaatgctgg aagcaaagct
    29701 ccaagagata ccaaaactac ctctaaacag aattgtagga agatcgagct cttgcctttt
    29761 ccaagtgcaa gtaaaatccc cacttcatag acccgttctc tcaaccagag agacaaaacc
    29821 agaattaagg ctccagctcc tgctatcaac atcccataaa ggaagatggt caggaaggtt
    29881 tggaaagttg caactgagtc tttgatttgt tcaaaagcct tgttttcctt ttcgacttgg
    29941 tagccttgat tttccaaggc caagttttct acctgcttca tgagtccgtc catttcctta
    30001 ggattttcta catagaagcg tgctgcactg acttgagctt cactattgcc caaaagggtt
    30061 tggctacttt catagtctgt aaagacttga ttttcactga agtcagaaga caagcctgtg
    30121 aatttctctt gttttttacc agaaaagatg ccaataatct caaactctac tgtttgtcct
    30181 tttccagatt cagactgacc agcatccaag ccaatcttgt catgaagtga aagaccgttc
    30241 ttcttagcca attcttcgtg gataaggatt ttcttggaat cccctttttg aaggtgtcgc
    30301 ccttctttta gattgaaagc cgaactggta aaggttacat ccttggatga atcctcaaga
    30361 gccgttaagc taaccaagtt attgtctgca gctgataaat catcacgctc cacgctctgc
    30421 tctccagtca ctgcttcctt gtcttttagt tttgcgaccg tctcaagttc aggagagaca
    30481 ttttccagcc ccttaatctt gcttacagat gctaggtctg acaacttgaa tgtctgacca
    30541 ttctctatct tcttaataga aaaagatgta ttgagtgatt tataaagatt gctttctact
    30601 gttttgttgg acttcatcag agtcaaacag gctgaaattc cggccaataa gaccaataaa
    30661 atcagaaata aaataaaact tctcagtcgc tttctgctga cataagccca agatctttgg
    30721 attggattca tttgtcacct ccatatttgt aagactatta taaaacccaa atatgaaatg
    30781 tttatgaaat acgaaaaaaa aatatcgagt aggggataat ctctagcccc tctcacacca
    30841 ccgtacgtgc cgttcggcat acggctgttc aactaacttt taacgcatgt cgttcaaggt
    30901 aataatccaa acacgaaacc agtccacgtt tttcaaggac tggttttgat atagcacgtt
    30961 taagtaccga cttctgagct actatagtag attgaaacta gaataatata cctctacttc
    31021 taaaatattg ttagaaatcg atttgacttc cctgatcgat tcgtcctatt cttatttcat
    31081 tttaatataa ttgatagtgg tcgccccagc cagatacctt atctgctatc catttaggaa
    31141 cccctaactt aagcaatccc cataatcgtc tcgatttctt cttccattgc ttccagataa
    31201 tcactcgtag gcgagtacgc aagcgctcat ctatgctagt gactatactt ttcatattta
    31261 taattcattc ctttcgtttc actcaaggca caacacagaa tgaaaaagtg ttgtgatctt
    31321 tattttgttt tataataata gtgagaaagc ctatcactac tacaaatcac ggggaggtga
    31381 ataagtgagt ggtacagcca ctacctcgca tattttgtca catcatttaa cggtgcataa
    31441 taagttgtac catctgaata agttgctaca atatcatttg catgctctcc ttcaccttta
    31501 gcaaaggttg gagctcctgc tggatgattt ttatttgcct ctttcaattt ttcaataatg
    31561 gcattttttt ctgtatcttt tatattatca ggatttttca ctaagatttt gtctggatat
    31621 gtcggtttag cagaaacaat ttttactgtt atttcttttt tattcgaagc acttgtccag
    31681 tttccagcat tatctttagc atttaatttt acagtaattc ctgaactagg aacttcagta
    31741 gcaggttgat tatcaacatt attcaacttt aatttcaaaa gagctgttgc atcagacgtt
    31801 ttatcaatcg ttgtatataa tgatgaattg ttattataac cagtttcttc atatttagct
    31861 gtttgtgagc tacttgaaac agaactgaaa ttatgcccac tacctccctg attatcttca
    31921 atgcttacgt ctaaatgaac ttccccacta ttatttggct tagcaacaac tgttatagta
    31981 aaataacata aaatttgcat aaatagatta gggaaatcaa agcaacttct aggaatgttt
    32041 tatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgacgtac tcaagtacag
    32101 cctgcggcta gcttcctagt ttgtactttg attttcattg agtattatca gtcacagtgt
    32161 actttcccag catcaagcca ctataactct gcacataaaa atggagaaga tggcaatcct
    32221 cttctccaaa tattaacttc tttacaaacc aactatagtt gacaaagaac ctaaaatcaa
    32281 ttgataacac aaggtcaggt cggtcaactc tttcaactga agccctgtca actcttccca
    32341 tttatcaatc ttgtattgga gagaattgcg gtgcagatag agttgctggg ctgttttagt
    32401 gagaacagca ctattttccc aaagagagag aatgatttcc tgaatctgat cttgatccaa
    32461 aatcatctgg tgtagacatt ctttaattgg cttcaagtcc acgagtcttt ctcccatact
    32521 ccaaagatag agctgagaaa aagtatgaac accttggtga ccctgacgcc accatgtctt
    32581 gaacaaatcc cgctcagctt tgattaagtc tgatagggct tgatgtcctg tctgagacca
    32641 aacctgaccc aacatgatag aaagacgaag tccaaaatca tactcaaccg cttcaatcgt
    32701 atcacttaaa atatctctta cagaagtgta tttgtcttgt tgaagcacga aaacataatc
    32761 ctgagctccg acctgtagca ctgtctgaca attcggaaaa agagtccgca tcatatctag
    32821 ccaagaagtc agattttcct gctgaaaata agaaagatgg caataaacca actgaatctt
    32881 tttaaaaact tgcggtgcct gtcccttgcc ttcaaccaga taggaatacc aagggtttag
    32941 cgaacgagcc tgctcctgct gggtcaaaag ggcaaccaac tgcttttcac gctcgctgag
    33001 cccagcttcc tccagcaaaa tccactgctg agaagctaaa gggagcgtga gatagccctc
    33061 tttctctact ggttggtctg aaatccgagc ctcaggaaac cagtcttgta gttctttttc
    33121 cctcatgttc tagccctcca ctttttggat gcaccatgaa accaaactct caagacgttc
    33181 cagattctca gtcatatgga gatagcccat aaccgcttca aatcccgtgg acatacgata
    33241 agtcacgaca tctgcatttt tagcctttgt gtggctattg gtattgcggc cacgtttgta
    33301 gatttcttct tctttttccg ttaggacctg ctcctccaac atgagagcaa tcaggcgagc
    33361 ctgagccttg gctgacacat acttggttgc ttcttgatgg agtttattgg gtttggtcat
    33421 acctttgagg atgaggtggc ggcgaatata catagaatac accgcatctc cctcaaaggc
    33481 tagcgcaatc ccgttaatga gattgacatc aatcacgtgt ccacctcact ccatcttttg
    33541 tatccaatag tttaatgcct tgagcagcca gttggtcacg gatttggtct gctgtctcaa
    33601 agtctcgatt ggcacgcgcc tcttggcgtt tttgaatcaa gtcttcaatc tctgcatcca
    33661 aaacttcctc aacaaagaca attccaaaaa tttctaacat atctgcaaga gcttgcttga
    33721 cacttgcatc atagttccct gagttgatcc atttggtcat ttcaaagaca actgtgatac
    33781 cgttggcagc attaaaatct tcatccatag ctgctacaaa cttatcttta aagttttgta
    33841 actcttgggc atccacgttt cctgtaaatg gttgttcgta agtattcttc agatacttga
    33901 gattggtctc ggcatcgcga actgcctttt ccgtgaagtt gataggctta cggtagtgct
    33961 gggtcgcaaa gaagaaacga agtacttgcc catcaagagt tttaagggca tcgtgtaccg
    34021 taatgaagtt acccaaggac ttagacattt tgacattgtc gatattgaca aagccattgt
    34081 gcatccagta gttagcaaaa gccttgcctg ttttagcttc agattgggca atttcattgg
    34141 tgtggtgcgg aaattctagg tcagctccac caccgtggat atcaatggta tcacctaaaa
    34201 tctctgtcga catgactgaa cactcaatgt gccaacccgg acgtccaggt ccccaaggac
    34261 tatcccaaga aatctcacct ggtttggaag atttccatag agcaaaatct acaggatttt
    34321 ccttacgagc cgtttcttca tcggtacgac ctgaagcacc tagatccaaa tcttccaagg
    34381 ttttattagc caatttggca tagttgtggg atttttctac acggaaatag acatcccctt
    34441 gactctcata ggcaaagcct ttctcgatca agtcttccac aaaacggatg atgtctgcca
    34501 taaactccac tacacgcgga tggcgagtcg caggtttcac gcctaaggcc gtcacatcct
    34561 cacgaaaggc agcgatgtac ttatccgcaa cctcctgagg cgtgatacct tcttccctgg
    34621 cacggttgat aatcttatca tccacatctg taaaattgga aatataggca accttatacc
    34681 cacggtactc aaaatagcga cgaatcgtat caaaagctac cgtcgaacgg gcgtttccca
    34741 cgtggatata gttgtacacc gttggcccac aaacatacat cttgatcttg ccgtcctcaa
    34801 tcgggacaaa ttctcgcaaa tcacgagaca tggtgtcata gattttaatc ataaatcata
    34861 atcaggaaag ctgaaatcca agaacaatta gtttcatcac taaaagttca agtaaatttc
    34921 agtccgaata tctctacact tcggaatccc ttgctccttt ctcattcaga taaaccacct
    34981 gagtctgttt gacaaagcca attttttcat acaaacgttt ggcacctaca ttgctatctt
    35041 ccactgcaat ctgaaattcc ttgtcatttt gctcaattag ttggttgacg agggattttg
    35101 ctaagtagct tccatagcct ttcccacgtt caggttccga tattgctaaa ccgtagaagt
    35161 aattcgtatt agtcgataaa tctaccgtgc aagtcccaat aacctgaccg tcttttaaca
    35221 aaatatataa gcgactttct ggatccttca gagcttcagc gacatatcta tccacaactt
    35281 ctctcgattc atgttcctct gaaaatgcct gaaattttaa ttgactaatt tgatcctgat
    35341 acgaactatc tgctaacaaa acttcaagat gggaaacatt tgctaacgga taaggtcttc
    35401 tatccttacc taaccaagtt tctgtctctt catcctcgat tagtccccag ttactggcaa
    35461 agtcaggatg attctctaaa aaaatacgtt ctgtctgaaa agtgactgac cgaatgggga
    35521 aagaagctat ttctctctca aaactagtaa acaatgcacg cgcaatcccc tgacggcgat
    35581 gacctggatg aaccagtatc gttacttcta catcttggtc atctgcatag acagttaata
    35641 aaccaacaag ttcgcctttt tcataataaa ggaaaaaggc gggcatgttt gggtcaaaat
    35701 taagcatgtt agagagatag ggatcgcgat aggtaccgtc atagttttgg caacagttaa
    35761 ttactttttt cgcctcagat agctcctctt ggcttaactt gtttcttgct tgaatcatat
    35821 aggtatcctc tacaaaccag acgatctgtg actggcatct ttagcctgct cgagtttatt
    35881 gacataatac tctcgttttt cttcgacttc gtgaatgaca ggctcatctt tcttaccatg
    35941 aagacggaca atcttggccg gaataccgac aaccgtcacg tcactaggta catctgctac
    36001 gacaactgct gcagcaccga ccttggcatt ttcaccaatt tccacaggcc cgataacttg
    36061 ggcatgggct gatatgaggg ctccctttcg tacagtcgga tggcgtttgc cacagtcttt
    36121 ccctgttccc ccgagagtca ctccgtgata gagaagaacg cctttttcaa caatcgctgt
    36181 ctctccaatc accagaccag aaccatggtc aataaaaaca cctgaatcaa tctgggctcc
    36241 tggatgaatc tcaatctgag tccaaaagcg ccaaaactga ctgtacatac gagctaatag
    36301 tttgaagccg tgcttccaga gaaaatgcga gagacggtgg gccgccaagg ccttgacacc
    36361 tggataagtc agcaaaacct ccaaagtggt gcgggccgct ggatcatttt cttttacaat
    36421 atcaatggtt tcgcgccacc accccataca tttctccttt tcttattctg aatcttttgg
    36481 tgtttctgta aattctttct taggtttgtg atccttttga tgacgtgggc ggtgagggcg
    36541 ctcagacttt tcaccttttt catcatgctc aggttttggc ggacgaggta gaagagcctt
    36601 catagaggca tcgatacggc ctttttcatc aatcttgata accttaacat caacttcatc
    36661 cccgatttct accaaatcct ctacacgatt ggtacgagtc caagccatct cagagatatg
    36721 aacaagggca tctgtcttat caaagaggtt aacaaaggca ccaaatttct cgatacgaac
    36781 gactttagca cggtaaactt catccacttt ggcttcacga accaaaccag caataatttc
    36841 tttggcacgg ttaatagcat cttggtcact agagtagata gacacatttc cttcttcgtc
    36901 tatatcaatc ttaacacctg tttcagcgat aatcttgtcg atggtttctc cacccttacc
    36961 gatgacaatc ttaatcttgt ccacatcaat cttgatcgta tcaattttcg gagcagttgg
    37021 agccaattct ggacgaactt ctggaatggt tgcttcaatg acatcaagga tttcaaaacg
    37081 cgctttcttg gcttgagcaa gagcctccgt caagatttct gcagtaatcc cttgaatctt
    37141 gatatccatt tgaagggctg taatcccatc acgagtacct gcaaccttga agtccatatc
    37201 tccaaagtga tcttccaaac cttggatatc tgtcaatact gtgtagttat ttccatctga
    37261 gataagtccc atagcaatac cagctactgg cgccttgatt ggcacaccac cagccataag
    37321 ggcaagagtt cccgcacaga tagaagcttg agatgaagaa ccgtttgatt ccaaaacttc
    37381 tgctactaga cggatagcgt atgggaattc ttccaagctt ggcaagactt gagcaagagc
    37441 acgctcacca agagcaccgt gaccgatttc acgacgacct ggcgcaccgt aacgacctgt
    37501 ttcccctaca gaatattgag ggaagttata gtggtgcata aagcgtttct tgtactctgg
    37561 atccaaacca tcaatgattt gagtttctcc catcggagcc aaggtcaaga ctgaaagagc
    37621 ttgagtttgc ccacgagtaa agagacctga accatgtaca cgaggaagga agtcaacaac
    37681 cgcatccaaa ggacggattt catcgacctt acgaccatca ggacgcacct tgtcttctgt
    37741 aattaaacgt cgcacttctg cgtgttccat ttgttccaag atttcagcca catcacgcat
    37801 aatacggtca aattcttcgt ggttcgcata tttttcttcg taaacggcag tcacttggtc
    37861 tttcactgct tgagttgcag cttcacgggc caatttctct tctacttgaa ctgccttttg
    37921 gaggtcactg ttgtaggctg caatgatttc agcttgcaat tcagcatcca cgtgaagcaa
    37981 ttccacttct gctttttctt taccgacagc agcaacgatt tcttcttgga aggtaatcaa
    38041 ttctttgaca gcttcgtgcc ctttaagaag cgcttccaac atgatttctt ctgacaattc
    38101 tttggcacca gactctacca tgttgatagc gtgcttggtt ccagctactg tcaattcaag
    38161 aagagattgc tctgcttgtt cttgacttgg gttgatgatg atttggccat ctacatatcc
    38221 cacttgtacc ccagcaattg gtccgtcaaa tggaatatct gaaatagaca gtgccaaaga
    38281 tgaaccaaac atagcagcca ttggtgcaga tgcattttca tcataagaaa gcactgtatt
    38341 gatgacttgg acttcattac ggaaaccttc cgcaaacata ggacgaatcg gacggtcaat
    38401 caaacgcgct gtcaaggtcg catctgttga aggacgtcct tcacgtttca taaagccacc
    38461 aggaaacttc ccagccgcat acattttttc ttcgtagttg acttggagtg ggaagaaatc
    38521 cccagttgcc attttcttag acataacggc agcagtcaag acagttgact caccgtaacg
    38581 tacgacaaca gagccatttg cttgcttagc aacctgacca gtctctacaa ttaactcacg
    38641 acccacaaaa gtcgtttgaa acacttgttt tgccatttta atcccctttg gattgatgaa
    38701 attatacgcc ttgcctacaa agatcaagat accaaggacg tcaaaagcaa agtaaaaata
    38761 ggaaactgac gaagtcttcg atgaagacaa gacagtttat cttttttaca cagcttttcg
    38821 gccgtgttca attacacaag atattttgga cggttcggct tgccgaacat ttctgtagaa
    38881 aaataggaag gtgacgtcgc actcgacgag tgctaggaag cttatctttt ttcctaagaa
    38941 atgagaccaa aattcaatta ctcaagatgc taagccgtca agcaactcaa aggaagatag
    39001 gaaatcgaac gacggagcga ctgctcctag ggagatttat ctttttccac agagttgtag
    39061 gcaagttcag ttttcaagat acatcattag aaaggtttaa tattaaagta tctaaacctt
    39121 tcacgctaat tgctatcggg cgattagcta aatgctttac taactctttc gtcaaataac
    39181 atcgatttga ctcactcgtg tcgttaaatc ttacagttta aatgcattgt attatttaat
    39241 accttcatct ttgtatcaag tacgtacaga atctatttta tcatattttt cttaaaaagt
    39301 gaggtctttg ccattaaaaa ggaaccattc ccctcacctg agaagaatgg tttgctttta
    39361 ttatcctaga gactggtgat taaacaaggc atgggttgct tgatggatgt attttgctgt
    39421 atcagcatta ttcatcgtat agagatgcac accggcaaca tcctgagtta ccaagtccac
    39481 gatttggtcc actgcatagg caagtcctgc tgctctgagc gactcagggt catgctcata
    39541 cttgtctaag atggctttaa atttgcgtgg aagatggata ttctcacaag tcttcaagag
    39601 tcggagagcc tgatttcgat tcagaattgg cataattcct gcatgaatgg gaacatcaat
    39661 cccagccaag atgcacttgt cctgaaaatc atagaagcgc tcattgtcaa agaagagctg
    39721 agttacgagg ctcgaacagc ctgcatccac tttcttctta agattttgaa tatctgaaat
    39781 ctgatttggc gaatctggat gcccttctgg atagcaagct ccaataatat caaagtgagg
    39841 ggtttgttcc ttgataaact caatcaagtc ggttgcatag cggaaatcct tttgtggttc
    39901 cacgtctgga ataatatccc cacgaagagc caagattttc tgcaccccaa ctttgtccaa
    39961 gtcagcaata gtttcagcaa ccttgtcctt agttagataa atagctggca agtgggcaat
    40021 ggtcggaatc gccaaatcat tttggataaa gtcagccaaa cgaaccgtcg tttccttgat
    40081 attaaattta ttattgctgg cagttacact gataaaatgg ggagccaact cctgcatatc
    40141 ctgcaaggct gaaataatgt taccattacc cacagctggg tttggaggga acacttcaaa
    40201 tgagagtgac ggtgtttggc gtgacatatg taataacctt ttctagttga tttctttttg
    40261 aacaaccact gtatggagag aaatccaatc ttacaatttc tcacgcgcag ctttagctgc
    40321 ttcaacaagg cggatcaagc tttcttttgt ttctgggata ccacgtgttt tcaaaccaca
    40381 gtcagggttg atccaaactt tcttgcttgg cactttagca aggatggctt cgattgtgtt
    40441 gtcgatttcg ccttcatttg gtacacgagg tgagtggata tcgtaaaccc caggtcccac
    40501 ttctgtttgg aagtttttcg ctttgagttc gtccaagatt tcaaggtttg aacggctagc
    40561 ttcaaaggaa ataacgtctg catccatgtt atcgatagct gggatgatat ctgtaaattc
    40621 tgagtaacac atgtgagtgt ggatttgtgt gtctggcgct actgttgagt gtaccaagcg
    40681 gaaggcagga atagcccagt caaggtagtc ttcgtaccag tcgctacggc ggagtggcaa
    40741 tttttcacga agagcagcct cgtcgatttg gatgattttc acaccagcag cttcaaggtc
    40801 aagtacttca tccttgatag caagggcgat ttggagagtt gaatccttga tagagatgtc
    40861 ttcacgtggg aatgaccagt taaggatggt aacaggtcca gtcaacatac ctttaacagg
    40921 tttgtttgta cgactttgtg catagctaga ccatttaaca gtgatagggt taagacgagt
    40981 gacatcaccc cagatgattg gtggttttac cccacgcata ccgtatgatt gtacccatcc
    41041 atttttagag aagaggtatc ctgacaagtt ttgaccgaag tactcaacca tgtcattacg
    41101 ctcaaattca ccgtgaacaa ggacatcaaa gtcaatatct tcttgccact tgatccattc
    41161 gtcaatcgtt tcagcaagga aagcatcgta ctctttttga gacaattcac ctttacggta
    41221 agccaaacgt ttggcacgaa cttcttttgt ttgagggaat gaaccaatcg ttgttgttgg
    41281 aagagctgga agtttgaaag cttcttcttg gatagcttca cgttctgcaa aggctggcaa
    41341 acgagtgtag tctgcgtctg tcaagccagc gatacgcgca cgaagttcag cattttcacc
    41401 aacacgctca gtcgcaaaga gttctttgtt ggctgcaaga gcttctgaac cttgaccatt
    41461 gcggatagca tccaagtcac ggatttcatc caatttttca actgcaaagg caaagtggtt
    41521 caagagtgct ggttcaaatt cttcattagc agttgtaaat ggcacatgaa gaagtgagca
    41581 agagcttgtc aaaacgatgt tttcagctgg aatttgctca agaacagcca agctcttttc
    41641 gtagttgttg cgccagatgt ttttaccatt gacaatacct acatagagag tcttgtcagc
    41701 tgggaagcca cctttaacga gttcaagagt tttcttacct tcaacaaagt caagaccgat
    41761 agcatctact ggtaagttta caaggtcagc gtatacgtca cgaacatcac cgaaataagt
    41821 ttgaagcaag acttcaagac cttttttgtc agccaagagt ttgttgtaaa ggttcaagaa
    41881 gagagctttt tcttcagctg tcaagtcttt tacaagagcc gcttcatcca attggatgca
    41941 agtcgcacca agttcagcca atttagcaaa aacttcttgg taagcagcca ctaagctatc
    42001 tacgaagtcg tctgctttca cgccttcttc aaagtctgac aattgaagga aagtgaaggg
    42061 acctacaaga actggacgag tgttcaatcc aagttctttt gcttcttgga actcatcgaa
    42121 aatcttgtga ccagccaatt tcacttgagt gtctttttca aatttaggaa cgatgtagtg
    42181 gtagttagtg ttgaaccatt tcttcattgg aagggcgcga acgtcccctt tttctccctg
    42241 gtaaccacgt cccaaagcga agtagcgctc aaggtcagac aagtccaagt tttgaacaga
    42301 tgcaggcacc acgttgaaaa ggaaagccgc atctaggaag ttatcatagt gagaaaagtc
    42361 atttgatgga atttcagtga tgcctttttc tttgacaatg ttccagtgtt tagcacgcaa
    42421 gtcttttgct gctgctaaaa gttcttcttc tgagatttct tttctaaagt atttttcagt
    42481 tgtaaatttt aattcacgga attcgcccaa acgagggaaa ccgatgattg tagttgacat
    42541 gatgtgtcct ccaaaatttg ttgttgaaac tatcttaaca gaaaagaaag cgtctgtata
    42601 attgtaaaaa attagggttt gatatagttt gaaactatat atctgtttcg gacaaaagaa
    42661 aaagacttga agcaaacgtc tcaaatcctt tgtatagctt gttttatagc tgtattttag
    42721 ttagaatgct caaacgcgtt attagtaatt cttataagtg actatggctt gttattagaa
    42781 aagactataa ctgattctag tcaacttttt ccctgttcaa gtgggacgat tgctagtgtc
    42841 tttcctaaac tggctaggac ttttaagact gtatccaact gaggactagt ctttcctgtc
    42901 tccatcctag ctatgacagg ctggcttatt ccactgactt cttccagctt tttctgactg
    42961 attccttgtt catacctagc ctcaatcaac tcgctcatga tagccactcg catatcactt
    43021 tcaaggattt cctccttgct aaagagctca gatggacatc cttccaatta ctcccaatag
    43081 cactattctt catcacttaa ccctcttttt tttacgtcta tgtattttta aaaaaatgag
    43141 cgaattatga ttcgatagat tgaccagcgg gtttaaagtt ggtgctagcc tatttcttaa
    43201 gcgattttcc ttttctagga taaagcagat cctgcttgct taaccccaat tttccacgat
    43261 gaatccaata gtaaatggtt gaaattccca cgttaacccc tttagccatc accatcattt
    43321 caggcgaaaa tttttgatta tgtatagtgg agaatctttt cctttagttc cttggtcaag
    43381 cttgatttct tgaccgagcg cttgcgattg ttttcataag actgttgagc gtagtcggca
    43441 gaataaacct ctttgaagcg cccttttcca agacattgtc ggactgtccc acgcttgatt
    43501 tcagtgtgga tagtttgagg agcttttcca agtagagagg caacttctct atttgatttt
    43561 ccttcttttt tccatctttc gattaagcga cggctatcga ttgtcaaatg tttacctttt
    43621 gtagtataat tgtcttgcat ctctgtgcct tttaatcatt tcaatcttaa attggacttt
    43681 ttttacttgg gttgtactta atctataagg aagacaataa aaagaatatc aatcaagtaa
    43741 agtcacaaag tcacattagc tccgagcaac cattgcaaat tgaggtactc acacaatgat
    43801 taaaacattt ctctctgccc tttcggtcat tctctttgtt atccctatca tagcttattc
    43861 tttttttcca tcttctaatc ttaatatttg gctatctacc agacctatct tggcacagat
    43921 ttatgccttc cccttagcta ctgcaactat ggcttctatt ttaagtttcg tatttttttc
    43981 cctatctttt tacaagaaaa ataaacaaat acggttttac tctggcattt tgctcttact
    44041 atcgctcata ttactattat tcggaacaga taaaaccctt tcttctgcat caaataagac
    44101 taaaacctta aaattagtaa cttggaacgt cgctaatcaa atagaagcac aacatattga
    44161 gcgaattttt agccattttg atgccgatat ggctatattc cctgaactag ctaccaatat
    44221 cagaggtgag caagaaaacc agagaatcaa actattgttt catcaagttg gactttctat
    44281 ggccaactat gatattttca cttctccacc taccaatagt ggaatagctc ctgtgactgt
    44341 gattgtcaag aaaagttatg gtttctatac agaagctaaa acttttcata caacacggtt
    44401 tgggacaatt gtattacatt cgagaaaaca aaatatacca gatatcattg ccttgcatac
    44461 tgctcctcct ctgccaggtt taatggaaat ctggaagcaa gacttaaaca tcattcataa
    44521 tcaattggct tcaaaatatc caaaggctat tattgcaggt gattttaatg caactatgcg
    44581 tcatggagca cttgcaaaaa taagctctca tagggacgca ttaaatgtac tgccaccttt
    44641 tgaaagagga acttggaata gccaaagtcc aaaacttttt aatgcaacaa tagatcatat
    44701 tttattgcct aaaaaccact actatgttaa agatttagac attgtaagtt ttcaaaactc
    44761 tgatcataga tgtattttta cagaaatcac attttaatta ttttatataa aatcacccct
    44821 ctagtgttca taaactagag ggggaatttg tatcatacta tcgtttaacg cacttctgca
    44881 ttcacttttt cttcgagcga tgcttggatt ttttccatat agcgtgcgac ttcttcgtcc
    44941 gttaagctat cttctggatt ttggaaggtc aagctataag ccattgactt cataccaagt
    45001 cccaatttct cacctgagaa gacgtcaaag agtttgatat ctgtcaaacg tttcacgccg
    45061 gcagcttgga tagcatctac aacttcttga tgagtcactt ctgccttgag gagaagggca
    45121 acgtcacggc tgactgctgg gaatttcgtg atttccacaa atggaacagc aggttggagc
    45181 gccccttcga tggctgaaag gttaagctca gctacatacg tttctggaat atcgtaagcc
    45241 ttggcagtga ctggatgcac ttggccaagg aaaccaagaa cttggtcacc gagtgaaatc
    45301 acggctgtac gacctggatg aaggctagcg atttcagatg ttgctgtata ggttacttgg
    45361 agtcccaaac gagtaaatag ggcttcaagg attcccttag catagaagaa atcaactgga
    45421 actgctgctg tttggaaatc tttttcagca accaagcctg tcaaggcaaa ggcaaaactg
    45481 ttgatttcat ttggaagttc ttcttttgga ttacctgttt gttcaaagac ttttccaatc
    45541 tcgtaaagag ccaagttttt attcttacga gccacgttgt aggcaacggt atcaaggata
    45601 cctgaaatca tattttgacg gaggactgaa cgatccacag tcattggcca catgagttca
    45661 gtaaggttac ttggttgagc cgtaaactca actgcttttt caggagttgt cagagcatag
    45721 gtgatgattt ctgtcaaacc tgctccttca gcaatagtac gaacttgacg gcggagtttt
    45781 tgtgtggctg tcaattcacc tgctgtacca tcgtcttttg gtagactagt tggcaagcgg
    45841 tcataaccat agatacgagc aatttcttca aaaaggtcag cttcgattgt gatatcccaa
    45901 cgacgacgtg ggactctgac tgtaaagctg tctgcatttc cagaaagacc aaagccaaga
    45961 cgacggaaga cgtcttctac atcagcataa gacagctcag ttccgaggac acggttaaca
    46021 tcagcaaggg ttgaagaaac ttctacatct gaagtatcaa gctcacccgc tgaaacgatg
    46081 cccttacgca ccgtcgcacc tgcaagttcc gcaatcaggc tagatgccgc atcaagggct
    46141 tcattaactg ttgccacatt aattcctttt tcaaagcgag aagatgactc agaacgaagg
    46201 ttcaggcgac cacttgtctt acggatagat ttgccattga aaacagcagc ttcaaggaca
    46261 acacgactag atttttcaga gatttctgtt gcttgaccac ccatgacacc tgcaagggct
    46321 actggcttgt ctgcgacagt gatgactagg tcattcacgt ccaagtcacg ttcttcaccg
    46381 tccaaggtca ccaatttttc accagcacgc gcttcacgca cacggatgtc agtcccttca
    46441 aagttatcca agtcaaaggc atgcattggt tgaccaaaat agagcaggat gtagttggtc
    46501 acgtccacta cgttattgat gggacggatg ccttcgttca tgagaaggtt ttgcaaccat
    46561 tgtggacttg gtgcgatggt cacattttcc aagatacgag ctgcatagta aggcgccttg
    46621 tctgtctcaa tgctgacaga aagggcatct gccgcagctt cattagtttc tgttagagta
    46681 aattctttaa agttgactgc cttgtcatag atggctgcca cttcgtgagc cactccacac
    46741 atagaaaggg catctgcacg gtttggtgtg atggaaagtt cgatgatttc atcatccaag
    46801 tctaggtaag aaaagacttc ctcacctggc acggcatctt caggcaagat ttggatgcca
    46861 tctgcgaatt ccttaggcac aactgagtca gaaatcccca attcaccaag tgaacagatc
    46921 attccaagtg actccaaacc acggattttt ccttttttga ttttgtagtt atcagcgata
    46981 cgagctcctg gaagagccac catgaccttg atcccagcac gcacatttgg ggcaccacaa
    47041 acgatctgac gggcttcttc ttcgccaacg ttaacctgac aaacatggag gtgagtctct
    47101 ggcacatctt cgcaagacaa gacctcaccg acaacaattt ttgagagatc agcagctggt
    47161 gattcgacac tctctacctc gatccctgtg gttgacattt tttcagccaa ctcctgtgat
    47221 ggcacatcaa tgtccaccaa ttcttttaac catttataag atacaagcat aatttagttc
    47281 tccagaatga ccattgccac actggttctt ttcctttcct atcatttcaa tagaagaatc
    47341 ctcttcttac cttaatttct ttctcagtaa ccaatccgta tctacttttt gaccaaccat
    47401 aaaatgatgt tggctaaatt tttcaaaacc atatcgatta taaaacgctt gagcttttgt
    47461 attatgctcc caaacaccta gccaagccca agaaaaacta ttttttgtag caagttcaag
    47521 tgcgaattca aacagttgct tacctattcc aaatccttgg aatttttgta gcacatagag
    47581 gcgttgaatt tcaaaagcgt cctctaattc tctctcagtt tgagcacttc cccagttgac
    47641 tttgagaaaa ccagctatct cctcctcatg cataatgaaa taggtttcag agtcaggatt
    47701 tcccaactca gttgacaaag ttttcagact ataagcctct tcaaagtatt cctgtaactg
    47761 ctcttccgta ttatcatacg caaaggtttc acgaaaggct tgtttggcaa ttttagccaa
    47821 cacctcaaca tctgccattt ctacttttct aatcattatt taaactgttc tgagaagcgg
    47881 acatctcctt ggtagaatcc acggatatcg ttgattccat aacggagcat agctacacgc
    47941 tcttgtccaa gaccaaaggc aaaaccagag tatacagtcg catcgatacc actcatttca
    48001 aggacacgtg ggtgaaccat accggctccc ataatttcga tccaacctgt tttcttacat
    48061 acgttacagc cttctccacc acacttgaag caagaaacat ccacctcaac agatggctct
    48121 gtgaatggga agtaagatgg acgcaaacga atttgacgct cttcaccaaa cattttttgg
    48181 acaatcaact gaagcgttcc ttgaagatca gccatagaga tatttttccc aactaccaag
    48241 ccttcgattt ggtggaattg gtgactgtgg gtcgcatcgt ccgtatcgcg acggaagaca
    48301 cgccctggcg agatcatctt caaaggacct ttagaaaaat catgggcatc catagcacgc
    48361 gcctgaactg gagacgtgtg ggtacggagc aagatttctt cagtgatata gaaagtatcc
    48421 tgcatatcac gagctgggtg gtcttttgga aggttcatac gttcaaagtt atagtagtct
    48481 tgctctactt caaaaccatc cacgacttga taacccatac cgatgaagat atcttcgatt
    48541 tcttcactgg tttgtgtcaa aacgtgacgg tgaccagtcg caactggacg acctggaagc
    48601 gtcacatcga tactctcgct agccagttga gccgcgactt tcttttcttc caagagctta
    48661 gctgtttctt caaaagcagc agtcaagaca tcacgagctt cattgacgtg tttcccgatg
    48721 attggacgca tctcagcaga aacatctttc atccctttga ggatttcagt gagcgaaccc
    48781 tttttaccaa ggacagagac acgcaaatct tgcatctctt tttcatttcc agcagtaatc
    48841 tgcttcaagc tagccagcgt ttcttcgcga agcgctttta attgttcttc aatagttgac
    48901 atatttcctc catcagtctc tcgtagataa aaagaaaacc acatgccaaa aactccactc
    48961 ggagcgttga cacgcggtac catccgtttt catctgacaa gtcagacctt catttctaaa
    49021 tccatgcgca agtgaattca cccagctttc atatagagag cttgcagtca cggctctcct
    49081 ccctgatata cttcccttgg gctactagtc tttcagattc ctattcaatt actacttagt
    49141 ttatcagatt tttaccattc ttgcaagacc tatcttactt ctgcttgtta gcttattctt
    49201 atctaact
//
LOCUS       DBEJZJ010000014        45213 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000014 DBEJZJ010000000
VERSION     DBEJZJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.14"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(287..2938)
                     /gene="adhE"
                     /locus_tag="ACL3R8_000991"
                     /gene_synonym="adhC"
     CDS             complement(287..2938)
                     /gene="adhE"
                     /locus_tag="ACL3R8_000991"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR1313890.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(3239..3649)
                     /locus_tag="ACL3R8_000992"
     CDS             complement(3239..3649)
                     /locus_tag="ACL3R8_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR1313891.1"
                     /translation="MENPTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(3651..4079)
                     /locus_tag="ACL3R8_000993"
     CDS             complement(3651..4079)
                     /locus_tag="ACL3R8_000993"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR1313892.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(4126..4425)
                     /gene="yajC"
                     /locus_tag="ACL3R8_000994"
     CDS             complement(4126..4425)
                     /gene="yajC"
                     /locus_tag="ACL3R8_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR1313893.1"
                     /translation="MNPNYTFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(4542..6518)
                     /gene="tkt"
                     /locus_tag="ACL3R8_000995"
     CDS             complement(4542..6518)
                     /gene="tkt"
                     /locus_tag="ACL3R8_000995"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR1313894.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(6632..7723)
                     /gene="ulaG"
                     /locus_tag="ACL3R8_000996"
     CDS             complement(6632..7723)
                     /gene="ulaG"
                     /locus_tag="ACL3R8_000996"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR1313895.1"
                     /translation="MPNVKEITRELWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RINVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLTVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(7835..9508)
                     /locus_tag="ACL3R8_000997"
     CDS             complement(7835..9508)
                     /locus_tag="ACL3R8_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR1313896.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEQEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(9687..10391)
                     /locus_tag="ACL3R8_000998"
     CDS             complement(9687..10391)
                     /locus_tag="ACL3R8_000998"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR1313897.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(10393..11256)
                     /locus_tag="ACL3R8_000999"
     CDS             complement(10393..11256)
                     /locus_tag="ACL3R8_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR1313898.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(11260..11925)
                     /locus_tag="ACL3R8_001000"
     CDS             complement(11260..11925)
                     /locus_tag="ACL3R8_001000"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR1313899.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            complement(11942..12427)
                     /locus_tag="ACL3R8_001001"
     CDS             complement(11942..12427)
                     /locus_tag="ACL3R8_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1313900.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(12504..12785)
                     /locus_tag="ACL3R8_001002"
     CDS             complement(12504..12785)
                     /locus_tag="ACL3R8_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1313901.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(12808..14265)
                     /locus_tag="ACL3R8_001003"
     CDS             complement(12808..14265)
                     /locus_tag="ACL3R8_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1313902.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(14396..15019)
                     /locus_tag="ACL3R8_001004"
     CDS             complement(14396..15019)
                     /locus_tag="ACL3R8_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR1313903.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMKALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(15070..16056)
                     /gene="jag"
                     /locus_tag="ACL3R8_001005"
     CDS             complement(15070..16056)
                     /gene="jag"
                     /locus_tag="ACL3R8_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR1313904.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(16075..16899)
                     /locus_tag="ACL3R8_001006"
     CDS             complement(16075..16899)
                     /locus_tag="ACL3R8_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR1313905.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(16874..17245)
                     /gene="rnpA"
                     /locus_tag="ACL3R8_001007"
     CDS             complement(16874..17245)
                     /gene="rnpA"
                     /locus_tag="ACL3R8_001007"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR1313906.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(17262..17393)
                     /locus_tag="ACL3R8_001008"
     CDS             complement(17262..17393)
                     /locus_tag="ACL3R8_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313907.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            complement(17394..18584)
                     /locus_tag="ACL3R8_001009"
     CDS             complement(17394..18584)
                     /locus_tag="ACL3R8_001009"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR1313908.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFSCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(18635..19588)
                     /locus_tag="ACL3R8_001010"
     CDS             complement(18635..19588)
                     /locus_tag="ACL3R8_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1313909.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(19649..20243)
                     /locus_tag="ACL3R8_001011"
                     /pseudo
     CDS             complement(19649..20243)
                     /locus_tag="ACL3R8_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(20380..20793)
                     /gene="comGG"
                     /locus_tag="ACL3R8_001012"
     CDS             complement(20380..20793)
                     /gene="comGG"
                     /locus_tag="ACL3R8_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR1313910.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(20771..21232)
                     /gene="comGF"
                     /locus_tag="ACL3R8_001013"
     CDS             complement(20771..21232)
                     /gene="comGF"
                     /locus_tag="ACL3R8_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR1313911.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            complement(21195..21497)
                     /gene="comGE"
                     /locus_tag="ACL3R8_001014"
     CDS             complement(21195..21497)
                     /gene="comGE"
                     /locus_tag="ACL3R8_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR1313912.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(21460..21864)
                     /gene="comGD"
                     /locus_tag="ACL3R8_001015"
     CDS             complement(21460..21864)
                     /gene="comGD"
                     /locus_tag="ACL3R8_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR1313913.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(21857..22183)
                     /gene="comGC"
                     /locus_tag="ACL3R8_001016"
     CDS             complement(21857..22183)
                     /gene="comGC"
                     /locus_tag="ACL3R8_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR1313914.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            complement(22185..23201)
                     /gene="comGB"
                     /locus_tag="ACL3R8_001017"
     CDS             complement(22185..23201)
                     /gene="comGB"
                     /locus_tag="ACL3R8_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR1313915.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(23149..24090)
                     /gene="comGA"
                     /locus_tag="ACL3R8_001018"
     CDS             complement(23149..24090)
                     /gene="comGA"
                     /locus_tag="ACL3R8_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR1313916.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(24166..24531)
                     /locus_tag="ACL3R8_001019"
     CDS             complement(24166..24531)
                     /locus_tag="ACL3R8_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR1313917.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(24682..25740)
                     /locus_tag="ACL3R8_001020"
     CDS             complement(24682..25740)
                     /locus_tag="ACL3R8_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR1313918.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(25903..27054)
                     /gene="nagA"
                     /locus_tag="ACL3R8_001021"
     CDS             complement(25903..27054)
                     /gene="nagA"
                     /locus_tag="ACL3R8_001021"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR1313919.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(27207..29024)
                     /locus_tag="ACL3R8_001022"
     CDS             complement(27207..29024)
                     /locus_tag="ACL3R8_001022"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR1313920.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHIILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(29125..30267)
                     /gene="tgt"
                     /locus_tag="ACL3R8_001023"
     CDS             complement(29125..30267)
                     /gene="tgt"
                     /locus_tag="ACL3R8_001023"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR1313921.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            30397..31254
                     /locus_tag="ACL3R8_001024"
     CDS             30397..31254
                     /locus_tag="ACL3R8_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR1313922.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFILDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(31282..31926)
                     /gene="pcp"
                     /locus_tag="ACL3R8_001025"
     CDS             complement(31282..31926)
                     /gene="pcp"
                     /locus_tag="ACL3R8_001025"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR1313923.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(32001..32402)
                     /locus_tag="ACL3R8_001026"
     CDS             complement(32001..32402)
                     /locus_tag="ACL3R8_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR1313924.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            complement(32413..32838)
                     /locus_tag="ACL3R8_001027"
     CDS             complement(32413..32838)
                     /locus_tag="ACL3R8_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR1313925.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(33161..34273)
                     /locus_tag="ACL3R8_001028"
     CDS             complement(33161..34273)
                     /locus_tag="ACL3R8_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR1313926.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(34439..35059)
                     /locus_tag="ACL3R8_001029"
     CDS             complement(34439..35059)
                     /locus_tag="ACL3R8_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1313927.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(35063..36343)
                     /locus_tag="ACL3R8_001030"
     CDS             complement(35063..36343)
                     /locus_tag="ACL3R8_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR1313928.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(36404..37888)
                     /gene="thrC"
                     /locus_tag="ACL3R8_001031"
     CDS             complement(36404..37888)
                     /gene="thrC"
                     /locus_tag="ACL3R8_001031"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR1313929.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(37964..39241)
                     /locus_tag="ACL3R8_001032"
     CDS             complement(37964..39241)
                     /locus_tag="ACL3R8_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR1313930.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(39504..39752)
                     /locus_tag="ACL3R8_001033"
     CDS             complement(39504..39752)
                     /locus_tag="ACL3R8_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313931.1"
                     /translation="MLYWISVNYEITEDEDFETVKTRVISDFESYLKLLNGKFEESLK
                     KVIKSFTFSKLIGEKLCNGEDLKNLSKEIRHQIQDRNS"
     gene            39912..40388
                     /locus_tag="ACL3R8_001034"
     CDS             39912..40388
                     /locus_tag="ACL3R8_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313932.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            40559..41113
                     /locus_tag="ACL3R8_001035"
     CDS             40559..41113
                     /locus_tag="ACL3R8_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313933.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            41389..41775
                     /locus_tag="ACL3R8_001036"
                     /pseudo
     CDS             41389..41775
                     /locus_tag="ACL3R8_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
     gene            41769..41891
                     /locus_tag="ACL3R8_001037"
                     /pseudo
     CDS             41769..41891
                     /locus_tag="ACL3R8_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            41895..43028
                     /locus_tag="ACL3R8_001038"
     CDS             41895..43028
                     /locus_tag="ACL3R8_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1313934.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            43069..43506
                     /locus_tag="ACL3R8_001039"
     CDS             43069..43506
                     /locus_tag="ACL3R8_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR1313935.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
     gene            43714..43950
                     /gene="relB"
                     /locus_tag="ACL3R8_001040"
     CDS             43714..43950
                     /gene="relB"
                     /locus_tag="ACL3R8_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR1313936.1"
                     /translation="MNNVVTTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            43943..44674
                     /locus_tag="ACL3R8_001041"
     CDS             43943..44674
                     /locus_tag="ACL3R8_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR1313937.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(44785..44868)
                     /locus_tag="ACL3R8_001042"
     tRNA            complement(44785..44868)
                     /locus_tag="ACL3R8_001042"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44832..44834),aa:Leu,seq:caa)
     gene            complement(44878..44949)
                     /locus_tag="ACL3R8_001043"
     tRNA            complement(44878..44949)
                     /locus_tag="ACL3R8_001043"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44915..44917),aa:Gln,seq:ttg)
     gene            complement(44963..45035)
                     /locus_tag="ACL3R8_001044"
     tRNA            complement(44963..45035)
                     /locus_tag="ACL3R8_001044"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45000..45002),aa:His,seq:gtg)
     gene            complement(45050..45120)
                     /locus_tag="ACL3R8_001045"
     tRNA            complement(45050..45120)
                     /locus_tag="ACL3R8_001045"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45086..45088),aa:Trp,seq:cca)
     gene            complement(45125..45205)
                     /locus_tag="ACL3R8_001046"
     tRNA            complement(45125..45205)
                     /locus_tag="ACL3R8_001046"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45169..45171),aa:Tyr,seq:gta)
BASE COUNT        13733 a         9698 c         8007 g        13775 t
ORIGIN      
        1 atatttttta tatattaaaa tgaaataaga acaggacaaa ttgatcagga caggcaaatc
       61 gaattctaac aatgttttag aagcagatgt gtactactct agtttcaatc tattatatat
      121 tttgtttcta ttctagtttt tcaaaaaggg caaaaaggcc tcaatatcat aaaaaggcat
      181 cctatcaggt gttcaaaaac cttgatagga tgccttttat catagaaaaa ttactggatc
      241 tttccctcaa attgagtttt tgtcttgctt ctagactgat aaacaattat ttacggcgtc
      301 ctggtctttc tttgtagcca tagtatgcat cttcgatgat ttcttgcata tggtctacca
      361 ttggaagacg tgggttagct ggtgaacatt ggtcttcata agccaggaag gctaattcac
      421 gagaatgttc tttccattct ttttcgtcaa ttccttggtc tctaaaattc atttggatcc
      481 caatacgttc accgagttcg tagacagctt ttgcgtaaga ttcaacccct tcttctggag
      541 tagaagctgg aagtccaagc atgcgtgcga tatcttggta tttttcatct gcacggtagt
      601 agttgtactt aggccatgtt gctgtcttag ctggacgtgt accgttgtaa cggataacgt
      661 atggaagcaa gatagcattt gtacgaccgt ggattgtgtg gaattgcgca ccaatcttat
      721 gggccattga gtgagaaata cctaggaagg cattggcaaa ggccatacca gcgattgttg
      781 aagcgttatg cattttctca cgtgagtgga agtctgcatt cttaactgag ctttcgagat
      841 tttcaaagac caatttaatg gcttgaagtg ctaaaccatc agtgtagtca ctagccattt
      901 gtgatacgta tgcttctgtc gcgtgagtca atacgtccat accagtatca gcagcaacaa
      961 atcctggaac tgtcaatacc aaagcaggat ctacgattgc cacagttggt gtcaatgagt
     1021 agtcagcgat tgggtattta cggttgtttg ctttatcaga gataacggca aatggtgtta
     1081 cttcagatcc tgtaccagat gtagttggaa tcgcgatgaa tttagtcttc ttaccaagca
     1141 atgggaactt gaaggcacgt ttacggatat ccatgaattt ttggacaagg tcacggaagt
     1201 ccacttctgg ttgctcgtag aagagccaca ttactttggc agcatccatt ggagacccac
     1261 caccgagtgc gatgatggta tctggtttga aggcacgcat aatctcagta ccacggttta
     1321 cagttgtgat atctggatcc ggttctacat ccgcaaagat ttggtaaaca accttattgc
     1381 gacgaaggtc cagttgttcg atgatacgat caaggaaacc aagctctacc atggcatggt
     1441 cagtaacgat catgacacgt tcaacgtcac gacatttttg aaggtattga attgaatcac
     1501 gttcaaagta tgtttttgaa ggaagtttca tccattgcat gttatttctc cgtcttccga
     1561 cttttttgat attcaagagg ttaatggcac taacgttatc cccaactgag ttgcgtccgt
     1621 aagaaccaca tccaagtgtc aatgatggca agaaggcatt gtaaacgtcc ccgataccac
     1681 caaaagtaga aggtgagtta cagataacac gaatagcttt aacagcttta ccaaattctt
     1741 tagtcaattc ttcgtcagct gtgtggatag ctgctgagtg tccaagaccg ttaaattcaa
     1801 ccatttgacg agccttagta ataccatctt cacggctttc agatttcaaa actgcaataa
     1861 ctggtgacaa tttttcacga gtcaatggct cattttcgcc aacttcttta cattctgcag
     1921 caagaatgtt tgttccttct ggaactgtaa atcctgcttg ttctgcaatc caagttgctg
     1981 gtttaccaac gatgtcagcg ttcaattttg caccagcaca gtttttgctg tttgctttga
     2041 caccgaagca gaactcttca agaagagctt tttctttttt gtttacaaag taagtgtggt
     2101 aagatttgaa ctctgctaca aattcatcgt aaatttcttt atcaatgata actgcttgtt
     2161 cagatgcaca gaccataccg ttatcaaatg atttagacat gacgatatcg tgtgctgctt
     2221 gacgaatgtt tgctgatttt tcaacataag ctggaacgtt tccggcacct accccaagag
     2281 ctggtttacc acatgaataa gccgccttaa ccatggcatt accacctgtt gcaaggattg
     2341 tcgcaacacc ttcgtggttc ataagggcac ttgttgcttc catagatggt tgagtaatcc
     2401 attgtacaca gttttcagga gcaccagctg cgatagctgc atcgcggacg atacgagctg
     2461 catgagctga tgattcttga gctgatggat ggaaggcaaa gacgattgga ttacgtgtct
     2521 tcaatgaaat caatgatttg aagatcgctg ttgatgttgg gtttgttgtt ggagtaatac
     2581 cacaaacaac accaactggt tcagcaataa gagtcaatcc tgttacatcg tcttcttcga
     2641 taacgccaac tgtcttagtg tggcgcatgt tgtttactac gtgttcacag gcaaacaagt
     2701 tcttagttgc tttatcttca aatacaccac gtcctgtttc ttcaaaggca tgtaaagcca
     2761 attctccgtg ggcatccaaa gctgctactg atgctttggc aacgatgtag tcaacttgct
     2821 cttgatccaa tttacgcatt tcttcaaggg caactagagc tttttgaacc aactcatcta
     2881 cgtgtttttc agcaacgagt ttcttttcct ctggtgtcac agttttttta tcagccatat
     2941 tttcctccat agctttcaag gaacgatatc ctttgttaat tttttcacaa gtttattata
     3001 acgcattatt tcaactttgt aaacagtttc ataaacattt cacaaagaat ttttaaactc
     3061 ttgtgaaact tttctcattt tcttttctta tcaggtttta tctttaaagt ttgtgaaatt
     3121 tatttcaaat attttttatt tcacaaactt gcttggaaga gggatttgga aagaaaggga
     3181 tttacaggta agcgcttacc ttgtggttct aataatacct cctttggata aggaggcttt
     3241 atttttgttg aaaaacgcct tgtttaaaag ttccttcata aacgacttct tgttctgttg
     3301 ttagtttccc ttttccttca gcctgaccat ttacaaaatc accttcgtag gtccagcctt
     3361 ctttagattg aaaggtacct tttccgttga aggctccatt gttgaagcca cctgtatatt
     3421 ggtctccatt ttggaaggta atggtacctt gaccattcat tttaccacgg acaagactgc
     3481 catcataaac aatcgttcca ttatcgagtt ttaagacacc ttttcctgga atatttagaa
     3541 aaaagacgag tacagcacag aaaacaatgg taactactgc caaaagctct aaacgtggac
     3601 gagtcagata gacacgatac ttttcgtaaa aattcgtagg attttccacc ttaactctcc
     3661 ttttctaaac gttctaacca agcttgacaa ccctcttgaa cacgtcgata ggtttcttca
     3721 aaatctcctg tataccaagg gtctggaaca ctttcagatg aaaatgagta aatcttatct
     3781 tgacagtcta ctggacacat ctgacgtaag tcagaaatat ttgaagcgtc cattccgata
     3841 atataatcaa aggcttcaaa atcttcctta ctaatctgaa gcgatgtctt gttcttgtca
     3901 taaggaatct catactcttg aaaaattccc tgagtcccct tatgaatcgg attgccatgt
     3961 tcccaagagg aagttgctcg actttggatt tcgtagttat ctgtcattga tttcataaca
     4021 aactcggcca tagggctacg gcaaatattt cccagacaga caaagactaa ttttttcatc
     4081 ccatttcctt tcttttatag aaaaacggga gttcgtgatc ccgtcttatt tttcaattgc
     4141 gccttctagt gaagctgttt ctttcagcgg taatactgtc ttgatagcag ctagttcaaa
     4201 agtcaagtaa actccatcta cgtcaagaac tattgttccc ttctccgtat ctacttcatc
     4261 gactgttcca taaagtccac cgattgtaat cacttcatag cctttttgta gtttatttaa
     4321 gctttccata cgcttttgag cttgtttctt ttgagaacgt tgcataaaga acatcaaggc
     4381 catcatacct acaagcatga ttaaaaatgt ataatttgga ttcattgtct tctcctttgt
     4441 cttttacata ggactactat atcaaatttc agctactttt acaagattgt accttacttt
     4501 tctggtaaga aaaaccagag cttacgctct gatttttagg attatttcaa gtttcgaaca
     4561 acttttacaa gattttctac agtaaagcca tattctgcca atacttttgg tgctggggca
     4621 gaggctccga aggtatcaat acctagaacg gcaccatcga gaccaacata tttgtaccag
     4681 ttttgacttg cacccatttc aattgcaaca cgacggcgga ctgcatttgg aagaatttct
     4741 tccttgtaag ctgcatcttg tttatcaaag acatctgtag atggcatgct gactacgcgg
     4801 attttttcgc cttgactagc caattcttta gcagctgaga cagcaagatt aacctctgaa
     4861 cctgtcgcaa tcaagatggt atcaaagtcg gctgcatttt catatacaac ataagcacct
     4921 ttagcaacct tatcgaagtc tgttccatct tcaacagtca agttttgacg tgtcaagaca
     4981 agggcagttg gtgttttctc acttgtcact gcaaggtacc aagctgcttg cgtttcacgc
     5041 gcatctgctg gacggaaaac atttagattt ggcatagcac gaagacctgc taaatgctca
     5101 actggttcgt gagtcggacc atcttcccca actgcgattg aatcatgggt aaagacataa
     5161 gtcacaggaa gtccttgtaa ggctgacaag cggacagctg ccttcacata gtcagagaag
     5221 acgaagaaag ttccaccgta tacacgaagt ccaccatgaa gggccatccc gttcaagatt
     5281 gttcccattg caaattcacg aacaccaaac tgaatgttac gattcaagcg attggcatcg
     5341 tcttgaagtc catctgtctt gatataagtc atgtttgagt gagcaaggtc agctgatcca
     5401 cctaggaagg ttggtaattt agctgccaca acattcaagg catcttgact tgaattacga
     5461 gttgcttgag aaaaaccatt ttctaaagct gggaagtctg ctggagtcac ttcgactgga
     5521 tcacgtccgt cgatgatggc ttctacttct gcagccagtt ctggatgagc ttctttataa
     5581 tctgcaacta atttagtcca agcttgataa gctgatgcgc cacggtctgc aacatgttct
     5641 ttgaaatcag catatacttg ttctggaatt tcaaatggtt cgtagtccca accgagggct
     5701 tggcgagttg atgcagtttc atctgctcca agaggggcgc cgtgtacagc attagttcct
     5761 tgtttgtttg gagaaccata tccaataacc gtcttcactt caatcaaaga tggcttgcct
     5821 gaagcttttg ctgtttcgat agcagcatgg atggcttcca agtctgttcc attttcaacc
     5881 aaggcagtat gccaaccgta ggcattgtaa cggtcacgaa cactttctgt aaaggaatcc
     5941 tttgtctcac catccaagtt gatgtcattt gaatcataaa gaacaaccaa cttatcaagt
     6001 ttttgcaagc ctgcatatga agctgcctcg cttgagacac cttccatcaa gtctccgtct
     6061 ccacagataa cgtaagtata gtggtcaaag atattgtagc cttcacggtt atatttggct
     6121 gccaagaaac gttctgcttg agcaaaacca gtagcagttg aaatcccttg ccctagagga
     6181 cctgtcgtag catcaatccc tgccgtatga ccaaattctg ggtgacctgg tgtttttgaa
     6241 ccccattgac ggaagctctt aatctcatcc atgctgacat cttcaaaacc agaaaggtga
     6301 agaagagcat aaaggagcat tgaaccatga cctgctgaaa gaataaagcg gtcgcggtta
     6361 atccagtttg gttgagctgg attgatatga agttgttttg taaagaggct gtaagccatc
     6421 ggagccgctc ccataaccac acctggatga cctgagttgg ctttattaat ggcgtcaata
     6481 cctagaaaac gaattgcatt aacagataga tttgacatag aatttccttt ctatttgagg
     6541 tgattattga atcacacatt ctattttact attatatgaa aattatccgt atcatgcaac
     6601 atacggataa cctccaaaga atatttttat attatagcaa agctttaaat tgaatgttag
     6661 agtcttgttc aaaacaatca tcaaaaccac gtggatgatg gtattctact aagtgttgat
     6721 cttgaggata agtgtactta ccgccaactt cccagataaa tggatggaaa tcgtattgca
     6781 agcgatcttt tcgcattttc caaagttcta gaatctcatt agtagaagcc atgaagttag
     6841 accagatatc atagtgaact gggataatga ctttggtacg cagattttct gccatacgaa
     6901 gaaggtcgat agatgtcatt ttgtcttgga tacctaccgg attttcacca tagttattca
     6961 aagcaacatc aattttaaag tctttaccat gttttgcaaa atagtttgag aagtgagaat
     7021 ctgcaccatg atagatggtt ccacctggtg tttcaaagat atagttaaca gccttttgag
     7081 ccatttcttc atctgtaaca gtcaagccag caagttcacc gcctgtctca tcagcaccgt
     7141 tcactgggag agttaccaag caagtacggt caaatgattc tactgcatga atcttcatat
     7201 cttttaattc gatagtgtca cctggtttaa caacgttgat acgttctttt ggaacacccc
     7261 atccttccca gattcgtcca cagtggtaag gaccgataaa cttaacatgc tctaacttag
     7321 gattgttgag aattgctgca gctgtgtatg ggtcgatatg atcactgtgg aagtgtgaaa
     7381 ctaagtaata gtctagttcg ttgatagcaa atggatcgat aaccattggc tgaacacgca
     7441 agtttggttg caacttacga acacctgcca tatttgccat ttggtgccca cgaaccatat
     7501 ctttcacttt tttggttgat tttccacggt ttgaccaaag gtccatgaca acgttagcac
     7561 cagctggtgt cttaatccaa gtaccacagt tgcctagcca ccacatggca aagttgcctt
     7621 caggtacgac ttcttcttcg atttcttcgt tcaaccatgt tccccactct gggaaagtgg
     7681 ctaaaatcca taactctctt gtaatttctt tgacgtttgg catatgttgc ctcctttgga
     7741 tataattgtt atctttgaga ttagtatacc acccttcaaa acactaaaaa agaccaagaa
     7801 aaacacaggt ttgtgttcat cattggactg tccttcaaat atcttccaaa aaagcttgaa
     7861 ctactatttc ttgatttata agtgtttgaa cctcttcttg gaacttacta gccaacttgc
     7921 tgtctacaat ataagacgaa ataagactag aaagattttc actgaaactt ttgctctcat
     7981 tacgaaatat attgtgttta agatagtcta gcattttcaa aatatcttct gcttcaagga
     8041 taggattaac ccttaaaatc ggaaatctgc tatccaaatc atcattagta gtaatcacta
     8101 catcaacttg tgcaatatct tccacactct taaattgttc tgttgtaaat acagtgtcaa
     8161 tttgctcatt tggaaaataa agtttgcatt gtttcagcaa aagtctcgaa accgcaacac
     8221 cttcatcaca aacgagataa acttttttca tatttttttg agacgatggt gtatacttta
     8281 aaaatcctcc aatatgaatc gtcaaatagg caatatcatc gtctgttagc cgaataaacc
     8341 atgctccttc taaaatttcc gcagattttc tagtgactaa aaataattct ccatacttgg
     8401 atcgaatttg ttttgttaga ggatttttag aaaaaatacc gtaagtcttt ctaaataaca
     8461 aggctttaca gtggatcatc aaatttcgta acaaatcatc cttgttctca atctccattc
     8521 ggatttgtga ttcaaaatac cagataaatt cttctaaagc aagttttaat tgccgaaaat
     8581 catcactttc tgcatgaata tccaaatctt tacgatagga gaggaggaga acagctacaa
     8641 gagaaacttc aagtcctgac aaagaaattt caaacttttg aaacaaccgt tctcctaatt
     8701 tcttagacac ctgatactct attctttttc ttatcaaaga aaattcttgc tctatatcct
     8761 gatgtctttc ttgatactgt tcaacattat gacagcttaa cagcaaataa ggtagaacct
     8821 gcaacataaa agttatttca tgatggttta ttttcttccc taaatcttgt tcaactaaag
     8881 gaacctgttc cttaaaaaat tggttcattt caacagaaag caaacactca tcatctaacc
     8941 tctctttcat cttatcttct aaaatagata caaaagtggc attttcttcc ataaaaatat
     9001 gatatagaag cgattgaaga tactgaattt tattaagagg gtgggcatga aggtggtatc
     9061 cctgtgactt gctcacttgc aagatcacct gatattgttc caaagttagt tgataacgaa
     9121 tactattcaa atcattgaga acagtattcc tagatacctc tgttaactct atcaattttt
     9181 caatcgtaat acgttcttta gaaataccta tccatagtaa cattatcatc atacgttcat
     9241 gcgcactcat gatataatcg tacgaatcta cttccgataa tagtttacaa caagcatctc
     9301 tctgctcttc cgttaagtga ataccaattc gtggaatact aatgatgtga agcgcctcgt
     9361 caaccagagc agcattgatt ttgtcaatgt gataataaat tttccttctt gactctttca
     9421 aatctttcga aatcgccata atcgttttgg acgtttcttg atccatcaaa tattgaagca
     9481 aatcacaact tgccttatcc agtaccatat taaaaaatcc cccaaatcta ttgatatcac
     9541 agcaattctt tttattttac catatatata tcaagcgcta tttctaaaaa atctttcaaa
     9601 attacttcaa ctccaacttt actctcaata aaaatcaaat gtaaaaagag gagctaaatt
     9661 tatctttttc tcctccttca tcgttcttac ttttgaccat aataagcatt tggtccatgt
     9721 ttacgttggt agtgtttttc tagtatgtac tggggagcag gtccaactct tggattgatt
     9781 tgttctgtaa agcgattcat ctttgatact tcctctagta cgacagagtg ataaacagca
     9841 ttctctggat ttttgcccca ggtgaatgga ccgtgattgc gtacaacaat tcctggtact
     9901 tcaaccgggt taagtccgcg atgttcaaac tcttctacga taaccaggcc agtatctttt
     9961 tcataggcca cttctacttc gtccttggtc aaactacggg cgcaagggat tgaaccgtag
    10021 aaataatctg catgggttgt tccgtagaaa ggaatatcac gacctgcctg agcccaacca
    10081 acagcttctg tcgaatgggt gtgaaccaca ctaccaattt ctgaccaagt cttatataat
    10141 tgcacatgag ttgggaggtc ggaagatggt cttaaatccc cttctaggat cttaccatct
    10201 agatcagtca ctaccatgtt ttcaggtgtc aattcgtcat aatccacgcc tgatggtttg
    10261 ataacaatga caccgagttc gcgattgact tcagatacat tcccccaggt aaatttgaca
    10321 agtccatgtt ttggcaatga ttgattggca tcacagactc gtttacgcat agcattgatt
    10381 acttgattca tcttacatca aacctgcttt cttaatgagt ggatagagaa aagcttgcgc
    10441 ctcttgaatg gctgcgcgtg tttcttctac tgtttcacaa ttttcagacc acatttcgat
    10501 taggaaaggt ccattataat tggtttcctt taaaatatcg aaagcttctt cccatttgac
    10561 acaaccttgc ccgaaaggta catctcggaa ctggcccttt gaactttctg tcactgcata
    10621 agtatccttg agatggagag ctgcgatggc atgatgacca agataaaact cactatagat
    10681 atcattatgc catgcagaca cattaccaat atctggatat acaaagagga agggagagtc
    10741 aatctctttt tctatagcca aatatttttc gatgctactg atgaaaggat catccataat
    10801 ttcaatagca agtaccacct gagcttcttc agcccagtca caggcttttc tcaaattttt
    10861 gataaaacgt tggcgtgtct ggggtgactt ttcctcatag taaacatcgt aaccagctaa
    10921 ttgaatcgta cgaactccca agtcttgagc taattcgata cattttttca tgagttctag
    10981 agatttttcc tctagaactg gatcttttga tcccaatggg tagcgacgat ggcctgaaaa
    11041 acagatagaa ggaatacgaa caccagtttc atagatttct ttgacaactt ccaagcgttc
    11101 ttccttactc cagtcaagtc ttgctaaacg ctcgtcacgt tcgtcaatag acatctcgac
    11161 aaaatcaaag cctaactcct tggcaaaatt taaacgttct agccaagtaa agtgtgttgg
    11221 ggttgccttt tcataaattc caattggacg taccatgatt tacccccaaa ttcgtttgat
    11281 ttcatccttg aaggcacgcg ctgctcctgc tggatccgca gcctctgtaa ttccacgacc
    11341 tgcgataaag gtaaagacat caacaccttc aaagagtttg agagtatcta catctagacc
    11401 acctgttaca gatacacgga agcccatgtc aatgagtttt ttaaccttat taaggtcttt
    11461 ttcaccccaa gtttcaccag caagaagagc atcacgagat tggtgataaa tagcttgtga
    11521 gatacctgca tctagccaaa gctgagcttg ttcaaaagtc caatcgccat aaagctcgat
    11581 ctggatttcg cctcgttctc ctcgttcagt cttgatagcc tttagagctg cttccatagt
    11641 agggatggtt gcacaacaga tacaagtcat ccagtctgct ccacgaaccg cattattttt
    11701 agcaactgtt ccaccagcat cagcacattt tgtgtctgcc acaataatct tatctgggaa
    11761 aaggctacgc aagacttcag ccagttcact tccaacttga agcaagcaaa cagttccagc
    11821 ttcgataata tctacttcct gaccaacaga aacagctgct ttaatcgctc cttgcaagtc
    11881 tgaatggtct aatgcaactt gtaaattagg tattcttttt gtcatttctt tattcctctt
    11941 tctaactttc caaatccaat ccttcgagat aagggctatc cttagattct tcaatcatag
    12001 ccaagacatc ttctttagtc tggcaagcct gtaaacgtgc aatagaatct tctaattcaa
    12061 acagggcaat aatttgtgga atggctacac ttgtgtgaat ttttgaactt gttgctgcta
    12121 gtgccaacaa aacagatacc tctttcccat ctgaaaatac aacaggattt tgtaaggtaa
    12181 tcaatgaaaa ggcatcactt tgcacaccag cttcaggtct agcgtggggc atagccatac
    12241 ctggcatcaa gatatagtaa ggcccatact cttcagtcga ttcaatgata gcatcgtaat
    12301 actctggcaa aattgcccca ctttcaatca agggatctac tgctaccttg actgcttctt
    12361 tccaatcgtt agcctctaaa cctagtcgga tcgagtcgtt gtcaattaaa gcttgtttta
    12421 aattcatatc tgcctccttt atttaaagag ggagaaggac agaaacgata actctcagtt
    12481 tctgtccagc cccctccaac cttttactgt agtgcttgac tgagtttttc ggtgatttct
    12541 ttatcatcca tcaagttatc aagcccaatt aacttcccat tagttcgccc ttccaattct
    12601 tgaatcaaat gaagagaagc gattacgatg tcatatccta ctgctaaacc tttagcttca
    12661 ccgacactgc atgaattgac tgtaaaatct gtttgattaa gcttacggag agcattttca
    12721 accttcatct tgataaccat tgatgaaccc attccatttc cgcacgctgc taatacttta
    12781 accattttat ttctcctttt ctagatacta agcttcttct tgaacttcac cgttgtaata
    12841 tttctcttta tcttttgctt tggcaaattg aagttgagga ataacaagca agaagagaca
    12901 cacaagtaca taaccaacaa taccaaggta tttgaagata tatccaaatc caagccatgg
    12961 gaattcaaag tcgatatttc catggtagcc accataagat gccaaatcga gaagggccac
    13021 acaaagagct cctagagcaa cttgaaggac acctgatata aaggaaagga taacagccgc
    13081 tttccatccg ccgcgtttat cagcgtagac cgcaatggct gcattgtcaa agaacactgg
    13141 tacaaatcct gtaataataa gaatcggatt tttaaagacg atgagcaaaa caattgtaat
    13201 caattgacca atcaaaccaa agataaatcc tgacaggaca gcatttggag aaccaaatcc
    13261 ataagaagct gcaacgtcaa ccgctgggaa tgaacctggc aacaatttgt ttgaaatacc
    13321 ttggaaggcg tttgtcaact cagatacgaa cattcggaca ccttgcatca aaacgaacaa
    13381 gtaaactgag aaggtaaagg ctgtttggat aatgtacata aagaaatctt gtttagcagg
    13441 attgaataga gttcctgaag tgatgacttc tttattagac ataatgtctg gacccaagat
    13501 taaaagaatg gctccgaaga atacgagcat caaggtagca gatgcaacaa ctgtatcgtg
    13561 gaagattgag aggaacttag gtaatttaag attgtctaaa ctttcttctt tcttaccaaa
    13621 gcgtcctgct actttatcta caaaccagat tgcaaattgc tgttggtgac caatcgcaaa
    13681 tccgccacca ccagtcaagc gttgagttgc ctcaacagtc atatttgaac taactgccca
    13741 gtaaagtcca cagatgatac caatcgctgc tgtaccgtaa gcattgcgca attgtggtac
    13801 taagaataga accataagag atactgttgc agcttgttgt accatgatgt gaccagtaat
    13861 aaagagggtt cttaccttcg taatctttcg aagagctacg agcaagatat ttattccaaa
    13921 accaatcaat agagctgtag ttgcagttcc aacaaaatct ggaaactctg ctgcaatttt
    13981 gttgtttgct gcagcaagtc caaagtaagg gtcgataacc gctgcaccaa tttggaattt
    14041 gtagttaaga gctgctaaga ttggacgaaa ggttgtaacc aaaccaccag cacccacgtt
    14101 aagcaacata taccctactg ttgctttaac aaaccctgaa aaaacgtcat gggcaggttt
    14161 tttcaaaagt gcatatccta tcaacaccaa taaacctacg aaaaatgcgg gattctgcaa
    14221 aatattgcta gaaaaccaat ttagaacact tgaaacgact tccataattg ttctcctttt
    14281 gaattgtttt tgtaagttta ttatataatg cgaaagcgca aacaaaaaga ccaagaatta
    14341 cacagcggac tgttcactct tggactgtat gatttatgat gttttacaaa ttatcttatt
    14401 ttctcgtagc tagataatag ggaagaattt tagaataaga cttcaataag ccttctacga
    14461 tttcttcttc agacgaattt tctgtcatag gaacatctac cttcactaaa acttttcgaa
    14521 cttcttgact tctcaccttc tcgcgtaaag tacgacgctt ttcttcattc gcctcccacc
    14581 gttgactttg accattagag taggttagat aataaatccc tttaacggtt ggaatgtcta
    14641 aaactttggt ctgcttgccc agtgtttgct catccttctt acgttcgatg aaactgactt
    14701 ccaaagaaat tccaaagtca gtagatgtcc catacaaacg taaggccttc ataggttctg
    14761 tcacttgtcc gtctctctgt agataaaccc aaaaatgtgg tctcaaacgc tgggcctgat
    14821 tcatccactg actagtctgt tggagttgcc attctggatg gcttgcttga aaggctttgg
    14881 ccagttctgt aaaagccttt cgggcctctt gtcctttgtg gcggaacgcc agcatcttct
    14941 ctcgctctgc tcccgcttta tcaggactac ggtactgcaa accagaaaag tctagatagt
    15001 ctcttatctt attcaacatc agtttaacct cctctagcta gcaaaaaatc aggtcaaccc
    15061 tgattttact tattctgtat ctacaacgac atagcgattt ggctcatcac cttcagagta
    15121 actggtcacg ccatccatac gtgaaataat acggtggata atcttgcgtt cactattcga
    15181 cattggatct gtttgatgac tgcgcccttc ttctaaaaca cgaatcgcca atttttgcgc
    15241 ataggtctgc aagacttctg cacggtgttc aacataatca ttgacattaa tagtgatata
    15301 gaaggttctt gaatagcagt tgtaaagata attttgagcc aacagttgca aggccttcaa
    15361 gactttacca tggtagccga taatacgacc tggttcgtta gtatcaattt gcaaattgat
    15421 gctacgacgg ttataatcat ttgaaagtgt agcctcaaca tccatgtcat caataatcgt
    15481 ttgaacataa gcagtcacat ccgtagccac ctgggcaata tcataacttt gctcgacctt
    15541 caagcccatc tctttcaagt cttgattttc agtttgatct tgctcagttt caaggtcatc
    15601 agcgcctgct tcttccctca tcgcttcctc gatttgaagt tcatttaaaa tctcaatgtg
    15661 accagtttct tctaagatag tgctggcatg tctttcatgt tttaagattt cagccttgac
    15721 ttcatcagaa ataccttgac cttcttcctc tattttttta atagcatcaa ccacatgacc
    15781 aaggtcaacg gtttcttcac taaccgtctt cacaggctcg ttcaaatcat tgattttttt
    15841 cggaacgcct tttactacct gttgatttgc tttgacaaca gtcgtttcac taatcgcttc
    15901 aatatccact tgggctggtt ttttaccaaa tagaccaaga aagccttttt tctccctaga
    15961 aatgactttg atatgagcct tcattcttgg aatatctaat tctttcaatc ctttctggat
    16021 tgcttcttca acagttgaac ctgtaaatac taccattacc agattcctcc ttatttattt
    16081 cgttttctga gcctttttct tggcttttct ttttctattt tccaaatctt tttgtgcctg
    16141 tactacggcc tcgcgctctg cgataatctt gaatggatta ttcaagaaat aggtttgcaa
    16201 gacttgataa gcattagaca ctgtccagta tagggcgact ccacctggcg cataaactgc
    16261 aaagataaaa atcaagactg gaatcccata catcatcgca gtcgtagcgc catttcgctc
    16321 agacaaagct ttgttggaca accaagtact taaaaaggtg aatactgctg ctaaaatcgg
    16381 aagaacaagg gttgtatcca cactaccaag gttaatccat aagaaatgac ctgtctttaa
    16441 aaagtcaact cttgataggg cttggaacag ggccaaaata accggcatct gaatcaaaat
    16501 cggccaaaga gagtctgact gtctgacacc catttcttta aatactttac gcatttcctg
    16561 ctctagtttg gttctgcttt ccatatctcg acctggatat tgttctcgaa gcgccttaat
    16621 gcgtggctga gcttcctgca ttttcctaga agccaccatt tgcacctgaa agactggcaa
    16681 gaggactgta cgaatcaaga ccgtaaagag aataatcccc actccgatac taatatcaaa
    16741 cgataaaaag cgaataattt ccgcaaagaa gtaaaccaat ttactccaaa aatcagccga
    16801 ttcggctgta atatcgctag ttaccccatt agtcgcacag gctgtcatga ttaacagaga
    16861 cagtcctagc aaactagtca actttagttt ctttttcact cccatttcct tcccggtaaa
    16921 tctttgataa ttttaataca tggagtagat ttttctccat ctctgcgtat cccaaggttt
    16981 cgactccttt tcgagcaatg acaacaaagt cgacatcttc taccagactc ccttttgcat
    17041 tctggataat atgccgaatc cgtcgcttaa tttgatttct agtgacggca ttccccagtt
    17101 ttttgctaac tgatagacct actcgaaaat ggtttttctg gttttctaat tggtagacca
    17161 caaatttgcg attagcaaaa cttgtcccct ccttgaaaat cgccttaaaa tctttctctc
    17221 tttttacacg aaagtttttc ttcaaaactc aactccatct attaaattac tactattata
    17281 ccatattttt caaaaaagcc aatcatagca aggttttgga caatttcatc agaaaaagaa
    17341 gctggaaaaa taactttccc aactccttgt attgaatatt tttttagttt cacttatttt
    17401 ttcaagcgtt caacgtcacg ggcaatgact aattcttcat ctgttggaat aaccaagaca
    17461 cggattttag ctgcctctgt tgagatgtct cctgtaacgc caaagacatt cttttcatca
    17521 tcaacatcac aactaaacca cgaaatccct gagattacat cacgacggaa actctctgca
    17581 ttttcaccga cacctgctgt gaaaacaatg gcatctgctc catttagcac tgcaaggtac
    17641 tgaccgatat gtttttggat acggtcaaca tacatttcat aagccaagct agcctcgtga
    17701 ttcccttctg ctacagctgc ttctatatcg cgcatatcgc tagaattagc agaaactccc
    17761 aaaagacctg attcacggtt aagaacacga ctgatatctt ctggtgtgtt aaaatcctct
    17821 gtatattgca ttaaataagg aatgatagct ggatcaatat cccctgtacg cgttcccatc
    17881 ataataccac caagaggagt gaaccccata gaagtgtcta cagatttgcc ggctttcaca
    17941 gctgtaattg agcctccgtt accaatatga caggtaatta acttcaagtc ttctaatgga
    18001 cgtcccaaga gttttgcagc ttctcctgct acaaactggt gacttgtacc atgagcaccg
    18061 tatttacgaa ccttgttttc tgtgtaatat tttgttggta gagggtagcg ataagctttc
    18121 tctggcatac ttgtgtggaa ggaagtatca aaaacaacta cactggtaat gtctggcaac
    18181 aattccttga aggcacgaac acctgctgca tttgccgggt tgtgtagagg agccaacaaa
    18241 ctcaactctt caactttttc taaaacatct ccctcaacaa ctgttgattc tttgaaatat
    18301 tctccaccag caacaacacg atgtccaaca cctgtaatct cgtcataagc cttgataata
    18361 tcgaaacgaa tcaagtcatc caataaaatt ttaacagctt gtgtatgatt ttcaatatcc
    18421 aaaatttgtt gttcagaacg gccgtcaaat tttacagttg aaattgaatc tttcaaaccg
    18481 atacgttcaa tcaaaccttt cgccaatact ttttcttctg gcattaagta taattgccat
    18541 ttcaaacttg aacttcctgc attgattgca attgtttttg tcataacatg ataccccttt
    18601 ttaagcgttt tcaactatta taacaaaatc tattttatat ttcagtacct tgagtccatt
    18661 tttgaaaatt ttctttaaat ttcattaaaa cacttgcatc ttgcaagcta gcaagtggat
    18721 aaacaaaagg ctctactgct atttcacttt tcttctgtag gataaaaata gtcttagatt
    18781 gtttagcatt agcaaagaga ttttcaggta aactaatcat agcaaccaga cttgcctcct
    18841 ctttcaacca gactttcaac aaattacttt gaggactggt caacaaatca ctcggagcta
    18901 gaaaaatagc gtatccgtct gacttgaggt acttaagtcc ttgttccatg agcaagtgat
    18961 gggtgtaagt atgttcttga ctagaagcaa cttgatggcg cgacgcaacg gcatcatcag
    19021 gataatagcc aacaggcaag tcgctgatga ccacatcact ttctttgagc atttgtggac
    19081 gaacggcatc tccttggaca aagccagcct gcaaaccaat tacatctgcc atgctagctg
    19141 ccaaatcaat cagcaaatca tccacttcca ttcccaaata atccaccttt ttagtaagcg
    19201 aggtcaagaa agtagcgccc aaaattccca tcccagaacc catttcgagg atagtaattt
    19261 cctcctcttt aaacagctct tccacaataa acaccaaaag taaagcaata gcatccggtg
    19321 taaactggtg attggcctgc aagggttctg tttgcccagc cttcatcaag agaaactggt
    19381 aggtcttgag ccattcttct ttgcgtagtg ctaaacgctt aagggtctga ttgttgtctt
    19441 tgacctgttc tagctcagtc tcaccatcca gatagatgct gttttgctcc accaaggcgt
    19501 cataaaagtt ggtcgccaaa tcactttgga tgacttggac attctctagt aaataggtat
    19561 aagcttgttc aattttttca aaatccatat tcctatctta tcaaatttcc cttctttttt
    19621 ccattcttat agaaaaatca ctccctgact aggcgagtga tttttgggct actattaaaa
    19681 agaattctga gtgatttcct tgaaacaggt cttcagcgct atagagaatc tgactatgca
    19741 cagatgaaaa accatgctca attagcttgt tttccagttc agctaaatca aatccatgat
    19801 gattagcttc tgtcttggta aaatcagcaa tgatgagttt cccatcttcc ttcaaatgtt
    19861 gatgaaacag tgagagagcc gcatccaaat caggcatatg atgaagaacc cgactaacag
    19921 caaggcaatc aaactctttc tccaagggat ttttcggtaa atcttgctcc aaaaactgga
    19981 tattcttgat tgcttgctgc tccactttca aacgagcttg ctccaacatt ttctcagaaa
    20041 tgtctacaag agtgactgac ttagcctgct tggctagggg ttaggggcaa ggctaataga
    20101 cccgtgccac caccgaaatc taaaatttct ttgtatgata gaagatcaat ctgtttctcg
    20161 gctgcttgac ataccaagtt tgcgaggaag atatttttag ggaaatcgaa agtttctgct
    20221 ttgtggttaa aatcatgttt catatcttta atttagcaca aagtatagta aactgaaata
    20281 agatataaac aaatgaattg gagcttaaca tccatttcca gcaattttct agaaactaca
    20341 gtggactatt ctggattcaa cgcattatag ttgaattgac taggaattct ctttcttttc
    20401 aggcttctct tctgattttt tcttctccac tttttcgctt gaatcggtcg ctacctcttc
    20461 ctttttatct cttttctctt ctttgatttt gactgaagga aacagaaact catattggct
    20521 cttatccgta cgaaccctcg tcactaagcc agttttcttg ttttgatagc ttacctgacc
    20581 tagattaaaa acctgttccc cactttcttg ctcaacctta tctttggttc gtttagccat
    20641 agcaaaagca accaattttt ctttattcaa agcatagtct tgatagtggg cgacttgtcg
    20701 gttcaaataa aattgcaaca aaagactaaa gatggctgct atggtgactg cgtagaggag
    20761 aacacctgcc ttaacttttt tctttttcca cacgatagat gaactccctt tctaagcctt
    20821 tttgaaactg gaaacgaaaa tgaaccagtt gattgtcctc tgtaatctga gctgatttga
    20881 ggccataaac cataggctga taacctcgac cacgagcatt cgttttacga aaatcgtctg
    20941 actttgactt accgatggcg atgtccttgc catcttgctt catgtatagg cgattgcctt
    21001 ctactttttc gaactgcgaa cggtctaatt ctgcctcaag ttggtccaca aacaagagcc
    21061 actccttttg ctcgctttgt tgctggtagc gaacttctga aatgaggagc tgactcatag
    21121 tttgaaaaag gagtaatccc ccactgatga caatgagggc aagtagggat tctaacaagg
    21181 taaaagcctt gaccttatgg ctctttgatt gccaacaact gttctgaacc atggtagacc
    21241 tccaatcctt tttcactaga aaatacctga atctcaactc cgttgatgct tacctgattt
    21301 tgccccgtct gcagggccat cttagctacc ctcaagactt cttccttttg caagattttt
    21361 gcttcctctt gcctattttt ttgaatttgt cccaaaagga gggtcgcaat gctggcaaag
    21421 atagctagag cgactactgc ttccagtaaa atcactgccc taattttttg tttccttaat
    21481 gcgtttaatt tttccatttc ctagatataa ttgatagcga atcgctcctt tactggtctg
    21541 aaattcaacc ttagccaggg acgaattgcc cccagctcgg tcaaatgtaa tactttggcc
    21601 tgatggtgcc tgaattcctt taggaactgt caacttttga ctgccattgc taagcgtctg
    21661 cccatctaaa tttagattag tcttttgctg actggctaca ctgcgttttt gggtttcccg
    21721 atagagttct tcaaactcca taaagaaaat ctgttcctct accgccgcaa aagtggactg
    21781 aacagagccg gacaagccca aggcaaggat actcacaaga cccaaaacca agagactttc
    21841 cagcatggta aaggccttaa tcattgactt tacgatttgc tcccacattt ttatcattgt
    21901 attctttata agctttagcc tgttcttccg tgatgcgtcc atcttctttt aacttgctta
    21961 ggctagcatc ttcattcttt tccaagctat aaagttctgc ctggctttcc accaccttaa
    22021 caacagctgc ttttcctttg tcattgactg cttctttttg cttggtcaga ttaggtacaa
    22081 agagcaagaa aagcacgctg ataatcagca agaccaccaa catctccacc aatgtaaaag
    22141 ctttaacctt agcttttttc aagaatgtca tcattttttt cattttaaaa atttacctcc
    22201 atattttgat acatgggcat gagcattgcc gcataaagta aaacgataat cagtgccaca
    22261 aagataaaaa ccagtggctg caccaaattc atggtgcggt tgactcgggt aaaaaaggct
    22321 tcccaagttt tttcagcata gatttccaac tcactaccca gcttggactt aacttcccca
    22381 tactctatga tgagactcaa ttccttccta aagaaaggat aggttcctat cgtctgagaa
    22441 aattcacggc catttttcag ggtttgagcc agatcttgac cgatttcttt aaagagctgg
    22501 gaaccttgtt cctgcatcat ttgaaaaatc tgcgtcagct ccattccctg tgaaatcata
    22561 ttcccccatt cacgtgcata ataggctgtc aagtaggtct gcacaaagat tccaataaag
    22621 ggaaggcgtg ctaagataga aaagacactc atcttagaac ttcttttata aaaagttagt
    22681 gctaaaaggg caagcacgga aacaagccct accatgccta gaaaaatttg tggcagatta
    22741 ccgataattc gggtggcaat attgctacta tccagttgtg ggagcaggta attccgtagc
    22801 cccagcataa ttaagagaag aaaacccagc aaaatcaaag gataggtcgc tacttcaatt
    22861 aactttttct tgaccttggc cagattgtct agatattctt ctatctttcc caaactcagg
    22921 tgaagattgc catgaacttc agctagagat aactgagtga caatggtact tgaacatccc
    22981 aaactttcca tcatttctga gaatgatttc ccctgagaca agcctgtacg catctgggtc
    23041 acacactgct tgtccaacaa ggaactccta tctaaaaagg agatagtctc caccagatga
    23101 aaaccgctag aaaagagatt gttaaatagg gtgatgatat ttttttgctt agctgtagct
    23161 aattttttcc gtctcagcct gaagacttgt gatatgtcca tctttaagaa gctggtcaat
    23221 ttgctcattc cacttggctg cttggtgttc ttgataatct ctgtttgcaa agtcaacgat
    23281 tcctcctccc ccgattaatc tctggtagca gactccttgc agaacaactg ccaattcttc
    23341 ttcactcaca cccaactcca gcagacgctc ataaacacct cggatactct tggcgtgaat
    23401 ggttgaaaag actgtcgcac ctgtcaaact agctctgacc actgcacgcg ccgtctcgat
    23461 gtcacgaatt tctccgataa tcaagagatc tggtcgatga cgcaaggaaa gtttgattag
    23521 attttcatag gttagaccga ttgcttcgtt caactgcaac tgaagcatgt cgtcctgctt
    23581 gatttcgaca ggatcttcga tggacataac ttgctgtcct ttaaagagtg acttggacaa
    23641 ttcatgcatc aaggtcgtct taccactccc aaccggacca gcaaaaagat agagtccccg
    23701 ttgcctgtac tgcttgccta attcttcaat atcctgaaac caaaaatgca agtcctgctc
    23761 ctcatcgtgc aacaaacgga taaccaaact ctcatgcccc cgataatcgc ctacagtaga
    23821 taaacgtaga gacgccatct tctggtcata ggcataatca caggaaccca gttgactacg
    23881 tcttttttct cccacattca tacccgccac aaacttaaag tgactgataa cggctgcaaa
    23941 cttttcaaaa tcatagctac caattttaca gcgctcgtct cctaccctca tatgaagctc
    24001 ataggcgtct aacttgggga caaaataaat gtcttgcgcc ccttttttcc gagccgagcg
    24061 aatgatttct tgtgcaattt cttgaaccat acttacctcc tcacctatac tattcgcaaa
    24121 gcgttagaaa aataaaaaaa gcaactccaa aaaagttact tttctctatt ttaatttcat
    24181 acggcaagaa cgattccttt cctgactggt ttgtttttca tagcctgagc gtagtttttc
    24241 gtctgggata acctgctcat cctgcaaaag agccaaagaa tggtattgtt gtaaatactc
    24301 atcacattca tcacaccagc gttggtcttc cgggtcccaa aaaatggtca tcaagtcgct
    24361 tctactttta taaagagggg attcttgttc caatctaaac cagcaagttt tgtagtattt
    24421 gagagcatca taatactggt caaattttct acttgctaca atatcttctt cccaaccttc
    24481 taagaaccac cacggttcaa aatctccgta catttctata acacgataca tattcattca
    24541 ttcctttgta ccgtatatta taaccaattc cgccagacaa ggaaagaaat atgctcattt
    24601 cttaattttt tgataaaaaa tccagccatc tgatggatga ctgaatttct atttacttat
    24661 gtacaaaaat atttttacta cttaggcttc tgagatatcg ttttcgataa tgaccttaat
    24721 ggcatggtgg tctgctgcct tactgaagac ttcgtaggct ttttcaattt cactgagttt
    24781 gaaatagtga gttaccaatt tttctggttc aatcttatga ctttcaagcg ctttcaacaa
    24841 ttgtggagtc gtatttgtag ataccaaacc agttgttaca ttgatgttgc gaatccaaag
    24901 tttatctaaa tcgaattcaa ctggtttacc atgcacacca cagttggcaa ccgttccgtc
    24961 tacaccgata atcttttgac agaaatcaaa tgttgcagga ataccaacag cttcgatagc
    25021 gacatccaca ccacgaccat ctgtcaaatc ataaatttct ttaatggctt tttcagggtc
    25081 tgaagaatta accttatgag tcgcaccgaa tgatagggca gtttccaagc ggttatcgtc
    25141 taggtctacc ataatcaatt tagctggtga atagaattgg gctgttaaaa gagcagccaa
    25201 tccaactgga cctgaaccaa taatggctac gctgcaacca ggttctactt tcccttttaa
    25261 gacaccaatt tcatatccag taggcagaat gtctgacagc ataaccaaag cttcatctga
    25321 caagtcttct ggagtatggt aaagagtatt atctgcatga gggacacgta gatattcagc
    25381 ctgcatacca tcaatcaagt gaccgaaaat ccagccccct tcgtcttcac agtgagcata
    25441 aattcctttt ttacagtagt agcatttacc acaggcacag acgcaagaaa tcaagacctt
    25501 gtcacctttt ttgaagttgg aaactccttc cccaacttct tcaacaatcc caatcccttc
    25561 gtggccaaga atggtaccac tttggcaagt aggaacatcc cctttgataa tatggaggtc
    25621 tgttccacaa atagtggttt ttacaatacg cacaatagcg tctgttggct tgcgaataac
    25681 tggtttgtct acatcaacaa aagaagcaag tcctggttta acataagtat aggctttcat
    25741 aaagcactcc tccgtttttt tatttgtaat atttatagtt caattataag cctttttctt
    25801 tgtttcttca agcttttttt gtgatttttt taacttttta tttaccagta aagtaccctg
    25861 cataaaaaag cagaagttag tctctaactt ctgctttctc tcttatgctt gataacgttt
    25921 tacgccatct aggtaggttg ctaccaattc caaatcttta tctaatacga tgaagtcagc
    25981 gtcgtagcct tcacggattt ggccacagac gtcatcgatg tgaacggatt tagctgggtt
    26041 gaagctggcc atcatgactg cttcatgcgg attcgcaatt ccccattcga ccacattctt
    26101 caaaccatct ttgagtttga ggatagaacc tgccaagtta cctgtcgatt tgaggcgtgc
    26161 agttccattt gcaacgacaa ctgggaattc tcccaacata taatctccgt cttccaatcc
    26221 cccagctgtc atacagtctg tgataagagc gatgttttct gttccttttt gtttgataag
    26281 aatttcgcaa gcctttggat ctacgtggtg accatcacag atcaactctg cataggtatg
    26341 tggcaattgg tacatggctc caaccatacc caattcacgg tgagtcaacc cacgcattcc
    26401 attgtaggca tgcacccaaa cactcgctcc agcatcgact gcttttttgg cttcatcaaa
    26461 agtcgcgttt gaatgtccaa gagcaaccgt cacaccttcg cccgtaactg tacgaacaaa
    26521 gtcttccacc ccatcacgtt ctggtgcaag ggcaatttta ttaagcaagc catttgccgc
    26581 tttttgccaa gaatgaaact cctcaacacc cgggtctctc atataagttg gattttgtgc
    26641 ccccttaaaa gtttctgtga aatatggacc ttcataataa atcccacgaa tcttagcacc
    26701 tgttgcttct ttataatggt ttccaagatt ttcagtgact gcaagcaatt gctcataagt
    26761 ggctgttaaa gttgtgggta agaaactggt aacaccggta ctaagaagtc cttcactcat
    26821 agtatgcaat gtaccttcaa tgttgttgtc catcacatct acacctgcat atccatgaat
    26881 atgagtatcc acaagacctg gggcaatgct ataacctgta tagtcaatca cctcagcccc
    26941 ttcaggaatc tgctctacat gtttcccaaa cttgccgtcc acaagttcca agtaaccacc
    27001 tcgacgaact ccgtgtgggt agaaaaactg atccgcttta atatagttag gcataatgtt
    27061 aacctcctta aaagattgat tctacaattt attatgtcaa ttacattata aacctttctt
    27121 ttttatttgt aaatggtata gacctatttt ttggagatat tttaaaagag ctggatttct
    27181 ccaactcttc tcttttttaa tacaagttat tttgatttaa ccggcttgtc ttgagctgtc
    27241 tgcaaagctg tggcaatcgt atctgcatac aattttgctc ctgcttcgat agtgctactc
    27301 tcactcccga aatgaacctg gtctgttcct gcccaaattt ctggatgctc tttcgcaact
    27361 tgattccaat ctgctatcgt aatgtaaggt gtcttctctg ccaattctct catataggca
    27421 gcagccttct caacgatggc ataggtctct tttgtcttat ctccctcata aggagtcacc
    27481 aaaattatat ggtgtccctt aggaagattt ttcacgatac tgtcccagtc atccttgtaa
    27541 ttctcaggat tatttacccc agtcgcaatg accaccgtct taggtaaaaa tttattctgg
    27601 ctattattta gcatgatttc atttgcggtc ttggttgtta cgctgacctg cgcgttaatc
    27661 tgtgctccag gaagagctgt ctgtagtgct gtatttgccc ttaaagccac tgagtcacca
    27721 attaacatag tgccatcagc aattcccaaa ctgtttgcat ctgcccgttc tgccatcacc
    27781 ttggtctggc caatatttgt tgcagcttgc ttcaagccat tgacagtcaa gtctgtctca
    27841 aacgctccca cttgtggtgc caacaaggtc accgtgcaga caatgatggt caagattcct
    27901 gtacctgctg caagaattgc gtgaatataa ggcaggggac gaagggtttg gacaataggt
    27961 gtgttcttgc ctgcaatcca aggttccaat acataaaatg acagactggc aaagccataa
    28021 gaacaaatca gagtcagtaa tacagcaaga agatttgatg tcaactgtga gaaaatgata
    28081 tagaaaggcc aatggaaaag ataaaccgca tagctagtat ccgctaaaaa gctgataatc
    28141 ttcggctcct gtatatgatg tgtcttttca tgtaagacac gcgccgccag aatcatggca
    28201 agagctgcaa gactggcaag taagaagccg ataagatagg caaaaagata agtgaatttg
    28261 acaaagaaag tcaaaagaac taggaaacca aagcctcctc caaaaactac caaagtcttt
    28321 cgtaaatccc agattttatc caactgcttg acgagggaag tcgtctgacg aacgcctaca
    28381 atagttgcta acatacttcc caaaaagaat ggatagacat gagttaaact ggagaaataa
    28441 acagaggaat aagaggtcac tagaaaacta ccaataaaca tggagaagaa actgatcaag
    28501 aaggcaacag cagataagag aaagaccatc cccttcaact gaccatttga tttagcttgt
    28561 ttggataaga accaaactgc caatccccaa agaatatagt agtgaacctc aactgccaaa
    28621 ctccaattat gaacaaacaa atgaggaatg aactgagatt cataactccc acctgttagg
    28681 agttcataga agttggtcat aaagcctaag acgctcgcaa tctggccacc aattccagca
    28741 acatagtctt ggcgaaccaa gaaagtaaaa ggcatggtca ccaagaccat caaaaccaca
    28801 ggtggcacaa tccgataaaa gcgtcttcta aaaaatccta tcaaatcaat ctcatggttt
    28861 ttagaaaatt cttcaatgag tagagctgta atcaggaaac ctgaaaatgt gaaaaagaca
    28921 tctaccccga aaaatcctcc aggaaagatc gtctgaaaga agtgatacaa gagtaccaaa
    28981 agtaaacctg taatcctaac caaggaaaac catttaatgc gcatacgagt ttattcttcc
    29041 tttcattgta cactttattc tatcaaaaaa agaagaaaaa tcctaagaga aaacttagga
    29101 tttttagctt atatcaattc cattttagaa attacgtcct gacttattat agccatattt
    29161 ttccacaaaa tactcacgga attccaagag attgtcatcc atgatggctt gtcgcacttg
    29221 cttcatcagg ttaagcaaga agtaaagatt gtggtagcta gtcaagcgga tcccaaaggt
    29281 ttcatcagcc ttgagcaggt gacgaaggta agcgcgtgta tagttattac atgtgtagca
    29341 atcacactca ggatccagtg gcgtaaagtc ctcagcaaac tgggcatttt tcacaaccaa
    29401 acgtccttga ctggtcatac aagtcccgtt acgagcaatt cgagtcggta agacacagtc
    29461 aaacatatcc accccacgaa tgaccccatc gatcaagcta tctggcgctc ccacacccat
    29521 cagataacga ggtttatttt caggcagcag ttgagttgta aagtccaaga ccgcattcat
    29581 ctcttcatgg gtttctccca ctgccaaacc accgatagag tagcctgaga aatccatgct
    29641 gacaagatca tgagctgatt ggcggcgaag gtcttcaaat cctgcacctt gcacaattcc
    29701 aaacaaacct tggtcatgtg gacgacggtg agccttcaaa ccacgctcag cccaacggct
    29761 ggtacgctct atcgatttct taacgtagtc ataaggttga taaaactgag gacattcatc
    29821 aaaggacatc atgatgtctg aacccagatt attctgaata gagatggctt tttctgggga
    29881 taggaacatc ttagaaccat ttagatgatt tttaaaggtt actccttctt ctgtgatatt
    29941 acggctatct gctaaagaat aaacctgaaa accaccacta tctgtcaaga taggctggtc
    30001 ccaattcatg aacttgtgga gaccaccagc gcgtgcaatg agttcatctc cagggcgaag
    30061 ccagagatga taagtgtttg ataggataat tcccgaaccc atctccttca attcttcagg
    30121 tgactgagtt ttgacagtgg cttgtgtccc aactggcata aacataggtg tcggaaaggt
    30181 accgtgggga gtgatgattt ctcctagacg agctcctgtg tgtttttctt tcttaatcaa
    30241 acgatatttg attggtgaat ctgacatttt ttacctccga agctgggaaa gacagtccca
    30301 gttcatacag tgtgcccaag gacacactgt atgattttat caaaaaaagt aggaactgtc
    30361 acgaactatg tataagaact atggtataat aagagaatga actatccaaa aattgattta
    30421 aaaacaattc gtcaggagtc aaaacatttt caggctgaca ccccccgtct ctttctcctc
    30481 tatatccttc ccagtatgct ggtcatctta tctagttttc ttaatccctt atctcggatc
    30541 cacgggactg ttttagaaca gccatttttc agcatacttg gccaaatact tcaagcctac
    30601 ctctttcctc tactagtctc ctttatcggg actattcttt tgaccagttc cgtctatgca
    30661 acactgacac tcatgaaaga ttctaaaacg gagccatctg taaaaaacag cctagctctc
    30721 tttgatgagg agcgcttttc tcaaaccttt ttgaccctac ttctcaaacg tttctatctc
    30781 tttttatgga gtatccctaa tttacttggg atttatctcc tcttttatag tagcttttta
    30841 gccaaaaaat tcgtcaccct acatcctgag tttccaaatc tagatctctc atcagttgaa
    30901 accgagcgtt tcctcatggt ctttggactc tactttcttg caagtctcat cttgatcatt
    30961 gtaggaaata tcctctatat tccacagtat tatgcctatt cacaggtgga atttcttctc
    31021 tgttatagtc tagacctagg acaggtccca ccaagacgaa tcctaaaaac tagccgttcc
    31081 tttatgaagg gctacaagtt ccagcacttt atcctagatt tacagcttct tccttggtac
    31141 ttcctcaatt ggattacctt tggcattgct agtttttcac tcctacctta tatccaatgc
    31201 actaaaatta tgttttaccg agcagtattg gctcgaaaac gtccaaaagc ttgaaggttt
    31261 ttcccctcaa gcttttttct atcaatgagt ttctccgcct accaacttga gttcctgatc
    31321 cccatgttct atcatagcgc cgattgctgc ttctatccct cgccgaatat ccactaaact
    31381 catagttgga gtagtcggtc tgttcaccac ctgttccatc atataaggaa tatgcataaa
    31441 acctgcctta acatatggaa atttcttttc taccaaatag agagcctgat acatcaaatg
    31501 gctgcagaca aaagtccctg ccgtattgga aacagaggcc ggtaagccct ctttttttat
    31561 agcttgaacc atcgctttaa tcggcaaact actaaagtag gccgaagcac catctgggcg
    31621 aatgggacgg tcaatcggtt gattatcttc gttatcagaa atgcgtgcat cgtcttgatt
    31681 aatggccact cgttcaggtg tcacactagt tcttccacca gcttgcccaa tacaaaggac
    31741 aaagtcaggt tgataacgat tcatctcttc ttccaatact tgagcagatt tgtgaaaaac
    31801 tgtcggcacc tctagccaac ggacctcagc accatggatt tcagctggta aacctttaat
    31861 ggcctccaaa gttggattgc ccttttcccc tccaaagggc tcaaaacctg tcactaatac
    31921 tttcatttct aactcctcaa aaccaattca atgagacttt tttcttaaaa acaagtataa
    31981 catatttccc ttattctgga ttaaaaagga ttagcgagat tagaatcgac cttcaagtgt
    32041 attttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg cttcaaaata
    32101 atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa taagacaaaa
    32161 atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa gactcctagc
    32221 agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg agccaattct
    32281 tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat actttccaaa
    32341 taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt aataattgac
    32401 atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat ttaataaacg
    32461 gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct taaccttgat
    32521 atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag cctctaccaa
    32581 cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg tttccaaaat
    32641 cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa tcgccatttg
    32701 gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca aactaatccc
    32761 aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt gatacagtaa
    32821 atcttgaatc tctagcattt cttcccctct ctttttattg atttatcaat agttgactaa
    32881 ttaattgtga tataaagtaa aatagattgc aagaatgttg cttaactcat tacaagatga
    32941 taactttcca ttttccattc aaattgatac tcaatgaaaa tcaaaaagca aactaggaag
    33001 ctagtcgcag gttgctcaaa gcacagcttt gaggtttcag ataaaactga cgtggtttga
    33061 agagattttc gaagagtatg acaaagaaaa aacgaacgag aatcgctttc catcacgaaa
    33121 gctagatctc attcgtcaaa atgatgttat caagtcgggt ttatccattc attgaaacgt
    33181 gaacgtgatc atagtgattt tctgtcacac taccacggtc tggcattggg ttccaagtgt
    33241 tagctggccc atatttgcta tcgaatggag catagaaacg ttgtttccag atgatgtaac
    33301 taatgccacg gctggccata ttttgaatag catattccgc aatcttatcc cctaattctg
    33361 aacgttctgg taccataaag tcgatagcca aaccttttcc gtgatctcca ctgtctcctg
    33421 gacgataacc actaaaggat gtaatgccaa acaagttagc aatttcttct ttaaaggcag
    33481 ctgtttgtgg ttgaagacct gcattttcag attttgctac tgcaagtcca gcataatcgg
    33541 gcgcagctgg agcctcgtaa gttgttgaaa ttactttcgt ctcttctggt tgataagtag
    33601 aaactgctgc tgtagctcca tttgatgatg ctacttcttt tgcttctgaa cttgttgtag
    33661 ttacttccac tgctgatgca gcttgagggc ttgcttgtgt ttcctgcttc tcagctggag
    33721 tcgtttcctg aggagttgct tcttcaactg ggcgagttgt ttcggtcgtt tgctcctctg
    33781 ggacagaagt gcccgtagat ggtgccactt cttcagaagc aatcactgtc tttgtaactt
    33841 ctgcaattgg ttgagaaagg tctgcaacct gaacagtttg atcatcaacg gtcacttgat
    33901 tagtggtcaa atctgctgtc gcagttgtca cttcttcact agagtctgct tgaggtgttt
    33961 ggatttcaac ttctgttact tcttctgctt cattgacagt cgttgtcaaa acagtttctg
    34021 ggaaaatcaa gtccatatta gtgattttgt tcagattcgc aagcactgtg acatctacac
    34081 ccaaggcttc tgcaatggtg ctcaaagtat caccatactg tacggtataa cttgttttgt
    34141 tgtccgtttt agtcaaatcg ttttggattt gctcaacact acgtgcagtc caaagaactt
    34201 cttctgcttg agttgccaat actggggcaa atgacaaggc tactgttgac gctaataaca
    34261 ttcttttctt cattctttca aattcctttc aaatgagtac ctgtctatca taacacaaaa
    34321 aatgtagaaa aaaagccctc tcgggcctat ttaacagaac tgtctattcc ttgtaacaaa
    34381 ctaggttact tgaaatagtt tgttaggtct ctgtcacaaa actgacacaa tctttttatc
    34441 acttagtctc aaaaatacgg gaaatatctg ctaacgcttg aatcctgtga ttcccttcat
    34501 aagtagactc taaaaagttg atgctttgaa tcccactatt ctgggcaaat tccacatcca
    34561 gagtccgatc ccctatataa taagtattat cagaattcaa ctgatactta tctagcagat
    34621 aggtagccgc ttctggactt ggcttccgca caaagccact ctgactggtt aaaatctctg
    34681 taaaatagga ttccaccccc aagtccttga gaatggtaaa agcgttgttc cccttatgag
    34741 tatatataaa ctgctgaatt cctgattcgt ctgcccaagc tagcacctca cgcgcacctg
    34801 gcatcaaaac tacctgagca ttcttctcag ccagactctg ggcacgcacc tgatttagca
    34861 cctcaacatc cagatttcta tcttctgcca cccgcacaag caaatcttgc accgaatact
    34921 tgaagataaa ctctctcacc ttctccttat cataaggaat agaaaactga gcaaaagtct
    34981 cctcaatccc tgataaaatc gcttcgtaag agtccaataa agtcccgtct aaatcccaaa
    35041 taaaagctgt tttttgcatt tcctatcctt tcaagctcat atagcgctgg taacgatagc
    35101 gtagaaataa ccagcgaaaa ccattatcca agagagaccc tgcccaaata ccaggcaagc
    35161 cccaaccaag cacaatcccc atcagatatc ctgtcccaat gcggatacac cacattccta
    35221 tacttgtcgc ataaaaaggg aggcgtgcat ttcctaatcc ctgccagact gccgtataga
    35281 tgactgttcc tgtcgtcata ggggtcccaa gtagtgaaaa cagtgtcact agaacactag
    35341 cctccaccgc tagagaatca gtcgtataga gatgagttaa tggtacaccc aagacatata
    35401 tactaaagga caggggcaac atgaggaaca gagaaagcca aaaggtttgt ttactcaaac
    35461 tagcaactct tttccaatca tcctctccaa ctgctcgggc caacagcatg accgttgccg
    35521 tagcgacgcc aaaggcaggc atatagttaa actgggtcaa gacttctccg attgcattcc
    35581 cagcaactgc ctccgtccca aaagaaacga ccaaggcaat gatcactaca tctccagccc
    35641 tcatcataag tcgctctcca gctgctggta aagccaaggt caacagttcc ttatctaaac
    35701 caaaagttgg cttcccataa ggcagtttta attgtgacca caaaatcaca agaccaacca
    35761 aacgagacac aattgtcccc caagcaacac cagctatccc catatccaga acaaaaatag
    35821 ctagacttga aaaaagaata ttcaaggcat tggataaaaa actaacatag agaggcagac
    35881 gtggattatg cgttgcacga atcaaggctc ctagactagt cattaaacct aagagaacaa
    35941 tcgatccgcc taccaaagat agatacagtc caccactctc agctacatcc ctctccgtcc
    36001 ccaaaagtcc tatcatctct ttcccagcga agatggacaa aaatcctaaa aggaaactta
    36061 atagtaaggt aatcttcaac gcctcagtca catgataggc caacttcgac tggtctttct
    36121 gccctatgct ttttgaaata acactggaaa tagcagctcc cagagcgatg aaaatcgcct
    36181 gataaatggt gataatatta ccagctactg aaacccctga aatagctatc aatcctaaat
    36241 gagcaaccaa ataactgtcc accattccca ttagcatctg caaaaagttt tcacccatag
    36301 ctggcaatgc aatattaaga atgtctttat ttttcttaaa caatctctcc tcctgatgaa
    36361 aagaaactca gttggtttcc caaccgagtt tgctccctct gtcttaaagt cctaaataag
    36421 cctcaaccgc tgcttgcatg tcagcagctg ccactgttgt cttgtgacga attggagcta
    36481 tttcaagccc atcaactgct ggtggcactg caacgcctga gatttcatgt aattgagcca
    36541 aggcttcaaa gtctgttaaa cctgcttttc cagttacagc ttctactgca actactggga
    36601 acttgtatgg actagctgtt gaagcaatca ctgtcttagt tacatctcca gtggccgatt
    36661 ggtatttttt ataaactgct gaagcaacag ctgtatgagg gtcctcgata taagaatcta
    36721 actcacaaac acgcttgatc tctgctgccg tttcttcctc agtcgcatat tcagctgcaa
    36781 agaggtccaa aatctctgca tcaaagtctg tcaacttata ttgtccttgc gtgttcaagg
    36841 cattcataag ttcagttgtc ttttcagcat tatttcccaa aagatggaaa atcaagcgct
    36901 ccaagtttga agataccaag atatccatag atgggctggt tgttacctta aactcacgtt
    36961 ttttgtcata gacacgtgtt ttaaagaagt ctgtcaaaac attgttgtca tttgaagcac
    37021 agattaattt accaactggc aaaccaattt gtttggcata aaaggcagcc aagatatttc
    37081 caaagtttcc tgttggtact gtgaagttaa ccttttcacc agctacaatt tcaccagtct
    37141 taaccaattg agcgtaagca taaacataat aaacaatttg tggcaccaga cgaccaatgt
    37201 tcatagagtt agctgatgaa aattgcaact tgttggtagt caatttttca cgaagagcca
    37261 cgtcgttaaa catgtgcttc acatttgttt gcgcatcgtc aaagttacca tcaatagcaa
    37321 taacatgagt attgtcgcca gtttgagtgg tcatttgtaa ctcttgaatc ttgctgacac
    37381 catcctttgg ataaaagacg ataatctcag taccaggcac atccgcaaac cccgccatag
    37441 cagctttccc cgtgtcacca gatgtcgctg tcaagataac aatcttgttc tccaaaccat
    37501 gtttcttagc agcagtcgtc ataaagtatg gcaaaataga caaggccata tccttaaagg
    37561 caatcgttga accatggaaa agttccaaat tgtattgccc atctaatttc actaatggtg
    37621 caatagctgg agtatcaaat ttgctatcgt aggcattgtt gatacagtag tccaactcct
    37681 cagctgtaaa gtcatctaaa aatgctgaca aaactagctt agcaacttcc tggtaagaag
    37741 tatctttcaa tttgtcaaag tccaaatcta cctttggata agtaaccggt gtaaacaaac
    37801 cgccgtccgt cgccaaacct tgcaaaattg cttggctagc agttactgta ttgttggcat
    37861 cacgcgttga ttgataaact aatgtcatta ctctctatcc tttatctata gtctcgtcca
    37921 ttatatcatg atttttcaga aaattctccc tttataagag aaattatagg ctcaattctt
    37981 ctctcaaagg ctgtaaatag gtcatttctt ccttatttct caccactagt ccctcctcag
    38041 ctagtaggag taagtctttg gaaaattcaa taatcgtagt ttcttcctca tctgtaagat
    38101 ttttcttaga aaattgtctc cttaaagact tgtaatcata accaaatact ttaaagaaag
    38161 gtgctgtttc taagtaagct tctaacttgt ctaaattaac caataatccc aagtgaaaag
    38221 ctgcagaagc aaaagtccta tcaagtggct gtgtacacac actacgaaac tcaactgttc
    38281 ctcgagtcgt taagtcttgg tactggtaac tacgatgagt ttcaaaatcc ttctcttggg
    38341 gggaaataat aacctcatcc ccattcagag caaatgcttg gatttcaggc gtagccaaat
    38401 agtccccagc ctgaatagga taaaaataat aggtctgccc atcacgttcc gcagtaaaaa
    38461 tcgcagaatg atttagatag tcaaaaaaat cagcttcatc attaaggagt ctagcattga
    38521 ccccaacatt ctctggatag ataccatgca tagattcttc ccagaaaata tcccttgaaa
    38581 ttttcgtatc ccaatccgca cccgaaaatt cagagtttgc aaataaataa gccttagccg
    38641 cttcaatttg agtaaaagca ttaatcaccc gtaagtagtt ggtttttgaa atatccagct
    38701 gaacctggct cccacagata aaagtaccat attcagggaa atgatgtaaa tctgatttaa
    38761 taatatttct actcaaattc aaataatcca tcaacatctg atagcgtgga taagccactg
    38821 gacaattctc atttttatcc cagttgggat ggataccaca gccaacaata gcatgatttg
    38881 attcagctaa ctttctctga attacattca tataattatt gaaacgattt tcgacctctt
    38941 gaatcgtttc agccttacca aatgcaaact caatcgttgt ataggaaact tcaaataaaa
    39001 tagcatcctg acttatcgga tctactaact ggatcagatt gccaaaatca tctacctttg
    39061 ctacggtgag atccaaagta gaaactaaat aatgaaatag atcctttata acttcaacat
    39121 ctgtagcatc cccttctaaa cttgcaacag gatactccaa ctcaattccg acaaacaatt
    39181 caggattttc tttaatattt ttcaaatacc gatgttttaa taaatcgata gaacaagaca
    39241 tactacccta cactttctta atctaaataa aatttgaata actataatta taccaaaaat
    39301 aatataaaaa aagaacgaag aataacaacg ttcctaacac tatactatac cggcggccgg
    39361 ggtcgaaccg gcacgtcctt gcggacactg gattttgaga gcagtgaaat tagcagactt
    39421 acgtcataat tcagattaat tcaatgtttt aagaaattag ttatactata aaaacaataa
    39481 ttattttagt ttttagtaat tttttaggaa ttcctatctt ggatttgatg ccttatttct
    39541 ttacttaaat tttttaggtc ttcaccatta catagttttt ctccaatgag tttactaaag
    39601 gtaaaagact taataacttt cttgagactt tcttcaaact tgccatttag aagcttcaaa
    39661 tagctttcaa aatctgatat cactctcgtt ttgacggtct caaagtcttc gtcttcagta
    39721 atttcataat tgactgatat ccaatatagc attttctatc tccttattta gttttattat
    39781 tactagttta ttatattttt aatagaatgt cgcaatttaa ttatatagaa tttaaattca
    39841 aaaatattgt tgacaaatag aaaatactgt gttaaaatgt ctatataaca gagacagttg
    39901 gaggtataag aatgagtcgt acttatataa atataagact tgcatacgaa accaagtatt
    39961 ggttagaatg tatacaagaa gaggttcaaa aaaaattaga tgctttaatt aatgaacaag
    40021 atatagagga gttagaatca atcatcacta ataagttaga aaaaaaagat tctctattgg
    40081 gggctgtttc cataacaact tttttcaagg tatcttcttc aagcgtgatt gaaaaagcct
    40141 ataacgagac aaaaaattac actacttcag aatggcgaga aattgcaagg caaatgaatt
    40201 tggcaaaagt taagcaaaac atggaaattg ggacgttaac acctagatta tatttagata
    40261 ataatattat ttcagaatta gagaagtatc aatttttatt caaaagtgat gatatgataa
    40321 ggcaggtaag gatgagctat gttattaaaa tggtcgcatt tgcctactat aaaaaattgt
    40381 ttgcatgatt tataagctcg ataataagag cttataaaaa tacaaccttt gtctgtgtta
    40441 acgagacttt taaacttttt aatcggaagg agaatatttt gataggagcg tcacctatta
    40501 tttatttgac aacattaaat aaaaactaat attaaaaaaa tataaaggag gagcagaaat
    40561 gccaaaatta ttagagactg aaaaatacag tttagatagc attatagatg gagggaagct
    40621 tagaatgatt tctaagtttt gcccagactt acatggcttg aggtacgaat tcaaaacatc
    40681 agactcaatt actaaagaat attgtaaaaa aatacgtcaa gctttaagag attctgatcc
    40741 agaaggaaag agtggaaaaa aatgtatgat gagatataca atagatattt taaatgtatg
    40801 gaacacgcta tgtagaacac gagattttat aacggggagt ttaaaagcgg atgatgttat
    40861 agatgggaag acagggatat acttctttga tgttaatacg tctaatgtaa ttacggatga
    40921 tgttatagaa aatgttaaaa ttaatcacaa aagcttagta cgaaatgttg atgaagaaaa
    40981 tatagaaagt atttcaaaag aaattcctaa aggtactgat atgtattatt atgttttgta
    41041 tagattaggg ttgaatagga ttaagtataa ttatttagtc aaggctctgg caggcgcaat
    41101 acagaaggat taagaatata attatataat taagggggag ttttttctcc ccttatagag
    41161 atagtattat tcttttggta tttggggtat cgtttatcaa tctcatctta tagctaataa
    41221 aaatagtcta tgtttttagt gaaaaaaata ttattttaag gagtggtgat atgtatatac
    41281 ttgtcacaaa tgggaaaagc tacgtgactt tcccttggtt gcgtgaaata gcttgcagaa
    41341 attataaagg agaaactaag gtgtttacta caaaggaact ctataatttc ctatattaaa
    41401 cgctttaact atcacatttt taataccaag aaaagtaaat taaaatatat agcagtatta
    41461 gagaggcaaa aacgtaaagc atggcatagt catattttgc tattcagtgt tccctatatt
    41521 ccacataagc aattattaga actttggggg catggagcag tacggataaa taaagttgac
    41581 gttgacagca aagaaaatcg cggtcgatat gtcacaaagt attttgaaaa aggtattgga
    41641 caagaattgt tggaaaactt cggaaagcaa gcctattttt catcacgcaa cttgaaaaag
    41701 cctgatgaag ataaatttta cacttatgaa gattttaact atgatagttc agtcgtacta
    41761 tatgaaacgg aatacaactg ataacccgag gctttacagt ctatcagaac aagcgaattg
    41821 gtactatacc tgctactatt gctaccgaat tactcggttt tgatgttcaa aacagtaccc
    41881 tcaaggagta aaatatggca attagaaaag gtaaagacgg taattgggta gttgatatta
    41941 gcaacggttt tgacccaata acactaaagc aacgtagact tgtcagaaag ggatatatga
    42001 cgaaaaaaga agctattgaa gcagaacact acttacgaag tgtagagtta aaagaacgct
    42061 tctatggggc taaaataact atctccatac tatatgaact acttaaggaa gaagatagca
    42121 taaatcatcg aaaagcaagc tatatcaata cacaagataa taattacaac aaacacatca
    42181 aagattattt ttctatggtc gataatgtcg gaaaactaac ctatgaagac atctaccaat
    42241 ttagagaaca tcttaggcaa aaagtagcta aaaattctga taaaccgtta agcacaaata
    42301 ctattaacaa aatcatgatt ttactcaaaa aaatttttga tgttggtttg cgaaaaggct
    42361 attactcctc caatccagca aaattgataa aaaagttgcc aattgaaaaa acaaaaatgc
    42421 aattttggac agtcaaagaa tttcagaagt ttttgacact atttgaaccc gaagaataca
    42481 atatcaaact actctttact gttctattct ttacaggatt aagacttggg gaagctcttg
    42541 ctctaacatg gcaagacatc gacttttcaa gtaatacaat tcatatcacg aaatctgtct
    42601 atgttaataa aggagtaact catatcagca caacaaaaac taaagcagga acaagaagaa
    42661 ttgttatcaa taaaaaatta agccaagaat tacaagattg ggaaaagcga caaaaacatc
    42721 tattagagca atttaccaac aatagcctaa cattacaagt gtttcaaaat agtcctatca
    42781 caattacaaa aaatgctatt gaaaagcagt acaagaaaat cattgaacgt gatagtacac
    42841 taaaaaagat acgcatacac gattttaggc actcacacgc ttccctgctg attaaccaag
    42901 gggaagatta tctagttgta aaagagcgac taggacatgc ttctataaca accacgattg
    42961 atacctactc tcacttgtac ccaagtaagc aaaaggattt agctgataaa ctagatgatt
    43021 tactataaag taattgagtt ttataaatgg aaagtttata attaaatcat ggatacatca
    43081 caagtaataa aagcacatga agtagctaaa aaagcacact ttggacaaat tgatagagca
    43141 ggaattgact acattaaaca ccctgaaaca gtagctagtt ttgtcacaac tgatgaagag
    43201 aaagctgtcg cctatctaca tgatgtaatt gaagatacta cactaaccct actagaccta
    43261 aaaaaggaag gtttttcaaa aaacattata gaagcagtcg atatactcac aaagaaaaaa
    43321 ggacaagatt atcaatctta tctcaatcta gtaaagacaa atgaacttgc tagagttgta
    43381 aaattggcgg atttacggca taattcagat ttaaccagac taccattaat tactgaaaaa
    43441 gacttagaga gaaataagaa atacagttct gctattagat ttttaagaac aaagaaaaaa
    43501 agttagtaac taaactataa aaatttataa agagaaaaca aggcttataa actttgtctt
    43561 tattactatc ttggcggtca gtctcgaact ggcacatcct tgcagatact acaattttat
    43621 taaaataaat actatacaaa gtgaaatttt ttattgagaa acttttagac taggagtata
    43681 atgtatctaa aataactatt aggtggctgt tatatgaata atgttgttac tacactaatt
    43741 tctgttcaat ttagtcaaga gttaaattct ttattaaatg ctattgttga agaaaataat
    43801 acaacaaaga ctgactttat tagacaagct gttatagaga aaattgaaga tatgtatgat
    43861 attaaggtcg ctgatgaagc ttataaaaaa tgggttgaat gtggcaaaaa aactatctca
    43921 catgaagaaa tgatgagacg ctatggctaa aatatacgca atatctgata tacatggata
    43981 cttggatgaa ttcatagacg ctctcaataa agtaaattta aacgataaag ataatcgcct
    44041 atttttacta ggagattatc ttgataatgg acttcaatct tttcaagtca tttccaaaat
    44101 aatcgaactt gaggagattt atcctaatca aattattact cttctaggga accatgaaga
    44161 atggttttat gattggttga ttttagataa gcctactgct tcagcatttc cagaaacaat
    44221 aaaaagcttc ttctctccag aggaattgaa ctatattttt aaatcgaatg ctaacaactt
    44281 tgaaacaggt gttagaaatg aaattaaaaa taatatcaaa ttcaacccat ttataaactg
    44341 gtttaaaaag cgatataggg ataaacgcta ttatgaaact gatacccaaa tttttgttca
    44401 tgcaggcatt gatgaagaag caggaatgct ttggaaagaa ctaacgagtt caaagatatt
    44461 tacaaacaaa tttccaatta ccactggtag atttcataaa gctattattt cgggccatat
    44521 tgcttcttgg gaagtagcta aagatagaag atacctaggt aagatttact atgatagtaa
    44581 aagtcattac ttaattgatg gagatgtaac gaatagcaaa acaatacctg ttctttgcta
    44641 tgatacaatt acccaaaaat atcactttct ataactttta gtcatgtgct tttatatgaa
    44701 attagtaatt attagtaaca attccaagaa atttcttatg acataacaaa aagacaaggc
    44761 ttagaaacct tgtcttttca actataccgg cggccggggt cgaaccggca cgtccttgcg
    44821 gacactggat tttgagtcca gcgcgtctgc caattccgcc acgccggcaa atagtaactg
    44881 gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc
    44941 tataccccaa taatataaaa taggcgagtg atggggatcg aacccacgca tgccagagcc
    45001 acaatctggt gtgttaacca cttcaccaca cccgccataa ttctattaac acgggcagta
    45061 ggaattgaac ccacactgaa ggttttggag accttagttc tacctttaaa ctatgcccgt
    45121 aaaatggaag gggagggatt cgaacccccg aacccgaagg agcggattta cagtccgccg
    45181 cgtttagcct cttcgctacc cttccaaaat ata
//
LOCUS       DBEJZJ010000015        44919 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000015 DBEJZJ010000000
VERSION     DBEJZJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.15"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..213
                     /locus_tag="ACL3R8_001047"
     CDS             <1..213
                     /locus_tag="ACL3R8_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR1313938.1"
                     /translation="YWKVRNIEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYA
                     VLDNTVIARDRITVPIDPLCGKDFIE"
     gene            458..1792
                     /gene="trmFO"
                     /locus_tag="ACL3R8_001048"
     CDS             458..1792
                     /gene="trmFO"
                     /locus_tag="ACL3R8_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR1313939.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1876..2613
                     /gene="pyrH"
                     /locus_tag="ACL3R8_001049"
     CDS             1876..2613
                     /gene="pyrH"
                     /locus_tag="ACL3R8_001049"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR1313940.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2622..3179
                     /gene="frr"
                     /locus_tag="ACL3R8_001050"
     CDS             2622..3179
                     /gene="frr"
                     /locus_tag="ACL3R8_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR1313941.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3239..4093
                     /gene="cvfB"
                     /locus_tag="ACL3R8_001051"
     CDS             3239..4093
                     /gene="cvfB"
                     /locus_tag="ACL3R8_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR1313942.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4102..4317
                     /locus_tag="ACL3R8_001052"
     CDS             4102..4317
                     /locus_tag="ACL3R8_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR1313943.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4403..5371
                     /locus_tag="ACL3R8_001053"
     CDS             4403..5371
                     /locus_tag="ACL3R8_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR1313944.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5564..6064
                     /locus_tag="ACL3R8_001054"
     CDS             5564..6064
                     /locus_tag="ACL3R8_001054"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313945.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6067..6393
                     /locus_tag="ACL3R8_001055"
                     /pseudo
     CDS             6067..6393
                     /locus_tag="ACL3R8_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6694..7805)
                     /gene="ald"
                     /locus_tag="ACL3R8_001056"
                     /pseudo
     CDS             complement(6694..7805)
                     /gene="ald"
                     /locus_tag="ACL3R8_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            7982..8551
                     /locus_tag="ACL3R8_001057"
     CDS             7982..8551
                     /locus_tag="ACL3R8_001057"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1313946.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8619..9269
                     /locus_tag="ACL3R8_001058"
     CDS             8619..9269
                     /locus_tag="ACL3R8_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR1313947.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9253..11493
                     /locus_tag="ACL3R8_001059"
     CDS             9253..11493
                     /locus_tag="ACL3R8_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR1313948.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLIKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSLRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPTFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11642..11859
                     /locus_tag="ACL3R8_001060"
                     /pseudo
     CDS             11642..11859
                     /locus_tag="ACL3R8_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11892..12479
                     /locus_tag="ACL3R8_001061"
     CDS             11892..12479
                     /locus_tag="ACL3R8_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313949.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12483..13664
                     /locus_tag="ACL3R8_001062"
     CDS             12483..13664
                     /locus_tag="ACL3R8_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1313950.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEAIIPTLFVIGIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYSIYSLVNQEVTIGKIQDVLFPG
                     SLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    13824..13955
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            13971..14501
                     /gene="infC"
                     /locus_tag="ACL3R8_001063"
     CDS             13971..14501
                     /gene="infC"
                     /locus_tag="ACL3R8_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR1313951.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14534..14734
                     /gene="rpmI"
                     /locus_tag="ACL3R8_001064"
     CDS             14534..14734
                     /gene="rpmI"
                     /locus_tag="ACL3R8_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR1313952.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14786..15145
                     /gene="rplT"
                     /locus_tag="ACL3R8_001065"
     CDS             14786..15145
                     /gene="rplT"
                     /locus_tag="ACL3R8_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR1313953.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15203..15583
                     /locus_tag="ACL3R8_001066"
     CDS             15203..15583
                     /locus_tag="ACL3R8_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1313954.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15833..16633
                     /locus_tag="ACL3R8_001067"
     CDS             15833..16633
                     /locus_tag="ACL3R8_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR1313955.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16644..17582
                     /locus_tag="ACL3R8_001068"
     CDS             16644..17582
                     /locus_tag="ACL3R8_001068"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR1313956.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEYAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17624..19525
                     /locus_tag="ACL3R8_001069"
     CDS             17624..19525
                     /locus_tag="ACL3R8_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGR1313957.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19586..21241)
                     /gene="pavA"
                     /locus_tag="ACL3R8_001070"
     CDS             complement(19586..21241)
                     /gene="pavA"
                     /locus_tag="ACL3R8_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR1313958.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKITSMKKS"
     gene            21346..21843
                     /gene="ybeY"
                     /locus_tag="ACL3R8_001071"
     CDS             21346..21843
                     /gene="ybeY"
                     /locus_tag="ACL3R8_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR1313959.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            21824..22219
                     /locus_tag="ACL3R8_001072"
     CDS             21824..22219
                     /locus_tag="ACL3R8_001072"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR1313960.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22236..23135
                     /gene="era"
                     /locus_tag="ACL3R8_001073"
     CDS             22236..23135
                     /gene="era"
                     /locus_tag="ACL3R8_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR1313961.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23184..24008
                     /gene="mutM"
                     /locus_tag="ACL3R8_001074"
     CDS             23184..24008
                     /gene="mutM"
                     /locus_tag="ACL3R8_001074"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR1313962.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24008..24613
                     /gene="coaE"
                     /locus_tag="ACL3R8_001075"
     CDS             24008..24613
                     /gene="coaE"
                     /locus_tag="ACL3R8_001075"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR1313963.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPFLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24600..25799
                     /locus_tag="ACL3R8_001076"
     CDS             24600..25799
                     /locus_tag="ACL3R8_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGR1313964.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRIFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            25799..25948
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001077"
     CDS             25799..25948
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1313965.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            25988..26221
                     /gene="secG"
                     /locus_tag="ACL3R8_001078"
     CDS             25988..26221
                     /gene="secG"
                     /locus_tag="ACL3R8_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR1313966.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26323..28677
                     /gene="rnr"
                     /locus_tag="ACL3R8_001079"
     CDS             26323..28677
                     /gene="rnr"
                     /locus_tag="ACL3R8_001079"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR1313967.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQTLGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDTVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28640..29107
                     /gene="smpB"
                     /locus_tag="ACL3R8_001080"
     CDS             28640..29107
                     /gene="smpB"
                     /locus_tag="ACL3R8_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR1313968.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29123..29983
                     /gene="tehB"
                     /locus_tag="ACL3R8_001081"
     CDS             29123..29983
                     /gene="tehB"
                     /locus_tag="ACL3R8_001081"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR1313969.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30056..31009
                     /gene="coiA"
                     /locus_tag="ACL3R8_001082"
     CDS             30056..31009
                     /gene="coiA"
                     /locus_tag="ACL3R8_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR1313970.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31028..32830
                     /gene="pepF"
                     /locus_tag="ACL3R8_001083"
     CDS             31028..32830
                     /gene="pepF"
                     /locus_tag="ACL3R8_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR1313971.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            32832..33545
                     /locus_tag="ACL3R8_001084"
     CDS             32832..33545
                     /locus_tag="ACL3R8_001084"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR1313972.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            33612..34553
                     /gene="prsA"
                     /locus_tag="ACL3R8_001085"
     CDS             33612..34553
                     /gene="prsA"
                     /locus_tag="ACL3R8_001085"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR1313973.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34672..35013)
                     /locus_tag="ACL3R8_001086"
                     /pseudo
     CDS             complement(34672..35013)
                     /locus_tag="ACL3R8_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            35427..35522
                     /locus_tag="ACL3R8_001087"
                     /pseudo
     CDS             35427..35522
                     /locus_tag="ACL3R8_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(35775..36395)
                     /locus_tag="ACL3R8_001088"
     CDS             complement(35775..36395)
                     /locus_tag="ACL3R8_001088"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1313974.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(36395..36877)
                     /locus_tag="ACL3R8_001089"
     CDS             complement(36395..36877)
                     /locus_tag="ACL3R8_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR1313975.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(36877..37719)
                     /locus_tag="ACL3R8_001090"
     CDS             complement(36877..37719)
                     /locus_tag="ACL3R8_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR1313976.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(37814..38614)
                     /locus_tag="ACL3R8_001091"
     CDS             complement(37814..38614)
                     /locus_tag="ACL3R8_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR1313977.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            38758..40137
                     /gene="glmU"
                     /locus_tag="ACL3R8_001092"
     CDS             38758..40137
                     /gene="glmU"
                     /locus_tag="ACL3R8_001092"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR1313978.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            40147..40692
                     /locus_tag="ACL3R8_001093"
     CDS             40147..40692
                     /locus_tag="ACL3R8_001093"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1313979.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            40704..41018
                     /gene="macP"
                     /locus_tag="ACL3R8_001094"
     CDS             40704..41018
                     /gene="macP"
                     /locus_tag="ACL3R8_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR1313980.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            41035..41727
                     /locus_tag="ACL3R8_001095"
     CDS             41035..41727
                     /locus_tag="ACL3R8_001095"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR1313981.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            41804..42295
                     /gene="rocS"
                     /locus_tag="ACL3R8_001096"
     CDS             41804..42295
                     /gene="rocS"
                     /locus_tag="ACL3R8_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR1313982.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            42393..42983
                     /locus_tag="ACL3R8_001097"
     CDS             42393..42983
                     /locus_tag="ACL3R8_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR1313983.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            42992..44755
                     /locus_tag="ACL3R8_001098"
     CDS             42992..44755
                     /locus_tag="ACL3R8_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR1313984.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        13594 a         8204 c         9986 g        13135 t
ORIGIN      
        1 tattggaaag taagaaatat tgaagctgag gctattagaa gaaattgtga gcgtggtgct
       61 attttttcag gtaaaataaa atatcacgaa gattcacagt ttaaaggaga tcactatgtt
      121 gaatgttatg ctgttttaga taatacggtt atagcaagag atagaataac agtccctatc
      181 gatccgttat gtggaaaaga ttttatagag tagcatataa ttgattctta actggaatac
      241 tcactatctc tttacatcaa gaaaatgact aaacagggaa gtttgccttc ttcccttttt
      301 ttgttatact agtagaagaa aaaatagaaa gatttgtggg agtgaaaaag tcctgtggac
      361 tttttcagcc tgagccaaga aactcgaaag cttgtaagtc tgattggctt tttcaatgtg
      421 aatcttaact tcacactccc aaagaggtat tagtgtcgtg tctcaatctt atatcaatgt
      481 tatcggtgct ggtttggcag gttctgaagc agcttaccaa atcgcagagc gtggtattcc
      541 agttaaacta tatgaaatgc gtggtgtcaa gtctacaccc cagcataaaa cagacaattt
      601 tgctgagttg gtttgttcca attctttgcg tggggatgct ttgacaaatg cagttggtct
      661 tctcaaggaa gaaatgcgtc gcttgggttc tgttatcttg gaatctgctg aggctacacg
      721 tgttcctgcc ggtggagccc ttgcggtgga tcgtgatggt ttctctcaaa tggtgaccga
      781 aaaagtggtc aaccacccct tgattgaagt ggtgcgtgat gaaattacag aattgccaac
      841 agatgttatt acagttgtgg cgactggtcc cttgactagc gatgccctgg ctgaaaagat
      901 tcatgccctt aataatggcg atggcttcta tttctacgat gcagcagcgc ctattatcga
      961 tgtcaacact atcgatatga gtaaggtcta tctcaaatct cgttatgata agggagaagc
     1021 agcctatctc aatgctccaa tgaccaagca agagtttatg gatttccatg aagccttggt
     1081 caatgcggaa gaagcaccgc tcaattcttt tgaaaaagaa aagtactttg aaggatgtat
     1141 gccaatcgaa gttatggcca aacgtggcat taaaactatg ctttatggcc ctatgaagcc
     1201 agtcggtctt gagtatccgg acgactacac aggacctcgt gatggagaat ttaaaacacc
     1261 ttatgcggtt gtgcaacttc gtcaggataa tgcagctggt agcctataca atattgttgg
     1321 tttccagacc cacctcaaat ggggagaaca aaagcgtgtc ttccaaatga ttccgggtct
     1381 tgaaaatgcg gagtttgtcc gttatggtgt catgcatcgc aattcttaca tggattcacc
     1441 aaatcttctt gagcagactt accgttccaa gaaacaacca aatctcttct ttgctggtca
     1501 gatgacgggg gtggaaggct atgttgagtc ggcggcttcg ggcttagttg cgggaattaa
     1561 cgcagctcgt ctcttcaagg aagaaagcga ggttattttc cccgagacga cagcgattgg
     1621 aagcttagct cattacatta cccatgccga cagcaaacat ttccaaccaa tgaatgtcaa
     1681 ttttgggatc atcaaggagt tggaaggcga gcgtatccgt gataagaagg ctcgttatga
     1741 aaaaattgca gagcgtgccc ttgccgactt agaggaattt ttgactgtct aatttttttg
     1801 aaagaattgt tcatgatact ataaaaatct tagaaattgt gataaaatag gtaggatgaa
     1861 agaaggagag tgaaaatggc gaatcccaag tataaacgta ttttaatcaa gttatcaggt
     1921 gaagcccttg ccggtgaacg tggcgtaggg attgatatcc aaacagttca aacaatcgca
     1981 aaagagattc aagaagttca tagcttaggt atcgaaattg cccttgttat cggtggagga
     2041 aatctctggc gtggagaacc tgcagcagaa gcaggtatgg accgtgttca ggcagattac
     2101 actggaatgc ttgggactgt tatgaatgct cttgtgatgg cagattcatt gcaacaagtt
     2161 ggggttgata cgcgtgtaca aacagctatt gctatgcaac aagtggcaga gccttatgtc
     2221 cgtggacgtg cccttcgtca ccttgaaaaa ggccgtatcg ttatctttgg tgctggaatt
     2281 ggttcaccat acttctcgac agatacaaca gcggcccttc gtgcagctga aatcgaagca
     2341 gatgccatcc tcatggctaa aaatggcgtc gatggtgtgt acaatgccga tcctaagaag
     2401 gacaagacag ccgttaagtt tgaagaattg acccaccgtg atgttatcaa caaaggtctt
     2461 cgtatcatgg actcaacagc ctcaaccctc tcaatggaca acgacattga cttggttgtc
     2521 ttcaacatga accaatcagg caacatcaaa cgtgtcgtat ttggtgaaaa tatcggaaca
     2581 acagtttcaa ataatatcga agaaaaggaa taagaaagaa tatggctaac gtaattattg
     2641 aaaaagctaa agagagaatg acccaatctc accaatcact tgctcgtgaa tttggtggta
     2701 tccgtgctgg tcgtgccaat gcaagcttgc ttgaccgtgt acatgtagaa tactatggag
     2761 tcgaaactcc tcttaaccaa atcgcttcaa ttacgattcc agaagcgcgt gttttgttgg
     2821 taacaccatt tgacaagtct tcattgaaag acatcgaacg tgccttgaac gcttctgatc
     2881 ttggtatcac accggctaat gacggttctg tgattcgctt ggttatccca gctcttacag
     2941 aagaaactcg tcgtgacctt gctaaagaag tgaagaaggt cggcgaaaat gctaaagtgg
     3001 ctgtccgcaa tatccgtcgc gatgctatgg acgaagctaa gaaacaagaa aaagcaaaag
     3061 aaatcactga agacgaattg aagactcttg aaaaagatat tcaaaaagta acagacgatg
     3121 ctgttaaaca catcgacgac atgactgcta acaaagagaa agaacttttg gaagtctaaa
     3181 aataaacaga aaaactcagt tggcattgct ggctgagttt tattcgaaag aaggaaatat
     3241 gaatacaaat cttgcaagtt ttatcgttgg actgatcatc gatgaaaatg accgttttta
     3301 ctttgtgcaa aaggatggtc aaacctatgc tcttgctaag gaagaaggtc aacatacagt
     3361 aggggatacg gtcaaaggtt ttgcatacac ggatatgaag caaaaactcc gcctgacaac
     3421 cttagaagtg actgccactc aggaccaatt tggttgggga cgtgtcacag aggttcgtaa
     3481 ggatttgggt gtctttgtgg atacaggcct tcctgacaag gaaatcgttg tgtcactcga
     3541 tattctccct gagctcaagg aactctggcc taagaagggc gaccaactct acatccgtct
     3601 tgaagtggat aagaaagacc gtatctgggg cctcttggct tatcaagaag acttccaacg
     3661 tcttgctcgt cctgcctaca acaacatgca gaaccaaaac tggccagcca ttgtttaccg
     3721 tctcaagctg tcaggaactt ttgtttacct accagaaaat aatatgcttg gttttattca
     3781 tcctagcgag cgttacgcag agccacgttt ggggcaagta ttagatgcgc gcgttattgg
     3841 tttccgtgaa gtggaccgca ctctgaacct ctccctcaaa ccacgctcct ttgaaatgtt
     3901 ggaaaacgat gctcagatga ttttgactta tttggaaagt aatggcggtt tcatgacctt
     3961 aaatgataag tcatctccag acgacatcaa ggcaaccttt ggcatttcta aaggtcagtt
     4021 caagaaagct ttaggtggtc ttatgaaggc tggtaaaatc aagcaggacc agtttgggac
     4081 agagttgatt tagggaggct tatgagaaaa tcattttaca cttggctcat gaccgagcgc
     4141 aatcctaaaa gtaacagtcc caaagcaatt ttggcagacc tcgcttttga agaggcagct
     4201 tttccaaaac atacagatga ttttgatgag gtcagtcgct ttttggagga gcatgccagt
     4261 ttctctttta acctaggaga ttttgacagc atttggcagg aatatctaga acactagcat
     4321 ttattcattg ggtttgggct agtaatttct ccatccctct gctataataa aaagaaataa
     4381 aaggattaga gaggttcttt atttgaagga acattcaata gacattcaac tgagtcatcc
     4441 agatgacctg tttcatcttt ttggttccaa tgaacgccat cttcgtttga tggaagaaga
     4501 gcttgatgtt gtgattcatg ctcgtacgga gattgtccag gttttgggag aagagtctgc
     4561 ctgtgaggaa gcccgtcaag ttattcaggc tttgatggtc ttggtaaatc gtgggatgac
     4621 cgttggtacg ccagatgtag tcactgcgat tagcatggtc aaaaatgatg aaattgacaa
     4681 gtttgtcgcc ctttacgaag aagaaattat caaagataat actgggaaac ctatccgtgt
     4741 caaaacccta gggcaaaagc tttatgtgga cagtgtcaaa cagcatgatg tgacctttgg
     4801 aattgggcca gcaggtacag ggaagacctt ccttgcagtg accttggcag tgactgccct
     4861 taaacgtggg caagtcaagc gaattatcct aactcgtcca gcggtggaag cgggagagag
     4921 tcttggattt cttccgggtg atcttaagga gaaggtggat ccttaccttc gtcctgttta
     4981 cgatgccttg tatcaaattc ttgggaaaga ccaaacgact cgtctcatgg agcgtgaaat
     5041 tatcgaaatt gcgccccttg cctatatgcg tggccggacc ttggatgatg cctttgtcat
     5101 tctcgatgag gcgcaaaaca cgaccatcat gcagatgaag atgttcttga cgcgtttagg
     5161 ctttcattct aagatgattg tcaatggaga tatcagtcag attgacctgc cacgtaatgt
     5221 caagtccggt ttgattgatg ctcaagagaa actcaagaac atccatcaga ttgactttgt
     5281 tcatttttca gccaaggatg tggttcgcca tccagttgtc gctcagatta tccgagccta
     5341 tgaatattct actgaagttg cacacgactg attttgagga agttcgcctg caaaagaata
     5401 tacttttgag agaggaaaat ccagttgtat aggctaaagg ttttatccaa aggtctgaga
     5461 caacgattag gcacgatgga aagaactttt atgtggctga tgacgatcag tgcatcttcc
     5521 tgtgtcataa tcacagggca caagaaagta ggaatttgaa aagatgattg accaactatc
     5581 taagtattac agttgtagga tactaactga aaaggatatt ccaagtattt tatctttata
     5641 tgaaagtaat cctctgtatt ttcagcattg tccaccagag ccaaattttg caactgtaaa
     5701 agaggacatg ctttgtctac ctgaaggtaa agctaaggct gataagtttt ttgttggatt
     5761 ttggaatgga tctgaccttg tggctgttat ggattttgtc tatgcctatc ctgatgagga
     5821 gactgttttt attggtttgt ttatggttga tcaagcctat cagaggaaag ggattggtag
     5881 tcatattgtg acagaagcac tagcttattt tgctaagaac tttcgaaagg cacgtttggc
     5941 ttatgttaag ggaaatccgc aatctcagca tttttgggaa aagcagggtt ttaaatcaat
     6001 tggatgcgag gttaagcaag aactctatac ggttgttatc gctgaacaga gcctagaaga
     6061 ttagaaatgg catcaagtaa gaactatttg gaatttgttt tggaacaatt atcaggatta
     6121 gatgatgtga cttaccgttc catgatgggg gagtatattc tttacttccg cggcaagatt
     6181 attggcggca tttatgatga tcgcttttta gttaaacccg tgcaagcagt cttagataag
     6241 attgaccaat cttcttttga gtttccatac aaaggtgcca aagaaatgat ttgagtggaa
     6301 gaacttgata ataagatgtt tctataagac ctgattttag ctatgtataa ccaactgcca
     6361 acgcccaaac ctaaaaagaa aaagcaaggg tgaacgaagt aaaaaagaag tctgctaagg
     6421 ccctgtcttt gcacgggtaa aattttatat ataaaaagaa gctgggacta aagagctcag
     6481 cttcctttgg tttatataat tgtcattaca agacgaagtg gttgggcgaa actctgttga
     6541 ctttattcaa tttagagttt cttatgcaca attgagtctg gaacgaaagt ctccagttgc
     6601 aaagtataca gtacaataaa ccaacgatgt aatagctgat gacacaaagc acagtgggta
     6661 ggacttgcga agtcaccctt ttcttttcaa aatttatact aaatcattga tatcagtgta
     6721 gtcacgatta agtccttgag caactggtag gctagtcaag taaccttgat aagtggtcac
     6781 accttgacgc aagccttcat cttcagagat tgcttgtgcg aatcctttgc cagccaaagc
     6841 ttcgatataa ggaagagtga cattggttag ggcgatggtt gaagtgcggg caaccgcacc
     6901 agggatattg gcaacggcat agtggagaac accgtgtttt tcatagacgg gttcatcgtg
     6961 cgttgtcaca cggtcagctg tttcgataac gccaccttgg tcaacagcaa cgtcaacgat
     7021 acagagcctg gacgcatttg tttgaccatc tcatctgtca ccaattccgg tgcttttgca
     7081 ccagggatga gaatggctcc aatcaccaca tcagcatctc tcacacttgc ttcaatgttg
     7141 aatgaattag acataagagt ttgaatttga cttccaaaga cttcttctag aactgagaga
     7201 cgcttggcac taatatctaa aatagtcact tgagcaccaa gaccaagggc gatgcgggca
     7261 gcatgtgtac cgacgacacc accaccgatg atagttactt ttccttttgg aacacctggt
     7321 acaccaccaa gtagaacacc agagccacca gcttgcttag taaggaagtg agctccgatt
     7381 taaacagcca tacgacctgc aacctcactc ataggaacga ggagcggtag ttgtccttga
     7441 ttgtcacgaa cagtttcata ggcaattcct gttgtttttg ctgctaacat agcatctgct
     7501 aattctggag cagcggccat gtgcaagtag gtgaagagaa gaagatcgtc gcgcaagtaa
     7561 ccgtattcag aacttaaagg ttcttttact ttcacaacca actctgctgc ccaagcttca
     7621 ccagcagtag cgacaatctc agctccttgc ttttgatagt cagcatcagt aaagccagaa
     7681 ccgagaccag catttgtttc gataaggaca cgatgaccac gactaactaa gctatgaaca
     7741 cctgcaggtg tgagggcgac acagttttcg ttatttttaa tttcttttgg gattccgatt
     7801 aacattgaga taacctacct ttcaattgac ggtcttgttt tggttgtcac attccagttc
     7861 ataaatcaaa aatgtgacgg tttcattgta tatgaaaccg cttcaaaaat caagaaaaac
     7921 ttgtcatcca aattttttat gctagactag tgaaaatcaa gctttgattg gttggaaaag
     7981 tatggaatca atttttgtaa aacttgccca gtatccgtct atagaaacgg agcgtttatt
     8041 gcttagacct gtaactttgg atgatgcgga agcaatgttt gactatgcct cggacaaggg
     8101 taatacacgt tacacttttc caaccaatca aagcttggaa gaaaccaaga ataacattgc
     8161 tcagttctat ttggctaatc ccttgggacg ttggggaata gaactaaaaa gcaatggtca
     8221 gtttattgga accattgact tgcacaagat tgattctgtt cttaagaagg cagctattgg
     8281 ctacattatc aataaaaagt attggaatca aggattaacg acagaagcca atcgtgctgt
     8341 gattgagcta gcttttgaga agatagggat gaataagttg actgcccttc acgataagga
     8401 caatcctgcg tcaggaaagg tcatggagaa atcaggcatg cgtttttccc atgcagaacc
     8461 atatgcttgt atggaccagc atgaaaaagg ccgaatcgtg acaagagttc attatgtctt
     8521 gaccaaggaa gactattttg caaataaata agcagttgaa aagaaatttt tcgactgttt
     8581 tttcttcctc ttacgaataa tctaagagag gagaaaatat ggaagcaatt atcgagaaaa
     8641 tcaaagagta taaaatcatc gtcatctgta ctggtctggg cttgcttgta ggcggatttt
     8701 tcctgctaaa gccagctcca caaacacctg taaaggaaac gaatttgcag gctgaagttg
     8761 cagctgtttc caaggatttg gtatccgaaa aggaagtgaa caaggaagag aaggaagaac
     8821 cccttgaaca agatctaatc acagtagatg tcaaaggtgc tgtcaaatcg ccagggattt
     8881 atgacttgcc tgtaggtagt cgagtcaatg atgctgttca gaaggctggt ggcttgacag
     8941 agcaagcaga cagcaagtcg ctcaatctag ctcagaaagt tagtgatgag gctctggttt
     9001 acgttcctac taagggagaa gaagcagtta gtcaacagac tggttcgggg acagcttctt
     9061 caacaagcaa ggaaaagaag gtcaatctca acaaggccag tctggaagag cttaaacagg
     9121 ttaagggact gggaggaaaa cgagctcagg acattataga ccatcgtgag gcaaatggga
     9181 aattcaagtc gattgatgaa ctcaagaagg tctctggcat tggtgctaag accatagaaa
     9241 agctaaaaga ctatgttaca gtggattaag aacatcccca ttcccctaat ttacctgagt
     9301 tttttgttac tttggtttta ttacgctatt ttctcagcat cctatcttgc tttgttgggc
     9361 tttgtttttc tgctagtctg tctctttttc caatttcctt ggaaatctgc tagcaaagtt
     9421 ctagtgattt gtggaatctt tggattttgg tttgtttttc aaaattggca acagagtcaa
     9481 gcgagtcaaa atctggcgga ttctgttgaa ggggtacgga ttttgcctga tactattaag
     9541 gttaatggtg atagtctatc ctttcgtggc aagtctaacg gtcgtgcttt ccaagtctat
     9601 tataaactcc agtccgagga ggagaaagaa gcctttcaag ctttaaccga cctgcatgag
     9661 ataggactag aagggaagct ttcggagcca gaagggcaga gaaattttgg tggctttaat
     9721 taccaagcct atctgaagac tcagggaatt taccagactc tcaatatcaa aacaatccag
     9781 tcacttcaaa agattggcag ttgggatata ggagaaaact tgtccagttt acgtcgaaag
     9841 gctgtggttt ggattaagac gcactttcca gaccctatgc gcaattacat gacaggactc
     9901 ttgctgggac atctggacac cgactttgag gagatgaatg agctttattc cagtctagga
     9961 attatccacc tctttgccct atctggcatg caggtaggtt ttttcatgaa tggatttaag
    10021 aaacttctct tgcgattggg cttgacccaa gaaaagttga aatggctgac ttatcccttt
    10081 tcccttatct atgcgggact aactggattt tcagcatcgg ttattcgcag tctcttgcaa
    10141 aagctactgg ctcaacatgg ggttaagggc ttggataatt ttgccttgac ggtgcttgtc
    10201 ctctttattg tcatgccaaa ctttttcttg acagcaggag gagtcttgtc ctgcgcttat
    10261 gcttttatcc tgaccatgac cagcaaagaa ggggaggggc tcaaggctgt tactagtgaa
    10321 agtctagtca tctccttggg catattgccc attctatcct tctattttgc ggaatttcaa
    10381 ccttggtcta tccttttgac ctttgtcttt tcctttctat ttgacttgac cttcttaccg
    10441 ctcttgtcta ttttatttgt cctttccttt ctctatccag tcattcagct gaactttatc
    10501 tttgaatggt tagagggcat tattcgcttg gtctcgcagg tggcaaggag accgcttgtc
    10561 tttggtcaac ccaacgcatg gcttttaatc ttattgttaa tttccttggc tttggtctat
    10621 gatttgagga aaaacattaa aggattaaca gtattgagtt tattgattac aggtctcttt
    10681 ttccttatca agtatccact ggaaaatgaa atcaccatgc tggatgtggg gcaaggagaa
    10741 agtattttcc tacgggatgt aactgggaaa accattctca tagatgtagg tggtaaggca
    10801 gaatcttata agaaaatcga aaaatggcaa gaaaagatga cgaccagcaa tgcacagaga
    10861 agcttgatac cctatcttaa aagtcgagga gtagctaaga ttgaccagct gattttgaca
    10921 aatacggaca aggaacatgt cggagatttg ttagaggtga ccaaggcttt ccatgtaggg
    10981 gagattttag tatcaaaagg cagtttgaag cagaagcaat ttgtggtaga actacaggcg
    11041 actcaaacaa aggtgcgtag tatgacagta ggggagaact tgcccatttt tggaagtcag
    11101 ttagaagttc tatctctaag gaaaatggga gatggaggac acgatgatac cctagttctg
    11161 tatgggaaat tcttggataa gcaatttctc ttcacgggaa atttggagga gaaaggagag
    11221 aaggacttgc tgaagcacta tccagacttg aaagtaaatg ttttgaaagc tagccaacat
    11281 ggcaataaaa aatcatcaag tccaaccttt ctagaaaaac tcaaaccaga gcttactctt
    11341 atctcagttg gaaagagcaa tcgaatgaaa ctcccccatc aggaaacatt gacacgactg
    11401 gaaggtatca atagcaaagt ttatcgaact gaccagcaag gagctatacg ttttaagggg
    11461 ttggatagtt ggaaaatcga aagtgttcga taggaaagat aaatgttgta gattagtgaa
    11521 ataaactaaa aatttgttgc ataataatga taaaaatggt ataatgaaaa cgtattcaat
    11581 attgaggata taaaatcatt aaaaatcagc aaaagttatt ttattagtta gtttataatc
    11641 tattggtctt cttcagtcca gtgtatctgc taagagtgtt cttaaaagta tcggtatgat
    11701 tggaatatct tctataagtc tagtatgaat ttccatggat atagacatac taacgttccg
    11761 tcatggtctc gttattacag ctattctgag tatccagttg gttctggctg gaactacggt
    11821 cgttatgaga tcataaacta ttacagcgga ggctattaat tcttaaagag tgagaaaaag
    11881 gagggctaga tatgttgcag cttactcatg tgaccttaaa aacgcgacaa gtcatcttgc
    11941 aagatgcgga tttcaccttt aaaaagggta ggttttatgg tcttcttgct atcaatggct
    12001 ctggaaagac gaccctgttc cgtgccatta gcaatttaat tcccataagt agtggaaata
    12061 tcgcagctcc tccttcttta ttttattatg agagtattga atggctggat ggaaacttaa
    12121 gtgggatgga ctaccttcgt cttatcaaaa acatctggaa gtcagaccta aacttgagag
    12181 atgaaatcgc ctactgggaa atggctgact atatcagtct tcccatccgc aagtattcct
    12241 taggcatgaa gcaacgcttg gtgattgcta tgtattttct cagtcaggcc aaatgctggc
    12301 tcatggatga gattacaaat ggcttagatg agtattatcg acagaagttt tttgataggt
    12361 tagcacaaat cgatagacaa gaacagctgg ttcttttaag ttcccactat aaggaagagt
    12421 tggttgatat ctgcgataga gtagtaacca ttcatcaggg gcagatagaa gaggtttagt
    12481 ttatgaaaga tgttagtcta tttttattga aaaaagtttt caaaagccgc ttaaactgga
    12541 ttatcttagc tttatttgta tctgtactcg gtgttacttt ttattttaat agtcagactg
    12601 caaactcagt cagcttggag agagagttgg aaactcgtct tgtagaccgt gagagagtca
    12661 tcaatgaata tgaagagaaa ctctcccaaa tgtctgatac cagctcggag gaataccagt
    12721 ttgctaaaaa taatttagac gtgcaaaaaa atcttttgac gcgaaagaca gaaattctaa
    12781 ctttactaaa agaagggcgc tggaaagagg cctactatct gcagtggcaa gatgaagaga
    12841 aagattatga atttgtatca aatgacccga ctgctagctc tgaattaaaa atgggggttg
    12901 accgcgaacg gaagatttat caagccctgt atcccttgaa cataaaagca catactttgg
    12961 agtttccgac ccacgggatt gatcagattg tctggatttt agaggctatc atcccaacct
    13021 tatttgtgat tggtattatt tttatgctaa cacaactatt tgcagaaaga tatcaaaatc
    13081 atctggacac agctcactta tatcctgttt caaaagtgac atttgcaata tcctctcttg
    13141 gagttggagt gggatatgta actgtgctgt ttatcggaat ctgtggcttt tcttttctag
    13201 tgggaagtct gataagtggt tttggacagt tagattatcc ctactcaatt tatagcttag
    13261 tgaatcaaga agtaactatt gggaaaatac aagatgtatt atttcctggc tcactcttag
    13321 ctttcttagc ctttatcgtc attgtggaag ttgtgtactt gattgcttat tttttcaagc
    13381 aaaaaatgcc tgtcctcttt ctttcactca ttgggattgt tggcttattg tttggcatcc
    13441 aaacaattca gcctcttcaa aggattgcac atctgattcc ctttacttac ttgcgttcag
    13501 tggagatttt atctggaaga ttatctaagc agattgataa tgtcgatcta aattggagca
    13561 tggggatggt cttacttcct tgcctgatta tccttttgtt agtggggatt ctatttatcg
    13621 aaagctgggg aagttcacgt aaaaaggaag tttttaaagt ttagttttcc tatagggaag
    13681 ctaaagaaaa actaacatag ggagagaatc aacttggttc tctctttttg attcgaaaac
    13741 caaaccaaaa tacaaacaca aacttttcaa aaaataactt tttatcttga caagagctag
    13801 aaaacttggt atcatataaa agttgagaaa agcagaagtg agagcttctc gccttgtgac
    13861 attaagttgc ctggccctac ggatgaaaag tttcgaagaa acgctatcat aacgtgcggg
    13921 cttgtatatt tacgagtccg ctattgtttt tctctaataa aacaaaagag gtgaaaacca
    13981 tagcaaagca agacttattc atcaatgatg agattcgtgt acgtgaagtt cgcttgattg
    14041 gtcttgaggg agaacagcta ggcatcaagc cactcagtga agcgcaagct ttggctgata
    14101 acgctaatgt tgacctagta ttgattcaac cccaagccaa accgcctgtt gcaaaaatta
    14161 tggactacgg taagttcaaa tttgagtacc agaagaagca aaaagaacaa cgtaaaaaac
    14221 aaagcgttgt tactgtgaaa gaagttcgtc taagtccaac aattgacaag ggtgactttg
    14281 atacaaaact tcgtaatgca cgtaagttcc ttgaaaaagg aaataaagtt aaggtatcta
    14341 ttcgctttaa gggtcgtatg attacccata aagagattgg tgcaaaagtt ttagccgagt
    14401 ttgctgaagc aactcaagat attgccatca tcgaacaacg tgctaaaatg gatggacgtc
    14461 aaatgttcat gcaattggcg ccagcgactg acaaaaaata attgtcagaa agttaaataa
    14521 aggagaaaaa atcatgccaa aacaaaaaac acaccgcgca tcagctaaac gtttcaaacg
    14581 tacaggttct ggtggactta aacgtttccg tgcttacact tctcaccgtt tccacggaaa
    14641 aactaagaaa caacgtcgtc atcttcgtaa agcatctatg gtgcattcag gagattacaa
    14701 acgtatcaaa gcaatgctta ctcgcttgaa ataatagctt gactgtaagt aaacaattct
    14761 aggaaatatt tggaggaaat aaaacatggc acgtgttaaa ggtggcgttg tatcacgcaa
    14821 acgtcgtaaa cgtattctta aattagcaaa aggttactat ggagctaaac acatcttgtt
    14881 ccgtactgca aaagaacaag taatgaactc ttactactat gcataccgtg accgtcgtca
    14941 gaaaaaacgt gacttccgca aattgtggat cactcgtatc aatgcggcag ctcgtatgaa
    15001 cggactttca tactcacaat tgatgcatgg tttgaaattg gctgagatcg aagttaaccg
    15061 taaaatgctt gctgacttgg ctgttaacga tgcagtagct ttcacagctc ttgcagatgc
    15121 agctaaagca aaacttggta aataacaact gatgagactg gaacaggatt gtccagtctt
    15181 tttaaaaata aaggagaaag atatggcttc aaaaatgcta cacacttgct tacgagtaga
    15241 aaatcttgaa aaatcaatcg cattttatca agatgctttt ggttttaaag aattgcgtcg
    15301 cagagatttt ccagaccatg ccttcacgat tgtctatcta ggtcttgagg gtgatgatta
    15361 tgagttggag ttgacttata actacgatca cggtccgtat gtggttggtg atgggtttgc
    15421 ccatatcgcc ctcagtacac ctgatcttga ggcacttcat caagaacaca gtgcaaaagg
    15481 ctatgaagtg actgagccaa atggtctacc aggaactaca ccaaactatt actttgttaa
    15541 agaccctgat ggatataagg tcgaagtcat tcgtgaaaaa taatttcgtg caagttaagt
    15601 agaatattcg ttttctactt gacttttttt agctgaaaga gtatactaat aaaaattcaa
    15661 cctttaaggg gagtccagag agactcacaa ggtgtcagat aaaagaatag tgcaattttc
    15721 tagaggagac cttttgagtg tgctctcttg tgttgtacga ttttaactga ggccttgcac
    15781 tagcaaggtc ttttctttat ctggtcccct taaaatttaa ggaggaaaag ttatgaatct
    15841 cacatgtaag aagcgtttgg gtgtcattcg gttggaaacc atgaaggtgg ttgcacaaga
    15901 ggaaatcgcg ccagcaatct ttgaattagt cctagaagga gaaatggttg aagccatgcg
    15961 agcaggccaa tttcttcatc tgcgtgtacc agacgatgcc catctcttac gtcgtcctat
    16021 ttcaatttcg tctattgaca aggcaaacaa gcagtgtcac ctcatttatc ggattgaggg
    16081 agctgggact gcaatttttt caaccttaag tcagggagac actcttgatg tgatggggcc
    16141 tcagggaaat ggttttgact tgtctgacct tgatgagcag aatcaggttc tccttgttgg
    16201 tggtgggatt ggtgttccac ccttgcttga ggtggccaag gaattgcatg aacgtggagt
    16261 gaaagtagtg acagtcctcg gttttgctaa taaggatgct gttattttga aaacggaatt
    16321 ggctcagtat ggtcaggtct ttgtaacgac agatgatggt tcttatggca tcaagggaaa
    16381 tgtttccgtt gttatcaatg atttagatag tcagtttgat gctgtttact cgtgtggggc
    16441 tccaggaatg atgaagtata tcaatcaaac ctttgatgat cacccaagag cctatttatc
    16501 tctggaatct cgtatggctt gtgggatggg agcttgctat gcctgtgttc taaaagtacc
    16561 agaaagcgag acggtcagcc aacgcgtctg tgaagatggt cctgttttcc gcacaggaac
    16621 agttgtatta taaggagaaa attatgacta caaatcgatt acaagtgtct ctacctggtt
    16681 tggatttgaa aaatccgatt attccagcat caggctgttt tggctttgga caagagtatg
    16741 ccaagtacta tgatttagac cttttaggtt ctattatgat caaggcgaca acccttgaac
    16801 cacgttttgg gaatccaact ccaagagtgg cagagacgcc tgctggtatg ctcaatgcaa
    16861 ttggcttgca aaatcctggt ttagaggttg ttttggctga aaagctacct tggctggaaa
    16921 gagaatatcc aaatcttcct attattgcca atgtagctgg tttttcaaaa caagagtatg
    16981 cagctgtttc tcatgggatt tccaaggcaa ctaatgtaaa agctatcgag ctcaatattt
    17041 cttgtcccaa tgttgaccac tgtaatcatg gacttttgat tggtcaagat ccagatttgg
    17101 cttatgatgt ggtgaaagca gctgtggaag cctcagaagt gccagtttat gtcaaattaa
    17161 ccccgagtgt gaccgatatc gttactgtcg caaaagctgc agaatatgcg ggagcaagtg
    17221 gcttgaccat gatcaatact ctggttggaa tgcgctttga cctcaaaacc agaaaaccaa
    17281 tcttggccaa tggaacaggt ggaatgtcag gtccagcagt ctttccagta gccctcaaac
    17341 tcatccgcca agtagcccaa acaacagacc tgcctatcat tggaatgggg ggagtggatt
    17401 cggctgaagc tgccctagaa atgtatctgg ctggggcatc tgctatcgga gttggaacag
    17461 ctaactttac caatccttat gcctgccctg acatcatcga aaatttacca aaagtcatgg
    17521 ataaatacgg tattagcagt ctggaagaac tccgtcagga agtaaaagag tctctgaggt
    17581 aaactgcaat caatctgttc ttgatttttt attagtttgt aatatgaatt taggagaatt
    17641 ttggtacaat aaaataaata agaacagagg aagaaggtta atgaagaaag taagatttat
    17701 ttttttagct ctgctatttt tcttagctag tccagagggt gcaatggcta gtgatggtac
    17761 ttggcaagga aaacagtatc tgaaagaaga tggcagtcaa gcagcaaatg agtgggtttt
    17821 tgatactcat tatcaatctt ggttctatat aaaagcagat gctaactatg ctgaaaatga
    17881 atggctaaag caaggtgacg actattttta cctcaaatct ggtggctata tggccaaatc
    17941 agaatgggta gaagacaagg gagcctttta ttatcttgac caagatggaa agatgaaaag
    18001 aaatgcttgg gtaggaactt cctatgttgg tgcaacaggt gccaaagtaa tagaagactg
    18061 ggtctatgat tctcaatacg atgcttggtt ttatatcaaa gcagatggac agcacgcaga
    18121 gaaagaatgg ctccaaatta aagggaagga ctattatttc aaatccggtg gttatctact
    18181 gacaagtcag tggattaatc aagcttatgt gaatgctagt ggtgccaaag tacagcaagg
    18241 ttggcttttt gacaaacaat accaatcttg gttttacatc aaagaaaatg gaaactatgc
    18301 tgataaagaa tggattttcg agaatggtca ctattattat ctaaaatccg gtggctacat
    18361 ggcagccaat gaatggattt gggataagga atcttggttt tatctcaaat ttgatgggaa
    18421 aatggctgaa aaagaatggg tctacgattc tcatagtcaa gcttggtact acttcaaatc
    18481 cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt tttacctcaa
    18541 atctgatggg aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcctggta
    18601 ctacttcaaa tctggtggct acatggcgaa aaatgagaca gtagatggtt atcagcttgg
    18661 aagcgatggt aaatggcttg gaggaaaaac tacaaatgaa aatgctgctt actatcaagt
    18721 agtgcctgtt acagccaatg tttatgattc agatggtgaa aagctttcct atatatcgca
    18781 aggtagtgtc gtatggctag ataaggatag aaaaagtgat gacaagcgct tggctattac
    18841 tatttctggt ttgtcaggct atatgaaaac agaagattta caagcgctag atgctagtaa
    18901 ggactttatc ccttattatg agagtgatgg ccaccgtttt tatcactatg tggctcagaa
    18961 tgctagtatc ccagtagctt ctcatctttc tgatatggaa gtaggcaaga aatattattc
    19021 ggcagatggc ctgcattttg atggttttaa gcttgagaat cccttccttt tcaaagattt
    19081 aacagaggct acaaactaca gtgctgaaga attggataag gtatttagtt tgctaaacat
    19141 taacaatagc cttttggaga acaagggcgc tacttttaag gaagccgaag aacattacca
    19201 tatcaatgct ctttatctcc ttgcccatag tgccctagaa agtaactggg gaagaagtaa
    19261 aattgccaaa gataagaata atttctttgg cattacagcc tatgatacga ccccttacct
    19321 ttctgctaag acatttgatg atgtggataa gggaatttta ggtgcaacca agtggattaa
    19381 ggaaaattat atcgataggg gaagaacttt ccttggaaac aaggcttctg gtatgaatgt
    19441 ggaatatgct tcagaccctt attggggcga aaaaattgct agtgtgatga tgaaaatcaa
    19501 tgagaagcta ggtggcaaag attagtacta taagtgaata tgatttgagt gaatagtaag
    19561 ttaaaaatcc tgatttcaag taaaatcagg attttttcat ggatgtaatt tttttggagt
    19621 ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt tttccaccag
    19681 ttggtttatt gagttttttg acttcaatca tatctacctg caccagattc gacaggcgcc
    19741 cttgagagaa gtaggcagct aactctgctg cgtctgtctt gactgcatca gatgggtcaa
    19801 gatttcctga gatgacaaca tggcttccag gaatgtcctt agcatggaac caaagttcct
    19861 ccttgcgggc cattttaaag gtcaattcct cattttgaag attgtttcgt ccgacataga
    19921 tgatggtttt gccatcgctt gctagatatt gttctagttt tttgcgtttc tggattttct
    19981 cccgttgtct tctgcggata aaacctgttt gaatcaattc ttcacggatt tcagcgattt
    20041 cttccagtcc agcttggttg aggacggttt ctacactttc cagatagaga atagtggctt
    20101 tggtttcttc aatcaaatca gtcaagtatt tgacagcttc tttgagtttc tgataccgtt
    20161 taaaatagcg ttgggcattc tggttgggag tcagagcctt atcaagcgca atcatgatag
    20221 gttggttggt atagtagttg tctaggataa cctggtcttg gtcgttaggc acttggtgga
    20281 ggaaggttgt cagcaattct cctttttgac gaaattcttc agcgttgtct gtcgccagta
    20341 attctttttc ctgttttttg agtttgtgtc ggtttttctg aagttcattt tcaacacgac
    20401 gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc agccttatcc ttatagtagg
    20461 tgtccaacaa atcagaaaga tttgcaaaag gctctcccac ctgatttgca aaaggaactg
    20521 gactgaagga agtctcagtc aagcatggct tggtttcctg attgaaaaaa tttcggaaag
    20581 cggaaagttt ttcactaacc agtatccttt ccaattcatt tgccgtatcg cgtcccagac
    20641 cttgaaagag gctttgaaga ttttttgctg ttagttcttg ggtttgcagg atttcaaaga
    20701 gcttttcatc cttgatagta aaaggattga gagattctgt acttggcgga gcgatatagg
    20761 tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa gccgacgtgt ttgataactt
    20821 cgaggatttt atgactgctt ttatcgacca gtagaatatt actgtgtttc cccataattt
    20881 cgataatcaa ggtagcctgg atatggtctc caatctcgtt tttattggaa actgtcattt
    20941 ccacaatacg gtcattttcc acttgctcaa tcgactcaat cagggccccc tgcaaatact
    21001 ttctcaaaac catgataaag gtagaaggtt gggctggatt ttcaaaagtc gtttgggtca
    21061 gctgaatgcg tccaaaaact ggatgggcag aaaggagcag gcgatggctt tggcgattgc
    21121 tgcggatttg caagaccaac tcttgttcaa aaggctgatt gattttctgg atgcgaccat
    21181 tcactaattc gcttcgcaat tcctcaacta tgtggtgtaa aaaaaatccg tcaaatgaca
    21241 tcgttctctc cttgtgattg tattccatag tattatatca aaaaggtaga ataaaatcat
    21301 ggaaatgtgg tataataaag ccaagtaaag agaaacgaga agcacatgta tattgaaatg
    21361 gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga aattttggaa
    21421 tttgcagcca aaaaattagg aaaagaagac aaggagatgg cagtcacttt tgtgaccaat
    21481 gagcgtagtc atgaacttaa tctggagtac cgtgacaccg accgtccgac agatgtcatc
    21541 agccttgagt ataaaccaga attggaaatt gcctttgacg aagaggattt gcttgaaaat
    21601 ccagaattgg cagagatgat gtctgagttt gatgcctata ttggggaatt gttcatctct
    21661 atcgataagg ctcatgagca ggccgaagaa tatggtcaca gctttgagcg tgagatgggc
    21721 ttcttggcag tacacggctt tttacatatt aacggctatg atcactatac tccggaagaa
    21781 gaagcggaga tgttcggttt acaagaagaa attttgacag cctatggact cacaagacaa
    21841 taaacgaaaa tggaaaaatc gtgacctgat atccagttta gaatttgcca tcacagggat
    21901 ttttactgct atcaaggaag aacgcaatat gcgaaaacat gcagtgacgg ctctagtggt
    21961 catccttgca ggttttggtt ttcaggtgtc acgaatcgaa tggctctttc tcctattgag
    22021 cattttcttg gtggtagcct ttgaaattat caattctgct attgaaaatg tggtggattt
    22081 ggccagtcac tatcactttt ccatgctggc taaaaatgcc aaggatatgg cggctggcgc
    22141 ggtattagtg gtttctcttt ttgcagcctt aacaggcgca ttgatttttc tcccacgaat
    22201 ctgggattta ttattttaaa cagtaagagg aaattatgac ttttaaatca ggctttgtag
    22261 ccattttagg acgtcccaat gttgggaagt caaccttttt aaatcacgtt atggggcaaa
    22321 agattgccat catgagtgac aaggcgcaga caacgcgcaa taaaatcatg ggaatttaca
    22381 cgactgataa ggagcaaatt gtctttatcg acacaccagg gattcacaaa cctaaaacag
    22441 ctctcggaga tttcatggtt gagtctgcct acagtaccct tcgcgaagtg gacactgttc
    22501 ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt atcgagcgtc
    22561 tcaaggctgc caaggttcct gtgattttgg tggtgaataa aatcgataag gtccatccag
    22621 accagctctt gtctcagatt gatgacttcc gtaatcaaat ggactttaag gaaattgttc
    22681 caatctcagc ccttcaggga aataacgtgt ctcgtctagt ggatattttg agtgaaaatc
    22741 tggatgaagg tttccaatat ttcccgtctg atcaaatcac agaccatcca gaacgtttct
    22801 tggtttcaga aatggttcgc gagaaagtct tgcacttaac tcgtgaagag attccgcatt
    22861 ctgtagcagt agttgttgac tctatgaaac gagacgaaga gacagacaag gttcacatcc
    22921 gtgcaaccat catggtcgag cgcgatagcc aaaaagggat tatcatcggt aaaggtggcg
    22981 ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat cgaactcatg ctaggagaca
    23041 aggtcttcct agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa aagctagatt
    23101 tggctgactt tggctataat gaaagagaat actaagtaga ggtaggctca tgcctgcttc
    23161 ttgtttttac agaaggagga cttatgcctg aattacctga ggttgaaacc gtttgtcgtg
    23221 gcttagaaaa attgattata ggaaagaaga tttcgagtat agaaattcgc taccccaaga
    23281 tgattaagac ggatttggaa gagtttcaaa gggaattgcc tagtcagatt atcgagtcaa
    23341 tgggacgtcg tggaaaatat ttgctttttt atctgacaga caaggtcttg atttcccatt
    23401 tgcggatgga gggcaagtat ttttactatc cagaccaagg acctgaacgc aagcatgccc
    23461 atgttttctt tcattttgaa gatggtggca cgcttgttta tgaggatgtt cgcaagtttg
    23521 gaaccatgga actcttggtg cctgaccttt tagacgccta ctttatttct aaaaaattag
    23581 gtcctgaacc aagcgaacaa gactttgatt tacaggtctt tcaatctgcc cttgccaagt
    23641 ccaaaaagcc tatcaaatcc catctcctag accagacctt ggtagctgga cttgggaata
    23701 tctatgtgga tgaggttctc tggcgagctc aggttcatcc agctagacct tcccagactt
    23761 tgacagcaga agaagcgact gccattcatg accagaccat tgctgttttg ggccaggctg
    23821 ttgaaaaagg tggctccacc attcggactt ataccaatgc ctttggggaa gatggaagca
    23881 tgcaggactt tcatcaggtc tatgataaga ctggtcaaga atgtgtacgc tgtggtacca
    23941 tcattgagaa aattcaacta ggtggacgtg gaacccactt ttgtccaaac tgtcaaagga
    24001 gggactgatg ggaaaaatca tcggaatcac tgggggaatt gcctcaggta agtcaactgt
    24061 gacaaatttt ctaagacagc aaggctttca agcagtggat gccgacgcag tcgtccacca
    24121 actacagaaa cctggtggtc gtctgtttga ggctctagta cagcactttg ggcaagaaat
    24181 cattcttgaa aacggagaac tcaatcgccc tttcctagct agtctcatct tttcaaatcc
    24241 tgaagagcaa aaatggtcta atcaaattca aggggagatt atccgtgagg aactggctac
    24301 tttgagagaa cagttggctc agacagaaga gattttcttc atggatattc ccctactttt
    24361 tgagcaggac tacagcgatt ggtttgctga gacttggttg gtctatgtgg accgagatgc
    24421 ccaagtagaa cgcttaatga aaagggacca gttgtccaaa gatgaagctg agtctcgtct
    24481 ggcagcccag tggcctttag aaaaaaagaa agatttggcc agccaggttc ttgataataa
    24541 tggcaatcag aaccagcttc ttaatcaagt gcatatcctt cttgagggag gtaggcaaga
    24601 tgacagagat taactggaag gataatctgc gtattgcctg gtttggtaat tttctgacag
    24661 gagccagtat ttctttggtt gtacctttta tgcccatctt cgtggaaaat ctaggtgtag
    24721 ggagtcagca agtcgctttt tatgcaggct tagcaatttc tgtctctgct atttccgcgg
    24781 cgctcttttc tcctatttgg ggtattcttg ctgacaaata cggccgaaaa cccatgatga
    24841 ttcgggcagg tcttgctatg actatcacta tgggaggctt ggcctttgtc ccaaatatct
    24901 attggttaat ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt cctaatgcaa
    24961 cggcactgat agccagtcag gttccaaagg agaaatcagg ctctgcctta ggtactttgt
    25021 ctacaggcgt agttgcaggt actctaaccg gtccctttat tggtggcttt atcgcagaat
    25081 tatttggcat tcgtacagtt ttcttactgg ttggtagttt tctattttta gctgctattt
    25141 tgactatttg ctttatcaag gaagattttc aaccagtagc caaggaaaag gctattccaa
    25201 caaaggaatt atttacctcg gttaaatatc cctatctttt gctcaatctc tttttaacca
    25261 gttttgtcat ccaattttca gctcaatcga tcggccctat tttggctctt tatgtacgcg
    25321 acttagggca gacagagaat cttctttttg tctctggttt gattgtgtcc agtatgggct
    25381 tttccagtat gatgagtgca ggagtcatgg gcaagctagg tgacaaggtg ggcaatcatc
    25441 gtctcttggt tgtcgcccag ttttattcag tcatcatcta tctcctctgt gccaatgcct
    25501 ctagccccct tcaactagga ctctatcgtt tcctctttgg cttgggaacc ggtgccttga
    25561 ttcccggggt taatgcccta ctcagcaaaa tgactcccaa agccggcatt tcgaggatct
    25621 ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt tggtcccatg gcaggttctg
    25681 cagtagcagg tcaatttggc taccatgctg tcttttatgc gacaagcctt tgtgttgcct
    25741 ttagttgtct ctttaacctg attcaatttc gaacattatt aaaagtaaag gaaatctagt
    25801 gcgagtaaaa attaatctca aatgctcctc ttgtgacagt atcaattacc taaccagtaa
    25861 aaattcaaaa acccatccag acaagattga ggttttaaag tattgtccca aggaaagaaa
    25921 agtaacccta catcttgaat ctaagtagat tttatggtaa aataataggg attttaagga
    25981 gtttgatatg tataacctat tattaaccat tttattagta ttatctgttg tgattgtgat
    26041 tgcaattttc atgcaaccaa ccaaaaacca atccagcaat gtatttgatg ccagttcagg
    26101 tgatttgttt gaacgcagta aagctcgcgg ttttgaagct gtaatgcagc gtttgacagg
    26161 gattttagtc tttttctggc tagccattgc cttagcattg acggtattat caagtagata
    26221 agaaaataat gggcaggact aggtctttgc ctctttttat ttttaaagga tgtttgagaa
    26281 ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga tagaataaaa
    26341 gaatatttac aagacaaggg aaaggtgact gttaatgatt tggctcagac tttgggaaaa
    26401 gacagttcca aggattttcg tgagttgatt aaaaccttgt ccttaatgga aagaaagcac
    26461 cagattcgct ttgaagaaga tggtagtctg acattagaaa ttaagaaaaa acatgagatt
    26521 accctcaagg ggatttttca tgcccataaa aatggctttg gctttgttag tctggaaggc
    26581 gaggaggacg acctttttgt agggaaaaat gatgtcaact atgctattga tggtgatacc
    26641 gtcgaggtag tgattaagaa agtcgctgac cgcaataagg gaacagcagc agaagccaaa
    26701 attattgata tcctagaaca cagtttgaca acagttgtcg ggcaaatcgt tctggatcag
    26761 gaaaagccta agtatgctgg ctatattcgt tcaaaaaatc agaaaatcag tcaaccgatt
    26821 tatgttaaga aaccagccct aaagttagaa ggaacagaag ttctcaaggt ctttatcgat
    26881 aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt agtgggacac
    26941 tcaacggatg tcggaattga tgttcttgag gtcttggaat caatggacat tgtatccgag
    27001 tttccagaag ctgttgttaa ggaagcagaa agtgtgcctg atgctccgtc tcaaaaggat
    27061 atggaaggtc gtctggatct aagagatgaa attaccttta ccattgacgg tgcggatgcc
    27121 aaggacttgg acgatgcagt gcatatcaag gctctgaaaa atggcaatct ggagcttggg
    27181 gttcacatcg cagatgtttc ttattatgtg accgaggggt ctgcccttga caaggaagcc
    27241 cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct tccagaacga
    27301 ctatcaaatg gcatctgctc tctcaatccc caagttgacc gcctgaccca gtctgctatt
    27361 atggagattg ataaacatgg tcgtgtggtc aactatacca ttacacaaac agttatcaag
    27421 actagttttc gtatgaccta tagcgatgtc aatgatatcc tagctggcga tgaagaaaag
    27481 agaaaagaat atcataaaat tgtatcaagt atcgaactca tggccaagct tcatgaaact
    27541 ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg ataccaatga agcgaagatt
    27601 ttagtggata aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg tattgccgag
    27661 cggatgattg agtcttttat gttgatggct aatgaaacag ttgccgaaca tttcagcaag
    27721 ttggatttgc cttttatcta tcgaattcac gaggagccta aggctgaaaa ggttcagaag
    27781 tttattgatt atgcttcgag ttttggcttg cgcatttatg ggactgccag tgagattagt
    27841 caggaggcac ttcaagacat catgcgtgct gttgagggag aaccttatgc agatgtattg
    27901 tccatgatgc ttcttcgctc tatgcagcag gctcgttatt cggagcacaa tcacggccac
    27961 tatggactag ctgctgacta ttatactcac tttaccagtc caattcgtcg ttatccagac
    28021 cttcttgttc accgtatgat tcgggattac ggccgttcta aggaaatagc agagcatttt
    28081 gaacaagtga ttccagagat tgcgacccag tcttccaacc gtgaacgtcg tgccatagaa
    28141 gctgagcgtg aagttgaagc catgaaaaag gctgagtata tggaagaata cgtgggtgaa
    28201 gagtatgata cagttgtatc aagtattgtc aaattcggtc tctttgtcga attgccaaac
    28261 acagttgaag gcttgattca catcactaat ctacctgaat tttatcattt caatgagcgt
    28321 gatttgactc ttcgtggaga aaaatcaggt atcactttcc gagtgggtca gcagatccgt
    28381 atccgtgttg aaagagcgga taaaatgact ggagagattg atttttcatt cgtacctagt
    28441 gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc gtagtggcag agggcgtggt
    28501 tcaaatcgtc gttcggataa gaaggaagac aagagaaaat taggacgctc aaatgataag
    28561 cgtaagcatt cacaaaaaga caagaagaaa aaaggaaaga aaccttttta caaggaagta
    28621 gctaagaaag gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac aaaataaaaa
    28681 ggcacgccac gactatacaa tcgtagatac gctagaggca gggatggtcc tgactggaac
    28741 tgaaatcaag agtgtacgag ctgctcgaat taatctcaag gatggctttg ctcaagtgaa
    28801 aaatggagaa gtttggctga gcaatgttca tatcgcgcct tacgaagagg gcaatatctg
    28861 gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat aaaaagcaaa ttcaaaaatt
    28921 ggaacaagag accaaaggga caggaatgac cttagttccc cttaaggtct atataaaaga
    28981 tggctacgct aagcttcttt taggacttgc caaagggaag catgactatg acaaacggga
    29041 gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag ctgttaatca
    29101 gcgataaaaa gaggaattga aaatggaaaa attagttgcc tataaacgca tgcctttgtg
    29161 gaataaacaa acaatgcctg aagctgttca gcaaaagcac aatacaaaag ttgggacttg
    29221 ggggaaaatt actgtcttga agggagctct caagtttatt gaattgacag aagaagggga
    29281 agttctagct gaacacctct ttgaagcagg ggcagacaat ccaatggccc aacctcaagc
    29341 ctggcaccga gtggaagctg ccacagatga tgtggaatgg tacttggaat tttattgtaa
    29401 acctgaggat tattttgcta aaaaatacaa taccaatcct gttcattcag aggtcctaga
    29461 ggccatgcag acagtgaaac aagggaaagc tttggattta ggttgtggtc aggggcgtaa
    29521 ttctcttttt ctagcccagc aagattttga tgtgacagct gtagatcaaa atggactagc
    29581 tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg gacatgcctg ttggccttta
    29641 cgatatcaat tcagctagca ttgaacaaga atatgatttt atcgtttcaa cagttgttct
    29701 catgtttcta caagcggacc gcattccagc tattattcaa aatatgcagg agaaaaccag
    29761 tgttggtggt tacaacctta tcgtttgtgc catggacacg gaggattatc cttgctcggt
    29821 taacttccca ttcaccttta aagaaggaga actggcagac tattacaagg attgggaatt
    29881 ggttaagtac aatgaaaatc caggccattt gcatcgtcgc gatgagaatg gcaatcgtat
    29941 tcaactacgc tttgcgacct tactagctaa gaaaatcaag taaacacaca tgaagattag
    30001 gaattttcct gatctttttt cttttttacg aatgatatag aaaaggaggg aattcatgtt
    30061 tgttgcgaga gatgctaggg gagaattggt aaatgtgtta gaggataaac ttgagaagca
    30121 agcatacacc tgcccagctt gtggaggcca gctccatttg cgtcaaggac caagtgtacg
    30181 gacgcatttt gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa atgaaagtcc
    30241 agaacacctg gccaataagg aatccctcta tcactggttg aaaaaagaga caaaggttca
    30301 attagagtac ccgctttcag aacttaaaca gattgcggat gtatttgtaa atggcaatct
    30361 agctctagaa gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc gaagtgaggg
    30421 ctatcgtagt cagggttacc aagtactgtg gttgctgggt caaaaactgt ggctcaagga
    30481 gcgtttgact cgtctacagc aaggttttct ttatttcagt caaaacatgg gcttttatgt
    30541 ttgggaatta gacaaggaaa aacaagtttt aagactcaaa tacctgattt accaggatct
    30601 ccgcggtaaa ctccattatc aaatcaagga attttcctat ggtcaaggta gtttattgga
    30661 aatattgcgt cttccctata agagacaaaa aatatctcat tttacagttt ctgaggacaa
    30721 ggacatctgt cgctatatcc ggcaacaact ttattatcaa aatctctttt ggatgaaaga
    30781 acaagcagaa gcctatcaaa agggagaaaa tatcctgact tatggactga aagaatggta
    30841 tccacaaatt cgaccaatag tgggcaaatt tttccagatt gaacaagact tgactagcta
    30901 ttatcagcac ttttatacct attaccaaaa aaatcctcaa aatgattggc aaaagcttta
    30961 tccaccagcc ttttatcagc aatatttctt gaaaaatatg gtagaataga aaggatggag
    31021 gaatctaatg gtattacaaa gaaatgaaat aaatgaaaaa gatacatggg atctatcaac
    31081 gatctaccca actgaccagg cttgggaaga agccttaaaa gatttaacag aacaattgga
    31141 gacagtagcc cagtatgaag gccatctctt ggatagtgcg gataacctac tagaaatcac
    31201 tgaattttct cttgaaatgg aacgccagat ggagaagctt tacgtttatg ctcatatgaa
    31261 gaatgaccag gatacacgtg aagctaagta tcaagagtac tatgccaagg ccatgacact
    31321 ctacagccag ttagaccaag ccttttcatt ctatgagcct gaatttatgg agattagcga
    31381 aaagcagtat gctgactttt tagaagctca accaaagctg caggtttatc aacactattt
    31441 tgacaagctc ttgcaaggca aggatcacgt tctttcacaa cgtgaagaag aattattggc
    31501 tggagctgga gaaatctttg gttcagcaag tgaaaccttc gctatcttgg acaatgcgga
    31561 tattgtgttc ccttatgtcc tagacgatga tggtaaagaa gttcagctat ctcatgggac
    31621 ttacacacgt ttgatggagt ctaaaaaacg tgaggttcgc cgtggtgcct atcaagctct
    31681 ttatgcgact tacgaacaat tccaacacac ctatgccaaa actttgcaaa ccaatgttaa
    31741 ggtgcaaaat taccgtgcta aagttcgtaa ctacaagagt gctcgtcatg cagccctcgc
    31801 agcgaatttt gttccagaaa gtgtttatga caatttggta gcagcagttc gcaagcattt
    31861 gccactctta catcgctatc ttgagcttcg ttcaaaaatc ttggggattt cagatctcaa
    31921 gatgtacgat gtctacacac cgctttcatc tgttgaatac agttttacct accaagaagc
    31981 cttgaaaaaa gcagaagatg ctttggtagt cttgggtgag gattacttga gccgtgttaa
    32041 acgtgccttc agcgagcgtt ggattgatgt ttacgaaaat caaggcaagc gttcaggtgc
    32101 ctactctggt ggttcttacg ataccaatgc ctttatgctt ctcaactggc aggacaatct
    32161 ggacaatctc tttactcttg ttcatgaaac aggtcacagt atgcattcaa gctatactcg
    32221 tgaaactcag ccttatgttt acggagatta ctctatcttt ttggctgaga ttgcctcaac
    32281 taccaatgaa aatatcttga cggagaaatt attggaagaa gtggaagacg acgcaacacg
    32341 ctttgctatt ctcaataact tcctagatgg tttccgtgga acagttttcc gccaaactca
    32401 atttgctgag tttgaacacg ccattcacca agcagatcaa aatggggagg tcttgacaag
    32461 cgatttccta aataaactct acgcagactt gaaccaagag tattatggtt tgagtaagga
    32521 agacaatcct gaaatccaat acgagtgggc tcgcattcca cacttctact ataactacta
    32581 tgtatatcaa tattcaactg gctttgcggc cgcctcagcc ttggctgaaa aaattgtcca
    32641 tggtagtcaa gaagaccgtg accgctatat cgactacctc aaggcaggta agtcggacta
    32701 tccacttaat gtcatgagaa aagctggtgt tgatatggag aaggaagact acctcaacga
    32761 tgcctttgca gtctttgaac gccgtttaaa tgagtttgaa gcccttgttg aaaaattagg
    32821 attggcataa aatggttgaa tcgtatagta agaatgctaa ccataacatg cgtcgtcctg
    32881 tcgtcaaaga agaaattgta gacttgatgc gtcagcgtca aaagcaggtc acaggtttct
    32941 tgaaagaatt ggaagacttt gcccgcaagg aaaatattcc tattattccc catgaaacgg
    33001 ttgcttattt ccgttttctt atggaaacca tgcagcctaa aaatattctg gaaattggga
    33061 cggctatcgg tttttcagct ctcttgatgg ctgaacatgc gccaaatgct aagattacaa
    33121 ctattgatcg taatccagaa atgattggtt ttgccaagga aaattttgcc cagtttgaca
    33181 gtcgcaagca aatcactctc ctagagggag atgcggtgga tgtcttatct acactgacag
    33241 agtcttatga tttcgtcttt atggattctg ccaagtctaa atacatcgtc tttctgccag
    33301 aaatcctcaa acatttggaa gttggtggtg tggttgtctt ggatgatatt tttcaaggcg
    33361 gtgatgttgc caaggacatt atggaagtcc gtcgaggtca gcgaaccatc tatcgaggcc
    33421 ttcaaagact atttgacgca accttagaca attcagaact caccgcaaca ttagtgcctt
    33481 taggagatgg tattctcatg cttcgtaaaa atgtagcaga tgttcaattg cctgacagcg
    33541 aatgattttc agaaaaattt aagaaaaaat agtaaaatag atagagtaac acttatctca
    33601 aaggagtaga catgaagaaa aaattattgg caggtgccat cacactatta tcagtagcaa
    33661 ctttagcagc ttgttcgaaa gggtcagaag gagcagacct tatcagcatg aaaggggatg
    33721 tcatcacaga acatcaattt tatgagcaag tgaaaaacaa cccttcagcc caacaagtct
    33781 tgttaaatat gaccatccaa aaagtttttg aaaaacaata tggctcagag cttgatgata
    33841 aagaggttga tgatactatt gccgaagaaa aaaaacaata tggcgaaaac taccaacgtg
    33901 tcttgtcaca agcaggtatg actcttgaaa cacgtaaagc tcaaattcgt acaagtaaat
    33961 tagttgagtt ggcagttaag aaggtagcag aagctgaatt gacagatgaa gcctataaga
    34021 aagcctttga tgagtacact ccagatgtaa cggctcaaat catccgtctt aataatgaag
    34081 ataaggccaa agaagttctc gaaaaagcca aggcagaagg tgctgatttt gctcaattag
    34141 ccaaagataa ttcaactgat gaaaaaacaa aagaaaatgg tggagaaatt acctttgatt
    34201 ctgcttcaac agaagtacct gagcaagtca aaaaagccgc tttcgcttta gatgtggatg
    34261 gtgtttctga tgtgattaca gcaactggca cacaagccta cagtagccaa tattacattg
    34321 taaaactcac taagaaaaca gaaaaatcat ctaatattga tgactacaaa gaaaaattaa
    34381 aaactgttat cttgactcaa aaacaaaatg attcaacatt tgttcaaagc attatcggaa
    34441 aagaattgca agcagccaat atcaaggtta aggaccaagc cttccaaaat atctttaccc
    34501 aatatatcgg tggtggagat tcaagctcaa gcagtagtac atcaaacgaa tagtccaaat
    34561 caatgagtca gggaaaaaac tcgacttcag gaaaaaatga agcaaacatt cccacaataa
    34621 aacgcatagt acaaggtttg tactgccccc caaaaaagtt agacaattaa tttatccgaa
    34681 ggatttagtt ctgtattgca cagagctaag tccttttagt tttatcttaa ttctcttatt
    34741 gttgtaataa tcaatatagt ctataatggc ttgttccaat tgattaagtg atttaaatgt
    34801 ttgctcatag ccataaaaca tttcggattt taaaatgcca aagaaagatt ccatcctacc
    34861 gttgtcttgg ctgtttcctt tgcgtgacat agatgcttga attcccttac tctctaggaa
    34921 gcgatgataa gaatcgtgtt ggtattgcca gccttggtca ctatggagaa tcgtattctc
    34981 gtagtgcttc tctttgaatg cctgttccaa cattaacgat caatcaattt aatcatgtac
    35041 ctaatattag aattgtttat ctcaaattta tttgaaagtt tctctaagct atatccttgt
    35101 tttctaagtt catagatctg aactttatca tcataagtta atttcataat aaaaacaccc
    35161 caaaagttag attttttctg tctaactttt ggggggcagt tcatttaaca cctgataata
    35221 tgcgtttttt gattttaaag actttttgac cagtctcatt tttttaactt gatactcagt
    35281 gcaaagcaaa gattaaacta ggaagctagc tgtaggctgc tcaaagaaca gctttgaggt
    35341 tgtagataaa acttgtgagg tcaccaacat atataatgtg aagctgacgt ggtttgaata
    35401 gattttagaa gagtatgagt ctggaagttt taatggataa tgcaagattc catagaatgg
    35461 gtaagctaga gttcttatgt gaagagtttg ggcataaact tttacctttt cctccctact
    35521 catcttagta tagaaaagtg aatctgaaat agtacataac tgcttctaaa acattcttat
    35581 aaattgattt aaattctcaa atcatattat tcagttctta tttcattttg ttctacaatc
    35641 ctgttgagaa gacacgtgtt catatcaaaa aggtattggc aagttgcaat acctttttac
    35701 gaggctctgt tgtcttattt ttgtttcaac tgactatatc tcctatggtt ctagttcaga
    35761 aggctaggct ataattatga ttgataagaa gtatcattcc aagtattggg agtgaatgtt
    35821 tcaaaatcat gggtttctat aatggtcagg ctggcatttg ctagaccgcc atctttacga
    35881 agaagtggtt ctttatagcc taggagagta cgaagactgg cagtaagatt ggcgccgtgt
    35941 ccgacaatta gaatacgttc agctggacta tcttttaatg atttgataaa ttggatggtc
    36001 cgttgagttg tactatagag ggattcggct ccgaacattc gagtgtcaaa ttgagcaaga
    36061 tttgaacgaa aagcctggat ttgttgcggg taaatagctt ccaaggttgc aattttcaaa
    36121 ccttctaact tcccaagttg ccattcacgg agattaggaa cgatttctaa agaacagggg
    36181 gtatagagtt gactttggat aatctcagca gatttgaccg ctcgaggtaa atcacttgaa
    36241 taaatctgat caaaaggaat ttccttgaga tactgaccaa gtcgttttag ggtttcaatg
    36301 gattcaggaa gaagaggaga atcaccacta gcaccttgaa aacgaccttc ttggttccag
    36361 agggtacgac cgtggcggac aaagtagagt ttcattactt gatgtcctcc aaaatatcta
    36421 caaagtctgc ctttacaaag ctagccaagt cttgtggcgc gacgataatg ctgtgtccga
    36481 cttcgcctgc agagacaatc atttgatcca aatctagagc aattttatcg ataaaaatgg
    36541 gataattgtg tttctgacga attccgacag gattattggc tccatgaatg taaccagttg
    36601 ttttttctaa gtccttttgt ggaatcatgc tcactttttt attgccagaa attttagcta
    36661 gtttcttttc agacaagtgc tgagtgatag ggacaattcc gataatcggt ccggtcttgt
    36721 ctcccaaaag cgccaaggtt ttgaaaatct gatctcgttc ataaccttga ggaagctctc
    36781 cttctagggc attgatttga atcccctgat gagggatagc tgctttagat aggatttgtt
    36841 ccaccaatgt ttttttgatt ttaacttttt ttgccattat ttatatttat cctccaattg
    36901 actcatccaa ataccaagcc agattcccag cgcaaagaag aaggcgatga tgacataacc
    36961 gacaagtgaa agtcctgtgt attggatact ttcagcgttt cctgcatttg gaattaagat
    37021 caaaagggta cttgatagga cgataccgat gatgaaatga tagacgtgtg agtggtagtt
    37081 gtttaaggca taatccatca attttgaaaa aacgatgaga gttgcacctg caccaattcc
    37141 aatcggaaag aaggttccca agagatcaaa agttttaaaa ccagtcaaca taggagcata
    37201 gagtcccaaa atcaaaagta agttcgatgg gctgaggcca ggaaccaaga cgccaagggc
    37261 caatagtgcg cctgctagga cgaagttaag aaagctggcg cttaaggttc caacgacaaa
    37321 atttaaggca tagagtccta atccagaaat gataaaggtt gtccataacc aagctaaatc
    37381 aatcttgtct cggtcagatt ctcgagttga ttctttgagg aggctaggaa ctgtaccgat
    37441 aatagctccc gcaaagctcc ataatacaaa aacctgataa ttttcaagca ggtattcaat
    37501 cgggtaggaa aataagccga ttcccagaag cataccgatg gcaactggaa taaagtacaa
    37561 aacattttct ttaaagtctt taaagggatg ggccagaaag ccaatcattc gttcatagat
    37621 tcctaagatt gctgctagaa cccctccgga aattcccggt aggataaatc caagagcaat
    37681 tacaatccct ttaataacgc gtgctaacca tgagagcata tatttcctcc aactatttct
    37741 atttcaaaaa atccttacta tattgtatca caatcagaca caaaaagaaa aagcaaatga
    37801 taaacaaatg cttttaaggt tttaaaaaaa gttttcgaaa ggtttcttct ttatttttta
    37861 agggagagat aacgttgata tctaaatcgt ggtcaaagcc agcaattttt cctttagatg
    37921 tgtattggtg aatatcataa tctaaatcag ttttaggact gctctccaaa aatcctgagt
    37981 ctgagccgta ggacggaatc caaacagagg taaacttgcc tgtatcaata ctgtgttctt
    38041 ccatgaagta gacaccaacg tagatgccga tgtttttagc acctagtgat gctagttttg
    38101 ctcgaaagtt ttcgacacct tcgttcatat tagacatggt tttgtcttcc acgtcaagcc
    38161 aatagtaact agggctgtaa ggagaggcag cattgtagaa aacttcggca gccttttcca
    38221 tttcttggac actttttcca gctacataag cgtagacagc aactgggaca ttccgctttt
    38281 gaagttcagt gatatgactc ttataggcct tgtctattcc attgataaat gaagcatcat
    38341 tttcttttgt tgtttgagca ccactgtgaa cacgaacaat agcacctgaa atattttgtg
    38401 agagggcatc gtagttgatt tcctcaggac gctgccagcc agagaggtca ataatcggtt
    38461 tgtctaagtg tttcaaagcc tgtgcttcaa tctgtgctat attggatttt gttttaaacg
    38521 attggctgtc attaagtggg cgattgatga ttaaaatgaa catcataatc ccaaaaaaac
    38581 taaataaaat aagtggatga atttgttttc tcatatctta taattctacc ctaaaaatca
    38641 aaaaaaatca aaaaaatggg ttaaggaaga gactttagag cattttttca ttcaagagtg
    38701 cggaatgatt tgaaatatgg tataataaaa gggaatttct acagaaaaga gaagattatg
    38761 tcaaattttg ccattatttt agcagcgggt aaagggactc gcatgaaatc tgatttgcca
    38821 aaagttttgc acaaggttgc gggtatttct atgttggaac atgttttccg tagtgtggga
    38881 gctatccaac ctgaaaagac agtaacagtt gtaggacaca aggcagaatt ggttgaggag
    38941 gtcttggctg aacagacaga atttgtgact caatctgaac agttgggaac tggtcatgca
    39001 gttatgatga cagagcctat cttagaaggt ttgtcaggac acaccttggt cattgcagga
    39061 gatactcctt taatcactgg tgaaagcttg aaaaacttga ttgatttcca tatcaatcat
    39121 aaaaatgtgg ccactatctt gactgctgaa acggataatc cttttggcta tggacgaatt
    39181 gttcgtaatg acaatgctga ggttcttcgt attgttgagc agaaggatgc tacagatttt
    39241 gaaaagcaaa tcaaggaaat caacactgga acatacgtct ttgacaacga gcgtttgttt
    39301 gaggctttga aaaatatcaa taccaataac gctcaaggcg aatactatat tacagacgtc
    39361 attggtattt tccgtgaaac tggtgaaaaa gttggcgctt atactttgaa agattttgat
    39421 gaaagtcttg gggtaaatga ccgtgtggcg cttgcgacag ctgagtcagt tatgcgtcgt
    39481 cgcatcaatc ataaacacat ggtcaacggt gttagctttg tcaatccaga agcaacttat
    39541 atcgatattg atgttgagat tgctccggaa gttcaaatcg aagccaatgt tatcttgaaa
    39601 gggcaaacga aaattggtgc tgagactgtt ttgacaaacg gtacttatgt agtggacagc
    39661 actatcggag caggagcggt cattaccaat tctatgattg aggaaagtag tgttgcagac
    39721 ggtgtgacag tcggtcctta tgctcacatt cgtccaaatt caagtctggg tgcccaagtt
    39781 catattggta actttgttga ggtgaaagga tcttcaatcg gtgagaatac caaggctggt
    39841 catttgactt atatcggaaa ctgtgaagtg ggaagcaacg ttaatttcgg tgctggaact
    39901 attacagtca actatgacgg caaaaacaaa tacaagacag tcattggaaa caatgtcttt
    39961 gttggttcaa attcaaccat tattgcacca gtagaacttg gtgacaattc cctcgttggt
    40021 gctggttcaa ctattactaa agacgtgcca gcagatgcta ttgctattgg tcgcggtcgt
    40081 cagatcaata aagacgaata tgcaacacgt cttcctcatc atcctaagaa ccagtaggag
    40141 cctatcatgg agtttgaaga aaaaacgctt agcagaaaag aaatctatca aggaccaata
    40201 tttaaactgg tccaagatca ggttgaatta ccagaaggca agggaactgc ccaacgggat
    40261 ttgatttttc acaatggggc tgtctgtgtt ttagcagtaa cggatgaaca aaaacttatc
    40321 ttggtcaagc agtaccgcaa agctatcgag gcagtctctt acgaaattcc agccggaaaa
    40381 ttggaggtag gagaaaacac agcccctgtc gcagctgccc ttcgtgaatt agaggaagaa
    40441 acagcctata cagggaaatt agaactcttg tacgattttt attcagctat tggcttttgt
    40501 aatgagaagt taaaactata tttagcaagc gatttgacaa aagtggaaaa tccgcgtccg
    40561 caggatgagg atgaaacctt ggaagtcctt gaagtgagct tagaagaagc gaaagaatta
    40621 atccaatcag gtcatatctg tgatgccaag acaattatgg ctgttcagta ttgggagttg
    40681 cagaaaaaat agaggaggtc agtatgggta aatctttatt aacggatgaa atgattgaaa
    40741 gagctaatag aggcgaaaaa atttcaggtc ctcctttgct agatgataat gaggaaacta
    40801 agattttacc aacctcttct tcccgttttg gttatgccaa tcctaaggat catggtttta
    40861 gccaggaaac cttgaagatt caggtcgaac catctattca taaaagccgt cgtattgaaa
    40921 ataccaagag aaatgtcttc aattctaagt tgaataaaat cttattcgcg gtcatctttc
    40981 tcttgatttt gcttgtttta gcaatgaaac ttttgtaata gaaaaggaat tgaaatgaaa
    41041 ataggaatta ttgctgctat gccagaagaa ctggcttatc tggtccagca tttagacaat
    41101 gcccaggagc aagttgtttt ggggaatacc tatcatacag gaaccattgc ttctcatgaa
    41161 gtcgttcttg tagaaagtgg aattggtaag gtcatgtctg ctatgagtgt ggcgattttg
    41221 gctgatcatt tccaggtgga tgcccttatt aatacgggtt cagctggggc agtagcagaa
    41281 ggtatcgctg ttggggatgt cgtgattgct gacaaattag cctatcatga cgtggatgtc
    41341 acagcttttg gctatgctta tggacaaatg gcgcaacaac cgctttattt cgaatcagac
    41401 aaaacctttg ttgctcaaat ccaagagagt ttatctcaat tggaccaaaa ctggcatctt
    41461 ggtttgattg ctacaggaga tagttttgtt gcaggaaatg acaagataga agcgattaag
    41521 tcccatttcc cagaagtttt agccgtggag atggaggggg cagctattgc tcaagcagcg
    41581 catgccctca atctcccagt cttagtcatc agagctatga gtgacaatgc caaccatgaa
    41641 gcaaacatct tttttgatga gtttattatc gaagctggac gtcgctctgc ccaagtcttg
    41701 ttgacctttt tgaaggcttt agattaagtg gaaatttgac agtttttcta gcttatgata
    41761 agatttaagt aaagaaaagc tagaaaacgt ttcagaggat attatgagta ttgaaatgac
    41821 cgtcagtgag attgcagagg tcttaggatt atctcgccaa gcaatcaata accgtgtcaa
    41881 agaattacca gaagaagaca cagataaaaa tgacaaaggg gtaacagttg ttaccagaag
    41941 tggcttgatt aagctagaag aaatctataa aaaaacgatt tttgaagatg aacctgtcag
    42001 tgaagatgtc aaacaacgtg aactgatgga gattctagtg gatgagaaga atgcagaaat
    42061 tcttcgtctt tatgaacaat taaaagccaa ggatcgtcag ttatcagaaa aagacgagca
    42121 gatgcgtatc aaagaccgtc agattgctga gaaagacaaa caattagatc agcaacaaca
    42181 attgaccctt caagccatga aggatcaaga aaatcttaag ctagagctgg accaagcaaa
    42241 agaagaagtc caatccacta aaaaaggctt ttttgctcgt ttatttggag gataatcaag
    42301 gagctgttta ggttaaatgc taacctgatg gcttcttttg tttgtgaata gtatagttga
    42361 ttagaacaga gacagtagag gagaggtaca gaatggaacg attagaagat tacattgctt
    42421 ttgatttaga atttaatcag catgaaggac aaacacactt gattcaagta tcggcagtgc
    42481 gttttagaga tggtcgggaa atcgatgcct atgattccta tgttcatacc agcgtccctc
    42541 taaaaagctt tatcaatggt ttgaccggga ttacagctga gaccttaaaa gatgctcctc
    42601 cagttgagaa agtcttagaa gaattccaag agtttgtggg ttctttgctg atgataggct
    42661 acaatgctgc taaaagtgat ttacctattt tagcagagca tggtttagac tatagccaac
    42721 agtacaaggt ggatttgtat gatgaagctt ttgaacgtcg gagttcagat ttacatggta
    42781 ttgccaatct caaattgcaa actgttgcct catttcttgg atttcaaggt cagtctcata
    42841 atagtttaga ggatgctcgg atgacggcgc gtgtttacga atccttctta gagtcggatc
    42901 aagctaggga attgttagag acagaaagta gcttatcaaa caatcctttt ggtggcttgg
    42961 acttgtctca attatttgac taggagtgcc tatgaaacct gaaaaaccta aaaaattggg
    43021 tcttaaacag atttacctca atcttgataa aatcctcttt ctatttttct tgatttttat
    43081 gatagtggag tatttgtggg taccattcaa ttcatggttg gctagcttct tattagatca
    43141 gacaggttat ctttttattt cctataacaa tgtcttagcc atccttactc attctccatt
    43201 gattagtcta gcttttttag ccttgattgt aattaacttt ctggttgctt attttcaaat
    43261 aggactcctc tttattggtg ctcgtcatct cctctataat gaaaagcgaa ggctaattga
    43321 gtatatccgc aaggttttcc atgaaagttt tgaatttatg aaaaagctaa ctggcgctaa
    43381 agccttgttt atctttttct atatagctat gctgtttcct tttatacgga aaatgctgaa
    43441 gatttattat cttaataaaa tcgtcattcc agagtttatc caagcttatt tagaagataa
    43501 atattggatg tggtggctga gcatcctact tctatctctt atctttctct atgtctctgt
    43561 cagattgatg tttgcccttc cgaagattgt atatgatcag ctgactgttc gagaagcagt
    43621 gatgtttagc ttggagaaaa ccaagaagag agttactttt tatgcttgga atttatttta
    43681 catcttgctc aaagcacatt tattatttta tcttcctttg attcctttat tattggctca
    43741 aactttggta gatgatatca ctcagagaga gtctctgatt cttggtattt tgaattttgt
    43801 tgtgattaaa aatctctatt atatggctct gacttatttt ttggttaaat ttgtttcatt
    43861 tttgacagga aaggagctgg atatgcttcc taggagagaa aaagatcaca tcgtgcgatg
    43921 gggtgtcatg acttgtgcca gtcttttctt tgccttagaa ggttatattt atctggaggc
    43981 tcccatggtt catctacctc aacttatttc tcaccgaggg gtttccaatg caaatgggat
    44041 tcaaaataca gtagagtcct tggaaactac agcacaactc aaaccagact tggtggagac
    44101 ggacgtgcag gaaacaaaag atgggcagtt tgtcatgatg catgatgcta acttgaaaaa
    44161 tctagcaggt atcaataaaa gtcctcaaga cttaaacttg gaggagctta aagggattga
    44221 tatttttgaa aatggctacc agactaaaat ttcaagcttt gaagattatc tcagtcgagc
    44281 caacgaactt ggtcaaaaat tactaattga aattaaaacc agtaaaaaag atagtccaga
    44341 catgatggac cgctttttag cccgttatgc tgcaaagctc aagatttatg gacatcaaat
    44401 ccagtcttta gactaccatg ttgtcgaaaa agtaagacag tatgatgccg aactgccagt
    44461 ttatttcatc atgccctaca attctgtctt tcctaaaaca agagcgacag gatatactat
    44521 ggagtactca accttggatg aatattttgt aagcaaacta tggacaacgg atcagaaact
    44581 ttatgtctgg actgtcaatg attcagaagc tatcagcaaa tctcttcact taggagtaga
    44641 tggagtgatt acagatgatt tggaaaaagt tcagcgggaa atagaagtag cccaagaaga
    44701 tccagaatat acggatttgc tcttgaaaaa agcattggaa ttctttgaat tttagtaata
    44761 aaaaagagga acggttgttc ctcccatgat aggtaagtat tcttgtgaat gcttgctttt
    44821 ttgtggttgc aatccgttta cgagaattgt ttgtattgtt cttgtttcaa tttactttat
    44881 agtgctttga agttggaatg ctacactata acttctaaa
//
LOCUS       DBEJZJ010000016        43198 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000016 DBEJZJ010000000
VERSION     DBEJZJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 43198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.16"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            5..92
                     /locus_tag="ACL3R8_001099"
     tRNA            5..92
                     /locus_tag="ACL3R8_001099"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Ser,seq:gct)
     gene            complement(218..1153)
                     /gene="birA"
                     /locus_tag="ACL3R8_001100"
     CDS             complement(218..1153)
                     /gene="birA"
                     /locus_tag="ACL3R8_001100"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR1313985.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1150..2010)
                     /locus_tag="ACL3R8_001101"
     CDS             complement(1150..2010)
                     /locus_tag="ACL3R8_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR1313986.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHMGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2118..4280
                     /locus_tag="ACL3R8_001102"
     CDS             2118..4280
                     /locus_tag="ACL3R8_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR1313987.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQIEKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            4315..5573
                     /locus_tag="ACL3R8_001103"
                     /pseudo
     CDS             4315..5573
                     /locus_tag="ACL3R8_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            5587..6453
                     /locus_tag="ACL3R8_001104"
     CDS             5587..6453
                     /locus_tag="ACL3R8_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313988.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIVMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6467..7300
                     /locus_tag="ACL3R8_001105"
     CDS             6467..7300
                     /locus_tag="ACL3R8_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR1313989.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7611..9053
                     /gene="gtfA"
                     /locus_tag="ACL3R8_001106"
     CDS             7611..9053
                     /gene="gtfA"
                     /locus_tag="ACL3R8_001106"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR1313990.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9191..10384
                     /locus_tag="ACL3R8_001107"
     CDS             9191..10384
                     /locus_tag="ACL3R8_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR1313991.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11070..13049
                     /locus_tag="ACL3R8_001108"
     CDS             11070..13049
                     /locus_tag="ACL3R8_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1313992.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13116..14612
                     /locus_tag="ACL3R8_001109"
     CDS             13116..14612
                     /locus_tag="ACL3R8_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1313993.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14612..15538
                     /gene="oppC"
                     /locus_tag="ACL3R8_001110"
     CDS             14612..15538
                     /gene="oppC"
                     /locus_tag="ACL3R8_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR1313994.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15547..16614
                     /locus_tag="ACL3R8_001111"
     CDS             15547..16614
                     /locus_tag="ACL3R8_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313995.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYAPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16625..17551
                     /locus_tag="ACL3R8_001112"
     CDS             16625..17551
                     /locus_tag="ACL3R8_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1313996.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18042..18979
                     /locus_tag="ACL3R8_001113"
                     /pseudo
     CDS             18042..18979
                     /locus_tag="ACL3R8_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            18991..19868
                     /locus_tag="ACL3R8_001114"
                     /pseudo
     CDS             18991..19868
                     /locus_tag="ACL3R8_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            19881..20684
                     /locus_tag="ACL3R8_001115"
     CDS             19881..20684
                     /locus_tag="ACL3R8_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1313997.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20717..21427)
                     /gene="treR"
                     /locus_tag="ACL3R8_001116"
     CDS             complement(20717..21427)
                     /gene="treR"
                     /locus_tag="ACL3R8_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR1313998.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYIVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21612..23579
                     /gene="treP"
                     /locus_tag="ACL3R8_001117"
     CDS             21612..23579
                     /gene="treP"
                     /locus_tag="ACL3R8_001117"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR1313999.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQVQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23757..25382
                     /gene="treC"
                     /locus_tag="ACL3R8_001118"
     CDS             23757..25382
                     /gene="treC"
                     /locus_tag="ACL3R8_001118"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR1314000.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25638..25886
                     /locus_tag="ACL3R8_001119"
     CDS             25638..25886
                     /locus_tag="ACL3R8_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR1314001.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26093..26887
                     /gene="racE"
                     /locus_tag="ACL3R8_001120"
     CDS             26093..26887
                     /gene="racE"
                     /locus_tag="ACL3R8_001120"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR1314002.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26884..27855
                     /locus_tag="ACL3R8_001121"
     CDS             26884..27855
                     /locus_tag="ACL3R8_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR1314003.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27831..28352
                     /locus_tag="ACL3R8_001122"
     CDS             27831..28352
                     /locus_tag="ACL3R8_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR1314004.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28349..28810
                     /gene="cbpB"
                     /locus_tag="ACL3R8_001123"
     CDS             28349..28810
                     /gene="cbpB"
                     /locus_tag="ACL3R8_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR1314005.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28807..29541
                     /gene="xerD"
                     /locus_tag="ACL3R8_001124"
     CDS             28807..29541
                     /gene="xerD"
                     /locus_tag="ACL3R8_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR1314006.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29541..30269
                     /locus_tag="ACL3R8_001125"
     CDS             29541..30269
                     /locus_tag="ACL3R8_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR1314007.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30288..30857
                     /gene="scpB"
                     /locus_tag="ACL3R8_001126"
     CDS             30288..30857
                     /gene="scpB"
                     /locus_tag="ACL3R8_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR1314008.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30844..31566
                     /locus_tag="ACL3R8_001127"
     CDS             30844..31566
                     /locus_tag="ACL3R8_001127"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR1314009.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31566..31808
                     /gene="yidD"
                     /locus_tag="ACL3R8_001128"
     CDS             31566..31808
                     /gene="yidD"
                     /locus_tag="ACL3R8_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR1314010.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32033..32998)
                     /locus_tag="ACL3R8_001129"
     CDS             complement(32033..32998)
                     /locus_tag="ACL3R8_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1314011.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIIGMPTKTIPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSIKANIES
                     LASAFGETSIQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33094..33846)
                     /locus_tag="ACL3R8_001130"
     CDS             complement(33094..33846)
                     /locus_tag="ACL3R8_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314012.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33843..34799)
                     /locus_tag="ACL3R8_001131"
     CDS             complement(33843..34799)
                     /locus_tag="ACL3R8_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR1314013.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(34789..35748)
                     /locus_tag="ACL3R8_001132"
     CDS             complement(34789..35748)
                     /locus_tag="ACL3R8_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314014.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36045..36155)
                     /locus_tag="ACL3R8_001133"
     CDS             complement(36045..36155)
                     /locus_tag="ACL3R8_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR1314015.1"
                     /translation="MNYLFQEDSSSQIFNLETKKGYTIKEIFKTAEELLN"
     gene            complement(36171..36872)
                     /locus_tag="ACL3R8_001134"
     CDS             complement(36171..36872)
                     /locus_tag="ACL3R8_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGR1314016.1"
                     /translation="MTKTILVTGETGYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKSYLEENQIDAALHCAGETVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37142..38512
                     /locus_tag="ACL3R8_001135"
     CDS             37142..38512
                     /locus_tag="ACL3R8_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR1314017.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            38888..39844
                     /gene="lytA"
                     /locus_tag="ACL3R8_001136"
     CDS             38888..39844
                     /gene="lytA"
                     /locus_tag="ACL3R8_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR1314018.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            40190..40351
                     /locus_tag="ACL3R8_001137"
     CDS             40190..40351
                     /locus_tag="ACL3R8_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1314019.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            40338..40544
                     /locus_tag="ACL3R8_001138"
     CDS             40338..40544
                     /locus_tag="ACL3R8_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314020.1"
                     /translation="MDLSNKASNLRKKLGADGESSIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            40557..40946
                     /locus_tag="ACL3R8_001139"
                     /pseudo
     CDS             40557..40946
                     /locus_tag="ACL3R8_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            41077..41502
                     /locus_tag="ACL3R8_001140"
     CDS             41077..41502
                     /locus_tag="ACL3R8_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314021.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            41910..42695
                     /locus_tag="ACL3R8_001141"
     CDS             41910..42695
                     /locus_tag="ACL3R8_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314022.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPFVSEFWNDFKNNH
                     DKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            42685..>43198
                     /locus_tag="ACL3R8_001142"
     CDS             42685..>43198
                     /locus_tag="ACL3R8_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314023.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTIKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQP"
BASE COUNT        12651 a         7879 c         9493 g        13175 t
ORIGIN      
        1 aattggagaa ttactcaaga ggctgaagag gacggtttgc taaatcgtta ggtcgggtaa
       61 ctggcgcaag ggttcgaatc ccttattctc cgttttaatg agagtttgta actctctttt
      121 ttgtttttag agacaataaa acttcagatc cgtaaaactt aattgaatta ctaatctgaa
      181 gttattttta tatcgtttat attataattg tgttatttta cttccaacta ttgagagaaa
      241 tttcgccact atttagccag atttcttttc cgttatcaca ttgaattaaa agttttccat
      301 tttctgagat gtctttagca agtcccttgt agtctttttg ctctagtgtg aaagtgactt
      361 cttttcctag aatgaatgac tgttttttgt ataggtataa tagctcttct gctggtgttt
      421 cgaagaaagc acgccagatt tctatgatca attcattcct tgttatagga gctgtagctt
      481 taaataagct ggcagctttt tcttttaatt cctgagggaa gtctttaata gtgaaattga
      541 tacctactcc aataatgata tctgtgacta agccagtttc tacagaggtc attgcttcag
      601 taaggattcc tccaatttta tgattgttta gatagatatc attgacccat tttatgtcga
      661 catctattaa agttaggttc ttaatagctt tgtagacagc tccagctaca agtagtgtgt
      721 aggatggtaa tttgtcatag gggagatttg gtttaagatg gagtgtcata taaataccac
      781 cttgtggtga gtagaaggaa cgttgaaaac ggcctcggcc tgctgtttga taggaagcta
      841 gatagagggt atttgcttca tggcctaaat caattgcttc ttttgcatct agttgtgttg
      901 attttgtttc gggtttaaag ctgactttaa ttggaagatt ttcttctaga atctctggaa
      961 gaataaggtc accattcatc aatttatatc ctctattttt gatactatca atttcaatgc
     1021 cttcttgttc tagtcgcttg atggctttcc aaattgatgt tcggcttagg gatagttttt
     1081 ctgcgatttt ttctccgctg atatagtcgg tttctttaga taggatttgg tagacagctt
     1141 ggtaggattt cataatgttg cctttctcac tagttggtat tgagagtatt cttttcttgt
     1201 atgacttgga gtctgattaa agtattgttt ataagctttc gaaaaatgga gtggatctga
     1261 aaaacctacc gagtatgcaa ttaccttgat ggactcttgg gtattttcga gaagttgtct
     1321 agctcggtgc attcgaacgt agagtaggta ttctttgggt gataaggtat taaattcttt
     1381 gaatacgctt gataagtagc ttctgtgaac ggatagttct tttgctaaat cttgaattgt
     1441 aagtgattga ggatagtggc tatcaattaa tcgtttgcat tcaagataga gttggtgggt
     1501 tgatgaaata ttcttttttt tctgattggg agcaatagtt cccatatgaa acatcagttc
     1561 atgaagttgt cccatgatat ggagttgagc taattcactt gattttgtaa tctgagcgaa
     1621 gcggacaatg tctgagatga gttttgcagt agtctgggta tgacaagttt cagattggat
     1681 gagataggat tgatcagaaa tttgggaaag agcaaaataa tcaggggatt tccctccagt
     1741 gattcctaac cagtagtagg cccaaggttc tttactatct gcttgataaa aggttagttc
     1801 ctctggtttt aatagaaaga aatctccttc ttttaaatca acaattttac ccttgtaata
     1861 aaattttcct tgtcctttag taatgtaatg tagaacgtat gtatcacgaa tggctggacc
     1921 aaaagagtaa ttaggtgtgc attcctcata tccataaaag cttagggcaa ggtcgattgt
     1981 tccagtctgg tattctgaaa aaactaacat gtgctacctc ctacctaaca ttttaccata
     2041 ttcttgagac atttttctat tttggaaagc gatttcaggt gataaaatat aatcaataaa
     2101 gtgatgaggt gaagtaaatg ggagttagga tagagaataa tctattttat gttgagagta
     2161 aaaatctaag tttgattatt gaaaatcgaa atggctactt acttttgaaa catttaggaa
     2221 agactattaa gaactataaa ggttccaata gtgtttatga acgagaccat gccttttcag
     2281 gaaatccaac ggctactaat cgaaccttta gtttagatac tcagcgacag atttttggac
     2341 aacatggctt aggagatttt aggaaaccaa ccatacaggt tcagcatagt gtaactgaag
     2401 taacagactt tcgatttgta gaagcaaaga ttttaaaagg tcagaatggt ccacagggct
     2461 taccttctcc acatagcatg gacgatacag agactcttgt cttaatgtta gaagattcta
     2521 aggctcaact tagtctgact ttgtattata ctacttttaa taatgatgcg actattgcta
     2581 gctacagtaa attagataat aatagtaatc aggaagttgt catccataaa gatttttctt
     2641 ttatggctga ttttccagct gcagattacg aaatagtaac tctgcagggt gcttatgctc
     2701 gtgaaaagac tgttagacgt caacaggtag aacaaggaat cttttcgatt agctcaaacc
     2761 gaggtgcttc tggtcatgct caaacaccag ctcttctact atgcgaacaa ggagtcacag
     2821 aggatgctgg gaatgtgttt gctattcaac taatgtatag tggcaacttt gaagcttttg
     2881 ttcaaaaaaa tcaattgaat gaagttcggg tggctattgg cattaatcca gaaaactttt
     2941 cttggaagtt agctcctgag gaatactttg aaacaccggt agctttagtg acccattcag
     3001 atcagggatt aactggtatt agtcatgaaa gtcagaattt tgtactgaag cacattatgc
     3061 taagtgaatt ttctaaaaaa gaacgtccaa ttctaatcaa taactgggaa gctacttact
     3121 ttgactttca gatagaaaaa ctgttagagt tagcagatga agctaagaaa gttggcattg
     3181 aactttttgt attagatgat ggttggtttg gcaatcgttt tgatgataat cgtgctttag
     3241 gtgattgggt tgttaatgag gaaaaactgg gtggaagtct agaaagtctg atttcagcta
     3301 tccatgaaag aggtttgcag tttggacttt ggttagaacc cgaaatgatt tctgtagata
     3361 gtgatttgta tcgtcgacat cctgactggg ctattcaggt tcctgactat gagcatactt
     3421 attctcggaa tcaattagta cttaatcttg ccaatcctca ggtagtagaa tacttgaaaa
     3481 gtgtcttaga tcaactccta tcttatcatg atattgatta cattaaatgg gatatgaacc
     3541 gcaatatcac taagctaggg aatggattaa cttatctaga gacacagatg caatctcatc
     3601 agtacatgct ggggctttac gaactcgttt cttatctgac agagaagcac agccatattc
     3661 tctttgagtc ctgctctggt ggtggtggac gaaatgatct tggtatgatg cgctatttcc
     3721 cacaagtttg ggctagtgat aatactgatg ccattgcacg tttaccaatt caatacggtt
     3781 catcctatct ctatccaacc atttctatgg gggctcatgt gtcagcagta ccgaatcatc
     3841 agatgggacg aatgacacca ttagaaacac gtggccttgt agcaatgatg ggaaatttgg
     3901 gctatgaact tgatttgaca aatttatcag atgaagagaa agctacgatt gctaatcagg
     3961 tgaacttgta taaagaatta cgaccagtag ttcagttagg acagcagtat agactaatta
     4021 atcctgatac tgtatccaat gaagcagctg tacaatttaa ttacgaaaat caaacgattg
     4081 taacctacgt tcgcgtttta tctgttgtag agaccatgga aacaacttta aaattaaaag
     4141 atttggatga agagggacta tataaattac aggaaaatgg cgaagtttac tcaggtgcag
     4201 aactaatgta tgcgggccta actgttatct tatcccaagg agattttttg agtagacagt
     4261 atatttttag aagactatga taagggtgta taaatttata aaggaggctt tctaatggaa
     4321 tggtataaaa aaatcggact tcttgcaact acaggtttag ctttggttgg gctcggcgct
     4381 tgctccaact atggtaaatc tgcggatggc acagtgacca tcgagtattt caaccagaaa
     4441 aaagaaatga ccaaaacctt ctcaaaatca ctcgtgattt tgagaaggaa aaccctaaga
     4501 tcaaggtcaa agtcgtcaat gtaccaaatg ctggtgaagt attgaagaca cgcgttctcg
     4561 caggagatgt gcctgatgtg gtcaatattt acccacagtc catcgaactg caagaatggg
     4621 caaaagcagg tgtctttgaa gatttgagca acaaagacta cctgaaacgc gtgaaaaatg
     4681 gctacgctga aaaatatgct gtaaacgaaa aagtttacaa cgttcctttt acagctaatg
     4741 cttatggaat ttactacaac aaagataaat tcgaagaact gggcttgaag gttcctgaaa
     4801 cctgggatga atttgaacag ttagtcaaag atatcgttgc taaaggacaa acaccatttg
     4861 gaattgcagg tgcagatgct tggacactca atggttacaa tcaattagcc tttgcgacag
     4921 caacaggtgg aggaaaagaa gcaaatcaat accttcgtta ttctcaacca aatgccatta
     4981 aattgtcgga tccgattatg aaagatgata tcaaggtcat ggacatcctt cgcatcaatg
     5041 gctctaagca aaagaactgg gaaggtgctg gctataccga tgttatcgga gccttcgcac
     5101 gtggggatgt cctcatgaca ccaaatgggt cttgggcgat cacagcgatt aatgaacaaa
     5161 aaccgaactt taagattggg accttcatga ttccaggaaa agaaaaagga caaagcttaa
     5221 ccgttggtgc gggagacttg gcatggtcta tctcagccac caccaaacat ccaaaagaag
     5281 ccaatgcctt tgtggaatat atgacccgtc cagaagtcat gcaaaaatac tacgatgtgg
     5341 acggatctcc aacagcgatc gaaggggtca aacaagcagg agaagattca ccgcttgctg
     5401 gtatgaccga atatgccttt acggatcgtc acttggtctg gttgcaacaa tactggacca
     5461 gtgaagcaga cttccatacc ttgaccatga actatgtctt gaccggtgat aaacaaggca
     5521 tggtcaatga tttgaatgcc ttctttaacc cgatgaaagc ggatgtggat taggagtaga
     5581 gagactatga aaaaagtatt acaaaaatat tgggcatggg cttttgtggt catccccctc
     5641 ttgttacaag caattttctt ctatgtgccg atgtttcaag gagcctttta cagttttacc
     5701 aactggacag gattgactta caactacaaa tttgtcggct taaacaactt taagctcctc
     5761 ttcatggatc caaaattcat gaatgcgatt ggctttaccg caatcattac gattgtcatg
     5821 gtggttggtg agattgcact cgggatcttc attgcgcgtg tcttgaactc taaaatcaaa
     5881 ggccaaacct tcttccgtgc ttggttcttc ttcccagctg ttttatctgg tttgacagtg
     5941 gctttgatct tcaagcaagt cttcaactac ggtcttccag cgattgggaa tgcccttcat
     6001 attgaatttc tccaaaccag tcttttaggg actaagtggg gagcaatctt tgcggctgtc
     6061 tttgtccttc tttggcaagg ggtggctatg cccatcatca tcttcctagc tggtttgcaa
     6121 tctattccaa ctgagattac agaggcagca aggattgatg gtgcgactag caagcaagtt
     6181 ttctggaaca ttgaattgcc ttacttgcta ccaagtgtct ctatagtctt tatcctagcc
     6241 ctaaaaggtg ggctgactgc ctttgaccaa gtctttgcca tgaccggtgg tggtccaaac
     6301 aatgccacaa cctcacttgg gctcttggtt tataactatg cctttaaaaa caaccaattc
     6361 ggttatgcca atgccattgc cgtaatcttg ttcttcttaa ttgtagtgat ttcgatcatc
     6421 caattgagag tatctaagaa atttgaaatt taagaggaga agcatgatga aacaagatga
     6481 aagaaaagcc ctgattggca aatacattct attgattcta ggatcggttc tgattttagt
     6541 gccgctcctt gctaccctct ttagttcctt caaacccact aaggatattg tagataattt
     6601 ctttggcttt ccaaccaact tcacatggga caactttagc cgtctcttag ctgatgggat
     6661 tggaggctat tattggaact ctgtcgtcat cactgtctta tctttacttg cagtaatgat
     6721 ctttatacct atggcagcct actccatcgc tcgcaatatg agtaaaagaa aagcctttac
     6781 catcatgtat accctcttaa tcctcggaat cttcgtacct ttccaagtca tcatgattcc
     6841 gattacggtt atgatgagta aactcggttt ggctaatacc tttggtttga tcttactcta
     6901 cttgacctat gcgattccac agaccctctt tctctatgtt ggctatatca aaatctcgat
     6961 tccagaaagt ctggatgaag cagcagagat cgatggggct aatcaattta caacctattt
     7021 ccgcatcatc ttcccaatga tgaaaccgat gcatgcgaca accatgatca tcaatgccct
     7081 ttggttctgg aatgacttca tgttgccact ccttgtcttg aaccgggatt ccaaaatgtg
     7141 gactctgcct ttgttccaat acaactacgc aggccaatat ttcaacgact acggaccaag
     7201 ctttgcctct tacgtggtcg gcattatcag tatcaccatt gtctatctct tcttccaacg
     7261 ccatatcatt tcaggaatga gcaacggggc agtgaagtaa tactcaatga aaatcaaaga
     7321 gcaaactagg aagctagccg caggctgtac ttgagtacgg taaggtgaag ctgacgtggt
     7381 ttgaagagat tttcgaatag tataagaaga gctcatggaa tctatagtct ttgacacaga
     7441 ggaagagttc agcttgttga taattctatg tagaaaacaa gaaagtagta ctttgtttat
     7501 cacagtctat attagtacga gtttgatgat aaatagagat ttaaaatgaa ttttatttat
     7561 gaagccagat catatgatac ttggcttcaa ttagaaaaag gagagtaatg atgccaattc
     7621 aaaataaaac catgttgatt acctattctg atagccttgg aaataatctt aaagacttat
     7681 atgataattt ggaagagcat tttggagatg ctattggagg agttcacctt ttaccatttt
     7741 tcccatcaac aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg gactcagctt
     7801 ttggtgattg ggaggatgtt aagcgtttag gtgagagata ttatcttatg tttgatttta
     7861 tgattaatca tatttctcgt caatccaagt attataagga ctatcaagaa aaacatgaag
     7921 ccagtgaatt taaagctctc tttttaaact gggataagtt ttggccagaa aaccgtccga
     7981 cacagtctga tgtagattta atttacaagc gtaaggatcg tgcaccaaag caagagattg
     8041 tgtttgaaga tggttcagtg gaacatttgt ggaatacctt tggtgaggag cagattgatc
     8101 ttgatgtgac caaagaagta actatggaat ttatccgtaa gaccattcag cacttggcaa
     8161 gtaatgggtg tgatttgatt cgtctagatg cctttgctta tgcagtgaag aaattggata
     8221 ctaatgattt ctttgtggaa ccagatattt gggatttatt ggacaaagtt cgagatatcg
     8281 ctgctgagta tgggacagag cttttacctg agattcatga acactattcg attcagttta
     8341 aaatagcaga ccatgattac tatgtttatg attttgctct tccaatggtg acactttata
     8401 ctctttacag ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc
     8461 aatttacgac gctagatacc catgatggga ttggagtagt agatgtcaag gatatcctga
     8521 ccgatgagga gattgactat gcttcaaatg aactctataa ggttggagcc aatgtcaaac
     8581 gtaagtactc tagtgccgag tataacaact tagatatcta ccaaatcaat tcaacctact
     8641 attcagcgct tggagatgat gatgtcaagt attttctcgc tcgtctaatt caagcttttg
     8701 ccccaggtat tcctcaggtt tactatgtgg gtctattagc aggcaagaat gacttgaaat
     8761 tattagaaga aactaaagaa ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa
     8821 tagcaaaaga agtgcaacga cctgttgtga aggcccttct caatctattt tctttccgta
     8881 accgttcaga agcctttgat ctagaaggga ctactgagat agagacacca acagctcaca
     8941 gcattgtaat caaacgtcaa aataaagata agtccgtaac agcagtagta gaaattgatt
     9001 tgcaaaatca gacttatcgg gtaattgaga atggagttga agtatcattt tgaagccttg
     9061 atatggtgga taaaataggg tttttatttt ggaaaacgtt tcctttgttt tcaaattgct
     9121 aaaaaagtgg tacaatatag gatagcttac tattatctga atcagctgat ttggagagaa
     9181 aggattcatt ttgaaatcaa taggctttat tgaaaagctg aaggggttgt ctagtaaaga
     9241 gctgatttta ttgggaatta tcctaagtat ctttttaccc ttttatcttt ttgtagttgt
     9301 actctgttta tatattatca gtttgatttt tacaggagac atgaaaagta ttcttcagaa
     9361 aatgggggag catccgatgc tgcttctttt tcttagctat agtactgtta tatccattct
     9421 tgcacaaaat tggatgggtc ttgtggcttc agtaggaatg tttctattta ctattttctt
     9481 tttgcactat cagtcgattt tatcccataa attctttcga ttgattttgc agttcgtctt
     9541 gtttggtagt gtcttgtcag ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa
     9601 atttaactat gcttttcttt cacccaatat gcaggtgtgg catcagaacc gggcagaagt
     9661 gaccttcttt aatcctaatt attatggaat tatttgttgt ttctgtatta tgattgcttt
     9721 ctatctgttt acaacgacca agttgaattg gttgaaagta ttctgtgtga ttgcaggctt
     9781 tgttaatctc tttggtttga actttactca aaatcgaact gcctttcctg ctattatcgc
     9841 tggagcaatt atctatctct ttacgactat taaaaactgg aaggcctttt ggcttagtat
     9901 tggggtcttc gcgattggtt tgagtttcct cttttctagt gatttgggag ttcgaatggg
     9961 tactttagac tcttctatgg aagaacgcat ttctatctgg gatgctggga tggccttgtt
    10021 taagcaaaat cctttttggg gtgaagggcc attgacctat atgcactctt atcctcggat
    10081 acatgctcct tatcatgaac atgcccacag tctttatatt gatacgattc tgagttacgg
    10141 aattgtgggt accattttat tagttttgtc ttctgttgct cctgttcgct tgatgatgga
    10201 tatgagtcag gagtcgggga aacgtccgat tatcggcctt tatctatctt tccttacagt
    10261 ggttgctgtg cacggaattt ttgacttggc tctcttctgg attcagtcag gctttatttt
    10321 cttgctagtt atgtgcagta ttccattgga gcatcgaatg ttggtatcgg acatgacgga
    10381 ttaagtttta taagtttgaa atcttctacc ttgggtagga gattttttta tactatgggc
    10441 atgtcgtgca tctgaggtgt aagtcctctg tagggatcca ctaccggtga atacaatagc
    10501 gctccccaag cctgactgtc gtgaggtagc ggattaaaat ggtctgggga tagatcgttt
    10561 taagtctgac gcaggaaata agaattgtca gagaaagcaa tagtgaaatc gtaggctatg
    10621 aatagaaacg tgatagcgag gagcatatag tggataaggt agcgagaaat tttaaagtat
    10681 aaaagatagt cttaatctat atatgtaaat cacaaaagta attgaattcg gaataaggtt
    10741 ggtgtgaaaa gacatagtaa actgaatctt gaatactaga atgatacttc tacaatattg
    10801 ttataattta atttgaattc caaaatcaca ttgttccgtc cgtatttcat tttactgtat
    10861 gtcttcctaa actccaaagt ttctgcgtca aatttcctat tttcactgta gtctttgaca
    10921 cttcgaacga caatttgaat catatattca aaaaaaatga aaaatttgtg ccaacaagcc
    10981 taaatattct gaaaatttgt ttgattttta atggataatg tgatataatg gttgtcaatc
    11041 tataattcac ataaacagag gagtagaaaa tgaaaaaaaa tcgtgtattt gctacagcag
    11101 gtcttgtttt attagcagca ggtgtacttg cagcatgcag ttcttcaaaa tcatctgatt
    11161 catcagcccc taaagcttat ggctatgttt atacagcaga cccagaaacc ttggactacc
    11221 tgatttcaag taaaaatagt acaacagtag tgacttcaaa tgggattgat ggtttattca
    11281 ctaacgataa ttacggtaat cttgctcctg cagttgcaga ggattgggaa gtctctaagg
    11341 atggtttgac ctacacttat aagattcgta aaggggttaa atggtttacc tctgatggag
    11401 aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg tttaaaacac gcagcagata
    11461 aaaaatcaga agctatgtat ttagctgaaa attcggttaa aggcttggca gattatctat
    11521 caggaacttc aacagatttt tcaacagttg gtgtcaaggc ggttgatgat tatacgttac
    11581 aatacacttt gaaccagcct gaaccgttct ggaactctaa gttgacctat tctattttct
    11641 ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga ttttgctaaa ccaacagatc
    11701 cgacatcctt gctttataat ggtccattct tgttgaaagg gttgactgca aaatcttctg
    11761 tagagtttgt aaaaaatgag caatattggg ataaagaaaa tgtccaccta gatactatca
    11821 atctagctta ctatgatgga tcagatcagg agtcgctaga gcgtaacttc actagtggag
    11881 cttatagtta tgcccgtctt taccctacca gctccaacta ttctaaggtt gcagaagaat
    11941 acaaggacaa tatctattac acacaatcag gctctgggat tgctggtctg ggtgtgaata
    12001 ttgatcgcca aagttacaac tatacttcta aaactacaga ttcagagaaa gtagctacta
    12061 agaaggcatt gcttaacaaa gatttccgtc aagccttgaa ttttgctctt gatcgctcag
    12121 cttactcagc tcaaatcaat ggtaaagatg gagcagcttt agcagttcgt aatttatttg
    12181 taaaaccaga ctttgtttca gctggtgaga agacctttgg tgatttagtc gctgctcaac
    12241 ttcctgctta tggtgatgag tggaaaggtg tgaatttagc tgatgggcag gatggtttat
    12301 tcaatgctga caaggccaag gcagagtttg cgaaagctaa gaaagcttta gaagcagacg
    12361 gcgttcagtt tcctattcat ctggacgttc cagtagacca agcatcaaaa aactacatat
    12421 ctcgtattca gtcctttaaa caatctgtag aaacagttct tggtgttgaa aatgtcgttg
    12481 ttgatattca acaaatgaca agtgatgaat tccttaatat tacttactat gctgccaatg
    12541 cttcatctga ggattgggat gtatcaggag gagtttcatg gggtccagac tatcaagacc
    12601 catctactta cctggatatt ttaaaaacaa ctagcagtga aactacaaaa acatatttag
    12661 gatttgataa tccaaatagc ccttcagtag ttcaagttgg tttgaaagaa tacgataaat
    12721 tagttgatga agctgccaga gagacaagcg acttgaatgt ccgttatgaa aaatatgcag
    12781 cggctcaagc atggttgaca gatagttcac tctttattcc tgctatggct tcttctggtg
    12841 cagcaccagt gctttcacga attgttccat ttactggagc ttctgcgcaa acaggctcta
    12901 aggggtcaga tgtttacttc aaatatttga aattacaaga taaagtggtg actaaggaag
    12961 agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc tgaatcaaat gagaaagctc
    13021 aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa tagaactttc tctccatgag
    13081 gagaaggttc ttttgggatt tttaaaggaa ataatatgaa aaaatatatt tttatgcgtg
    13141 ttttgcggtc attggtttcg attttcttag taacgacttt gacctacacg attatctata
    13201 ccttggttcc tcgaaaattg attttcaagc aggatcctaa ctataataaa attgcgacaa
    13261 cggctgataa acgtgataac tatgaaaata ctgtgtttga gcgtatgggc tacattgagt
    13321 attacgatac taaagagttg caagaaaagg caagtagcat ggattcttct gtaacagtag
    13381 aagcaaatgc gaccaataaa gctatttatg aaaagtacat caatcaatta ggtcatggtt
    13441 ggactttggg agaatttact gaaagtggtc aattctatgc tactcgtgaa attccaattt
    13501 ttgaacgtgt ttttcacttc tatgctaact tgattgacat tgaccataca aataaaatcc
    13561 aagaccctga aaatccagac ttgaaacgct accttcgttt tgaaaatgat ccagctatcg
    13621 gatggtcatt ggtcggttca ggaactaaac ataaatatct cttgtacttt aacagtcagt
    13681 tcccatttgt tcatcaaaac tttgtgaact tgaatttagg tgactcttac ccaacctatg
    13741 ctaatacacc agttcttcag gttattactc aaggtcaagg acaaaccaaa actgcccaag
    13801 ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat ttactcaaga acctacaagt
    13861 cacctagtca ggctgactct cgtgaagtag ctagctatgg gaaagatgat ccttatacag
    13921 cgactgaaag taattaccaa tatccatcta tgattgtcag ctctgctatt actggtttga
    13981 ttggtttggt tcttgcctat gctcttgccg tgccacttgg ttcagccatg gctcgtttca
    14041 agaacacttg gattgatagc ctatcaacag ggactttgac cttcttgctt gctcttccaa
    14101 cgattgcctt ggtttacatc gttcgattga ttggatcatc tattgccctt ccagattcat
    14161 tccctatctt gggagctgga gattggcgtt cttacgtttt accagcagtc atccttggtt
    14221 tgttgggtgc tcctgttaca gccatttgga ttcgtcgtta catgattgac ttgcaatctc
    14281 aagactttgt tcgtttcgct cgtgcaaaag gtttgtctga aaaagaaatt tcaaacaaac
    14341 acatctttaa aaatgccatg gttccgctgg tttcaggaat tcctggtgcc attattgggg
    14401 ttatcggtgg tgcaaccctt actgaaacag tcttcgcctt cccaggtatg ggtaaaatgt
    14461 tgattgactc tgtaaaagca tctaataact ctatggtcgt tggtcttgtc ttcatcttta
    14521 catgtatttc tatcttctca cgtcttttgg gagatatttg gatgactatt attgacccac
    14581 gtattaaatt gactgagaaa ggaggcaaat aatgtctaca atcgataaag aaaaatttca
    14641 gtttgtaaaa cgtgacgatt ttgcctctga aactattgat gcgccagcat attcttactg
    14701 gaaatcagtg tttaaacaat ttatgaagaa aaaatcaact gtagtcatgt tgggaatctt
    14761 ggtagccatc attttgataa gtttcatcta cccaatgttt tctaagtttg atttcaatga
    14821 tgtcagcaag gtaaacgact ttagtgttcg ttatatcaag ccaaatgcgg agcattggtt
    14881 cggtactgac agtaacggta aatcgctctt tgacggtgtc tggttcggag ctcgtaactc
    14941 catcctcatt tctgtgattg cgacagtgat taacttggtt atcggtgttt ttgtcggtgg
    15001 tatttggggt atttcaaaat cagttgaccg tgtcatgatg gaagtttaca acgtcatctc
    15061 aaacatccca cctcttttga ttgttattgt cttgacttac tcaatcggag ctggattctg
    15121 gaatctgatt tttgccatga gcgtaacaac atggattggt attgccttca tgatccgtgt
    15181 gcaaatcttg cgctatcgtg acttggaata caacttggcg tcacgtactt tgggaacacc
    15241 aaccttgaag attgttgcca aaaatatcat gcctcaattg gtatctgtta ttgtgacaac
    15301 catgactcaa atgcttccaa gctttatctc atacgaagcc ttcttgtctt tcttcggtct
    15361 tggattaccg attacagtgc caagtttggg tcgtttgatt tcggattatt cacaaaacgt
    15421 aacaaccaat gcttacttgt tctggattcc attgacaacc cttgtcttgg tatccttgtc
    15481 ccttttcgta gttggtcaaa acttagcgga tgctagtgat ccacgtacac atagatagga
    15541 gtagaaatga caaaagaaaa aaatgtaatt ttgactgctc gcgatattgt cgtggaattt
    15601 gacgttcgtg acaaagtatt gacagccatt cgcggcgttt cccttgaact agtcgaagga
    15661 gaagtattag ccttggtagg tgagtcagga tcaggtaaat ctgttttgac aaagaccttc
    15721 acaggtatgc tcgaagaaaa tggtcgcatt gcccaaggta gtattgacta ccgtggtcag
    15781 gacttgacag ctttatcttc tcacaaggat tgggaacaaa ttcgtggtgc taagattgcg
    15841 actatcttcc aggacccaat gactagtttg gaccccatta aaacaattgg tagtcagatt
    15901 acagaagtta ttgtaaaaca ccaaggaaaa acagctaaag aagcgaaaga attggccatt
    15961 gactacatga ataaggttgg cattccagac gcagatagac gttttaatga atacccattc
    16021 caatattctg gaggaatgcg tcaacgtatc gttattgcta ttgcccttgc ctgccgacct
    16081 gatgtcttga tctgtgatga gccaacaact gccttggatg taactattca agctcagatt
    16141 attgatttgc taaaatcttt acaaaacgag tatcatttca caacaatctt tattacccac
    16201 gaccttggtg tggtggcaag tattgcggat aaggtagcgg ttatgtatgc aggggaaatc
    16261 gttgagtatg gaacggttga ggaagtcttc tatgcccctt gccatccata tacatggagt
    16321 ctcttgtcta gcttgcctca gcttgctgat gataaagggg atctttactc aatcccagga
    16381 acacctccgt cactttatac tgacctgaaa ggggatgctt ttgccttgcg ttctgactac
    16441 gcaatgcaga ttgacttcga acaaaaagct cctcaattct cagtatcaga gacacattgg
    16501 gctaaaactt ggcttcttca tgaggatgct ccaaaagtag aaaaaccagc tgtgattgca
    16561 aatctccatg ataagatccg tgaaaaaatg ggatttgccc atctggctga ctaggaggaa
    16621 ggaaatgtct gaaaaattag tagaaatcaa agatttagaa atttccttcg gtgaaggaag
    16681 taagaagttt gtcgcggtta aaaatgctaa cttctttatc aacaagggag aaactttctc
    16741 gcttgtaggt gagtccggta gtgggaaaac aactattggt cgtgctatca tcggtctaaa
    16801 tgatacaagt aatggagata tcatttttga tggtcaaaag attaatggta agaaatcgcg
    16861 tgaacaagct gcggaattga ttcgtcgaat ccagatgatt ttccaagacc ctgccgcaag
    16921 tttgaatgaa cgtgcgactg ttgattatat tatttctgaa ggtctttaca atcaccgttt
    16981 atttaaggat gaagaagaac gtaaagagaa agttcaaagt attatccgtg aagtaggtct
    17041 tcttgctgag cacttgactc gttaccctca tgaattctca ggcggtcaac gtcaacgtat
    17101 cggtattgcc cgtgccttgg tcatgcaacc agactttgtt attgcagatg agccaatttc
    17161 agccttggac gtttctgtac gtgcccaagt cttgaacttg ctcaaaaaat tccaaaaaga
    17221 gctcggcttg acctatctct tcatcgccca tgacttgtcg gttgttcgct ttatttcaga
    17281 tcgtatcgca gttatttaca agggtgttat tgtagaggtt gcagaaacag aagaattgtt
    17341 taacaatcca attcacccat atactcaagc cttgctttca gcggtaccaa tcccagatcc
    17401 aatcttggaa cgtaagaagg tcttgaaggt ttacgaccca agtcaacacg actatgagac
    17461 tgataagcca tctatggtag aaatccgtcc aggtcactat gtttgggcga accaagccga
    17521 attagcacgt tatcaaaaag gactaaacta ataatggttt tataatttcc atgtcaattt
    17581 ttatggaaat tataaaactt tttttgttgg actgatttga aaaactttga aagcttcctg
    17641 aaagaatttt cgaaaaattt taaaaaattc tgaaatatta ttgacaggtg atgaaaaagg
    17701 tggtaggata ggaagcatca aaaaagaaag cagaaaaaga aatgaataag agacaagccg
    17761 taactatgaa tcaaaacttt tactttagct actttagata gtgtttgtag acatgtcacc
    17821 atggatgcaa acagttcaag caatttgttt gtatctatgt ggctaagatt tttgattgtg
    17881 gtccatatag atgaatatct aaatggacta gctaagttgt aacttgttag gttatttcaa
    17941 gtatccgttt agatagtatc taggcggttt tttgttttat cttttctgag aaggagtttc
    18001 attatgaaag ttgttcgaaa atcactagcc ccctcttggt agtggggctc ctcttgactt
    18061 ctctgatcag tttgcatcag ttgaaggcag ataagaaaaa gatgtctttc gtatcggtat
    18121 ttcgcaattt attacccacc agtccttaga cgctactaga gaagaatttg tggatgagct
    18181 ggccaaacaa ggctatgttg agggggaaaa tattgagatt gatttgcaaa atgtacaggg
    18241 agaacaaaga aatctaaaaa cgatttccca gcaactagca gaatccagcg atgtcgttct
    18301 agccatcgca aggccttctg ctcagagctt ggccaatacg acgcaaacga caccagttat
    18361 cttttcagct gtaacagacc cagtcagtgc caagttggtt gagtcaagag aacatcctgg
    18421 gggcaatgta actgggacaa gcgatcagtc atcagatgcc atttcaaccc aaatcaattt
    18481 gataaagaaa gtgttgccaa aggctaaaac gattggaatc ctctatactc agagcgagcc
    18541 caattcggtt gtttaaaatg atgaagctaa gcgacttctg aaagaaaaag gctttaccgt
    18601 tgttgaaaaa acaatcttgg acagtaataa cgtcaaggcg gcagcagaga gtttgatggc
    18661 agaggtggat atggtttttg tcccaactga taatatcatt tcgtcaacca tggaaacagt
    18721 taagcaggtt tctattaaac acaaggttcc agtattcggt ggttcaacag aaatgattgc
    18781 tgttggtgac ttgtataact acggaaccaa ttatgaagaa ttgggaagac agacagctcg
    18841 catgctgatt cgtgttttaa aaggtgagaa accagaaaat atagcagttg agttgcctga
    18901 aaaactggaa ttgcatacca atcaagaaat ggcagatgca ttgggaattg atattagtaa
    18961 gttagaaggc aaggaataag gaggattaag atgaattttg tgttatctag tttatcagaa
    19021 ggtttgttgt ggtcgattgt ggcgattggg gtctacttga ctttccgtat tttggatatt
    19081 gcggatataa ctgctgaggg agcctttcct ctgggggcag cagtcgttgt atcacagata
    19141 caggcagggg cagatccttg gcttgcgact ttacttgctt tgctggcagg tatggtagca
    19201 ggtcttgtat caggaatgct ccacaccaag atgaaaatcc cagctctctt gacagggatt
    19261 gtgaccttga cagggctcta ttcaatcaat attaaaatta tgggcagtgt acccaatctt
    19321 tccttgggag attctgcaac cgtctttaaa cagttggcga gcttgggtct gacaaatgaa
    19381 ggagctgttt tctcacttag tttagtctgt ctcttacttg tttggtcttg acccttttga
    19441 tgaaaacaga gattggtttg gtcttgcgtt cgactgggga taatatcccg ataagtgagg
    19501 ccaatggagt caatgtagac accatgaaga ttgttggtta catgatttca aacggtttga
    19561 ttgccctatg tggttccttg tttgcccaaa atgatggatt ttcagatgtg acttctggga
    19621 caggaaccat tgttgttggt ttgagctcgg aagtcttgat acacgacttg accattggag
    19681 gccgcttatt atccatcgga atcggtgcta ttgtttaccg tttgattatt ttaaatatct
    19741 atgaaattcc aaatctagat caaaacttgg tacgtctctt taatgcaatc ttgctcgctt
    19801 tggttttatt tgcaccagaa ttgcaaaaga gattaaagat tcgtggtctg aaattgagaa
    19861 atgaatagga ggagaaagtt atggcaagtt tgttaacact tgaaaatatt cacaagacat
    19921 ttgaagcagg gacggtcaat gagaaccatg tcctcaaagg attagattta gaggttgaag
    19981 agggagattt tatctatgtg attggtggaa atggagcagg aaaatccact ttgatgaata
    20041 tcttggctgg caatctatcg gtggacgaag gggaccttct actggcaggg aaatccatta
    20101 aaaatctgag tgtcagaaag agagccaagg atattgcccg tgtttttcaa tatcctaaga
    20161 tgggaacagc ttctcgtttg acgattgagg agaatatggc tattgccttg agacgtgggc
    20221 aaaagagagg acttggttgg ggtgtgaagg agaaggatag aatccagttc caagaggcct
    20281 tgaaggagtt gaatattggt cttgaaaacc gcttaaaagt agatactcaa tatctctcag
    20341 gaggacaaag acaggctttg accctagtca tggcagctct ggtgaaaccc aaacttttac
    20401 ttttggatga acatactgcg gcacttgacc cgaaaaccag tcaaatggtg atggacttga
    20461 cgcaaaagat tgtggagcac catcagtgga cgactttgat gattacccat gatatgaatc
    20521 atgcgattga gtacggcaat cgtctcatta tgctctatca aggcaagata gtggtggatg
    20581 tcaagggaga agagaaaaag catctgacag ttgaagacct tatgcatctc ttccagaaaa
    20641 atagtggcca aagtctggtc agtgatgaat tagttttggg ataaagaaaa aggctgagat
    20701 ctggtgtctc aatcttttat ttcttgcgtt ttgcaaaatc tacaaatcta aatttttcta
    20761 acttatggcg actttcggta aactgaaatt ggcgtccgtc ttggagatag acttttgatt
    20821 taatcgaaac gatataaggg tctttgccaa tgtccatgag aatcttgtct cggtcgcttg
    20881 agtggtcgat ggtgatttcc ttctgagcat aatcaataag gagtttgagg ccattttcta
    20941 tataagaata gatagactgc tcagcaattt ggcgagtgag atttggaatt agttccatat
    21001 ccagatagtc cgtatccaga acggatacca gatcatccac cacacgctgg cggaccacct
    21061 tccaaaccat ccgaaactct gggaaaccgg ttatcagtga ggatttttta tcaataataa
    21121 tcttgtccag actgaccacg ttggttttag agcgcagtcc aagttcttta actagttctt
    21181 ggtagctggt taggttggat acagggaaat tgacggtttc ttctttgacg acttgagaac
    21241 cttgccctct tatctttttg atcaatcctt cctcttggag gagagacagg gcctttcgga
    21301 cggtatcacg actcacttga tattgctcca taaggtcgtg ctcgctagga aggaaatctc
    21361 cgacagcgta agtctcgttt tgaatggttt cttggatttg cttaaataat tgttggtatt
    21421 tcttcatttt gcctgcttta ataggttttt agtctagttt aatgaacacc tgtatctatt
    21481 ttaccataca agtgctagaa aatttacaaa aaaacaccct ttttatacca aacaagttgc
    21541 agacaagttt ggtatcgttt acaatatact tatcaaatca aacttgcttt gacaagtata
    21601 aggagaatca aatgggaaaa tttgaacaag aagccaaaga tctgcttcag gcaattggag
    21661 gcaaagaaaa tgtgactgcc gtaactcact gtgcgacacg gatgcgcttt gttttaagag
    21721 atgataagaa ggctaatgtt aaagctatcg agtcaattcc agctgttaaa ggaactttta
    21781 caaatgcagg tcaatttcag gtaatcattg gaaatgacgt gcccatcttt tataatgatt
    21841 ttacagccgt ttcaggtatt gagggtgttt ccaaagaagc aaccaagtct gcagctaaga
    21901 gtaatcaaaa cgtggttcaa ggtgttatga ccactctggc ggaaatcttt actccgatta
    21961 ttccagcctt gattgttggt ggattgatcc tcggtttccg taatgtcttg gaaggtgtcc
    22021 attggtcgat gttggatggc aagaccatca cagaatcctc tcagttttgg gcaggggtta
    22081 atcacttcct ctggttgcct ggtgaagcta tcttccagtt cttaccagta gggattactt
    22141 ggtctgtttc tcgtaagatg ggaaccagcc aaattttggg aattgttctc ggaatctgtt
    22201 tggtatcgcc tcagttgctc aatgcctatg cggttgcttc aacgccagca gctgatatcg
    22261 cggcaaactg ggtttggaat tttggttatt ttactgttaa tcgtattggt taccaagtcc
    22321 aagttatccc agccttgctt gcaggtttga gtctgtctta tcttgaaatt ttctggcgca
    22381 aacatatccc agaagtcatt tccatgattt ttgtaccttt tttgtcattg attccagcct
    22441 tgattttggc tcatactgtt ttgggaccaa tcggttggac aattggacaa ggactttcat
    22501 cagttgtctt ggcaggttta actggtccag ttaaatggct cttcggtgca atttttggtg
    22561 ccctctacgc tccatttgtc atcacaggtc tgcaccatat gaccaatgcc attgatacac
    22621 aattgattgc ggatgctggt ggcactgccc tatggccaat gattgctctt tctaatattg
    22681 ctcaaggctc agccgtgttt gcctattatt tcatgcatcg ccatgatgag cgtgaggctc
    22741 aggtttcact tcctgcaacc atttcagcct atctcggtgt tacagaacca gctctttttg
    22801 gggttaacgt aaaatatatt tatccatttg ttgctgggat gactggttca gcccttgcag
    22861 gcatgttatc cgttactttt aatgtaactg cggcttctat tggtatcggt ggtttgccag
    22921 gtattctctc tattcaacct caatacatgc tgccatttgc aggaactatg ctagttgcga
    22981 ttgttgttcc aatgctcttg actttcttct tccgcaaggc tggtctcttt acaaaaacag
    23041 agggcgatac gaacttgcag gcagaattcg ttgctcaaga agaagcagaa tttgtgaacc
    23101 atgaaccagt agaacttact tcggtagaaa ttatcagccc actaactggc caagtgaaag
    23161 aattgagtca agcgacggat cctatttttg catcaggtgt catggggcaa ggtctagtca
    23221 ttgaaccaag ccaaggtgag ttgacctctc cagttaatgg gacagtgacg gttcttttcc
    23281 ctaccaagca tgccatcggc attgtctctg acgagggagt tgaattgctc atccacatcg
    23341 gtatggatac agtaggtctt gatggcaaag gttttgaaag tcttgtagtc caaggagatc
    23401 acgttacagt tggtcagcaa ctgattcgtt ttgatatgga tgtcattaag gctgcaggtc
    23461 tggtgacaga aactcctgtt atcatcacca accaagatgc ttatacagcg actattcccg
    23521 gaacttatcc gacaacgatc caagctggag catctctcat ggtcgctaca cgaatctaat
    23581 actcttcgaa aatctcttca aaccacgtca gctctatctg caacctcaaa atagtgtttt
    23641 gagcaacctg tggctagctt cctagtttgt tctttgattt tcattgagta taattgaaat
    23701 agcacaaata gggacggaag actgcttcct cccttttatc agaaaaggag aaacagatga
    23761 cacttgataa aggaaaagta gtctatcaaa tctatccaaa atcttacaaa gacaccactg
    23821 aaaacggtat tggggatttc cgtgggatta tcgaaaaaat tccctattta gccaaactag
    23881 gtgtggatat ggtctggctc aatccattct atccaagccc tcaacgggat aatggttacg
    23941 atatttcaga ttatatggca gtggatcctc tttttggtga tatggctgat tttgaggaaa
    24001 tggtgtgtgt cggtaaagag cacaagattg actttatgct ggacatggta cttaatcatt
    24061 gttcgacaga gcatgaatgg tttcagaaag ccctagctgg tgataagtat tatcaagact
    24121 ttttcttcat ccaagaccaa ccaacagatt ggcagtctaa gtttggtggt tctgcatgga
    24181 cgcctttcgg ggatactggg aaatactatc ttcacctatt tgatgagacc caggctgacc
    24241 ttaactggcg caattccaat gtccgtaagg agcttttcaa ggttgttaat ttctggcgcg
    24301 acaagggtgt caaaggtttc cgatttgatg tgatcaattt gatcggtaag gacgaggttt
    24361 cagtggactg tcctgaaaat gaagggaagc cagcttatac agacaaaccc atcgttcata
    24421 actatttgcg tatgatgaac caagccactt ttggatctga cgatagcttt atgacagttg
    24481 gggaaatgtc ttctaccacc atggaaaact gtgtcctcta ttcgtcgcct gatcgtcagg
    24541 aattatccat gacctttaat tttcatcacc tcaaggtgga ctataaggat ggacaaaagt
    24601 ggaccttggc tccctttgat tttgaagagt tgaagagtct ttaccatagt tggggtaagg
    24661 aaatgagtga taaagacggt tggagtgccc tcttttggaa caatcacgat caaccacgtg
    24721 ccttgaaccg ttttgtcgat attcaaaact tccgcaagga aggagccacc atgctagcag
    24781 ccagcattca cctgtcacgt gggacacctt atatctacat gggtgaggaa atcgggatga
    24841 ttgacccaga ctatgattct atggctgatt atgtggatgt cgaatcgctt aatgcctatc
    24901 agatgctctt agaagaagga aagagtcagc aagaagcctt ccagattatt caagctaagt
    24961 cgcgtgataa ttcacgcatt cccatgcagt gggatgcttc ggaaaatgca ggattttcaa
    25021 caggcactcc ttggttgaaa gctggtaaat cctataaata catcaatgta gaaaatgaaa
    25081 tccagggtcc gatttttacc ttctatcaag acttgattcg actgcgtaag gaaatgccaa
    25141 tcatttcaga aggaagttac aaaccagcct ttgaagatag caaacaagtc tacgcttttg
    25201 aacgccagtt tgaggatcaa aagttactag tgctcaataa cttttatgct aaagaagtgg
    25261 aaatcgactt gccagcagtc taccaaaatg gacagatttt gatatcaaac tatgaagatg
    25321 cagaagtgtc tgagaaaatt ctactcaaac cctatcaaac actggctatt tatgtaaatt
    25381 aatactcttc gaaaatctct tcaaaccgtg tcagttttat ctgcaacctc aaagcggtgc
    25441 tttgagcaac ctgtggctag cttcctagtt tgctctttga ttttcattga gtataaactt
    25501 agcaaggaga cctctttttc agaaaagcag ggttcttttt gctgtctatt ccatccctga
    25561 aagtgtagaa caaactggtc agggtggcta gtttgtggta taatgaaagg aactcaaaaa
    25621 gaaacaggag aaaaatgatg gatttacttt tagcaattgt attgattgtg ctagcttttc
    25681 taggaggagc tcttggagga atgtacttgg ttcgtaagca aatcgaaaaa gaatttgctg
    25741 acaacccacg tttgaatgct gaagcagttc gtactctttt gagtgcaaat ggtcaaaaac
    25801 caagcgaagc taaggtacaa caagtttacc accaaatcat ccgccaacaa aaggcagccc
    25861 ttgctaacaa taaaaagaaa aaataaataa ggaaaagtct gggatgaaag ttccagactt
    25921 ctcactatgt tggttatggt ttagggatga gactttttcc ttgcattcta ttgatatttg
    25981 attatgatta agagagaggt agttgacatt ctatcaagct gtcggtcagt tcgttcagta
    26041 caaggaatca taatgaacga tcaatcagaa aaaagactag aaagaagact gtatggataa
    26101 tcgaccaatt ggttttttgg attcgggtgt cgggggcttg accgttgtgc gcgagctcat
    26161 gcgccagctt ccccatgaag aaatcgtcta tattggagat tcggcgcggg cgccctatgg
    26221 cccccgtcct gctgagcaaa ttcgtgaata tacttggcag ctggtcaact ttctcttgac
    26281 taaggatgtc aaaatgattg tcattgcttg taacactgcg actgcggtcg tctgggaaga
    26341 aatcaaggct caactagata ttcctgtctt gggtgtaatt ttgccaggag cttcggcagc
    26401 catcaagtcc agtcaaggtg ggaaaatcgg agtgattgga acgcccatga cggtacaatc
    26461 agacatatac cgtcagaaaa tccatgatct ggatcccgac ttacaggtgg agagcttggc
    26521 ctgtcccaag tttgctccct tggttgagtc aggtgccctg tcaaccagtg ttaccaagaa
    26581 ggtggtctat gaaaccctgc gtcccttggt tggaaaggtg gatagcctga ttttgggctg
    26641 tactcattat ccactccttc gccctattat ccaaaatgtg atggggccaa aggttcagct
    26701 catcgatagt ggggcagagt gcgtacggga tatctcagtc ttactcaatt attttgaaat
    26761 caatcgtggt cgcgatgctg gaccactcca tcaccgtttt tacacaacag ccagtagcca
    26821 aagttttgca caaattggtg aagaatggct ggaaaaagag attcatgtgg agcatgtaga
    26881 attatgacaa ataaaattta tgaatataag gatgaccagg actggtatgt tgggtcttat
    26941 agtatttttg gtggcgttaa cagtttgagc gactataaga cagattttcc tctgtttgaa
    27001 ttctccaaaa tatttggaga tgaagagtat ggtttcccgc tttcagttac tgttttacgc
    27061 tatggttcta cctaccgttt gttctccttt gtggtagaca tgcttaatca agaaatggga
    27121 cgaaacttgg aagttattca acgtcatggg gccctgctct tggttgaaaa tgggcaactc
    27181 ttgtatgtag aattgcctaa agaaggggtc aatgttcatg atttctttga gacaagcaag
    27241 gtcagagaaa ccttgttgat tgcgactcgt aacgaaggta aaaccaagga attccgagct
    27301 atctttgata agttaggcta cgatgtggaa aatcttaatg actaccctga cctgcctgaa
    27361 gtagcagaaa caggtatgac ctttgaagaa aatgcccgcc ttaaggcaga aaccatttct
    27421 caattaacgg gcaagatggt tttggcagat gattctggtc tcaaagtcga tgtccttggt
    27481 ggcttaccag gcgtctggtc agctcgtttc gcaggtgtgg gagcaactga ccgtgaaaat
    27541 aatgccaaac tcttgcacga attggccatg gtctttgaac tcaaggaccg ctcggctcag
    27601 ttccacacaa ccctagtcgt agccagccca aataaggaaa gtttagttgt tgaagcagac
    27661 tggtcaggtt atattaactt tgaacctaag ggtgaaaatg gctttggcta tgatcccctc
    27721 ttccttgtag gagaaacagg tgagtcatca gctgaattaa ccctggaaga aaaaaatagt
    27781 caatctcacc gtgccttagc cgttaagaaa cttttggagg tatttccatc atggcaaagc
    27841 aaaccatcat tgtaatgagc gattcccatg gcgatagctt gattgtggaa gaagtccgtg
    27901 atcgctatgt gggcaaagtc gatgccgttt ttcataacgg cgattctgaa ctacgtccgg
    27961 attctccact ttgggagggc atccgcgttg ttaaagggaa catggacttc tacgccggct
    28021 acccagaacg tctggtgact gagcttggtt cgaccaagat tatccaaact catggtcact
    28081 tgtttgacat caatttcaac tttcaaaagt tggactactg ggctcaggag gaagaggccg
    28141 ctatctgcct ctatggtcac ttgcatgtgc caagtgcttg gatggaaggc aagatcctct
    28201 ttctaaatcc aggttctatc agccaaccac gaggtaccat cagagaatgt ctctatgctc
    28261 gtgtggagat tgatgatagt tacttcaaag tggacttttt gacacgagat cacgaggtgt
    28321 atccaggttt gtccaaggag tttagtcgat gattgccaag gagtttgaga ctttcttgtt
    28381 ggggcaggag gaaacttttt tgacccctgc taaaaatcta gctgtgttga ttgataccca
    28441 caatgcggat catgcgaccc tcttgctcag tcagatgacc tatacccgtg ttcccgttgt
    28501 gacagatgaa aaacagtttg ttgggacgat tggactcaga gatattatgg cttatcagat
    28561 ggagcatgac ttgagccaag aaatcatggc ggatacggat atcgttcata tgacaaaaac
    28621 ggacgtagcg gttgtttcgc ctgatttcac cattacggag gtcttgcaca agctagtaga
    28681 tgagtccttc ttaccggttg tggatgcaga gggtattttc caagggatta ttacgcgcaa
    28741 gtccatcctc aaggccgtta atgccctctt gcatgacttt agtaaggaat atgagattcg
    28801 atgccaatga gagacaggat ttcagccttt ttagaggaaa agcagggctt gtctgtcaat
    28861 tccaagcagt cctataagta tgatttggag caatttttag acatggtagg tgagcggatt
    28921 tctgagacca gtctcaagat ttaccaagcc cagctagcca atctaaaaat cagcgcccag
    28981 aagcgaaaga tttcggcctg taaccaattt ctctactttc tctatcaaaa aggagaggtg
    29041 gacagctttt accgcttgga attagccaaa caagctgaaa agaagacgga aaagccagag
    29101 attctatacc tagactcttt ttggcaggaa agcgaccatc cagagggccg cttgctagcg
    29161 ctcttaatcc tagaaatggg gctcttgccc agtgagattt tagccatcaa ggttgcggac
    29221 atcaatctgg attttcaggt gctgcgaatc agcaaggctt cccaacagag gattgtcacc
    29281 attcccacgg ccttgctttc agaattggaa cccttgatgg ggcagaccta tctttttgaa
    29341 agaggagaga aaccctattc tcgtcagtgg gcctttcgtc agttagaatc ttttgtcaag
    29401 gagaaaggtt ttccatcctt atcagctcaa gtcttacgtg aacagtttat tctaagacaa
    29461 atagaaaaca aggtcgattt gtacgaaatt gcaaaaaaat taggattaaa aacagtcctg
    29521 accttagaaa aatatagata atggatatta aattaaaaga ttttgaagga cccctggact
    29581 tactcttgca tctggtttct aagtaccaga tggatatcta cgatgtgccc attacggaag
    29641 tcatcgaaca gtatctagcc tatgtctcaa ccctgcaggc catgcgtctg gaagtgacgg
    29701 gtgagtacat ggtcatggct agtcagctca tgctgattaa gagtcgtaaa ctccttccga
    29761 aggtagcaga agtgacagac ttgggggatg acctggagca ggacctcctc tctcaaatcg
    29821 aagaatatcg caagttcaag ctcttgggtg agcacttgga agccaagcac caagaacggg
    29881 cccagtatta ttccaaagcg ccgacagagt tgatttacga agatgcggag cttgtgcatg
    29941 acaagacgac cattgacctc tttttggctt tttcaaatat cctagccaag aaaaaagagg
    30001 agtttgcaca aaatcacacg actatcttgc gggatgagta taagattgag gacatgatga
    30061 ttatcgtgaa agagtccttg attggacgag atcaattgcg cttgcaggat ttgttcaagg
    30121 aagcccagaa tgtccaagag gtcatcaccc tctttttggc aaccctagag ttaatcaaaa
    30181 cccaggagct gatcctcgtg caagaggaga gtttcggaga tatctatctc atggaaaaga
    30241 aggaagaaag tcaagtgcct caaagctaga cttgatagag aggaaagatg agtactttag
    30301 caaaaataga agcgctcttg tttgtagcgg gtgaagatgg gattcgggtc cgccagttag
    30361 ctgaactcct ctctctgcca ccgacaggca tccagcaaag tttaggaaaa ttagcccaga
    30421 agtatgaaaa ggacccagat tccagtttgg ctttgattga gacaagtggt gcttatagat
    30481 tggtgaccaa gcctcaattt gcagagattt tgaaggaata ctctaaggcg cctatcaacc
    30541 agagcttgtc tcgggctgcc cttgagacct tgtccattat tgcctacaaa cagccgatta
    30601 cgcggataga aattgatgcc atccgtggag ttaactcgag tggagccttg gcaaagttgc
    30661 aggcttttga cctgataaag gaagacggga aaaaggaagt attggggcgc cccaacctct
    30721 atgtgactac ggattatttc ctagattaca tggggataaa ccatttagaa gaattaccag
    30781 tgattgatga gcttgagatt caagcccaag aaagccaatt atttggtgaa aggatagaag
    30841 aagatgagaa tcaataagta tattgcccac gcaggtgtgg ccagtaggag aaaagcagaa
    30901 gagctgatta agcaaggctt ggtgacggtt aacggccaag tggtgcgtga actagcaacc
    30961 actatcaagt caggcgacaa ggtcgaagtt gaaggtcaac ctatctacaa cgaagaaaag
    31021 gtctactatc tgcttaacaa accacgcggt gtgatttcca gtgtgacaga tgataagggt
    31081 cgcaagacgg ttgtcgacct cttgcccaat gtcaaagagc gtatttaccc tgtgggtcgt
    31141 ttggactggg atacatcagg tgtcttgatt ttgaccaatg atggggactt tacagacgag
    31201 atgattcacc ctcgtaatga gattgacaag gtttatgtcg cgcgtgttaa aggtgtggcc
    31261 aataaggaca atctccgccc cttgacccgt ggtcttgaga ttgatggtaa gaaaaccaag
    31321 ccagctgttt atgaaattct caaagtggac ccagtcaaaa atcgctctgt ggtgcagttg
    31381 accatccatg aagggcgtaa ccatcaggtt aaaaagatgt ttgaagctgt tggtctccaa
    31441 gtagataagt tgtctcggac tcgtttcgga cacctagact tgacaggact ccgtccagga
    31501 gaatcccgtc gtcttaataa aaaagaaatc agccaactac acaccatggc tgtaactaaa
    31561 aaataatgaa acgaatttta atagcgcctg tgcgctttta ccaacgtttt atctcaccag
    31621 tctttccacc ctcttgtcgc tttgagctga cttgttccaa ctacatgatt caggctattg
    31681 aaaaacatgg ttttaagggg gtattgatgg gcttggctcg gattttacgt tgtcatccct
    31741 ggtcgaaaac aggtaaggat cccgttccag accacttttc ccttaaacga aatcaagaag
    31801 gggaatgagg tggggtaaat agatttcaaa atgataaaaa cgcatcctat caggtttgag
    31861 tgaacttgat aggatgcgtt ttagaatgtc aaaattttat actcttcgaa aatctcttca
    31921 aaccgcatca gctttcatct gcaacctcaa aacagtgttt tgagcaacct gcggctagtt
    31981 tcctagtttg ctctttgatt ttcattgagt attaaattga gtttgaagtg gcttatttca
    32041 aagctttttg tatgtcttca atcatgagtt ttgttgattc aagtccgcct ccgcttagat
    32101 accagaggtc tggtgttagt tggataatct taccattttt agcagcaggt gtttcagcga
    32161 taagggcatt ttctaggaca ccgtcgttgc tagagttgtc cccaccgatg gcaagggtac
    32221 ggttgatgac aaagaggatg tcagggttga tttctttgac actttcaaag ctgacttctt
    32281 gtccgtggcg tgagtcttca aattttgtat cagttggttt gaatttcaag gtttggtaca
    32341 agaaagagaa acgagatttg gcaccaaagg ctgccatttt tccttcatta aggaggatcg
    32401 caagggcttt tttgtcagag ctttcatttt tagtagcgac ttcttggatg ctcttgtcta
    32461 gcttggccaa ttcttccttg gctttttgta tactagtttc gccgaaggca cttgctaagg
    32521 attcgatatt agccttgata gaagtccagt agtcgtcctt gcttgcttgg aagagaacgg
    32581 ttggggcgat ttctttgaat ttgtctacga atttttgtgt acgtggtgaa gcgataatca
    32641 aatcaggctc aagggcggcg atagcttcta aatcaggttc tttcatagaa ccaacatttt
    32701 tgacagttcc cactaggtct tttagataag tcggaatagt ttttgtaggc attccgatga
    32761 tatttttttc aaatcctaaa gcgcgaatag tatccgcagc gccgaggtca aaggtcacaa
    32821 tcttttcagg aactttggaa agtttgacct cgtccagtga acttttaatg gttacctctg
    32881 ttggagcaga gctactggtc tctgtctgac tagtgcttga gtttgtacta catgcaccaa
    32941 gtaggagcaa gaagctggcc actagggcag tgaaataaag tttaagggat gttttcataa
    33001 tttctccttt ttaaaatgtg ataacgattt agggagtctc ttaatcttat tgactaagag
    33061 actgaaggtt ctctaacttg agcttttatg ttactagcta tagatacaga tctttttgtc
    33121 attgatatca gctagcgtga tgggaatctc ataaagttga ctgagcaggt cagcctgcat
    33181 gatttgatcg gttcttccct tgctaaagac ctggccgtcc ttgaaggcga caatttcatc
    33241 tgcatactga ctggccatgt tgatatcgtg gaggacgatg ataatggtct tgccgagttc
    33301 ctccaccagt cgtcgaagaa tctgcatcat gctgacgctt tgcttgatat cgagattgtt
    33361 gagtggttcg tccagcaaga taaagtccgt atcctgggcc agtaccatag cgataaagac
    33421 gcgctggagt tgcccccctg acaggctatt gatgtagcgg tcttttaagt tggtcagttc
    33481 caaatagttc agagtttctc ggattttttc ccagtcttct gatctaagtc gacctcggct
    33541 gtagggaaaa cgtccaaaac tgaccagttc ttcaacagtc aatttggctt ggtaattgat
    33601 tttctgtttt aggatggtta gttcttgggc cagttcttgc gaattccagc tctcgatttc
    33661 acgtcctttg atactgagaa ctccctgatc tttcttggtt agtctgctca tgatggagag
    33721 gagagtcgat tttccagcac catttggacc aataaaggct gtcagttttt gaggactgac
    33781 ttcaagcgaa atgccttgca aaatatcctg tttttgaatg gatttgtcaa tgttttccag
    33841 tttcactgac gagacctcct atatagtaag ataaagaata agaagccacc cacactctca
    33901 atgatcatac tgatacgaat ttccagtgca aagactcgtt caatcaaggc ttgccccaag
    33961 gttaagctaa taaatccaac cagaatggcc actataaaga gtaacttgtg ctgatagtct
    34021 ttgacaatca ggtaggtgag gttagccagc ataaagccga agaaggccat aggtcctacc
    34081 aaggcagtgg ccgttgaggt caaaagcacg attccccaga ggagctcttt ctgttctttt
    34141 tcaacatcga gtcccaatat ctgagccgtt tctctttgca ggtgcaagac atctagaacg
    34201 actgcttttc gaaagaaaaa gattgtcaaa gcgaggatga tcagagaacc gatggctagg
    34261 atggaagtgt tgagatgttg aaaggaggca aaaagactat tttgcagttt atcgtattcg
    34321 tttggatcca ttaggacttg aaggaaggtg ctaatatttc gaaagagact tctgagcgct
    34381 agacagatca gcaggatgaa gaccaggtct tgcttcatca gtgtcttcaa gtaaccttgt
    34441 aaggcgagaa agaagaagga ctggacaaga agtaagacta ggaattctaa gataggggat
    34501 ttgccaagtt gaagaaactt gctttcaaaa accagtagta gggtttgtag taggacgtag
    34561 aaggattcaa ttcccaaaat actaggcgtc aggaagcgat tttccgtcag ggtttgaaaa
    34621 ctaatggtcg aaatcccagt cgcgatggct accaagagat aaacgatgat cttttgggaa
    34681 cgcaacttcc aagcaaaggc tgacaagtga gtgatgggcc aaaagtagag aagacaagct
    34741 ccgatggcaa gaataatgag aatccagaag agcttggtat gtttgctttt agtctgcatc
    34801 ttttcgtccc cctctccaga gaagtaggat aaagacgaga ctaccgatga ttcctagcaa
    34861 gagactgaca gacaactcat agggcctaat cagaactcgg gataggatat cgcaagccag
    34921 aactagattg gcaccaacca gtgcgaccat gagtttggtt tgacttagat tatctccata
    34981 gcgcttgcga acaagattgg gaacgataac tccgagaaat ggtaagccac ccacggtaat
    35041 catggtgacg cttgtcgtta gcgccaccag aaagagggcc agtttttcaa gtagggagta
    35101 ggaaatcccc aaactctcgc tggtttcttt ccccagattc atgatggtga aggtttggga
    35161 taatttccaa acggttatca ggatgatgag gcctaagaag agccactcat actgatgggt
    35221 ctgaatcatg gagaaggagc cctgggtcca ggcagtcata ctctgaacca gattgaaacg
    35281 ataggcgata acttctgtga ctgagccgat aatcccgcta tagatgatcc caatcagagg
    35341 caacatccac ctttccttta cagtaaaaat ggtcataaag gctaggaaga agagggtgaa
    35401 tacgatggat gaaacaaaag cgaagagcat cttttgggtc agactagccg atggaaagac
    35461 aaaaaggctc agcaccattc ccagtttggc ggcttcagtc gttccaactg tactcggtgc
    35521 agcaaactga ttttgggtaa tagtctgcat gagaaggcct gccatactca tactagaggc
    35581 agtcaggaga atactgatag ttcttgggag acgggactct tgaaagagga gccaggtctg
    35641 ctggtcgaaa tcaaatagct ttccccatga aaaatcactg gtcccaatgc taatagagag
    35701 aaagactagg agtagaagta agccaattaa ataatgagaa agtttcatac cccgtccttt
    35761 catgtagatt tggtatcgaa agatatctgc ggatataaat gtaacattat ttttctaatc
    35821 tgtcaataaa atttctgaca atttaataaa tacaacaagg agagagcaac aagactttct
    35881 cctttgttat cctattctaa aatgttttta ccttaatctg ataaaataat atcttcgagg
    35941 gagtagctag ccgtccaatc aagatattgt ttagcttttg aagcatctgc taggacactg
    36001 gctgggtcac tagcacgtcg agcaacaatc tcgtgtggga ttttttaatt tagtaattct
    36061 tcagcagttt taaagatttc tttgatagta tagccttttt tagtttctaa gttaaagatt
    36121 tgagaagaac tgtcttcttg aaataggtag ttcattcctt taacatgagc ctatgcaagg
    36181 tccaagacat aaatgtaatc tcgaatacat gaaccgtcac gtgtatcgta gtcatctcca
    36241 aatattttta agctatcatt ttgtcccaat gcggtcttgt tgatatttgg aatgatgtga
    36301 gttggatttt tcacacgcag accgtttgaa gcatccattt cagccccagc agcattaaag
    36361 taacggaaaa taacatattt ccagtcgtag cgattggcca tccagtaaat cattcgttcg
    36421 cccatcagtt ttgtctctgc ataagggttg acagggtcga gcagggtatc ttcagtcacc
    36481 ggcttgtcaa tacagttatt tccatagaga gaagcagtcg aagagaacat gattttttga
    36541 atgccaactt cagataagac tttgagaact tggttcatac cagcaacgtt ggcagtgaag
    36601 tatttacttg gattttcaat actttcgctc acaacagttt cacctgcaca atggagggca
    36661 gcatcaatct gattttcttc taagtaagac tttaaggcgc tagcatcata aacatccagt
    36721 tctttaaagc tagcacgact atccacagcc gctcgatttc ctgtagagag attatcgagg
    36781 acatgcacct gatagccagc atttaaaaga gctttaacgg tatgggagcc aatgtagcca
    36841 gtctcacctg taacaagaat tgttttggtc atgatttttt ccttttctag ttttgtacta
    36901 tagtagattg aaataagata tgaataactc tattaggaaa gtcaaattaa tttctagaaa
    36961 tgttttagca gctacagcgt actattccaa actcaaccaa ctataataga tcgaaactag
    37021 aatagtacac atctacttct aaaacattgt taaaaatcga tttgactttc cttatttcat
    37081 tccgctatat ataagtttgc tgtttcttgt cgctcctctg gaaagctgat ataatagctt
    37141 tatgaataaa aaacgaacag tggacctgat acatggtccg attcttccct cgctcttaag
    37201 cttcaccttt ccaatcttgc tatcaaatat ttttcaacag ctctataaca ctgctgatgt
    37261 cttgattgtt ggacgatttc ttggtcaaga atccttggct gcagtaggag cgacgacagc
    37321 gatttttgac ctgattgtag gttttacact tggtgttggc aatggcatgg ggattgtcat
    37381 tgctcgttat tatggggctc ggaatttcac taaaatcaag gaagcagtag cagccacctg
    37441 gattttaggt gctcttttga gcattctagt tatgttgctg ggctttcttg gcttgtatcc
    37501 tctcttgcaa tacttagata ctcctgcaga aattcttcct caatcttatc aatatatttc
    37561 tatgattgtg acctgtgtag gtgtcagctt tgcttataat ctttttgcag gcttgttgcg
    37621 gtctattggt gacagtctag cagccctggg atttctgatt ttctctgcct tggttaatgt
    37681 ggttctggat ctctatttta ttacgcaatt gcatctggga gttcaatccg caggacttgc
    37741 tactattatt tcacaaggtt tatcagcggt tctctgcttt tattatattc gtaaaagtgt
    37801 gccagaactc ttgccacggt ttaaacattt caaatgggac aaaagcttgt acgcggatct
    37861 cttggagcaa ggtttggcta tgggcttgat gagttcaatt gtatctatcg gcagtgtgat
    37921 tttacagtct tctgttaata catttggtgc agtgattatt agtgctcaga cggcagctcg
    37981 acgcattatg acctttgccc ttcttcctat gaccgctatt tctgcatcaa tgacgacctt
    38041 tgcttctcag agtctaggag ctaagcgacc tgaccgcatt gctcaaggtc ttcgaatcgg
    38101 cagtcgttta agtatatcct gggcagtttt tgtttgtatt ttcctctttt ttgccagtcc
    38161 agccttggtt tccttcttgg ctagttcgac agatggttac ttgatagaaa atggaagtct
    38221 ctatctgcaa atcagttcag ccttttatcc cattttgagc ctcttgttga tttatcgcaa
    38281 ttgcttgcag ggcttggggc aaaagatcct tcctctagtt tctagcttta ttgaactaat
    38341 cggaaaaatc gtttttgtgg ttttgattat tccttgggca ggatataagg gtgttatcct
    38401 ttgtgaacct cttatctggg ttgccatgac agttcaactg tacttctcac tattccgtca
    38461 tcccttgata aaagaaggaa aggcaatttt ggcaaccaaa gtgcaatcct agttggattt
    38521 actgaataaa atccatttcc tctagtgaac atcgaaaaaa cttgtgttct cttctttagt
    38581 ttggtgttga aaatagttta acagactttt gacttctttt atatgatata ataaagtata
    38641 gtatttatga aaaggacata tagagactgt aaaaatatac ttttgaaaag ctttttagtc
    38701 tggggtgtta ttgtagatag aatgcagacc ttgtcagtcc tatttacagt gtcaaaatag
    38761 tgcgttttga ggttctatct acaagcctaa tcgtgactaa gattgtcttc tttgtaaggt
    38821 agaaataaag gagtttctgg ttctggattg taaaaaatga gttgttttaa ttgataagga
    38881 gtagaatatg gaaattaatg tgagtaaatt aagaacagat ttgcctcaag tcggcgtgca
    38941 accatatagg caagtacacg cacactcaac tgggaatccg cattcaaccg tacagaatga
    39001 agcggattat cactggcgga aagacccaga attaggtttt ttctcgcaca ttgttgggaa
    39061 cggttgcatc atgcaggtag gacctgttga taatggtgcc tgggacgttg ggggcggttg
    39121 gaatgctgag acctatgcag cggttgaact gattgaaagc cattcaacta aagaagagtt
    39181 catgacggac taccgccttt atatcgaact cttacgcaat ctagcagatg aagcaggttt
    39241 gccgaaaacg cttgatacag ggagcttagc tggaattaaa acgcacgagt attgcacgaa
    39301 taaccaacca aacaaccact cagaccatgt ggatccatac ccttacttgg caaaatgggg
    39361 cattagccgt gagcagttta agcatgatat tgagaacggc ttgacgattg aaacaggctg
    39421 gcagaagaat gacactggct actggtacgt acattcagac ggctcttatc caaaagacaa
    39481 gtttgagaaa atcaatggca cttggtacta ctttgacagt tcaggctata tgcttgcaga
    39541 ccgctggagg aagcacacag acggcaactg gtactggttc gacaactcag gcgaaatggc
    39601 tacaggctgg aagaaaatcg ctgagaagtg gtactatttt gatgtagaag gtgccatgaa
    39661 gacaggctgg gtcaagtaca aggacacttg gtactactta gacgctaaag aaggcgccat
    39721 ggtatcaaat gcctttatcc agtcagcgga cggaacaggc tggtactacc tcaaaccaga
    39781 cggaacactg gcagataaac cagagttcac agtagagcca gatggcttga ttacagtaaa
    39841 ataataatgg aatgtctttc aaatcagaac agcgcatatt attaggtctt gaaaaagctt
    39901 aatagtatgc gttttcttgt ggagatattt ccttcaatgt ttgctactat attaaacaaa
    39961 aatcagaaag cgaactagaa agttatgctc aaataaaatc taaatttgac aatgtaaacc
    40021 gagtcggata gctttaagta ctgttttgag gttgaagata cgatttttga taggaactca
    40081 tcaattttag atttttaagc agcatcaata aattgcttcc ttgttttgtc ataatttttt
    40141 tatttaaaaa attatgacaa gagtgtgcta ttctttttat gagaggtgta tgaatatgat
    40201 aaatgtatgt gatgttggaa aaagaataaa agaacttaga atatcttcaa atcttactca
    40261 agataagatt gctgagtatt tgtctttgaa tcaaagcatg attgccaaaa tggaaaaagg
    40321 tgaaaggaat atcacgaatg gatttaagta ataaagcttc aaatcttaga aaaaagttgg
    40381 gagctgatgg tgaatcgtcg atagatattt ttaaattggt acaaaagata gaaaatttga
    40441 cgctggtatt ttatggactc ggaaagaata ttagcggagt ctgttataaa ggaactcagt
    40501 tcagtctcat tgcagtcaat tcagacatgc cattaggaag gtaaagattt tctttagcac
    40561 atggactgta tcatctttat tatgatgagg tgaagaagag ttcagtcagt cttatcttga
    40621 ttggtgaagg agatgaaact gaaagaaaag cggatcagtt tgcttcttat tttttaattt
    40681 tcccatcttc actgtatagg atggttgagg aaatcagaga aaatgccaat agaactcatc
    40741 ttgaagtaga agatattata aaattgggtc agttttatgg tatcagtcat aaagctatgt
    40801 tatatagatt gagaaatgat ggataccttg atgcagaaga aattaaaaat atggatatta
    40861 gtgttataga gacagcttca agattaggct atgatacaag tttatatcgt cctttgtcag
    40921 aaagtaaaaa ggaaatggta ttaggacact atattaaatc gactgaacaa cttttagaaa
    40981 ataacagaat ttcgcaaggg aagtatgagg aactgttact agatgctttc agatatgata
    41041 ttgtatatgg gctagatgaa gagggggagt tgtcgtttga ctagtcgtgt atttattgat
    41101 gcagattgta tttcagcatt tttatgggtt ggcactgaac atcttttaga aaagctctat
    41161 tcgggtaaaa ttgttattcc acaagaggtg tatgatgaaa tcaatatacc tacaattccc
    41221 catttaaaat ctaggataga ccagttggta actaagggtt cagctgagat tgtgagcata
    41281 gacattggaa ctgaagaata cgcattatat agagatttaa caagaaatca tgatagtaac
    41341 aagattattg gtaagggaga agcgacttct attttcttag cgaaaaagca taatgggata
    41401 ttaggaagta ataacctaag agatgttaaa ccatatgtag aagaattttc tttagaacat
    41461 atgacaacag gagatatact gattgaagcg tttaaagcgt aatttattac tgaacaagag
    41521 ggcaatcata tctggaataa tatgcttaaa aagagaagga aaattggtgc aaattcattt
    41581 tcagactatc ttcgtggaag tattcatcaa aatagacaaa aataaatttg gataaatcga
    41641 actcactatt caggaggcat atgagcaatt cgaaaaagaa aagtgtcaaa ttgagcctat
    41701 aggagtagaa gtgaaatagt aagtcctgca tagtggatga gagaaaagtt ctccttgaag
    41761 ttttcctgaa ctatcagtcg catgtcaaac gatatgtagg gtaatgtgag aggggatagc
    41821 gagtagtttt tggttatttt atcaaaaaac ttatatttta ttataccgaa tgataaaata
    41881 taataaaaat gatagaataa ggaaaaaaca tgaatgtcaa aaagataatg tcaatttttc
    41941 aatcctttta tgttgatgtc agtattgagg aactgacttt gactttacca atcagttttg
    42001 taaaaaggtt tgagtatact caaatgactt ttcataagga atcattttta ttgattaaag
    42061 aaaagagaag ggggagtttg agttcatttg ttactcaggc tcgcactatg ggtgaaaaag
    42121 ccaatatgga tgttgttttg gtgttttcga agttatcaga cagtgaaaaa aagcaattac
    42181 ttcaagctag agttccgttt gtagacttta agggaaacct cttcttccct ccattgggac
    42241 tagtactcaa tgcgaatgat actgaaatcc ctaaggaatt aacacctagc gaacaattaa
    42301 cgtggattgc ctttttattg ccagatggcg atataaagca gataaaatct gtttctaacc
    42361 ttctatatgg tggtgcttat gctttgtcgc attcaacttt tttagctgaa acggatgaaa
    42421 atactagcta tgtcatatgg cagagaaaat tcaatcagtt atccttgcca ctttctcagc
    42481 atgttttaaa aggaaagatg ctagagatat ggaaatatcg tccttttgta tctgagtttt
    42541 ggaatgattt taaaaataat catgataaac aatttgtaga tccgatttct ctttatttga
    42601 ccttaaaaga tgatgatgac ccacgtatag aggaagagag tgaagcacta gaaaatatga
    42661 tattacagta tctgggagaa gatgatgcca gctaatacga aagttatttt tcaagaaatg
    42721 tttgcggatt ttcagaacta ttatgttctg attgggggaa ctgctacctc tatcgtattg
    42781 gattcgcaag gatttaaaag tcgcacaata aaagattatg atatggtcat catttatgaa
    42841 gtaaaaaata aggaatttta tactaccttg aatcattttt tagaattggg agagtatcaa
    42901 ggaagtcaga aagatgagaa agcgcagctt tttcgattta caacaactaa tcctgagttt
    42961 ccttctatga ttgaactatt tagtatctta ccagaatatc cattaaagaa ggacggtcga
    43021 gaaattccct tacattttga ccaagatgcc agtttatcag ccttattatt ggatgaagat
    43081 tattataata tattggtgca tgaaaaagaa accattcagg ggtattcggt attgagtaat
    43141 tgtggtttat actcttcgaa aatctcttca aaccacgtca gcttccatct acaacctc
//
LOCUS       DBEJZJ010000017        36791 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000017 DBEJZJ010000000
VERSION     DBEJZJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.17"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            366..1442
                     /locus_tag="ACL3R8_001143"
     CDS             366..1442
                     /locus_tag="ACL3R8_001143"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR1314024.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIVACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            1498..2433
                     /gene="dapA"
                     /locus_tag="ACL3R8_001144"
     CDS             1498..2433
                     /gene="dapA"
                     /locus_tag="ACL3R8_001144"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR1314025.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(2480..3853)
                     /gene="mnmE"
                     /locus_tag="ACL3R8_001145"
     CDS             complement(2480..3853)
                     /gene="mnmE"
                     /locus_tag="ACL3R8_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR1314026.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAAKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEEVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(3990..4172)
                     /locus_tag="ACL3R8_001146"
     CDS             complement(3990..4172)
                     /locus_tag="ACL3R8_001146"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR1314027.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            4295..4894
                     /locus_tag="ACL3R8_001147"
     CDS             4295..4894
                     /locus_tag="ACL3R8_001147"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR1314028.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            4884..5363
                     /locus_tag="ACL3R8_001148"
     CDS             4884..5363
                     /locus_tag="ACL3R8_001148"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1314029.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            5373..6452
                     /gene="prfA"
                     /locus_tag="ACL3R8_001149"
     CDS             5373..6452
                     /gene="prfA"
                     /locus_tag="ACL3R8_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR1314030.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            6452..7291
                     /gene="prmC"
                     /locus_tag="ACL3R8_001150"
     CDS             6452..7291
                     /gene="prmC"
                     /locus_tag="ACL3R8_001150"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR1314031.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            7278..7877
                     /locus_tag="ACL3R8_001151"
     CDS             7278..7877
                     /locus_tag="ACL3R8_001151"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR1314032.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            7879..8310
                     /locus_tag="ACL3R8_001152"
     CDS             7879..8310
                     /locus_tag="ACL3R8_001152"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1314033.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            8372..9628
                     /gene="glyA"
                     /locus_tag="ACL3R8_001153"
     CDS             8372..9628
                     /gene="glyA"
                     /locus_tag="ACL3R8_001153"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR1314034.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            9636..10610
                     /locus_tag="ACL3R8_001154"
     CDS             9636..10610
                     /locus_tag="ACL3R8_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR1314035.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            10610..11224
                     /gene="pmp23"
                     /locus_tag="ACL3R8_001155"
     CDS             10610..11224
                     /gene="pmp23"
                     /locus_tag="ACL3R8_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR1314036.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            11298..12272
                     /locus_tag="ACL3R8_001156"
     CDS             11298..12272
                     /locus_tag="ACL3R8_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR1314037.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            12346..13977
                     /gene="rlmD"
                     /locus_tag="ACL3R8_001157"
     CDS             12346..13977
                     /gene="rlmD"
                     /locus_tag="ACL3R8_001157"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR1314038.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            14715..14933
                     /locus_tag="ACL3R8_001158"
     CDS             14715..14933
                     /locus_tag="ACL3R8_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1314039.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            14937..15206
                     /locus_tag="ACL3R8_001159"
     CDS             14937..15206
                     /locus_tag="ACL3R8_001159"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314040.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFIDELMKNIDII"
     gene            15327..16352
                     /locus_tag="ACL3R8_001160"
     CDS             15327..16352
                     /locus_tag="ACL3R8_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR1314041.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            16342..17349
                     /locus_tag="ACL3R8_001161"
     CDS             16342..17349
                     /locus_tag="ACL3R8_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR1314042.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            17349..18356
                     /locus_tag="ACL3R8_001162"
     CDS             17349..18356
                     /locus_tag="ACL3R8_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR1314043.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFAKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            18356..19150
                     /locus_tag="ACL3R8_001163"
     CDS             18356..19150
                     /locus_tag="ACL3R8_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314044.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            19301..19485
                     /locus_tag="ACL3R8_001164"
                     /pseudo
     CDS             19301..19485
                     /locus_tag="ACL3R8_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            19538..19963
                     /locus_tag="ACL3R8_001165"
     CDS             19538..19963
                     /locus_tag="ACL3R8_001165"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1314045.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            20019..20336
                     /locus_tag="ACL3R8_001166"
     CDS             20019..20336
                     /locus_tag="ACL3R8_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGR1314046.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            20646..22286
                     /gene="mobQ"
                     /locus_tag="ACL3R8_001167"
     CDS             20646..22286
                     /gene="mobQ"
                     /locus_tag="ACL3R8_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HGR1314047.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEK
                     KILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKVVSGKLKKLLSDKEKLS
                     PKKWNEEKILLMSNLEEINKEKDKIKDEYQEINHIKYSVDFVNKELGIDLSIEIDKLI
                     KQGEKPSVIAQIKKFQDQVNKDNEYREMMKNKKMDQER"
     gene            22360..22533
                     /locus_tag="ACL3R8_001168"
     CDS             22360..22533
                     /locus_tag="ACL3R8_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314048.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            22719..23246
                     /locus_tag="ACL3R8_001169"
     CDS             22719..23246
                     /locus_tag="ACL3R8_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGR1314049.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            23373..24101
                     /locus_tag="ACL3R8_001170"
     CDS             23373..24101
                     /locus_tag="ACL3R8_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR1314050.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            24785..24946
                     /locus_tag="ACL3R8_001171"
     CDS             24785..24946
                     /locus_tag="ACL3R8_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314051.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            25038..26717
                     /locus_tag="ACL3R8_001172"
     CDS             25038..26717
                     /locus_tag="ACL3R8_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR1314052.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            26985..27551
                     /locus_tag="ACL3R8_001173"
     CDS             26985..27551
                     /locus_tag="ACL3R8_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314053.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            27872..28060
                     /locus_tag="ACL3R8_001174"
     CDS             27872..28060
                     /locus_tag="ACL3R8_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR1314054.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            28122..28880
                     /locus_tag="ACL3R8_001175"
     CDS             28122..28880
                     /locus_tag="ACL3R8_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR1314055.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            28938..29792
                     /locus_tag="ACL3R8_001176"
     CDS             28938..29792
                     /locus_tag="ACL3R8_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR1314056.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            29904..30788
                     /locus_tag="ACL3R8_001177"
     CDS             29904..30788
                     /locus_tag="ACL3R8_001177"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR1314057.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            30951..32030
                     /locus_tag="ACL3R8_001178"
                     /pseudo
     CDS             30951..32030
                     /locus_tag="ACL3R8_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            32024..33360
                     /locus_tag="ACL3R8_001179"
                     /pseudo
     CDS             32024..33360
                     /locus_tag="ACL3R8_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(33401..34252)
                     /locus_tag="ACL3R8_001180"
     CDS             complement(33401..34252)
                     /locus_tag="ACL3R8_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HGR1314058.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLIQYIRKQYSLQNINNIQSLLSDS
                     SNYTLDSFEKTMVKSILHTMDSRIIPSDDELLQLADYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCFILSIDKEEFSNCSYLINEIK
                     GLLENELNFYEQTVFLYATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
     gene            34334..34405
                     /locus_tag="ACL3R8_001181"
     CDS             34334..34405
                     /locus_tag="ACL3R8_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGR1314059.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            34509..35378
                     /locus_tag="ACL3R8_001182"
     CDS             34509..35378
                     /locus_tag="ACL3R8_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HGR1314060.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            35365..36087
                     /locus_tag="ACL3R8_001183"
     CDS             35365..36087
                     /locus_tag="ACL3R8_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR1314061.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            36160..36615
                     /locus_tag="ACL3R8_001184"
     CDS             36160..36615
                     /locus_tag="ACL3R8_001184"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314062.1"
                     /translation="MIVLYDSFDSIVNCFDKLKGQYILLPVAFESSIKNYSWKDFNFE
                     YHKRIEIVDSFHSFTKGMVLIENCNYKINRAIIQPATEILMLNYLKKKSMDLRIDFTH
                     SKVMANKKFLEEGYRFSIVSQETIINNDDIIICETFSPEMIWCLYRVKG"
BASE COUNT        13172 a         5685 c         7214 g        10720 t
ORIGIN      
        1 aaactgacga agtcagtaac catacatacg gcaaggcgac gctgacgaag tttgaagaga
       61 ttttcgaaga gtataaagag tttcgtctgt tgacaaaagt cattctcttt agtagaatag
      121 tagatgcgat gagtcgatag gtagtcttcg ggctactatt gagcataagg aggtcataac
      181 gcaggagcgg accttgatga gttgtgtgaa cctgctcatc acatgaagat gcctcttaat
      241 ccctagtcta gcgattgggg atttttattt tccaaaaaat gatgaaaaag ctttgcaatt
      301 catggaaaaa gtagtataat acttctatta tagaaatttt tagaaaattc cgaaagaggt
      361 tatttatggg atatacagtt gctgtagtcg gcgcgacagg tgctgtcggt gctcagatga
      421 taaaaatgtt ggaagaatca acacttccaa tcgataaaat ccgttacctt gcttctgcac
      481 gttcagcagg taagtcattg aaatttaaag atcaagatat tacgattgaa gaaacgactg
      541 aaacagcttt tgaaggagtt gatattgctc tcttttcagc aggtggttct acatcagcta
      601 agtatgcacc atacgcagta aaagctggcg tggtagtagt agataataca tcttatttcc
      661 gtcaaaatcc agatgttcct ttggttgttc cagaggtcaa tgctcatgca cttgatgctc
      721 acaacggaat cgttgcctgc cctaattgtt caacaatcca aatgatggtg gctcttgagc
      781 cggttcgcca aaaatggggc ttggaccgta tcattgtttc aacttatcaa gccgtttcag
      841 gtgctggtat gggagcaatt cttgagacac aacgtgaact tcgtgaagtc ttgaatgatg
      901 gtgtgaaacc atgtgatttg catgcggaaa ttttgccttc aggtggtgac aagaaacatt
      961 atcctatcgc ctttaacgct cttccacaaa ttgatgtttt cactgataat gattacacgt
     1021 acgaagagat gaagatgacc aaggaaacta agaaaattat ggaagatgat agcattgcag
     1081 tatctgcaac atgtgtgcgt attccagtct tgtcagctca ctctgagtct gtttatatcg
     1141 aaacaaaaga agtggctcca atcgaagaag taaaagcagc tatcgcagcc ttcccaggtg
     1201 ctgttcttga agatgatgta gctcatcaaa tctatcctca agccatcaat gcagttggtt
     1261 cgcgtgatac ctttgttggt cgtatccgta aagacttgga tgcagaaaaa ggaattcaca
     1321 tgtgggttgt ttcagataac cttctcaaag gtgctgcttg gaactcagtt cagattgctg
     1381 aaactcttca tgaacgtgga ttggttcgtc caacagccga attgaaattt gaattaaaat
     1441 agtcatatcg tttaggagtt cagatgaact ccttctttga aatagagagg tgttttcgtg
     1501 tcttatcaag atttaaaaga atgtaaaatc attacagcct ttattacccc cttccatgag
     1561 gatggttcca ttaactttga tgctattcca gccttgattg agcatttatt ggcccatcat
     1621 acggatggaa ttcttctcgc aggaacgact gctgagagtc caactttgac ccacgatgag
     1681 gagttggagt tgtttgcggc tgtacaaaag gttgtcaatg gacgcgttcc tttgattgcg
     1741 ggtgtaggta ctaatgatac gcgtgactct attgagtttg tcaaagaagt agcggaattt
     1801 ggtggtttcg cagctgggct tgctattgtt ccttactaca acaaaccttc tcaagaaggg
     1861 atgtatcagc actttaaggc tattgcagat gcttctgacc taccaattat tatctataac
     1921 attccagggc gtgtagttgt cgaattgact ccagaaacca tgcttcgctt ggctgactat
     1981 ccaaatatta tcggtgtcaa agaatgtact agcttggcta atatggctta tttgattgag
     2041 cacaagcctg aagagttctt gatttataca ggtgaggatg gagatgcttt ccatgccatg
     2101 aaccttgggg cggatggggt tatttctgtt gcctctcata caaatgggga tgaaatgcac
     2161 gagatgttta ctgccattgc agaaagcgat atgaagaaag ccgcagcaat tcagcgtaaa
     2221 ttcattccta aggttaatgc tctcttctct tatccaagtc ctgctccagt taaggcagtt
     2281 cttaactata tgggatttga agctggaccc actcgtctac ctcttgttcc agcaccagaa
     2341 gaagatgcca aacgcattat caaggttgtc gtagatggcg actacgaagc aactaaggca
     2401 actgtaacag gggtcttaag accagattac taataaagac aataaaatcc atgaccgaat
     2461 gaaggatcat ggatttttct tattttccta aacagaattg gctaaagagt tgggtaataa
     2521 gttcatctgg agcagcatcc ccagtgattt ctccgaggat ttcccaagta cgagtcaagt
     2581 caacttgaag caaatcaact ggcatcccca gctcaagacc ttgattaacg gcttgtaggc
     2641 tttcaactgc tttttcaatc agggaaatgt gacgggcgtt tgacaagtag gtagcatctt
     2701 gctcgaccaa gccagcattt tcaaagaaga ggttgttgat tcgctcttca atcttgtcga
     2761 tgttttggtt tttaaggact gaaatacgga taacctcttc aggtagtttc gaagtttcaa
     2821 tcgtttctgg caggtcggtt ttattaagta gaataatgcg attggtatct tggctaattt
     2881 caagaagttg tctgtcttgc gcagtcagtg gttcactggc atttagcact agtagaacca
     2941 agtcggcttc cttgagggct tttttcgaac gctcaacacc gatttgttcc actatgtcat
     3001 ctgtttcacg aataccggct gtatcaatca atttgagagg tacaccattg atgttgacgt
     3061 actcttcgat gacatctcgt gttgtcccag cgatatctgt tacgatagcc ttgtcctcac
     3121 gcaagaggtt gttgagaagg cttgatttcc caacgttggg acgtccaatg atagccgttg
     3181 aaattccttc acgaaggatt ttgccgcgac gggctgtcct aaggagcttg gttagcaatt
     3241 gctcaaactc catagtcttc tcacggacaa cagcagtagt agcttcctca acatcatcat
     3301 attcaggata gtcgatattg acctcaactt gggcaagtgt attgaggatt tcttgacggg
     3361 tattgttaat gaggtcagaa agggagccgt ctaattgctt agctgcaatg ttcatggcct
     3421 tgtcagtctt ggcacggatg atgtccatca ctgcctcagc ctgtgtcaaa tctacgcgac
     3481 cgtttaggaa ggcacgtttg gtaaattcac caggttcagc caatcgagct ccttcacgga
     3541 tagctagctg gagaatctca ttggtcaccg caatcccacc gtgggtgtta atctcgataa
     3601 tatcttcacg agtgaaggtt tttggagatt tcatggctcc taccatgacc tcgtccatga
     3661 ctttaccagt cagaggatca ataatgtgac cgtagttgag agtgtggctg gcaaccttgt
     3721 tcaagtcttt tcctttaaaa atcttttgcg caatagcaaa actgtctgtt ccgctcaggc
     3781 ggacaatacc aatagcccct tcacctagtg gagtagagat agcagcgatg gtatcaaatt
     3841 cacgtgtaat cataatgttt cctttaatta atagctattt tcttggaaat tctccaagtt
     3901 tcttttcaaa ttgtaacaaa tttaggatat ttcttcaatg aatgctactt ggagattgaa
     3961 aaagcctaag caattctgct taagctagct tatttagtac gcatttcccc ttgtgggaag
     4021 taagttcctt ctggcatgtc gttgatgatg acatggacag cagattgagg ggctccagtg
     4081 ttgcggacaa ctgcttccgt tacttcctta gcaagagctt tcttttgctc gagcgtgcgt
     4141 ccttcaaata aatcgatgcg tacaaatggc ataatagctt cctccactag ttttgatttc
     4201 ttccatttta ccacattttg ccgtttaaag cttaagaaaa ttatgatata ctagaatgta
     4261 gcaaaaattt agaaatggac gtgaagcaag aaacatggca cagttgtatt atcgttatgg
     4321 gaccatgaac tctggtaaaa cgattgagat tctcaaagtg gcctataact acgaggagca
     4381 aggaaaaggt gttgtcatta tgacttcggc tctggatacg cgtgacggtg ttggctatgt
     4441 gtcgagtcga attggcatga aacgccctgc ccttacgatt gaggaaacaa cggatatctt
     4501 tggctatatc cgagacctac cagaaaaacc ttactgtgtt ttggtcgatg aagcccagtt
     4561 tctcaaacgc caccatgttt acgacctagc tcgtgttgtg gacgagttag acatacccgt
     4621 catggctttt ggcttgaaaa atgactttcg caatgaattg ttcgaaggtt ccaaatatct
     4681 cttgctttta gcagacaaga ttgacgaaat caagaccatc tgtcagtatt gcaagaaaaa
     4741 ggcgaccatg gtgttgcgaa cacaggatgg actgcccgtt tacgatggag aacagatcca
     4801 gattggtggt aatgaaacct atatttcggt ttgccgtaaa cattattttg cgccaatgat
     4861 aacctctaac aaggagcaaa actatgacaa ttgaactaag agatgttaca atggaaaatt
     4921 attttgatgt tttaaatttg gatgtcaagg aatatcaaaa acaattcatt gcaaccaacg
     4981 caattagttt agctgaagca tacgtctaca ctaaaaatgg agattttgta gctccattgg
     5041 cagtttatga taatgatgta attataggtt ttgtgatgat agcttatgat aaaaagatcg
     5101 taattagtag tggaaattat ttactatttc gttttatgat tgataagaat tttcaaaatc
     5161 aaggatattt taaaccaatt atggataaag tactagacta tgttcgaaca gcgccagcag
     5221 gtttaagcaa taaactttgg ttgtcttatg aaccagaaaa tgaacaggca agattttgtt
     5281 atctcagtta tggatttaaa gaaactgggg aaatatccga gaatgaagta gtagcaatct
     5341 atgatttaac aattgagaaa taaggagaaa aaatgaacat ctatgatcaa ctacaagctg
     5401 tagaagaccg ttatgaagaa ctaggagaat tgctgagtga ccctgatgtc gtttcagaca
     5461 ccaagcgttt tatggagctt tcaaaagaag aagcttccaa tcgtgacacc gtaatagcct
     5521 accgtgagta taaacaagtc cttcaaaata tcgtcgatgc cgaagagatg attaaggaat
     5581 caggcggaga tgcggacttg gaagaaatgg ccaagcaaga actcaaagat gccaaggctg
     5641 aaaaagaaga atatgaagaa aaactgaaaa ttttgctcct tccaaaggat ccaaacgatg
     5701 acaagaatat catccttgaa atccgtggag cagctggtgg agacgaagcg gcacttttcg
     5761 ctggagattt gctaactatg taccaaaagt atgcggaagc ccaaggttgg cgctttgaag
     5821 tcatggaagc ctctatgaat ggtgtcggtg gttttaaaga agtggttgct atggtttcag
     5881 gtcagtctgt atactctaag cttaagtatg aatcaggtgc ccaccgtgtg caacgtgttc
     5941 ctgtgacaga aagccaaggc cgtgttcata cttcgacagc gacagttctt gttatgccag
     6001 aagttgaaga ggttgaatac gacattgatc caaaagacct tcgtgtcgac atctatcacg
     6061 cctctggtgc tggtggacag aacgtcaata aggttgcgac tgccgttcgt atcgttcact
     6121 tgccaaccaa tatcaaggtt gagatgcagg aagaacgtac ccagcagaag aaccgcgaga
     6181 aggctatgaa gattatccgt gcacgcgtcg ctgaccactt tgctcagatt gctcaggatg
     6241 aacaagacgc tgagcgtaag tcgacaatcg gtactggtga ccgttcagaa cggatccgaa
     6301 cttataactt cccacaaaac cgtgtcacag accaccgtat cggcttgacc ctccaaaaac
     6361 tagatacgat tttgtctggt aaattggacg aagttgtgga tgccttggtg ctttatgacc
     6421 aaacacaaaa actagaagaa ttaaacaaat aatgaaatta gctcaattat tttcaaattt
     6481 tgaagaagag ttgataagac aaggagagga agcggaaagc ctctcttttg tctatcgtag
     6541 tctgaaaaat ctatctttta cagactttat ttttgccctc cagcaggagg tgacaacaga
     6601 ggaagaaaaa caatttgtag aagatattta ccagcaacta gcagctcaca agccagctca
     6661 gtacatcatt ggacaggcag atttttatgg aatgcattta aaggtggatg aacgggtttt
     6721 gattcctcgt ccagaaacag aggagttagt ggagcttatt ctaactgaaa atcttgagac
     6781 gaatctttca gttctggata ttggaacagg tagtggagct attgctctcg ctctagcaaa
     6841 aaatagacca gattggtcag tgacagcagc agatgtttct caagaggctt tagatttagc
     6901 tagcgaaaat gctaaaaatc aaaatcttca aatatttttt aaaaaatctg actgttttac
     6961 agaaatttct gaaaaatatg atataattgt ttccaatcca ccctatatct ctcgtgaaga
     7021 tgagtcagag gtaggcttga atgtcttgta ttcggagcct catctagctc tctttgcaga
     7081 cgaggatggc ctagctattt accgtagaat tgcggaagat gcaaaagact atctcaaaga
     7141 tggtggtaag atttaccttg aaattggata caagcaaggt caaagtgttc ccgaactttt
     7201 tagaaaacat cttcctgaaa aaaaagttcg aacactcaag gaccaatttg gtcaagatag
     7261 gatggtcgtg gttgatgatg gacaggatta gacaagagtt ggaaaatggt ggagctgtca
     7321 ttctgcctac agagacggtt tatggtcttt ttgccaaggc cttagacgaa aaagcagttg
     7381 accatgttta ccagctcaaa cgtcgtccta gagacaaggc gctcaatctc aatgttgcct
     7441 ctttagagga tatcttgcac ttttctaaga atcagccagc ttatctacaa aaacttgtag
     7501 agaccttttt gccaggtccc ttgaccatta ttctcgaagc caatgaccga gttccctatt
     7561 gggtaaattc tgaccttgca actattggat ttcggatgcc cagtcaccct atcacactgg
     7621 atttaattcg agagacaggt cccttgattg ggccgtctgc caatatctca ggtcaggcaa
     7681 gtggtgtaac ctttgaacaa attctgaagg attttgacca agaggttctg ggtctggaag
     7741 acgatgcttt tctaactgga caggattcaa ctattgtgga tttgtctgga gacaaggtga
     7801 aaatcttacg ccaaggcgca attaaacgag aagatattct tgctcggttg ccagagattt
     7861 cttttgagga ggcttgaaat gctaagagat ttgcaagaaa cagatgtgaa agcgatatgt
     7921 gacatcaacc aagaggcttt gggttatact tttagtccag aggaaacggc tagccaacta
     7981 gctagactgt ctcaggattc ccatcatttc ctacttggct atgaggatgc agctaatcat
     8041 gtcttacttg gatatgtcca cgctgaagtt tacgaatcac tctattccaa agcaggattt
     8101 aatatcttag ctttagcagt ttcacctcaa gcgcaaggtc aaggtatcgg taaaagttta
     8161 ctacaagggt tggaacaaga agccaaaaga tgtggttatg ggtttatccg cttaaattct
     8221 gccaatcatc gtctgggtgc tcatgcattt tatgaaaaag ttggctatac ttgtgataaa
     8281 atgcagaaac ggtttattcg catcttttag tttgattttc ttattgtaaa atcaaactaa
     8341 tggactagtc acacaataaa ggagaagacc tatgattttt gacaaagatg attttaaagc
     8401 atatgatgct gatctctgga atgctattgc caaagaagaa gaacgccaac aaaataatat
     8461 cgagttaatt gcttcggaaa acgtagtttc caaggctgtt atggcagctc aagggtctat
     8521 cttgacaaat aaatatgccg agggttaccc aggacgccgt tattatggtg gaactgatgt
     8581 agtagacgtt gtagagactc ttgctattga acgcgcaaaa gaaattttcg gtgctaaatt
     8641 tgccaatgtc caaccacatt caggaagcca agctaactgt gcggcttaca tgtccttgat
     8701 tgagccaggt gatacggtta tgggaatgga tttggcatca ggtggtcatt tgactcatgg
     8761 ggctcctgtt agcttctctg gtcaaaccta caactttgtt tcttatagtg ttgatcctga
     8821 aacggaactc ttagactttg atgctatctt gaaacaagcc caagaagtaa aaccaaaact
     8881 gattgtagct ggtgcttcag catattctca aattatcgat ttttcaaaat tccgtgaaat
     8941 cgcagatgct gtcggtgcga agctcatggt ggacatggcc catatcgctg gtttggttgc
     9001 ggctggcctt catccaagcc cagttccata cgctcatatc acaacaacaa cgacccacaa
     9061 aacccttcgt ggacctcgtg gtggtttgat tttgaccaat gacgaagaac ttgctaaaaa
     9121 aatcaattca gctattttcc caggtattca gggcggtcct ttagagcatg ttgtggcggc
     9181 taaagcagtt tctttcaaag aagttttgga tccagccttc aaggaatatg ctgccaatgt
     9241 aattaagaac agcaaggcta tggcagatgt cttcttgcaa gaccctgatt tccgtattat
     9301 ttcaggtgga actgaaaacc atctcttcct tgttgatgtg actaaggttg tagaaaacgg
     9361 aaaagttgct caaaacttgc tggatgaagt caatattacc ctaaataaaa attcaatccc
     9421 ttacgaaacc ttgtcgccat tcaagacaag tgggattcgt atcggagcag cagctattac
     9481 tgcacgtgga tttggtgaag aagaaagtcg caaagtggct gaactcatca ttaaaaccct
     9541 taagaattca gaaaatgagg ctgtattaga agaagtgaga agtgcagtca aagaattgac
     9601 agatgccttc ccattatacg aggactaaaa cttttatgga tatttatatt aagaaagcca
     9661 ttattcacca gttcagtccg gatgataccg agctgttctt agcagataag tttctcaata
     9721 ttactccaaa aatcgaagaa tacctacgta aaaaaattga acatgtgtat tcagatgaag
     9781 ccaagactgg gattttcgaa gaagaaaatc ccttcttcaa tcatattaca gacgatttgt
     9841 tggagacatc agtaacgctg gctaatctct ggaaagagga gtttagcatt tctgaaaatc
     9901 tcaagaccaa tgacttgatt tttgttcaat tttctaaaga aggtgtagaa catttcgctt
     9961 tcttgcgaat tgccctgcgg gagaccttga cccacctcgg aggagaagtt gataatccaa
    10021 tcaagctgac tcagaataac ctgcctggat ttggaacggg tgctgacgag gccttggtgg
    10081 tcaatcttca gagtcgcaag tatcacctga ttgaaaaacg aatcaagtac aacgggactt
    10141 ttttgaacta tttttcagat aatcttcttg ctgtcgctcc taagatttct cctaaaaaat
    10201 ctatcaagga actggaaaaa acagcccaga gaattgctga atcttttaac acagatgatt
    10261 ttcaatttca atccaaggtc aaatcagcga ttttcaacaa cctagaagaa agcaatgaat
    10321 tgtcacctga gaaattggct aatgaccttt ttgacaacaa tctgacggct cgtttgagct
    10381 ttattgacca agtcaaagaa gccgtaccag aacctgttca atttgatgaa attgatgcca
    10441 gtcgccaatt aaagaaattt gaaaaccaaa aactctcctt atcaaatgga attgagctca
    10501 tcgttcccaa taacgtctat caagacgccg agtctgttga gtttatccaa aacgaaaatg
    10561 gaacctactc tatcttaatc aaaaatatcg aggatatcca aagtaaataa tgtttaaacg
    10621 aattcgaaga gtgcttgtac tagcagtctt cctttttgct ggctataaag cttaccgcgt
    10681 tcatcaagat gtcaaacaag tcatgaccta tcaacccatg gtgcgagaaa tattgagtga
    10741 aaaagacacc ccagcaaacg aagagcttgt gcttgctatg atttatactg aaacaaaagg
    10801 aaaagaaggc gatgttatgc agtctagtga gtctgcaagt ggttccacca acaccatcaa
    10861 tgataatgcc tctagcattc ggcaaggcat tcaaactctg acaggcaatc tctatctggc
    10921 gcagaagaag ggtgtagata tctggacagc tgttcaagcc tataattttg gacctgccta
    10981 tatcgatttt atcgcccaaa atggcaagga aaataccttg gctctagcca aacagtactc
    11041 tcgtgagact gttgccccct tgcttggtaa tacgactgga aagacttata gttatattca
    11101 tcccatttcc atttttcacg gtgctgaact ctatgtaaat ggaggaaact attattattc
    11161 tagacaggta cgacttaacc tttacatcat caaatgtttc actctctttt caacatctgg
    11221 ctagaccagg tgtttttgtt ataagttttc tttaagatag atatattact ctaaagaagt
    11281 aaaggaggaa attccctatg agaaagaaac tctttctgac tagcgctgcg atcttgtggg
    11341 cagtaacagc tatgaatagc gtctatgcag caacagatgt tcaaaaagtt atcgatgaaa
    11401 cctatgtcca acctgaatat gtcctaggtt cttccctatc tgaagaccaa aaaaatcaaa
    11461 ctcttaaaaa actgggctac aatgcctcaa cagataccaa agaacttaag accatgacac
    11521 ctgatgttta ttctaaaatc atgaatgtgg ccaatgactc tagcttacag ttgtattcat
    11581 cagccaagat tcaaaagcta ggtgacaaat cgccacttga ggtcaagatt gaaacacctg
    11641 aaaacatcac taaggtaact caggatatgt accgaaatgc agccgtaact ttgggtgtgg
    11701 aacacgccaa aatcactgta gcagcaccca ttccagttac aggtgagagt gctttggctg
    11761 ggatctacta ttcgctagaa gctaatggag ccaaggtgcc gcaagccaat aaagatttgg
    11821 ctcaagaaga gctaaaggct ttgtcagata tcaatgctga aaacaaggac aaatcaggct
    11881 atgatgctaa taaattaaac gttgccctag ctgatatcaa gtcaggactc gccaaagcta
    11941 aagaaagcaa gggaaatctg acagaagaag atatccgcaa gattgttgaa gataccttaa
    12001 aaaattacaa acttgatcag gtcataacag gaaaccagat caatatcatc atcaattttg
    12061 ccttgaatct ctcaaagagt gatatcctca gcaatgcaga tttcactaaa accctaaatg
    12121 accttaaaca aagcatcgta tcacaagctg gcgacagttt taaaaatatc aaccttaact
    12181 ttgatgcgga taaggcgcta gaggacggtg gtaacttctt aagctccctc tggcaagccc
    12241 ttgtcaactt cttcaagagt tttggttctt aagaaatttc atggtataat ggatggtaac
    12301 cgtaacgttg ccgtcttttt tgtcggccaa tagaaagaga aaagaatgtt aaagaaaaat
    12361 gatattgtag aagttgaaat tgttgatttg acccatgaag gggcaggagt tgccaaggta
    12421 gatggtttgg tcttttttgt agagaatgct ttaccgagtg aaaaaattct catgcgtgtc
    12481 ctcaaggtca ataaaaagat tggctttgga aaagttgaaa aataccttgt ccagtcacca
    12541 caccgtaatc aagatctaga tttggcttac ctgcgttcag gaatcgcgga tttaggacac
    12601 ctttcttatc cagaacagct caagtttaaa accaagcaag tcaaggacag tctctacaag
    12661 attgctggaa ttgcagatgt agaagttgct gaaacgcttg gtatggaaca tccagtcaag
    12721 tatcgcaata aggcgcaggt gcccgttcgt cgagtgaatg gtgtcttgga aacaggattt
    12781 ttccgtaaga attcgcacaa cctcatgccc cttgaagatt tctttatcca ggatcctgtc
    12841 attgaccaag tcgtagtagc tcttcgagac ctgctccgtc gttttgattt aaaaccttat
    12901 gacgaaaagg aacagtctgg attgattcgg aatcttgtgg tgcgtcgtgg tcactattca
    12961 ggacaaatca tggtcgtttt ggtgacaact cgtccaaaag tttttcgtgt tgaccaattg
    13021 attgaacaag ttatcaagca gttcccagag attgtgtctg tcatgcaaaa tatcaacgac
    13081 cagaatacca atgcgatttt tggtaaggag tggcgcactc tttatggtca agactatatt
    13141 acggaccaga tgttgggaaa tgacttccaa atcgctggcc cagcctttta ccaagtcaat
    13201 actgaaatgg cggagaaact ctatcaaaca gccattgact ttgcagagtt aaaaaaagat
    13261 gacgtggtta ttgatgctta ttctggtatt ggaaccattg gtttatcagt cgccaagcat
    13321 gtcaaagaag tctacggtgt tgaactgatt ccagaagcgg ttgagaatag taaaaaaaat
    13381 gctcagctga acaatatttc aaacgcccat tatgtctgtg acacagctga aaatgctatg
    13441 aagaattggc ttaaagatgg gattcaacca accgttatct tggttgatcc tccacgcaag
    13501 ggcttgacag aaagctttat caaagcaagc gcccaaacag gagccgatcg catcgcctat
    13561 atctcctgca atgtcgcaac catggcgcgt gatatcaaac tctaccaaga attgggatat
    13621 gaattgaaga aagtccagcc ggtggatcta tttcctcaaa cgcatcacgt cgagacggta
    13681 gcacttttgt ccaaactcga tgtcgataag cacataagtg ttgaaattga gctggatgag
    13741 atgaatttga caagtgcgga gagcaaagca acatatgctc aaatcaaaga atatgtttgg
    13801 aataaatttg aattaaaagt ttcgacatta tatattgcac agataaaaaa gaaatgtgga
    13861 atagaattac gagaacatta caacaagtct aaaaaggata aacaaattat tccacagtgt
    13921 acacctgaaa aagaagaagc catcatggat gctttgagac acttcaaaat gatttaatag
    13981 aaaagaatga cagtatatga ctttctgcat ttattacatt cctacttggt ataggaacag
    14041 ctattattcc tttcttgcaa ggtatcaatt agaaaatagg ctcaatataa agattgatag
    14101 gatcattttt atatttaaag gagcgttgaa atgattgata aaggcaacaa aaaattttag
    14161 gataaatttg ctaagttgta tgcccctttt atgaaaaaag ataaagaggt ttatgataaa
    14221 gtttgtgaat atcttagtcc tcatttgaat aaagatatgg aggtgcttga acttgcttgt
    14281 tggtttcgtg tcataatagt tatagaggca aatagttatg taaatataag gagttcaaga
    14341 cttctaccaa agtttaaaac tcaaaaaata aatagttggt gtgctgctta tagtatccat
    14401 tttaataatg gatattgtaa ttagcatacc aatgaattta aagattcttt aaagagtctt
    14461 attttgtgat gaaaatttaa tatgtaaatc tcagacgata gaaattaaaa actctatcgt
    14521 cttttttata ctcaaaatta ggaggtaaaa atggtaagga taagaggtcc cacttaaaac
    14581 aatttatggc aaaataagga cggaataaca caacaaattc tctaaaacaa atcactaaat
    14641 caatgtaaga ttgaatgaaa tcaatattta tgctataatt aaataaatct aatgaagaaa
    14701 aaaagaggga tattatggca cttaactata aaccattatg gatacagtta gcaaaaaaag
    14761 gactaaagaa aacagatgta atagctatgg caggacttac aacaaatgtt atggcacaaa
    14821 tgggaaagga taaaccaatt acatttaaga atttagaaag aatatgtaag gctttatctt
    14881 gcactcctaa tgatattatt agttttgaag ataattttag tgatgaggaa tagaaaatga
    14941 ctttgaggac agaagatcaa gttagggatt atgcaagaga agtattaggc tttaatgaag
    15001 ttgaagaaaa catcaatcaa ggtactggtc aaataactac ttttaatcaa ttaggcttca
    15061 agggatattc agataagcca gatggttggt atttacctaa aaatatgaat gatgtagcaa
    15121 taatccttga aacaaaatca gaagaaagag atattagcaa acaaattttt attgatgagt
    15181 taatgaaaaa tatagacata atttaactaa aaataaaaac tagatccttt tttgaaaaaa
    15241 ttatattatt aaatttgtaa ctgtatctat tgacaatgat aattattatc gatacaatag
    15301 acttgaaata tgtttaagga gtttttatga aaaacaaatt ttttctaata gctattttag
    15361 ctatgtgtat agtttttagc gcttgttctt ctaattctgt taaaaatgaa gaaaatactt
    15421 ctaaagagca tgcgcctgat aaaatagttt tagatcatgc tttcggtcaa actatattag
    15481 ataaaaaacc tgaaagagtt gcaactattg cttggggaaa tcatgatgta gcattagctt
    15541 taggaatagt tcctgttgga ttttcaaaag caaattacgg tgtaagtgct gataaaggag
    15601 ttttaccatg gacagaagaa aaaatcaaag aactaaatgg taaagctaac ctatttgacg
    15661 atttggatgg acttaacttt gaagcaatat caaattctaa accagatgtt atcttagcag
    15721 gttattctgg tataactaaa gaagattatg acactctatc aaaaattgct cctgtagcag
    15781 catacaaatc taaaccttgg caaactttat ggagagatat gattaaaatt gattcaaaag
    15841 ccttaggtat ggaaaaagaa ggtgatgagt taatcaaaaa tactgaagct cgtatatcca
    15901 aagaattaga aaaacatcca gaaatcaaag gaaaaatcaa aggaaaaaaa gtattattta
    15961 ctatgattaa tgctgcagat acatcaaaat tctggattta tactagcaaa gatccaagag
    16021 caaattattt aacagattta ggtctagttt tccctgaatc attaaaagaa tttgagagtg
    16081 aagatagttt tgcaaaggaa atttctgcag aagaagcaaa taagataaat gatgctgatg
    16141 taatcataac ttatggtgat gataaaactc ttgaagcttt acaaaaagat cctcttttag
    16201 gtaaaataaa tgcaattaaa aatggtgccg ttgctgtaat tccagataat acaccgttag
    16261 cagcctcatg cactccaaca ccactttcaa taaactatac tattgaagaa tacctaaatc
    16321 ttttaggaaa tgcatgcaaa aatgcgaaat aaaaaacaaa taaacctagg cataattttt
    16381 gtaatctgcc taggtcttct tattacaata tttttgtcat taaagcttgg aacaaaagaa
    16441 attaatatca gagatttttt agcagctttt ggaatgggta atacaaatga tgattttatt
    16501 aaatcaatta tatataaaag aatacctaga actatttttg caattttagc aggttctagt
    16561 cttgccataa gcggtgtatt gatgcaatca gttactagaa acccaatagc tgatccaggt
    16621 atactcggta taaacacagg agcaagtctt agtgtagtaa ttggtctttc ttttttagga
    16681 atttcatcaa gcataagcca tataagtttt gcaatcattg gtggcttagt aagtgcaatt
    16741 tttgtatacg cgattgctgt aagcggaaaa gcaggcctta cccctataaa acttgcctta
    16801 tcaggaactt gtgttagtat ggctttaagc agttttgtaa gttttttaat tttaccgaat
    16861 aataacgtct tagacaaatt tagattttgg caaataggta gccttggagc agctacatta
    16921 tcttctatat ctacactact accttttata attttaggtc acttgatagc tatatttatt
    16981 tcatcagatt taaacgcttt agctatgggt gatgaaatgg ctgttggtct tggagttaat
    17041 gttaatagga taagatcact tgcaataatt gcaagtgtgc ttttatgttc aagtattact
    17101 gcaattggtg gacctattgg cttcgtaggt cttatagttc ctcacttttg tggcttattt
    17161 ataagcaaag atatacgcac aatgaccatt tcttcatctt ttataggtgc agagctcttg
    17221 cttatatgtg atataatcgg ccgtatgtta ggtaaaccag gtgaaattga agtagggata
    17281 attactgcaa taatcggggg tccagtactt atttatgtaa ctatgaaaaa tagaggggtt
    17341 aataactaat gcaaaattta attataggta ttcaaaaaag aaaaaataga ataacactat
    17401 tttcctcact atttttatta ataataatca gtctatcatt tttcatttta cttatcggag
    17461 atgaaagtta ttctttttca actttgatta aagtcttaaa tagtgaaact gttcctggag
    17521 ctagtttttc gattatggaa attagattac caaaattatt agcaggaatt atagctggct
    17581 ggtcttttgg attggcagga tttatctttc aaactatgtt aagaaatcct cttgcaagtc
    17641 ctgatataat cggtgtcaca agttcttcat ctattgcagc ggtcttttgc atattggtat
    17701 taaaaacaaa tagtttaact actggaatta tttcaataac ttgtggacta acatcatctt
    17761 taatattatt tttactagct aaaaaagatg gtttttcagc agcaagactg ataatattag
    17821 gtattggttt tcaagctgtc acaagagcag gcacctcatt tttattgttg aaagtagcaa
    17881 gatatgaatt acaagaagtt atgagatggc tcagtggctc tttatctttt gcaaagttag
    17941 atgacatacc tcttgttcta atagtaagta ttattgctac tatattagtt ttatttttta
    18001 ataaaagact agaaattatt gaacttggtg aagaaatagc aatcggactt ggagcaaatc
    18061 ccgagctttc aaggcttgtt ttaatttttt gcgctgtatc tttaactgct ttttctactt
    18121 caattacagg accaatagct tgtatatctt ttttagctgg tcccatagcc ttaaatattg
    18181 gcaagaaaag aagcccaata ttagctggat tggttggaat tttactagtt ttgttatcag
    18241 acatattctc tcaaaatatt ttaccagcta gatatccagt aggtgttgta actggcttgt
    18301 taggttcacc atacttaata tacttactaa taaaaatgaa caggaggaat atataatgaa
    18361 aggtctgtgg tcaaataatc ttacctgcgg ttatgatgaa aaaataatct tggaaaatat
    18421 aaatataaaa atacctgaag aaaaaatatc agttattatt gggtcaaatg gttgtgggaa
    18481 atcaacactc attaaaacct tgtctcgact tataaagcca ttagagggag aagtattgct
    18541 tgataataaa tcaattaatt cttataaaga aaaagattta gcaaaacaca tagctatatt
    18601 acctcaatct ccaataatcc ctgaatcaat aacagtagct gatcttgtaa gccgtggtcg
    18661 tttcccctac agaaagcctt ttaagagtct tggaaaagat gaccttgaaa taataaacag
    18721 atcaatggtt aaggccaatg ttgaagatct agcaaataac ctagttgaag aactttctgg
    18781 gggtcaaagg caaagagtat ggatagctct agccctagcc caagatacaa gtatcctact
    18841 tttagatgag ccaactactt acttggatat ctcatatcaa atagaactat tagacctctt
    18901 gactgatcta aaccaaaaat ataagacaac catttgcatg attttgcacg atataaatct
    18961 aacagcaaga tacgctgatt acctatttgc aattaaagaa ggtaaacttg ttgcagaggg
    19021 aaagcctgaa gatatactaa atgataaact agttaaagat atctttaatc ttgaagcaaa
    19081 aattatacgt gaccctattt ccaattcgcc tctaatgatt cctattggca agcaccatgt
    19141 tagctcttaa taattgaata tcggaattca tttaaaagtc gcaaattttg aactgaccct
    19201 caaaagttag gccaaaaaac taactaaagg aggtcagttt tttaatggca aatacagcac
    19261 agaatttaag ataaaattag taaaagaata tcatgaatga aaaataggat atagataata
    19321 acagcaatat taaaaagatc aggactgata ataaacaaaa agaaagtaca acgactagtt
    19381 caaaagctaa aacttcaagt aaaaagttat tcaagaaaat ctagaaaata ctcatcctac
    19441 aaaggacagg taggaaaaat atcagacaac aaaataaaaa gaaatattta ttaccgaaaa
    19501 aaaggggaaa tcgagtcaag taccaacagg ctcatctatt ccaaaaagat atttactcga
    19561 tggaaaaact cctagaatta gtgctacaaa tattgacaat ggtatcttag gttactacga
    19621 agatatagat gataaaaatt atagagtttt tgaaaatttt atatctgttt catttttagg
    19681 agcagtcttt tatcataaat ataaagcaag cctagatatg aaaattcatt gtttaaaatt
    19741 aaaaaataaa gaattgaata aagaagtagc attctattta acttcaatta ttaggcaagc
    19801 tttaaaaaat actgaatata aagatcaaat atctagcaca gtattgccag atatcaaaat
    19861 taaattaccg atagacagta gaggtactcc agattggaat tacatggaaa gatatataga
    19921 agacttaaaa ttaaaatgca atatagcaaa ttataatatt taaaacaaga acgattagaa
    19981 ataaaaatct agtcgttttt tatttttaga aaggatacat gatggcaagt aaaagattaa
    20041 gtattgaaga acagattgaa aagaaagaag aaagcattaa gcaattacaa aatcaaaaaa
    20101 gacagttgaa gaaaaaactt aatgaacaag aaagaaaagc aagaaacaaa agacttatag
    20161 aaaaaggtgc agtgtttgaa agtatttttg aagaaagtat tgatttaaca aaagatgaat
    20221 tttataagtt aataaaaacg ttaaatgatg aagaaataag attaaacata atggaaattt
    20281 tagaagaaag aatagatgat aatgtagaaa aatcatctaa agatgaaata acataattgt
    20341 cccttggtta caagggcgca attatacacc ctaaagggtg cttgcgtcct gcggagtcaa
    20401 acccttgcag ggagtaacaa ccattcgctt tttaaaagtc aagggtaaat aaactcgcta
    20461 aggctcgccc ttgactttta aaatttgaaa tgaaagtaac aattaagccg acatactgaa
    20521 acaacaaaaa ttaattcagt agtcggcttt tttaattcta tcatttcaaa acgctcattc
    20581 acaaagagga tataaaaaaa ctattaagcc tccacctaaa acaacaaaga aaggaagtga
    20641 taaaaatggc agacagtttt catttttcag taaacataat atcaagagga aaaggcaaaa
    20701 gtgcagtagc aagtgcagca tatataagtg gagaaaaaat aaaaaatgaa tgggacggag
    20761 taacccatga ctatacaaga aaagaaaaaa tattagtaaa aaatataata ttgcctgatc
    20821 atataccaaa agaatttaat gataggtcta ccttatggaa taaagtagaa atggcagaaa
    20881 aaaattctaa tgcacaacta gcaagacaat tcataatagg actaccaaaa gagttatctt
    20941 taagtgaaaa taaaaacctg gttgaaagat atataaaaga aaatttaaca tcacaaggaa
    21001 tgatagtaga ttatgcaatt catgatgaga gtcaagataa aaatggaaat atccattgtc
    21061 atataatgac cataatgcga ccaataaacg aaaaaggaga gttcttagcc aagtcaaaaa
    21121 aagaatatat cctagatgaa aaaggagaaa aagtattaaa caaaaatgga aaaccaaaga
    21181 caagaaaagt agaactaaca acctggaacg atacaggcaa tgtagaaaaa tggagagaaa
    21241 atttttcaga tctttgtaac aaatatttag aaagagcagg agcagaaaaa agagtagacc
    21301 ataggagttt taaaagacaa aattcagatt atctaccgac aatccattta ggatcagcag
    21361 caagtgcaat ggaaagaaag ggaatagaaa ctgacaaggg aaactataat agagaaataa
    21421 gaaaatataa tcaacttgta aaaacaataa aagaagagat aaaaacatta aagggttgga
    21481 taggaaattt attagataac ttatctactg cttatgaaaa atttaaggat atagaaagag
    21541 ataaggtaat agacaaccct aaacttttta atctaacaaa ttatctatta acttattcag
    21601 aaattcaaaa agaaaaaagt aaatatctaa aaggatatgc aaaaactaat aaagaaaaat
    21661 atgacttcaa aaagctaaca agtgcatata gttatttaag aaaaaacaac atagaaacca
    21721 taggtcagtt acaaacaaaa atagaaactt taaagtctaa tagttatagg ctaaataaaa
    21781 aagcaaagac aatccataaa gaaatggaag atgtagaaaa gaaaattcta tactatgaaa
    21841 tctacaaagc caaaaaagaa gtttatgaag aatatcaaaa gaaaaatata ttcacaaaag
    21901 aagcatttta taacaaacat aagaaagata tagaccaata taaagtagta agtgggaaat
    21961 taaaaaaact cctatcagat aaggaaaaac taagtcctaa aaagtggaat gaagaaaaaa
    22021 ttcttttaat gtcaaatctt gaagaaataa ataaagaaaa agacaagata aaagatgaat
    22081 accaggaaat taatcatata aaatattcag tagattttgt aaacaaagaa cttggtatag
    22141 atttatccat agaaatagat aagctaataa aacagggaga aaaaccaagt gtaatagcac
    22201 agattaaaaa gttccaagac caagtcaata aagataatga atacagagaa atgatgaaaa
    22261 acaagaaaat ggatcaagaa agataagacc tggtaaaaat atcttatcca agctataata
    22321 tgaccaaaca actaaagtca gatctaggag gtaatagaga tgaataaaag gcaagagcta
    22381 atagatgaac tcataaaagc aaatgaagat ggaacataca aaacctataa aagcacagaa
    22441 gaaataaaag caatgaacaa tgaagaaata cagattatat attctaacat gaaaaactat
    22501 ctatcagaca aaagaacaca cataaactat taaaggtgga aaggtagtgt aagctatttt
    22561 taaaagtata aaaggtacaa agacctaaga aatatataaa aacatcaaaa taaagtattc
    22621 caccaccaag aacaataaaa taaaaacaag caaagggaag tatagaaaaa ttaaaaccta
    22681 tacttccctt ttttaattca aacaaaggag agaaaagcat gataaacgaa gaaataagca
    22741 aggaagcagg tcaagcagca caaaccataa tatcatacac aataaaggca acaaaagaat
    22801 caatcaattt agaaaaagaa ataagaaaaa agatgaatga aactttagaa aaagcaaatg
    22861 gaaacttaaa aagtcttatg ggcgatgaaa tgaaaataaa agacctctac aagaaaggac
    22921 aactagaaaa tataagcata gatcaaatcg acctcaaaga cttaaaaaaa gaactaaaca
    22981 aacttggagt aagtttctca gtaatgaaaa acaaagaaag caaaaactat gaaatattct
    23041 tccaagccaa agacataaaa gtaatggaat atgcctttaa gcaagtcata gccaaggaaa
    23101 ataaaaaaga aaaagaaagt atcctaaaac aaataaagaa atacaaagac ctatccaaaa
    23161 acaaagataa gacaaaagaa aaaggaaaaa ggaaagtaaa agaaaaagta aaaccaaaca
    23221 aaaaagatat gaccagagaa atctaaaggg agtaacgaaa agttacaccc ttaaataacc
    23281 ataataacaa gacttccgaa aaacagaagt ccagaattcc gaaaatcgga aatcaagaat
    23341 ttcgattatc gaaaatcaag aaaggagcag atatggcaac aaacaaaaga tactattgga
    23401 taaaattaaa agaagaattt ttcacagaca aaaggataaa aaggttaagg agaatatctg
    23461 gaggagatac ctatacgata atctacctaa aacttctact actaagccta aaagatgagg
    23521 gcaaactcta ttatgacgga gtagaaagtg attttataaa agagttagca ctaaccatag
    23581 atgaaacaga cgatgatgta atggtaacag taaattattt aatcaatcaa ggcttattag
    23641 aagttgtaac agaaaatgat gaatactacc taactgaaat accaaactta atcggatcag
    23701 aaacagcctg ggcagagaaa aaaagaagat acagacaaaa taaacagagg acattgtcct
    23761 taatgagtcc aacccatgtc cgacaagaga tagagataga gaaagatata gagatagata
    23821 aagagagaga gggagagata gataaaaagt ccacccccat tttttatgga gaattcaaaa
    23881 atgtaaggtt aagcaaagaa gaatataaaa atctaaaaga aaaattaaac tcacacacag
    23941 atataatgat aaataaacta tccagataca tggaaagcag tggtaagacc tatcaaaacc
    24001 actatgtgac aatcttaaaa tggtatgaag aagataaaga caaactaaga cagaaaggtt
    24061 taaataaaaa aatgaattat gatgtaggag aatctttata gataaaaaga ggtggaaagg
    24121 cactattaaa gactttaagt ttaaaaaggt atcaaagtat gccagagata aaaaaatata
    24181 aatatgacac tttaaaggcg attagaaaat taaagaaatg ctagaagact tttagatgac
    24241 agttaccaag agggtctaat tttcactgct acttatgcag taggaattgg acctttttat
    24301 ataagcaaat tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat
    24361 aagagggtaa tttatagaat tttgttacat caagataaat attttctgat ggtcaaattt
    24421 taaaaagatt aataactctc gataaatttt gaaccttaac aattgaatag accaagacaa
    24481 gacgttaatt atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt
    24541 cggcaaaaaa agttctgcta agcaaaaaga aagtgagcga taagtaagag tttgaatata
    24601 gggagggata ccctatccgc tatgaagaaa atgaggataa tgatacttct aaggttgaag
    24661 caggctcatc cggaatagag gcggaggtga gattcctatg ttgctaatcc aaagcacttg
    24721 tcaatgtcaa aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta
    24781 tatattggac aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata
    24841 tgctggtgct ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat
    24901 gaaaaatagt tttgacatgg caaaaacaca aattgagacg gactaataaa agtgttataa
    24961 tatacttgaa atgatagtcc aaacttaaat taaaaaaatt atatatgata tagaaaaatt
    25021 atattgaggt taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat
    25081 ctacgtcaat acagatagag gggtattcgt tagaggcaca aaaatcacga atgaaagctt
    25141 ttgctattta caatgattat gaaattgttg gagaatatga agatgccggg aagtctggca
    25201 agtctattga aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag
    25261 atggagtatc ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg
    25321 ttctttctac acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg
    25381 gcattgattc atctaaagat gctgggaaac taatgatttc tgttttatca gctgtggctg
    25441 aaatagaaag agaaaacatc cgtattcaaa caatggaagg tcgcattcaa aaagcaaggg
    25501 aaggaaaatg gaatggtggc tttgctccgt atggatataa acttgaagac ggcaagctgt
    25561 ttataaatga ggaagaggca gttgcaataa gaacgatttt cgaccagtat gtaaatacta
    25621 cgataggagc caatgggata tctaaatact tagagaatca tggaattaga aaaatcccaa
    25681 gacagaatgg taagaatcct ttgtttgatg caggtcttat aagaaagata ttaaagaatc
    25741 ctgtatataa tgggaaaata gcatttggaa gaagaacttt agaaaaagtt catggtacaa
    25801 gaaatgaata taagcaggtt gaacaagatg aatatctaat atctgaaggg atacatgaag
    25861 ctatagtttc cgatgaagtt tggcaagctg ctcaggttaa gctaaaatct caagcaaaga
    25921 aatatgagca tgtgaataaa ggaaaagata cacgcacaca cttgctttct ggaattgtaa
    25981 aatgcccgat atgtggagtg ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg
    26041 gcacaaagta taaagatttt tattactatg gttataaaca taggcagatg ataagaggtc
    26101 ataagtgtac attcagtaag caaattagag aagaattgtt agatgatgct gttgcagagg
    26161 tgattgtcaa gatagtaagt aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca
    26221 tgaaggtgga tacctctgaa atagaaaaag aaatagataa ttaccaaaag gaattgagaa
    26281 agagtcattc tacaaagttt aagctaattg aggaaataga taatttagat gttgaagata
    26341 agcattataa gagaaggaaa caggatttag atgatagact atatcgtatg tatgacaaaa
    26401 tagatgaatt agaatcatca ctaattgatg cgaaagcaaa gaaacagact attgaagctg
    26461 aaaagcttac aggagataac atatataagg ttctgatcta ttttgataag ctctataaag
    26521 tcatgaatga tgtagagcgt aggcagttaa tttcagcttt gatttctgaa attcaagttt
    26581 atgaagaaaa acaatctaac ggacaatggc taaaatccat tacttttaag ctaccaatta
    26641 tagaagaaaa tctcaacata ggtttggata atgatgaaca agttgaatgt gtaagtttat
    26701 tagagaaacg tagttaatcc tcaaaaggtt ccccaaacct tttgagtccc actgacgcat
    26761 cacgctgagg cggtatcact gcttgtacga gttgaagcat cagcgaagta aaagtagatg
    26821 ttcagccaat gcgacgaggt gagaccgaag gtcgataagg tgtgttctgg gtataggact
    26881 cgtaaagtaa gtaggaaata tgatgagatg atacagagag catgaattgg tcaggtgacg
    26941 tgcttattta cattagcctg ataatgaaaa tggagagatt atcgatggtt atattggaat
    27001 tgtaccaaaa tgattattct aaagatttag tagcatttga ttccatagaa gatgggaaag
    27061 cctttgtagc tcaaatcccg ggatacactc tggaaacaga agatggtttt gaagtggagt
    27121 attttaatcc taaaaacata ccggattata tggaaattat ttttaacgga aatattgttc
    27181 ctttatctaa atttatgttc gatcctgagg aaaatgtaaa cattatttgg aaagagattt
    27241 caaatttatc cctcaaaaat gatagagtga tcgaaggata ttcaaaaatt gatgcatatg
    27301 tcgttaacaa ccatgaagtt aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag
    27361 caaaagactt cttagaaagc cgcggatatg aaatcgacag aagctttttc ggaagtgaag
    27421 acggtgaagc gattctttac agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact
    27481 tagacccaat gtttgtagag attgaagatg tagaaggata tgttaaagaa gaagttggag
    27541 agattcaata gtcaaccaaa gttccttgtg agtatatacc tttgctagta aaagagtcaa
    27601 aacgttataa cgaagggggg aagaaaaccc ttgagtgtaa gtctttttct tgtttagagg
    27661 gaaagtatta gagtagccgc tcataattta tactagattt gataactgat ttgagacaga
    27721 ttttatttct ataaatattg tgaaaatttt ttaataccaa agatttaaag ttactgtgtt
    27781 aaaaatcctc tccactttta aactaatgta ttataaaagc cagttgacac aagtgttaca
    27841 cctatgatag aattaacttg aggtgatgaa aatggcaacc gataaaaata gaataatgat
    27901 tagcttggat gataaaaatc tagagaaact tgaaaattta gtagaagatg ctagagatag
    27961 aaggggaatg cgactaacaa agtcccaggt tattgaatta ctcctaaata ccgttgatta
    28021 tttcgatgat attatggggg ctatttactc aaaaaaataa gagcaaaatt gctattattt
    28081 tttacaaatt ggtgtaacac tagtgatata ggagtgatga aatggttgtt tatattagac
    28141 aaagtaaatt accaagtgag gtttcaatta ataaatacaa tgctcaagta ggtgcctact
    28201 tacaaggaga agaagttatt ttatatcaat ctttttctga aataaaagag ttaacaagtg
    28261 aagatatagt tgtagattat ataatggaga ctagagcatt actaaaaatg atgggcttaa
    28321 acgttccggt tcatgactat cctattgagc ttaaagagtt ttatggtcga aagatttatg
    28381 ctggtatttt aggagagatt gtgaatatac ctgataattg gggaaaattt attaagccta
    28441 aagctggttc aaaagtcttt actggaagag ttgttaatgg aacccatgat ttaataggta
    28501 ttggtctacc tttcgactat cctatatgga ttagtgaggt tgtagaattc atagctgaat
    28561 ggcgttgttt tgtgttagat ggtcgcgtat tagatgttcg accctataca ggtgattatc
    28621 atgcacaatt tgatgcaagt gtaattgatg aagcgatatc atgttggaaa gatgcgccaa
    28681 tagcttatgg actagatatc ggtgttactc gcgatggcag aacacttgtt gttgaagtaa
    28741 atgatggtta tgcattggga aattatggcc tatctccttt aaaatcaatc aattttcata
    28801 gagctaggtg gaaagaaatg gtaaaaccct attttgaaaa aaatgaaatt tttaaaatcc
    28861 aacaggatgt tattttctaa aataaatatg gtagataacc aatataaaaa gcatcaaaat
    28921 gaacaaggag gaatctgatg cttggagcaa ttattggaga tattgtcggt tctgtttacg
    28981 aatggaacaa tatcaaaaca aaggactttc ctttatttcg gaaggactgc ttttttacag
    29041 atgacacggt tatgacctgt gctgttgcag aagcaattat gaatggtgga caaaaagacg
    29101 acttcattga cgcgatgaag aaatatggca gaatgtatcc gaatgctgat tacggtgctc
    29161 ggtttaatgc atggctaaac agcgataacc gtgagcctta taatagcttt gggaatggat
    29221 cagctatgcg tatttctcca tgtgcttgga tcatggactg tggtttttat gcgaaaactg
    29281 gtatatggcc atcatctaga ggacttacga gtctttctgc agaggtaact cataatcatc
    29341 cagaaggtgt caaaggcgct atggctacag ctgatgctat ctttctatgt cgtttttact
    29401 ttggtggtta ttgtagagag tacgagcaat caattaacga caatcctaca gagtgtaaaa
    29461 gacgaattaa ggattatata gaaaaagaat acgattacaa tctatctcaa actttagatg
    29521 aaatccgtcc taactatcgt tttaacgaaa catgtcagga aactgtccct caagccatta
    29581 tcgcctttct tgaaagtaga gacttcgaag atgcgataag aaatgccatc tcacttggtg
    29641 gcgacagtga tactctcgca gcaatcactt gtagcatagc agaggcagct tacggtattc
    29701 ctgattggat caaggataag gcctattctt acttggatga acccttaaag gatgtagtta
    29761 ggcgatggga aaatagaata aaagcgtatt aatctccagt acgtcagatt tctcttttct
    29821 gtattttcat tgtataatag gattacattt acttgcatac gacgaaatgt aaacatttct
    29881 gtttaaaatt aaggataaaa tcaatgaaaa aagcaatggt aattatcaac cctacttctg
    29941 gtggcgagaa ggctttggat tacaaagaaa agctggagaa taaagcaaaa gaatactttg
    30001 aatatgttga aaccaaaatt accgaaaaag cgctggatgc aacacatttt gctgaagaag
    30061 cttctcgtga gcagtatgat gcagtggttg tgtttggtgg agatggaact gtcaatgaag
    30121 tcatttcagg tattgatgag agagactaca ttcctaagtt agggattatc ccaggcggta
    30181 cgggtaacct cattacaaaa cttttggaaa tcaatcaaga catcgatggc gcaattgacg
    30241 aactggattt tgatttaacc aataagattg atatcggtaa agcaaatgac aactattttg
    30301 gttatatctt tagtatcggt tctctgcctg aggcgattca caatgttgaa atagaggaca
    30361 aaacaaaatt cggtatttta acctatgctg taaataccat gaagtctgtc atgacagatc
    30421 aggtctttaa cattaaggtt gagacagaaa atggaaatta tgttggtgaa gctagccatg
    30481 ttttggtcct tttgacaaat tacttcgctg ataagaaaat ctttgaagaa aacaaggacg
    30541 gctatgccaa cattttgatt ctgaaagatg cctctatatt ctccaaatta tccgtcattc
    30601 ctgatttatt aaaaggggat gttgtcgcaa atgataatat cgagtatatc aaagcgcgta
    30661 atattaaaat ctcttcagat agtgaattgg agtcagatgt tgacggagat aaatcagata
    30721 acctacctgt agaaatcaaa gtcctagctc agcgagtaga agtattttca aaaccgaaag
    30781 aggattagta tatagagaaa gcctttttta aggctttttg tatactttaa aagatagttc
    30841 ctttaacaac ggacattcct tgcaaatagt ttacaaaaat agtatactgg atttattgag
    30901 tttgaaaacg tttgcgtaaa atttgaatga atactttagg agacaaattg atggaattga
    30961 gtgctattta ccataggcct gagtcggagt atgcctatct ttataaggat aagaaactcc
    31021 atattcgaat tcgaactaag aaaggggaca ttgaaagcat caacttgcac tatggggacc
    31081 cttttatctt tatggaggag ttttatcagg atacaaaaga aatggtcaag ataacttctg
    31141 gtaccttatt tgaccattgg caggttgaag tgtcagttga ctttgcacgt atccagtatc
    31201 tctttgagct cagagataca gaaggtcaaa atattttgta tggcgataaa gggtgtgtgg
    31261 aaaattctct agaaaatctt catgcaattg ggaatggatt taagttgcct tatcttcatg
    31321 agattgatgc ctgcaaggtt gactgggttt caaatacggt atggtatcag atatttcctg
    31381 aaagatttgc caatggcaat gctctattaa acccagaagg gactttagac tgggattcat
    31441 ctgtcacacc taagagcgat gatttctttg gtggtgattt acaggggatt attgatcata
    31501 tggattactt gcaagacttg ggtattactg gactatatct ttgtcccatc tttgaatcta
    31561 caagcaatca caagtacaat acgacagatt actttgaaat tgaccgtcat tttggagaca
    31621 aggagacctt tcgggaactg gtggatcaag cgcatcatcg tggcatgaaa gtcatgctgg
    31681 atgcggtatt taatcatatt ggttcgcaat ctcttcaatg gaaaaatgtc gtcaaaaatg
    31741 gtgaacagtc tgcttataag gattggttcc atattcaaca attcccagtg acaactgaaa
    31801 agctagttaa taagagagac ttaccctatc atgtttttgg tttcgaggac tatatgccta
    31861 agctaaatac agccaatcca gaggtcaaga attatctttt aaaggttgcg acttattgga
    31921 ttgaagagtt taatatcgat gcttggcgtt tggatgtggc taatgagatt gaccatcagt
    31981 tctggaagga ttttcgtaag gcagttttag ctaaaaatcc tgatcttttc gagattataa
    32041 aaaatataaa gaatctagtc ataaatttga attgaaacaa cgtctttatt ttttgcttca
    32101 gcaatctaaa tcgtttgatg attttttaga gaaagcaaag cagttgcatg ttcagattga
    32161 ttttagtcaa aagcatagcc gttttttgat gacagataga acgatgataa aaccaattcg
    32221 agggcgccaa ctcagcaaac gagatctata tgatgaagaa ttttttagaa cgcattttgc
    32281 taagcaagag attgaaagtc gtttagaatt tttgttaaac cgtgtcaatt ctttagaaga
    32341 tttaataaca aaagcaaaag aattgaatct aaccattgac ttaaaacaaa aaatgtaact
    32401 tttatcctgg aagaaaataa tcaaaagata agtttgggtc atcaaaaaat aagtgataag
    32461 aaattatatg atgtcaaatt ttttcaagat tattttaaaa ataaggaagt cgttgcttca
    32521 gaaggattag agaatttaca ggaacagtac catgctttcc aagaagaacg agataaggat
    32581 aaagtatcca ctgaagagat tgagaaagcc tttaagacat ttaaggaaaa atgagatacc
    32641 gttcgtgaat ttgaagtgga acttgcagag aaccaaatag agaagctagt tgataagggc
    32701 gtctatatca aggtgtcttt cggtgtcaaa cagagcggtc ttattttcat tcccaactat
    32761 caattggata ttatggaaga agaaaatcat aaaaaatata aagtctacat tcgagaaacg
    32821 tcttcttact ttgtctataa taaagaaaac atggataata attgtttcat caagggtagg
    32881 accttaatca gacaattgag caacgatagc caaaaactcc cctatagacg accaacttta
    32941 aaaagtcttc aagagaagat ttctgaaatt aatcttatga ttgaactatc taacacgaac
    33001 aaacaatacc aagaaatcaa agatgagcat gtattagaaa ttgcagagat tgatatgaag
    33061 ctagaagaaa cccaagaaaa aatcgccacc ttaaacaaga tggcggaagt ccttatcaat
    33121 ttgaagagtg aagatcatga gactagaaaa ttagctaagt atgattttga ccaaatgaac
    33181 atgacggaat caataatgtt agatcgactc aatacagata ttttaaaatt acaacaggaa
    33241 cttggtaatg aaattaataa atatgaggag atagctagaa gattggattt gtttgtgaaa
    33301 attattaata ccaataaatt tacagttcta aaatttcacg agaatgcctt actagaataa
    33361 tattatttac gactaattag ttaaaagata gagaatcatt tcatttattg tttacaagtt
    33421 tatcaaaatg gctagtatag tgtaatttta acttgtcttc tcctaaaata tcgagaactt
    33481 gtatagcttg tttcattgtt tcaataccac tacttaattg acgtttaaat tcatagtaac
    33541 cggttgcata gagaaaaact gtctgttcat aaaagtttaa ttcattctct aacaatccct
    33601 ttatctcatt aattaaataa gagcaattag aaaattcttc tttatctatg ctgagaatga
    33661 aacaatttat agctagctga gtgacaatcc gcttatttgt tttatttaga gatgagtaaa
    33721 tataattatt taacatttct ttagttaata agaagtagga gttgtagtta attgttcgta
    33781 cacagttacc taataaaata atctcataat aaccccattt ttcaacttta aagagataat
    33841 ctgctagttg aagtaattca tcatctgatg gaatgattct tgaatccatt gtgtgtaaaa
    33901 tggattttac cattgttttt tcaaaagaat ctaaagtgta atttgaggaa tccgaaagta
    33961 gagattgtat attattgatg ttttgtaatg aatattgttt acggatatac tgtattaagt
    34021 tggcaaatga ctcagttttt gtatagtctt catcgtgtaa aataagaaac tcatccaaag
    34081 taatgtgtaa tttgtctaaa atattgatca gtcggataca tgatatctct gactctccac
    34141 gttcaaatcg ggatatttgc gattttgaaa gatgctcatc agcaacagag catagactga
    34201 tttgtttgcc tttacgaact tttctaagtg tgatgccaag ttttgatttc atagtttttc
    34261 ccattctccc aacaaaaagt taacttagtt ttatttattg tacaataaat aaaaattgaa
    34321 aggaagtcta aatatgaaga aaatttcaaa atttttccca attttgatgc tagtgatgga
    34381 cattatcatt attgttggtg gttaaatcac ttaggtgtac acctaagtct ttagagtatc
    34441 taaagactat acttactagc taaaacatat ttaagttaaa tcgtaaaatt ttagagagtg
    34501 gtgagacttt gaaacataaa aaagtattaa ttatagggta tggtataatg actcggggta
    34561 tattaaaaat cctgaaacag tcgaaaaaat ataatatata cctatatagt aggcatctaa
    34621 attcaacaat aaatggaata atatttatta gagaagatga attacctgat gctataaatc
    34681 aggttgattt tataatcact tgttttagta atcatattga aacggataat ttcattaatg
    34741 agtttttatt aaatatacaa tcacttcgta aaaccatagt aattgatttt acaacctcca
    34801 ggattgattg cgttgaaaaa tttaaaaaaa ctgttgaaat taaaggggga tactatatag
    34861 aggctccttt cacaggaggt aagttaggaa gtaatagtgg tcaactatca atttttttac
    34921 atattgatga aggtgtaaac tataataaaa aggagttaat ggaattatta aaattaattt
    34981 caaaaaaaat atactttttt gaaaagagta cggaaccaac aaaattcaag ttaatttata
    35041 actcgtgggg agcgtatttg ctttactcta ttaagctatt caacccttta cagtatgatt
    35101 tttcaccaaa gtctctagag gtagcgaata caatcgtatg taatgatggt tggatgagtt
    35161 tagtatgcaa ctccaaatta gaacagatca atgatcaaga ttttgatgac atacacttta
    35221 gagtagaata tatggtaaaa gatttagaat atgctaattt ttcagtcttt catgatgaag
    35281 tgaaagaaat aaattattta ttacagcaat atagggattg cttagtaact gatagtggaa
    35341 aagattatac ggtaatagga aagtatgata acttatagga atgacttgct gtctaaagaa
    35401 ttagatatac taatttcatt ttttaaaaaa tgcgaggtag gaaaaatttc actcgttatt
    35461 actggttcct tggcaagagg taatccaaga atcaaggatg ggaaattaga atcggatatt
    35521 gatattctag ttatagtaga cagtattcag caattaatta gtataaaaaa gactttagag
    35581 ggaaggtttc actttgtaca taaaatttct ttgatttttt gtttgaagga aagaataaat
    35641 cgaagtcgtt atcgtggaat tattaatagt attagaagtg tagataatct tttagtagat
    35701 aatctgcata taaaaaatca aataatagaa gctttagact cacctaccaa tattgtggag
    35761 cagactcgct ctatgattca ggaattttgt tattattcat caaaatattt aatttcaaag
    35821 aataattatt tggaattaaa actagaaaag tattggaagg agattgcaac attaaatcat
    35881 atcgataaaa agataaaaca cctagatttt gaaagaatat ttgctgtttt aaaagaacac
    35941 aaaatacaaa ttttggattc aagtgaatat tttttccaaa atgtaaaaac ttctgagaat
    36001 atttatttag agatgaggga tttagtatct ttggaaaatc aaggattaga ctttgaacat
    36061 tgtattttga gcttggggga aagatgataa taaatacatt aggaccaact gcaacagatt
    36121 gttttttatg caataaatcg tataaaatta aaagtagatg tgattgtact gtatgatagt
    36181 tttgatagta tagttaattg ctttgataaa ttaaaagggc aatatatatt attacctgta
    36241 gctttcgaga gtagtattaa aaattatagt tggaaagatt tcaactttga atatcataag
    36301 cggattgaaa ttgtggattc ttttcactct tttactaagg gaatggttct aatcgagaat
    36361 tgtaattata aaattaatag ggcgattatc caacctgcaa ctgagatttt gatgttaaac
    36421 tatttaaaga aaaaaagtat ggatctgagg atagatttta cccatagtaa agttatggca
    36481 aataaaaaat ttctggaaga aggttatcgt ttttcaatag taagtcaaga aacgataatt
    36541 aataatgatg atattattat ttgtgaaact ttctctccag aaatgatttg gtgcttatat
    36601 agagtgaaag gatagaaaat gttttctgaa attattaaga aatatgatat tgttacactg
    36661 aaagatagtg gttttttgag aggtgattgg ttcataggtt cagcgttaat ggctcatgac
    36721 tatgaaagcc ttaaggaagg gatatatttc tatccccagg aaacaatttg gacaagaatc
    36781 ttggatttag a
//
LOCUS       DBEJZJ010000018        33432 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000018 DBEJZJ010000000
VERSION     DBEJZJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.18"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(381..1361)
                     /locus_tag="ACL3R8_001185"
     CDS             complement(381..1361)
                     /locus_tag="ACL3R8_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR1314063.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACL3R8_001186"
     CDS             complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACL3R8_001186"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR1314064.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERETDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMIETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEVWQEDPEWRMIALHLEKEEHLD"
     gene            complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACL3R8_001187"
     CDS             complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACL3R8_001187"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR1314065.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGTHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACL3R8_001188"
     CDS             complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACL3R8_001188"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR1314066.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5211..6242)
                     /locus_tag="ACL3R8_001189"
     CDS             complement(5211..6242)
                     /locus_tag="ACL3R8_001189"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR1314067.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6244..7275)
                     /locus_tag="ACL3R8_001190"
     CDS             complement(6244..7275)
                     /locus_tag="ACL3R8_001190"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR1314068.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACL3R8_001191"
     CDS             complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACL3R8_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR1314069.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKKRYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10063..10302)
                     /locus_tag="ACL3R8_001192"
     CDS             complement(10063..10302)
                     /locus_tag="ACL3R8_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314070.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLVFGILSILMALLSKKVSLFVFGLICCLSL"
     gene            complement(10330..10962)
                     /locus_tag="ACL3R8_001193"
     CDS             complement(10330..10962)
                     /locus_tag="ACL3R8_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314071.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10966..11607)
                     /locus_tag="ACL3R8_001194"
     CDS             complement(10966..11607)
                     /locus_tag="ACL3R8_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314072.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11600..12391)
                     /locus_tag="ACL3R8_001195"
     CDS             complement(11600..12391)
                     /locus_tag="ACL3R8_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314073.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12576..12911)
                     /locus_tag="ACL3R8_001196"
     CDS             complement(12576..12911)
                     /locus_tag="ACL3R8_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314074.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            complement(13051..13386)
                     /locus_tag="ACL3R8_001197"
     CDS             complement(13051..13386)
                     /locus_tag="ACL3R8_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314075.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACL3R8_001198"
     CDS             complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACL3R8_001198"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR1314076.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14801..15514)
                     /locus_tag="ACL3R8_001199"
     CDS             complement(14801..15514)
                     /locus_tag="ACL3R8_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR1314077.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACL3R8_001200"
     CDS             complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACL3R8_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR1314078.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16408..17577)
                     /locus_tag="ACL3R8_001201"
     CDS             complement(16408..17577)
                     /locus_tag="ACL3R8_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR1314079.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRDR
                     GQKAKTQKQNQTAPEKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACL3R8_001202"
     CDS             complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACL3R8_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR1314080.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18191..18556
                     /locus_tag="ACL3R8_001203"
     CDS             18191..18556
                     /locus_tag="ACL3R8_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1314081.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18561..19256
                     /locus_tag="ACL3R8_001204"
     CDS             18561..19256
                     /locus_tag="ACL3R8_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314082.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19273..20040
                     /locus_tag="ACL3R8_001205"
     CDS             19273..20040
                     /locus_tag="ACL3R8_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314083.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20393..21592)
                     /locus_tag="ACL3R8_001206"
     CDS             complement(20393..21592)
                     /locus_tag="ACL3R8_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314084.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVEVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21589..22482)
                     /locus_tag="ACL3R8_001207"
     CDS             complement(21589..22482)
                     /locus_tag="ACL3R8_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314085.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22605..22796
                     /locus_tag="ACL3R8_001208"
     CDS             22605..22796
                     /locus_tag="ACL3R8_001208"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314086.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23189..23377
                     /locus_tag="ACL3R8_001209"
                     /pseudo
     CDS             23189..23377
                     /locus_tag="ACL3R8_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23792..24409
                     /locus_tag="ACL3R8_001210"
     CDS             23792..24409
                     /locus_tag="ACL3R8_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR1314087.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24729..25616)
                     /gene="scrK"
                     /locus_tag="ACL3R8_001211"
     CDS             complement(24729..25616)
                     /gene="scrK"
                     /locus_tag="ACL3R8_001211"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR1314088.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25765..27702)
                     /locus_tag="ACL3R8_001212"
     CDS             complement(25765..27702)
                     /locus_tag="ACL3R8_001212"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR1314089.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLIGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGNAVIEVKI"
     gene            28078..29532
                     /locus_tag="ACL3R8_001213"
     CDS             28078..29532
                     /locus_tag="ACL3R8_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR1314090.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQNLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29513..30478
                     /locus_tag="ACL3R8_001214"
     CDS             29513..30478
                     /locus_tag="ACL3R8_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1314091.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30513..31787)
                     /locus_tag="ACL3R8_001215"
     CDS             complement(30513..31787)
                     /locus_tag="ACL3R8_001215"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR1314092.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31787..32959)
                     /locus_tag="ACL3R8_001216"
     CDS             complement(31787..32959)
                     /locus_tag="ACL3R8_001216"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR1314093.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLNKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33090..33338)
                     /locus_tag="ACL3R8_001217"
     CDS             complement(33090..33338)
                     /locus_tag="ACL3R8_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314094.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9811 a         7447 c         6311 g         9863 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgtttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gaccgatttg tcctgttctt atttcatttt actatatttc catgataaaa
      301 cgcatagtat aaagttttct taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1561 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1621 gactttagta taagagccaa acctaaaaac tagcttaagt tttccttaga gaaagcttaa
     1681 tccagatgtt cttccttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     1741 caaacttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     1801 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     1861 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     1921 atcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     1981 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagttg actgagaccg
     2041 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     2101 ataaccgtcg tcgaaaccag aatatccgtc tctctctcct tgaaatcctg catgatctgg
     2161 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     2221 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2281 tcaatcaaag gagagatgac atagacttgg gaaccttttt gaatttcccc ctctaaccaa
     2341 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2401 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2461 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     2521 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     2581 gcatactcca ccccatcttg tatcagagcg tgagttccta taatcaaatc agcctcaccc
     2641 ttggcaatgg tctccaagac ctctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     2701 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     2761 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     2821 ccagcgacta ccgtttttcc actccccaca tccccttgta ggagacgatt catgtggtgg
     2881 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     2941 aaaggaagac ttactttaac tgctgtcact ttttcctgag accaattcag aaccagacca
     3001 cttccctgaa ctctattttc agacttgagc atctgcagct gcatttggaa ataaaagagt
     3061 tcctcaaact ttatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     3121 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     3181 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttaacc
     3241 agactggcct gactgattcc ctgagccaga cgataaacag gctggaggtc atcttctacc
     3301 tgagccagaa ccttcatccc attcagacta gccttagcgc ggtcccattt tccaaagaca
     3361 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3421 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3481 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttcc
     3541 agctccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     3601 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     3661 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     3721 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt tacgcggtag
     3781 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     3841 gttcctagcg gataaagctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     3901 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     3961 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     4021 gctccatagc ccatgcaagc tcctgctgga actgtcttga catgaaccag agcagactcc
     4081 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     4141 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     4201 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4261 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4321 tgggtaaaga ttccttcaac acgaacaccg tgttgttgta gcaaatcttg agcctgctca
     4381 acctcactgg cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4441 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4501 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     4561 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     4621 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatga
     4681 ccataagcat tggccttgac cacagcccac ttgagcgttc cttgagggat atgagtcccc
     4741 atttgctgaa tattttgtcg aatagctccc agatgaatca gaaccttggt tggtctatgt
     4801 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     4861 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     4921 ttcattgttc aatacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     4981 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     5041 tttgagactg gtgaagcgct ccatttcctg agcagtcagt acacgcttag caaatccttc
     5101 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     5161 tatcattttc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     5221 aaggtaacat aaatctcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5281 gtaatagagc aaccaaagat ctctggttgg ttttgacgac catctgctag gtaagattca
     5341 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5401 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5461 atgaggataa aaggattttc aagtcccatg gtttcatagc gttcaatggc ttggagtagg
     5521 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     5581 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     5641 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     5701 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     5761 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     5821 taaagcatct catctgccgt tgttaaacca gtctctgtaa tcacgcggta gtgcaactgg
     5881 cgcacagcct gcaagccgtt aatcaggctt ggagccttag aagtatctgg ctggtgaacc
     5941 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     6001 aaaatcttat ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     6061 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     6121 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     6181 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6241 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6301 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6361 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6421 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6481 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     6541 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     6601 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     6661 aaggaaactt tgtttgtttt gagcagcata aattccatta aacatgacat tgagatttcc
     6721 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     6781 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     6841 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     6901 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     6961 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     7021 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     7081 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     7141 ctgatcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     7201 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7261 tgctgtaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7321 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7381 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7441 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7501 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     7561 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     7621 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     7681 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     7741 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     7801 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     7861 gtaatagaat cttcaggaag caagttgtac ttagcaaagt tcaaaattgc ctctagtttt
     7921 tcatcttgtt tagcacgcgc atgaccgtca acgacacgtt caatcgtgcg tttgatcata
     7981 gactgaattt caggtgccaa gtcacgatct gcagtgatga catcgtaacg ttgagcatag
     8041 ataatctcac gttgttcacg catgacatca tcgtattgaa ggacttgttt acgggtatcg
     8101 tagttatttc cttcgacacg tttctgagct gcttcaacct gacgcgtcaa catgcgagac
     8161 tcaatcgcct cttcagacat gttgagacgt tcaaagattc ccttcaagcg ttcagaacca
     8221 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8281 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8341 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8401 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8461 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcgacc
     8521 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     8581 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttcgatactt
     8641 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     8701 acacgaatgt tgtagatttc acggaattct tcttcctcag tcttacctgt acccgtcata
     8761 ccagacaatt tcttgtacat acggaagagg ttttggtacg tgattgaggc agatgtcttg
     8821 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     8881 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     8941 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     9001 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     9061 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     9121 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     9181 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9241 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaacg
     9301 accatgttgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9361 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9421 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caggtattca
     9481 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
     9541 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
     9601 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
     9661 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
     9721 ttcttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
     9781 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
     9841 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
     9901 agaatgttcc tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
     9961 gaaaaggaaa aagaggttag ttttcaagct aacctctccg acttttatga ctgtttaatt
    10021 gccaaaaatt ggcaaaatgg caaatgtgat aaataagtta attcaaagag aaagacagca
    10081 aatcagtcca aaaacaaaga gactgacttt cttggacagc aaggccatca aaatggacag
    10141 aattccaaaa actagcaaga ttttctgtat gatgaagatg tcaatcctta cccccagaat
    10201 cgctctatcc caagggataa agaagaaaga cagccagatc agcagaacta aaccaatata
    10261 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc acaagccatc tcctaggatt
    10321 gtatatcctt tacatttgta tatgtccatt ttcgacaact aatacatctg tacaaaggtc
    10381 tgaaatatct tccgatatgt gcgacgtcag gataaccaga ccattttctt ttttcaggta
    10441 agataaaatg acctgtttgg ttaacctcac actcttctca tccaaagcat tcataggttc
    10501 atcgagaaag agtatagaag gagaggaaat aaaggcttga atcaaggcca ttttttgctt
    10561 tgttcccaag gataaatgcc ggtattcaac gtcttcaaat tcctgtaaat catagtattg
    10621 aatccaatag gcaattcttt tttccgtaac tttagatgaa aaatacctta acagttccaa
    10681 attttctctc agggataaat gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc
    10741 ctgaatataa tgatttttta tcccgtaaac tttaccatct tgaagaactt ttcctttgtc
    10801 aagcttaata taaccagcaa gtacctttaa aagaaccgtc ttgccagatc cattatcacc
    10861 tttaagtcca taaatttttc ctgattgaaa caccaaattc aactgattta aaataggtct
    10921 tttcccataa attttctgtc catttataat ttcaagtttc atcgtttatc ctttcttaaa
    10981 tttctcttcc aagcgactaa caatcaacat aactaataag cttaagagta gtaaatacac
    11041 tgttacaata tgatccatca tccattcttg tcccacaaat gctaaaaaat agagaaaaaa
    11101 ggaaaaacca gcgcccgcac taatcagtgc tatcagataa gacagtagta agtacaacat
    11161 cattaactga gcaagtaaaa agaaaagtgc gactgttttg aaatgaattc ctagcggaag
    11221 taaaccaagg aaccagacaa gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg
    11281 tttccttgta taatcgaaaa aggagcttga ttgatagcga atcaagtgat ggtaatggtc
    11341 tgccaaatca ctttcaagta aaatgacaga gagccatcct accatgaaaa gcgaaaggtt
    11401 taacaagagt ttggggattt ctaaattcgc ttcagaatag tcattatagg aaaagattga
    11461 aatcaattct ctcttgaaaa agataacagc atcctgcttt tgaaccgctg ttgacaatag
    11521 atagtttatc aaaatcatca tcagaactat acgaagtagt aaaacgatct ttctctttag
    11581 ccaaatattg ttaaaattct taaacattat cttcatattt ttcaagcacc atataaggga
    11641 caatataaag gatataagga gtaaagagtt tcatcaaact tacatcccca tagctagctt
    11701 gcatcaaact cgtcatagga accatatagt aaggcaaggc actatagagc agcatagaac
    11761 caagccaaag aaacatcaaa taggtgattg ccgaacgagt cacattcccc acataatcaa
    11821 ctatttgtaa aaaatagatt gcattgatga aaataccgat tagtaggaca caagtaaaga
    11881 acaaatagct ttttatctct ccatctagga gtctttgtaa accacttcca tcagaaaata
    11941 gagaattcca tccaagagga gaaaaagtcc caaagaaata ggttataatt gcaattatca
    12001 gcacagtcac taaatatatc aaacaaggga tacttgcaac ttgcaaagtc aactttcttt
    12061 ttaacccttg ataactcact tctcttccaa tactcaatcg taaaacttta tttttcagct
    12121 caatatattg aaaacctagc aaaacaatga tgattggaat aataaatgat tgataaaaac
    12181 ctagattgaa ctggagaata cgaaaatcta atgctgattt taataagtca tttttaattg
    12241 cttgtccatc gaatttagct agatcgggcg catgaatatc aaaaaagaaa taagtcatca
    12301 aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag caagacataa acaaatttat
    12361 gccttgccaa agttaagaga ggaatcttca taagccacct cctacaaata gaaagtaata
    12421 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaagttg ctcaaagcac
    12481 tgctttgagg ttgtagataa gactgacgaa gtcagttaca tatataatcc aaggcgacgt
    12541 tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat gccttacgcc tttagacttc
    12601 cctagttccc gtctcaagtc aagcattttt ttgaaacaga tatagtctaa ccagtcacta
    12661 gcaaaagcga taagtagtaa taatagccaa ataccccata acttgatatc tgtcaaattt
    12721 ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc aagcaaggct aaaaagagaa
    12781 tagagggtga tgtaaatcca gtaaaaatag taaaaaattg ggaaaaattt actttctcta
    12841 ttatccttgt caatccagct gaaaaagtaa aaacagggta ataagattat cattttaaac
    12901 aagtgttcca tcacaagcct ccttttttaa attgttttct ttagtttcgt tctattaaat
    12961 attattatca atataaacct tggaatagcg tgtaataaat gattttagag gtaccataag
    13021 ccacctccta caaatagaaa ccgatataaa tcaatgcctt ccacccttag acttccctag
    13081 ttcctgtctc aagcgaaaca tttctttgaa acaggaataa gttaaccaat tcataccaat
    13141 agctagcaga ataaaaagaa accaaatgcc ccataacttg atatctgtca catttctcaa
    13201 gacggtattg aaaaacagaa ctgaaacaac tgtccaagca aggctaaaaa gagaatagaa
    13261 ggggatgtaa aaccagtaaa aataataaaa aattggaaaa aacttactat ttctgttggc
    13321 cttttcaatc cagttatcaa aataaaagta cggtgctaaa agtaagaatt taaacaaatg
    13381 ttccatcacc gacatcaccc tccttctttt gatagcgttt tctattattt tattatatca
    13441 aaaaaatccg gaactgtcat tccagattct acttttttat ttgcgttttc ttgcgatgag
    13501 atgaatcggt gttccctcaa aaacaaaggc cttgcggatt tgattttcca agaaacgcag
    13561 gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg acaaaggttg gtggtttggt
    13621 tgccacttgg gtcgcataga aaatcttgag acgttttcct ttgtctgtcg gtgttgggtt
    13681 gatggcaatg gcatccatga tgacatcgtt caagacagct gatggaatac gtgtattttg
    13741 actttcgctg atttgcttaa tcatctcagg aagtttgtgg agacgttgct tggttaaagc
    13801 tgatacaaag ataatcggtg cgtaaggcag gtattggaac tgctcacgga tatcttcttc
    13861 ccagtttttc atagtgtggt tatctttttc aagcgtatcc cacttgttga ccacgataat
    13921 catcccttta ccagcttcat gggcaaatcc tgcgatacgc ttgtcgtact cacgaatgcc
    13981 ttcttccgca ttgatgacca tcaagaccac atctgaacgg tcaatagcac gcatggcacg
    14041 cataacagag tatttctcag tattttcata aaccttacca gacttacgca taccagccgt
    14101 atcaatcatg gtaaactctt gaccatctgt atctgtaaag tgggtatcaa tggcatcacg
    14161 agttgttcca gcaacaggac tagcaataac acggtcttcg cccaagatag cattgatcaa
    14221 gcttgatttt ccaacgtttg gacgaccaat caggctaaac ttaatgacat ctggattttc
    14281 ttcttcatat tcatttggaa ggttttccac aatcgcatct agtacatccc ctgtaccgat
    14341 accatggaca gatgagatag gcagtggttc acccaaaccg agggcataga aatcatagat
    14401 atcatttcgc atctcagggt tgtccacctt gttaactgcg aggataactg gtttgtgggt
    14461 cttataaagc ttacgggcta cgtattcgtc tgcatcggta attccttcct taccggacac
    14521 gacaaagacg ataacatctg cttcttccat ggcaatttct gcctggtgct tgatttgttc
    14581 catgaaagga gcatcgacat catcaattcc tcctgtatca atcatgctaa aagaacgatt
    14641 gagccactca cccgttgcat aaatacggtc acgtgtcact ccttcgacat cttctacaat
    14701 ggagattcgc tcaccagcga tccgattaaa tagggttgat ttcccaacat tgggacgtcc
    14761 tacaatggca atagttggta gggccataat ttctcacttt ctacaataat ttcttctgtt
    14821 caagattttt tctagttgag cttggttcag cttgaccaaa ctgttctgct aggcgctgac
    14881 tccagcttgt ggtcgcacgc gccccagcat agtcagcctg aacacggtca taagcttgga
    14941 ttgcctcagt tgactgttct tggtattctt cctcaaagac aacattctct agtggcagtc
    15001 tcggtttcat atcatgatgt tgatttggca cacccagtgc catcccaaag acagaatagg
    15061 tgtagtcagg caggttaaag agctctgcca cttcttcaga cttgtatcga accaaaccga
    15121 taatcacacc accatagccc aagctttcag ctgccaacaa ggcgttttgt ccagcaagag
    15181 ctgcatcgac cgaactaatc aagagacctt ccacaccttg gggttggaag gtgtcggtat
    15241 gaagtcgggc tcccttttct gctcggttca aatctccgac aaagagaagg aaaacagcag
    15301 actggcgaat ggcttcttga ggtaccaatt catacaaggc atctttcttc tcttgacttc
    15361 gtaccacaat cacagagtag gattggaaat tcttccaaga tgatgccatc tgggctgctg
    15421 tcaaaatctc atttaagtct acttggggaa tttcttgctc tttaaacctg cgcactgaag
    15481 tatgagcctt catcaattta atggtttctg tcatcgacgg tttactcctt ctaaacgagt
    15541 ctcctcagcc aaataacgga tgcgttccat gacccgtctg gcttcccagg tttcgtcatt
    15601 tccatgtttc actttcgcaa aatgcttctc caaatcttca aagttgaagt tggatgtgaa
    15661 aaaggtcggt aaattttcct gcatccgata ttggagaatg acctgcagga tttcgtcacg
    15721 cacccaaacg gttgattgct cggcgccaat atcatctaaa atcaggacct cagacagctt
    15781 aatctcatcc accaaggtct taacattgcc atcactgata gcatttttga catcaatgac
    15841 aaagctagga tagtggagga gagttgatga aacaccacgt ttttctgata aatcatgagc
    15901 taaggccgcc accatgaaac ttttacccac accaaagtct ccatataagt aaagaccttt
    15961 tcgaatagct ggatattgct ccacgaaggc tagtagcttt tcaaaaactg gtaagcgccc
    16021 caaatcatcc aagtcaactt gagccaaact agctttcttg agactggctg gtagattgat
    16081 taacttgaga cggttcttaa tagccgcttc tttttcagcc gcgattagct caggagtttc
    16141 ttcatatgaa acatctgcat agccatgatt cttaaccaaa atcggcttgt agcctttggc
    16201 aatataatcc gtatccccac ggagaaactt gtcacgctcg gtgatgtact gattaaactt
    16261 ggagatactg cgatttaatt cctctggagt taaggattct tgctggataa aggccgcaac
    16321 atcagggtcc ttcatgattt tctggaccaa atcttgataa taaaaacggc tgggttgacg
    16381 tttgagtacg tctccgacac tttccatcta atctcctcct ttttctaatc gagctaatag
    16441 ttcttgcttc ttacgttcta gttccagacg agtttcctcg ctggtttcat tcttatattc
    16501 aggattactc catttaggaa cattggtttt ttctggggca gtctgattct gtttttgtgt
    16561 ttttgctttc tgccctcgat cacgaattcg taaaacggcc tcttctgccg aatgaatctt
    16621 ttgataggca tagtcattgg ctaccttcat ggcatatttc tcattgatat ttgccgaatc
    16681 caccttatta aaggtcaata agagaataat attgatgact tcgtccagta agcccaagcc
    16741 agccatctgt tgcaagagtt ctctttctgt ttgggtaatg gttcccttgc gtgtttgctt
    16801 gatttctgct aagaactgca gggcagtttt acttttagct tctttgataa tggtcgcttc
    16861 cttaagacta aagtcagagg aaactggttt ttgagcaatt ttttcacgca tgcgtttggt
    16921 tgaaataacc tgggaaacag ctgttgactt ggccaattga taggtttcaa accaagtcca
    16981 tttcttctcc tcggcaatag caaagaggtt taagacatcg gactgctcat ccgcaaaacg
    17041 aagtccatct cgagccatca gctggcgaaa atgttccaag tcaaaatcat tggccacttt
    17101 cttcttgaga ccaaggtctt cttgactgcc tagttctgcc aattctggaa agacttgatt
    17161 gagtgagaca ggtatttctt caccatcagc actttcaact ttcaaatcct ccacagctac
    17221 atcgccaatc tttttctcta agagtctgcg ataaacagga tgccccaaga agtcttgact
    17281 agatagagga gcatggaggg ctagctgata aacatcaccc ttttgataga gggtcaagag
    17341 attaaaagca gataagattt tcaatgattt tatcagtcta tccatcccaa agttgagatg
    17401 gttgagaatg cttgaaaaaa gatattcctt tctaccatta tcccaaaaac tgattgtata
    17461 aagataaagg ctcagtgcct cctgaccgat aatcgggagg tagcactgta ccagagatga
    17521 ggtatcttgc gacacccgat tattctttag ataagaaaaa cggtcaattg gcttcattta
    17581 tctttccttt ttctttttag aggactgggt gatttgttgg agcaagctct ctaactcact
    17641 gacatcctta aaactacgat agacactagc aaaacgtaca taggtaatct cgtccaattc
    17701 agccaactcc tccatgacga gtgaaccaat gtcctcactt tgaatttcat tttcatttcg
    17761 accacggagt ttctgttcga tacgattgac taccatgttg atttcatcac ttgacacagg
    17821 acgtttctgg gctgagcgga taatcccatt aaagatttta tctctggaga attgttcccg
    17881 tgtgccatct tttttaacaa ccactaaggt tctttcttct actcgttcgt aggttgtaaa
    17941 acggtgttgg cattcgtcgc actcacgtct tctacgaatg gtgttccctt cttctgcttg
    18001 gcgactatcg ataacacttg acttggtagc cccacatttt ggacaacgca tcctttccct
    18061 ccttatcgtt ttcttttcat tataccattt tttaagcgat tcccaaaaca attcttcttt
    18121 ttgcttgaca agttttttgt tttgttgtat tatttaatta agacaacaag gtaaaagaaa
    18181 ggagactaag atgtcctgga catttgacaa caaaaaaccc atctatttac agattatgga
    18241 gaaaatcaag cttcagattg tttcccatac actggaaccc aatcaacaac ttccaaccgt
    18301 gagggagcta gctagcgagg ctggtgtcaa tcccaatacc atccaaagag ccttatcaga
    18361 ccttgaacga gaaggatttg tctacagcaa gcgaacaact ggacgatttg tgactaagga
    18421 taaggagcta atcgcccagt cacgcaaaca attatcagaa gaagaattgg aacacttcgt
    18481 ttcctccatg acccattttg gctatgaaaa agaagaacta ccaggcgtag tcagtgatta
    18541 tattaaagga gtttaagcct atgtcattac tagcatttga aaatgtatcc aaatcatatg
    18601 gagcaacacc agcccttgaa aatgtttctc ttgacattcc agctggaaaa attgtcggcc
    18661 ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa actaattaat ggcctcttac
    18721 aaccagatca aggacgtgtc ctcatcaacg acatggaccc aagcccagca accaaggccg
    18781 ttgtagctta tttgcctgat acgacctatc tcaatgagca aatgaaggtc aaagaagccc
    18841 taacctactt caagaccttc tataaagatt tcaatcttga acgcgctcat catctacttg
    18901 cagacctggg cattgatgaa aatagtcgtc tcaagaaact atcaaaagga aacaaagaaa
    18961 aggttcaact gattttggtt atgagccgtg atgctcgtct ctatgttttg gatgaaccca
    19021 ttggtggggt ggatccagca gcccgtgctt atatcctcaa taccattatc aacaactact
    19081 caccaacttc taccgttttg atttctaccc acttgatttc tgatatcgag ccaatcttgg
    19141 atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca aggaaatgta gatgatattc
    19201 gctacgagtc aggtgaatcc attgaccaac tcttccgtca ggaatttaag gcctaagcaa
    19261 aggagattat ttatgttttg gaatttagtt cactacgaat ttaaaaatgt taacaagtgg
    19321 tatttagccc tctacgcagc cgtgctagtc ctttctgccc tcatcggaat acagacacaa
    19381 ggctttaaaa atctacctta ccaagaaagt caggctacta tgctactttt tctagctaca
    19441 gtctttggtg gcttgatgct tacacttgcg atttcaacca ttttcttgat tattaaacgc
    19501 ttcaaaggta gtgtctacga ccgacaaggc tatctgactt tgaccttgcc agtttctgaa
    19561 caccatatca tcacagccaa actaatcggt gcctttatct ggtcattgat tagcaccgct
    19621 gtattggctc taagtgctgt tattattctg gctttaacag ctccagaatg gattcctctt
    19681 tcttatgtga ttacatttgt agaaacacat ctccctcaga tctttcttac aggtatatcc
    19741 ttcctactaa ataccatttc aggaatcctc tgcatctacc tggctatttc cattggacag
    19801 cttttcaatg aataccgtac agcactcgct gttgcagcct acattggtat ccaaatcgtc
    19861 attggattta ttgaactttt cttcaatctt agttctaatt tctatgtcaa ttcactggta
    19921 ggactcaatg accatttcta tatgggagca ggtatagcca ttgttaaaga actcatattc
    19981 atagctatct tttatctcgg aacctactac atcttgagaa ataaggttaa tttgctttaa
    20041 ataattttta cctagatatg taacatactc atagaacaaa agagaccagg caaaaagtct
    20101 ttaaaattag aaaacgcata gtatcaagtg ttaaaaatcc ttgatattat gcgttttttg
    20161 tgagttgact tatttccttt cactatatcg caaaatgaaa taagaacgga acgatgggat
    20221 tttggaattc aaatcaattt gtaagaatgt tttagaagta atattatcct attccagatt
    20281 cagttcacta tacaattgag ttttcaagca acttgtttac ataatgtgta cataattagg
    20341 ttcgtgattc cacccttttc acctttaaaa acctcgcttt cgcaaggctc ttctatttat
    20401 aagataaggc acgtttaaag gttttccaaa tccctaaatc atccgtttga agaacgagac
    20461 tagcatacat gcgtccgata aatcctgttg ctaccaccgc aaaaatcact gtaatagcaa
    20521 gtgaaatcca tgcttccgct ccccccgcat agccattaat cgttcgaaac ggcataaaga
    20581 aggtcgaaat aaagggaata taagaaccaa tcttcaagag gagattgtca ccagctgcac
    20641 ctagagctgt cactccaaaa aaaccaccca taatcaaaat catcaaaggc gacaaggctt
    20701 tccctgagtc ctcaggacga gaaaccatag atcctaggaa ggctgccaag actacataca
    20761 tgaaaagact gatcaaaata aagagcaggg tattcagtga gatagcatct cccaagtgat
    20821 ccaaaatacc agactgagcc aagaatggca aatctttaaa gagcaaaacg gcagccagac
    20881 cacctacaac atagatccca atatgcgtta aaatcactag aaacagagcc atcatccgcg
    20941 catagaaata gtgacttgcc cttatgctag aaaaaacgac ttccataatt ttggtgcctt
    21001 tttcactggc aacttcctga gctgttacac ccgcataggt aatcagaatc atataaagaa
    21061 agaatcctaa ggcacctgct gcaattgttt gaataaactt tttattttcc ttggcttcat
    21121 caatcttttc tgtgaattga attgtctgcg ctaagcgttt ttcctgctct tgagacaagg
    21181 aagcagttga acgattaagc tgattttgca gttcattgag tgtacctgta acctcaaatt
    21241 taattccatt ttcaagcgat gtttcgccat gataaactgc ctttagaaca ctatcttctt
    21301 gatcaatggt caaataacct tttaattttt cttctttaat tgcttctttg gcacttgctt
    21361 cgtctttata gtcgaagtta acaccattta cattcttcag tccttctgct acagatggca
    21421 ctgttgtcac tacttccact ttattatttt tagccataga agaaccttgg agatgcccaa
    21481 ttcctacaga gattcctaaa aagaggaacg gcgaaatcac cataaagaag aaactccatg
    21541 actcgacatg tcgaagatag gtttccttga ttacaaccca catatttctc atacttccac
    21601 tcctgattct agtttaaaga tttcatcgat agttggcgct tgttggtcaa atgttgcgat
    21661 atattgacct tgagtcaaga ttgggaagag ttcccttcca gcgctctcat cctccaaaat
    21721 caatttccaa ctgccttgtt tggtcaagct cacctgtttg acatgaggaa gattttccaa
    21781 ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt ttcccgtatt gattgcggac
    21841 atcctgaact ggtccgtgca agaccacacg gccatctcgg atcatcagaa tatcgtcaca
    21901 aagttcctca acattggtca tgacatggtc agaaaagata atggttgctc cgcgctcttt
    21961 ttcctgaaaa atgacttgtt tgagcaattc tgtattaact gggtccaatc cactaaaagg
    22021 ctcatccaag ataatcaggt ctggttcatg aatcagagta ataatgagct gaatcttctg
    22081 ctgatttcct tttgacagac tcttgatttt atctgtcagc tttcctttca cttccaacct
    22141 cttcatccat tgagggagtt tttctttgac ttctttggca tccatgcctt ttagagtcgc
    22201 caagtagcga acttgttcaa gaactgtcaa tttaggcatg agactgcgtt cttcaggcag
    22261 ataaccaatc cgagcatagg tctcctgacg aatatcctga ccatctagac cgatttctcc
    22321 ctgatattct aggaatttca aaatactatg gaaaatcgtt gtttttccag caccattttt
    22381 tccgactagt cccaaaatac gacctggtcg cgcttgaaag tcaataccaa acaaaacttg
    22441 cttggagcca aaacttttct ctagacttct tacttctagc atctttcacc tccgaaattt
    22501 cttgcactca ttatactcct ttttgatagc ctttacaatg ttttttgtcc atttttagaa
    22561 gactattgct gtgtaaaata tggcctggag cacttttata ctcaatgaaa agcaaagagc
    22621 aaactagaaa gctagccgta ggctgctcaa agtacagctt tgaggttgca gataaaactg
    22681 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaact
    22741 atatctacgg caaggcgaag ctgacgtggt ttgaagagat tttcgaagag tattagtgat
    22801 aaatccatta tacagtagca aacttaattt ataccttccg ctcctcaact gtctattttt
    22861 aatcctgaat tgttatttga gtaactcctt tttcctcata aagttttctt cctctaaaac
    22921 ttctggaaaa aagcgaatag tttcagataa catttttata aggaacaagt tcatctgtca
    22981 tttcaagaag gagtaatcct ttatctacta atggacggaa cggaattcaa ccgcttgtcc
    23041 gatatgtttt ctaaggatta tatagtaaaa tgaaataaga acaggacaaa ttgatcagga
    23101 cagtcaaatt gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
    23161 tgctatatct attatgcaca ccactatagg atctaataaa aatcacaaca agttcattca
    23221 tagatggtta cctcagggaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
    23281 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
    23341 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
    23401 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
    23461 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
    23521 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
    23581 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattc
    23641 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
    23701 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
    23761 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
    23821 ttctcccctt ctgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
    23881 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
    23941 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
    24001 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
    24061 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
    24121 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
    24181 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
    24241 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
    24301 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
    24361 tacctacggt ctgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
    24421 tccgtttggt ttcccaagtg gatttttaaa gcgtagatta actatagctt gatactaaat
    24481 atactttggt atggaaatca tgcatatttt tcgatagtga ggcgaggact tacctagcct
    24541 ttccgccgtg atagaaacac ctgaaatcta atggtttcag gtattcggaa actttgagac
    24601 actaggctca aagtttaggt atggaatttc gaagaaagtc gctaccgtcc gtaatcactt
    24661 aaggaaaggc tcaaaaatat tgttttcaac cacaaaatcc gtttggtttc ccaagcggat
    24721 tttgtgcttt attttgaaac ttcttttgca agaacaaagt tcccaagtgt ggcagaacca
    24781 tttcctgcga ctgctggcgt cacgatatag tcacgcacat ctggtactgg taggtaacca
    24841 ttaagaagag atgtaaattt ctcacggaca cggtccagca tatgttgttg agccatgacc
    24901 cctccaccaa agacaatcac gtctgggcgg aaagtcactg tcgcattaac cgcagcttga
    24961 gcgatatagt aggcttgaac atcccaaaca gggttgttga gttcaatagt ttccccacgt
    25021 acacctgtac gagcttccaa acttggacca gctgcataac cttctagaca tcccttatgg
    25081 aaaggacaaa cacccttaaa ctctttttca atatccattg ggtgtctagc aacataataa
    25141 tgacccattt cagggtgacc cacaccaccg ataaactcac cacgttggat gacgcctgca
    25201 ccgatacctg taccgattgt gtagtaaacc aagttttcga tacgaccacc agcattgtta
    25261 cgggcaacca tttcaccgta agcagagctg tttacgtctg ttgtgaagta cattggcacg
    25321 tttagggcgc gacgaagggc accaagcaag tccacatttg cccagtttgg ttttggagtc
    25381 gtcgtgataa agccataagt ttttgagttt ttgtcaatat caatcggccc aaatgaacca
    25441 actgcaagac cagcaaggtt atcgaatttt gagaagaact caatggtttt atcgattgtt
    25501 tcgattggag ttgttgttgg aaattgtgtt ttttctacaa cgttaaagtt ttcatcaccg
    25561 acagcacaga caaactttgt accgcccgct tccaagcttc catataattt tgtcatgata
    25621 aacctcttgt ttttattttc tttattatag catacttcga aagtctaaat gtctctattt
    25681 tttagatttt cctctgtaaa tcttactatc taataaaaac gaacaaacat gtcatttgtt
    25741 cgttttcaca ttagagagga ttgattagat tttcacttcg atcacagcat tccccttcgc
    25801 aactgaacct gttgcgactg gagctactga agcgtagtca gctgtatttg taacgataac
    25861 cattgttgta tcatcaagtc cagctgcagc gattttgttt gagtcaaatg ttccaagaac
    25921 atcgccagct ttcaccttat taccttgagc aacttttgct tcaaaaccgt caccgttcat
    25981 agatacagtg tcaataccaa cgtgaatcaa aacttcagca ccatttcttg ttttcaaacc
    26041 aaaagcgtgc cctgttggaa aggcaattga aacttcagca tcagctggtg catagaccac
    26101 gccttggctt ggtttcacag cgataccttg tcccatagct ccacttgaga agactgggtc
    26161 attgacatca gcaagagcga caacatcacc aacgatagga gttacaagtg tttcattttg
    26221 aagagtatca gtctcttcca ctactggtgc ttctactgta ggttctgtaa ctgtttctgc
    26281 ggttgctgtg gcagcttcat cagcaaagac actagctgct tttgttttcc cgtagaaata
    26341 agtgaaagca aaggcggcaa caaaggacat aatttccgca attatataca tagggattga
    26401 accagcctta atagaaagga atccaataaa tccagccgct cccaatgaaa ctgcaataac
    26461 gtgagttaaa cctgctacaa aggcaccaat tgctgaacca gcaagggcgc agaagaatgg
    26521 gaatttgtat ttcaagttta ccccaaagag agcaggttct gtaataccaa ggaaggcaga
    26581 aacagcagcc gaactggaca atccttttgt tttagcattt tttgtcaaga agtagactgc
    26641 aagagtagcc gcaccttgtg ctacgtttgc cattgaagca acaacaaaga tgtagtctcc
    26701 aaatccagta ccgttattat tgtatgcaga caacaattgt gtttcgattg ctgggaatga
    26761 ttggtgaaga cccgtcataa cgattaatga gtaagttcca ccaaatagcc ccataccaaa
    26821 ggcacctgtt gtgttgtaca accatacaat cgcatttgta atcgcatcag acacaaccaa
    26881 cataacagga ccgataactg taaaggtaag gaatcctgta atcatcactg ataaaagcgg
    26941 tgtaaaagtg aagtcaactg cagatggcaa tttcttgtgg aagaattttt ctaaattagc
    27001 taacaaccag actgcaacaa ggactggaat aacctgataa gcatagtttg tttgtgtaac
    27061 atggaaacct aagatgtccc agaaggcttc tttaccaccc aaatctggag tggtcataat
    27121 cataccgatt gccgcaccaa ggaattggtt tgctccaaag cgcttggctg ctgaaatacc
    27181 aatcaaaaca gggaggaaca taaatggagc agcagacatc aattgaatca tagctgagaa
    27241 gcctttgata gcaggataca tatcttcaat tgattgaggt ccaaacaaat ctggtgatgt
    27301 caagaagttc cgtaaagcca tcaagagacc acctgcaact aaggcaggga taataggaac
    27361 aaaaatgtct gacaaaagtt taatcaagtc catcaatgga ttgaactttt tgtctttatt
    27421 agcaatctct ttcaaatcat ctgtcgaaac ttctttcaaa ccagttttct taataatttc
    27481 cgcatatacg aagttaacat caccaggacc aatgataatt tgatattgtc cgttagtgct
    27541 aaaagtcccc ttgacatccg cattattatc cagagctgct tgattcactt ttgcttcgtc
    27601 tttcaatacc aagcgaagac gtgtcgcaca gtgagctgca gctacaagat tatccttacc
    27661 gacagcctca atgacctcgg cagcaacttt actataatcc atagcaaaaa tctccttata
    27721 taacattttg ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat
    27781 gttttaaaaa tatgtcaagc gttttgcaga aaaaatatta tatctactta gtgggcaagc
    27841 tttagattga ttgtttttga ctgtttcatc aggaatttct tgaaaaataa gtttgaaacc
    27901 ttggttaaaa agtcttttat ttcattatct ttcacatttt cgtaaaaatt tgattgattt
    27961 cctgtattta ttttatgata atcgtttgac agttttttct cttttttaac ataaagggct
    28021 tgcatttttt atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg
    28081 gaatggacaa ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa
    28141 catataaagg aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa
    28201 acaggacttc tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt
    28261 taccagaatt ttccttttgg tgcagcccac ggtttaaaat cttgggcaca gctagaaagt
    28321 gatgatttga ttcactttag agaaactgga gtcaaagttt tgccggatac tccattagat
    28381 agccacggtg cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat
    28441 acaggaaatg ttcgcgatga aaactggatc cgtcacccat accaaatcgg tgctttgatg
    28501 gacaaggagg gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct
    28561 actgaccact tccgcgatcc acaaattttt aactttaaag gtcaatacta tgctgtcgtc
    28621 ggtggacaga acttggagaa aaaaggcttc gtccgtctct acaaggctgt caataacgac
    28681 tacacaaact ggcaagcagt tggcgacctt gactttgcta acgaccgtac tgcctacatg
    28741 atggaatgtc ctaatctggt ctttgtagag gaacagcctg tccttctcta ctgtccacaa
    28801 ggattggata agaaagttct agactacgat aatatctttc caaatatgta taagattggg
    28861 gcttcctttg accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat
    28921 tacggtttcg aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca
    28981 gttagctggc ttggtttgcc agatgtttct tacccatctg actgttttga tcaccaagga
    29041 accttctctt tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc
    29101 gctgctatta aggaccttcg tgcttctgaa gaagccttct caaaccgttc ccaaaccaag
    29161 aacacttacg aacttgaact caacttggaa gctaatagcc agagcgagat tgtcttactt
    29221 gctgataaag aaggtaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca
    29281 gtggatcgta gccaggctgg agaacagtat gcccaagaat ttgggacaac tcgttcttgc
    29341 cctatcgaga atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt
    29401 ttcatcaata aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat
    29461 ggtatcctga tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc
    29521 aaaactaact gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat
    29581 caataaaaaa gggtatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgagaga
    29641 attgggctat aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat
    29701 cggcttgatt ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga
    29761 acaccaactc ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga
    29821 gaaggaacgc gaatacatcg aaatgttgga agccaatcag gtagacggca tcatttctgg
    29881 tagtcacaac ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga
    29941 ccgaaaccta tcgccagaca tccctgttgt ctcctctgac aactatgctg gtggggttct
    30001 tgctgcccaa accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga
    30061 caattccaat tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc
    30121 tcctattatc aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa
    30181 tatcttgacc cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct
    30241 ggtcattaaa atcgctcaag aattgggcat ttctgtccca aaagagctca aggtcatcgg
    30301 ctatgatggg acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc
    30361 tttggaagag attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga
    30421 agtcgccaca actggttact tcttaccagt tacgctatta ccaggaaaaa gtatttaaac
    30481 acaagaaaac tcagaccgat tcgtctgagt ttttatgatc ttaaattttc gagatagcgc
    30541 tgggctgtct ctaggttaaa ggttttatct gagatgaggc gctctactag gggagcaact
    30601 tcagattcac tagccccagc taggagagct agggatttgg cctgtagttt catgtggcct
    30661 tgctggatgc ccgtacttac caaggctttg agggctgcaa aattttgagc aagaccgatg
    30721 gacacgataa tctgggctaa ttctctggca gaaggatttc ctagtagatc atgactgaga
    30781 gctacacgtg ggttgaggcc gatagagcca cccttagtcg ctacaggcat gggcagggtc
    30841 atctcaccga ccaattcttc tctttcaagg tccagcgtcc agcagctaag accttgatag
    30901 cgtccatctc gactggcaaa ggcatgggcc ccagcttcga tggcacgcca gtcattacca
    30961 gtggcaatca aaatcgcatc aataccatta aaaattcctt tattatgagt agcagctcgg
    31021 taaggatcag cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat ctctcgtcct
    31081 tgatcctttt ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt caccagagaa
    31141 tcagtcgcgt agttggacag gattcccatg agactctgtc cctgactgag ttcttctaag
    31201 actggtttca aggcttccag catggtgttg agcatattgg cacccatggc ttcctgggta
    31261 tcgacatgaa tataaacaac gagaaagtct ggttcgcctt ttatctgctc gacatgcaga
    31321 tcacgcgccc cacctccacg tttaacgata gaaggatagg cttgattggc aagctccaag
    31381 agctccgctt tcttgctggc aatcttctct tgcgctagtt taggattagc aacttgataa
    31441 agggctacct gcccaatcat ctgtcgctga tggacttgtg cagtaaaacc acctgcacgc
    31501 ttgatgattt tgctggcata gctggccgcc gcaaccacag agggttcttc tgtcacgtag
    31561 ggaacggtgt attcctgacc gttgacaagt acctctggaa ccagtgaata aggcagagaa
    31621 aaagttccca ctacattctc actcagctgg tctgccacag tcacgctcat ctgttcatcc
    31681 ttctccagac tagcttgtct ctcaggacta aggagcgcct gagcttttaa cagctcgagg
    31741 cgctcttggt atgatttttt agaaaatcca ttccaactta tcttcattat ttttcaacct
    31801 tgctataacg gcgttggtgg tcgagaattt caaccaaggc aaaatcttga ttttcatagc
    31861 cagcaaactg ggcagagttt gtttcatcca agtttacttc ctcaaaaaag accttttcat
    31921 agtctgcaac ggatagggca gttcgttggt tgagcttgtt caaacggtct ttattcaaat
    31981 aagcttcata tccttcaacc aattcaccac tgaagaactc agccacagct ccacttccgt
    32041 aactataaag ggcgatttta tccccagctt tcaagctatc tgtattttcc aagagagaca
    32101 aaagtccaag gaaaagtgaa cctgtgtaga tattccccac cttttgactg tagagaatag
    32161 actggtcaaa atgcttttgt aagaggtctt ttttctcttg aggcaggctc ttatccatga
    32221 tttttttcaa gccttttagc gctaatttag gataaggcaa gtggaaacaa acagccgcaa
    32281 aatcatccaa agtaagctgg tagcgttttt gatattcaag ccaagtcgtt ttcaaactat
    32341 ccaagtattg ttgggtagaa tagacaccat ttacataagg agttgtcgag taatttggtc
    32401 gccagaaatc catgatgtca cgggtctgag ctacattgtc attattaaag gccatcatgc
    32461 gtggattttg tgtaatcaac atagctacac ttccagcacc ttgagttggt tctcccggag
    32521 tttcaatacc atatttggca atatcactgg caatgaccaa taccttggac tccggagaat
    32581 tttccacatg caatttggca taatggaggg cagctgtcgc cccatagcag gcttctttaa
    32641 tctcgaaact acgagcaaag ggctggatgc ccagcaagcc atgcacaaag acggccgcag
    32701 ccttactctg gtcaattcct gactcggtag ccacaatgac catgtcaact tcttgtcttt
    32761 cttgctcagt taaaatagag tcactagcac tggccgccaa ggtcacgatg tcctcagtta
    32821 ggggcgcaat actcaattcc ttgagtaaga gtcctttact taatttttca gggtcaattc
    32881 ccctcgcttc tgctaagtct tgtaatttca agacatattg actggtcgca aaaccaatct
    32941 tatcaatacc gattgtcata tttacctctg ttttatcatt catgtaaaaa atcgttctat
    33001 actattttat cacaaatggc agtaaaagag agaaaaaaga cttgattcac caaatcaagc
    33061 ctcttattgg tcatcatttt aaagaatgat tagttgctag agagttcacc gatataagta
    33121 gctttataag ctccattcac agttatcagc tcctggagga tcaaatttcc tgagtaaatc
    33181 cttcccatct catctacaaa tttttgataa aactgactgg tcggaatttc tctgacatcc
    33241 ttatcaaatg tcttgtcaag tgttttacta accttctcag caatcaattg atgctcttgc
    33301 catccacttt gaaactctga gcccgaacta gaaaccatga ctgggataaa caacaaggtc
    33361 agtagattta cagacaataa ggaaagtagt agacttcctg caaaactaga atcctagttc
    33421 atgattgata at
//
LOCUS       DBEJZJ010000019        31807 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000019 DBEJZJ010000000
VERSION     DBEJZJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.19"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..297)
                     /locus_tag="ACL3R8_001218"
     CDS             complement(1..297)
                     /locus_tag="ACL3R8_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314095.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL3R8_001219"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL3R8_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR1314096.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="ACL3R8_001220"
     CDS             complement(3571..4797)
                     /locus_tag="ACL3R8_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR1314097.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="ACL3R8_001221"
     CDS             complement(4840..5532)
                     /locus_tag="ACL3R8_001221"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR1314098.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="ACL3R8_001222"
     CDS             complement(5705..7456)
                     /locus_tag="ACL3R8_001222"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314099.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7446..9191)
                     /locus_tag="ACL3R8_001223"
     CDS             complement(7446..9191)
                     /locus_tag="ACL3R8_001223"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314100.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9319..9849)
                     /locus_tag="ACL3R8_001224"
     CDS             complement(9319..9849)
                     /locus_tag="ACL3R8_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR1314101.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(9846..10302)
                     /locus_tag="ACL3R8_001225"
                     /pseudo
     CDS             complement(9846..10302)
                     /locus_tag="ACL3R8_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10436..11263
                     /locus_tag="ACL3R8_001226"
     CDS             10436..11263
                     /locus_tag="ACL3R8_001226"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR1314102.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11275..11526
                     /locus_tag="ACL3R8_001227"
     CDS             11275..11526
                     /locus_tag="ACL3R8_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1314103.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            11533..11661
                     /locus_tag="ACL3R8_001228"
     CDS             11533..11661
                     /locus_tag="ACL3R8_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGR1314104.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      12044..12139
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12539..13120
                     /locus_tag="ACL3R8_001229"
     CDS             12539..13120
                     /locus_tag="ACL3R8_001229"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR1314105.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13120..14382
                     /locus_tag="ACL3R8_001230"
     CDS             13120..14382
                     /locus_tag="ACL3R8_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR1314106.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14469..15335)
                     /locus_tag="ACL3R8_001231"
     CDS             complement(14469..15335)
                     /locus_tag="ACL3R8_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HGR1314107.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15322..16092)
                     /locus_tag="ACL3R8_001232"
     CDS             complement(15322..16092)
                     /locus_tag="ACL3R8_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR1314108.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16118..16972)
                     /locus_tag="ACL3R8_001233"
     CDS             complement(16118..16972)
                     /locus_tag="ACL3R8_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HGR1314109.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17129..17533)
                     /locus_tag="ACL3R8_001234"
     CDS             complement(17129..17533)
                     /locus_tag="ACL3R8_001234"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR1314110.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEDRQVRI"
     gene            complement(17603..19084)
                     /locus_tag="ACL3R8_001235"
     CDS             complement(17603..19084)
                     /locus_tag="ACL3R8_001235"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR1314111.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19103..20281)
                     /locus_tag="ACL3R8_001236"
     CDS             complement(19103..20281)
                     /locus_tag="ACL3R8_001236"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR1314112.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20446..21453
                     /gene="galR"
                     /locus_tag="ACL3R8_001237"
     CDS             20446..21453
                     /gene="galR"
                     /locus_tag="ACL3R8_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR1314113.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21499..22536)
                     /locus_tag="ACL3R8_001238"
     CDS             complement(21499..22536)
                     /locus_tag="ACL3R8_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR1314114.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22537..22890)
                     /gene="nmlR"
                     /locus_tag="ACL3R8_001239"
     CDS             complement(22537..22890)
                     /gene="nmlR"
                     /locus_tag="ACL3R8_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR1314115.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23134..24024)
                     /gene="czcD"
                     /locus_tag="ACL3R8_001240"
     CDS             complement(23134..24024)
                     /gene="czcD"
                     /locus_tag="ACL3R8_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR1314116.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24157..24693
                     /gene="sczA"
                     /locus_tag="ACL3R8_001241"
     CDS             24157..24693
                     /gene="sczA"
                     /locus_tag="ACL3R8_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR1314117.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24860..25666)
                     /gene="pnuC"
                     /locus_tag="ACL3R8_001242"
     CDS             complement(24860..25666)
                     /gene="pnuC"
                     /locus_tag="ACL3R8_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR1314118.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26011..27531)
                     /locus_tag="ACL3R8_001243"
     CDS             complement(26011..27531)
                     /locus_tag="ACL3R8_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR1314119.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(27524..28252)
                     /locus_tag="ACL3R8_001244"
     CDS             complement(27524..28252)
                     /locus_tag="ACL3R8_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314120.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28267..29031)
                     /locus_tag="ACL3R8_001245"
     CDS             complement(28267..29031)
                     /locus_tag="ACL3R8_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR1314121.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29035..29478)
                     /locus_tag="ACL3R8_001246"
     CDS             complement(29035..29478)
                     /locus_tag="ACL3R8_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR1314122.1"
                     /translation="MRDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30160..30456)
                     /locus_tag="ACL3R8_001247"
     CDS             complement(30160..30456)
                     /locus_tag="ACL3R8_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR1314123.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLASFIKREESKYRGTATSALMYEELFKML"
     gene            complement(30478..31542)
                     /gene="pepA"
                     /locus_tag="ACL3R8_001248"
     CDS             complement(30478..31542)
                     /gene="pepA"
                     /locus_tag="ACL3R8_001248"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR1314124.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT         9460 a         7147 c         5647 g         9553 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccgt
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca ccgaatatac
      841 tattctctga cactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac tgtcccgatc
     2701 aatttgtcct attcttgttt cattttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttgttgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttacctgaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat atttgcgtta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgctagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct ataccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 acaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaacctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaacagca tggaatgaga aggaagtaaa atcagcgata gaaccagaag gttgtccttt
     4261 ataagtagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactgggata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc
     4741 agcaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgatga tggtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aattcctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tacggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacggaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 cttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagaag ttagaaccag
     5401 taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtataggcc atggcccctg cctgcaaact atacatcttg tgataggttc
     5761 ctcccagagt caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcgtct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaaact ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca ggagagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actgatttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgtaaaacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatac gagaaacaca
     6421 catgttcaaa acggatattg ccttctttga ctttggcttg cccattttct tgaaggggct
     6481 cataggtcct ctcatcgatt aaggcaaaga cacggcctgc agaaaccata gacgtttgca
     6541 gtgttgaaaa gttttgcgtc acctcaatca aagggtcaaa gaggcggttg atgtactgga
     6601 taaaagcata catggtcccg gccgttatcc cgatagaaag accacgatag ccaaaatagg
     6661 tcatcaagac agcataacct agaagtttca acaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcatagg ccaagtgctc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaaag cctgaataat cctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaggg gagaaagagc aagactaatg
     6961 ctgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gccgacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt cacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacaagggg aatgacactt ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtaaggag tccataaggc ttgagatagg acatcaagcg cttcaataca gtccattgtt
     7441 cttgtttatt ctgcatcttc ttctcccttc atttccagct gctgagactg gtaggtttgg
     7501 gcataccagc catccaaagc tagcaagtct tcgtgcctgc ctcgttcgat aatttgacca
     7561 ttttgcagga ctaaaatcaa atctgcatgg acaactgcac tcaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa aaagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatgg cgcccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactcc
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccaccaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gcataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga tgtgatggca
     9061 tcaataaccc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaattc cgactagata acggcgtttt tctaacttga aaaaccacca aagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agagattttc gaagagtaca agaccccagg tttttctttt tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca caacgataag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttctgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagccatt tgagagtcaa gaccagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaattcggt tcccttttta tcatggtatg ccttgaaagc
    10201 aaaaaaaact gtcacagcta atagaacaat cccaaagcca accatgatac cattttgctg
    10261 accgatttgg ctgagtacat agtcataaga gtagaatttc atatattttc actctctttc
    10321 ataaaatcat tcttaattat aaacgaaaga gagtaatttt tcaaaccata cgttggggaa
    10381 atagatcttt ttttggtata ataaaatcta taatctgaat gaaaaaggta actttatgaa
    10441 acttatctca tggaatattg attccctaaa cgctgcccta actagtgact cagctcgtgc
    10501 caaattgtcc caagaagtcc tacaaacctt ggtcgctgaa aatgctgata ttattgctat
    10561 ccaagaaacc aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga
    10621 actcttccca ggctacgaaa acacgtggcg ctcttcccaa gagcctgccc gtaaaggcta
    10681 tgctggaacc atgttccttt ataagaaaga acttacgcct acgatcagct tcccagaaat
    10741 cggtgcccct tctaccatgg acttggaagg ccgtatcatc actctagaat ttgatgcatt
    10801 tttcgtaacc caagtttaca ctccaaacgc tggtgacggt ctcaaacgct tggaagaacg
    10861 ccaagtctgg gatgttaaat atgctgagta tttggctgaa ctagacaaag aaaaaccagt
    10921 ccttgcgacc ggtgactaca acgtagccca caatgaaatc gaccttgcaa atcctgctag
    10981 caaccgccgt tcacctggat ttactgacga ggaacgtgct ggatttacca accttttggc
    11041 aactggattt acagacacct tccgccatgt tcatggcgat gttcctgaac gctacacttg
    11101 gtgggcacaa cgcagcaaaa cttctaaaat caacaataca ggctggagaa tcgactactg
    11161 gctcacaagt aaccgtatcg ctgacaaggt cactaaatct gatatgattg actcaggtgc
    11221 tcgccaagac catacaccga ttgtcttgga aattgacttg taaggatttt ctatatggac
    11281 tacaatgcgg tcattcccga gttgcttgta tcgaatatcg aacagtctcg gtccttctac
    11341 tgtggtttac tgggttttag gattgaatac caacgtccag aagaaaactt tctctttctt
    11401 tctcttgaag agtgtcaact aatgttagag gagggaacaa aggatcaact agctgaactg
    11461 acctacccct ttggtcgtgg agtcaatctc tcctttggca taaaggatgt ttcaaaactc
    11521 tattaaagag tgatgaaggc aaactatcct atttatcgtc ccttgaccaa aagaaagttt
    11581 cgtgtcagtg atccctatat ctatcctcat aaatttgcag ttttggatcc aaatggctat
    11641 tttttaagat ttagcgagta gaataataaa aattgggaaa agtctttaaa gttagaaaaa
    11701 ggcatattgt caggtgttta aaaacttgat agtatgcctt ttatgatgga aaaatcttct
    11761 aatactcttc gaaaatctct tcaagccaca tcaacgtcgc cttaccgtag gtatatgata
    11821 ctgactctgt caattctatc cacaacctca aaacagtgat ttgaggttgt ggatagcttc
    11881 ctagtttgct ctttgatttt catttagtat aaatgttagc ttacaatgca gtttttgttc
    11941 actccttctt ctgtttgttc gttttttaaa ccaaaatact aacaaaatag ttgatttata
    12001 aagttattta gtgtaaaata aaaacattgg ctcaaaccta tttaaaattg aatatcgttt
    12061 tacttgttta tgtcgtgaat tggcacgacg tttctacaag gtgccggaac acctaacaat
    12121 aagtaagtca gcagtgagat atggccgttt ttgccatgcc tatttggggg acttacttag
    12181 agattaagta ggtctttttt gaatattttt aatatttccc ttaattagtg cggacgggag
    12241 gtgaaattat cctgtgaata atttcaggaa tccagggaat ttcatcccta atttttgagc
    12301 ccctagctct ttcatttcta ggcttaggct aaaatagttc cccgaactat tttactctca
    12361 aaaatcccgt catagacaat aacaagatta ttgtctatga taccactaca acgggaaata
    12421 tttgataaga ctcgcttcgc tcgtaatagt tttatcaaat atatagtatt agcaaaaggg
    12481 atcactatag aaacatttaa acaacaagta aattaacttt tagactttag gaggtcttat
    12541 gaaattatta gaagagcgca tcctcaagga tgggcatatc ttgggtgata acatcctcaa
    12601 ggtagattcc tttttaaccc accaagttga ctttagcttg atgcgagaga ttggtaaggt
    12661 ttttgcggaa aaatttgctg ctgctggcat taccaaggtc gtaaccattg aagcgtcggg
    12721 tattgcccca gccgttttta cagctgaagc cttaaacgtt cccatgattt tcgccaaaaa
    12781 agctaagaac atcaccatga acgaaggcat cttaactgct caagtctact cctttaccaa
    12841 gcaggtgacc agcactgttt ctatcgctgg aaaattcctc tcaccagagg acaaggtttt
    12901 gattatcgac gatttccttg ctaatggcca agctgctaaa ggcttgattc aaatcatcga
    12961 acaggccggt gccacagtcc aagctatcgg tatcgtgatt gagaaatcct tccaagatgg
    13021 tcgtgatttg cttgaaaaag caggctaccc tgtcctatca cttgctcgct tggatcgttt
    13081 tgaaaatggt caggtcgtat ttaaggaggc agatctctaa tgcaaactca agaaaaacac
    13141 tcgcaagcag ccgttctggg cttgcagcac ttactagcca tgtactcagg atctatcctg
    13201 gttcccatca tgattgcgac agcccttggc tattcagctg agcagttgac ctacctgatt
    13261 tctacagata tcttcatgtg tggggtggca accttcctcc aactccaact caacaaatac
    13321 tttgggattg gactcccagt cgttcttgga gttgcattcc agtcggtcgc tcccttgatt
    13381 atgattgggc aaagccatgg tagtggcgct atgtttggtg cccttatcgc atctgggatt
    13441 tacgtggttc ttgtttcagg catcttctca aaagtagcca atctcttccc atctatcgta
    13501 acaggatctg ttattaccac gattggttta accttgatcc ctgtcgctat tggaaatatg
    13561 ggaaataacg ttccagagcc aactggtcaa agtctcttgc ttgcagctat tactgttctg
    13621 attatcctct tgatcaacat ctttaccaaa ggatttatca agtctatctc tattttgatt
    13681 ggtctggttg ttggaactgc cattgctgct actatgggct tggtggactt ctctcctgtt
    13741 gcggtagctc cacttgtcca tgtcccaact ccactctact ttgggatgcc aacctttgaa
    13801 atctcatcta ttgccatgat gtgtatcatc gcaacggtgt ctatggttga gtcaactggt
    13861 gtttatctag ccttgtctga tatcacaaaa gatccaatcg acagcacgcg ccttcgcaac
    13921 ggttaccgcg cagaaggttt ggcggtactt ctcggaggaa tctttaacac cttcccttac
    13981 accggatttt cacaaaacgt tggtttggtt aaattgtcag gcatcaaaaa acgcctgcca
    14041 atctactacg cagctggttt cctggttctc cttggactgc ttcctaagtt tggtgccctt
    14101 gcccaaatca ttccaagctc cgtcctcggc ggtgccatgc tggtgatgtt tggttttgta
    14161 tctattcaag ggatgcaaat cctcgcccga gttgactttg ctaacaatga acacaacttc
    14221 cttatcgcag ctgtttcaat cgctgcaggt gtcggtctca acaacagtaa tctctttgtc
    14281 agcatgccga cagccttcca aatgttcttc tcaaacggaa tcgtcgtagc cagcctactc
    14341 gccattgtcc tcaatgccgt attaaatcat aaaaagaaat aagaaaaaga ggtgcgagcc
    14401 tcttttttgt ttatcacaaa ttgattataa atacaatcaa tcccaattcc catctaattg
    14461 aattggacct atttcaaatt ctttaaaata ttatgttcca aatcgttaat attatataag
    14521 aatggtaaaa tatcaaatgt ttctcgtaaa ttattcttag ccttatacca accttgtcca
    14581 tcagtaatcc acataaactc aacattagga atagctttag tttcttcagc aatcattttg
    14641 taagatctag ccgtctcatt taattttgaa ccacttcctg aataaaaatt aacctcaatc
    14701 agataaagca cttgttcatt ttttatgaca aaatcaaaac gtttcacagt attcccatca
    14761 ttcgtaatag cagataaatc gacagaaaaa atttcctcta tttcattttg ttcaatctct
    14821 ttaaataaat tctctcctaa aatataccct tcagcttcaa gatagctttg aacaatattt
    14881 tccatcgcat ctccagtccg atttttgcgc ccattagtat ccataccaac ctcaacacct
    14941 gtaacgtagt caactaaatt tgatactaaa tgattttgca ataaatcaaa tatacctgat
    15001 ttttccaaaa acatagtata ttcttcaata ctatagtttc gtttactaaa atcaaaatag
    15061 aaatctttta tcggatcctt aacaataatc gtatctctca aacgtttagc aataagtaga
    15121 ggcacaactt tcaaaatttc tggataattt tgatataagt ctaaaaaatc ctcttgtata
    15181 tttttactac caataagact attcataata tttagagcaa cttttatact agatacattt
    15241 ttataaacct taggaaaatc tgtataataa gtccagtcag ctactgtgtc ggtcatcgtt
    15301 gacaaccact catcaaaatt tctagtttgt ttcattttct gcctccaacc tcttccttgc
    15361 aatttttaaa tattcttttt cagcatcgat acctataaat cttctaccta accgcttcgc
    15421 aacaacaccc gtagtgccac taccaacaaa tgggtctaga atatagtcac cctctttagt
    15481 agaggctaaa ataatacgtt ctaacaaata ctctggtttt tgagttggat gtttcccagc
    15541 ccatttttca actttctttg ttaaagaacc ggtccagaca tctttcattt gttttccatc
    15601 attcaattct ttcattaaat cataattgta gtaatgacga gcttttttat cattttttct
    15661 ggcccataaa atggtttcag tagaatgggt aaaataacga caagataaat tgggggcagg
    15721 gtttgttttc tgccaagtaa tattattcag aattttaaaa ccttcttgtt ctaatgccat
    15781 tccaactgag tatatgttgt gcaaactacc tgaaatccat accgtcccat taggcttcag
    15841 aacttctttt gctaggcgaa tccatttacg attaaactca tgtttttctt cgaatgaaga
    15901 aattttatcc caatctcctt tatcaacaga aactacttgt cccccagaat tagatattcc
    15961 accattactt aaaaaataag gtggatcagc aaaaatcata tccatacttt ctggtttcat
    16021 ttttgataag aacttgaacg tatctgaatg aacaagaatc atcttatttt tattgtagta
    16081 tggttttgtc ataagaacac ctccatactt atattcgtta tttttcataa tttgtgacta
    16141 taatttcaga aatttttcct cgacttgaag attttgctcc attagttcgg gtagcttcaa
    16201 cataatgtat attaaaatcc ttatacaact cctctactaa agcactagaa gaatttgata
    16261 acataacata agctcctgta tcactcaatc tcttaaaggc atctcttaat cttacttgat
    16321 ctgcaaaaga gaatccctca tgagtataag acgtaaatgc actcgtctca gacaatggaa
    16381 tatatggagg gtcaaaatac acaaaatctc ctgttcgaac atctacaatt gccttttcaa
    16441 aatctcccac tttaatttct agttgattgt tatttatata aactgaaata gcagatatca
    16501 attcctcatc aacaatttta ggattcttat aacgtccata tggaacatta aattgattct
    16561 tagaattcac acgatataga ccattaaagt tcactctcaa catatataga atacgtgcag
    16621 ctctttgtac ttcggacatc atatctattc tttcatcacg atctgcagaa cgtaaatcta
    16681 aataatattc ttttgaatta tattcctgat gaactttcaa aatttcaatc aattcttgag
    16741 gattgtcctt aatttgttga tagcaattta ttagttcagc gttaaaatca ttaataactg
    16801 catctttagg agccaaatca aaaaataaag ctccacctcc aacaaaaggt tcgaaatacc
    16861 tgttataggt tttaggtatt aattctctaa taacaggcaa taattgtctt ttaccacctg
    16921 tccatttcgt gaacggttgt aaagtaactt tctttatttc ttttatcttc atgcttttaa
    16981 ttataccata gaaattaaaa cacaactctt gtattttcta ccacattact aaattttcta
    17041 ttttagaatt aaatcatatc aatatcaaaa aatgagtaag gcaaatctta taaattccaa
    17101 aattcacctc actctattaa attactcttt atatccttac ctgtctgtct tctgaccgct
    17161 ggcctgtgac aaacatggta aaggttgctt tgcagacatt tctgccttct tgattggtga
    17221 tatccacatc cattacacag gttgtacgac cttgatggac acattctcct ttaatggtca
    17281 atacatcgtc gagttttcct gccttaaggt agttgataga ggattggagt gtcaccccat
    17341 caagtcccag cgagataacc accaaaccac tgatttggtc acatagcgtg aatagatagc
    17401 caccatgggc attgccatag tagttgagcg acgagttcac tactttggtc gtcaccacaa
    17461 cgtgaccatc tctcattttt tcaatttcgt aattttcaaa ggcagatata gcgtcaaaat
    17521 gaaagtcttt catcgtttcc tcctgatatt tcaaacgaca ctatgatact actttttata
    17581 ggactgtgca aggagaaagc tcctagtcta gtaaaattcc gacctgttcc acaaagcgca
    17641 taaaggctgt ctgaccttgt tctgtctgct tgtagactcc tgcatcctca agtacacgca
    17701 caaagatagc acccacagag tccttgacga ttgcaagggc tttttcttta tccgttaggt
    17761 ctggatgttg ggatttgagt tggtctgccc actcctgatg ataatcggca actgtaacag
    17821 cttctcctac aagatagcta gcgacttgct ccacttcttc tttcagacgt ggtggcaaga
    17881 ttgccaagcc catgacctca atcaagccga tattttcctt cttgatatgt tggacatcct
    17941 tgtggggatg atagatgcca tcaggatgct ctgctgaagt ctgattgtct cgcaagacca
    18001 agtccaactc aaactgtcca tcacgcttac gcgctattgg tgtgatggtg tgatgcggtg
    18061 tcccgtctgt ctctgctaaa atctgcacac tagaatctga atactgacgc cattcctgga
    18121 aaatcttatc agctaagtta atcaaatcct ctttggaatc cgaagtcaag cgtaggacag
    18181 acattggcca cttgataatt ccagccttga cctgctcaaa accagcaaat cggaaggtct
    18241 tttgcaaggg agccaattcc ataggaaata cgtgacggcc tccctgataa tgatcatgag
    18301 ttagaataga gccccccaca atcggcaggt cggcattaga tccagcaaaa tatcctggaa
    18361 actgctctac gatagccaac agacgttcaa aactctgacg actaatggcc atgggacgat
    18421 gctggccatc taaaaagata caatgctcat taaagtaagc atagggcgaa tactggaacc
    18481 cccattcctg accaaccatt tcaaaacgga taatccggtg gttgctgcga gctgggtggt
    18541 tgacccgacc atggtaaccc tcattctcta aacaaagttg acactgagga taattactag
    18601 cttgcaccaa cttggctacc gcaatctctt tcggatcctt ttcaggctta gagagattga
    18661 tggtaatttc aagttctcca taatcagatg gaacacgata agcgatattt ttagcaatgg
    18721 ccttgagttt gatgtagtca tttttccgac tgagttgata aaaatcctct atcgcttgct
    18781 caggagagta ggcataggct tcccagaagt cacgattgac ctgactcgga caaggagtca
    18841 ccaagtccat cagttcagta ccaaggattt cacgcgcagt ctgactatcc tcaatcatct
    18901 ctaatcgaac ggcttcctca actagctggt ccttgaggtc aatcaattta tccagattgg
    18961 tctcaacttc caaaacacct tctcccactc gtgccaaaac acgattggtc aggtagattc
    19021 gatccatttc ctcaaatgaa ctttcagaaa tgacatgtgt tacaaattta tctactaagg
    19081 tcactataga gcctcctttt gactagtcaa ggacgcgagt cccacctgca acttcagcga
    19141 tatagaagct tggagcgtat ccaactactt cctcgtagtg tttgcctaca gcttccttaa
    19201 aggcctcaac agtatctttt tgaaccaagg caatggcaca gccaccaaaa ccagcccctg
    19261 tcatacgagc accgagaact ccttcttgtg cccaagctgt gtgaacaaga gtatccaatt
    19321 ccaaaccagt tacttcataa tcatgctcca gagaaacgtg tgacgcattc atcaaacgac
    19381 caaatgtttc caaatcacct gcttgaaggg ctgcttgagc tttaagggta cgttggtttt
    19441 caagcacagc atggcgagca cgtttcaaac gattttcatc tttaatcaaa tagctatatt
    19501 ggtcaacggc ccactcgtcc aattcaccca gggtctgaat atccaaggca acttgcaatt
    19561 cttccactgc tttttcacac tcagcacgac gttcattgta tttagagtcc gccaattcac
    19621 ggcgtttgtt ggtgttcatg ataacaacga cattgtcctt caaatcaagt ggcaccaaat
    19681 catactctaa ggtgttggta tcaaggtaaa tagcacgttg atcagccccc ataccaatag
    19741 caaactggtc catgatacca gagttgactc cgataaagtt attttctgtt tgttttccga
    19801 ttttaaccaa atcgagacgc tctaatttta aatcaaagag atgctctgcc actacccctg
    19861 tcaagagctc caaggatgct gaagaagaca aaccagcacc atttgggata ttcccataaa
    19921 cataaaaatc aaaacctttg tcaatcacgt gcccagcttc ttgcaagaaa tgaaggacac
    19981 cttttggata attggtccag ttgtgctctt tttcaaactt gaggtcagcg agaggcactt
    20041 cgataatgcc cttgtcctca aagttagctg agtagaaacg caagacttgg tcatcacgct
    20101 tacgagctgc accgtaagtt cccaaggaaa tagcagcagg aaaaacgtgc ccaccgttgt
    20161 agtctgtgtg ttcaccaatc aaattaatac ggcctggtga aaagaaggtt tggtctgctt
    20221 cttgaccaaa aacagcaaga aagtctttgc gaaggacttc agtagtaaga tgttgtgcca
    20281 tatgaattct cctttgactg tccgttaagc catcttaacg tgtaatcgtt ttctttctat
    20341 tgtatccaag gaatttccca aggtcaatcc tttttactaa aattttacta aaatatcagt
    20401 aaaaagaaga aaaatatgat atactaacct aatcaaggag gatttatggc taccttaaaa
    20461 gacattgcac agctagcctc tgtctcaatc gcgaccgtat cccgtgtcct caaccgcgac
    20521 cagagcctat ctgttacaga agaaaccaga caccgtattt taaccgttgc tgaagagcta
    20581 ggctacacca aacatctcaa gacaggcgag tcccacaagc ccaagcaaaa gattgccatt
    20641 atccaatggg tcagcgaaca aggggagcta gacgacctct actactacca gattcgccta
    20701 ggaatagaaa aaagagccca agagttggac tacgatatct tgcgctattt taatgaccat
    20761 ccttttacct taagcgagga agtgattggg attctctgca tcggaaaatt tagccgagct
    20821 cagatttctg cctttgaaga ataccaaaag cctcttgtat ttctagacag cgatacactt
    20881 tccctgggac atacctgtat tatcacggat ttttacactg ctatgaaaca ggttgtcgat
    20941 tatttcctca gtcaagggat ggaccgcatc gggattctaa cagggcttga ggaaacaaca
    21001 gaccaagaag aaatcattca ggacaagcgt ctagaaaact tcaaaaacta cagtcaagcg
    21061 aggggaatct atcatgatga actggtcttt caaggaagat ttactgccca gtctggctat
    21121 gacttaatga aggaggccat tcagagcttg ggagaccaac ttccgccagc atttttcgca
    21181 gccagcgata gtttagctat cggtgccctc cgtgccctcc aagaagctgg aatcagcctg
    21241 ccagatcgcg tcagcctcat ttcattcaac gacaccagtc tgaccaaaca ggtctatcct
    21301 cccctctcta gtattacagt ttatactgaa gaaatggggc gagcaggtat ggatattctt
    21361 aacaaggaag tcctccacgg tcgcaaaatt cctagcctga ccatgctggg aaccagactg
    21421 acattaagag aaagtaccct aaatcaagaa taggataaca taaaaaacga atagagttct
    21481 aaaactccta ttcgtttttt attcgattac aatcatagac ttaattgtct tacgttcatc
    21541 catatctttg taggcttggt cgatatcttc cagtttataa cttgaagtaa agacgcgacc
    21601 tggattgata tcaccatcaa ggacggcttt tagtaaaaat tgcttatcgt atgttgtagc
    21661 agaagctgcc ccacctgcta cagagatatt ttgcataaat gtcgaaccaa gagcacgatt
    21721 attatagtgt gggactccta caaagcccat acgccctcca ttatgaagaa cacctagcgc
    21781 ctgttctata gcagcctccg taccaacaca ttcaagtgct gcgtctgctc ctccaccgag
    21841 gatttcacgc accttggtaa ttccttcttg accacgttct gcaacaacag ctgtcgcacc
    21901 tgactccata gccatctttt gacggtcttc atgacggctc ataaggataa tttgtgatgc
    21961 tccacgcatc ttagccgcga tgacagcaca ttgaccaaca gccccatcac cgataacaac
    22021 aaccttgtcc cctttttgaa catttgcaac acgcgccgca tgatagcctg tcggcatgac
    22081 atctgcaaga gtcaaaaggg actggagcat cccttctgta tagtcagaag gttgaccagg
    22141 gattttaacc agcgcccagt ttgcatagtg gaagcgaata tattctgcct gaaaatcacc
    22201 ccccaaatta ttgccaatat gattgtcgca agaaccgtca aatccagcaa gacaggcatc
    22261 acactcacca catccatgtg taaaagggac aatcacaaaa tcacctggtt tcaccgtcgt
    22321 aatggcttcc acagcttctt caacaatccc aatcgcttcg tgtccactat ttttgtgtcc
    22381 agctttcgtt tctggattac ggtacctcca taaatctgaa ccacaaacgc acgcacgaac
    22441 cacacgaata atcacatcat ccgcttctat tatttgcgga cgttcaatgc tagcaagtcc
    22501 aacctgacct gcctttgtat atactgctga tttcatttaa aattttcctt ccttataaag
    22561 tttaattttg agatttaaac gatttaaagc tgtctgtagc tgagacaagc gctcctctaa
    22621 tttttgcttt tcctcttcta aaataccaag cctctcctct ctcgtttcat ctcccttttg
    22681 gtagagcgac atatagtcaa ctaaactatc tacagagaca cccgccgaac gaaaacactt
    22741 aataaattcc agcgcttcga tatcctgatc ttgaaaatca cgaatcccag tagcagtacg
    22801 agtaatcggt ggcacaagac caacccgttc ataataccga atcgtatccg ctgaaattcc
    22861 caacaaatca ctggcagatt taatattcac acgctaacct cctctcattt cattcactga
    22921 attcacgcta ttctaactca cttatcttat tatataactt tgagttgact ccaagtcaag
    22981 cattttgtat ctaatcgaaa aatttttatc attaacaatc atatatctgg agtttataca
    23041 atgctcttct cttaccaatt tttgaaatat ttaaataata aagaaattac tctattccaa
    23101 ataagatagt acccaagtat ttttcacttt tttctaatgt tgatgctcat aactccgttc
    23161 caagtcacac acctttcgct tatgggtttg gtgagtttct aggtcagcat caatttcaat
    23221 ggtaatattt tgaaaaccac aatcttttag gaaaattcga atagactctt tacaagtttc
    23281 catatgttcc atttctttta gacaaacatg gacaatggca tttttttcca aagcatccat
    23341 agtccagaga ttaagctgat taaggctggc cacattgtcc aatcgctcca ggccactctt
    23401 tacttgcttg atatcaagac cttctggcac agcatccaag aaaatcttga gtgtagacca
    23461 aaaacgtgga agggcttttg aaagaataaa gaaagaaatg acaagggaca aaagaggatc
    23521 taggatatac cagtccgtaa atcgaagaac aatcgccatc aggataacag ctacccaccc
    23581 tagcgtatct tccagaaaat gcagactcag aatagactca ttctttgtct ttcccttacc
    23641 aaccaccaga ctcgctaaca gattgatagt aatcgcaata attcctaacc agagaatccc
    23701 ctcatcattg actggttgcg gatgcaaaat cttcgtgaca ttttccaaaa tgactagaac
    23761 agagcccgtt acgagaatca cagctgttac caaggctcct agcaggctaa accgcttata
    23821 gcccaaggtg tactgattgt cttcttcacg attggagatt gtttctagaa aagctgatat
    23881 tccaattgca atcgcatctc ccaagtcatg cacagagtca gcaagaacag cgctagaacc
    23941 aaatactcca cctgcaataa actcaacaat ggcataagtc aaatttaaga aaaaagccac
    24001 ccaaacagca tattttgcct tcatatttct cattcctttg ttataataga tttatgaaca
    24061 ccttgttcat tatcattatc cactaaaact caaagaaagg atagaagcaa aacgtcagct
    24121 ttattcagtt ctgaacaatt tgccttaagt gtccatatga ctaacattga ccgccgtatc
    24181 agcaaaacca aaaaagccat ctatcaagct tttatacaac ttttgaatgc taagggctac
    24241 gaggccacta ctgttcagga tatcattgat ctcgcagatg tgggacgatc caccttttac
    24301 tgtcactatg agagtaagga gcttcttctg gaccagctct gccgctacct cttccatcat
    24361 ctttttgaaa gagagcaagc catttcaacc gaggactacc tcgcccacct ctttctccat
    24421 tttcataaaa accaagacca tatcaccagt ctgctatttt ccaaaaatga ctacttcctc
    24481 cgtcaactcc ataaagagct agaacaccat gtctattccg tgctagctga taatttaaaa
    24541 gaagcccacc ctaatctgcc tacttcttac ctccaacact tggtcatgtc caactttatc
    24601 gagacattga cctggtggct caaaaaaggt caagatttca cagaccagga agttgtccaa
    24661 ttttatctag accttctcat tcctaaaaat tgaatataga gtaaagcttc agttgtctta
    24721 tttctaggtt actgagtttt ttatcttttc aacaacaaaa gaggacccgc cgatcctctt
    24781 tttcatacta taaatccttg attatcaact atatctgttt taatcgaaat ctcaaaacag
    24841 cactttcaaa catcttttcc tagttaagta aatcagtatt ctgcttagct gccttgctcc
    24901 attgatacca accaactaga ctgttaatga gataaattag atatttccct tgaatttgca
    24961 ggctttctcc ccaccagaga tagattgaaa agacattggt agccgcccag aatatccact
    25021 gttcacggta aacagctgtc atgaggattt gccctacccc attggttgca tctgtgattg
    25081 aatcacgata gggacgattg gcaccaatag actgataaat gaagccaaag gccaaccacc
    25141 aaagcacact aatggaaaga tactttgtcc agcccttgcc gtccagttta cgcgcgacaa
    25201 actcctgctt ttccttctta aactgtgcct gataaatcca aactagaagt ccaattggct
    25261 gcatgactgt gaagtaaagt gtcgtcagca cctcaccata aaagcctttc tgtagggcca
    25321 aaataaggta aataacagag ttaatcaagc caaaaagata attacttgct cgaccttccg
    25381 atacaaagat tacacagata atccctgtca agctacaaat catcccaatc cagtcaacaa
    25441 tacgatgttc gtaaaccaac tccagccaga gaggaaaact tcctaaaacc agcaaataaa
    25501 tccactgggc aaaactacga tgggcaaaga ggtcatccca gatagccttc atagttcctg
    25561 aaaatcctaa atcagccata gccgcaacca tacgacggta accacctgac atttcaccta
    25621 gggttgtttt gatattttca attttctttt gcaaataagt atgcatcatt tctccttttg
    25681 tttttaaaga gccgtgtctg gatagacttt cggacgcaac gctctattag ataatgaact
    25741 gcctatacac aagatttcta accttagtcg acatgagctg aaacctctta tttgttaagt
    25801 agttcacaaa atattataca cctattttat gaatagtcaa ctgtctttac agtaaaattt
    25861 tagaaaatca tgaaaatttt ctctttcttt ccattttaag tgacattcag tcattctcac
    25921 atcaaaaaag cccagacgaa attgtctgag cattctttta tctagtcgtt taaggaagtt
    25981 gagttcagta tgtttaaagt ctctgtccca tcatttcttc aacaaacctt gttcttggag
    26041 aaactccttg gctacttgct ttgctgactt gccttcaaca ccgacttggt agttgagctg
    26101 gctcatctgg ctttctgtaa tcttaccagc caatgtatta agaactcttt ccaactctgg
    26161 gtgtttcttg agaagagctt ctttcatgag tggagcccct tgataaggtg ggaagagttg
    26221 cttgtcatct tccaagacct gtaaatcata acgctccaat tccgcatcag tcgaataggc
    26281 atccgtgatt tgaatatccc ctgactgaat agcctgatag cgaagggctg gctccatggt
    26341 cgctacattg agattgagac catacattga ttgcaagccc ttatttccat cttcacggtc
    26401 gttaaactcg agtgtaaaac ctgccttcaa ctgcccttcc acttttttca agtctgaaat
    26461 ggtcttcaag ccatattctt gagcaatctt tttcggaaca gctacagcat aggtgttttg
    26521 ataagacatg ggtttgagat aggctagatg atcctgctta gcaatgccat cacgcgccac
    26581 ctgataaacc tgttctggtt catgactcac cttgggtgat ggttgaagca aactttcagt
    26641 caccgtacca gtaaattcag gatagatgtc aatatcgcct tttttcagag cttcataaag
    26701 gaagcttgtc ttcccaaaat tcggtttaac agtcgcagtc atgctggtat tttcttcaat
    26761 cagcaactta tacatattgg ccaaaatttc tggttctgga cctattttcc cagcaataac
    26821 caagttttcc ttctcttttt gaaccaaaag agctggacta taagacagac ccagtaataa
    26881 agccaccaag gcaaaacctg agaaaatcgt ccgtaatttt gctttttcca tcacttttag
    26941 taggaagtta aaggcaatgg ctagcactgc agaagaaagt gccccaatca aaatcaaact
    27001 ggcattatta cggtcaattc ccaaaagaat aaaggaacct agtccccctg caccaatcaa
    27061 ggccgccaag gttgccgtac cgataatcaa aacagctgcc gtccgaatcc cagacatgat
    27121 aacaggcatg gcgagtggaa tttcaaattt cttgagacgt tcccatctgg tcatcccaaa
    27181 ggcaatccca gcctcttgca ggttcggatc aattcccttc agcccagtga tagtattttg
    27241 caaaataggg aaaatcgcat aaatcactag agctgtcaaa gccggcaagg tcccaattcc
    27301 catcaaaggg ataaagagcc ccaacaaggc cagagacggg atggtctgga aaatacctgc
    27361 aatctgcaag acccagtcgg ccagcttctc atgatagcga agaaaaacag ccaagggaat
    27421 cgcaagcaaa atagctagta acaaggtcaa aagcgacaac tgcaaatgtt gagatagagc
    27481 tgtcaaccaa tcactaaaac gatcctgaaa agttgcaatt aaattagtca tgaacactac
    27541 ctccaaacaa gtctgctaca aagtctgttg caggcgcttt taaaattgtc tcgggattcg
    27601 ctacctggcg aatttctcca tcctgcaaga cagcaatacg gtccgccaac ttcaaggctt
    27661 catccgtatc atgggttaca aaaatcgttg tcatcccaaa ctctttatgc aattcttttg
    27721 tcagaacctg caactgtttt ctcgaaatag catccaaggc cgaaaagggt tcatccatga
    27781 ggaaaatctt gggctgacca atcatagctc ggacaatacc gacccgttgc tgttctccac
    27841 cagataattc actaggtaag cgatgcccat actcggctac tggtaaacca accttagcca
    27901 aaagctcttc tgttttcttc gtaatttctt ccttgctcca ccccttcatt tcaggaatga
    27961 gagcaatatt ttccgcaact gttagatttg gaaaaagagc aatagcctgt aaaacataac
    28021 cagtagaaag acgaagttca cgctcatcat agtctttgat gcgcttccca tccatataaa
    28081 tatttccatc agttggttcc aaaagacggt taatcatctt gagcatggtc gtcttacctg
    28141 acccagaagg ccctactaaa accataaatt ccccatcctc aatctgtaag ttgacatctc
    28201 tcaagacatc cttttctgtg tagcgcagtg ctacattttt gtattcaatc attctttgtc
    28261 ctcaatttaa aacttccctc gattggtcaa gtcttctacc ttaggcataa cttccttatt
    28321 atcccaatgc tccacaattt tcccgttctc taaacggaag atatcgtact gggcataagc
    28381 aacgccatca atctgagtct gaccatagct aaccacatag tttccttgtc ctaagagttg
    28441 gaaaacaaag tcaaaagtga cactatattc agccacatag tttttataag cagcacttcc
    28501 ttgtccaata tcatgattat gctgaatcaa atcgtctgcc acataatcac tccactgctc
    28561 tagctcccca ttttggaaaa tttctgtcaa gaaacggcga accagctttt tattttctgc
    28621 tttcttgtcc aaatccttga tttcaaaatc tccaaaaatt tgatctagtt ggtcattttc
    28681 aggtgttcga tagtagtcaa cgacatccca atgctcaaca atacgaccat tctcatccgc
    28741 acggaaagta tccgtcgtca cccattgagc ttctccacca ttcagatatt gatgaacatg
    28801 aacaaagacc agattgccat cctcaatggt gcggacaatc ttaatctgac gctctggatg
    28861 acgctcaaag aaatctgcaa agaaggctgc aaatccttct ttcccgtcag gaacacctgt
    28921 cgaatgttgg atataggtat cccctacaga ctgggcttga gcctcagcaa ctcgtccgtc
    28981 ttgaatggca tggatgtata ggttgtgagc atttttcact tgttgtgaca tattctaaac
    29041 ctcatttccc ttctctttca gattcgccaa aattctttct tgaaaacctt caaattggtg
    29101 aatttcttcc tctgaaaatc ctttgtaaaa gatagtatcc aatttctgac tgacacgatg
    29161 ccccacttct ttctgggact tgcctaactc cgttaaaact aaatacttct tacgcttgtc
    29221 ttttccacac ggactaacaa ttacaagctt ttgttcctct agctttttta tcatagtcgt
    29281 cagcgtatta ttcgcaagcc cagtcgcaag cgcgatatct gtcgcagttg cgcagccagt
    29341 ttcactattc cataaaaccg ctaaaatctt gccctgttca cccctataaa gagcctcagg
    29401 atcttgactc agtaactttt gaaaaatccg cccattcaac aaacgaatat gatgggctag
    29461 caaatgacta tctctcataa cacctccaat ttatttcgat atcgaaatga ataaaacaat
    29521 tgtaacactc atcgttctat ctgtcaacta tttcgatttg gaaataattt ttgataatta
    29581 tccacaccac catactccgg ctcaactaac ttttaacgag agtttctaaa ttccttcgtc
    29641 ctccagtcta caaaagcctt ccatccgtac tatcctatat tttatgaggg gacacatttt
    29701 tcctatcaga gcatttattt taaagataga agtaaatcat aattgcttcc atctgttctt
    29761 ttatagtata ttgaagttga actagggcac tgtatcttct aaaacattga taaaaagcga
    29821 tttgaatttc ccaatcaatt tgttcgtatt tatagcattt tgcaactgga ataggacacc
    29881 atgactgcta aaagatttct ataaattcat ttaatttcct caatcaattt gttcatatct
    29941 tatttcatcc cgttataatt tcaccttacc ctatcttttt cgtagcaccc ttcaaacagc
    30001 ctatccccta ccgtttgacg attcctcact tcgctccact tccattacag aagtttcttc
    30061 actactatgg tctcggctga cttctcatga ttccttgtta ctactatttg aacgctcacg
    30121 agataggtct tataaaaaat gctttgatcc acaatggaat caaagcattt taaagagttc
    30181 ctcatacata agcgcagaag tcgcagttcc tctgtacttg gattcttctc ttttgataaa
    30241 gctagccaag ttgagcaact caggtgctgg atgtttggga tttaggagca attcacgatt
    30301 gaccaggcct gagagacgaa ctgcctgcaa ttgctcattt gtagtaggca gttttttagt
    30361 agtctctagg agagcagcaa ctaaatcttc actcaaatca tgtcgagcat gattgtaaag
    30421 atcttttata aggctttcta ggtttggttc taccatccct accacctccc ttatggttta
    30481 ataatgttta atcaaatcaa ccgttgaacg atccaatttc ttcaccaagg cttgtaagaa
    30541 agcttgcgct tctaggaagt catccattgc atagagggtt tggtgagaat ggatataacg
    30601 agcgcagaca ccgatagttg ttgatgggac accaccattt ttcagatgag ctgcacctgc
    30661 atctgttccg cctttaccac agtagtattg gtacttgata ccagcttctt cagccgttgt
    30721 caaaaggaaa tccttcatcc ctggaagaag caagtgacct ggatcataga aacgaatcaa
    30781 ggttccatct ccaatcttgc cttgaccacc gtagacatca cctgctggtg agcaatcaac
    30841 tgcgaggaag acttctgggt caaacttggt tgtagaggta tgagcgccac gcagaccaac
    30901 ttcttcttgg acgttagaac ccagatagag ttcattgccg agtttttgac ctgataaagc
    30961 ttcagctagc tcgcttacca tgaggacacc gtagcggtta tcccaagctt ttgagatgat
    31021 atttttttca ttggctgtca aaattgcaga actatctggt acaatggtat caccaggacg
    31081 gatgccaaaa ctttctgcct cagccttgtc cgcaaaacca ccatcaaaaa cgatatcggc
    31141 aatggctggc atggttggtc ccccctttcc acgagtcaaa tgcggaggaa cagaacctga
    31201 aatcacagga atttcatgac catcacgagt caagagtttg aaacgttggc tgctaactac
    31261 catggggttc cagccaccga tttctacgac acggaaggta ccatctggct tgatttcgct
    31321 gaccataaaa ccaacttcgt ccatatgaga agcgaccaag acgcgcggtg catccacagc
    31381 ttctgaatgt ttgataccaa aaataccacc caagccatct gtcaccactt catccacatg
    31441 cggtgtcaac ttttcacgaa gataagcacg gacaggcgct tcatgacctg agactgcagc
    31501 aagttctgtt acttctttaa tttttgaaaa taatgttgtc atttcagttc cttctttctt
    31561 tcatccattt taccactttt tataggagaa ggatagtggg aaggtggatt tctaagttag
    31621 tatcttagtc ctgctctatc ttaaaaaagg atagtattct cttgcatgta gtgcaaaatc
    31681 tagtaaacat tccaaaatta actcgaatat ttatttccaa acaaaaaaca atacaccatc
    31741 aaagttgttt agatttttca tgaaatttac agaaaatagt tgacttccct ttcttctttc
    31801 tttaaat
//
LOCUS       DBEJZJ010000020        31208 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000020 DBEJZJ010000000
VERSION     DBEJZJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.20"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..467
                     /locus_tag="ACL3R8_001249"
                     /pseudo
     CDS             1..467
                     /locus_tag="ACL3R8_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            551..1258
                     /locus_tag="ACL3R8_001250"
     CDS             551..1258
                     /locus_tag="ACL3R8_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1314125.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1259..2590
                     /gene="pnpS"
                     /locus_tag="ACL3R8_001251"
     CDS             1259..2590
                     /gene="pnpS"
                     /locus_tag="ACL3R8_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR1314126.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2757..3632
                     /locus_tag="ACL3R8_001252"
     CDS             2757..3632
                     /locus_tag="ACL3R8_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR1314127.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3750..4613
                     /gene="pstC"
                     /locus_tag="ACL3R8_001253"
     CDS             3750..4613
                     /gene="pstC"
                     /locus_tag="ACL3R8_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR1314128.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4606..5421
                     /gene="pstA"
                     /locus_tag="ACL3R8_001254"
     CDS             4606..5421
                     /gene="pstA"
                     /locus_tag="ACL3R8_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR1314129.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5423..6175
                     /gene="pstB"
                     /locus_tag="ACL3R8_001255"
     CDS             5423..6175
                     /gene="pstB"
                     /locus_tag="ACL3R8_001255"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR1314130.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6190..6840
                     /gene="phoU"
                     /locus_tag="ACL3R8_001256"
     CDS             6190..6840
                     /gene="phoU"
                     /locus_tag="ACL3R8_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR1314131.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            6902..7333
                     /locus_tag="ACL3R8_001257"
                     /pseudo
     CDS             6902..7333
                     /locus_tag="ACL3R8_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7448..7582)
                     /locus_tag="ACL3R8_001258"
     CDS             complement(7448..7582)
                     /locus_tag="ACL3R8_001258"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314132.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(7747..7887)
                     /locus_tag="ACL3R8_001259"
                     /pseudo
     CDS             complement(7747..7887)
                     /locus_tag="ACL3R8_001259"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            8099..9115
                     /locus_tag="ACL3R8_001260"
     CDS             8099..9115
                     /locus_tag="ACL3R8_001260"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR1314133.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKPYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9137..10036
                     /gene="galU"
                     /locus_tag="ACL3R8_001261"
     CDS             9137..10036
                     /gene="galU"
                     /locus_tag="ACL3R8_001261"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR1314134.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10103..10780)
                     /locus_tag="ACL3R8_001262"
     CDS             complement(10103..10780)
                     /locus_tag="ACL3R8_001262"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR1314135.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10764..11303)
                     /locus_tag="ACL3R8_001263"
     CDS             complement(10764..11303)
                     /locus_tag="ACL3R8_001263"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR1314136.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11315..12445)
                     /locus_tag="ACL3R8_001264"
     CDS             complement(11315..12445)
                     /locus_tag="ACL3R8_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR1314137.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACL3R8_001265"
     CDS             complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACL3R8_001265"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR1314138.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13441..14352)
                     /locus_tag="ACL3R8_001266"
     CDS             complement(13441..14352)
                     /locus_tag="ACL3R8_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1314139.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACL3R8_001267"
     CDS             complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACL3R8_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR1314140.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALVPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17024..18280
                     /gene="tyrS"
                     /locus_tag="ACL3R8_001268"
     CDS             17024..18280
                     /gene="tyrS"
                     /locus_tag="ACL3R8_001268"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR1314141.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18358..20421)
                     /locus_tag="ACL3R8_001269"
     CDS             complement(18358..20421)
                     /locus_tag="ACL3R8_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR1314142.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20423..20701)
                     /locus_tag="ACL3R8_001270"
     CDS             complement(20423..20701)
                     /locus_tag="ACL3R8_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR1314143.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            20853..21701
                     /locus_tag="ACL3R8_001271"
     CDS             20853..21701
                     /locus_tag="ACL3R8_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR1314144.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            complement(22040..22255)
                     /locus_tag="ACL3R8_001272"
     CDS             complement(22040..22255)
                     /locus_tag="ACL3R8_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314145.1"
                     /translation="MCYYVKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFS
                     FRGSVWGLVLALYHLLFIDKFVISNRK"
     gene            22322..22894
                     /locus_tag="ACL3R8_001273"
     CDS             22322..22894
                     /locus_tag="ACL3R8_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314146.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACL3R8_001274"
     CDS             complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACL3R8_001274"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR1314147.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACL3R8_001275"
                     /pseudo
     CDS             complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACL3R8_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            28290..29561
                     /locus_tag="ACL3R8_001276"
     CDS             28290..29561
                     /locus_tag="ACL3R8_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR1314148.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29672..30964
                     /locus_tag="ACL3R8_001277"
     CDS             29672..30964
                     /locus_tag="ACL3R8_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR1314149.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            30966..>31208
                     /locus_tag="ACL3R8_001278"
     CDS             30966..>31208
                     /locus_tag="ACL3R8_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease"
                     /protein_id="HGR1314150.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIAL"
BASE COUNT         9504 a         6598 c         5929 g         9177 t
ORIGIN      
        1 agacttgata agaactctag agttagctcc ccatgttgaa ggtggctatt ttagacaaac
       61 aaaaaaagct tcagacacta taaaccttgc tggtaaggga agggcgcttt ataccagtat
      121 ttatttctta ttaagaagaa acgaatcctt cacattttca ccgattgaca gcagatgaaa
      181 tctggtattt tcatgcagga tccccactta ctgttcacat gatcacagca gatggtcact
      241 acgaagcagt cactttaggc ctggacatat ccaaagggca acaacttcac tactgtgttc
      301 ctaagggcac tatttgggga tcaacagttg ataaggatga tgctctggtt tcttgtcttg
      361 ttgctcctgg ttttgaattt gaggattttg aattatttga aagggtagat ctactggcga
      421 cctatccaga gcacaaggag atgattgagc gtttgaccag atactagtct tgataagcaa
      481 atttaatctg atttagcaat gttaggattt ctgataattg tgttataatg ttaccaatag
      541 gagataatag atgacaaaac aagtcttatt agtggatgat gaagaacaca ttctgaaatt
      601 gcttgactac catttaagta aggaaggctt ttctactcaa ttggtaacaa atggacggaa
      661 ggccttagct ttggcagaaa cagaaccctt tgattttatc ttgcttgata tcatgttacc
      721 acaattagat ggcatggaag tttgtaagcg gctgagagcc aaaggcgtca aaactccaat
      781 tatgatggtt tctgcgaaaa gtgatgaatt tgataaggtt ttggccttgg aattaggggc
      841 tgatgactac ctgaccaagc cttttagccc tagagaattg ctggcgcgtg tcaaggctgt
      901 cctcaggcga actaaaggag aacaagaagg agatgattca gataatatcg ctgacgattc
      961 ttggctattt gggaccttga aagtataccc tgagcgtcat gaagtctaca aggcgaataa
     1021 gttactgagt ttgaccccaa aagaatttga actcttgctc tatcttatga aacatcccaa
     1081 catgacactg actagagagc gtcttttgga acgtatctgg gggtatgact ttgggcagga
     1141 aacacgtttg gtggacgttc atattggtaa gttgagggaa aaaattgaag acaatcctaa
     1201 agcccctcaa tttattcgaa ccattcgggg ttatggttat aagttcaagg agttatagat
     1261 gaaacgctac cttcaatttt ggctagtcaa tctaagtgtt agcctcattc tgattgcagg
     1321 gatggcatta acttggatca gtaaaggcat cggtctcttt cttctagccc tttctttggg
     1381 acaaggtggc tactggctct tttgcctttg gaaatgggaa gttgcttttg agaccttgca
     1441 ccaacctctc ttgaccagta gtgaatactt tttagaaaaa gggcaagaag acttaaagtc
     1501 tttggctcag tatgtgtctg gcctaaaaac caaagtctcc caacaggatc agcaatacaa
     1561 ggacctagcc gaaacaatgg aggttcttct gtcgcaccta accatgggga cgtttttagt
     1621 ttccgctcaa ggtcagatgt tattatccag tcgctctctg cctcattatt ttcccgatgt
     1681 ggacggcgac ataagttcac ttgatgacct caaacggatg gatattcgaa atttagttca
     1741 ccaagccttt gatcaaaaaa caaggttaaa acaagaagta agtgggtttc atgagggtga
     1801 cttgatttta gaagtaacag cagttcccgt ttttagcccc acccaatctg tggaagctgt
     1861 gctcgtcttg ctatatgatt taacaacgat tagaacttat gaaaagttaa atttagcctt
     1921 tgtctcaaat gcctcccatg aattgaggac accagttact tcgattaagg gctttgctga
     1981 aaccattaag gggatgtcag ctgaagaaga agcgctcaag gatgactttc tagacattat
     2041 ttacaaagaa agtttgcgtc ttgagcatat tgttgagcat cttcttacct tatctaaggc
     2101 tcaacaaatg cctatacaat ggacgaccct ttctttggca gaatttgtac aggatttgac
     2161 tcaaagcttg caacctcagc tcaagaagaa ggatttacag ctaaaggtgc aggtgccaga
     2221 tgatgtcacc ctcgtatcag atagtcaatt actttcccaa atcttactca atcttttatc
     2281 caatgccatc cgttacactg aacaaggggg aaaaattgag gtcaagaccc aaaaggtgaa
     2341 cgaaggcatt aagatttctg tatcagatac agggattggt attagtcaat tagagcagga
     2401 tcgtattttt gaacgttttt accgagttaa taaaggtcga agcagacaaa ctggtggcac
     2461 tggtcttggc cttgccattg tcaaagaact cagtcaatta ttaggtggcc aagtcacggt
     2521 gacgagtcag cttggcagag gcagttgctt cacgattttt cttcctaacc aatctttcgc
     2581 acaggactaa taatttttaa agctattttt aggagcagcc atttttcaaa agtggctttt
     2641 tttgattctt tacacaatct ttacatgaat cagggataaa cctttacaaa gacttgttag
     2701 actataaatg tagtaagcct acacaagaaa aatacataga gataaaggtg attattatga
     2761 aattcaaaaa aatgcttact cttgcagcca ttggcttatc aggatttggg cttgttgcct
     2821 gtggcaatca gtcagctgct tccaaacagt cagcttcagg aacgattgag gtgatttcac
     2881 gagaaaatgg ctctggaaca cggggtgcct tcacagaaat cacagggatt ctcaaaaaag
     2941 acggtgataa aaaaattgac aacactgcca aaacagctgt gattcaaaat agtacagaag
     3001 gtgttctctc agcagttcaa gggaatgcta atgctatcgg ctacatctcc ttgggatctt
     3061 taacgaaatc tgtcaaggct ttagagattg atggtgtcaa ggctagtcga gacacagttt
     3121 tagatggtga ataccctctt caacgtccct tcaacattgt ttggtcttct aatctttcca
     3181 agctaggtca agattttatc agctttatcc actccaaaca aggtcaacaa gtggtcacag
     3241 ataataaatt tattgaagct aaaactgaaa ccacagaata tacaagccaa cacttatcag
     3301 gcaagttgtc tgttgtaggt tccacttcag tatcttcttt aatggaaaaa ttagcagaag
     3361 cttataaaaa agaaaatcca gaagttacga ttgatattac ctctaatggg tcttcagcag
     3421 gtattaccgc tgttaaggag aaaaccgctg atattggtat ggtttctagg gaattaactc
     3481 ctgaagaagg taagagtctc acccatgatg ctattgcttt agacggtatt gctgttgtgg
     3541 tcaataatga caataaggca agccaagtca gtatggctga acttgcagac gtttttagtg
     3601 gcaaattaac cacctgggac aagattaaat aaaatgtttg ctccataaat ctctaaagag
     3661 atgcagacgt ttcatcgtac aataagataa agaaggcaag tagggaggtg tcgtatctcc
     3721 cttactttct tcactagaaa ggacaagatg tgacaaaaca agccttcaaa gaagcagttt
     3781 ttagggcaat ttttttcatg agtgcaacag tagctgttgt agctattttg ctaatctgtt
     3841 tctttatttt tagtaatggc ttacctttca tagctaacta cggctttgcc cgttttttat
     3901 taggcagtga ttggtcgcca acgaacattc cggcaagcta tggtatttta ccaatgatcg
     3961 ttggttcctt attaattacc ttaggagcga ttgtgattgg ggtgccaaca ggcatcttga
     4021 catcggtgtt tatggtttat tattgtccaa agcccgtcta tggcttctta aaatcagcta
     4081 tcaacttgat ggcagccatt ccatctattg tttatggttt tttcggccta caattattgg
     4141 tgccttggat tagaagcttt ttaggaaatg gcatgagtgt cctaaccgct tcgttactat
     4201 taggaataat gattttgcca actattatca gtttgtcaga atctgctatc cgaacagttc
     4261 ccaaaacgta ttattctggt agcttggctc taggagctag tcatgaacgg agtattttta
     4321 gtgtcatctt gccagctgcg agatctggta ttttatcagc agttatttta ggaatcggtc
     4381 gcgcagtagg tgaaaccatg gcagttatct tggtggcagg caaccagccg attattccaa
     4441 gtggactctt ttcaggaacc agaaccttaa caaccaatat tgttctggaa atggcttacg
     4501 catcaggtca gcatagggaa gcccttattg caacctcagc agttctcttt ttccttattc
     4561 tcttgattaa tgcctacttt gcctacttga aaggaaaatc atcttatgag taaatacctg
     4621 ctaaaacttc tcgtttattg tttttcagct ttaacctttg gctctctctt tttaatcatt
     4681 ggttttatcc tcatcaaagg cttacctcat ctaagtctat ccctcttttc ttggacttat
     4741 acttctgaga acatttccct tatgccagcg attatttcca ccgttattct ggtctttggt
     4801 gctcttcttt tagccttgcc catagggatt tttgctggtt tttatcttgt ggaatataca
     4861 aaaaaagatt ccctttgtgt taaaatcatg cgattggcct cagatacctt gtctgggatt
     4921 ccttccattg tttttggtct gtttggcatg ctcttctttg tagtcttctt aggttttcaa
     4981 tactctctgt tatcaggaat cttaacctca gtcatcatgg tgttgccagt cattattcgc
     5041 tcaacagaag aagccctttt atctgttagt gatagcatgc gtcaagcaag ttatggactt
     5101 ggggcaggta agttacggac tgtttttaga attgttctac cagttgccat gccaggtatt
     5161 ttagctggag tgatactagc tattggccgt atcgttggtg agacagctgc cctcatgtat
     5221 acattaggta cctctaccaa tacgccaagt agtctcatgt cttcaggtcg ttctctagcc
     5281 ctgcatatgt atatgctgtc aagtgagggg ctacatgtca atgaagccta tgctaccggt
     5341 gtgattttga ttattactgt tttaatgata aatactctat caagcttatt atctcgaaaa
     5401 cttgtgaaag gagcttccta gtatgggaac attttcagtt agacacctag acttatttta
     5461 cggggatttt caagccttaa aaaatatttc gattcaatta ccagaaaggc agattactgc
     5521 cttgataggc ccatctggtt gtggcaaatc aacttttcta aaaaccctta accggatgaa
     5581 cgatttggtt ccttcttgcc atattgaagg ccaagtcctc ttagatgagc aagatattta
     5641 tagtagcaaa ttcaacctta atcagctacg taagcgtgta gggatggttt ttcaacagcc
     5701 taatcccttt gccatgtcta tctatgataa cgtggcttat ggcccaagga cacatggtat
     5761 tcgagacaaa aaacaattag atgccttagt ggagaaatct ttaaaagggg cagccatttg
     5821 ggaagaagtc aaagatgatc ttaaaaagag tgccatgtcc ttatctggcg gtcagcagca
     5881 acgcctttgc attgcgcgag ctttagcagt agaacctgat attctgttaa tggatgagcc
     5941 gacttcagcc ttagacccta tctccacttt aaaaattgaa gacctcattc agcaactaaa
     6001 aaaagattat acgattatca ttgttaccca taacatgcaa caagcttcac gtatttcaga
     6061 taaaactgct tttttcttaa caggagaaat ttgcgaattt ggagataccg ttgacgtgtt
     6121 taccaatcca aaagatcagc gcacagaaga ctatatttca ggacggttcg gataaggaag
     6181 gaaaaaccta tgagaaatca atttgactta gaattgcatg aattagaaca atccttttta
     6241 ggactagggc aacttgtcct tgaaacagct tcaaaagcct tactggcctt agcctccaaa
     6301 gacaaggaga tggcagagct aattatcaat aaggatcatg ctatcaacca aggtcaaagc
     6361 gctatcgaat tgacctgtgc ccgtttgttg gccttgcagc agccacaagt gtctgacctt
     6421 cgatttgtga ttagcatcat gtcttcttgt tcagaccttg aacgtatggg agaccatatg
     6481 gcaggcattg ccaaagctgt tttgcaacta aaagaaaatc aactagcccc tgacgaagaa
     6541 cagttacacc aaatgggtaa attatccctc agcatgctag ccgatttatt ggttgccttt
     6601 cctttgcacc aagcctcaaa agctattagt attgctcaaa aagatgaaca gattgaccaa
     6661 tattattatg ccttatcaaa ggaaatcatt ggacttatga aagaccaaga aacctcaatt
     6721 cccaatggaa cacaatacct ttatatcata gggcatctgg aacgcttcgc tgattacatt
     6781 gctaacattt gtgaacgcct agtctaccta gaaacaggag aactagtgga tttgaattaa
     6841 ttcaactaat ccttaaaaga gaagagtacg attaagtgct cttttttatg gttgtaaaaa
     6901 agttcatttg aacaatttaa gcagtgtaga tagtgaggag ctgtttcaat tctatcgtga
     6961 acgagggaat gctgaaaact ttatcaaaga aaggaaagca ggattctttg gggataagac
     7021 agatagttcg accatgatta agaatgaagt acgtatgatg atgggctgtc tggcttataa
     7081 tctctacctc tttttaaagc agctagctgg tgatgaagta aaggccttga ctatcaagcg
     7141 ttttcgacgt ctcttccttc atattgccgg aaaatatgtc tctactgcta gacgacatat
     7201 tctcaaattc tcaagtctat atgcctcttc aaaacagttt caagccttat ttgatacaat
     7261 ctgccagata aatctgatac tccctgttcc atatagagct agagggcagg ggaaaacatg
     7321 cctaacagaa taagtcacct tattttaaaa atcgagcatc aaaccaaggg aggagtctgc
     7381 ccttttttag gaaaaaatca agacaaatct cctcaattat gtctcgaaca tcagaaatta
     7441 agcaaaatca ccagaaggac agtatttcaa ctagcttttc tggtaatttt tgaactgtgt
     7501 agttcgttag tgccagatat gaataatttg ggatgataaa tctttcttcc tcaggtagcc
     7561 tatcataata ctcttcaaaa atcttatcaa aacactctct ttcttttggg cgatagtttc
     7621 atcttcgtat gtaggagtcc tcatcaagaa atacttcaat tctaggtatt ccttatccaa
     7681 ctctatataa cttggcatca acttgtaatc ttcaaccccc aaacgttcag cgatatattt
     7741 taactttgtt agtgttggtc tggattctcc attttcaatt ctaattaatt gacggatact
     7801 taattcagac tcatcaccac aaaattctga acgactgatt tttttagcca aacgtaatct
     7861 tttaattttt tcgccaaact ttcgcaacct acaagaacct cctgagttgt ttacctctat
     7921 ttatagcata tactgaatca aactatctat cagatttctt ctcactttaa ctaaagacta
     7981 agagtttatc ccttcatctc gatctttgtg tatttttcca ccatacccca gtaatgcaag
     8041 tgcaaaatcc cctagaatat gatataataa gagaaagaaa tctatcaagg aggaaatcat
     8101 ggaaaaacaa accgtcgccg tcttggggcc tggttcttgg ggaaccgccc tttcacaagt
     8161 cttaaatgac aatggacacg aggtacgtat ttggggaaat cttcccgagc aaatcaatga
     8221 aattaataca caccatacta ataagcccta ctttaaagat gtcgttctag acgaaaatat
     8281 cattgcctac accgacttag cagaaacatt gaaaaatgtg gatgcgattt tgtttgttgt
     8341 cccaacaaaa gtgacacgac ttgttgccca gcaagttgca caaaccttgg accataaggt
     8401 tatcatcatg cacgcatcaa agggattaga acctgatagc cataaacgat tatcaaccat
     8461 tcttgaagaa gaaattcctg aacatctccg tagtgatatc gtcgctgttt cagggcctag
     8521 tcatgcagaa gagaccattg tgcgtgacct aactttaata actgctgctt ctaaagattt
     8581 acaaacagct caatacgttc aggagctatt tagtaatcac tacttccgac tttataccaa
     8641 tacggatgtt atcggggttg aaactgctgg tgctcttaaa aatattattg ctgtcggtgc
     8701 tggagcttta catggtcttg gatttggtga taatgctaag gcagccatca tcgctcgagg
     8761 tttagcagaa atcacccgcc taggggtagc actcggggcc agtccattga cctatagcgg
     8821 cttatctggt gtgggagatt tgatcgtaac gggaacttcc atccactctc gtaactggag
     8881 agctggagat gctctcggac gaggagaatc cctagctgat atagaagcta atatgggcat
     8941 ggtaatcgaa ggaatttcaa cgactcgagc agcctatgaa ctagcccaag aacttggagt
     9001 ctatatgccc attacacagg ctatttacca agttatttat cacggaacca atatcaaaga
     9061 tgccatttat gacatcatga acaatgaatt taaagcagaa aatgagtggt cttaaccctc
     9121 tatagaaagg atttttatga catcaaaagt tagaaaggca gttatccctg ctgctggact
     9181 aggaactcga tttttaccag caaccaaggc ccttgccaaa gaaatgttgc caatcgtaga
     9241 caaaccaact atccagttta tcgtggaaga ggctctcaaa tcaggtattg aagatattct
     9301 agttgtcact ggtaaatcaa aacgttctat tgaggaccac tttgattcaa actttgagct
     9361 tgaatacaat cttaaggaaa aaggcaaaac ggatttgtta aaattggtag atgaagcaac
     9421 tggcatgcgc cttcatttca tccgccaaac tcaccctcgt ggtcttggag acgctgtctt
     9481 acaagccaaa gcttttgtag gaaatgaacc cttcgttgtt atgctgggtg atgacttgat
     9541 ggacatcaca gacgagaagg ccgttccttt gacaaaacaa ctgatgaatg attacgaaaa
     9601 gacacacgca tcaaccattg ctgtcatgcc cgtaccacac gaagacgttt catcatatgg
     9661 agtcattgct cctcaagacg aaggaaaaga tggtctttac agtgttgaaa cctttgttga
     9721 aaaaccagct cccgaggaga ctccaagtga tttggcaatc atcggtcgct atctactcac
     9781 accagaaatt tttgagattc tcgaaaagca agctcctggt gctggaaatg aaatccaact
     9841 tactgatgca atcgatactc ttaataaaac acagcgtgtt tttgcccgta aatttacagg
     9901 agctcgttac gacgttgggg ataagtttgg ctttatgaaa acatctattg actacgccct
     9961 caaacatcca caagtcaaag atgatttgaa gaattacctc atccaacttg gaaaagaatt
    10021 gactgagaag gaataaaata aaaagataag gttcaaaaaa tgccttatct tttttcatta
    10081 cacaaatttt ctttcaactt cgtcacattc ccattccctt gtagaaaagc aaaatggcga
    10141 gtcctacgaa caagactacc gctcctaatc tctggctggt gttatacagc cgtttttctc
    10201 ctctaactgg aaagataact gctagaaatg cgccaccaac tgctccaccg atatggcctg
    10261 ctaggctgat ccctggaatc agaacacttc caataatgtt aaccacaaaa agtgtcatat
    10321 aggattggcc caactgctgg atataaggat tacgcgttgc atagcgaaga atgataatcg
    10381 cggcaaatag cccataaaga gaggtagagg cgcctgctgc taaggattta ggactaaata
    10441 caaaaacaaa gagattgccc atcattcctg ataagagata gagaaaaaag aactgcttag
    10501 agccgaaaat ctcctctacc tgccttccaa gataataaag tgaaagcata ttaacaatga
    10561 aatgttccca cccaatatga acaaaaatgg cagacaagag acgccaaacc tgctcgggaa
    10621 agaggcgaat agctggccca tacatggctc caaatcgaaa taatgtatct gccctgtcaa
    10681 agtttccgcc tgcagtgacc aacattagta aaaataccaa ggccgtcact aagaggaaga
    10741 aactcgtcac agggtaacgt ctatcaaaga tttccttcat caattaatac ctcctgaaca
    10801 ggaatatcat ggttttcagg tataaagtcc tgaatttgac aaggatgaac cgtactcaaa
    10861 gtatgaccag aaaaatgttc cagatagcgg tcataataac ctccaccata tccaatccga
    10921 tatccatccg tcgtaaaagc caggccagga acatgaatca aatcaatctg agatacatcc
    10981 accacttcca aatctccctg tggctccagt aaggcaaagg cagtttttac caactgctgc
    11041 agatcataga ctacaaagtc catgcgcccc ttgggataag ttttgggtat taaaaccttc
    11101 ttgccgtcct tcagcgcctg ctcaatcagt tcccgcgttt gaaactcatg agaaaaagag
    11161 aggtaggttg cgatgacctt ggcttcttga taaaaggggt gttgtaaaat tcgctcggtt
    11221 aaagcttggt ctatagcctg tttttgttct tgagataaag ccttcatttc atgcaagact
    11281 tgcttgcgta attccgattt catagacaag ccctctattc tgctgccttc tttttcagga
    11341 aactagacac cgcagccacc ccaatagcta agacttcttc cttaggactc atttgagggt
    11401 gatgaagagc gtagggacta tcgataccta gccaaaacat cacgccatca acctttgaaa
    11461 ggagataacc aaagtcctcg cctgtcatag caggttcgat atcaatcaac tcgattccgt
    11521 ctttctcgtc aaagaagtcc atcagttcac gcgccaaggc tggattgttc tcaacaggta
    11581 ggtatccacc ttgtttgagt tccacttcga cttccatatc aaaggcagct gcaacccctt
    11641 ctgcaactgt ttttaccctc ttttgcacca agagactcat gtcctgtgtc aaggcacgaa
    11701 tagttccatg taaaaaagct gtgtctgtga tgacattgtt ggtggttcca gcttgaaaaa
    11761 cgccgaaggt caccactgct ccctcgattg ggttgacatt gcggctaaca actgactgca
    11821 cttgggtcac aaagtaacta gccgccacca aggcgtcatt ggcttcatga ggaaaagctg
    11881 cgtggccacc tttgcctttg aaacggatct tcacctcgca agttcctgca aagagtgtat
    11941 gagtattagt cgcaatctgg ccgactttca aatctggacg aacatggaga ccatagaatt
    12001 ggtttggcaa ccaatctcca aaagcaccag cctcatacat gagcatacca ccagcttcat
    12061 tttcttcagc aggctgaaat agaaagagca gattattttt aggttgctcc tcaagggcgc
    12121 gctcaagaca gcctaaggca atggtcatat gaaaatcatg gccacaggca tgcatgcgac
    12181 cttggtgttg agaagcaaaa ggtagacctg tttgttcgac gataggcagg ccatcaatat
    12241 ctgtccgcca accaatggtt cgctccggct gacttccctg caggtagacc aaaatccctg
    12301 tccgccaagt acgaatttga acaaaatcct tgcccgtagt caatttctca atcacatcca
    12361 gcaaataagc ctgagtcttg aactcctcca agccaatctc tggtatctgg tgtaaatctc
    12421 gtctagtctg aatcaaatct aacatctatc tgtcctccga tatagcagaa agaggctgga
    12481 aaaagggttc cgcctctttt ttacttttac aattacaagg tacgaagcgc atcctctagc
    12541 gctgtttttt gttgagtttg ggcatcaatt tctttgatga tacgagctgg aacacctgct
    12601 actaccacgt tttctgggac atcttgggta acaatagctc ctgctgcgac aactgaacca
    12661 ctaccgattt ggactccttc gataaccact gcattagcac cgataagaac attgtctccg
    12721 acacggactg gttcagcact agctggctca atcacacctg ccaaaactgc acctgcacca
    12781 acgtggctat tttttccaac gatggcacgg ccaccaagga tggcacccat gtcaatcatg
    12841 gttccagcac cgatttcagc accgatattg ataacagctc ccatcatgat aacagcattg
    12901 tcaccaattt ccacctggtc acggataata gcacctggct cgatacgagc gttgatagca
    12961 cgcttatcta gcaaaggaac tgcagaatta cgagcatctt gctcgacaac ataatcttga
    13021 ttttctacca aaccttcaag aagcggagcc acgtccttcc agtctccgaa taggacattt
    13081 cctagtttga caacagagct aggcacagca gttgcgagtt gcccctcaaa ggttactttg
    13141 acactggttt tcttttcagc attggcgata aattggataa tttcttgagc gttcattttt
    13201 gtagcagtca taggtgcctc ctggttcgtt ataatgatac ctattctacc aaaaaaggcc
    13261 tcaaatttga aacctttttg tctgttttta ggtatgattt tttagggatg tgagataaaa
    13321 cgtgctgtcg gtaaaagcaa gcccctaccg atacaaccta aaaacactct tcacaactat
    13381 ctccccgtgt tttattgact attctagtat agcacacttt tagaattaag aaaagacttt
    13441 ttatctactt tctttcgctt cttctataga caaaaatatc atgggtaaaa taatcaaggc
    13501 tatagctaga aggagggacc aatccactac taatcctaag aacaaaacac tcaagagagc
    13561 agaagagaga ggttcactgg cactgataac ggaaaccacc aaaggagaaa ccaaggacac
    13621 agccttcatg gaaatgaaaa aagcaaaagc cgttccaaag aaagcgataa tgaggcaaat
    13681 caagatactc caaatatcaa gagtaaagga aagctgataa accggcgaga ggacattgct
    13741 aaacaaacct gccaaaatca tcccccaccc aaccgtagga acaaaaccat aacgcttagc
    13801 aaaaggttgg ggcaagataa cattaaacat aacacccatg gcactcagca aacctgttat
    13861 aagagctagc ggcgtcatgg ataactgaga gaggtctccc tttgtcgcca tcaagcaaac
    13921 acccagcatg gcaaccaaaa catagaaaac agcgcttttt gacgctcgtt tttgataaac
    13981 caagcgattg taaaagagga taaagacagg gctaataaac tgtaaaatag ttgctgtcgt
    14041 agcatttgag tattctacac agagatagaa aaaatactga actgaaaaaa tccccaaaat
    14101 agcataggct aaaaagggca ggtaattttt cttgtctcgc caaatatcta gcacttgcga
    14161 ttttaattgt attgcagacc aaatgagtac aagactccct gccagtgtca aacgcataga
    14221 ggtaatccag cccgaagaca cctgataatg agtaaagaag tactctccta aaattccaca
    14281 gattccccat attaagccgg ataggagcga ataaattttt ccgttaacaa tctttttctg
    14341 atactgattc atacccttat tgtaacacga aaggaaaaaa gtggcaatcc attgattggc
    14401 cacttcattt agagaattat cgtctcgccc ttgaagaaga aggtcgtgta gtacttgagt
    14461 tactgctatc gctagaacta ctacttgaac tgctggagct ggatggagtt ggtagactcc
    14521 ccacaatact agaccaagca ttctgataat ccgcatcact tccgccaata gcaaagcgat
    14581 aacttgtcgc tggcgctcct gacttattag cccaatagct ggtaacagtc gaacctgtga
    14641 cctctacttc ttttccttca acagaaacct tccctggttt ttgacctgtt gatttcaaga
    14701 cttccgattt cactacacta ggaactaaag caaagcgctc gttcccccaa atgcttgggg
    14761 aagcttgctg aatcgcattt actagatgag ccatgtaatt agagttatta gaataacctg
    14821 ctctacgtga caatgaatga ttatcatcat gcccaatcca gccacctagg gttaatctag
    14881 gtgtcgaaag catgagccac atattttcgt cttggttggt tgtaccagtc ttcccaatcc
    14941 aatctgcatt agccagagta ggatttaaag aagtcaggtt agacttgaag gttgttgtca
    15001 cacgagagga tagaacttct cgtagcaatc cctgcataat cgtcgcagta gcttttgaat
    15061 agacttgaac cggtttatcc tgatactcat acaccactct accatctgct gcttcaatct
    15121 ttgaaatcac atgcttctga tgataaactc cattattagc taaggtctga tagccattgg
    15181 tatgctgggc aactgtgact tcaataccac cacccattgg caagctctca ataccgtact
    15241 caggaatctc gtaacccatc ttttccatat aacccttgac atcaacaccc ttttcacgga
    15301 gcatacgata ggtccagtaa gcagggatat tccatgaata gttcagagct tctcccaagg
    15361 tcatcattcc tgttcccttg ctattagcat acataatcgg attgccatta gcaaagtttg
    15421 ttggatagtt agatagaatc gtttcacttc ccatcaagcc ctgatcaata gcaataccgt
    15481 aggccagcaa gggcttggta gtagaagctg gcgaacgttt ggtatcaaag gcatgattat
    15541 tttgattttc ttgataatta cgaccaccta caaagcctag aatagcacct gtttggttgt
    15601 ccatcaagac attccctact tctacacgac ctgttccatc gtctaaaaga tagccataat
    15661 cagcaaccgc actttgcatg gcagaatgaa ttttctgatc tatggtagta gtaatcttat
    15721 aaccaccatt ttcaatttcc ttggctgcca aatctcgata aaacttctga gttgcctcat
    15781 ttttcaactc cttagcggag acattgtctc tctgagctag atagtcatac atacgttctt
    15841 gagcttctgc caaagttgta aagtataaat agtctcgtga aattcctgta acagtgcccg
    15901 atggtaaaaa gtcctgttta aggtcataat ccttgtactg agaatactcg tctttgctta
    15961 atgcacctgt acgatacata ctgtaaagaa ctgccttagc ccgtcttaag ccaatttcta
    16021 ggtcttcatc actcttcaac tccccagtat tttcataagg agagtaagta atgggactct
    16081 gtggaagtcc tgctaaaaat gctgcttgag gaacagtcaa ctgactggca tctacaccga
    16141 aaattccctc agctgcttgc cgagcccctg caatattctg tcccttatta tttcggccaa
    16201 agggagccac attgagatag gtcgttaaaa tctcatcttt attcatggcg cgttccaagg
    16261 caagagcatc cacaatctct gccgccttac gagccaaggt cggcgcatcc ccaaccacct
    16321 gctgtttaat tagttgctgg gtcaaggttg aacccccact agaggaaccc aaacctacaa
    16381 atttccccaa ggtcgcacga atcaccgcct tgggtactac acccttatgt tctttaaagt
    16441 gttcatcttc tgtcgcaatg atagccttct tcagattttc cgaaatttgc tcagatgaga
    16501 tagaagtgcg caacaaatca ctctctatgg aagcaatcac cgtcccgtcc gaataggtaa
    16561 tctctgaaat agaagagatg tccttgacct gattcaccaa ttcttctgtc tgaggcaccc
    16621 gaaccttgtc aaataaggcc actccgtacc ccaaagcaat cccagctccc aacattcctc
    16681 ctagaaaacc gagtacaaag agtaagttaa ataaggcttt tatactcagt aaaatagctg
    16741 ggaaaatggc tgacttatct aaggttttag attttttggt acttgaacct ttcttgccag
    16801 gtctagctga ttttttattt ttttgttttt gctggaaaaa ttccagcatt tttcgtttta
    16861 attcatttaa ttgattttgc atggatttcc tcactctatc tattatacca caaaagggaa
    16921 attttcaata aaatagccac tttcttccct attctgctag gctattgccc aagtttgtga
    16981 tacaataggt agaaacaata attttaaaaa ggagaaaaga cacatgcaca tttttgatga
    17041 gctaaaagag cgtggtttga tatttcaaac gactgatgaa gaagctttgc gtaaagccct
    17101 agaagaaggt caagtttctt attatactgg ctacgatcca actgctgaca gccttcacct
    17161 aggccacctt gtcgcaatct tgacaagtcg tcgcttgcaa ctagcaggtc acaaacctta
    17221 tgcgctcgtt ggcggtgcta caggtctcat cggagatccg tccttcaaag atgctgaacg
    17281 tagtctccaa acaaaagaca cagtagatgg ctgggtcaag tctatccaag gacaactttc
    17341 tcgttttctt gactttgaaa atggcgaaaa caaggctgtc atggtcaaca actacgactg
    17401 gtttggcagc atcagcttca ttgacttcct ccgtgatatt ggaaaatact tcacggtcaa
    17461 ctacatgatg agtaaggaat ctgttaaaaa acggatcgaa acaggaattt cttacactga
    17521 gttcgcttac caaatcatgc aagggtacga cttcttcgtc cttaaccaag accataatgt
    17581 cactcttcaa atcggtggtt ctgaccagtg gggaaatatg acagctggta ccgaattgct
    17641 tcgtcgtaag gcggacaaga ctggtcacgt tatcactgtt ccactaatca cagatgcaac
    17701 tggtaagaaa tttggtaaat cagaaggaaa tgccgtctgg ctcaatcccg aaaagacttc
    17761 tccatacgaa atgtaccaat tctggatgaa cgtgatggac gctgacgctg ttcgcttctt
    17821 gaaaatcttt actttcttgt cacttgatga gattgaagat attcgtaaac aatttgaagc
    17881 agcgccacac gaacgcttgg ctcaaaaagt cttggctcgt gaagttgtta cacttgttca
    17941 cggagaagaa gcctacaaag aagcacttaa catcactgag caactctttg caggaaacat
    18001 caaaaacctt tctgtcaaag agctcaaaca aggacttcgt ggtgtgccaa actaccaagt
    18061 acaggcagac gaacataaca atatcgtgga actgctcgtc tcatctggta tagttaactc
    18121 aaaacgccaa gcccgtgaag acgtccaaaa cggagccatc tacgtaaacg gcgaccgcat
    18181 ccaagacctt gactatgtct tgagtgacgc tgataagtta gaaaatgaac tgactgttat
    18241 ccgtcgtggg aagaaaaaat actttgtatt gacttactaa actattcaac atttatctat
    18301 aaacaaagga gttaacctcg agaaaggtaa ctcctttttg ctgttaataa ctctcatcta
    18361 tctattttta atagacaagc tacgcaagac aatgcgcaag gttgttagat tatgtaagat
    18421 agagagattt gaaggactga accaattaaa taagccaaag ccaatcaaac tactatttac
    18481 gacaacggta tcttgaatat ttttcttgat gagtgtttgc aaagatgatg ataacgaatc
    18541 caactcttgg aagaaatcca aacgattatc taacaataag atatcactca tctgcttaga
    18601 aatatctgca ctctcattca tcaccacacc gatatctgat agagttaaag ccgctgagtc
    18661 attcaatcca tctccaacca tcaaaatagt gtgacctgct ttctgcagtt tctctactaa
    18721 ctcaaatttc ccatcaggtt tcaagtctgt atagacctga tcaaagggca aatctttgac
    18781 taattcctct gtcctaatca aggtgtctcc tgttgccaga atcaattttt tcccctgtgc
    18841 cttaagttta tccaaggctg tttttgcttc ttttctcaaa ggagtatgaa tgcagaacat
    18901 tccaatcaat tcattttgat aagccaagaa taagagattg tagtgactct tgtactcttc
    18961 aattaaagca ttttgttctg aactgatatg aatctgctca tcctgcatca agacataatt
    19021 cccaataaga actggttggc catctatatg agatttgatc cccttgcttg cgatatattg
    19081 gagtttccca tgcatttcct catgttcaat tccctctatc tcagcttgct tgacgatggc
    19141 attagcaata ggatgataaa tgtgttcctc aagacaggca ctgattctga gaatatcttc
    19201 ctcactatag tctccaaaag gtaacacctt ttcaactata ggataactag ttgtgattgt
    19261 tcctgtctta tcaaacaaga aagtatcaac ttccagatat ttctccagaa catctccatc
    19321 cttaatcacc atttcacggt tcaacccctc cttgataact gtcaaataag ctacaggagt
    19381 agagattttc aaagcgcagg agaaatcgac caataggaaa gaaatagcct tagaaaaaga
    19441 acctgtcaat aggtaagtca gcccagcccc caagaaatta tatttgacga ctttatccgc
    19501 catcttgatg aaatagcgtt gtttcgtttt cttgttttct tcagatttct tcatcaactc
    19561 aatcagctgt aaaatacggc tgttcatctg attatctgtt acacgaatgc gtaactctcc
    19621 agtttctaat actgtatttg cacaaaccaa atcagactct cttttttcaa ctggaaaact
    19681 ctctcctgtc aaggaacttt cgttgaccat acctaaacct gaaactactt gcccatcaaa
    19741 cagaatttca tttccttgag ataagatcaa gacatctcct atttgaacat cggaactctt
    19801 tatactaaca accgtatcgc cctgtactag gaatacatcg ctctcttttg caagaagact
    19861 ctgttctaaa tctgttgcag tttttttcaa ggaccactga tctaaatgat tccccaaatc
    19921 aagcataaac atgatattgc tagctgtctt ggattggttc ataaacaaag acaataaaat
    19981 agccgaacag tccaagactt ccatagttag ttccttacgc gctagtgttt gataggcttc
    20041 tctaatataa cccaaagcct gataacaagt ccatatatag cgaataggat acggcacaaa
    20101 actacgaaaa agtacacgct taaccgctgc acctgaaaca atagaataag cactctcttc
    20161 tctacgaatg ggaagagtca tcaactcaga aactttccct ttatcaattc tttttaaaaa
    20221 ggcttctgca ttatctaata cagaaaagcc ttcttttatg cgtagagtaa agtgctgttg
    20281 atccatgtaa aactggatag actcaatccc cttttcatct ctcgccaagg aacgaagata
    20341 gtcttgaata tccaaggtaa gtgaaaaaga agatgatagt cggatatgtt ggtatcctct
    20401 atgtagcact ttaaaagaca tattattcac ctataaggct atctaattgc tcttcttttt
    20461 tctcttgctc gtacaaatat ttggcatctt gcaagacatc gtctccatgt tgcttcacaa
    20521 cagaaacaga tgcatctagc tcgtctttca acttgtaagc cttagccaaa gctttagaat
    20581 aacctttttt agcttcctta cttgctaaga ttttcaaacc aagggtacca aatgcgacac
    20641 cacccaaaaa taatgaagat tttttcgcaa cttttgcaac ggttaatact tcttttaaca
    20701 tacttatttc ctccttatca ttattatata gcaatttaga tataaaagca atttcattct
    20761 ataaattgga gaattagttt tatttctact gaatctccca tctacttatt cctaaagttg
    20821 ctttcatttg cctcttttga tacacttaaa ctatgaatac aaatctcaag cccaaacttc
    20881 agcgttttgc ttctgcgact gcctttgcct gtcctatctg tcaagaaaat ctgactctgt
    20941 tagagactaa tttcaagtgc tgcaaccgtc attcttttga cttggcgaaa tttggctatg
    21001 tcaatctagc acctcaaatc aagcaatctg ctaactataa caaggaaaat tttcaaaacc
    21061 gtcaacaaat cctagaagcc ggcttttacc aagctatctt agatgctgta tctgacttgc
    21121 ttgcaagctc aaaaactacc acaacaattt tggatatcgg ttgtggtgaa ggattctatt
    21181 ctcgcaaact acaagaaagt cactctgaaa aaactttcta tgcctttgac atctccaaag
    21241 attcagtcca aatcgctgct aaaagtgaac ccaactgggc agtcaattgg tttgttggcg
    21301 acttggcacg acttcctata aaagacgcta acatggatat tctgcttgat atcttctcac
    21361 ctgccaacta tggagaattt cgtcgcgttt tatccaaaga cggtatcttg ataaaggtta
    21421 tcccaactga aaatcacctc aaagaaatcc gtcaaagagt acaggaccag ctgacaaaca
    21481 aggagtattc taaccaagat atcaaggagc atttccagga acactttacc atcctatcta
    21541 gtcaaactgc ctctctgact aagactatca cagcagaaca actccaagcc ctactcagta
    21601 tgactcctct cctctttcac gttgaccaga gcaagattga ctggagccaa ctgacagaga
    21661 ttaccatcga agcagagatt ttggttggga aagcattcta aactagactt cccaaaggta
    21721 taaaacttac cgaaaatctt caatattata aaaacgcata agaacaggta cacaaacctt
    21781 aatcttatgc gttttgttat agtttccata cacattaagg ggaaatagtt gaaatcagtt
    21841 ctcttaataa ccattgaata ccatatacta catttacccc aaatatgata taggccgtat
    21901 aaatcaagta tttcgatttc tcccgtctca aagaataaat cttgtacaaa atagataaat
    21961 ttaaaataat aaataataga gacaaaatct tcctccaaaa tcaatattaa aagtagccag
    22021 tcaatcatag ttctaatctt tattttcgat tcgaaattac aaacttatca atgaacaata
    22081 agtgatataa ggccagtacc agaccccaaa cgctaccacg aaaagagaat tcttgatgat
    22141 tgagagtaaa caaatcatgg ttaccaatat agaggcaggt caaaataaca aataaaatcc
    22201 aaaataaatc cgtccattta tattttgaaa aatatttttt aacataatag catatttttt
    22261 tgactataat aacagtatat gataaaatgt aagcagatac aaataaaaag gagaaaagct
    22321 catgaacaaa ttaatgaaat ttatttcggt ttttttgacg tcaattgtgt taattgtatc
    22381 agcgattcca agtgtttcag ctgtatacgc ttctgaacaa gtatcacaaa ttgaaacaaa
    22441 tatggaactt caacctgtca cttctctaac agaagaacaa atcaatacac ttgcaaacga
    22501 aatccaatct tttcatccag acgtctcaca acaatggatc aaagaagtaa ttaaccgaca
    22561 attacaaggc gattatacaa tcccacctac atactctcca tttagagcag cttggcaagg
    22621 tattacagtt aatcaaatgg gtgctctatt agatactgca atagctttag cattaggagg
    22681 aactactgca ggccttgcaa atctaattaa agtaaaagga aaacatgcag caaaaagtgc
    22741 tattcgttca gcaatttcta gatatctagg tagttggttt gtaaatgatg ttgctttaga
    22801 attcgctatg aatttattat caccggggat ttatttagca caattatggg ataaaaatga
    22861 tgccattcct aacaacggaa ggattaactt ttaatcatga gatatacaat aaaattaatt
    22921 gggtataacg tattttcgtt gtttatattc tttatcttat caatgttgtt taaagttccc
    22981 tttaggtggt ggatcagcat tgcaatgacg acttcgtcgt acattgtata taattactta
    23041 aagaaaaaga gagaaaagga atgatcttat accagatcat tccttttctg ctttctgtaa
    23101 atccctcgga gtgtgtttgg cgctttgata cgaagtgtca aagctgtata aacgttacta
    23161 tttccaaaaa agtaacagaa aattcctgct ttgtaggact gctttgggtg agtaatagac
    23221 atgtagactc accctatctc ctgatggcga aaagaattta gcaatgatgc aagttgttct
    23281 gaactcgaga aaaaacatgc cgaaatcgaa gaaaagcgtg cagaacttga agcgaagaag
    23341 caagaaatgt tgaagctctt ggataaatag aatttagaaa acagaaaaaa ctaaaaaaaa
    23401 tgtagggttt atttccctac attcttaaaa taacttagta cataaatgac aatgctgcca
    23461 ctgccgtcaa tattgcaaaa actattttcc aaattttttt attttttcca aaaatcttat
    23521 caggtaacaa gcttattaca agaaaggtaa taaacaacac caatttaagt gtgtatatca
    23581 taaaaacacc ttctttccta caattatatt ataatacttt atgtaagcga atataataga
    23641 tgtgaggtaa ccaactacga aaaaatataa ggctgaagac agtaaaaacc agcatttaaa
    23701 gccttcactg tatctaggat ttccctattt ttagacaaga ttgacccaaa tccacagcat
    23761 ttaaaaaagc gaatttcaat tgaaactcgc ttttttacaa gatgtattag tataaatttg
    23821 tatcttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    23881 gcaccgcttt gaggttgcag ataaagctga cgtggtttga agagattttc gaagagtatt
    23941 agttcaagtg ccagatgtct tcgttatact gagcgattgt acggtcagat gagaagaatc
    24001 ctgctttaga aatgttaacg atgactttat ccaaccatgc gtcacggtct tcgtagtcag
    24061 caagcatttg ctctttgact ttgatgtagt cttccaaatc aagaagagtc atgaaccagt
    24121 ctttgttgat caattcattg taaagacgtt ccaagcgctc tttgtttcca gctgcaagaa
    24181 ctgcatcact aacgatgaag tcaaccaatg gtttgatagc ttcacgagcg tagaattcgc
    24241 ttgatttgta agctgctttt gcgtaaaggt cgataacagt ttctgaattt tcaccgaaga
    24301 tgtagatgtt ttcttctcca accaactcag cgatttccac gttagcaccg tccatagtac
    24361 caagtgtcaa agctccgttc aacatgaatt tcatgttacc agtacctgaa gcttctttag
    24421 aagcaagtga gatttgttct gagatatcac atgctgggat aaggaaactt gctgcagtaa
    24481 cgttgtagtt ttcaaccata actacttgca agtgtggagc tactgctgga tcgttagcaa
    24541 taacttctga catgcaaagg attaaatgga taatgtcttg agcgattgtg taggctggag
    24601 ctgctttacc accaaagaag attgtgattg gacgagcagg gatgttacca gctttgatgt
    24661 caaggtattt gtggatcacg tacaaagcgt tcatttgttg gcgtttgtac tcgtgaagac
    24721 gtttgatttg gatatcaaag atagaatttg gattgatttc cacaccttgg tgttctttca
    24781 agtgacgagc caatttacgt ttgttgtgag ccttgatgct ttccaatttt tctttgacag
    24841 ctgctttgtc ttcataagac aacagttttt caagctcatc tgcttcatgg tgccaaccat
    24901 ctccaagaat ctcatccaag tagtgagaca atcttgggtt agcatgcata agccaacgac
    24961 ggaaagtgat accgtttgtt ttgttgttga acttttctgg gtaaaggtcg tagaaggctt
    25021 tcaactcaga atttttcaag atttcagtat ggagtgctgc aaccccgtta acactgtatc
    25081 cgtagtggat atccatgtga gccatgtgaa cacgtccgct ctcatcgatg atttgaacag
    25141 ctggatcttt gtactctgcc ttcacacgac ggtccaattc ttcgatgatt ggtaccaagt
    25201 gaggaaccac ttcttgcaag aattcaagag gccatttttc aagcgcttca gcaaggattg
    25261 tgtggttagt gtaggcagtc atgctacgaa caattgagat tgcttcgtca agatcgatac
    25321 cacgtgcagt caaaagacga atcaattcag gaatcaccat tgatgggtga gtatcgttga
    25381 tttggacaac tgcgtagtca gcaaggtcat gcaagttgct tcctttttcg attgcttcgt
    25441 cgatgatcaa ttgcgcaccg tttgaaacca tgaagtattg ttggaagata cggagcaatt
    25501 caccttgacg gtcactatca tctgggtaaa ggaagagagt taagttgcga gcgatatctg
    25561 tcttgtcaaa gttgatacca tctttaataa tagaagaatc aactgaatcc aagtcaaaca
    25621 aacgcaagcg gtttttagtc gctgtttcat aaccagtaac atcaatatcg taaagagttg
    25681 atgtcaaagt aaagtctgca aatggtactt ggtagctacg gcttgagcga accaaccagt
    25741 tttgctctgt caaccatgca tttggaattg tttcttgttg gttgttttta agaacttgtt
    25801 ggaaaagacc aaagtggtag ttaagaccaa caccgtcacc attcaaacca agagtagcaa
    25861 ttgagtcgat aaagcaggca gccaaacgtc ccaaaccacc attaccaaga gatggttcca
    25921 attcaacttc ttcaacttcg atcaagtctt tacctgcagc tgcaagttct tttttaacat
    25981 cgtcgtaaag accaaggtta atcaagttgt ttgacaagag tttaccaatc aagaactcag
    26041 ctgagatgta gtaaactttt ttcttaccag tgttgactgg tttttggctg cttgcaagct
    26101 tgctgtagtt aagaagagca aggtaaagct cttcattgct acattctgca atggttttat
    26161 tgtaacgatt ttgtacaaat tcttgtagtg ataacatgtt tagttgtctc ctgattattg
    26221 tcttatttct ttaaatctac caaattttca ttaattcggc gataaattgt tgtcaagtca
    26281 agcaaacctt cctcgacagc tggtgtcaat tgatcttcag tcatacgcca agaccagttt
    26341 ccaccaaggg tagatgggaa gttcatacga gctgcctcat ccaattctag taaatcttgc
    26401 atagttgcaa ttgccataaa gctaactgat gaaaatactg tacgaagcat agcgtgtacc
    26461 actgtttcgt attctttacg gttcgtgtaa cgagccatgt actcacgagt cgcatcatca
    26521 atctcattac ggtaccaacc aagaaccgta ttgttatcgt gtgttcctgt gtacataact
    26581 gagttagcag gtgccaagtg tgggctatca atgctttcgt cttctgggtt gaaggcaaat
    26641 tgaagaatct tcattcctgg gaagccagta cgttcacgca attcgatcac ttcatctgtc
    26701 atgaagccaa ggtcttctgc gatgatgttt agctcaccaa gttcttcctt aacggctgca
    26761 aaaagcttgt agcctggacc tttcacccac tcaccaggtg ctgctgtatc ggaaccagca
    26821 gggatttccc agtaagattc gaagccacgg aagtggtcga tacgaacgat atcgtagatt
    26881 ttgaagcttt cacgcaagcg ttcaatccac catttgtagc cgtctttgtc cattgcttcc
    26941 cagtcataga ttgggttacc ccaaagctga ccagttacag aaaactcatc tggtgggcat
    27001 cctgcgatac aagtagcctt accattgaca tctgttttga agagatgtgg atttgcccac
    27061 atatcacttg aatcttccgc tacgtagatt ggcatgtccc caacgatttc gatgtggttg
    27121 tcgttagcgt aagctttcaa tttcaaccat tgttggaaga agaagtattg agtcacacgg
    27181 tggtaaacca acttgtctgc caattgctca cgatagcttt caagtgctga agctttacga
    27241 gcacgagcat ctgcatctgg ccattcagtc caagcaagat tgtcaaaata ctctttgata
    27301 gccatatact cagcaaagag ctcaagccat gattggttgt cttgagcaaa tttctcaaaa
    27361 tctttaacat ctccgacttc aaagaaacgt ttcaccgctt tttctaaaag aggacgacgt
    27421 gcatagtaga ttttagcata gtcaacttca gacgcatcgc taccaaagtc aactccttca
    27481 aggtcacttg cttccaacaa accttgctcc accaagatat ctaaatcgat aaaatgagtg
    27541 tttcctgcga aggctgagaa agattggtaa ggagaatccc cgtaactagt tgctcctaat
    27601 ggaaggattt gccagtaacg ttgttttgta cggaccaaga aatcaacgaa gtcgtaagca
    27661 ctttgaccaa atgatccgat tccgtaagct cctggaagag aagagatgtg catcaacaca
    27721 ccactttgac gttttttcat aatagcacct cgtgtgttaa aataatggaa cgttgcgtat
    27781 tttgcagacg caaacgtttg cgttacttat aagtatactc cttttcaagc ataattgcaa
    27841 gcgtttttaa aaaacttttt tgattatttt taaggagact aactcatttt agcaaagata
    27901 acttaaaact atctaatcct aaggtttgac tctcacgaga cagtctacaa agtacaaaac
    27961 ctccttaggg agcttgaatt tatatgtaac aaagcacaaa cgtccataga aaatagatag
    28021 ggattagaac cagggaggta gcccctcctg gtttccctct ttagacagat tccatatatt
    28081 tttattaaaa atactgtatt cttatctatt tcatactttt cttctattaa aatgcaaaat
    28141 tatgctatca aatcaagctt aaaaattttt taaaattttt acaaaaaata cttgcaaccg
    28201 ttttctattt gtgctatact aagctcataa aggaaaacgt ttgcgtttcc ttatcaataa
    28261 aacttgctat tctttgggag gaatacacta tgtcatctaa atttatgaag agcactgcgg
    28321 tgcttggaac tgttacactt gctagcttgc ttttggtagc ttgcggaagc aaaactgctg
    28381 ataagcctgc tgattctggt tcatctgaag tcaaagaact cactgtatat gtagacgagg
    28441 gatataagag ctatattgaa gaggttgcta aagcttatga aaaagaagct ggagtaaaag
    28501 tcactcttaa aactggtgat gctctaggag gtcttgataa actttctctt gacaaccaat
    28561 ctggtaatgt ccctgatgtt atgatggctc catacgaccg tgtaggtagc cttggttctg
    28621 acggacaact ttcagaagtg aaattgagcg atggtgctaa aacagacgac acaactaaat
    28681 ctcttgtaac agctgctaat ggtaaagttt acggtgctcc tgccgttatc gagtcacttg
    28741 ttatgtacta caacaaagac ttggtgaaag atgctccaaa aacatttgct gacttggaaa
    28801 accttgctaa agatagcaaa tacgcattcg ctggtgaaga tggtaaaact actgccttcc
    28861 tagctgactg gacaaacttc tactatacat atggacttct tgccggtaac ggtgcttacg
    28921 tctttggcca aaacggtaaa gacgctaaag acatcggtct tgcaaacgac ggttctatcg
    28981 caggtatcaa ctacgctaaa tcttggtacg aaaaatggcc taaaggtatg caagatacag
    29041 aaggtgctgg aaacttaatc caaactcaat tccaagaagg taaaacagct gctatcatcg
    29101 acggaccttg gaaagctcaa gcctttaaag atgctaaagt aaactacgga gttgcaacta
    29161 tcccaactct tccaaatgga aaagaatatg ctgcattcgg tggtggtaaa gcttgggtca
    29221 ttcctcaagc cgttaagaac cttgaagctt ctcaaaaatt tgtagacttc cttgttgcaa
    29281 ctgaacaaca aaaagtatta tatgataaga ctaacgaaat cccagctaat actgaggctc
    29341 gttcatacgc tgaaggtaaa aacgatgagt tgacaacagc tgttatcaaa cagttcaaga
    29401 acactcaacc actgccaaac atctctcaaa tgtctgcagt ttgggatcca gcgaaaaata
    29461 tgctctttga tgctgtaagt ggtcaaaaag atgctaaaac agctgctaac gatgctgtaa
    29521 cattgatcaa agaaacaatc aaacaaaaat ttggtgaata aaaaatttgt tcaagggggg
    29581 tggaaatcaa atcccccttt gaatttatca atagagacac aaataattta gctttcttat
    29641 aaaaaagtag tatcctatga aaggagttaa tatggaaaag caacaaccta gtaaagcagc
    29701 cctgctgtct atcattcctg ggttaggaca gatttacaat aaacaaaaag ccaaaggttt
    29761 tatcttcctt ggtgtaacca tcgtatttgt cctttacttc ctagcacttg caacccctga
    29821 attgagcaac ctcatcactc ttggtgacaa accaggtcgt gataattccc tctttatgct
    29881 gattcgtggt gccttccatc taatctttgt aatcgtttat gtactctttt atttctcaaa
    29941 tatcaaagat gcacatacga ttgcaaaacg cattaacaat ggaattccag ttccacgcac
    30001 actcaaagac atgatcaaag ggatttatga aaatggcttc ccttacctct tgatcattcc
    30061 atcttatgtt gccatgacct tcgcgattat cttcccagtt atcgtaacct tgatgatcgc
    30121 ctttaccaac tacgacttcc aacacttgcc accaaacaag ttgttggact gggttggttt
    30181 gaccaacttt acaaacattt ggagcttgag taccttccgt tctgcctttg gttctgttct
    30241 ttcttggact atcatttggg ctttggcagc ttctacttta caaatcgtaa ttggtatctt
    30301 cacagctatc attgccaacc aaccatttat caaaggaaaa cgtatctttg gtgttatttt
    30361 ccttcttcct tgggctgtcc cagccttcat cactatcttg acattctcaa acatgtttaa
    30421 cgatagtgtc ggtgctatca acactcaagt attgccaatc ttggctaaat tccttccttt
    30481 ccttgatgga gctcttattc cttggaaaac agacccaact tggactaaga ttgccttgat
    30541 tatgatgcaa ggttggctcg gattcccata catctacgtt ctgaccttgg gtatcttgca
    30601 atctattcct aacgaccttt acgaagcagc ttatattgac ggtgccaacg cttggcaaaa
    30661 attccgcaac atcactttcc caatgatttt ggctgttgcg gcacctactt tgattagcca
    30721 atacaccttc aactttaaca acttctctat catgtacctc ttcaatggtg gaggacctgg
    30781 tagtgtcgga ggtggagctg gttcaaccga tatcttgatc tcatggatct accgtttgac
    30841 aacaggtaca tctcctcaat actcaatggc ggcagctgtt accttgatta tctctatcat
    30901 tgtcatctca atctctatga tcgcattcaa gaaactacac gcatttgata tggaggacgt
    30961 ctaagatgaa taactcaatt aaactcaaac gtagactgac tcaaagcctt acttaccttt
    31021 acctgattgg tctatcaatt gtaattatct atccactgtt gattaccatt atgtcagcct
    31081 ttaaagcagg taacgtctca gcctttaaac tagatactaa tatcgacctc aattttgata
    31141 actttaaagg cctcttcact gaaaccttgt acggtacttg gtacctcaac actttgatta
    31201 tcgcctta
//
LOCUS       DBEJZJ010000021        29876 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000021 DBEJZJ010000000
VERSION     DBEJZJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.21"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..4368
                     /locus_tag="ACL3R8_001279"
     CDS             <1..4368
                     /locus_tag="ACL3R8_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR1314151.1"
                     /translation="ALPEAVVSDKGEPEQVAPLPEYTRPQAGAVVEPAIQPELPEAVV
                     TDKGEPAVQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIV
                     EPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEASSTNGESER
                     PKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENF
                     KDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYT
                     SFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGKLIGENNGKYYAIY
                     NLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERG
                     IGGLVSKVDNSRISNSSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIEKSIASIDIA
                     SNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSK
                     SGKLSYVLSDVNVTNGNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQ
                     RGTVLDADKVKEKKAELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSREQVYKNIEKL
                     LPFYNRETIVKYGNLVDESSELFTKELLSVVPMKNNEVITDINKNKQEINKLLLHFEG
                     NKSQVLNIAYKNDFSKVAEYSIEYQGLLYTPNTLLHDYSNIVDNVLTDLNSVQYDSNA
                     IKKILDISDKVKNTELYLDEQFVKTKANIKDTLSKLLSADAAIAENSNSIIDNYVIQK
                     IKQNKEALLLGLTYLERWYNFKYGETKAKDLVMYHLDFFGKSNSSALDNVIQLGKSGF
                     NNLLAKNNVITYNVLLSKNYGTESLFKALEGYRKVFLPTTSNNEWFKAQTKAYIVEEK
                     SSIPEVSKKQSEQGTKYSIGIYDRLTSPSWKYQSMVLPLLTLPEEKTVFMIANISTIG
                     FGAYDRYRSKVHPKGDNLNKFVEDNVREAAKRFRDHYDYWYKILEPENREKLYRSLLV
                     YDAFKFGRDNTEDKVTYQADFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAY
                     RMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITIN
                     SVLKYDDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDLIYTLEILEGRAVAKLDYNA
                     KNDLLRKIENKYKQDPDGNSVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQ
                     EYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYE
                     KDAKAAGSKIKSYGKEVGLVTDKLVLEKVFNNRYSSWVEFKKAMYNERIAKFNNLISV
                     SFNNPNVSWGRTNRITITSIANLQNMINTAVNEDAEDFRAQLYPDTNSRVLKLKKAIY
                     KAYLDQTNDFRRSIFENKK"
     gene            4412..9649
                     /gene="zmpD"
                     /locus_tag="ACL3R8_001280"
     CDS             4412..9649
                     /gene="zmpD"
                     /locus_tag="ACL3R8_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpD"
                     /protein_id="HGR1314152.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVT
                     SYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNY
                     ELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRG
                     QGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMY
                     LKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKP
                     HPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEG
                     KHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVT
                     GNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYV
                     DANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLS
                     HHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKE
                     HHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDL
                     AYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMV
                     HYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASV
                     QLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADH
                     QLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSV
                     DLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDW
                     FIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYN
                     TMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRV
                     PTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNP
                     NNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTP
                     SSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHV
                     EADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSS
                     INDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKH
                     NAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKY
                     WYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVF
                     KALLKNTDGFFNPLFKKDI"
     gene            9816..11162
                     /locus_tag="ACL3R8_001281"
     CDS             9816..11162
                     /locus_tag="ACL3R8_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR1314153.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFRLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSCLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKMDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            11577..12428
                     /gene="ylqF"
                     /locus_tag="ACL3R8_001282"
     CDS             11577..12428
                     /gene="ylqF"
                     /locus_tag="ACL3R8_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR1314154.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            12415..13194
                     /locus_tag="ACL3R8_001283"
     CDS             12415..13194
                     /locus_tag="ACL3R8_001283"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR1314155.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            13210..14760
                     /locus_tag="ACL3R8_001284"
     CDS             13210..14760
                     /locus_tag="ACL3R8_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR1314156.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            15344..16414
                     /gene="xerS"
                     /locus_tag="ACL3R8_001285"
     CDS             15344..16414
                     /gene="xerS"
                     /locus_tag="ACL3R8_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR1314157.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(16481..17470)
                     /locus_tag="ACL3R8_001286"
     CDS             complement(16481..17470)
                     /locus_tag="ACL3R8_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR1314158.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(17534..19237)
                     /gene="lpdA"
                     /locus_tag="ACL3R8_001287"
     CDS             complement(17534..19237)
                     /gene="lpdA"
                     /locus_tag="ACL3R8_001287"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR1314159.1"
                     /translation="MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            complement(19283..20326)
                     /locus_tag="ACL3R8_001288"
     CDS             complement(19283..20326)
                     /locus_tag="ACL3R8_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR1314160.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGIQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            complement(20544..21536)
                     /locus_tag="ACL3R8_001289"
     CDS             complement(20544..21536)
                     /locus_tag="ACL3R8_001289"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR1314161.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            complement(21552..22520)
                     /locus_tag="ACL3R8_001290"
     CDS             complement(21552..22520)
                     /locus_tag="ACL3R8_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR1314162.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            complement(22674..24035)
                     /gene="pdrM"
                     /locus_tag="ACL3R8_001291"
     CDS             complement(22674..24035)
                     /gene="pdrM"
                     /locus_tag="ACL3R8_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR1314163.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(24046..24306)
                     /locus_tag="ACL3R8_001292"
     CDS             complement(24046..24306)
                     /locus_tag="ACL3R8_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314164.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(24320..25588)
                     /locus_tag="ACL3R8_001293"
     CDS             complement(24320..25588)
                     /locus_tag="ACL3R8_001293"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR1314165.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(25601..26065)
                     /locus_tag="ACL3R8_001294"
     CDS             complement(25601..26065)
                     /locus_tag="ACL3R8_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR1314166.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPELDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(26075..26728)
                     /locus_tag="ACL3R8_001295"
     CDS             complement(26075..26728)
                     /locus_tag="ACL3R8_001295"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR1314167.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            complement(26864..27466)
                     /locus_tag="ACL3R8_001296"
     CDS             complement(26864..27466)
                     /locus_tag="ACL3R8_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314168.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            complement(27524..28237)
                     /locus_tag="ACL3R8_001297"
     CDS             complement(27524..28237)
                     /locus_tag="ACL3R8_001297"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR1314169.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTVDIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(28696..29076)
                     /gene="dhaM"
                     /locus_tag="ACL3R8_001298"
     CDS             complement(28696..29076)
                     /gene="dhaM"
                     /locus_tag="ACL3R8_001298"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR1314170.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(29076..29150)
                     /locus_tag="ACL3R8_001299"
                     /pseudo
     CDS             complement(29076..29150)
                     /locus_tag="ACL3R8_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            complement(29498..>29876)
                     /locus_tag="ACL3R8_001300"
     CDS             complement(29498..>29876)
                     /locus_tag="ACL3R8_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR1314171.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
BASE COUNT         9608 a         5682 c         5687 g         8899 t
ORIGIN      
        1 gcgttacccg aagcggttgt aagtgataaa ggtgaaccag agcaggtagc cccattgcca
       61 gaatatacaa gaccacaagc aggtgcagta gttgaacctg caatccaacc agagttacca
      121 gaagctgttg taactgacaa aggagaacca gcagtccaac cagagctacc ggaagcggtt
      181 gtaactgaca aaggtgagac tgaggttcaa ccagagtcgc cagatactgt ggtaagtgat
      241 aaaggtgaac ctaaacaggt agcaccgctt ccagaatata caggaccaca agccagcgct
      301 attgttgaac cagagcaagt agcaccacta ccagaataca caggggtaca agccggatcg
      361 atagtcgagc cagagaaagt agaagcaccg aaagaatata ctggtaaaat cgaacaacct
      421 agtgcagaag atactaaacc tgaaaatgag gcaagctcta caaatgggga atcggaacgt
      481 cctaaagata aaattaaaga agaaaaacaa gtcgacaaga aactagaact tagaaatgtt
      541 tcaaacgtgg aattatatac ggtagaaaat aataaatatc gacatattac ggctgtagat
      601 ggtgctttag atagttcatt gaagtatttc atgaaggtaa aatcagaaaa ttttaaagat
      661 ataatgttgc ctgttactaa aattgaaagt acaacaaaaa acaataaaga agtatacaaa
      721 attgtggctc atgcagaaaa tctaattcaa cacgaaaaca atgttatttc gaatgactat
      781 acatattatt taccaaaaac tcagcaaagt gaaactggcg tctatacatc atttaaaaat
      841 ttagttgatg caatgaatag tgaccctaat ggaacattcc atttaggtgc aactatggat
      901 gctcgtgaag ttgaacttcc ggatgatcaa gaaagttatg taaaaaatga attttacgga
      961 aaattaatag gtgaaaataa tggtaagtat tatgctattt ataacttgaa aaaaccttta
     1021 tttaaaactc taaacaccgc tactattcag aatctttcaa taaaagaagc gaatgtttct
     1081 tctaaagaag atgctgctac aatatcgaaa gaagcaaaat acaatactct tatagataat
     1141 gttcattctg atggtattat agctggtgaa cgtggaattg gtggattggt ttcaaaagta
     1201 gataactcga gaatttctaa tagtagtttt acaggcagaa taactaacac atatgataca
     1261 actgtagggt atgaaattgg tggtttagta ggtaaacttt ctggttcgct tgcttctata
     1321 gagaaatcaa tagcatcgat tgacatagcc tctaatgcaa aatcaggaga tcaaattgtt
     1381 ggtggtatag ccggagttgt tgagaaaagt gcgacaatta agtatagcta tgttgaagga
     1441 aatgttaaca atgtgcgaca ctttggtaaa gttgggggag ttgcaggtaa tctttgggat
     1501 agagattcac aagatgtaag taaatcaggt aaactatcat atgttttaag tgatgttaat
     1561 gtaacaaatg gtaatgctat atcgggtgat aattttgata atatgaaaga agatcatgct
     1621 tatagtagta aaggcaataa agtagtaaat gtagtccaag tagatgatga acttgtgact
     1681 aaagattcag atgtacaaag aggtacggta ttagatgctg ataaagtaaa agagaaaaag
     1741 gcagaattgg tttccaaaca cagcactaaa gtagaagatt ttgatttcac ttcaagatac
     1801 actactattt acaatgaagt aacaggttat caaaagtcga gagaacaagt atataaaaat
     1861 attgaaaaac tattaccgtt ctataatcga gagacaattg ttaaatatgg taatttagta
     1921 gatgaaagca gcgagctatt tactaaagaa cttctatcag ttgttcctat gaagaataat
     1981 gaagtaataa ctgatattaa taaaaataaa caagaaataa acaaattgtt attacatttt
     2041 gaaggtaata aatcacaagt attaaatatt gcatataaga atgatttctc taaagttgct
     2101 gagtatagta tagagtatca aggattatta tatactccca atactctatt gcatgactac
     2161 agtaatattg tagataatgt tttaactgac ttgaattctg tacaatatga ttcaaatgca
     2221 attaagaaaa tattagatat ctcagataaa gttaaaaata cggaattata cttagatgag
     2281 caatttgtta aaacaaaagc aaatataaaa gatactttat caaaacttct gtcagcggat
     2341 gcagcaatcg ctgagaatag taattcgata attgataatt atgttattca gaaaatcaaa
     2401 cagaataaag aagctttatt gttaggatta acatacttag agcgttggta caattttaaa
     2461 tatggtgaaa cgaaagcaaa agatttagtt atgtatcact tggatttctt cggtaaatct
     2521 aatagttctg cattagataa tgttattcaa ttaggtaaat ctggatttaa caatttacta
     2581 gcaaaaaata atgtaattac ttacaatgta ttattatcta aaaattatgg aactgaaagt
     2641 ttatttaaag cattagaagg atatagaaaa gtattcttac caacaacttc taacaatgag
     2701 tggtttaaag ctcaaactaa agcatatatt gttgaagaaa aatcttctat tccagaagta
     2761 agtaaaaaac aatcagaaca aggaactaag tattctatag gaatttatga tagattaact
     2821 agtccgtcat ggaaatatca aagtatggtc ttaccactat taactttacc tgaagaaaaa
     2881 acagtattta tgatagcgaa tatttcaaca ataggatttg gtgcttatga tagatataga
     2941 agtaaagtcc atcctaaagg agataactta aataaatttg tagaagacaa tgtaagagaa
     3001 gctgcaaaaa gatttagaga tcattatgat tattggtata aaatattaga gcctgagaat
     3061 agagagaaac tttatagaag tttattagta tacgatgcat ttaaatttgg tcgagataat
     3121 actgaagata aagtaactta tcaagctgat tttgaaactg atcatccagc tataaaatac
     3181 ttctttggac ctgcggggaa taatgttgtt cataatggac acggagcata tgctaccgga
     3241 gatgcattct attatatggc atatcgtatg ttggataaag atggagctgt aacatatact
     3301 catgaaatga cacataactc tgatagagaa atttatcttg gaggatatgg aagaagaagc
     3361 ggattagggc ctgagtttta tgctaagggc ttattacaag cacctgacca cccatatgat
     3421 ccaacaataa caattaactc tgtgttgaaa tatgatgatt cagaaaattc aacaagactt
     3481 caagtagctg atccaactca acgatttaat agtgcagaag acctacataa ttatatgcat
     3541 aatatgtttg atttaatata tactcttgaa atattagaag gtcgtgctgt agctaaatta
     3601 gattataatg cgaaaaatga tttattaaga aaaattgaga ataaatataa gcaagatcca
     3661 gatggtaatt ctgtttatgc gacaaatgtt gttcgcagat taacgatgga tgaagttaat
     3721 aaattaaatt cttttgatag tttaattgaa aatgatatta ttactagcag agggtacaaa
     3781 gaccaagaat ataagagaaa tggttattat acaattgatt tattttcacc gatttattca
     3841 gctcttagtg gagagaaagg gactcctggt gatttaatgg gacgtcgtat agcattcgaa
     3901 ttattagctg caaaaggata taaagagggc atggtacctt atatctcaaa tcaatatgaa
     3961 aaagatgcaa aagctgcggg aagtaagatt aaatcttatg gtaaagaagt aggtttagtt
     4021 acagataaat tagtacttga aaaggtattt aataatcgtt actcatcttg ggtagaattt
     4081 aaaaaagcaa tgtataatga gcgaatagct aaatttaata atctaataag tgttagcttt
     4141 aataatccaa atgtaagttg gggaagaact aatagaataa caataactag catagccaac
     4201 cttcaaaata tgataaatac ggctgtcaat gaagatgctg aagattttag agcacaatta
     4261 taccctgata caaatagtag agttcttaaa ctgaaaaaag caatatataa agcctatctt
     4321 gaccaaacaa atgattttag aagatcaatt tttgagaata aaaaatagtg tttactatta
     4381 ggaaataaaa agtgaatgtg gaggattaga attgtcatta ttaaaaaaag ataaattttc
     4441 cattaggaaa ataaagggta ttgttggttc gatattcttg gggagttttt tatttgcact
     4501 gtcagttgtt ggtgtatcga cttatcatta cttagattat agtactttga cacaaactga
     4561 acgtgatcaa ctcaaacaag gtagacctga tgaatcaaaa gagtcatatg ctttggttta
     4621 tgaaaaagac gcattaccaa acacaggaag ttctcaatct attatgactg tattgggttt
     4681 gttagctatc gggagtctta ttgtgattat cacaaaagat aaaaagagga aaaaaatagc
     4741 tacatttttg attgtagggg cgacaggttt agttacacta tcaactgctt cagcacttaa
     4801 tttgaatgct aacatccatg agtctggacg tgatggtgtg ttgcaaattt ctggttacag
     4861 atatgttggt tacttggagc ttgatgatag aactgtttcg tcggtttctc cagcatcaac
     4921 tgtttctcca gttgagcaac ccaaagttgt gaccgacaaa ggcgaaccag aagttcagcc
     4981 agcgttacca gaagcagttg taactgaaaa aggggaacca gaagtacaac cagccttacc
     5041 cgaagcagtt gtaactgaaa aaggggaacc agaagttcat gagaagcctg actatacgca
     5101 accaataggt gcaaaccttg ttgagcctga agttcatgag aaactagcat acactgaacc
     5161 tgtaggtaca acaggagtag atgaaaatgg aaacttgatt gagccacctg ttaacgatat
     5221 tccagagtat actgaaccaa tatctacagt ttcagaagtt gcatcagaaa gagaagagtt
     5281 gccttcttta cataccgata ttcgtacaga gactattcct aaaaccacta tagaagaatc
     5341 tgatcctagc aaatttatag gcgataattc tgttaaacaa gttagtgagg atggcgaacg
     5401 tcaaattgtt actagctatg aagagttaca tggcaaaaaa atcagcgagt cagttgaaac
     5461 agtaacaatt ttgaaagaaa tgaagcctga aattattgta aaaggtacaa aagaaaaaac
     5521 ggctcctgtt ttaaccttga ccaaagtaac agaagatgct atgaatcgtt ctgccaactt
     5581 aaattatgag cttgataata aagataatgc tgaaatatca agtattgtag ctgaaattaa
     5641 agatggtgat acagtagtta aaagggttga tttatctaaa gaaaaattaa ctgacgctgt
     5701 acaaaatttg gattggttta aagattataa gattgcaaca acaatgattt atgatcgtgg
     5761 tcaaggttct gaaacgtcta aactggatga aagacctctg cgtttggagt tgaaaaaggt
     5821 cgaaattaaa aatatcgcat ctactaattt agtgaaggta aatgatgatg gtactgaaac
     5881 acctagtgat tttatgaatg aaaaaccttc agaagaagat gttaaaaaaa tgtacttaaa
     5941 aatcactagt cgcgataata aggtaactcg tttaactgta gactctattg aagaagtgac
     6001 tgaagaaggt caaaaacttt acaaaataac tgctgaagca caagatttga ttcaacacac
     6061 agacccaacg aaggttcgta ataagtatgt ttattatata gaaaaacccc atcctaaaga
     6121 agataatgtc tactataact ttaaagattt agtagatgct atgaatactg ataaaaatgg
     6181 tacatttaaa cttggtgcag atttgaatgc cactggtgtt ccaacaccta agaaatggta
     6241 tgttgacggc gactttagag gtacattgaa gagtgtagag gggaaacatt atactatcca
     6301 caacacggag cgtccgttat tccagaatat tattggtggt acagtaacca aagtaaatct
     6361 gggaaatgta aatatcaata tgccatgggc agaccgcatc gcaccgattg ctgacactat
     6421 taaaggtggc gctaaaattg aagatgtcaa agtgactggt aacgtattag gtagaaactg
     6481 ggtatctgga tttattgata agattgacaa ccaaggtaca ctcagaaatg tagcctttat
     6541 cggaaatgtg acatctgtag gtgatggtgg tcaattcttg accggtatcg ttggtgagaa
     6601 ctggaaagga ctagtcgaac gtgcgtatgt tgacgcaaat cttattggca agaaagccaa
     6661 ggctgctggt attgcttatt ggacacaaaa cagtggtgac aatcataaag ttggtgtcga
     6721 aggtgcagtc aagaaaggaa ttgtgaaggg taccattcag gtagaaagtc ctgttgaagt
     6781 cggcggtgct gttggacgtt tgagtcatca tggttatatc ggggaagtcg tatctatgat
     6841 gaaagttaag aagggtgaaa ttttttatgg ttctagtgat atgaatgatg acccatattg
     6901 ggtggcgaat aatgtacgag gaaattatgt cgttaatggt gtgagtgaag gtacgatatc
     6961 ttatgctcgt gctaaagaac accatcgtat caaaccaatt tcacagtcag aagcagatac
     7021 taaaattatg atgttaggta ttacagcaca agattttgct atcaacgaac ctgtggtcaa
     7081 tcgcttaaac cgtttaacca gaaaagaaga tgaatataag tcaacccaag actataaagt
     7141 agatcgagat ctggcttatc gtaatattga gaaacttcaa ccattttata acaaagaatg
     7201 gattgtcaac caaggtaaca aacttgcaga agattcaaac ttagctaaga aagaagtcct
     7261 ttctgttacg ggtatgaagg atggacagtt tgtaactgac ttatcagata ttgataagat
     7321 tatggttcac tatgctgatg gtactaaaga agaaatggac gtcactaaga atgctgattc
     7381 taaagtgaaa caagttcgtg aatataccat cgctggacaa aacgttgttt atacaccaaa
     7441 tatggttgag aaagaccgta accaattgat tcaagatatc aaagataagt tggcgtcagt
     7501 tcaattgatt tctcctgaag tacgtgcttt gatggatgca cgtaagaaac cagaagaaaa
     7561 tactgatgaa cgtaagaatg gttatattaa agacctttac ttagaagaaa gctttgctga
     7621 aacgaaagct aatcttgata aattggttaa atccttagtt gaaaatgcag atcatcaatt
     7681 aaatagtgac gaaacggcta tgaaagcact tgttaagaag gtggatgaaa ataaagctaa
     7741 aatcatgatg gctctgactt atctcaatcg ttactatgat atcaagtatg gggatatgac
     7801 tatcaagaac ttgatgatgt ttaaacctga tttctatggt aaatcagttg accttcttga
     7861 tttcttgatt cgaattggat caagtgagag aaatatcaaa ggtgacagaa ctttggatgc
     7921 ttatcgtgat atgattggtg gaactattgg taagtctgaa ttacatggat tcttagatta
     7981 caatatgcgt ctcttcacta acgatactga tttaaatgat tggttcatcc atgcagctaa
     8041 gaatgtatat gtatcagaac ctcaaacaac gaacccagat tttgttaata aacgacatcg
     8101 tgcatttgat ggtttgaaca acggtgttca taatcgtatg attctacctc tattaactct
     8161 taagaatgca catatgttct tgatttcaac ttacaataca atggcttata gttcttttga
     8221 gaaatatggt aagtatacag aagaagctag aaatgaattc aaaaaagaaa ttgataaggt
     8281 tgcacatgct caacaaacat acttagactt ctggtcacgt ttagcattgc caagcgtacg
     8341 tgaccaatta ctcaagagtg agaatagggt accaactcct gtgtgggata accaaaacta
     8401 tagtggtatt aaaggaataa accgtatggg ttatgatgag aagaaagtac caattgcgcc
     8461 aattcgtgag ttatatggtc caacttggaa attccataat accaactgga atatgggagc
     8521 tatggcatct attttcccaa atcctaataa caatgaccaa gtttatttca tgggaacaaa
     8581 tatgattagt ccgtttggta tttcagcctt tactcatgaa actacacacg ttaatgatag
     8641 aatgctttac ttcggtggtc atagacaccg tcaaggtaca gacgtcgaag cctatgctca
     8701 aggtatgcta caaactccgt caagtattgg tcaccaaggt gaatatggtg ctttaggttt
     8761 gaacatggct tatcatcgtg aaaatgatgg tgaccaatgg tataactatg accctgataa
     8821 gcttcaaact cgtgaagata tcgatcgata tatgaaaaac tataatgaag cactgatgat
     8881 gctagatcat gtagaagcag acgccgtact tccacaattg aatggtgata atagcaagtg
     8941 gttcaagaaa attgatagag aaatgcgcag aaatcttggg gatggtttga ataacttagt
     9001 agcaccgcac caatgggaca acgttcgtga cttaaatcaa gaagagagtt ctaagaaatt
     9061 atcaagtatt aacgatttga ttgataataa tttcatgacc aaacacggaa atccaggtaa
     9121 cggacgttat agaccagagg attttagacc aaactcagct tacgtaaatg tcaatatgat
     9181 ggcaggaatt tacggtggga atacgagtca aggtgctcct ggttcattat cgttcaaaca
     9241 taatgccttc cgtatgtggg gttattatgg atatgacaaa ggtttcacta gttatgtatc
     9301 tagcaaatat caaggtgaag ctgataaaca aaaccagggt agattaggtg atgatttcat
     9361 tatcaaaaaa gtttcaaaca accaattctc aaatcttgaa gattggaaga aatattggta
     9421 tcatgatgtg aaatccagag ctgaaaaagg attcacagag attacaattg atggacaaac
     9481 cattcacaac tataatgaac tgaaagactt attcgacaaa gctgtcacag aagacctcaa
     9541 gaaagctgga aactactcaa atactgagaa tttgaaatcc aaagtcttca aagctcttct
     9601 taaaaacaca gacggtttct ttaatccatt gttcaaaaaa gacatttaaa ccccaattat
     9661 tcaccccaaa tctaaaaacc atccagaatc cttgccttag cttagatcct ggatggtttc
     9721 tttttcaccc aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag
     9781 tgtagaaaaa aaacacaaaa agaaaggaaa ctcacatgaa cagtttacca aatcatcact
     9841 tccaaaacaa gtctttttac caactatctt tcgatggagg tcatttaacc cagtatggtg
     9901 gtcttatctt ttttcaggaa cttttttccc agttgaaact aaaagagcgg atttctaagt
     9961 atttagtaac gaatgaccaa cgccgctact gtcgttattc ggattcagat atccttgtcc
    10021 agttcctctt tcgactgtta acaggctatg gaacggacta tgcttgtaaa gaattgtcag
    10081 ctgatgccta ctttccaaaa ttgttggaag gagggcagct tgcttcacag ccaaccttat
    10141 cccgttttct ttccagaact gacgaggaaa cagtccatag tttgcgatgc ctcaaccttg
    10201 aattggtcga attcttttta cagtttcacc agctaaacca actcattgta gatatcgatt
    10261 ctacccattt cacaacttat ggcaagcaag aaggtgttgc ttataacgcc cactatcgtg
    10321 ctcatggcta tcatcctctt tacgctttcg aggggaagac aggttattgt ttcaatgccc
    10381 agcttcgtcc tggtaatcgt tattgttctg aagaggcaga cagctttatc acacctgttt
    10441 tagaacggtt taatcaactt ctctttcgaa tggatagtgg ctttgcgacc ccaaaattat
    10501 acgatttaat tgaaaaaaca gggcaatact acctcataaa actcaagaaa aatactgttc
    10561 tgagctgtct tggagacctt tccctccctt gcccacagga tgaggactta accatcttgc
    10621 cccactccgc ctactcagaa actctctatc aagcaggatc ttggtcgcac aagcgtcgtg
    10681 tctgccagtt ctctgaacga aaagaaggaa acttgttcta cgatgttatt tctctcgtta
    10741 caaatatgac gagtggaaca agccaagacc agtttcagct ttatcgtgga cgtggtcaag
    10801 ccgagaattt catcaaggag atgaaggagg gattttttgg cgataaaatg gatagttcaa
    10861 ccttaatcaa aaacgaagtt cgtatgatga tgagctgtat cgcctacaat ctctatcttt
    10921 ttctcaaaca tctagctgga ggtgacttcc aaactttaac aatcaaacgc ttccgccatc
    10981 tttttcttca cgtggtagga aaatgtgttc gaacaggacg caagcagctc ctcaaattgt
    11041 ctagtctcta tgcctattcc gaattgtttt cagcacttta ttctaggatt agaaaagtca
    11101 acctgaatct tcctgttcct tatgaaccac ctagaagaaa agcgtcgtta atgatgcatt
    11161 aaagaacagt cgagatgaaa aaatcgtgtg acgcaccaag ggaggagtct gcccttttga
    11221 ggaaatctag cgaggaaaaa cgatactgga acagcagaaa gtaaaactga cctcatgagg
    11281 acatgaggtc aggggttttg taagttacat ctagttgaga gaggtatgaa tgatttgggt
    11341 taaatgttta aaacataaag aggacagttt tttgctccct ctgaaaagtc atcatttgat
    11401 ggcttttttc tatatagggt aaaaggctat catcggacaa aataaagaag gcatgatata
    11461 atataaagta gatttttatg tcataaaaca agaactgttt ggacatcatt catttttaga
    11521 ttgagatctc ttagttctag attaacagct tcagagctac gaaaggaaaa aactcaatgg
    11581 ctactattca atggtttcct ggtcacatgt ctaaagctcg tcgacaggtg caggagaatt
    11641 taaaatttgt tgattttgtg acgattttag tagatgcacg cttgcctcta tctagtcaaa
    11701 atcctatgtt gaccaagatt gttggtgata aaccaaaact cttgatttta aacaaggccg
    11761 acttggctga tccagcaatg accaaggaat ggcgtcagta ttttgaatca caaggaatcc
    11821 agacgctagc tatcaactcc aaagagcaag tgactgtaaa agttgtaaca gatgcggcca
    11881 agaagctcat ggctgataag attgctcgcc agaaagaacg tgggattcag attgaaacct
    11941 tgcgtaccat gattatcggg attccaaacg ctggtaaatc aactctgatg aaccgtttgg
    12001 ctggtaaaaa gattgctgtt gttggaaaca agccaggggt cacaaaaggt caacaatggc
    12061 ttaaaaccaa taaagacctg gaaatcttgg atacaccggg gattctctgg cctaagtttg
    12121 aggatgaaac tgttgcactt aagttggcat tgactggagc tatcaaagac cagttgcttc
    12181 ctatggatga ggttaccatt tttggtatca attatttcaa agaacattat ccagaaaagc
    12241 tggctgaacg cttcaaacaa atgaaaattg aagaagaacc gtctgtgatt attatggata
    12301 tgacccgcgc cctcggtttc cgtgatgact atgaccgttt ttacagtctc ttcgtgaagg
    12361 aagtccgtga tggcaaactc ggtaactata ccttagatac attggaagac ctcgatggca
    12421 acgattaaag aaatcaaaga actccttgtg acagtcaagg agttagaaag ccctattttt
    12481 ttagagcttg aaaaggataa tcgctcagga gttcaaaagg aaatcagcaa gcgtaaaaga
    12541 gccatccaag ctgaattaga tgaaaatttg cgcttggaat ccatgctttc ttatgaaaaa
    12601 gaactttata agcaaggatt gaccttaatt gcaggtattg atgaggttgg tcgtggtcct
    12661 cttgctggtc ctgtagtcgc tgcggccgtt attttaccta aaaattgtaa gattaaaggt
    12721 ctcaacgaca gcaagaaaat tcctaaaaag aaacatctgg agattttcca agccgttcaa
    12781 gaccaagcct tgtcgattgg aattggtatc atagataatc aggtcatcga ccaagtcaac
    12841 atctatgaag caaccaaact agccatgcaa gaagcaatct cccagctcag ccctcaacca
    12901 gagcaccttt tgattgatgc catgaaactg gacttgccca tttcacaaac ctccattatc
    12961 aaaggagatg ccaactccct ctctatcgca gcagcatcta tagtagccaa ggtaacacgt
    13021 gatgaattga tgaaagaata cgatcagcag ttccctggct atgatttcgc tactaatgca
    13081 ggatatggca cagctaaaca tctggaaggc ctcacaaaac taggagttac cccaattcac
    13141 cgaaccagct ttgaacccgt taaatcactg gttttaggta aaaaagaaag ttaattgaaa
    13201 ggaaatacca tggaggaaca gtcggaaata gtccgttcta agaaagaatt cgcctttgca
    13261 tccagcacta tactatccca agttggtcga ggaatcattg tcggcctcat cgttggaatt
    13321 atcgtcggat cctttcgttt cttaattgaa aagggcttcc acatgataca aggagtttat
    13381 caagatcaag ggtacttagt gcgcaatctt tttgtactgg ttttgtttta tatactcatc
    13441 tgttggctca gtgccaaact aacacggtca gaaaaagata ttaaaggctc aggaattcct
    13501 caagtcgaag ccgaactgaa aggcctcatg tccctcaact ggtggggcat tctttggaaa
    13561 aaatatgtgc taggtattct cgctattgcc agtggactca tgctgggtcg agagggaccc
    13621 agtattcaac ttggagcagt tggtggtaaa ggaattgcca agtggctcaa atccagtcca
    13681 gtagaggaac gttccttgat tgccagtgga gctgcagcag gtttagccgc agcctttaat
    13741 gctcctattg cagcacttct ctttgttgta gaagaagtct atcaccattt ttcgcgcttt
    13801 ttctgggtct caactctagc agccagcatc gtagcaaact ttgtgtctct actcatgttc
    13861 ggtttgacac cagtattgga tatgccagat aacattcctc ccatgaccct agatcagtat
    13921 tggatatatc tcgtcatggg aattttcctt ggattttcag gctttctcta tgagaaagct
    13981 gtattaaacg ttggaagagt ttatgacttg attggtcaaa aaatccattt ggatagagct
    14041 tattatccca tcttggcttt tatccttatc ataccagtcg gaatcttctt acctcaaatc
    14101 attggtggcg gaaatcagct tgtcctttct ttaactgaac aaaattttag tttccaagtt
    14161 ttattagctt actttttgat ccgctttatt tggagtatga ttagctatgg aagtggactg
    14221 ccaggaggaa ttttcctccc cattttagct cttggttctt tgcttggtgc cttaattggt
    14281 gttatctgtg tcaatcttag acttgtcagt caagagcaat tccctatatt tgtcattcta
    14341 ggaatgagtg gctattttgg agccatatca aaagctccct taaccgctat gatcctcgta
    14401 actgagatgg taggagatat tcgcaacctc atgccacttg gtcttgtcac tcttgtttct
    14461 tatattatca tggatttgct caaaggtacg ccagtctatg aagccatgct ggaaaaaatg
    14521 cttccagaag aagtatctag cgaaggagaa gttacactta tcgaaatacc agtttctgat
    14581 aaaattgctg ggaaacaagt tcatgaactc aacttaccac acaacgtcct catcacaact
    14641 caagtccata atggcaagag ccaaacagtt aacggctcaa ccagaatgta tctgggtgat
    14701 atgattcacc tggttattcc aaaaagtgaa attggaaaag tcaaagattt gttgttgtag
    14761 tacaatcatt tacataattt atattatgta aatgattggc ttgatttatt tagaaaaccg
    14821 attctcagaa atgagatcgg ttatttttta ctgatgagga attttacata taaataattg
    14881 aactttatta aaaataagac tataattaag ttagaaatga taaagtataa agctagaaag
    14941 gagtttactg tatcaaatct gtacagtaag attaaaatca tgaaaaagaa aacaatagca
    15001 attatatagt gaaatgaaat agaaatagga taaaacaatc aggacaatca aatcaatttc
    15061 tagcaatgtt ttagaagttc agatgtacta ttctagtttc aatctattat acaatgtgtt
    15121 ttgtatctca tagctcctta tatagctctt cagttatgta gtattaacag aagtttagtg
    15181 ggtgagattt ttattatttt ccttattctg ttttgtttgt aggtctaagt ctttttatca
    15241 ctttgaaaaa ctcctataac atctttcaga aaaactataa ttttcttgaa aaatatacaa
    15301 gtctatgcta tactactagt atacttactt atggagaaaa tacatgaaac gtgagatttt
    15361 actggaacga atcgacaaac taaaacaact catgccctgg tatgttctgg aatactacca
    15421 atctaagctg gctgtgccct acagttttac aaccctgtac gaatacctta aggaatatga
    15481 ccgatttttc agctgggttt tggagtctgg tatttcaaac gctgataaaa tatccgatat
    15541 tcctttatca gttttggaaa atatgtctaa gaaagacatg gaatccttta tcctttatct
    15601 acgtgaacgt cccttgctga atgctaatac aacaaaacaa ggtgtttcac agacaactat
    15661 caatcgaacc ttatcagcac tttctagtct ttacaagtat ctaaccgagg aggttgaaaa
    15721 cgatcagggg gaaccttatt tctatcgtaa tgtaatgaaa aaagtttcaa ccaagaaaaa
    15781 gaaagaaacc cttgctgcca gagctgaaaa tatcaagcaa aaactctttc taggtgatga
    15841 aacagaaggt tttctaactt atatcgatca agagcaccca caacagcttt caaatcgagc
    15901 tctctcatca ttcaacaaaa ataaagaacg agatttagcc attattgccc ttctcttggc
    15961 atctggtgtt cgcttatctg aagctgttaa tctagatcta agagatctca atctaaaaat
    16021 gatggttatt gatgttactc gaaaaggtgg caaacgtgac tcagtcaatg tcgctgcttt
    16081 tgctaaacct tatttagaga attatctggc cattcggaat caacgctata aaacggaaaa
    16141 aacagataca gccctttttt taactctcta cagaggtgtt cctaatcgta tcgatgcttc
    16201 tagcgttgag aaaatggttg ctaaatactc agaggatttt aaagtgcgtg taacacccca
    16261 taaactgcgc catacgctag caactaggct ctatgatacg actaaatcac aagttttagt
    16321 cagtcaccaa ctaggacatg ccagcacaca agtcactgac ctctataccc atattgttaa
    16381 tgatgaacaa aagaatgctc tagatagttt atgattttac gtattttaaa ttatgtaaat
    16441 aaatatcaaa aaaagaagtt ggccaacttc tttttttgat ttatccaact accgcttcag
    16501 cgatttcttc acggctaata ccagcgaagt agcgtgtgat atcaatggtt tttagcgcct
    16561 taagaacatc ttcgcgttcg tatttcaccc cacgaaggac atcttctact gcagcaacgt
    16621 cttcaatacc aaagaagtca ccataaatct tgatgtcttg gatttttgat tcagtaacgt
    16681 tagcaaagac ttcaacctta ccactagtga atttggttcc acgacggacg ttaaattcag
    16741 gtgatttacc atagttccag tcccaagttc caaacttagt atccttgatg tgattgattt
    16801 cggccaattc ttcttctgaa aagacgtatt cagtcatctc tgggtactct tttttcatgt
    16861 attccaggag taaatcacgg aatttttcga ctgtgatttt ttttggtaat tcattgataa
    16921 tattggttac acgggcacgg acggatttca caccttttga ttcaaattta tcttttgaaa
    16981 ccttaagggc atttgcgagg actgacaaat caacgtcaaa gagcaagcaa ccgtggtgca
    17041 tgatacggcc gttgatatag gcttgggcat tgccacagaa cttcttacca tcaatctcaa
    17101 ggtcattacg acctgtgaac tcagctttaa ccccaagttg agccagggta ttgataaccg
    17161 gagttgagaa gctcttgaag tcaaatgcct tattttcatc ttctttggag atgatcgtgt
    17221 agttgaggtt atttaaatcg tggtaaacag ctccaccacc actaatacgg cgaactacct
    17281 caataccatt ttcgcgaaca taatcacggt tgatttcttc gatagtgttc tggtgacgac
    17341 caacaatgat agatggcttg ttaatccaaa gtaggaagat ttgatcctca tccaaaaggt
    17401 gtttaaaggc gtattcttcc aaggcaatat taaaagcagt gtcatttgaa tgattgataa
    17461 tgtatttcat gatatccctt tactttatat gatagagact ggaaataacc ttccagtcta
    17521 atctatcttc gttttatttt ttcttaggtg aatggatggc cattcctaga acatctgcaa
    17581 acgcttcgta catcacttca gagtaagttg ggtgcccgtg gatggtcttc agcatttcct
    17641 caacagtgat ttccatttcg atgatgcttg atgcttcgtt tattaattct gcggctgcag
    17701 gaccaataat gtgtacacca aggatttctc cgtatttctt atcagcgata acttttacga
    17761 aaccttgagc tgcgtcagat gcaatagcac gaccgttagc agcaaagtta aacttaccga
    17821 tggcaacatc gtatttctca cgggcttgtt cttctgtcaa acctactgct gctacttcag
    17881 ggagagtgta gatggctgca ggagtcaaat tcaatttggc aactgcatga tttcctttaa
    17941 gggcattttc agcggaaact tcacccatgc ggaaagctgc gtgagccaac atcttagtac
    18001 cgttgatgtc acctggtgca taaatgcctg gaactgaagt ttccatgtat tcattgacct
    18061 tgatacaacc acgatccaat tcaaactcaa cctctccaat accttcaagg tctggcatac
    18121 gaccaattga aagaagagct ttgcttgcga tgatatcgtc ttttccttca accttgatac
    18181 gaagttgacc attttcctca atgatttctt gcagtttagt accagtcaag atggtcattc
    18241 ctttacgctc aaggatcaag cgaaggttct tagaaacttc cgcatccata gctggaacta
    18301 tacggtccat catttcgata acagtcactt ttgaaccaaa tgtcatgaag gcctgaccga
    18361 gttcgatacc gacaactcca ccaccgatga taacaaggct ttctggcact tcgttcattt
    18421 caagaatgtc atcactagtc atgacaagtg gagattccat accagggaca ttgatcttgc
    18481 tgacttttga accaccagca agaatgattt tcttggtttc aagcaattca gagccattta
    18541 ccaagacgtt cttgtcttta gtgattgtac caattccttt atgaacagta actccgtagc
    18601 tacgaagaag tcctgcaaca ccaccaacaa gagtattaac aactttagat ttagtttcta
    18661 aaagtttttc catatcaaca gtgaagttag gattttcaat cacgatacca cgatttgcag
    18721 catgaccgat attttcaata atttcagcgt tatgaaggta ggtcttggtt ggaatacatc
    18781 cacggtttaa gcaggttcca ccaagttcag atttctcaac aagggcaacc ttaccgccga
    18841 gttgggcagc tttaatggct gcaacataac cagcaggacc tccaccaatc acaacgatat
    18901 caaaagcatc atcgctctta ccatcatcgt ttgaggtact tgctacaggt acagggctag
    18961 cttctggcga tgctgctcca gctgttggga tgttttccct ttcttcacca aggtaaccga
    19021 taacttccgt tacagggaca gtttcaccat ctcctttgag aatggcaatc aagtacccat
    19081 cttcttcggc ttccaattcc atgctgactt tatcagtcat gatttccaaa aggatttctc
    19141 cttcttttac aaattctccg acttttttat tccattggac gatttgtcct tctgtcatat
    19201 ccacgccggc ttttggcata attatttcta aggccatgtc ttccttcctt tatctatatc
    19261 ttaaaaatga atactcttgc tcttaaatca acattgagat tggggtttca atcaactctt
    19321 tcaagtcctt cataaactta gcaccagcca taccatctac gacacggtgg tcaatggtta
    19381 atcctaaact catgattggg cgaatcacaa tttcaccatt gacgacaact ggcttctcga
    19441 ttgtcgaact gacaccaagg atagctgagt tgggttggtt aataatcgga ccaaaggact
    19501 gaataccaaa cattcccaaa ttactgattg tgaatgttga attttgtaac tcacttggag
    19561 ccaatttacc atccaaggta cggccaataa catccttaaa ggctacaacc agttctgaaa
    19621 gactcatctt ctcagcattg taaacaacag gtgtcatcaa tccattatcc atcccaactg
    19681 ccatagcaag attgacatag ttgtgagtga taatagtctt gccatcttct gtcaatgaag
    19741 cgttgatgta tggatgtttc ataagagtct taacaactgc aagtgaaaga aggtctgtta
    19801 cagtagtctt cttcccagtt gcttccatga ttggctcaag aaccctctta cgaagagcca
    19861 acatttcagt catatcaact tcatagttga gggtgaaggt tggcgcagtc aagtaagatt
    19921 caaccatgcg ttgggcaata accttacgca ttggtgtcat tggaatacgc tcgatttcac
    19981 catatggtgt tacgttatca ggaacttctt ccactttttc aatctgagca ggagatttga
    20041 tgctatcgtt ttcgatattt tcaggaagca gggccaaaac atccttcttc atgattttac
    20101 cacgatgacc ggttccttgg atttcctgcc aagcaatgtt atgttcgagg gcaattcgtt
    20161 ttgcaagtgg cgaaatgcga accacgtttg tgtctttata agtttccacg tcttctttgt
    20221 ggacacgacc gtttgcacct gagccagaaa cgtcgtagag gtttatccct aaatcatccg
    20281 ctaactttct agctgcagga gtcgctctta gcttgtcatc agccatgacc tctccaattc
    20341 tatttatgat acaaagggcg tcaaaagcga ctgaaaaata ggaaatcgac gatggcttcg
    20401 atgaagccaa ggagatttat cttttttccg agcttttagc ccgtgctcta atctaagata
    20461 ttaatgacga agagctctgc acctaaaaga tacaaagttt ctcgtcagct ttattttatt
    20521 tacataactt atcttatgta actctattct ttgttataag tttttcggat tgcatctttg
    20581 atactttcaa ctgttggaat cattgcattt tctaggtttt gtgcataagg catcggcaca
    20641 tcttctcctg cacaacggcg gattggtgca tctagatagt caaatgcttc tgattctgaa
    20701 ataatagctg aaatttcacc gatatagcca cttgttttgt gggcatcgtt gaccagaaca
    20761 accttaccag tcttcttcac tgagtttatg atgatatcct tatcaagcgg aacaagggta
    20821 cgtgggtcaa caatttcaac tgaaattcct tcttctgcta attcttcagc agcttgaacc
    20881 acacggcgaa gcatttttcc ataagtaaca actgttacat ccgttccttg gcgtttgatt
    20941 tcaccaaccc caagtggaat tgtgtagtct ggatcaactg gcacttcccc tttttggtta
    21001 aattctgact tgtactcaag tataataact gggtttttat cacggataga agacttaagc
    21061 aggcctttca tgtccgcagg tgttccaggt gccacaacct taagtcctgg aatgtgagta
    21121 aaccaagact ctagagattg tgagtgctgg gcggcagagc caactccgtt accagctgca
    21181 caacgaacag tcattggaac ctgaccttta ccaccaaaca tgtaacgtgt tttagcagct
    21241 tggttgacga tattgtccat ggcaataaca gagaagtcca tgaaggtcat atcgacgatt
    21301 ggacgaagtc ctgtcatggc tgctcctgct gctgctccag agatggcagc ttcagaaatc
    21361 ggacagtcac ggacgcgttc tggaccaaat tcttcaagca ttccaacaga agtaccgaag
    21421 tctcctccga agacaccgac gtcttctccc atcaagaaca cattttcatc gcgacgcatt
    21481 tcctcagaca tagcaaggat aatggtgtca cggaaggaca ttgtttttgt ttccatttta
    21541 tctctttctc cttagtctgc gtaaatatct tcaaaggctg attcaagcgg tgggaatggg
    21601 ctttcctctg caaatttaac agaagcttct actgcttcct ttacttgcgc ttggatttct
    21661 tccaattctt cggcacttgc aatgttattt tcaataaggt aattgcggag gttttcgatt
    21721 ggatcttttt gtttccacaa ttccacttct tcacgcgtac gatatttacc agggtcagat
    21781 gatgagtgac cgagccagcg ataagttaca ctttcaatca agactggacc attgccactg
    21841 cgaacatggt ctacagcttt ctgaaatcct tcatagacat cgatgacatt gttaccgtct
    21901 tcgatgaaca ttccaggaat tccataagcg gcgctacgtt gatggatatg ttctatattg
    21961 gtcattttct tgatatccgc agagataccg taaccgttgt taatgcaata gaaaatgact
    22021 ggcaggttcc agatagaagc catgttcact gcttcgtgga aaacaccttc attggtcgca
    22081 ccatctccaa agaagcaaac aacgatttta ccggtatttt gcatttgctg actgagggct
    22141 gcaccgacag cgatccccat accaccacct acgataccat tggcaccaag gttcccagca
    22201 tcaaggtcag cgatatgcat agatccacct ttccctttac aggttccagt gtatttacca
    22261 aggatttcag ccatcattcc gttgaggtca atccctttag caatagcttg cccgtgtcca
    22321 cggtggtttg aggtaatcag atcatctgga ttgagagcta acatagcccc cacgttagct
    22381 gcctcttcac caacagaaaa gtgcgtcatt cctggcactt tccctttctt tactaattgt
    22441 gcaattttta agtccatgcg acggatttct tccatcttac ggaacatttc tagcaaaaga
    22501 tttttatcta aagttgacat cttcttgcct ttctaacttt cttcttacct tactatttta
    22561 ccgtttttgg caaatactgt caaagttttt ctaaaagaaa tttcacaaaa taaaaaagaa
    22621 aaccccgtga aaacaaggga ttttcttgtc aaggatattt tttcacaaac tttttagcgt
    22681 ttggattttg ctaaagattc aaatctcttc ataatcacag ttaaacgcca acggtagagc
    22741 gccccactca caatcaaact aataatcaag ccgatccagt aagaataagc tccaaaatct
    22801 gttagggaat caaatagcgt agccacaggg attgctacgc cccaataacc aagcaaacca
    22861 aggtaaaaag gaataactgt atccttatac ccccgcaaaa ttccctgaag cggtgccgca
    22921 aaggtatctg ctaactggaa gaaaagacta taagttaaaa aacgcgctgt caaatcgata
    22981 aattttgggt cgttaccata aagactggcc acatttcccc taaaaatgta aaggaaggtt
    23041 agggtgaagg ccgcaaaaat gagagcagtc catcttccta gaccaatata ggttttcgca
    23101 tcatcaaatc gcttggctcc cacttcatag gaaacgacaa tagccatagc cgatgagata
    23161 ctcataggaa aggcgtacat aagacttgaa aagttcatag ctgactggtg actagctata
    23221 atcaaggacg aaaacttagc cataatcaag ccaaccactg aaaagatagc cacttccgcg
    23281 aagacagttc ccccaatagg cagacctaaa cgaactcctt ccttaatgtt atccatatta
    23341 agtggaattc gtttctcaag gtgtaaggct ttgagcttct cctgtttaaa taaaaccaga
    23401 acagaaatcc caagcaagac ccagtaggcc aaggatgttc ctaaaccagc accagcccct
    23461 cccagttctg gaacaccaaa ggcaccgtaa atcaagagat agttaaatcc gctattgaga
    23521 gggagtaaca aaagcatgag gtacatggac agtttggtca agcccagcga atccagcaag
    23581 gaacgaatga cgctaaagag caacaagggg ataatcccga tagataaaaa ccaaagatag
    23641 cgaaccgcta ctgccgctac tgctgcttct aacccaatat gattcaagat tgttggtgcc
    23701 aagaaaagta ccatccccag caagaccaca gataggccca aggccaaata aataaattgg
    23761 taaaaatcag acgcaacttc ttcctttttg cctcgaccaa gatggtgacc aatgataggc
    23821 accaaggctg acacaatccc tgttagaaat gtaaagaaag gattccagat actggttgcc
    23881 atagatacac cagccaagtc catagtgttg tattgacctg tcattgcagt atcaacaaaa
    23941 gaggcagaat aattggcaaa ttggtagatc aggattggga agaaaatttt taaaaataat
    24001 actaacttct ctcgtaaaca ctttgtctta tacatacttc tctttctatt ctgatttatc
    24061 taaaccaaag agtttcagac catagttttt caaacttagc ggaggtttat tagattttga
    24121 agtagtatgc caacacgcac atgtacgaca ataatagctt ctaactaaac ctccgttatc
    24181 atattgaacc gcatggtcag ctttttcttt agtttcatat tgaattttgg aacgattagc
    24241 tgcgggacag taaattccac tattagattt cgcttgtctc tccctacgtt ttcgaaaata
    24301 attcatattc taactcctat caagcttgat agacgatttg tcccttacag atggtatatt
    24361 taacctgccc ttttaaggtt tcaccgatga atggtgaatt agctgctttg gaagcaaaat
    24421 gggagtccac aaggcggtca gccttggcat caaaaatagt gatatctgct ggaccattct
    24481 cagccaagta acctgcttta aagttgtaaa gcttggctgg gttgtatgtc attttttcaa
    24541 gtaattccat caagctcaac tcaccagctt ctaccaaata ggtcaagccg agagacaggg
    24601 atgtttctaa gccagtcata ccagatggcg ctttggtaat atcttcaaca tttttttcat
    24661 ctacatgatg aggcgcgtgg tcagtcgcaa taactgtgat gacacctgat ttgagacctt
    24721 cgataacggc acgacggtct gattccaaac gaagcggtgg attcatctta gcattgctac
    24781 cttgtgttaa aagaagtgct tctgtcttag agaaatgctg tggtgctact tctgctgtga
    24841 cttctgcacc taacccctga gcaaactcca ctactttaac actttcttcc ttagacaaat
    24901 gctggatgtg aacatgggct ttagttgcat aggcaatcat gacatcacgc gccatcatag
    24961 cgtactcagc caccccagta gcaccacaga tatggaaatg ttctctagca atattttcat
    25021 taaagccaag aacaccgttc aaacctggat cttcctcatg aaggctgata aaggtattga
    25081 gttttttggc ttcctccatg gcttccttga caatcttact gctctcaagc ggaataccgt
    25141 catcagagaa accaaccgca ccagcttcta aaagtgcctt aaagtcagtc aagtttttac
    25201 cattaaagtt tttagtaatg gtcgcaactg tcttgacatt aatcttctct ttggcagctg
    25261 actggagaac tgcttgcaaa gtctccacgt ctgaaatggt tggactggta ttagccatca
    25321 tgacgacagt agtaaaacca cctgcagcgg ctgctagggc accagtatga atgtcttctt
    25381 tatgtgtttg accaggttca cggaaatgca catgaatatc gaccaaacca ggagcaacca
    25441 catgaccagt agcatcaatc gtttctgctc cttcttccgt gatctcaggc gcaattttga
    25501 taattttccc atcttgaact aagacatcac aaacttgatc caaaccagac ttgggatcca
    25561 ttacacgacc atttttgatt agtagcatct gctttctcct ttattcatag aaatcaactt
    25621 gggtatccaa caatttatcc ccatcataaa caaacttggc tgaaaagaag ggtttatcct
    25681 ctaaaagcca ctcaacaaag gtgtggtcac cttcccaagt cggcttgctc aaaacctcat
    25741 catagggaac ccattctagc atcccctcat tgcagtcaat caagtcgccc tcaaactccg
    25801 tcaccttaaa aacataggtg taccagtcta attctggtgt aaattcagga aaagtgatga
    25861 caccttttag aactggcttg gctttgagcc ctgtttcttc aaggatttca cgtaccgcgc
    25921 attcctgggg cgtctctcct ctctctagct taccacccac accaatccat ttcccttcat
    25981 ggacatcatt gggtttctta ttacgatgga gcatgagcag ttctttccca ttatcaatgt
    26041 aacaaatcgt cgctaactga ggcatatttt ctccttatct aagccaatcg attggctctt
    26101 gtcctgtctc ttttaagaat gtattggcct tggaaaaagg cttggaaccc caaaatcctc
    26161 tataaaccga caaaggactt ggatgggctg attcaataat caagtgatga ggattggtaa
    26221 ctaaggcctt cttcttacgt gcataagctc cccagagtac aaaaacgact ggtctatcta
    26281 gatgattgac cacctgaatc acagcatcag taaaaggctc ccagatttga ccagcatgac
    26341 cattggcctg tccagcagga acagtcaaac aagcattaag aagcaagact ccttgctcag
    26401 cccaagctgt caaatcatga gatttcttaa ctccgatatc atctgacaat tctttcaaga
    26461 tattttgcaa ggatggtgga gctgggatag agtcaggtac ggaaaaactc aagccctgcg
    26521 cttgacctgg tccgtgatag gggtcttgcc ctagaattac caccttaact tcttcaagca
    26581 gtgttgtcaa gagagcctga aaaacctttt ccttgggtgg ataaataatc ccctgagaat
    26641 agacctgctc cataaactga ttgattttcc cgaaataacc ctcaggtaat tgcgccttaa
    26701 tcaaagcatg ccaagacgag tgttccatag ccgactcctt catttttact gcctctatta
    26761 tagcaaaaag tggctatgga aaccactttt tacagtttat ctaaagattt aataaatcga
    26821 ctatatacga tttgaatacg tgaatacagt ttataaagac tggctatttt ttataattac
    26881 tttttaaatc attaagcatt ttactacctc tttcgaagat tatcttttct gaaatatttt
    26941 taaacatatt aaaatccatt tcagaaaaag gagtttcttt agaaacttgc catatagtct
    27001 ttaaataatt tttttctaaa aagtcgtcaa aattagaaaa aaatcgaaaa tacaatgcat
    27061 tctcttggtg taaaatcgct ctttttaaag gataatactc tttaatatta ttaacttttt
    27121 gttcgtaggc atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat
    27181 ctcccataca gccattacga ttcatattga ggctatattt tcgattagta agataattca
    27241 gaaatatatt tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat
    27301 ccccttcttt gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt
    27361 tcttatcaaa aaacttaaaa agagattgat aaatactatt tgctaattga caagtgtcag
    27421 atgtaaattc ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt
    27481 caatagtaat attagctttt ttgtagtcat tagctcgtct cctttaaaat gtgatctttt
    27541 caagaatatt tttatctaaa caatccagca agtcttggta agaatagact tcgtaagtcg
    27601 gctgggcttg tgtgtgattt tcgaggtgat gaggattata ccagatagtg tcaatccccg
    27661 cattattgcc accttgaatg tcgacggtta gagaatctcc aatcatcagc gtcttttctt
    27721 tactaaatcc agcaatttgc tggccaatct tttcataaaa aagagcatcc ggcttttgag
    27781 tttgcaactg ttctgagata aagacttgat tgaaataagg tgctagacca gattgagcca
    27841 aacgtcctgt ctgaatggca gtaatgccat ttgtcgcagc atacaagtta taatcacgcc
    27901 caatgaggct gtccaagaga tcatgagcgc ccgatagtgt ttgtccctgc tgggcgaggt
    27961 aaaattggta acgctgggca agaaaactac cgtctttttc ttgtccaaaa tgagcaaata
    28021 aacgagaaaa gcgcgtgtta accagctctt gtttactgat tttcttcagc tccaagtctt
    28081 tccagagagc cttgttcata ggaacgtaat aatctttata agcctgaata tccgcaactc
    28141 cttcttcttt tagaagttgg gtcaaagcca catcctcagc agcatcaaaa tcaagaagag
    28201 tgtggtcgag gtcgaagagt agaaatttgt agaacaattt gaggttttcc tttctgaaaa
    28261 ttcattaaga acattatatc ataaagcacc tcatacaatt aactaattta atcacttaaa
    28321 aaaaattcga acactttcta tacaactgac agctcaaatc tttcagaata gaacaatact
    28381 aactatcgaa caccctgtct tcataaatac atatgtaatt ctaggcctag aattcctata
    28441 aactaaatgc tttcatactc ttccaagtaa ttgattgcct taaattttaa tttttgaagg
    28501 tttctaaagc tagaatagcc ccatcacaat cagttttgat tgattcacaa tttagaaaca
    28561 ctatagtttc actcctgtta aaataaaaag gaactgcata aagcaatccc tttctgattt
    28621 tgaaatcatt tacttaacat tttatagttg agataatcaa tagcttatct ataaaaagag
    28681 ttatagtaaa attccttatt tattgatttc aagctccgct aactgtattt gaataactga
    28741 cagttctgca ccagcctgaa gaagagcagc tgcattatag gcaccttcta caattggaac
    28801 cctgttgatg atgatacttt tatcactgaa atcagtcacc atttttaagt tcattttagc
    28861 agaacctagg tcaaaaaagg caagtaaagt atctgctgga ttttcggaaa caaccctatc
    28921 tacttgatca aaactcgttc caattcctcc gccctcggtt cctcctacat aagtaatcgg
    28981 aacatcttta gctactttac taatcagttc aacaacacct tctgcaatgt gtttggaatg
    29041 tgaaacgata acaagaccaa taccaatact ttccatcaaa ccactccagt ttctaaaata
    29101 gcagtaaaga gtaatcctga tgagaatgat ccaggatcaa tatgtccaag aaaccacatg
    29161 ctcctaagac aagagctaac agactggcca tcaataatag tattgttctt tttttcatca
    29221 ttactcctta actagtgttt aactgattaa ttagccagta aatagtttat ctttatttac
    29281 actatctgtt aagatatagt aaaatgaaat aagaacagga cagtcaaatc gatttctaac
    29341 aatgttttag aagtagaggt atactattct agtttcaatc tactatattt tgcacatttt
    29401 catgaaaaaa atgagaacta gaactcacat tctgctctca tttttcgttt tcccgttctc
    29461 ctatcctgtt tttaggagtt agaaaatgct gctaccttta cttactctcc tttaataaag
    29521 ccaatagttt ttcagcttct gccataatag tattgttgtc ctgggtgcca aatagtaaat
    29581 tattttttaa tcctgtgaga gtctctttgg cattggactt gataattgga tcctggattt
    29641 ttccaagtaa atcttcagcc tctctcagtt tttcttcaac cttttcagtc tcgacctgag
    29701 gttcttctga ttcctctggt gattcttctg gttcctctgt tggttttgga gactctggtt
    29761 tctcgctttg cggtttctct tctcgagggg tttcttcctc aggtttttct gtctgaggtt
    29821 tctcctcgct tggtttttcc gtttgattgg tatcagcttg accatttttg tttctt
//
LOCUS       DBEJZJ010000022        29605 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000022 DBEJZJ010000000
VERSION     DBEJZJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.22"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            172..309
                     /locus_tag="ACL3R8_001301"
     CDS             172..309
                     /locus_tag="ACL3R8_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314172.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            340..1185
                     /locus_tag="ACL3R8_001302"
     CDS             340..1185
                     /locus_tag="ACL3R8_001302"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR1314173.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1332..2393)
                     /gene="dinB"
                     /locus_tag="ACL3R8_001303"
     CDS             complement(1332..2393)
                     /gene="dinB"
                     /locus_tag="ACL3R8_001303"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR1314174.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2741..5065
                     /gene="pflB"
                     /locus_tag="ACL3R8_001304"
     CDS             2741..5065
                     /gene="pflB"
                     /locus_tag="ACL3R8_001304"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR1314175.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5432..5650)
                     /locus_tag="ACL3R8_001305"
     CDS             complement(5432..5650)
                     /locus_tag="ACL3R8_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314176.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5977..6261)
                     /locus_tag="ACL3R8_001306"
     CDS             complement(5977..6261)
                     /locus_tag="ACL3R8_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314177.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7693..8916)
                     /locus_tag="ACL3R8_001307"
     CDS             complement(7693..8916)
                     /locus_tag="ACL3R8_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR1314178.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9084..9203
                     /locus_tag="ACL3R8_001308"
     CDS             9084..9203
                     /locus_tag="ACL3R8_001308"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1314179.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLI"
     gene            9222..10406
                     /locus_tag="ACL3R8_001309"
     CDS             9222..10406
                     /locus_tag="ACL3R8_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR1314180.1"
                     /translation="MLISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAY
                     RLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSL
                     FMAITIGLVTAEIYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGL
                     EAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDP
                     VWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKT
                     LGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTG
                     VILPWTMPPIIGGFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVG
                     GK"
     gene            10408..12294
                     /locus_tag="ACL3R8_001310"
     CDS             10408..12294
                     /locus_tag="ACL3R8_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGR1314181.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12462..12806
                     /locus_tag="ACL3R8_001311"
     CDS             12462..12806
                     /locus_tag="ACL3R8_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1314182.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12816..14228
                     /gene="lacG"
                     /locus_tag="ACL3R8_001312"
     CDS             12816..14228
                     /gene="lacG"
                     /locus_tag="ACL3R8_001312"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR1314183.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14298..15977
                     /locus_tag="ACL3R8_001313"
     CDS             14298..15977
                     /locus_tag="ACL3R8_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1314184.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16103..17542)
                     /locus_tag="ACL3R8_001314"
     CDS             complement(16103..17542)
                     /locus_tag="ACL3R8_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR1314185.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17546..18895)
                     /gene="trkA"
                     /locus_tag="ACL3R8_001315"
     CDS             complement(17546..18895)
                     /gene="trkA"
                     /locus_tag="ACL3R8_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR1314186.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19084..19932
                     /locus_tag="ACL3R8_001316"
     CDS             19084..19932
                     /locus_tag="ACL3R8_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR1314187.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            19947..20495
                     /locus_tag="ACL3R8_001317"
     CDS             19947..20495
                     /locus_tag="ACL3R8_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR1314188.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            20502..20714
                     /locus_tag="ACL3R8_001318"
     CDS             20502..20714
                     /locus_tag="ACL3R8_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002668516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314189.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            20816..22498
                     /locus_tag="ACL3R8_001319"
     CDS             20816..22498
                     /locus_tag="ACL3R8_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314190.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            22483..23313
                     /locus_tag="ACL3R8_001320"
     CDS             22483..23313
                     /locus_tag="ACL3R8_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1314191.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            23506..24009
                     /locus_tag="ACL3R8_001321"
     CDS             23506..24009
                     /locus_tag="ACL3R8_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR1314192.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      24063..24297
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            24462..25025
                     /locus_tag="ACL3R8_001322"
     CDS             24462..25025
                     /locus_tag="ACL3R8_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR1314193.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            25015..25665
                     /locus_tag="ACL3R8_001323"
     CDS             25015..25665
                     /locus_tag="ACL3R8_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR1314194.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            25693..26082
                     /locus_tag="ACL3R8_001324"
     CDS             25693..26082
                     /locus_tag="ACL3R8_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR1314195.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            26087..26536
                     /locus_tag="ACL3R8_001325"
     CDS             26087..26536
                     /locus_tag="ACL3R8_001325"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1314196.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            26664..27251
                     /gene="rpoE"
                     /locus_tag="ACL3R8_001326"
     CDS             26664..27251
                     /gene="rpoE"
                     /locus_tag="ACL3R8_001326"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR1314197.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            27641..29248
                     /locus_tag="ACL3R8_001327"
     CDS             27641..29248
                     /locus_tag="ACL3R8_001327"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR1314198.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         8826 a         5145 c         6271 g         9363 t
ORIGIN      
        1 gtggtttaag aacagttttt cctggaacat tcaaggctgt aacatcgtgt ttatttttag
       61 cgatatcaat gcccacataa agcatgggag tacctccaga tatagtattt caagtctact
      121 tggttatcca cgaatttttt gccttgttac cttagacgag atcaaacgtc tatgcgttat
      181 caaactcatt accaattgaa acaaaagctg tggttagagc ctttcggaaa tcgtcaagcg
      241 attggaggaa atgaactaat ccacagtggc ttattccaag tataccactt gggctttggc
      301 agtagctaac tgcgctaatt ataatatagg gagtaatcta tgtatcttat tgaaatttta
      361 aaatctatct tcttcgggat tgttgaagga attacggaat ggttgccgat ttccagtaca
      421 ggtcacttga ttttagcaga ggaattcatc caataccaaa atcaaaatga agcctttatg
      481 tccatgttta atgtcgtgat tcagcttggt gctattttag cagttatggt gatttatttt
      541 aacaagctca atccttttaa accgactaag gacaaacagg aagttcgtaa gacttggaga
      601 ctatggttga aggtcttgat tgctacttta cctttacttg gtgtctttaa atttgatgat
      661 tggtttgata cccacttcca taacatggtt tcagttgctc tcatgttgat tatctacggg
      721 gttgccttca tctatttgga aaagcgcaat aaagcgcgtg ctatcgagcc aagtgtaaca
      781 gagttggaca agcttcctta tacgaccgct ttctatatcg gactcttcca agttcttgct
      841 cttttaccag ggactagccg ttcaggtgca acgattgtcg gtggtttgtt aaatggaacc
      901 agtcgttcag ttgtgacaga atttaccttc tatcttggga ttcctgttat gtttggagct
      961 agtgccttaa agattttcaa atttgtgaaa gccggagaac tcttgagctt tgggcaattg
     1021 tttttgctct tggtcgcgat gggagtagct tttgcggtca gcatggtggc tattcgcttc
     1081 ttgaccagct atgtgaaaaa acacgacttc accctttttg gtaaataccg tatcgtgctt
     1141 ggtagtgttt tgctacttta cagttttgtc cgtttatttg tataagaaaa accttgaagg
     1201 ggcaactctt caaggtttta tactcttcga aaatctcttc aaaccgcgtc agctttatct
     1261 gcaacctcaa aacagtgttt tgagcagcct gcggctagcc tcctagtttg ctctttgatt
     1321 ttcattgagc tttaaaatcc agtcatggta atccccaata ggcggacacc tctttctttc
     1381 ttgcttaatt cttcatagag ttgcagggct atttggctta tctgactagc atcttgtgtt
     1441 ttttgagcaa gactttttcg tttggtaaga gttgaaaagt cctcgtagcg gattttcaaa
     1501 atgacaattt ttccagcttt ttcttgttga tgtagattga gagcgacttt ttctgataga
     1561 agagtcagct cttttttgat atcttcctca gcaaggagaa tcttcccgta ggttttctcc
     1621 ttgccgattg atttacggat gcgattggat ttgactggag agttgtgaat gccacgagcc
     1681 tttcgataca gatcatagcc tagtctacca aaacggtcta ttagggttac ctcaggaact
     1741 tcaagtaaat cagcaccagt aaaaacgccc atttgatgaa gacgttctac tgtctttttt
     1801 cctactccat gaaatttgga aatatccatt tgtttgagaa aatcctcagc ctgttcaggt
     1861 agaatcactg tcaaaccatg tggtttttga taatcactcg ccattttagc taagaatttg
     1921 ttgtaagaaa cgcctgcgga agcagttaga tggagttctt gccagatatc tttttgaatg
     1981 aggcgagcaa ttttgaccgc tgacttgata ccgagtttat tttctgtcac atccaaatag
     2041 gcttcgtcaa tgctcatggg ttcaatcaaa tctgtatagc gcttaaaaat agctcgaatc
     2101 tggagtccca cagacttgta tttctcataa ttccctgaga taaagacagc ctggggacaa
     2161 cgttcataag cttccttgga actcatggca gaatggacac caaaagctct tgcctcataa
     2221 ctacaggtag aaacgactcc ccgtccacct gtttgccgag ggtcgcttcc aataatgaca
     2281 ggttttcctc tgagtttagg attatccctg atttccactg cagcaaaaaa ggcatccatg
     2341 tcaatatgga tgatttttct tgacaaatca tttaacaaag gaaaaatcaa catgcctagc
     2401 acctttttat actcttcgaa aatctcttca aaccacgtca gctctatctg caacctcaaa
     2461 acagtgtttt gagcaatctg cggctagctt cctagtttgc ttttcgattt ccattgagtg
     2521 ttactgctta ttttctttta ttataccctt ttttctgaaa aaaagaaaaa aggactttat
     2581 tttttcaaaa atataataca gtttgaaata aaatatagac tgttttagaa aagaaagtgt
     2641 aaaaataggg aattttcact tgttgaaatc ggttactata tggtatactt gtcttatgaa
     2701 tgtaacagat gactgttact agaaaaaaga ggacattaat atggttgtta agacagttgt
     2761 tgaagcacaa gatatttttg acaaagcttg ggaaggcttc aaaggcgtag attggaaaga
     2821 aaaagcaagt gtatcacgat ttgtacaagc taactacaca ccttatgatg gagacgaaag
     2881 cttccttgca ggaccaacag agcgttcact tcacatcaag aaaattgtag aagaaactaa
     2941 agcacactac gaagaaactc gtttcccaat ggacactcgt ccaacatcta tcgctgatat
     3001 ccctgctgga tttatcgaca aagaaaatga agttatcttc ggtatccaaa acgatgaact
     3061 cttcaaattg aacttcatgc caaaaggtgg tatccgtatg gctgaaacta ctttgaaaga
     3121 aaatggatac gaaccagacc cagctgttca cgaaatcttc actaaatatg taacaacagt
     3181 taacgacggt attttccgtg cctacacttc aaatattcgt cgcgctcgtc acgcacacac
     3241 tgtaactggt cttccagatg catactcacg cggacgtatc atcggtgttt acgcacgtct
     3301 tgctctttac ggtgcagact acttgatgca agaaaaagta aatgactgga atgcaatcaa
     3361 agaaatcgat gaagaaacaa tccgtcttcg tgaagaagta aaccttcaat accaagcatt
     3421 gcaacaagtt gttcgcctgg gtgaccttta cggggttgat gttcgcaaac cagcgatgaa
     3481 cgtgaaagaa gcaatccaat gggttaacat tgctttcatg gctgtctgcc gtgtgattaa
     3541 cggtgctgct acatctctag gtcgtgtacc aatcgtattg gacatctttg cagaacgtga
     3601 ccttgctcgt ggtacattta ctgaatcaga aatccaagaa ttcgttgatg atttcgttat
     3661 gaaacttcgt acagttaaat ttgctcgtac aaaagcttat gaccaattgt actcaggtga
     3721 cccaaccttt atcacaactt ctatggctgg tatgggtaac gacggtcgtc accgtgttac
     3781 taagatggac taccgtttct tgaacactct tgacaacatc ggtaactcac cagaaccaaa
     3841 cttgacagtt ctttggactg acaaattgcc atacaacttc cgtcgctact gtatgcacat
     3901 gagccacaaa cactcttcta tccaatacga aggtgtaaca acaatggcta aagacggata
     3961 tggtgaaatg agctgtatct catgctgtgt gtctccactt gatccagaaa atgaagaaca
     4021 acgccacaac atccagtact tcggtgctcg tgtaaacgtt cttaaagccc ttcttactgg
     4081 tttgaatggt ggttacgacg atgttcacaa agactacaaa gtatttgata tcgaaccaat
     4141 ccgtgacgaa gttcttgaat ttgaatcagt taaagcgaac tttgaaaaat ctcttgactg
     4201 gttgactgac acttacgtag atgccttgaa catcatccac tacatgactg ataggtacaa
     4261 ctacgaagct gttcaaatgg ccttcttgcc aactaaacaa cgtgccaaca tgggattcgg
     4321 tatctgtgga tttgctaaca ctgttgatac attgtcagct atcaaatacg ctacagttaa
     4381 accaatccgt gacgaagatg gctacatcta cgattacgaa acaatcggtg actacccacg
     4441 ctggggtgaa gatgacccac gttcaaacga attggcagaa tggttgatcg aagcttacac
     4501 aactcgtcta cgtagccaca aactatacaa agacgcagaa gctacagtat cacttttgac
     4561 aatcacatct aacgttgctt actctaaaca aactggtaac tcaccagttc acaaaggtgt
     4621 atacctcaac gaagatggtt ctgtgaactt gtctaaactt gaattcttct caccaggtgc
     4681 taacccatct aacaaagcta aaggtggttg gttgcaaaac ttgaactcac tttctagcct
     4741 tgactttagt tatgcagctg acggtatctc attgactaca caagtatcac ctcgcgctct
     4801 tggtaagact cgtgatgaac aagttgataa cttggtaaca atccttgatg gttacttcga
     4861 aaacggtgga caacacgtta acttgaacgt tatggacttg aacgatgttt acgaaaaaat
     4921 catgtcaggc gaagacgtta tcgtacgtat ctctggatac tgtgtaaaca ctaaatacct
     4981 cactccagaa caaaaaactg aattgacaca acgtgtcttc cacgaagttc tttcaatgga
     5041 tgacgccttg gatgcattga gctaatcaag ttcttgaata ataaaaagga accctcggtc
     5101 aaacgactga gggttttgtg cttgggatag tatgagcaat tccttcggcg caatatgcaa
     5161 tgtttttggg aaggaatagt ggaccgaatc tgaaatataa tagattgaaa ctagaatagt
     5221 acacctttac ttctaaaaca ttcttagaaa tcgatttgac tgtcctgatc gatttgtcct
     5281 attcttattt cattttacta tagtccgctg aaacggctca aacagtgcta gaaattgact
     5341 ggaattctct aagtgatttg ttccgatttt atttcatttc atcataaaaa taagatgact
     5401 ggctaattga caatcatctt gtttgatact gttaataaaa ttcgcgaagt ttatcttgat
     5461 tttctttaaa aaatttttct aaccaatcca taccataagc ataactaaaa ccttctaata
     5521 gaacagagag gtcaatagta tcaaatccca tgtcttttaa atatttaaag gtatcgaatg
     5581 gtgaatgaaa gtttttgtat ttaataattg caccaatatc ttgcaaatcc tgctctctga
     5641 tactcatcat cttcattcct aacacatact caatagggac tactaaaacg gtcagattct
     5701 caaatgagta caaggattcg cataaactta agggaggttg tttgttcata tttgctttgc
     5761 aacatgattg ttgagccata actcttcgtg gatgttaaga ttaaactgtt ttcctacacg
     5821 agcaataatt tcattgattt tctgattttg gtcataaaaa gcatcaacat cttgtgtggc
     5881 acgtaaacca tgatattcta agacataacc ataattgtta aagtcagatt ttcctgaatt
     5941 aatttcttat ttagggcttg gaagaccggt ttcattttat ccatgtttgt atttctccat
     6001 caatttttga acattggtta acttagcagg tttatttaat gaaatcacat atttatgagt
     6061 tggagtatgc tcttgaaagg catacttcaa gctaattttt tgaaaacggg ttagttcttt
     6121 ggagtctagc aacttttcta catcttggtt tgttaaataa gaatagtctt caaaaataac
     6181 ttttcgcaaa tagcgaaacc aatggcttgc gttgaattgt gattgtttgg atgcctgtat
     6241 catataatcg taccaatcca ttgtcttcct cctataaaat ttagtttata ttattgtagt
     6301 ttatattcaa aaatgtagtt tttcttaatt agctcgtatc tataggatga tactgaaaat
     6361 cttcttgttg ctttaaatca caatcgaaaa attctgtttt tcatcttaga aaagaatgtt
     6421 tagaaatgta aaatgaacct tttttcttat ccgaaaacct tactaaagta tataatttag
     6481 gcagtcaatt ctgtatgata atgtttgtac tatcgtcgag tttttgcttg attgcctaac
     6541 gagataaatt ttagaagagt tttcggtgtg atttgacaag tttctgactg gaaggatagt
     6601 tacactagta ttgtttatta aaatgagcag atagagaaaa tttggaatct atttgcttat
     6661 tatcaatcgt ttttttagct tatttgtctt agattggtat agaactgagc tatggattaa
     6721 tcttcttcta tcttatcctg ttcctaaata tgttggtaga aaaatgaagc agttgttacg
     6781 agtgtctgta ttgggaaaaa ttttgtctat agaattcttt aaatgatatg aaggctagga
     6841 atgccaaaac actgacatat ttcgtttaaa gtctatccag tctcttcaat tgtatttgta
     6901 gaaatgctat cagtaatata ttcgcgaaca ctatgattta caacagtgtg gtcgtacatc
     6961 tttgtaactt tattatacaa caaccattta caggtgtaaa gttgagcagt gtctttagta
     7021 aatttaggga cttgttttgt catagttttg atacctgtat tcgttgtttc atgagcattt
     7081 gacgtttctt ttcatgtagg catttcaaca attagaatga tatttttccg aggatgaact
     7141 tatatattgt gactttttag agttatgatg cctcttgatt tgactatcgc tatcaatttc
     7201 atccactttt acagtttcat ggttttatga accgaaacat ctaggtacag gttttagcat
     7261 caattgattg tttttgagcc atatgaagtt gaaacgtgga gatgcttttc ttgtgataac
     7321 gccctattca aagaggaata accgtttttg gagagagttc agtactatgt ggcgctaaat
     7381 actatatgta aaacatatat taaacaagat ttaactaagg agaattgtaa aaacaaaaat
     7441 gagaatttca tataaagttt attctaggag tatgtatctt gaataaaaat cgttatttaa
     7501 gttcagggtt atgatgaatg tttttataat aataaaatgc agctagaaga aaagttattt
     7561 taatataaat cactcaacat agagagaagg cggtttccta tatggaagtc gtcttgtttt
     7621 catattgtct aaatacgaga tatctactac aggttatagt tgatttaaac aggtctatag
     7681 atttctaata tattaaggtg aaataatatc ttgtaataca ttgctatgtt ctatgaaaaa
     7741 agcgacgata gctaatgcac aagctcctat acttccacga tgtttgttgt aaggtaaaat
     7801 ttcaatttct atattacgag taaagggaac gaagtggagc tggtcttgga ttttatccct
     7861 gacttcatga gtgaaaggtt gataattaag caattgactg ttgatataga ttttatcagc
     7921 aggattgatg aggaggagat ttgcaataga agtggctaat aaattgactc ctttatcaat
     7981 ttgttgacgt aaagcggagt cgcctaaatt ataagccgtt aaaagggtgt ctaaatgaat
     8041 gtctttttca gtctttacaa ggctttttag tacagttagt tgggaatttt taaataataa
     8101 ttgggcgtgt ttgattaacc aagcatccga aatatatgtt tgtaaacaac ctttttttcc
     8161 gcattcacaa tattgcccat tcaattcgac aatggtgtgt ccaatttctc cgatataagg
     8221 atttttagag gctcctattt tttcttttgt gaaaaaggaa gtgtaaatac ctaatccagc
     8281 gtgtaggaaa ataaagttat cgggggtatt gtgtggatta aaaaggtatt gtcctatagc
     8341 catacaatcg atattatttt ttacaataaa aggaaaattg aatcttttaa ttacatttaa
     8401 taaattaaaa gattcccata tggggttgtt tgtaatgata cttccggagt ctttgttata
     8461 atgtccaggt attgataagc caaatccaag taattttgtt tccaaaggga cgtactctat
     8521 agctgttttt atcatattgg taatggtgga attgatttct gaaataggat aatcttcatt
     8581 caaaatttct gtctcgaaaa gagttttccc ttgtaagtca catagactga gaaagatacc
     8641 taggacgttt atttcaatac ctccaacaac atacggaata ttatctgtga tagaaatagt
     8701 ttttctacgt cttccagatc cggaaaactc gctaaattca tcaccagttt cgtatatgag
     8761 ggactgttcg cttagctctt ttatgatgtt agtcgttgtt gctggagtaa gtcctgtttc
     8821 attaacaata tctgtacggg atgttgctgg atttcgatat agaaactcca gtatagtggc
     8881 tctattttgt aaaaaggctg attgttttgt aatcatttgt ttcctccttt ggtttatttt
     8941 atattaaaca taagaaaaaa tcaattaaaa ttattatttt atacaaagaa aaaaatattg
     9001 taaaaacaac aaaaaatata ttgacaacgc tttctgttag tggtatattt aatttataaa
     9061 aaataaaaaa aggagttccg gtgatgaaca atattttagc gtttttagaa acaaaagtcg
     9121 ctccgtttgg tgaaaaagtt ggcaaccaac ggcatttgaa agctattcgt gaaggattta
     9181 tgatggcaat gcctttgatt tgagtcggat ctttatttct tattctaatc agttggcctc
     9241 aagaggattt tacaaattgg ctgaatagtg ttggattgct aagtatcttg acaactatga
     9301 atcagtcaac agtagcgatt atctccttgg tcgcttgttt cggtattgcc tacaggttgt
     9361 cggaaggata tggtacagat ggtccgtcgg cagggatcat agccttatcc agttttgtat
     9421 tgatggcacc tcgtttttcg agtatggttt atgataaaaa tggggagcag gtcaagcagt
     9481 tatttggcgg cgcaatacca ttttctagcc tgaatgcatc ttctttgttt atggcgatta
     9541 ctattggatt ggttacagca gagatttatc gtatgtttat ccagcgcgga attacgataa
     9601 aaatgccaag tggtgtccca gatgtggtaa gtaaatcatt ttcagctctt ttacctggct
     9661 ttactacttt tgttttgtgg gctctggtct taaaaggtct tgaagcggca ggagttgcag
     9721 gaggtctcaa cggactccta ggtgcaattg ttggaacacc gcttaagtta attgcaggaa
     9781 cgcttccagg tatgattcta tgtgttattg taaactcatt cttttggttc tgtggagtta
     9841 atgggggaca agttttaaat gcttttgtag atccagtttg gttacaattt actacagaaa
     9901 accaagaagc tgtggctgca ggacaaacac tccaacacat tattacatta ccgtttaaag
     9961 atttatttgt atttattggt ggcggtggag cgactattgg tcttgcgatt tgtctcttcc
    10021 tatttagtaa gagtcgtgcg aataaaacat taggtaagct agctattata ccgtctattt
    10081 ttaatatcaa tacagctatt ctatttacgt ttccaacagt tttaaatccg attatgctga
    10141 ttccgtttat tgctactcct acaatcaatg ccttaattac ctatgtatca atggctgtag
    10201 gattagtacc ctacacaaca ggtgtaatcc ttccgtggac aatgccaccg atcataggag
    10261 gcttccttgc gacaggagct agttggcgag gagctctatt acaagttgtt ttgattttgg
    10321 tttctgtagc aatttattat ccattcttca aaattgcaga taaacgcaat cttgaaaaag
    10381 aaaaagctac tgttggaggg aaataagatg gttatcagag tatttgatca gcagaaaaat
    10441 acttattcta gctttgcctt agaggaatta agttactata taaatcgggt ctttaagact
    10501 gacatagaac ttgtcgagga gaaggaagcg gatatttttg taggattagt caataaagag
    10561 gatagaaaag accatgttct tatctcatta gacaagggta aggggagaat tgagtctaat
    10621 acaattgtag gtttacttat tggaatttac cgaatgtttc atgaatttgg ggttgtgtat
    10681 actagaccag ggcgcggaca tgactttgtt ccagagttac gatttgaaga ttttttagat
    10741 aaagagctat ctatagatga aacagccagt tactatcata ggggagtatg tatagaggga
    10801 gcagattcat ttgaaaatat actagatttc attgattggc tacctaagat tgggatgaac
    10861 agttttttca ttcagtttga aaatccctat tcttttttga aacgttggta tgaacatgag
    10921 tttaatccat acctaaataa agaaaaattc tcaaatgaat tagtacaaga attgagtgat
    10981 aggttggata aagaattgca aaaaagaggt cttattcatc atcgtgttgg tcatggatgg
    11041 acaggtgagg ttttaggtta ctcttcaaaa tttggctggg aatcaggtct tagtatttca
    11101 gaggagaaga aaccctatgt cgctgaaata aacgggaaac gagaattatt taatacggct
    11161 ccgattttaa ccagtctgga tttttcaaat ccagatgtgg cggataagat ggtagaaatt
    11221 atcaaggatt atgccaagaa aagacctgat gttaactact tacatgtatg gttgtcggat
    11281 gctcgtaata atatttgtga atgcgaaaac tgtagacaag aattggtttc ggatcagtat
    11341 attcgtattc tcaatcaatt ggatagggct ttaacgagtg agggattaga tacaaagatt
    11401 tgttttctgc tttaccatga gttgttatgg gcgcctcaga aagaaaaatt agataatcct
    11461 gaacgcttta ccatgatgtt tgcaccgatt acaagaacat ttgaaatgag ttatgcagat
    11521 gtagattttg acaattccat acctacgcct aaaccttatc tgcgtaataa aattatactt
    11581 ccgaattctc ttgaggaaaa tttatcttat ctttttgagt ggcaaaaaac atttaaagga
    11641 gatagtttcg tatatgacta tcctttaggg cgtgctcatt atggcgattt aggctatatg
    11701 aaaattagtc aaaccattta cagagatgta tcttatcttt ctaacctaca tttgaacggt
    11761 tacatttcgt gtcaagaatt acgtgccgga ttccctcata attttcctaa ttatgttatg
    11821 ggggaaatgc tctggaagaa gacaagaagt tatgaagaat tgattgaaga atacttttct
    11881 gctttgtatg ggtcaaattg gcagtctgtt gttgaatatt tagaaaaatt atccagttat
    11941 tcctcatgtg attattttaa tgcaattggc agtcgtcaaa atgatgtttt agcgaatcat
    12001 tattatatag cttacaatct agctgataat tttttgccaa ttattgagga aaatatttct
    12061 aagttattaa atagtcaaaa ggatgaatgg aaacagctca gttatcatcg tgaatatgtt
    12121 gttaagatgg cgaaggcttt atatcttcaa gcaaccggaa aaacaaggca agctcaagat
    12181 gaatggagaa atgtgttgaa ttatatccgt gggcacgaat tgctatttca atctaatttg
    12241 gatgtttatc gtgtaattga agtagcaaaa aattacgctg gtttccactt ataaatcata
    12301 agtatagaaa atgaaccaag gtattcagag aagattgatc ctaaatatta tgaaatttaa
    12361 ggatttttaa gatatttagg gtcgactttc tatttatatc gtagcgaagt cattttaata
    12421 atgatgtgta aaagatggat caagattgag gaggaagaaa gatgaaatca aaagaagaaa
    12481 taaatatgct tggttttaca attgtcgctt acgcaggaga tgcaaggtca gatttgatgg
    12541 atgctttggc gtttgcgaga gatggatatt ttgaacaggc aagagaattg gttgagtctg
    12601 caaacgactc aatagtgtct gcccatcgag aacagactaa tttattagcg gaggaggcat
    12661 ctggagataa ttttgaagtg agttttatca tgattcatgg tcaagatacc ttgatgacaa
    12721 cgatgctatt gtatgatcag gtcaagtttt ttattgatga atatgaacga attcgaaaga
    12781 ttgaagaaca tattggtttg caatgaggat tagtcatgga aaatttacag gttaaagcct
    12841 taccgaagga gtttttatta ggagctgcta ccgctgctta tcaagtagag ggtgcaacta
    12901 gggtagatgg caaaggaaca aatatgtggg atgtttattt gcaagaaaac agtccgttct
    12961 taccagatcc agctagtgat ttttattatc gttacgaaga ggatataact ttggcggcag
    13021 aacatggttt gcaggctttg cgtttatcta tttcttgggt tcgtatattt cctgatatag
    13081 atggggagcc taatatatta gctgttcgtt attaccatag agtctttcag tcttgcttaa
    13141 aacataatgt gattccgttt gtttctttac atcattttga ttcgcctcag aaaatgttag
    13201 aaacagggga ttggttgaat agagagaata ttgatcgttt catacgatat gctcgctttt
    13261 gtttccaaga atttacagaa gtcaagcatt ggtttacaat caatgaactg atgtctcttg
    13321 ctgcaggtca atatatagga ggtcagtttc ctccaaatca tcattttcaa ttatctgaag
    13381 caattcaagc gaatcataat atgttgttgg cgcatgctct tgcagtcctc gaatttcatc
    13441 aattaggaat tgagggagag ataggttgta ttcatgcttt aaagccaggc tatcctattg
    13501 atgggcaaaa agaaaatatt ttggcagcta aacggtatga tgtttataat aataaatttc
    13561 tattagatgg aacttttttg ggctactaca gtgaggacac gctttttcac ttgaatcaaa
    13621 tattggaagc taataattct agctttatta ttgaagatgg tgatttagaa attatgaaga
    13681 gagctgcagc tcttaatacg atgtttggga tgaattatta tcgttcagaa tttattcgtg
    13741 aatacaaagg tgaaaataga caagaattta attcaacagg aataaaagga cagtcttctt
    13801 ttaaattaaa tgctctaggt gaatttgtaa aaaaacctgg tattccgaca acagattggg
    13861 attggaatat ttatcctcaa gggttatttg atatgttgct tcgtatcaaa gaagaatatc
    13921 ctcaacatcc ggtcatttat ttaactgaaa atggtacagc ccttaaagaa gttaagccag
    13981 agggcgagaa tgatattatt gatgacagta agagaatccg ttatattgag caacatttac
    14041 acaaagtttt agaggctcga gatagaggag tcaatattca aggctatttt atatggtctt
    14101 tgcaagatca attttcttgg gcgaatggct acaataagcg atatggtctt ttctttgttg
    14161 attatgaaac acagaagaga tatattaaga aaagtgctct ttgggtaaaa gggctaaaac
    14221 ggaattaagg ttagcgattt gactgatgtt taatatattt taactatgag cttaaatttt
    14281 ttacaggagg agtttttatg gataagttag tcgctgccat tgaaaagcaa caagggaaat
    14341 ttgaaaaaat ttctactaat aattatatga tagctattaa agatggattt attgctacta
    14401 tgcctttaat tatgttttca agctttttga tgattattat tatgattcct aaaaatttcg
    14461 gagtagagtt accgagtcca gctattgcct ggatgaggaa agtgtatatg ctaaccatgg
    14521 gagttttggg tattattgtt tcagggacag ttgcaaagtc attggctgga aatgttaata
    14581 gaaaaatgcc tcctggaaag gtaataaatg atacttctgc aatgttggcg gccatatgtg
    14641 gctatcttgt attaactgta acgcttgtag ttgatgagaa aacgggatct acaagtttgt
    14701 cgacaaacta tttaggatct caaggattga taacttcgtt tgtcagtgcc tttattactg
    14761 taaatgttta ccgattctgt attaagcgag acattactat tcatttacct aaggaagttc
    14821 ctggggctat atcacaagct tttagagata tttttccttt ttcttttgtt ttacttatta
    14881 gtggtttgtt agatattgta tctcggttta gtttagatgt tccttttgcc caagtatttc
    14941 aacaactatt gactcctatt tttaaggggg cagaatcata tcctgctatg atgttgattt
    15001 ggtttatgtg tgctttgctt tggtttgttg gaattcatgg accatctatt gtcttacctg
    15061 ctgttacagc tttacaactg agcaatatgg aagagaatgc tcaacttctt gcaaatgggc
    15121 agttccctta tcattcttta acacctaatt tcgggaatta tatcgctgct attggaggaa
    15181 cgggggctac ctttgttgta ccatttattt tgattttctt tatgcggtct aaacaattaa
    15241 aatcggtagg taaagctaca attactcctg ttttatttgc ggtaaatgaa cctcttctat
    15301 ttggtatgcc tgttattttg aatccctatc tttttgtccc ttttttgatg actccaccag
    15361 tgaatgtatt tctaggaaag gtatttattg atttctttgg aatgaatgga ttttatatcc
    15421 agttaccttg ggcctttcct ggtcccttgg gattgttaat tggaacgaat tttcaactta
    15481 tctcctttgt atttttatct ttgatgttag ttgtcgacat attgatttat ttgccattct
    15541 gtagagcgta tgatagacag ttactggtga aagaagatat tgcaagctca aatgatatta
    15601 ttttagagga ggatacaagt gaaataatgc ctggtgagat agatgtaata aaaagtaagg
    15661 agttgaaagt actggttctt tgtgcagggt ctggaacaag tgcgcaatta gccaatgcaa
    15721 ttaacgaggg cgctcaatta gcagaagtta gagtgattgc gaattcagga gcgtacggag
    15781 ctcattatga tattatgggt gtttatgatt taattattct ggccccacaa gttcggagtt
    15841 attatagaga gatgaaggtg gatgcagaaa gattagatat tcagatagtt gctaccagag
    15901 gaatggaata tattcattta acaaagagtc caagtaaagc cttacaattt gtattggagc
    15961 attaccaagc tgtgtagtaa gtttttccat cttttatttg agtaaagatt ttgcttacag
    16021 ataggcttgg atttaaaaac gttccccctt ttttaatata agaatccctc tttcacaatt
    16081 gtaaaaagag ggattttgta ttttatctct tagaccaagt tctcttcata aagagaagga
    16141 ggattgggta aatctccaag cgccctgcaa tcattgcaaa ggataggaga atttttgaga
    16201 tgggactaaa gattgagaaa ctagaagtgg ttcctagaat aggcccgata ttattgaaac
    16261 agctaaagac agcgctggtc acgaccagaa aatcattgct atctaggctg acaataaaga
    16321 taagcgctag caaaatcata gcatagatga caaagtactt gagaatctta tgctgggtat
    16381 ctttgtcaat caccgtttta ttaacatgga gggtcaaaac acggtggggc gataggattg
    16441 acaaaatttg gtttttggca atttttgaaa ggatgaggcc tcgaataatc ttgagtccac
    16501 ctgcagttga tccagcagag ccaccgattg ccatgaggaa aaggaggata aactgggaga
    16561 agaggggcca gttggtaata tctccatatc caaaaccagt tgttgtaatg atgttggaaa
    16621 cctggaagaa ggtcatttca aagctctttg aaaaccctgg gtagaggtag agggtgttga
    16681 ggctaatcaa gcctgtagaa accagtacaa tgaccaagta agccctaagc tcttcatctc
    16741 caaagaaggc cttgatgcga cggagcatga ggtagtagta gaggttgaaa tttactccaa
    16801 aaaccagaac tccgatactg accagatagg taatcagtga gctgccatag tgggcaattc
    16861 cgtcgttata gacggtaaag cctccagttc ccgctgtccc catagcaata acaaaactat
    16921 cgtagagagg cataccggct agataataga tgatgacaaa gagggagaag agagctagat
    16981 aaaggagata gagaatctgg gcagtgtttt ttagtttgga tacaaccttg ccaaaaacag
    17041 gacctggaac ctcagccttc atcacctcta ggtggctatt tttggcattg tccataatag
    17101 caagtgcaaa aacaagcact cccatccctc caatcaagtg ggtaaaactt cgccagaaga
    17161 ggagggaacg gctgagaacc gaaacgtcgt tcaaaatact tgctccagta gttgtaaatc
    17221 cagaactaat ttcaaaaaag gcatcaataa ggctggggat ttgcccagaa aagacaaagg
    17281 ggagaccacc aaagaaagac caaaggatcc aacagagggc aacgatcaag actccctcct
    17341 tggcataaat ccgttgattt tttggcttct gtaaactccc tgaaccgcct aacaatacga
    17401 gaatccctat ggtcgaaaag agggctgtaa agacttggct cgattcacgg taatagacag
    17461 caatcgcaac aggaaccaaa agaagaacag cttcaatcaa aagtaatttt gaaaggaggt
    17521 aacgaatcat acttttattc atttcttacc tcgcgatcaa gtcataaatc ttggtgatgt
    17581 ttggcaacaa ggttgttact aggagcttgt ctccaacttc caacatatcc tccccagttg
    17641 ggaaaatagt cttgcccttt cgaataatgg ctgcaataag aacccctttt tttaatttca
    17701 gttgagaaag aggtttggca gtcattttat tggcttcctt gatatggaat tgcagggttt
    17761 cgatttggcc attggctaga tggtgcatgg cttgaaggtc tgaatactgg gcattaactc
    17821 gaccacgaat aaagtgcata atcgtatcta cagcgatgct tttaggtgtg atgatacttg
    17881 aaaaatcagg cgcattgata atctcgagga gactggtacg attgacctta gtaatatttt
    17941 tctgtacacc taccctgtca aggaacatag atgtaatcag attttcctca tcgacacctg
    18001 ttagagtcgc aacggcatca tagtgttgag cactttcttc cagcaggata tcttttgcgg
    18061 ttccatctcc ttgaacgatg tagagatttg ggaatttctc gctaaagaag ctggcgattt
    18121 caggattgat ttcaatgact tttgtatcga tacgactatc tttgagaata ccaagtagat
    18181 aataggcaat tctacctgcc ccaacgatga gaaggctctt cacggcgcgt gatttaaaat
    18241 aattatggaa gagtatcata tcgacacggt taccagtgac aaagattcta tctttatcct
    18301 gtacagtcat gtcaccgctt ggaatgataa tttgatgatc cctctctatc gcacagacaa
    18361 tgacattacc aaatttttta cgaaaatcag aaatgggcat ttggcaaaga ccgctggtgg
    18421 acttgacgac aaattccatg aggctaacgc gtccaccagc aaagcgttcg acagacaggg
    18481 cgttggggaa gtcaatgata ttcgcgatag cgcgggcagc caagagctca ggattaacga
    18541 taagagaaaa accgagaata ttcttttcct tgaaataaga gttagaatat tcagggttcc
    18601 gcacccgaac gatagtttct ttagctccca ttttcttggc tagaactgct gcaatcatgt
    18661 tgacttcatc gtgctcagtc agggcgataa agatatcaca atcttggacg ctggcttgct
    18721 caagaatggc aaaatcggcc ccgttaccaa ggataccaat gatatcaaag cgactgacaa
    18781 tatgattgag aacagcttcg tcttgctcaa tcagcaaaac atcatgcttt tctgcaacca
    18841 aggagcgaca gagggcaaaa ccaacttttc cccctccgac aaggataatt ttcataataa
    18901 aacctacttt ttcatgatgt aactatcata ccctttttca agaaaaaatg cacctactag
    18961 ctaataacca gagtttttag taggaaattt gctataagtt aaaactatac cctaaccaat
    19021 tgaaatagct attagcgact ttctctgaaa tatggtatga taaaggatat acaaggagat
    19081 aaaatgaata ataatttact ggtattacaa tcagactttg gtctggttga tggtgcggta
    19141 tcggctatga ttggagtggc tttagaagag tctccaacct taaaaatcca tcacttgacg
    19201 cacgatatca cgccttataa tatttttgag gggagctatc gtctctttca gacggtggat
    19261 tactggcctg agggaacgac gtttgtatcg gttgtcgatc caggtgtcgg ttcgaaacgt
    19321 aagagtgtag ttgccaagac tgcaaaaaat caatacattg tcacgccaga taatgggacg
    19381 ctttccttta tcaagaaaca cgttggcatt gtagccattc gtgagatttc tgaggtggcc
    19441 aataggcgtc aaaacacaga gcattcttat accttccacg gtcgtgatgt ctatgcctat
    19501 actggtgcta aactggccag tggtcacatt acttttgagg aagtagggcc agagctcagt
    19561 gtggaacaga ttgtagagct tccagtcgta gcgaccatca tagaagatca tctggtgaag
    19621 ggagccattg atattctgga tgtgcgtttc ggttcgcttt ggacctctat cacacgggaa
    19681 gaattttaca agttggaacc agaatttggt gatcgttttg aagtgaccat ctatcatgct
    19741 gatatgctgg tctatcaaaa tcaggttgtc tatggcaaat catttgcaga tgtgagaatt
    19801 gggcaaccca ttctttacat caactctctc tatcgtttag gtttggctat caaccaaggt
    19861 tcctttgcca aggcctataa tgtaggtgtc ggttcatctt ggaccattga aataaagaaa
    19921 atagaaggat aaaataggag aatagtatgg aaatcaaatt tacaattaaa caagttgttg
    19981 ctgtcggaat tggcgctgcc ctctttgtcg tcatcgggat gatcaacatt ccaacccctg
    20041 ttccaaatac aagcatccag cttcagtatg cggtacaagc gctactttct attatttttg
    20101 gaccgattat cggtttgctt gttgggttga ttggtcatgc aatcaaggac tctcttgttg
    20161 gttatggtct atggtggact tggattatcg ctagcggact ctttggttta gttgtgggac
    20221 tttttagaaa gtacgttcgc gtgatcaatg gtgtttttga ctggaaagat attcttattt
    20281 ttaacctcat tcaactactt gcaaatgccc ttgtttgggg tgtcttggca ccacttggag
    20341 atgttgtgat ttatcaagaa gcggcagaaa aagtatttgc acaaggaatt gttgcgggaa
    20401 ttgccaatgg tgtatctgta gctattgcag gaactcttct cttacttgcc tatgcaggaa
    20461 ctcaaactcg tgcaggaagt ttgaaaaagg actaatactc aatgaaaatc aaagagcaaa
    20521 ctaggaagca agtcgcaggt tgctcaaaac agtgttttga ggttgtagat gaaactgacg
    20581 aagtcagtaa ccatacctac ggcaaggcga agctgacgtg gtttgaagag attttcgaag
    20641 agtataaaat gatggggaag gctgggcaac tagtcttttt cgatgtttat agattagtta
    20701 ggcaagtaag ctaggatagg aatctttttg gcgctaagat tttaagagaa gagactgcaa
    20761 gaagggcttg atttatgata aaatagaagt ctaagaagcg aatgaagaga gtaagatgaa
    20821 agaagctata attgagtgga aggatttctc tttccggtat gaaacacaac aagaaccgac
    20881 cttgcaaggg atagacttga ccatttacaa gggagagaaa gtcttaattg ttggaccatc
    20941 tggatcaggt aaatctacct tgggtcagtg tttgaatggg attattccca atatttacaa
    21001 gggtcagaca tatggagaat ttttgataaa gggtcaaaca gcctttgata tgagcatcta
    21061 tgataagtct catctggtta gcacagtttt gcaggataca gatgggcagt ttattggctt
    21121 gtctgtggca gaagatttgg cgtttgctct ggaaaatgat gtgacagccc tagatgagat
    21181 gaaaggtcgt gtttataaat gggctgaaaa gctggacctt cttcctttac tggatcagcg
    21241 ccctcaggat ttgtcaggtg gacaaaagca gcgagtcagt ctggctggtg tcttgattga
    21301 tgaaagtccg attctcttgt ttgatgagcc actcgccaat ctagatccca agtcaggtca
    21361 ggatattatc gaattgattg accagattca taaggaagag gggacgacga ctctgattat
    21421 cgagcaccgt ttggaggacg ttctgcatcg ccctgtggat cggattgtct tgataaacga
    21481 tggtcgtatc ctttttaatg ggagccctga ccagttgctt gcgactgatt tattgactca
    21541 aaatggaatt cgagaacccc tttatctaac gactctccgt caattaggtg tggacttagt
    21601 caaggaagaa caattagcag atctggataa cttgtctatc tcaaaagggc aagtccagtt
    21661 acagacggaa ctggtaaaag aaaccccaga attgcagtca ctctttagac tagaggaagt
    21721 atctttttct tatgatgata gaccgatttt aaaatcccta catttagata ttaaaaaggg
    21781 tgaaaagatt gctattgtcg gaaaaaatgg agcagggaaa tcaactctag ccaaggctat
    21841 aagtagcttt attcagacgg aaggacgcta tctttgggaa aaacaggata taaaaggcga
    21901 ttctgttgca gagcgggcgg aacgagtagg ctatgtgcta caaaatccta atcaaatgat
    21961 ttcaaccaat atgatttttg atgaggtggc tctagggctc cgtttgcgag gtgtggatga
    22021 gaaggaaatt gaaacgagag tctatgaaac cttgaaaatc tgtggacttt atgaattccg
    22081 taattggcct atttctgccc tgtcatttgg tcagaaaaaa cgtgtcacca ttgcttcaat
    22141 tttggtctta ggagctgaaa ttattctcct agatgaaccg actgcaggtc aagatcagaa
    22201 gaactatact gagattatgg aatttctcga agagttacat caaaaagggc ataccattgt
    22261 catgattacc catgatatgc aattgatgct ggattattca gaccgggtcc ttgtcatggt
    22321 ggatggagaa ttgattgccg atactgttcc agccagtctg ttgagcgatc ctgagctgtt
    22381 agtaaaagcc aatctaaaag aaacctccat ctttaacttg gctaagaaac tagatgtgga
    22441 tccactggat ttaacggcat tttacaaaga aaggagagag ggatgcaagc taaattaatc
    22501 ggttaccagc atagagatac tgtgattcat cgcttgtcag gagctgggaa acttctcttt
    22561 ttcattctgg tatcattggc ggccatgatt agctatgata ccagaatgct cttgctgatt
    22621 gccatctttt cagtctttct cctctattta tcagaaattc gctttaaaga tgtttccttt
    22681 gtagccgttt ttgcgacggt atttgccgtt ttaaacgttt tgatggtcta tctcttttct
    22741 cccgagtatg gggttggact ttatggagag agaagtgtga tttggcaggg aatcggtgtc
    22801 tacactctaa ccagccagga gctcttttat ctgctaaatt tggccattaa gtatctttgc
    22861 accattcctc tggctattat ctttttgatg acaacccatc ctagtcagtt tgcttccagt
    22921 ttaaatcaaa ttggtgtgcc ctataagatt gcttattctg tcagcctgac cttgcgctat
    22981 attccagatt tgcaggaaga attctttact atcaagatgt ctcaggaggc gcgtgggatg
    23041 gaattatcca agaaagcttc tcttatgcaa cgaatcaaag gcaatctgct cattattacg
    23101 cccttgattt ttagctcgct agaacgcatt gataccattg cgactgccat ggagcttcgc
    23161 cgctttggga aagagaaaaa acgcacatgg tatagttatc aggccttgaa aaaaggagac
    23221 tatattacct tgctcttggc aaccttgttt ttagtagtta gtttactact tatcttgcag
    23281 aatcagggac gattttacaa cccttggaaa tagcttgaaa aaattgaaaa aatcaagtcg
    23341 tttctattga caatgattct gaaagtgtta tactaagaaa gtagtttcgc tgatttactt
    23401 caaacctgtt gtgaggtaag ttaacgatgc cttaaccacg ctgtttgctg agcttgactc
    23461 cgggcagtgt ggctattttt ttgcaatggt gaaaggaagc aagtcatgac aaatcacatt
    23521 gtattatttg aacctcaaat tccacaaaat acgggcaata tcgcgcgtac ttgcgctgcg
    23581 accaattctc ccctccacat catcaagcct atgggctttc ctattgatga ccgcaagatg
    23641 aagcgggctg gattggatta ctgggataag ctagagattt atttttacga gagtttggaa
    23701 gatttcatat ctcagatgaa gggaaaactc tatctgattt cgaaattcgc ggaaaaagtc
    23761 tattctgagg tggatttatc gactgacgag gaccattatt ttctctttgg acgtgaagac
    23821 aagggcttac ctgaagattt tatgcgagaa catcctgaga aggctctccg tattcccatg
    23881 aatgatgaac atgtccgcag tctcaatgtg tctaataccg tctgcatgat tgtctatgag
    23941 gctcttcgcc agcagaactt tgcaggtctt gagctcgtcc atacctatga agtggataaa
    24001 ttgaaataaa aaatgaaaat gaacaaaatg cttgcgcttg caagcgtttt ttgttatgat
    24061 aaaagagtct tcagggcagg gtgtgattcc cgaccggcgg tgactttaac taggaaatga
    24121 tcttttcctt ttatactttg ttgacaagct ttgcctaacc agaagttatg cctacagctt
    24181 gtcgcctagt ctaaaagaaa aatctctatt tccttctctt taaagaagtc cgcgagcgca
    24241 agctgatgtg gtgagattcc acaaccgaca gtatagtctg gatgggagaa gacgaaagaa
    24301 tagctttgtc tgttttgata gatttatagc cggattgtaa ccacttgctt tgtttttctt
    24361 taatagagta agagggaact tttgggatat aaaaagtgag aatagataga ggaatccttt
    24421 ccaacttctt ctgattttat agaaaattgg aggaacctgt tatgacaaat acacgtcgac
    24481 tttcgaccat tgcaatttta tcagccatct catttgtgct gatgtacttt gactttccgc
    24541 ttttaccagc ggcatctttc ctcaagatcg aatttagtat cttgccagtc cttgtgggtc
    24601 tggtggtcat ggatttgcct gctgctctag gagtgctctt gcttcgctca ctcttgaaat
    24661 tgcttcttaa cagccaagga gtgaatactt acattggttt gccgatgaat atcgtagctt
    24721 tgggagtttt tgtcatcgta tttgctttga tttggaaaaa ggaacggaca acccttcgtt
    24781 tcctactagg ctctctagct ggaactgttg gtttaacctt ggccatgttg gttctcaact
    24841 atgtttatgc tgttcctttg tacgctaagt ttgctaactt tgatattgga aaaattttgg
    24901 gactttccaa ctacctaatg accatggtat taccttttaa cttgattgag ggtgtaatct
    24961 tttccgtttc attctggttg ttgtacgtcc ttttgaaacc aaccttaaaa cactatgaaa
    25021 gataaacaaa catttttaat gaagggcagt tttgcccttt tacttttcgt tattcttggc
    25081 tatatggtca aattttaccc tgaaatgttg gtcaattttg accaatcgat tcagactgcc
    25141 attcgaggag acttaccaga ttatttgact attctttttc gagccctcac acgtctgatt
    25201 gatatcccag tgattatcac ttgggttgtc attacagctt ttgtctttta tcgtaagcga
    25261 tggaagatag aaagtttctt catgctggga aatctggctt tggcaggtct tttaatcgtg
    25321 acctttaaaa atatctacca gcgcccacga ccagctatct tacatctggt ggaagagaag
    25381 ggattttcct tcccaagtgg gcattctctg gctgtaactt tgatggtagg tactctgatt
    25441 gtcattctca gtcaacgaat taaaaatcca gtctggagaa aaatcgtaca aatcgtcctt
    25501 ggcctctacc tagtcagtgt gctggtatca agagtctatc tgggagttca ttacccatca
    25561 gacgtccttg ccagtctctg tgtgggcttg ggagtcctgt ttatcgagtt tcccttctat
    25621 gacaagctcc gcttccaatg gcgatttaaa ggcaaacaga agtgagtatc gaattccctt
    25681 gaggagaaag aaatgaaagt caatatagca gatcttcatc tgactcaact atatttatca
    25741 gaaaagaagt tgcaagatat tcagatgctt taccagtcgg cagaaacaat ccaagtcgat
    25801 ccaatcagta ttcttgcctt tggagattgt ttgctgatta cagatgggca tcacagggct
    25861 tatcaggctt tattggcagg tcgggatacg atttctgctg agtgggatag agatggtggt
    25921 gatgaactat atcatctcta tgcgcaagct tgcgaggaaa gaaagattta ctctgttttt
    25981 gatttagaag atcgtatcct agctcaagat gggtatgaag caaaatggta taactggtgt
    26041 gatggtttta atcaagcagc aactcttttg ttgaaaaggt agtgcattgt gttttgttcc
    26101 ttattataag gtcaatcatt gtgaggaagc ttttgcttgg tatcaggatg tgaacttggt
    26161 ttacctcgta gatggggtga agcttcctta cagtcaagcg accttggaag ccatgtattc
    26221 ctatttggat cggcatggtg agcttttttg gattgaagtc aaggagaagg gagaatggtt
    26281 tccaattggg gatattacac tatctcagga taatctcccc attgtgattg ggaattccgc
    26341 ttaccaacat cgaggacttg gaaaaaagat tctaagtgct ttgattgaat tggctcgagt
    26401 aaaaggatgg aaagaattga gagtcaagaa aatctacacc tacaatcatg cttctaggag
    26461 gtgtttcaag tcgcttggat ttgtggaaaa tggagcaaca gaaaaaggaa tgagttttat
    26521 attggaatta gtctaatcct gccactttct cccccttaac ctttgactat tccgcaaaat
    26581 tatcgtaaaa taaagagtga atgataaaat gaggtcagag tctgttcgct ctggcgatag
    26641 tagtataaat gaggagaaac gctttgaaat tagaagtatt tgctgggcaa gaaaaaagtg
    26701 aactatctat gattgaggta gcgcgtgcta tcttggaact tcgtggtcgc gatcatgaga
    26761 tgcattttag cgatcttgta aacgaaattc aaaactacct tggaacatca aacagcgata
    26821 tccgcgaagc tttgcctttg ttctacacag agttgaactt tgacggtagc ttcatctcac
    26881 ttggggacaa caaatggggt cttcgttcat ggtatggtgt ggacgaaatc gacgaagaaa
    26941 tcatcgctct tgaagaaaat gacgacgatg aagtaacacc aaaagctaag aaaaaacgtg
    27001 tcaatgcctt tatggatggt gattcagatg ccattgacta caatgcagat gatccagaag
    27061 acgaagatgc atacgaagca gatccagctc tttcatacga tgatgaaaat ccagatgatg
    27121 aaaaaaatga agtggaagct tatgatgcag aaatcaacga aatcgctcca gatgacttgg
    27181 gagaagatgt ggatctcaac gaagacgacg acgagttttc agacgacgac gctgaaacca
    27241 gcgaggaata agagttagct attgacaatt atcctatttt taggtatcat attgtttggg
    27301 cacctctttt agaggtcggg gctccctagt tcttagggag ctatttttgt tttttcaaga
    27361 agttatcttc ttgtatttta tactcaatga aaatcaaaga gcaagctagg aaactagccg
    27421 taggctgctc aaaacactgt tttgaggttg tagataagac tgacaaagtc aggaacacat
    27481 atctacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta ttagttgtga
    27541 atctggtgca gtcgtcccag attattctta ttagtagggt cttgttttct atatcccctc
    27601 gtagttaaca agaccttgag cattttagaa agaggaatct atgtctacga aatatatttt
    27661 tgtaactggt ggtgtggtat cgtccattgg gaaagggatt gtggcagcga gtctaggccg
    27721 tctcttgaaa aatcgtggtc tcaaagtaac cattcaaaag tttgaccctt atatcaatat
    27781 tgatccggga accatgagtc cttaccagca cggggaagtt tttgtgacag atgacggagc
    27841 tgagacagat ttggacttgg gtcactatga acgtttcatc gatatcaatc tcaacaaata
    27901 ttccaacgtg acaactggga aaatttacag tgaagttctt cgtaaagaac gccgtggaga
    27961 ataccttggg gcaactgttc aagtcattcc tcatatcaca gatgctttga aagaaaaaat
    28021 caagcgtgcc gctctaacga ccgactctga tgtcattatc acagaggttg gtggaacagt
    28081 aggagatatc gagtccttgc cattcctaga ggctcttcgt cagatgaagg cagatgtggg
    28141 tgcggataat gtcatgtata tccatacaac cttgcttcct tacctcaagg ctgctggtga
    28201 aatgaaaacc aaaccaaccc aacactctgt caaagaattg cgtggcttgg gaatccaacc
    28261 aaatatgttg gttattcgta cagaagagcc agctggtcaa ggaattaaaa ataaactggc
    28321 ccagttctgt gatgtggcac cagaagccgt tatcgaatcg ttggatgttg aacaccttta
    28381 ccaaattcca ctgaacttgc aggcacaagg gatggaccaa attgtttgtg atcatttgaa
    28441 attagacgca ccagcagcgg atatgacaga atggtcagcc atggtggaca aggtcatgaa
    28501 cctcaagaaa caagttaaga tttcccttgt tggtaagtat gtggagttgc aagatgccta
    28561 tatctcagtg gtcgaagcct tgaaacactc tggctatgtc aatgatgtag aagtcaaaat
    28621 caattgggtc aatgccaatg atgtgacagc agagaatgta gcagaactct tgtctgatgc
    28681 ggacgggatc atcgtaccag gtggttttgg tcaacgtggt acagaaggga aaatccaagc
    28741 catccgctat gcgcgtgaaa atgatgttcc aatgttggga gtctgcttgg gaatgcagtt
    28801 gacatgtatc gagtttgctc gtcacgtttt aggtcttgaa ggtgccaatt ctgcagagct
    28861 tgcaccagaa acaaaatacc ctatcattga tatcatgcgt gatcagattg atattgagga
    28921 tatgggtgga acccttcgtt tgggacttta tccgtctaag ttgaaacgtg gctctaaggc
    28981 tgctgctgct tatcacaatc aagaagtggt gcaacgccgt caccgtcacc gttatgagtt
    29041 taataatgcc ttccgtgagc agtttgaggc agcaggtttt gtcttttcag gagtttctcc
    29101 agacaatcgt ttggtagaaa tcgtggaaat tcctgaaaat aaattctttg tagcttgtca
    29161 gtatcaccct gaactgtcaa gccgtccaaa ccgaccagaa gaactctaca ctgcctttgt
    29221 tactgcagcg gttgagaaca gcaattagca aaatcagaac ctttgagaaa aatctcagag
    29281 gttttttgca tacgatgata ttgcagtata tctgaggtag gggtcctctg tatgtacctg
    29341 ctaccgttga aatcaatagc gactccctct tgccctgtgc tagtgaatgg atttatcagt
    29401 atattgaaat gaaataaaat ttgaacaaat taattcggaa agccaaatca atttctagca
    29461 aagttttagg aactggattg tatagtgaat tgaaataaga tgtgaacatc tctatcagaa
    29521 aagtcaaatt aatttataga aatattttag cagtcaagat gtactgttat agattcaata
    29581 cattatactt ttttaattta atcca
//
LOCUS       DBEJZJ010000023        29369 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000023 DBEJZJ010000000
VERSION     DBEJZJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.23"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            184..414
                     /gene="blpU"
                     /locus_tag="ACL3R8_001328"
                     /pseudo
     CDS             184..414
                     /gene="blpU"
                     /locus_tag="ACL3R8_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            417..542
                     /locus_tag="ACL3R8_001329"
     CDS             417..542
                     /locus_tag="ACL3R8_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR1314199.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1129..3282
                     /gene="comA"
                     /locus_tag="ACL3R8_001330"
     CDS             1129..3282
                     /gene="comA"
                     /locus_tag="ACL3R8_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR1314200.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3295..4644
                     /gene="comB"
                     /locus_tag="ACL3R8_001331"
     CDS             3295..4644
                     /gene="comB"
                     /locus_tag="ACL3R8_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR1314201.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKEDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4814..5521
                     /gene="purC"
                     /locus_tag="ACL3R8_001332"
     CDS             4814..5521
                     /gene="purC"
                     /locus_tag="ACL3R8_001332"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR1314202.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5578..9303
                     /locus_tag="ACL3R8_001333"
     CDS             5578..9303
                     /locus_tag="ACL3R8_001333"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR1314203.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEVANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9396..10838
                     /gene="purF"
                     /locus_tag="ACL3R8_001334"
     CDS             9396..10838
                     /gene="purF"
                     /locus_tag="ACL3R8_001334"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR1314204.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGKLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEDRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10875..11897
                     /gene="purM"
                     /locus_tag="ACL3R8_001335"
     CDS             10875..11897
                     /gene="purM"
                     /locus_tag="ACL3R8_001335"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR1314205.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11894..12439
                     /gene="purN"
                     /locus_tag="ACL3R8_001336"
     CDS             11894..12439
                     /gene="purN"
                     /locus_tag="ACL3R8_001336"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR1314206.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12523..13032
                     /locus_tag="ACL3R8_001337"
     CDS             12523..13032
                     /locus_tag="ACL3R8_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR1314207.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13057..14604
                     /gene="purH"
                     /locus_tag="ACL3R8_001338"
     CDS             13057..14604
                     /gene="purH"
                     /locus_tag="ACL3R8_001338"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR1314208.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDMTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADNIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14726..15988
                     /gene="purD"
                     /locus_tag="ACL3R8_001339"
     CDS             14726..15988
                     /gene="purD"
                     /locus_tag="ACL3R8_001339"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR1314209.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            16245..16361
                     /locus_tag="ACL3R8_001340"
     CDS             16245..16361
                     /locus_tag="ACL3R8_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR1314210.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16391..16879
                     /gene="purE"
                     /locus_tag="ACL3R8_001341"
     CDS             16391..16879
                     /gene="purE"
                     /locus_tag="ACL3R8_001341"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR1314211.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16866..17957
                     /gene="purK"
                     /locus_tag="ACL3R8_001342"
     CDS             16866..17957
                     /gene="purK"
                     /locus_tag="ACL3R8_001342"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR1314212.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17967..18194
                     /locus_tag="ACL3R8_001343"
     CDS             17967..18194
                     /locus_tag="ACL3R8_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR1314213.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVKAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18257..19555
                     /gene="purB"
                     /locus_tag="ACL3R8_001344"
     CDS             18257..19555
                     /gene="purB"
                     /locus_tag="ACL3R8_001344"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR1314214.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19610..23548)
                     /gene="strH"
                     /locus_tag="ACL3R8_001345"
     CDS             complement(19610..23548)
                     /gene="strH"
                     /locus_tag="ACL3R8_001345"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR1314215.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23863..24579)
                     /locus_tag="ACL3R8_001346"
     CDS             complement(23863..24579)
                     /locus_tag="ACL3R8_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1314216.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24927..26714
                     /locus_tag="ACL3R8_001347"
     CDS             24927..26714
                     /locus_tag="ACL3R8_001347"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR1314217.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26711..27187
                     /locus_tag="ACL3R8_001348"
     CDS             26711..27187
                     /locus_tag="ACL3R8_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1314218.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27215..28120
                     /locus_tag="ACL3R8_001349"
     CDS             27215..28120
                     /locus_tag="ACL3R8_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR1314219.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28107..28922
                     /locus_tag="ACL3R8_001350"
     CDS             28107..28922
                     /locus_tag="ACL3R8_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR1314220.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28929..29333
                     /locus_tag="ACL3R8_001351"
     CDS             28929..29333
                     /locus_tag="ACL3R8_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1314221.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
BASE COUNT         8075 a         5727 c         6924 g         8643 t
ORIGIN      
        1 gtaaaaaagt gattagaaaa catctttttt aaaaatagag atgattttga aacaaaaaag
       61 ctaattcaag acgtttcgat gccaattcaa gatttggatg aaaaaaatta atagatactg
      121 ttatactaaa cttgtcaagt ttgtaacaag acaaatatta aaaataaaaa agaggtattc
      181 gttatgaata caaaaaagat gtcacaattt gaaattatgg atactgagat gcttgcttga
      241 gttgaaggtg gcggatgcaa ttggggagat tttgccaaag caggtgttgg aggaggagta
      301 gcacgaggtc ttcagctagg aattaaaaca agaacatggc aaggtgcagc aactggtgct
      361 gcgggaggag ctatacttgg aggtgtggcc tatgaagcga catgttggtg gtaattatgg
      421 attttaaaag ttttattatt ggtttagtag ttggtatatt tggtccttat atggatgatt
      481 taattagaaa aaaattttta aagtcttcgg agaagaaaac agaaaaatct gttaaaaaat
      541 aatcaaaact ataaatgatg aatctgaatc aaaattattt tgcgcatgta aagaggagtc
      601 ttatagtaac gagtcaaaaa aggagtaact atgaatcgta atttagaacg gtgttatcta
      661 ttctgactag ggatagatca taccataggt agcttagaaa tagcagagac attagaaatt
      721 gaagtaataa ataggatgtc gtaagtgtta ctatcaatga tttatttgtt tcaagcttgc
      781 ctagggtgtc agtaaaaaat cattttcctt tcaatagcat atttttagtg ggcaggactc
      841 ttgttctgcc tattttttta tccaaaaagt gcagttggga gggagatagg ctcatttggg
      901 aaggaagtcc agtttttgtt tagtgattgg ggtaagatag ttgttatcag atgagtttat
      961 attcttcgaa aatcaaattc aaaccacgtc aacgtcgcct tgccgtatat atgtgactga
     1021 cttcgtcagt cctatctaca acctcaaaac agtgttttga gcagcctgcg gctagtttcc
     1081 tagtttgctc tttgattttc attgagtatt agggaaaagg agatgaatat gaaatttggg
     1141 aaacgtcact atcgtccgca agtggatcag atggactgcg gtgtagcttc attagccatg
     1201 gtttttggct actatggtag ttattatttt ttggctcact tgcgagaatt ggctaagacg
     1261 accatggatg gaacgacggc tttgggcttg gtcaaggtgg cagaggagat tggttttgag
     1321 acgcgagcca ttaaggcgga tatgacgctt tttgacttgc cggatttgac ttttcctttt
     1381 gttgcccatg tgcttaagga agggaaattg ctccactact atgtggtgac tgggcaggat
     1441 aaggatagca ttcatattgc cgatccagat cccggggtga agttgaccaa actgccacgt
     1501 gagcgttttg cggaagaatg gacaggagtg actcttttta tggcacctag tccagactac
     1561 aagcctcata aggaacaaaa aaatggtctg ttctctttta tccctatatt agtgaagcag
     1621 cgtggcttga ttgccaatat cgttttggca acactcttgg taaccgtgat taacattgtg
     1681 ggttcttatt atctgcagtc tatcattgat acctatgtgc cagatcagat gcgttcgaca
     1741 ctagggatta tttctattgg gctagtcatc gtctacatcc tccagcaaat cttgtcttac
     1801 gctcaggagt atctcttgct tgttttgggg caacgcttgt cgattgacgt gattttgtcc
     1861 tatatcaagc atgtttttca cctccctatg tccttctttg cgacacgcag gacaggggaa
     1921 atcgtgtctc gttttacaga tgctaacagt atcatcgatg cgctggcttc gaccatcctt
     1981 tcgattttcc tagatgtgtc aacggttgtc attatttccc ttgttctatt ttcacaaaat
     2041 accaatctct ttttcatgac tttattggcg cttcctatct acacagtgat tatctttgcc
     2101 tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg aagccaatgc ggttctatct
     2161 tcttctatca ttgaggacat caacggtatt gagactatca agtccttgac cagtgaaagt
     2221 cagcgttacc aaaaaattga caaggaattt gtggattatc tgaagaaatc ctttacctat
     2281 agtcgagcag agagtcagca aaaggctctg aaaaaggttg cccatctctt gcttaatgtc
     2341 ggcattctct ggatgggggc tgttctggtc atggatggca agatgagttt ggggcagttg
     2401 attacctata ataccttgct ggtttacttt accaatcctt tggaaaatat catcaatctg
     2461 caaaccaagc ttcagacagc gcaggttgcc aataaccgtc taaatgaagt gtatctagta
     2521 gcttctgagt ttgaggagaa gaaaacagtt gaggatttga gcttgatgaa gggagatatg
     2581 accttcaagc aggttcatta caagtatggc tatggtcgag acgtcttgtc ggatatcaat
     2641 ttaaccgttc cccaagggtc taaggtggct tttgtgggga tttcagggtc aggtaagacg
     2701 actttggcca agatgatggt taatttttac gacccaagtc aaggggagat tagtctgggt
     2761 agtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc agtacataaa ctatctgcct
     2821 caacagccct atgtctttaa cggaacgatt ttggagaatc ttcttttggg agccaaggag
     2881 gggacgacac aggaagatat cttacgggcg gtcgaattgg cagagattcg agaggatatc
     2941 gagcgcatgc cactgaatta tcagacagaa ttgacttcgg atggggcagg gatttcaggt
     3001 ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga cagatgcgcc ggtcttgatt
     3061 ttggatgagg cgactagcag tttggatatt ttgacagaga agcggattgt cgataatctc
     3121 atggctttgg acaagacctt gattttcatt gctcaccgct tgactattgc tgagcggaca
     3181 gagaaggtgg ttgtcttgga tcagggcaag attgtcgaag aaggaaagca tgctgatttg
     3241 cttgcacagg gtggctttta cgcccatttg gtcaatagct agaaagagga gaggatgaaa
     3301 ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt accataattt ttccagtagt
     3361 gtgattgtac ccatggccct tctgctcgtg tttttacttg gctttgcaac tgttgcagaa
     3421 aaggagatga gcttgtccac tagagctact gtcgaaccta gtcgtatcct tgcaaatatc
     3481 cagtcaacta gcaacaatcg tattcttgtc aatcatttgg aagaaaataa gctggttaag
     3541 aaggaggatc ttttggttca ataccaagaa ggggcagagg gtgtccaagc ggagtcctat
     3601 gccagtcagt tggacatgct aaaggatcaa aaaaagcaat tggagtatct gcaaaagagc
     3661 ctgcaagaag gggagaacca ctttccagag gaggataagt ttggctacca agccaccttt
     3721 cgcgactaca tcagtcaagc aggcagtctt agggctagta catcgcaaca aaatgagacc
     3781 atcgcgtccc agaatgcagc agctagccaa acccaagccg aaatcggcaa cctcatcaat
     3841 caaacagagg ctaaaattcg cgattaccag acagctaagt cagctatgga aacaggtgct
     3901 tccttggcca gtcagaatct agcctactct ctttaccagt cctacaagtc tcagggcgag
     3961 gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg aagcacagat ttctcagtta
     4021 gaatctagtc ttgctactta ccgtgtccag tatgcaggtt caggtaccca gcaagcctat
     4081 gcgtcagggt taagcagtca attggaatcc cttaaatccc aacacttggc aaaggttggt
     4141 caggaattga cccttctagc ccagaaaatc ttggaggcag agtcaggtaa gaaggtacag
     4201 ggaaatcttt tagacaaggg gaaaattacg gcaagtgagg atggggtgct tcatcttaat
     4261 cctgagacca gtgattctag catggttgca gaaggtgccc tactagccca actttatcca
     4321 tctttggaaa gagaagggaa agccaaactc acagcctatc taagttcaaa agatgtagca
     4381 agaatcaagg tcggtgattc tgttcgctat actacgactc atgatgccgg gaatcaactt
     4441 tttctagatt ctactattac aagtattgat gcgacagcta ctaagactga gaaagggaat
     4501 ttctttaaaa tcgaggcgga gactaatcta acttcggagc aggctgaaaa acttaggtac
     4561 ggggtggaag gccgtctaca gatgattacg ggcaagaaaa gttacctacg ttattatttg
     4621 gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga gttaaataat ttttaaactg
     4681 tgagaaagat tcttcttgca gttttttctt tacaattttt gaaaaacatc tgctatttat
     4741 tcggttgaat tcttgtgttt tttggttttt tgtggtaaaa tgtgctcaag taatacgaaa
     4801 ggcgaacttt aaaatgtcaa aacaattgat ctattcggga aaagctaaag atatctatac
     4861 aactgaggat gaaaatctta ttatttcaac ttacaaggac caggcgactg ctttcaacgg
     4921 tgtcaagaag gagcagattg caggtaaggg agtcttgaat aatcagattt catcttttat
     4981 ttttgagaaa ttaaatgcgg ctggtgtggc gactcacttt gtggagaaac tttcagacac
     5041 ggaacaactc aataaaaagg ttaagattat tcctttggaa gtcgtgctcc gcaactatac
     5101 tgctggttcc ttttcaaaac gttttggtgt ggatgaggga atcgccttgg agactccgat
     5161 tgtcgaattt tactacaaaa atgatgattt ggatgatcca tttatcaatg atgagcatgt
     5221 gaaattccta cagattgcgg gtgaccagca gattgcctac ttgaaggaag aaacgcgtcg
     5281 tatcaatgaa ctattgaaag tctggtttgc tgagattggg cttaaattga ttgactttaa
     5341 gctagagttc ggttttgaca aggatggcaa gattatcttg gcagacgaat tttcaccaga
     5401 taactgccgc ttgtgggacg ctgatggcaa ccacatggat aaggatgttt tccgtagagg
     5461 attgggagaa ctaaccgacg tttatgagat tgtttgggaa aagttgcagg gtttaaaata
     5521 acaacctcaa ggctgtttgg gaatattgca agagctgaaa taaaggaata agaattgatg
     5581 gataaacgta tttttgttga aaaaaaggct gattttcagg tcaagtcaga gagtttggtt
     5641 agagagctcc agcacaacgt gggactgtca agcttgaaaa gtattcgtat tgtgcaagta
     5701 tatgatgtat ttgacttggc tgaggacttg tttgcacctg cagagaagca cattttctct
     5761 gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc aggcggatct tgctaactat
     5821 gctttctttg ccattgaaag tctgccaggg cagtttgacc agcgtgcagc ttcgtcacag
     5881 gaagccttgc ttttgttggg aagttcgagt gacgtgacag tcaacacagc ccaactttac
     5941 ttggtgaata aagatattga tgcgactgag ttggaagctg tcaaaaacta cctgctcaat
     6001 ccagttgatt ctcgtttcaa ggatatcacg acagggattg ccaagcagga gttttcagag
     6061 tcagacaaga ccattccaaa attgactttc tttgaaagct atacagcaga agactttgct
     6121 cgctacaagg ccgagcaagg gatggccatg gaagtggatg atttgctctt tatccaagac
     6181 tactttaagt caatcgggcg cgtgccaact gagactgaac tcaaggtttt ggacacttac
     6241 tggtctgacc actgccgtca tacgactttt gagacagagt tgaaacacat cgacttttca
     6301 gcttctaaat ttcaaaagca attgcagtca acctatgaca agtatattgc catgcgcgag
     6361 gagttaggtc ggtctgaaaa accacaaacc ttgatggata tggcgactat tttcggtcgt
     6421 tatgagcgtg ctaacggacg attggatgat atggaagtct ctgacgaaat caatgcctgc
     6481 tcagttgaaa ttgaagtgga tgttgatggt gtcaaggaac cttggctcct catgtttaaa
     6541 aatgaaaccc acaaccatcc aacagaaatt gagccatttg gtggagcggc tacctgtatc
     6601 ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg tttaccaagc catgcgtatt
     6661 tcaggtgctg gtgatattac agcaccgatt tcggaaactc gtgctgggaa attgccacaa
     6721 caagtcattt ctaaaacagc agctcatggt tattcttcat atggtaacca gattgggctt
     6781 gccacaacct acgttcgtga atacttccac ccaggctttg tagctaaacg tatggaactt
     6841 ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc gtgaaaaacc tgaagcaggt
     6901 gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg gtgtcggtgg tgcgacgggc
     6961 tcttctaagg ttcaaacagt tgagtctgta gagactgctg gtgctgaggt tcaaaaagga
     7021 aatgccatcg aagaacgcaa gattcagcgc ctcttccgta atggcaatgt cactcgtctg
     7081 atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg tggctatcgg tgaattggca
     7141 gacggtcttg aaatcgacct caacaaggtg cctcttaaat accagggctt gaatggtaca
     7201 gaaattgcca tctctgaatc acaagaacgg atggcggtcg tggttcgtcc tgaagatgtg
     7261 gatgccttcg ttgccgaatg taacaaagaa aatattgatg ctgttgtggt ggcgatagta
     7321 actgaaaaac caaatcttgt catgcactgg aatggtgaga caatcgttga cttggagcgt
     7381 cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg ccaaagttgt ggacaaggat
     7441 gtcaaactcc cagaagagcg tcaaacatct gctgaaacac tggaatcaga tacccttacg
     7501 gttctatctg acctcaacca tgcaagtcaa aaaggattac agactatctt tgactgctct
     7561 gttggacgct caacggttaa tcacccactt ggtggtcgtt accaactcac accaactgag
     7621 gcatctgtgc agaaattgcc agttcaacac ggtgtgactc atactgcgtc ggtcattgct
     7681 caaggtttca acccatatgt agctgaatgg tctccatacc acggtgctgc ttatgcggtt
     7741 atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact ggtccaaggc tcgtttctct
     7801 taccaagagt atttcgagcg tatggataaa caagcagagc gtttcggtca gccagtagct
     7861 gctcttctag gttctattga agcacaaatt cagcttggct tgccatctat cggtggtaag
     7921 gactccatgt ctggtacctt tgaagaattg accgttccgc caaccttggt tgcctttggg
     7981 gtgacgacgg cagatagccg taaggtgctc tctccagaat ttaaagctgt tggggaaaat
     8041 atctactaca tcccaggtca agccctctct gcagagattg attttgactt gattaagaaa
     8101 aattttgctc agtttgaagc catccaagct gaccataaag tgacatctgc atcagctgtc
     8161 aaatacggtg gtgtagttga aagtttggct cttgctacct ttggaaacta tattggtgca
     8221 gaggtgacct tgcctgaact tgaaacagct ttgacagctc aattaggcgg ctttgtcttc
     8281 acatctcctg aagaaattgc tggagtagag aaggttggac aaacgaaagc agactttaca
     8341 ctgactgtca acggtgtgaa gctagatgga cacaagcttg acagtgcatt tcaagggaca
     8401 ttggaagaag tttacccaac agaatttacc caagcgaaag aactagaaga agtaccagct
     8461 gtggcatcag atgttgtgat taaagccaaa gaaaaggttg aaaaacctgt ggtttacatc
     8521 ccagtctttc caggaaccaa ctcagaatat gattcagcta aggccttcga aaaagaaggt
     8581 gcagaggtca atttggtgcc attcgtgacc ttgaatgaag aagctattgt caagtcagtt
     8641 gaaactatgg ttgacaatat cgacaagact aatattctct tctttgctgg tggattctcg
     8701 gctgcggatg aaccagatgg ttcagctaag tttatcgtca atatcctgct taatgaaaaa
     8761 gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggtt tgattatcgg tatttgtaat
     8821 ggattccaag ccttagtcaa atcgggtctc ctaccctacg gaaactttga agttgctaac
     8881 agtactagcc caaccctctt ctacaatgat gccaaccaac acgtggccaa gatggtggaa
     8941 actcgcattg ccaataccaa ctcaccatgg ttggctggtg tgcaagtggg cgatatccac
     9001 gctattcctg tttcgcacgg tgaagggaag tttgtcgtga cggctgagga atttgcagag
     9061 ctccgtgaca atggacaaat tttcagccaa tacgttgact ttaacggtaa accaagtatg
     9121 gattctaagt acaatccgaa tggttctgtc catgccatcg aaggaattac cagcaagaat
     9181 ggtcaaatca tcggtaagat gggccactca gaacgttatg aggacggtct tttccaaaat
     9241 atcccaggca ataaagacca gcacctgttc gcgtcagcgg ttaaacattt cactggaaaa
     9301 taagacttac agattttcta atagatagta tcagtaatgt aaaagtcatg taaatctagc
     9361 tcttgatgat tacaaatgaa aattaggtat aaaaaatgac atacgaagta aaatctctta
     9421 atgaagaatg tggtgttttc ggtatttggg gacatccaga tgctgctaag ttgacctatt
     9481 ttggactcca cagtcttcag caccgtggtc aagagggggc aggaatcctc tccaatgacc
     9541 aaggaaaact aaagcgccat cgtgacatgg gacttttatc agaagtcttc agaaatcctg
     9601 ctaatttgga taaattgaca gggactggtg cgattgggca tgtgcgttat gcgactgctg
     9661 gcgaagcttc tgtagataac atccagccct tcctcttccg ttttcacgat atgcagtttg
     9721 gcttggctca taatgggaat ctgaccaatg cagcctctct caagaaagaa ttggaagata
     9781 gaggagcaat tttcagtgcg acttcggatt cggaaatctt ggctcatctc attcgtcgca
     9841 gtcataatcc tagcctgatg ggcaaaatca aggaagcgct cagccttgtc aaaggtggtt
     9901 ttgcctatat cttgctgttt gaggacaagt tgattgcggc tcttgacccc aatggtttcc
     9961 gtccgctttc tatcgggaaa atggctaatg gagcagttgt tgtatcttct gaaacctgtg
    10021 cttttgaggt tattggtgcc gagtggattc gtgatttgaa gccaggtgag attgtgatca
    10081 ttgatgacga gggcattcag tatgacagct atacagatga tacccagttg gcgatttgtt
    10141 ctatggagta tatctacttt gctcgccctg attctaatat ccacggtgtc aatgtccata
    10201 cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt taagcatgag gcagatattg
    10261 tagttggtgt gcccaattct tccctaagcg cggctatggg atttgcggaa gaatcaggct
    10321 taccaaatga aatgggtctg atcaaaaacc aatacaccca gcgaactttt atccaaccga
    10381 ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc tgctgtttcg ggtgttgtca
    10441 aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg tggaacaacc tctcgtcgta
    10501 tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca cgttgccatt ggaagtcctg
    10561 cactagcgta tccatgtttc tacgggattg atatccagac ccgtcaggag ctgattgcag
    10621 ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc ggacagtatg acttatcttt
    10681 caattgatgg cttgattgag tcgattggta tcgaaacaga tgcgccgaac ggtggtctct
    10741 gtgtcgctta ctttgacggt gactacccaa cgcctctcta tgactacgaa gaagactatc
    10801 gtagaagttt ggaagaaaag accagttttt acaagtaggc gacagattct ccattaaaga
    10861 aaaggaaaaa acaaatgaca aataaaaatg catatgccca gtcgggtgtg gatgttgaag
    10921 cgggttatga agttgttgaa cggattaaaa agcacgtggc ccgtacggag cgtgcaggtg
    10981 tcatgggagc tcttggtggc tttggtggta tgtttgacct ttccaagact ggggttaaag
    11041 aacccgtctt gatttcaggg actgacggtg tcggaaccaa gctcatgttg gctatcaagt
    11101 acgacaagca cgataccatc gggcaggact gtgtggccat gtgtgtcaac gacatcattg
    11161 ctgcaggtgc ggaacccctc tattttctcg actacgtagc gacagggaag aatgaaccag
    11221 ctaagctaga acaagtggtt gctggtgtgg cagaaggttg tgtgcaggct ggtgctgccc
    11281 tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg cgaagacgac tatgacttgg
    11341 ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat tgacggttca aaggtggtag
    11401 agggagatgt tcttctcgga cttgtttcaa gtgggattca ctcaaatggt tactctttgg
    11461 ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct accagaattg gaaggcaaga
    11521 aacttaagga agttctactt gagccgactc gtatctatgt caaggctgtc ttgccgctca
    11581 tcaaagaaga gttggtcaac ggcattgccc acatcacagg tggtggcttt atcgaaaatg
    11641 tccctcgtat gtttgcagat gacctagctg ctgaaattga tgaaagcaaa gttccagtgc
    11701 ttccaatttt caaagccctt gaaaaatacg gtcagattaa acacgaagaa atgtttgaaa
    11761 tcttcaatat gggtgtggga ctcatgttgg cggtcagccc tgaaaatgta gagcgtgtaa
    11821 aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat cgtcaagaaa gaaaacgaaa
    11881 gtgtcattat caaatgaaaa aaatagcggt ttttgcctct ggtaatggct caaattttca
    11941 ggtgattgcc gaagaatttc cagtggagtt tgtcttttca gaccatcgtg atgcctatgt
    12001 gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct tttgaactca aggagtttga
    12061 gagcaaggca gactacgaag cagcccttgt cgaactcttg gaagaacacc agattgactt
    12121 ggtttgccta gcaggctaca tgaaaatagt tggaccaacc ttattgtcgg cttatgaagg
    12181 tcggattgtc aacattcatc cagcctactt gccagaattt ccaggagctc atgggattga
    12241 ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc attcactggg tggattcggg
    12301 tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca cgactagctg atgataccat
    12361 tgacagattt gaagctcgca tccatgaagc agagtacagg ttgtatccgg aagtagtgaa
    12421 ggctctattt acagattgac tttttgatga ttcatatgat atctttgatt ttaaattgga
    12481 gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg taatgttaga atctaaaaaa
    12541 acaactcgat atgtatttta tgtctatctg atgttattaa cttggggaat cttatttaag
    12601 tttgaaacaa atcctgaatt tatagcattt ttcttagctc caaggtatat caattggatt
    12661 ccattttcag aaccactaat agtcgatgga aaaattgttt ttgctgaaat gttatttaat
    12721 ctgatttcct ttattccatt aggtgtttgt ttccctttga taaaaactaa tttatctagt
    12781 ttaagaatag tcgggacagg tttcttgatt agtttattgt ttgagtgctt acagtatatt
    12841 ttagcaatag gtataacaga tataacggat ttgactttaa atacgctagg tgtctgtgta
    12901 ggcttactga tttatcaaat ttttataaga gtgttcaaat cacagactag aaaatggatc
    12961 aatatcttag gtatgcttag ccttggtttt gcttatcttg ttttactgtt actgcattta
    13021 attggtgttt aactaatgat taaaaaggag aatataatga ctaaacgcgt cttaatcagc
    13081 gtctcagaca aagcgggcat tgttgaattt gcccaagaac tcaaaaaact tggttgggag
    13141 attatctcaa caggtggaac taaggttgcc cttgataatg ctggggtgga taccattgct
    13201 atcgatgata tgactggttt cccagaaatg atggacggtc gtgtgaagac actccaccca
    13261 aatatccacg gagggcttct cgctcgtcgt gacttggata gccacttgga agcggctaag
    13321 gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc tttacccatt taaggaaact
    13381 atccttaaac cagatgtgac ttatgctgat gcagttgaaa atatcgatat tggtgggcca
    13441 tctatgcttc gttcagcagc gaaaaatcat gccagtgtta cagttgtggt agatcctgct
    13501 gactacgctg tggttttgga cgagttgtca gccaatggtg aaacgactta tgaaactcgc
    13561 caacgtttag cagccaaagt atttcgtcac acagcggctt atgacgcctt gattgcagaa
    13621 tacttcacag ctcaagtggg tgaaagcaag cctgaaaagt tgaccttgac ttatgacctc
    13681 aagcaagcca tgcgttacgg tgagaaccct caacaagacg cggatttcta ccaaaaagcc
    13741 ttgccaacag actactccat tgcttcagcc aaacagctca atggtaaaga attgtccttc
    13801 aacaatatcc gtgatgcgga tgctgccatt cgtattattc gtgatttcaa agaccgtcca
    13861 actgttgtgg ctctcaaaca catgaaccca tgtggaatcg gtcaggctga taacattgag
    13921 actgcttggg actacgctta tgagtctgac ccagtgtcta tctttggtgg gattgtcgtc
    13981 ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc acggcgtttt cctcgaaatc
    14041 atcattgcac caagctatac ggatgaagcg ctagctattt tgatcaataa aaagaaaaac
    14101 ttgcgtatcc ttgccttgcc atttaatgct caagaggcta gcgaagtgga agcagaatac
    14161 acaggtgtag tcggtggact tctcgtgcaa aatcaagacg tggtcaagga aagcccagct
    14221 gactggcaag tggtgaccaa acgtcagcca actgagacag aagcgactgc tcttgagttc
    14281 gcttggaagg ctatcaagta cgtcaaatca aatggtatta tcgtgaccaa cgaccacatg
    14341 acacttggtg ttggtccagg tcaaaccaac cgtgtggctt ctgttcgcct tgccattgac
    14401 caagccaaag atcgtctgaa cggggcggtc cttgcttcag atgccttctt cccatttgcg
    14461 gataacgtgg aagaaatcgc caaagcagga attaaggcca tcatccagcc cggtggctct
    14521 gtccgtgacc aagaatccat cgaagcagcg gataaatacg gcttgactat ggtctttaca
    14581 ggtgtgagac attttagaca ttaagaagat aaaagggaag aaaacagttt ctttcctttt
    14641 ttggcttaaa atgctaactg aaacaagatt aaaacgaact tttttgatat aatattggta
    14701 aataattcgc aaaagaggtt gaggaatgaa actgcttgtt gtcggttcgg gtggtcgtga
    14761 gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtt gaaaaagtct ttgtagctcc
    14821 tgggaatgat gggatgactc tggatggttt ggaattggta aatatctcta tttccgaaca
    14881 ttctaaattg attgacttcg caaagaccaa tgatgttgct tggaccttta tcggtccaga
    14941 tgatgccctt gctgctggta tcgtggatga ttttaaccaa gctgggctta aggcctttgg
    15001 tccgactagg gctgcagcgg agctggagtg gtccaaggat tttgccaagg aaatcatggt
    15061 caaatatggt gtttcgacag cagcctatgg cacattttca gatttcgagg aagcaaaggc
    15121 ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg gatggcttgg cgcttgggaa
    15181 gggtgtcgtc gtttctgaga cggttgagca agcggtcgaa gccgctcatg agatgctttt
    15241 ggacaataaa tttggtgact caggtgcgcg cgtggttatt gaggaattcc ttgaaggaga
    15301 ggaattttca ctctttgcct ttgttaatgg tgataagttc tacatcatgc caacggctca
    15361 ggaccacaaa cgtgcctacg atggcgacaa agggcctaac acgggtggta tgggtgccta
    15421 tgcgccagtt ccacacttac cacagagtgt agttgataca gcggttgaca ccattgtcaa
    15481 gccagttcta gaagggatga ttaaagaagg tcgcccttat ctgggagttc tttacgcagg
    15541 gcttatcctg acagctgatg gaccgaaagt cattgagttc aacgctcggt tcggagatcc
    15601 agaaactcag attatcttgc ctcgcttgac ctctgacttt gctcaaaata tcacagatat
    15661 cctggatagc aaggagccaa atatcatgtg gacggacaag ggtgtgactc tgggtgtggt
    15721 tgtcgcatcc aagggctacc cgctagacta tgaaaggggc gttgagttgc cagccaagac
    15781 agaaggcgat gtcatcacct actatgcagg ggctaagttt gcggaaaata gcagagcact
    15841 gctctcaaac ggcggacgag tttatatgct cgttaccaca gcagataccg tcaaagaagc
    15901 ccaagccagc atctaccaag aactatacca acaaaaaata gaaggactct tctaccgaac
    15961 agatatcgga agcaaggcaa ttaagtaaag atataagaat aacgcgccgt agtcgccaaa
    16021 cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga atgttctggt cagggggaaa
    16081 cttggagacc gtaggctcaa agtttaggaa tgaaaccgaa ggtttgcttc cgcctccatc
    16141 acctaagacc attatcaaaa agaaaaataa aaattcacaa aatacgttaa tgatcgtatg
    16201 gtttgcgagc gttagcgagc taatatagaa caatcaccgc cgttgtgaaa gaacgattgg
    16261 atgataatcc aatcgttcag ggaaattgga agaccttggg tttccaattt aggcatgaga
    16321 cacctttggt ggctgctgcc gtccctcaca agctaaggtg attgttgaaa aagaggaaaa
    16381 aggagaagaa atgaaaccag taatttccat catcatgggc tcaaaatccg actgggcaac
    16441 catgcaaaaa acagcagaag tcctagaccg cttcggtgta gcctacgaaa agaaagttgt
    16501 ttccgcacac cgtacaccag acctcatgtt caaacatgca gaagaagccc gtagtcgtgg
    16561 catcaagatc atcatcgcag gtgctggtgg cgcagcgcat ttgccaggca tggtagctgc
    16621 caaaacaacc cttccagtca ttggtgtgcc agtcaagtct cgtgctctta gtggagtgga
    16681 ttcactctat tctatcgttc agatgccggg tggggtgcct gttgcgacca tggctatcgg
    16741 tgaagctgga gcgactaacg cagctctctt tgccctccgt ctcctctctg tagaagataa
    16801 gtccattgcg gatgcacttg ccaactttgc tgaagaacaa ggaaaaatcg cagaggagtc
    16861 gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg cggtcaactg ggtcagatga
    16921 tggccatttc tgctatctac atgggccaca aggttatcgc gctggatcct gcggcggatt
    16981 gcccggcctc tcgcgtggcg gaaatcattg tggcacctta taacgatgtg gacgccctcc
    17041 gtcagttggc agaccgttgc gatgtcctca cttatgagtt tgaaaatgtc gacgctgacg
    17101 gtttggatgc cgttatcaag gatggacaac tccctcaagg aacagatctg ctccgcattt
    17161 cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa ggctcaagtc actgtggcac
    17221 cctacaaggt cgtgacttct agcctagact tggcagatat cgacttgtcg aaaaactatg
    17281 tcctcaagac tgcgactggt ggctacgatg gtcatggaca aaaggttatt cgttcagaag
    17341 cagacttgga agcagcctat gcgctagcag actcagcaga ctgcgtcttg gaagaatttg
    17401 tcaactttga ccttgagatt tctgtcatcg tgtcaggaaa tggcaaggag gtgacgtttt
    17461 tcccagttca ggaaaatatc caccgcaaca atatcctgtc taagaccatc gtaccagccc
    17521 gcatttctga aagtctagta gacaaggcta aagctatggc agtgcgaatc gcagaacaac
    17581 tcaacttgtc tggaactctc tgtgtggaaa tgtttgcgac tgatgatgac gttattgtca
    17641 atgaaatcgc cccacgacca cataactctg ggcactattc tattgaagcc tgtgatttct
    17701 ctcagtttga cacccatatt ctcggtgttc tcggagcacc attaccagtc atcaaactcc
    17761 atgcgccagc cgttatgctt aatgtcctcg gtcagcatgt cgaggctgct gagcaatatg
    17821 tgacagaaaa ttcaagcgcc cacctccaca tgtatggtaa aatagaagcg aagcacaacc
    17881 gcaagatggg acatgtgacc ttgtttagtg atgtaccgga tagtgtggat gagcttgggg
    17941 aagggattga tttttaggac aagtctatga tacaaattat cgttaataca tttattgaaa
    18001 aggataagac tggagcagtt gttgaagtgt tgtatgccag tgctgaccaa gataaggtaa
    18061 aagctaaata tgaagaacta gctgcacaat accccgaaaa ttatttagct atctatgatg
    18121 taccgctgga tacggatttg aatacactag atcattaccc gtctgtgttt attgaaaaag
    18181 aggagtttga gtagaaatct tggtttacct agatagctta ttcccaacag cttaagaaga
    18241 aaggaaaaat taacacatga tcaaccgtta ctctcgccct gagatggcga atatttggag
    18301 tgaagaaaat aaataccgtg cttggcttga ggtggaaatc ctctctgacg aggcatgggc
    18361 tgagttgggg gaaatcccta aggaagatgt ggctttgatt cgcaagaagg cggactttga
    18421 catcgaccgt attttggaaa ttgagcagga gacgcgccac gatgtggtgg ctttcacgcg
    18481 tgcggtttct gagactcttg gtgaagagcg caagtgggtt cactatgggt taacttctac
    18541 cgacgtggtg gatactgctt atggttacct ctacaagcag gccaacgaca tcatccgtcg
    18601 tgaccttgaa aacttcacta atatcatcgc tgacaaggcc aaggagcaca agttcaccat
    18661 catgatgggg cgtactcatg gtgtgcacgc tgagccgaca acctttggtc ttaaattggc
    18721 aacttggtac agcgaaatga aacgcaatat cgagcgtttc gagcatgcag ctgctggtgt
    18781 agaagctggt aagatttctg gtgcggttgg gaactttgcc aatatcccac catttgtaga
    18841 ggagtatgtc tgcgataaac ttggcatccg tgcccaagaa atctctacac aagtccttcc
    18901 tcgtgacctt cacgctgagt actttgcggt tcttgccagc attgcgactt caatcgaacg
    18961 tatggcgact gagattcgtg gtctacaaaa atctgagcaa cgcgaagtag aagagttctt
    19021 tgctaaaggg caaaaagggt cttcagcaat gcctcacaaa cgcaacccaa tcggttctga
    19081 aaatatgact ggtctggcgc gtgtcattcg tggtcacatg attacggctt atgaaaacgt
    19141 cgctctctgg cacgaacgcg atatttctca ctcatcagct gagcgtatca tcacaccaga
    19201 tacgaccatt ttgattgact acatgctcaa ccgttttgga aatatcgtca agaacttgac
    19261 agtcttccca gaaaatatga tccgaaacat gaactcgact tttggtctta tctttagcca
    19321 acgggctatg ttgacattga ttgaaaaagg catgacccgt gagcaagcct atgacttggt
    19381 gcaaccaaaa acagcctact cttgggacaa ccaagtagac tttaaaccac ttcttgaggc
    19441 agattcagaa gtaacatcac gtctcactca agaagaaatc gatgaaatct tcaacccagt
    19501 ttattacacc aaacgagtgg atgatatctt tgaacgtctt ggactaggtg attaattaaa
    19561 aaataaacag cgagcttcaa tctcgctgtt tattttttat cgaaaagact tagtcttctt
    19621 ttcttttagt gagtccatag gctgctagtg tggacatgag tcctgcgact actagtcctg
    19681 cagaatcgtg agttcctgtt tcaggaagtt ttttctctgt taccacagga gctggatctt
    19741 gaggaagagc tttgctttcc tcagcgggag cagttgatgg agctggttgg cttgggattt
    19801 ctagttttgg tttttcttca gcaatagcgg cttgtccgtt ttcatcgcct acatgtgtta
    19861 ccatagttcc gacttcgact atttgagtaa cggcttcctg tgctacgaca ctatttacaa
    19921 gtgttttcac ttccttacca tcggcagaag tgctcacaga gtagaagttg ctacgatgtc
    19981 cattgacgcc cttagtaatg acttgtgttt ttcctttgag taagagtgga ttttcacgag
    20041 tcactgtggt aaatggaatt tcttcttttt ggatatccag tctaggtttt acctcagtag
    20101 ttggtgcaag accactttca tcacccttgt gagttacagg agcgccaact tcaaccactt
    20161 ggtttataac ttctttggtt acctggctat caaggactgt ttctgttgtt tttccatttt
    20221 cagtgagtac agagatgtaa tgagttcgtt cacctttgac tcctgctgtg ataatatttt
    20281 cctgaccagc tgggaggtta ggattttctt tcttgataac ttcaaatgga atttcttcag
    20341 ttcttgtgat gagttctggt ctggtttcaa cattggcagc cacttcattt tcatccaggc
    20401 ttcctgaatg agttgcagct ggtttgaggc cttgaagagc ggcttttagg ttggctacaa
    20461 gtgtgtcaag ctcagcttgt ttattacggt tgaggttgta atttagagct gttttagctg
    20521 cgtcaagggc ctcaagactt tctttactat atccttctaa gtttgtagga attttagcta
    20581 attcttcgcg gagagcatta taattagcac ggaagtagtc tttgttgtgg tctgcaaagg
    20641 cagtcatgag ttcaaagatt tcctcttcct tgtactcagc gcttggtcta tctgcccaga
    20701 ttgaaagcat acttccgact gttggaagat ctacttcagg atatttggta gaagctagtt
    20761 gattgaatgg tgtttttcca gtattctcaa tagctttctt gaggaaacca ccaccatctt
    20821 ctggtttttg accaagaatg tagtaccagt caccgttggt attcaagaat ttatagcctt
    20881 tgcttgctag gtattgaggt gatgcgaggt tatatcccca ccagccttta gaccagtaag
    20941 aaatcaagac atctttgtca aactgaacat cgtccttgtc ttcatagtag aagccatcgt
    21001 tgaaggccat tggttgaagc cctctttctt tggccatagc tgcgagggtg ttggcatatt
    21061 cggcaaattt gccatagagt tgataccact tgaggtagta ccagccttgg gcactagtcg
    21121 catcgttggc gtattcgtca gtaccaaagt tgaaaatctt tgttttacct gcaaagaagt
    21181 ccatgtattt accgatgagg gcttttacaa agttcatcgc ttcttcgttt ttcaagtcca
    21241 tagttgtttt tgaaacttta tcaaagtggg cttgaggatt tttaatacct aatttttcca
    21301 tggcaaccag catagcatcc atgtgacctg gactgttaat agctgggatg agaccgatgt
    21361 ccttagattt agcgtattca attagctctg ttacttctgc ctgtgttagt gcagtaccgt
    21421 ttggatcgtc gtagtaagct ttagttcctt cgataatagc ttttttaacg tcatcactag
    21481 cataggtttt tccgttggca gtaatggtca tatcatcgag tagaaagcga agtccgtcat
    21541 ttcctagaag gagatggaca tcagaatatc cgagctcact tgccttgtct acgatgcgtt
    21601 tgagctggtt cagagtaaag tatttgcgtc cagcatcgat tgagattacc ttgtttttgg
    21661 caagtttttc aacctcacgt ttagcttctt cttcttttag agcttcaggc gtgagggtca
    21721 agttgttgac agtttcttga agtttagcaa tggcttgatc aatcgtatct tgttgggcac
    21781 ggctaaggtt gctatcgaga gagcgaatag ctttttcagc ttcttttacg gccgtgacgc
    21841 tttctgcagt ataacggttc aggtcttttg gtacctcgtt aagtgcttgc tctgcagatt
    21901 cataatcagc tgcgaagtat tcagcgttgg catttgcaaa atgacgcatg agtttgaaga
    21961 ggcgtgatgg tgaataacgt gcagatggag tgtcagccca agcagctacc ataccaccga
    22021 tgattgggat atcagctcct tctgtttttg gtacagaagt gattggtgtg tttttaatac
    22081 cattgagccc ctgatcgaga ttgtaccagc cttggccatc agcgtttcgt ccaagaacgt
    22141 agtaccaagc atcattggta ttaaggattt ggtgaccttt ttcagctagt agtttagaag
    22201 aagcgacatc gtagcctccc caaccaccag tccacataga aacgatgatg tctttgtcaa
    22261 aactaccaaa gcttgtgtcg ctattgtagt agataccgtc gttaaaagcc attggtttga
    22321 gaccgtgcga ttttacaata cgagcgaggt cattggcgta ggcaataaat ttttcatagc
    22381 cttttacagg gtagccttcg tttggatagt atttatcagc ttgaagcaca ctccaacctt
    22441 tagcatctgt cgcatcattg gcatattcat caagtccgat gttgaagatt tcagtctttt
    22501 tcgcgaaata agcagcatac ttgtcgataa gggcttttgt aaaagcgaca gcttgttcgt
    22561 tgtcaagatc gacagtacgg gctgatttct tcccaaaata gctaaagtta gggttttgga
    22621 ttcccaattc tttcatggca ttgagaatcg catccatgtg tccaggacta tttactgtcg
    22681 gaatgagacc gataccttta tctttggcat agttaatcag atctgtcatt tgactttctg
    22741 ttaagtgatt gccgtttgga tcgttgtaat aatcatttgt acctttttca atggcgcgtt
    22801 tgacatcgtc actggcatag gtcttgccgt tagctgtgat gctcatatcg tccaacatga
    22861 aacggagtcc atcatttccg actaataggt gtaaatcagt gtagccataa tgtttcgctt
    22921 tatcgatgat ttccttgagt tgttctggtg agaaatattt acgtccagca tcaatagaaa
    22981 caattttctt tttcgctagt ttttcattta cagttgcagc acgttccttt cctgcctctg
    23041 tttccggttt gtcagcctct gctttcgctt catctttttt agctggttta tccttgtcag
    23101 tcttgtctgt atttgactct ttagaatcaa cctctttcgc ttcttccttt ttagggctag
    23161 cttcttctgc ctttttatta gcagtttctt tttcagcaga agttggagtt accacttctg
    23221 ctttatcact aggagttgaa ctaacttcct cttgtggttt ttcttctgtt tttggaagac
    23281 tagctacctt atcagtagct ggagtttctg tttctacagt ttttggagct tctggttgaa
    23341 gcactgcttt aggtgtttcc tcagtccgat tttcggatga ttgaggggaa tcagaaaccg
    23401 tatggatggt cggttggttt tctgtagtag taggagtaac tccatcggct gcaacagtct
    23461 gtgcttggaa ggcaaatcca attagaacag aagctgctcc tacagcgtat ttacgaatag
    23521 aaaaacgctg ttgtttttca tgtttcattg caaaacctcc tgattgcatt gttatattga
    23581 tagcgattat ataaatcaac gcctttattt tatttcttat attaacgaga gtcaagagga
    23641 gatgacaaaa aactataata agtataaaaa aatataaaat ttaaacttaa gatttcagat
    23701 tggtcggaaa aaatacgtat atatatctag tataattttt ggttctattt ctataaaata
    23761 ttccacaaat tatagaattt tccaaaaata ggtaagcgct acctttttgg tgtggtataa
    23821 taagcataga aaaagcccaa gcgattagct caggctttct tcttagtgat cacggtcaca
    23881 tgagataaat ttaatcttgt agtaatcaga tcgtttgtaa gtttcactgt attctaaaac
    23941 ttggccagtt gattcgagtt tggtgatttt agtttgtagg acagtaggga attgttcatc
    24001 gactccgagg actgaagccg catgttctgg agttggaaag actatttcgt tgatttcttc
    24061 aaagtgttca tcattcatgt gaatgtggta gtctaacttg aaacgattat agatagaact
    24121 atagtattca aggtttggat aatttgcgtt gatatattgt tctgggatgt aggatgtatg
    24181 gtagatataa acgacaccgt ttgattcgcg gatacgttca atcttgtagt agaattgatc
    24241 gccacgtaga cccaattttt ccaagtaaac aagcttgttt ccgcgttcaa ttgaaagaac
    24301 agttacctta tcatctttag cattgaagag ttcaatatct gaaaactcta caagcttgtg
    24361 tttgcgtgca cgtgaaacga aggttccttt tccttgttgg cggacaatat agccatcttt
    24421 ggcaaggtcg tttaaggcgc gaacaactgt gatagagctg acatcgtaca ttgaaatgag
    24481 ttctgcttca gtgtaaaatt tatctccact gctaaactgc ccagagatga ttttattttt
    24541 taattcgtct tttatgtatt gatatttggg aattgccata tttttacctc tattttcctt
    24601 ctccatagaa aattttacca taaaagcgaa aaaaatagta gtcttttgaa taaaaaatta
    24661 gaataatagt ctgaaaaatt aagcgatata gggattgctc atattttatc aatgtattct
    24721 atacaaaatt attttaggtc ctatattccg aatttaaaga gcgtttgaaa tgggtctaaa
    24781 aatgtttgaa actaattgaa tgtgtgtata atagtaaaaa tgcagtaaat atcccgacaa
    24841 tttctattga caattcaaac agattggttt ataattaata taacaacaaa tgaaagcgca
    24901 aactttcgcg gtcggaaggt agttttatga cacgatttga gatacgagat gatttctatc
    24961 tcgatggaaa atcatttaag attttatctg gtgccattca ttattttagg gttcctccag
    25021 aggattggta tcattcgctc tataacttga aggctcttgg ttttaatacg gtagagactt
    25081 atgttgcttg gaatttacac gagcctcgtg aaggtgagtt tcattttgaa ggtgatctgg
    25141 atttagagaa atttctccaa atagcgcagg atttgggtct ctacgcaatt gtgcgtccgt
    25201 ctccatttat ctgtgcggaa tgggaattcg gtggcttacc agcttggctc ttgaccaaga
    25261 acatgcgaat tcgctcatcc gacccagcat atatcgaggc agttggtcgc tactatgatc
    25321 agttattgcc aagactggtg cctcgtttgt tggacaatgg tggcaatatt ctcatgatgc
    25381 aggttgaaaa tgagtatggt tcttacggag aagataaggc ttacctgaga gcgattcgac
    25441 agctaatgga agagtgtggc gtaacctgtc ccctctttac atcagatggt ccatggcgag
    25501 ctactctgaa agctggaacc ttaattgaag aggacctctt tgtaacagga aactttggtt
    25561 ctaaggcacc ttacaacttt tcgcagatgc aggaattctt tgatgaacat ggtaagaaat
    25621 ggccactcat gtgtatggag ttctgggatg gttggttcaa tcgctggaaa gaaccgatta
    25681 tcacacggga tcctaaggaa ttggcagatg cagttcgaga ggttttggaa caaggctcta
    25741 tcaatcttta catgttccac ggtggtacaa actttggttt catgaatggt tgctcagctc
    25801 gaggaacttt ggacctgcca caagttacgt cttatgatta cgatgccctt ctggatgaag
    25861 aaggaaatcc aactgctaaa tatcttgcag tcaagaagat gatggcaaca catttttcag
    25921 agtatccgca gttggaacca ctctacaaag agagtatgga gttggatgct attccactag
    25981 ttgaaaaagt ttctttgttt gaaaccttag atagcttgtc aagtcctgta gaaagtctct
    26041 atcctcaaaa gatggaggag ctgggacaaa gttatggcta cctactttat cgaacagaaa
    26101 caaactggga tgcagaagaa gaaagacttc gtatcattga tggtcgagat agggcccagc
    26161 tgtatgtcga tggtcagtgg gttaaaactc aatatcagac agagattggg gaagatattt
    26221 tttatcaagg taaaaagaaa gggctatcta ggttagatat cttgatagaa aatatggggc
    26281 gtgtcaacta tgggcataag ttcttagcgg atacgcaacg taagggaatt cggacagggg
    26341 tctgtaagga tctgcatttc ttactaaact ggaaacacta tccactccca ctagacaatc
    26401 ctgagaaaat tgatttttca aaaggatgga ctcaaggaca accagccttt tacgcttatg
    26461 actttacagt cgaagagcca aaagatactt acctagactt gtctgagttt ggtaaggggg
    26521 ttgcctttgt caatgggcag aatctaggac gtttttggaa cgttggccca actctctcac
    26581 tttatatccc tcatagctat ctcaaggaag gtgccaaccg catcattatc tttgaaacag
    26641 aaggtcaata taaagaagag attcatttaa ctcgtaaacc tacactaaaa catataaagg
    26701 gggaaaactt atgacaattg taggatgccg tattgatgga cgtttgatcc acggacaagt
    26761 agccaatctt tgggctggaa aactaaatgt ttcacgcatt atggttgtag acgacgaagt
    26821 tgtcaacaac gatattgaaa agagtggttt gaaacttgcg acaccaccag gtgtgaaatt
    26881 gagtattttg ccagttgaga aagctgcagc caatattctt gctggcaaat acgatagcca
    26941 acgtctcttt atcgtggctc gtaaaccaga ccgcttcctt ggtttggtag aagcaggtgt
    27001 accacttgaa acccttaatg ttgggaatat gtctcaaaca ccagaaactc gttctattac
    27061 acgttctatc aacgtagtag acaaggatgt ggaagacttc cacaaactgg cagaaaaagg
    27121 tgttaaactt actgctcaga tggttccaaa tgatccaatt tcagactttt tgagcttatt
    27181 aaaataggaa aaaaattttt aggaggtcat tgttatgata caatggtggc aaattttact
    27241 tctcactttg tactcagctt atcaaatctg tgatgagttg acgatcgttt catctgcagg
    27301 ttcccctgta tttgctggtt tcattactgg tttaatcatg ggagatgtga ctactggttt
    27361 acttatcggt ggtaacttgc aactgttcgt tcttggggtt ggtaccttcg gtggtgcttc
    27421 tcgtatcgac gcaacttctg gtgcggttct tgcgacagcc ttctctgttt cacaaggaat
    27481 tgatgcaccg cttgccatta ctacaatcgc tgtaccagta gcagctctct tgacttactt
    27541 cgacgttctt ggtcgtatga ctactacctt cttcgctcac cgtgtggatg ctgcaatcga
    27601 acgctttgac tataaaggta ttgaacgcaa ctacttgctt ggtgcgattc cgtgggctct
    27661 atctcgtgcc cttccagtct tctttgccct tgcttttggt ggtgcctttg tacaatcagt
    27721 agtagacttc gttgaagcct acaaatgggt tgcagatggc ttgacacttg caggacgtat
    27781 gcttccaggt cttggatttg caatcttgct tcgttacctt ccagttaaac gtaaccttca
    27841 ctaccttgct atgggatttg gtttgacagc tatgttgact gttctttact catatgtaac
    27901 aggtcttggt ggcgctgttg ctggtatcgt aggtactctt cctgctgaag ttgctgaaaa
    27961 aattggtttc gtgaacaact tcaaaggttt gtctatgatt ggtatttcta tcgtaggtat
    28021 tttccttgca gtgcttcact tcaaaaatag ccaaaaagta gctgtagcag caccttctac
    28081 accatcagaa agtggggaaa tcgaagatga cgaattctaa ttacaaactt acaaaagaag
    28141 attttaatca aatcaacaaa cgtagcttgt ttactttcca attaggttgg aactacgaac
    28201 gtatgcaagc ttctggttac ctttacatga tcttgcctca gttgcgtaaa atgtatggtg
    28261 atggaactcc tgaattgaaa gaaatgatga aagttcatac tcaattcttc aatacttcac
    28321 cattcttcca taccattatc gctggttttg accttgccat ggaagaaaaa gatggtgtag
    28381 gttcaaaaga cgccgttaac ggtatcaaga caggtttgat gggaccattc gctcctcttg
    28441 gggatacaat ctttggttca cttgtacctg ctatcatggg gtcagtcgca gcaactatgg
    28501 ctatcgctgg ccaaccttgg gggatcttcc tttggattgc agttgcagta gcgtatgaca
    28561 tcttccgttg gaaacagttg gaatttgctt acaaagaagg ggttaacctt atcaacaaca
    28621 tgcaaagtac cttgacagct ttgattgacg ctgcatctgt acttggtgtc ttcatgatgg
    28681 gtgctcttgt agcaacagtg attaactttg aaatttctta caagttgcca atcggtgaaa
    28741 agatgattga tttccaagac atcttgaacc aaatcttccc acgtttgctt ccagcaatct
    28801 ttactgcctt tatcttctgg ttgcttggta agaaaggtat gaactctact aaagctatcg
    28861 gtattattat cgtacttgct ttggctcttt ctgcccttgg tcactttgca cttggaatgt
    28921 aattccttat gactaaatca ttaattttgg tgagccatgg tcgcttctgt gaggagctta
    28981 gaggtagcac agaaatgatt atgggcccac aagacaacat ttacacagta gctcttcttc
    29041 cagaagatgg cccagaagaa tttactgcta aatttgaagc tgttattgaa ggattggatg
    29101 atttcctagt ctttgcggat cttctcggtg ggacaccttg taatgtggtg agtcgcttga
    29161 tcatggaagg tcgtgatatt gacctttacg cagggatgaa tcttccaatg gtgattgaat
    29221 ttatcaatgc gagccttaca ggcgcagatg cggactacaa gagccgtgct gcagaaagca
    29281 ttgtgaaagt taatgacctg ttagcgggct tcgatgatga cgaagatgaa taatactctt
    29341 cgaaaatctc ttcaaactac gtcaacgtc
//
LOCUS       DBEJZJ010000024        29153 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000024 DBEJZJ010000000
VERSION     DBEJZJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.24"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..280)
                     /gene="tnpB"
                     /locus_tag="ACL3R8_001352"
     CDS             complement(<1..280)
                     /gene="tnpB"
                     /locus_tag="ACL3R8_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1314222.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWLSTEKDVKALAPEQ"
     gene            complement(261..446)
                     /locus_tag="ACL3R8_001353"
     CDS             complement(261..446)
                     /locus_tag="ACL3R8_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314223.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(750..2312)
                     /gene="guaA"
                     /locus_tag="ACL3R8_001354"
     CDS             complement(750..2312)
                     /gene="guaA"
                     /locus_tag="ACL3R8_001354"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR1314224.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2454..3152
                     /locus_tag="ACL3R8_001355"
     CDS             2454..3152
                     /locus_tag="ACL3R8_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1314225.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3195..4091)
                     /locus_tag="ACL3R8_001356"
     CDS             complement(3195..4091)
                     /locus_tag="ACL3R8_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR1314226.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4100..5035)
                     /locus_tag="ACL3R8_001357"
     CDS             complement(4100..5035)
                     /locus_tag="ACL3R8_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR1314227.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTASELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5032..5757)
                     /locus_tag="ACL3R8_001358"
     CDS             complement(5032..5757)
                     /locus_tag="ACL3R8_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR1314228.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     SYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5841..6476)
                     /locus_tag="ACL3R8_001359"
     CDS             complement(5841..6476)
                     /locus_tag="ACL3R8_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR1314229.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6478..7305)
                     /locus_tag="ACL3R8_001360"
     CDS             complement(6478..7305)
                     /locus_tag="ACL3R8_001360"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1314230.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7327..7663)
                     /locus_tag="ACL3R8_001361"
                     /pseudo
     CDS             complement(7327..7663)
                     /locus_tag="ACL3R8_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(7664..8380)
                     /locus_tag="ACL3R8_001362"
     CDS             complement(7664..8380)
                     /locus_tag="ACL3R8_001362"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR1314231.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSEMVEKDGDKKLIIY"
     gene            8893..9504
                     /gene="def"
                     /locus_tag="ACL3R8_001363"
     CDS             8893..9504
                     /gene="def"
                     /locus_tag="ACL3R8_001363"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR1314232.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9549..10277
                     /gene="rlmB"
                     /locus_tag="ACL3R8_001364"
     CDS             9549..10277
                     /gene="rlmB"
                     /locus_tag="ACL3R8_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR1314233.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10316..11227)
                     /gene="trxB"
                     /locus_tag="ACL3R8_001365"
     CDS             complement(10316..11227)
                     /gene="trxB"
                     /locus_tag="ACL3R8_001365"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR1314234.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11293..11517)
                     /locus_tag="ACL3R8_001366"
     CDS             complement(11293..11517)
                     /locus_tag="ACL3R8_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR1314235.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11595..12338)
                     /locus_tag="ACL3R8_001367"
     CDS             complement(11595..12338)
                     /locus_tag="ACL3R8_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1314236.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12338..13138)
                     /locus_tag="ACL3R8_001368"
     CDS             complement(12338..13138)
                     /locus_tag="ACL3R8_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1314237.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13296..13652)
                     /locus_tag="ACL3R8_001369"
     CDS             complement(13296..13652)
                     /locus_tag="ACL3R8_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR1314238.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13665..14177)
                     /locus_tag="ACL3R8_001370"
     CDS             complement(13665..14177)
                     /locus_tag="ACL3R8_001370"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR1314239.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNK"
     gene            complement(14177..14671)
                     /locus_tag="ACL3R8_001371"
     CDS             complement(14177..14671)
                     /locus_tag="ACL3R8_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR1314240.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14806..15252
                     /locus_tag="ACL3R8_001372"
     CDS             14806..15252
                     /locus_tag="ACL3R8_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR1314241.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15249..15896
                     /locus_tag="ACL3R8_001373"
     CDS             15249..15896
                     /locus_tag="ACL3R8_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR1314242.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15917..16498)
                     /gene="pdxT"
                     /locus_tag="ACL3R8_001374"
     CDS             complement(15917..16498)
                     /gene="pdxT"
                     /locus_tag="ACL3R8_001374"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR1314243.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16499..17374)
                     /gene="pdxS"
                     /locus_tag="ACL3R8_001375"
     CDS             complement(16499..17374)
                     /gene="pdxS"
                     /locus_tag="ACL3R8_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR1314244.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17526..18905)
                     /gene="nox"
                     /locus_tag="ACL3R8_001376"
     CDS             complement(17526..18905)
                     /gene="nox"
                     /locus_tag="ACL3R8_001376"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR1314245.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19199..20122
                     /locus_tag="ACL3R8_001377"
     CDS             19199..20122
                     /locus_tag="ACL3R8_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR1314246.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20182..20787
                     /locus_tag="ACL3R8_001378"
     CDS             20182..20787
                     /locus_tag="ACL3R8_001378"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR1314247.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20806..22050
                     /locus_tag="ACL3R8_001379"
     CDS             20806..22050
                     /locus_tag="ACL3R8_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR1314248.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22167..22424)
                     /locus_tag="ACL3R8_001380"
     CDS             complement(22167..22424)
                     /locus_tag="ACL3R8_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR1314249.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22466..24502)
                     /gene="glyS"
                     /locus_tag="ACL3R8_001381"
     CDS             complement(22466..24502)
                     /gene="glyS"
                     /locus_tag="ACL3R8_001381"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR1314250.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24714..25631)
                     /gene="glyQ"
                     /locus_tag="ACL3R8_001382"
     CDS             complement(24714..25631)
                     /gene="glyQ"
                     /locus_tag="ACL3R8_001382"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR1314251.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25826..26587)
                     /locus_tag="ACL3R8_001383"
     CDS             complement(25826..26587)
                     /locus_tag="ACL3R8_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR1314252.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26860..27702)
                     /locus_tag="ACL3R8_001384"
     CDS             complement(26860..27702)
                     /locus_tag="ACL3R8_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR1314253.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            complement(27816..>29153)
                     /gene="pgdA"
                     /locus_tag="ACL3R8_001385"
     CDS             complement(27816..>29153)
                     /gene="pgdA"
                     /locus_tag="ACL3R8_001385"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR1314254.1"
                     /translation="LALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLS
                     EGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEES
                     GLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQL
                     IKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIAL
                     PVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYD
                     IKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVL
                     TKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVAN
                     GSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE"
BASE COUNT         8614 a         6570 c         5233 g         8736 t
ORIGIN      
        1 cttgttcagg tgcgagagct ttgacatcct tttctgtact tagccaagtc agttttccgt
       61 tctcaaagcg tttatataat atccaaaatc cttgaccatc ccagtaaagg actttaaagc
      121 ggtctttacg tccaccacaa aagagaaaga cttgatcgga gaaaggatcc aattcaaagt
      181 gggttttaac cagataagcc agtgaatcga ttccttgtct catatccgtt ttcccacata
      241 cgagatagac ctgccctagg ctagatagat gaattgtcat agagcaacac cttatccaaa
      301 agctgttcta tcatttcgag attgagagat tgaaaaaaac ttacttcaag cttgccaata
      361 cgaattttaa gcagaatatc atttctcttt ttagaatcaa aaggacgaga ttgtggaatc
      421 tctacaggaa caataggttg tggcattaaa atatcctcca atagttttac tttactaata
      481 gtatacagga ggagctccat gaatgataga taccttgtta tgacgcgctt actatattag
      541 aaagttggct ctctaattaa attaattctc attatatata tcaaaagacc gcagtttgaa
      601 aactacggtc taattttttg tccaaatgta aaccacttgg aactattatt caatttattc
      661 tttttagcaa atgttcccgt tttaatccca gttacagttt ttaatcctct gtaaccgttg
      721 attttacaaa gcttttaatt tttttgcgat tattcccact caactgttgc aggtggttta
      781 cttgtaatat cgtagacgat acggttaaca tgatccactt catttacgat acgtactgag
      841 attttttgaa gtacttccca tggaattttg gcaaaatcag cagtcatacc atcgatagaa
      901 gtgatagcac ggattgcaat cgtgtagtca tacgtacgac cgtcacccat aacaccgact
      961 gaacgaacgc ctgtgttaac agtgaagtat tgccaaatat cgcggtcaag tccagcttta
     1021 gcgatttctt cacgaagaat agcgtctgat tcacgaacgg tttcaagttt ctcttcagtg
     1081 atttcaccca tgacacggat agcaagtcct ggtcctggga atggttggcg ccatacgata
     1141 tggtctggca taccaagctc tgtaccaaga gcacgaactt catccttgta aagagtattg
     1201 agtggttcaa tcaattcaaa ctgcatatct tctggaagac cacccacgtt gtggtgtgac
     1261 ttgatagttt gagctgtatc cgtaccagac tcgataacat ctgtatataa agtaccttga
     1321 gcaaggaatt tcacatcttt gagcttgctt gcttcgtcat cgaatacata gacaaactcg
     1381 ttaccgatga ttttacgttt ttgttcagga tcagaaacgc cagcaagttt gtcaaggaaa
     1441 cgtttagcag cgtctgcttt gacgatattc aaaccaaact taccaccgag catgtccata
     1501 acttgatcag cttcgccttt acgaagaaga ccgtggtcta cgaagataca gatcaattga
     1561 tcgccaatcg ctttttggag aagaacccca acgacagatg agtcaacacc acctgataga
     1621 ccaagaagga cacgtttatc accgacggtt tcacgaattt ttttgatctg catgtcaatg
     1681 aaattatcca ttgaccagtc acctttagcc ttacaaatgt taagggcaaa gttacgaagg
     1741 atatcatttc cgtatacaga atgacgaact tctgggtgga attggatacc gtaaatgtgt
     1801 ttatctgggt tttcgatggc tgcgtatggg cagtcagctg atgtacctgt acgaacaaag
     1861 tcagcaggaa tctcagtaac cgcatcacca tggctcatca aaacagtctg ttcatcaggt
     1921 gttgattcaa aaagcgctga tggtgtgtga gttagggttg attgaccgta ttcacgattt
     1981 ccagcatcac ctgcaggaac aacttttcct ccaagtttat gggtcaataa ctgcatacca
     2041 taacagattc ccaaaattgg aattccgagt tcgaagattt ctgggtcaat atcaaatgaa
     2101 ccatcttcat atacagaatt tggaccacct gatagaataa ttcctacagg attgacttca
     2161 cgaacttcag cagctgaaat tttatggctt tttagttctg aaaaaacacc aatctcacgg
     2221 atacggcgtg aaatcagctg gttgtactgg ctaccatagt ccaatacgat gattttttct
     2281 acatcttgca aatcagttga aatgttgctc atctttttcc tttctcaaaa gaaatatctt
     2341 ttcccaatat tctatcacaa ataagggcga attaccaact aaacaaggcg aagtttgact
     2401 ttttctagtt tattggggta caatagagaa aagatagaaa tgaagtgaaa aatatgctac
     2461 ctgcttatat gaaaatccat gatcagataa aaaaggatat tgacgagtac cgttgggcta
     2521 ttggtgagag gcttcccagt gaaagagatc tagctgagca gtttgcggtc agtcgcatga
     2581 ccctccgcca agccgtatct ctattagtcg aagaaggcgt cttagagcgc cgtgtaggaa
     2641 gcggcacctt tgtttccagt actcgagtac aagaaaagat gcgagggaca accagtttta
     2701 ctgaaattgt caaatcccaa ggtaaagttc cctctagcca gctcatttcc tacaaaaaaa
     2761 ccattcccaa tgagcaagaa gttgccaagc taggaatttt tccaacggac aatattatcc
     2821 gaatggagcg ggtccgctat gccgaccaag ttcccctagt ttatgaagtt gcttctattc
     2881 ctgaaaaatt cattaaggac tttaaaaaag aagaaatcac cagtcatttc ttccaaacct
     2941 tgcaaaaaca tggctatcgt atcggcaaat ctcaacagac catctatgct cgccttgcta
     3001 aagaaaagat tgcccactat ttggaagttg aaaaaggaca tgctattctt ggattgaccc
     3061 aggtttccta cctagaagat ggtactgctt ttgaatacgt aaaaagtcaa tatgtaggcg
     3121 aacgctttga attttatctt gaaaataatt agattaccac gcaaaaactc tctgtcacga
     3181 acaaagagtc ttttttattt ttctaagaat aaatctttca aagaaatcaa agttacagca
     3241 aacaatatca ttgccatacc aagaaaatca atgggataaa attgttcatt cattattaag
     3301 aaggcaaaga aaatcgccga tattggctca attgaagcca acaagcttga cttgaccggt
     3361 cctatcagac tggctccttt aaggaaagct gtataggcaa agacagtccc gataaggata
     3421 atgcctgcaa acgcaaggag aaaatcaaga ctagtcggga tatcggcctg tagaacccct
     3481 gtaaaaggaa gggcgaccaa acctgctatg accattccca caccaatgac caagctgctc
     3541 ccccactttt taatcaaggc tatgggtaaa atgatataca gagcataagt caaggcagaa
     3601 aagagacccc agaacagacc agcaggtgtc atggataact ggtccaactg cccatgtgtt
     3661 gcgatcagga aggttcctcc gatggcgaat atgatggaaa ctatctctcc cagtgtcggt
     3721 gccaccctat ccttgataca gctataaatt aaaattccga caggacaaac atactgaagc
     3781 accgtcgctg ttcccgcatt ggtctcctga atagcagaca gataggcgaa ttggttgaga
     3841 aaaagaccaa tcagagcaaa aataagaaga gacagcaaac tctttctatc ctttaaaaag
     3901 accagtattt tatcctttgc agtagcataa gccaagagca tgagaattcc accagcgatt
     3961 aaaagacgca agttagtcaa gaccagagcc gaaattccgt gtgccattag gtattggcca
     4021 ctcgttcctg acaaccccca agcaatacca gccacaactg ttagtaaagt cccttttaaa
     4081 ctatttgaca tgtctctcct tactcttctt tgcgaatcaa gttcatcact tgattgcggt
     4141 ctaatatcca ttgagctctc tcgtcctttt cataggtacg attcgatagg aaaatagtgg
     4201 cttcttgctt ctgacgattc cacatgataa aggtacctgt atagcccgta tggtctagcc
     4261 aatctccttc caaattccat gctaaagaac gttccttgtc atccaaagga gaaaaatttt
     4321 gatttaagtc tcttgcaaaa tcatctgcta aatagtgttc taaaaagatt tgtaaatcct
     4381 ttatagtcga aaataaacca gcactcccag catgtctacc caggagacga gccttgggat
     4441 catgcactat gcctgcctct acacctctaa ctgttggaac agcaagctca actggcccaa
     4501 acttggtttc cgtcattccc caaggtttcc agacttgatc ctttaaaatc acatccaaat
     4561 cttgattaaa aattctttcc aaaataaagc ccaacagcaa aaaatggaca tccgaataaa
     4621 gaaaggctgg ctgacttcgt ctgttgagat gaaacatcgc ttcctttaat tcagaggctg
     4681 ttaaaagatc acgattagga ataaaaggat caaggtctgt tgcatgagtc aagagctggc
     4741 gaatagtgat gtctggataa tcactctcag gtaaaaaatc tattaccagt ctatcaatat
     4801 ctaattgacc tatttcccac aagaaggtac aaactgtgcc aaccccaaca accttgctga
     4861 cactagctag gtcataaact agtcctgcct cagtctgcaa gccatgctct ggggcactct
     4921 ggcctaaata gaactctgtc cattgattgt ccttaaaata cgcaaaagag gctccgggat
     4981 aaattcctgc ctcgatttgt tcttctattt ttttaataat cttggtccac ttcatacttc
     5041 ttcaaaccac aattcaacat tatttctatc tttaccaagg aagaattttt cagacttagg
     5101 aataaaatat tcagtagact caaacttctg gcgaagactt gctatgtcta attcattgac
     5161 caagaacttg agcatagata agtcccaggt aaccgtattg tccacagtca aatcctgccc
     5221 ctgagctgga ataaaatcaa gggatgcccc aatttcagat gattccaaga aactttcgat
     5281 atcagttggg agatgtaatt ccatagaaat ctcaaattta cttaaagaaa ttgatgccaa
     5341 atctgtttga aattcaggct tttctcctac ttctactaga cttgctatgt catcttccgc
     5401 atgaatcaaa atcaaatcat cttctggtga gaaaatttca aaagcgtagc tattttgacc
     5461 tttatataat cgatgaatcg aatctgtttt agataagatt ccttcaattt ctaagggatt
     5521 ttccaccttg acaatcaatc tagctagttt ttttcttccc tctaccttac gagtacgcat
     5581 actgggagct tcttctaaaa ccagcttttc aagacccgtt tggtcaccta gtgacagaaa
     5641 ggccgattct tctaacaagg ccttcattcc aagggtttca atataaaatg tttcatttaa
     5701 ttttctatta ttagctttta aagtaggaat aatccgtaca atctgattta cattcataaa
     5761 ttcctccgtc actttttatt ttaaaggatt ttagaatttt ttacaagata ttatgctcaa
     5821 atttaacatt atttagctat ttagtaaaga tagtctttca aggcttttga caaagcctga
     5881 taaccagcaa tactgaggtg cagtccatca gttgtatatt cttttttgag ttggcctgct
     5941 tggtctgtca aacaatcaaa tactggcaca aattccacct gcatataggc agatgcaagc
     6001 tcttgatagg cttgattcca gttctgaatt ttttcattcg agcggatata gactgcctgc
     6061 tggtactcct ctctctcatt gacaggcaaa atggaaagca atttaatctc tgtcaatgga
     6121 taatcgcgag caacggattg aatgatagct tcgagattat tgagagcctc attcacagga
     6181 acatcctttc cgatatcatt tgtcccaatc agaagaaaaa ttttatctac tgctccacca
     6241 tatagatgag catcaaggtt ctctagtaac agtcctgtct gatagccacg aattcctcga
     6301 ttgacaatcg tctttgaagt cccaaatagc tcctgtagag gataatactc gacaatggaa
     6361 tccccaataa aaagaatgtt tggttctaca acagaaatgt gatttaggtg acgatactta
     6421 gtttgaattt tttcttgttc ctttaggagc caattttcta ataactgtac tgccacttca
     6481 ttctcctttt tctaaccagt tttccaaaac ttgataaact cctccttggc tgttggctgg
     6541 tgctagagca gtcgccacag ctttggcttt ctcatcagca ttttccatcg cataggcaat
     6601 tccagccatt tcaagcattt caacatcatt ttcactatca ccaaaagcca tgatttcttg
     6661 ggatttcaag tcccagcgct tgagtaattc ctccaagccc catgctttat gaatcccagc
     6721 ttggaggata tcaatgcaac catagccact ggatacagct cggacacggc catcaaagag
     6781 agcattgatt tcttccaaaa ccgaactcaa acgttcctca ccaacaacca tgctcatctt
     6841 gagcacacca ccaaagaggt cagatgttaa ttcatccaca aattgcatcc gttggtagaa
     6901 tttttcaatc atttctggag tcataaaact ttcaagatct gtaaaaatcg taccttcctt
     6961 gacaaaatca cccttcatcc ccgttacaac aaactggtcc tgacacgctc gacccttgaa
     7021 atgagccaaa gccttgttga caatggcgtc atcccatgtc tgagcctgaa tcaattcatt
     7081 gttttcaaaa atacgagcgc cattagcaac aaccagaacc actcgatcca ccaagggact
     7141 cagtagttgt ctcatgcggt gaatttcatt gcccgtcgca atgacaaaac gaatgcccct
     7201 ttgatccaac tgatctaaaa tcttttccaa tcgtgggaga tcaagctgac ccctagcatc
     7261 cagcaaggtc ccatccatat ctgtcgcaat taccttaatc atcatttact ttcctctgga
     7321 ttcaagctaa taccacttca atcccacatg ttcattcatt tctttatagg ctgtatcaat
     7381 tcgttcctta gtcgcttcat ctaactggtc acgatgactg ccacccctct ataaaatctt
     7441 ccaaaatata agtttggtaa tgatacaagg gatatccttc tggtgaaaag gttccctttg
     7501 gtgttcgatt gacccaagta ggatgagctt tagctgttcc gatagttgtt tttccatcct
     7561 tcttcttgat ggtgacatcc atgagaacac cacgttcagt ccacttagca ttctcttcat
     7621 ctcccataga ttcaattcgt tgattggaaa tgaagttccc catttaatag ataatgagtt
     7681 tcttatctcc atctttttca accatttcag atggttcaac aacgtgagga tgccctccaa
     7741 agataatatc cgctccccaa tcgatcatct tgtgataaag agctttttgt tcttcagttg
     7801 gttccaatcg atactcaaca cccatctgaa gcatgataat ggtgatatct gcttccttct
     7861 ctgcccgttc aatttcagcc ttcatcttat cttcgtttaa atctgaaaga taacgattat
     7921 agtcttcctt agaaatatac tgctcaattc cattgaaacc ataggaatag gctaacaatg
     7981 caaccttgat accattcact tccttaatga ccagcggagc ctgaacacgt ggttcgtgcg
     8041 tataaactcc gattggagtg attccagctt tctcaataat atcggccgtt gaaataactc
     8101 cctcaatttg cgaatccaaa atatgattat gagctaaatc cagcacatga taacctgcct
     8161 ccttaatagc atccataact tcaacaggag cattaaagag aagataaccc gctaaataat
     8221 gatccttatt aatggttcct tcaaaatcac caatagctaa atctgcttgc ttgagccaag
     8281 gagtcacata ctcaaaattt tcatgaaagt cataggtacc gtcttctttt ttagctgaaa
     8341 agaaaagtcc atcgtggtag agcaaatccc cgtgggccat aattctggca gttttttcct
     8401 cttcctactc ctgagacttt tgcttagtcc cctcttgaga aatagtatct cgtttttgac
     8461 tagtcaaggg attccttgga agctttcaaa caacaagacc aagcccattg ataaaccaac
     8521 tgctagcaag agtatcgcca caaatccctt attgctccac ttgcgataac tcctaaaaag
     8581 tttaccaagc ccttcataaa acgaaaagct aaaccaccct gatttcgatt ttgtcttctt
     8641 tgtatcttcg ttctccctac tttcttatgc aagccttttc tttttattat atcacagata
     8701 agtatttctt tcacaattga attgaacttc ctatctattt tctataaatc ctaaatgcca
     8761 taatgctttc aattcttgtc attttgtgat atcatgtaga ggaaatgaac taatccacag
     8821 tggcttattc caagtatacc acttgggctt tggcagtagc taactgcact aaacataata
     8881 taaggagaga aaatgtctgc aatagaacgt attacaaaag ctgctcactt aattgatatg
     8941 aacgatatta tccgtgaagg gaatcctact ctacgcacgg ttgctgagga agtcactttc
     9001 cccctatctg accaggaaat catcctaggc gaaaagatga tgcaattcct taaacattcc
     9061 caagatcctg tcatggctga aaaaatggga ctccgcggtg gtgttggact ggctgctccc
     9121 cagttagata tctcaaaacg cattatcgct gttttggtac ctaatattgt tgaagaaggc
     9181 gaaactccac aggaagccta cgatttggaa gccattatgt acaatccaaa aatcgtctct
     9241 cactctgttc aagatgctgc tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac
     9301 gtgcctggct atgttgttcg ccatgcccgc gttactgttg actactttga caaagatgga
     9361 gaaaaacacc gtatcaaact caaaggctac aactccattg ttgttcagca tgaaattgac
     9421 cacattaacg gtatcatgtt ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa
     9481 gatggtttac tgattcttga ataaagaaaa tcccgttgca agacggggtt ttgtgttata
     9541 atagaggcat gaaaacaaat gatattgtct atggtgtcca cgccgttacc gaagccctcc
     9601 ttgcaaatac aggaaacaaa ctctacctcc aagaagatct ccgaggtaag aatgttgaga
     9661 aagtcaagga actagctaca gaaaagaagg tgtccatttc ttggacatca aaaaaatctc
     9721 tctctgagat gactgaaggt gctgttcatc aaggttttgt tctacgagtg tctgaatttg
     9781 cctatagcga gctagattac atccttgcaa aaacacgcca agaagaaaat ccacttctat
     9841 tgattctaga tggtctaact gatccccata atctgggttc tatcttgcga acagccgatg
     9901 cgaccaatgt ttcaggtgtc atcattccca agcaccgtgc tgtcggagta actcctgtcg
     9961 ttgccaaaac agccacaggt gctattgaac acgttccaat tgcccgagtg acaaacctca
    10021 gtcaaacctt agataaactc aaggatgaag gcttctggac ctttggaacg gatatgaacg
    10081 gtactccttg ccacaagtgg aatacaaaag ggaaaatcgc cctcatcatc ggaaatgaag
    10141 gaaaaggcat ctctagcaac atcaaaaaac aggtcgatga aatgattacc attccgatga
    10201 atggacatgt tcaaagcctc aatgccagtg ttgctgcagc cattctcatg tacgaagttt
    10261 tccgaaatag actataaaaa agtttccagt catctgattg gaaacttttt tatgattaac
    10321 tatgttctgt gataaacttg taggcttctt gaccagcgat agctccatct ccaactgctg
    10381 ttgttacttg gcgaaggtct ttcaagcgaa catctccaac tgcaaagata ccgtcgactg
    10441 cagttttcat gtggttatct gtcacaatcc atcctgcctg atcttggata ttcaattctt
    10501 taacaaaatc gctaagaggg tccaatccaa catagataaa gacaccaccg aaggcttgtt
    10561 ctgtcacttg acctgttttc acattttcaa atacgactga ttctactcgg ttttcaccct
    10621 tgattttcct tactacagaa tcccatataa agctgatttt ctcattggca aaggcgcgat
    10681 cttgtaaaac cttttgggca cgaagttggt cacgacggtg aacaatggta acagtcttag
    10741 caaaacgagt caagaagagg gcttcttcaa cagctgaatc tccaccacca actaccaata
    10801 aatcttggtc acggaagaaa gcaccatcac acacagcaca gtaagaaaca ccacgactgt
    10861 tcagttcttc ttctccaggc actcccaaag gacggtgttt agaaccagtt gctacgataa
    10921 ctgtacgtgt ttcatatgtt tggtcatcag tcatcacttt cttaaaatca ccatggtctt
    10981 cgacattttc aacataacca taaatgtgct ccacaccaag attttcaagt ggttcaaaca
    11041 tcttttcagc caattcaggt ccactaatat tagcgtatcc tgggtaattt tcgatatcag
    11101 atgtattatt catctgacca cctggcagac caccttcaat caaagctact tttagattgc
    11161 ttcgagcagc atacaaggcc gcagtcatcc ctgcaggtcc agcaccgata ataatagtat
    11221 cgtacatata gattccttct ttcttgttgt aactatcttt attctaactc tttcttgtca
    11281 atcacgcaag gattatgcct tgaaaacaag aattaaactc ataaccgcaa aggataatac
    11341 tgggacaacc aagactccaa tcataatcat atcatagaga tgggcttggc gagccttggc
    11401 tgtcttatca actcccgaca tggctctcag accaatccaa atccctaaaa aaatcagaac
    11461 aaggatggtg gtcaatatca aactctcgaa atataaagaa aatagttgca gtagcatgat
    11521 ttctctcatt tctatctttt ttaaagagta aactcagcta gtccaactaa ctgagttttc
    11581 ctttatctat tatatcaaat ataagtccgt ttgtaactag cgaagaattc ttttgtccgc
    11641 tcttctttag gggtgtggat aatctcatcc ggagttccag actcgatgat tttcccctta
    11701 tctaagaaga gaatcttatc cgcaacttgg gctacaaagg acatgtcatg actgaccaaa
    11761 atcatggtct gacctgactt agcagcatct gcaatagact tttctacttc accgaccaat
    11821 tctgggtcaa gggctgaagt tggttcgtct aagagcaaaa catctggttt catagcaagc
    11881 gcacgcgcta gggcaacccg ttgcttctgt ccacctgata aatggcgagg ataatggttt
    11941 tcacggtccg aaagcccaac cttagccaac tcttccttgg caatcttagt cgcttcttgg
    12001 tcagataatt tcttgacaac aaccaagcct tctttcacat tatcaagtgc tgttcggcgt
    12061 tcaaacaaat taaactgttg gaaaaccata gacaacttac ggcgtagggc aaggatttct
    12121 tcttgagtaa ttttagaaaa atcaactgaa aaaccatcaa tctgaataga gccactgtca
    12181 ggtgtttcaa gataattgag actgcgaaga aaggttgatt ttccagctcc tgaagaacca
    12241 atcaaggcta caacttcccc tttttgaata tccaagtcca gatgatccaa gacagtctgt
    12301 cctgaaaagg atttgcttaa attcgaaatc ttaatcatta acgaaggtct cctttcacat
    12361 ctgtttgcac tgtatcaggt gcagaaatag ccatttttct ctcgatgaaa cgaccgaggc
    12421 tttcaattcc gatattgact acccaataaa caagggcaac ggagatgaag cgttcaaaat
    12481 agcgataatc agctccacct agaatctgag cttgggcaaa gacttccaca acacccgcac
    12541 taaaagctag agatgttccc ttggtcaaac cgatgaggga attaatcaag gttggagtag
    12601 ctaccaccgc tgcattagga ataatcactc gtcgataaac ttgcgctcgg gtcataccca
    12661 gactgcgtgc cgcctcaatc tcaccaggat taactgagag aatggctgca cgaatggttt
    12721 cactagcata agctgcctca ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa
    12781 tcgcattgat attgagacca gttccccatt gctgattgag ggctttcaaa gccaaaggga
    12841 ttccgtagta ggtcaacatg agttgcacca aaatcggtgt cccttttaag aaactaacaa
    12901 agaaggcctg caagggatat aaaatcttga cacgattgat cttcacaatg gcaaaaagaa
    12961 gcgccaaaac caagccaaaa agggcaccac caattgtcaa cataattgtt gttggaagtt
    13021 gttggacaat tctagggatt ccatcaaaga ccgaacgtag gctaaacagc ttgccatccg
    13081 gaatcaattg catcaagttt tggtaccaat ctgatgctaa aatcgttgta acattcataa
    13141 aaacatcctc ttctaataat gattcattct accatgcttc tgccgtcaat gaaattattt
    13201 gctacggtca gatacagact ttgtctacct actagtttat catactttga aacagggaag
    13261 ttatatattt tatctatcaa agagatagat aaaaactatt tcagtcccag ttcttcataa
    13321 gattttcgat aaccgatttg cttaacagtt ccattttcta ctaaaatggg ccgttttaac
    13381 aacataccgt cacttgctaa caactcagcc gcttcttggt ttgacaaact tcctacctta
    13441 tcttttagcc ctaattcacg gtatttgatt ccactggtgt tgaaaaattg cttcaattca
    13501 aatcctgagg tttctagcca attcaaaatg acttcttggc taggtgtttc ttccacgata
    13561 tggacggctt tatagtccac acctaattga tttaattctt gttttgcttt tttacaagtt
    13621 gaacatttgg ggtattcgat aaattctaac atgtgcttct ccttctattt gtttctatct
    13681 ttaaaatcta ctccttcatg ctccaagagc caagctttct tttccactcc tgcagcatag
    13741 cctgtcagac gcttgcctgc tcccaacaca cgatgacaag gtactaggat agaccaagga
    13801 ttgcgtccca ctgctccacc aattgcttga gcagaagcca cttgcaggtc ttgagcaatt
    13861 tgtccatagg tcactgtctg accataagga attccctgta aataggacca aactctcttt
    13921 tcaaaattcg ttccaattgg cgccaagagc aagttggata aatcctgagg ctcgccttta
    13981 aagtaatcat ctaagcaagc aataactggg tctaaaatag gatgactaac aacttcttct
    14041 atcgtttcat ctcctagtcc cctctcaaaa tgcttctgct cctgaaccca aattccatac
    14101 aaataatggt catcagctac aagtgataga ataccaattg gtgaggagta gaggattttt
    14161 acatacttct tttgcattat ttctttaatt tttgataggc caagcgttcg ccatctactg
    14221 gcaccttacc aacttgttta aaaccaagtt tttcaaaaat atgttgcata accttgtttt
    14281 cagcatgcgt atctgagcga aaatcaagat aatcaaaacc ttcaatcaag ccctctaaga
    14341 aggtttgagc aactcctttt ccctgcacat ctgctgccac agcaatacgg tgaaagacta
    14401 gatactctga ctctccagct tgccagtttc cctcataaat agcttcatag gcctcctctg
    14461 gactcttggt cacagcagca taggctagca gttctccctc ttccaaggct acgtaggctt
    14521 gccctgagat gatatcatcg ataataacat ctgcatttgg atagccattt tgccactggt
    14581 tactaccagc atctgctaaa cattttttgg catcctctat cacctgcatg atggcatcta
    14641 cttcatttgg aaaagctaaa cgaatttcca tcttttttcc tcatttctga ctagtttctc
    14701 ccatcatagc ataatttaag tctttctaca agcagttaaa acttgacttt gtatttttgt
    14761 tattttataa tctagttatc aaaactatat aaaaaggagt tgaaaatgaa aactaccttt
    14821 tcctacccaa aatgggcaga aattccaaac attaacctct atctggacca ggttttgctc
    14881 tatgtcaatc aggtctgcgc ccctatctct cctaataaag acaaaggcct aacagcatct
    14941 atggtcaaca attatgtgaa aaatggttac ctgacaaagc ctgacaaaaa aaaataccaa
    15001 cgccaacaga ttgcccgttt gattgctatc acaaccctca agtctgtatt ttctattcaa
    15061 gaaatagccc agacacttaa tactctacaa actcaagcaa gttcagacca actctacgat
    15121 gcttttgtgg actacatgaa ccaaggaatt gacccagcta accctattat ccaaaccagc
    15181 tgccaaaccg ttaaactcta tcatcaaact ctagacttaa tcgatcatac tcaagaggag
    15241 gtaatccaat gaacactagt cttaaactca gcaaacaact cagttttgga gaggagattg
    15301 ctaatagcgt gacccatgct gtgggtgcag tcatcatgct tatcttgctg cctatttcat
    15361 ccatctatag ttatgaagca cacggatttt tatcctctat cggcgtttcc attttcgtca
    15421 tcagtctctt tctcatgttc ctatcatcca ccatttatca ctctatggcc tatggttcga
    15481 cccacaaata tgttttgcga atcattgacc attctatgat ttacgttgcc attgccggct
    15541 catacacgcc cgttgtcttg accttgatga ataactggtt tggctatctg attattgtca
    15601 tccaatgggg aacgaccatc tttggtattc tctataaaat ctttgctaaa aaggtcaatg
    15661 agaaatttag ccttgctctt tacctgatta tgggctggtt ggttctggct atcattcctg
    15721 ccattatcag tcaaacgaca cccgttttct ggagtctcat ggtaactggc ggactctgtt
    15781 atacagttgg agctggattt tatgccaaga aaaaacctta tttccacatg atttggcatc
    15841 tctttatcct agctgcgtcc gcacttcaat acatcgctat tgtttattac atgtaaaaaa
    15901 gttgagaaat tcaatctcaa cttttttctt tacacatatt gataaagtac tggtgcaagc
    15961 gcacatcatc agtcaattct ggatgaaaag aacttaccaa catatttttt tcttgggctg
    16021 caacaatttg attgttcact gttgctagaa tttctacacc ctcaccaaca ctactgataa
    16081 tcggaccacg gataaaggtc attggaatct tgccaactcc cttacattct gcttccgtgt
    16141 agaaacttcc taattggcgc ccataagcat tacgctcgac caccatatcc atagttccta
    16201 gatgactctc tttctgagaa gtgatttcct tagccagcaa aattaagccc gcacaggtcc
    16261 caaacactgg taagccagat agaatgcctt ctcggatggg aagtagcatg ttctggtcac
    16321 gtaagagctt gcccatggtt gtagactcac caccaggcaa aatcaaaccc gacaagtcac
    16381 tctgatcttg ctgaaaatca tctagatttc tgagttctac actctcgaca cctaattgat
    16441 ctagcacttt tgcatgttct gcaaaggccc cttgcaaggc caatattccg attttcatct
    16501 attttcctcg ttcagccatg agaatttgga tttcattttc attaatacca accatggctt
    16561 ctcctaaatc ttcagagatt tgagctagga tttgaggatt acggaagtta gtcacagcct
    16621 taacaatggc actcgctcgt ttaacaggat ctcctgactt gaaaatacct gaaccgacaa
    16681 agaccccctc tgcccctaat tgcatcatta acgcagcatc tgctggcgtt gcaacacctc
    16741 cagcagcgaa atttacaact ggcaattttc catgttcatg aacatattgg accaattcta
    16801 cagggacttg caaatccttg gcagcaacat aaagctcgtc ctcacgtaag ttttgaatgc
    16861 ggcgaatttc ctgattcatc atacgcatat gacgaacagc ttggacgata tcccctgtcc
    16921 ctggttctcc tttggtacga atcatggaag caccttcagc gatacgacgc aaggcttcac
    16981 ccaaatcctt agcaccacag acaaaaggaa cttggaattc tttcttgtcc acatggaaac
    17041 ggtcatcagc tggagataga acttcactct cgtcgatata atcaatttca atagcctcta
    17101 aaatctgagc ttcaacaaaa tgcccgattc tgaccttagc cattactgga atactaaccg
    17161 cttcttggat ttccttaatc atctttgggt cgctcatgcg ggaaactcct ccagctgcac
    17221 gaatatcagc cggaattcgt tccaaggcca tcacagctgc cgcaccagca gcttctgcga
    17281 tacgagcctg ttcaggattc tgcacatcca taataacacc acccttgagc atctgtgcca
    17341 agtttttatt tagttcataa cgattttcag tcatttgttt tatcctcatc atttgtattg
    17401 gtagctacct tttcatttta agtcagaaca gaatgaagca caagataaaa aaactataat
    17461 tgtatgggga cagattagct aaaaactatc tgaccttaac ttaaggccag atagctcatt
    17521 catttttatt tttcagccgt aagggcagcc attgtgatgt agttgtatgg tttgttgaag
    17581 tgtggcaaga agaagaggtc tgtcaatgcc aatttatcaa ttgtcacatg ctcttggata
    17641 gcaagtgaga acatgtggat tcccatgcta attgcaatat catgtgaaac catttgggca
    17701 ccaagaattt cacggctatc tttgtcaaag acaatcttaa ttgctacttc atggttgtca
    17761 tgtttcatga attctggttt ttgaagatcg ttaaagcctg tttcagttgc gttgtaacca
    17821 gcagctttcg ctttttcaag agtcaaacca gttgaaacca tgtgaagacc gtagattgag
    17881 ataccatttg aaccttgaac accgattcct tccaattcat gtccacaagc gttgtaggca
    17941 ccaacgatac cagtgcgaac agcatttgaa gcaagagcga tatagcttgt atctttacga
    18001 gcattgtcat aaacagtcgc acagtcacca acagcgtaaa cgcctgggat agatgtttct
    18061 tgtttcttgt ctacaaggaa ggcaccgttg cggaagagtt cgatcttacc atctgcaagg
    18121 gctgtgtttg gacggaaacc aactgcaagg ataaccatat ccacgtcaaa gctttctttg
    18181 tcagtaatca agcgttcaac tttaccgtca ccttcgattg ctttaacagt ttgacctaga
    18241 gccaagcgga tgttgtgatc ttccaagttc ttcgccatca tttgtgtgaa gtctttgtca
    18301 tagtaaccgt tcaagacagt atcaacgata tcaacaagga caacttcttt tccaagacgt
    18361 tcaaaggctt cagcaagttc aacaccgatg taaccaccac caacaacggc gatacggtcg
    18421 aggtgttggc tcttgtcaga aagtttattg ataacttctt cagcattttg gtacaatttc
    18481 acgaattgta cgttttcaag agttgcttta aattcgcggt ttcctttaac aatttcaaca
    18541 ccttcgattg gtggcaagat tggtgtagaa cctgtagcga aaatcaattt ttcgtatgat
    18601 tctttgtgct cttttccttc aacttccgct gtaactactt tgttatcata gtcgattgaa
    18661 agaacaggtg agttcatgta aactttagca cctttagctt ccaatttttc tttatcagaa
    18721 tagaacaagc cttcagcacc gtcaatttgt tcaccaatcc aaagagccat tccacatcct
    18781 aggaaagaga tgttagagtt ttggtcaaat acaacaattt cgttctcatt tccaaaatta
    18841 tccaacatgg tattgataca tgctgtacca gcgtggttag caccgactac aacgatttta
    18901 ctcataaaaa tttcctgcct tcattctaaa tttaccttac tagtatacca tttaccgtta
    18961 gcgtttacaa ggggggtact attatttcag cattttttat caaaaataat tccccattta
    19021 tcctgttttc aagcctcatg aattttatga gcatatttct tgactttttc caaattttgt
    19081 ttgtgaaaat tctaacttta tggtattata ataacatgaa aatgaaatgt aagggcttca
    19141 atttagatga ttatttgata ttacaactta ttttctataa gagaaaggag ttggtagctt
    19201 gactcttcgt tcacattctg aacggctaat ggggactact atcactattt cattagtgga
    19261 tgagcaagcc gatatctttc tccaaaaatc ctttgacttg ctcaaagaac ttgaataccg
    19321 cttcaacgcc aatagtcaag aatctgagtt gatggaaatc aattatcaag caggaatagc
    19381 ccccgtcacg gttcatccag acctgtttga gctgatttca cttgggttag agcatagcct
    19441 agcgctctct agccacctca atatcagcat tggtccctta attcaaacct ggcgtatcgg
    19501 tttttcagat gccaaggtcg cccagcctca agaaattgaa tcggtgctgc ctctaatcaa
    19561 tcctcatggt atcgagttag attcttctac ttctactgtg tttttaaaac agaaaggaat
    19621 gaagatcgat ctaggttgtt tagccaaagg atacagtgcg gataaggttg cccaatttct
    19681 taggaaagag ggggtgactt ctgccttgat caatctggga gggaatatcc tgaccattgg
    19741 aaaaaatcag gcaagagggg ataacccatg gcaaatcggg attcaagacc cagccaatcc
    19801 taggggaaat catttaatga ccatccctgt tgtcaataaa tctgtcgtga cttcaggcat
    19861 ttatgaacgt cacctgaccg tcgatggaca agattaccat cacatttttg acagtcaaac
    19921 aggatatcct gttgaaacgg aactagcgag tctaacaatc atctctgata aatcagtcga
    19981 tggcgaaatc tggacgactc gactctttgg agaaagacct gcttctatcc tctggcaagt
    20041 cgaaagtttg gagggcatcg aagtcatcct catcgataaa gaaggccacc taagctgttc
    20101 ttcaggaatt cctactctat agagacaact gtttcaatgg aattttaaaa ttgtattatg
    20161 taaaaagaga aaggaaatct catgttaaaa cttattgcta ttgttggaac aaattcaaaa
    20221 cgttctacaa accgtcaatt gcttcaatac atgcaaaaac actttgctga caaagctgaa
    20281 attgagcttg ttgaaatcaa ggccattcct gtcttcaaca aaccagctga caagcaagta
    20341 cctgctgaaa tattggaaat tgctgctaaa atcgaagaga cagatggcgt tattatcggt
    20401 actcctgagt atgatcactc tattccagct gttttgatga gcgctcttgc ttggttgtct
    20461 tatggtattt acccactttt gaacaaacca atcatgatta caggtgcttc ttacggtacg
    20521 cttggttcat ctcgtgccca attgcaactt cgtcaaatct tgaatgctcc tgaaatcaag
    20581 gcaaatgttc ttccagatga attcttgctc tcacactctc ttcaagcatt taacccaagt
    20641 ggcgacttgg ttgaccttga tgttatcaag aaattggatg ccatctttga tgacttccgt
    20701 atctttgtaa aaatcacaga aaaattacgt aatgcacaag aattacttcg caaagatgct
    20761 gaagactttg actgggaaaa tttgtaagat aggagaccaa aaagaatgaa atttgttgga
    20821 cttgttggat caaactacga tcaatcatat aaccgtaagc tcttggaatt tatccgtcgc
    20881 tacttcaaac tcaaatttga attagaagtt cttgaaattg acgaagttcc aatgtttaac
    20941 caagatgaaa aatgggatga aagtttccaa ttacgttatt tatataacaa aattactcgt
    21001 gcagatggtg ttatcattgc tactcctgag cataaccaca ctatctcagc ttcactcaaa
    21061 tctgtacttg aatggctttc atacgaagtt catccatttg aaaacaagcc tgttatgatt
    21121 gtgggtgcat catactatga ccaaggaaca tcacgtgctc aagttcacct tcgtaaaatc
    21181 cttgatgctc caggtgttaa tgcctacacg cttccaggta acgaattcct tcttggtaaa
    21241 gctaaggaag cttttgataa caacggaaat atcaccaacg aaggcactgt taaattcctt
    21301 gaaacttgct tagataactt tgttaaatac gtaggagtcg tttcgaaatt gaaaaaacca
    21361 aaaccaatcg aatcagaaga cttggattgt ggaaaaccaa tcgctacaac catcacagaa
    21421 gttgaccctg acgatccaga atgggtagaa aaagttgcag caatcactgg tgctgtttct
    21481 ggtgatacct atgtcaaatt ggaccacggt atcctaacag ttaaccaaat tgatatgttc
    21541 ttgaaagcta tgccatttga attgacatac gctgacgata acaaccaatt cctctactac
    21601 aacaacgctc accaagatcc agacactatg ttcgctaaac gtgtaccacc tcaatcaggt
    21661 agccgtatgt cgactgttca tggttctctt ccaccagcac gtatgaagaa cgtagagtgg
    21721 gttatcggaa cacttcgcaa cggaaaccaa gaatacgtcc gtacgatcgt tccaggttct
    21781 cctgcaggtg ttatcaacac tcacaactac caagcaatgt actatcctga tggatcatac
    21841 gctggtatca atgaaatcgt ctttaacttc caaccatggc ttgactggta cctaaaagag
    21901 actggtcaac gtttggtggg tggtagcgga ccatttgctc ctgctgccgg aggtcatgga
    21961 gacgccgatg ctacttctgg cgcttctgat tcaggggatg ctggaggcca cggtggtgac
    22021 gcagacgcta cagccggtgc aagttactaa tgatagtttt taggaaccat tatggttcct
    22081 tttttagcga aaaaagacta gcaaacacaa actgctagtc tctttgttat cgtttcatct
    22141 atctttgtta aaagaaagaa tacatattat gaatttggat catcaagact acggccatgt
    22201 aatccttttt cacgttgtac ttggcgtagt ttttctggtg taacatcgtt tccttcttcg
    22261 tccacaattt tgattccttc aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac
    22321 tcctcacgta gtttggcttg ttccactttt tcttctggtg ttaagccttc tgtttttttc
    22381 tttttagcaa gctcattgat acgagcaatt tttttcggat ccatttcttc tcctctgtaa
    22441 taagataaag tccgtttatc aaattttatt tagtgttaat ttggttaaaa caagcaaact
    22501 tagctgcttt cttggttagt tgtgacaaga ttgccaaacg attttgacgg acagcctgat
    22561 cttcagccat taccatagta ttttcaaaga aagcatcaat gactgggcta agcgcaaaga
    22621 gttgtttcaa ttgctgactt gcaggtcctg ataaaacgag tgtttctact gcttctgcca
    22681 aagctttttc ttggtcattc tcaaatagtg ctgaatcaac cgtagcaacc ccttctgcct
    22741 tctcagccag gttaaaggca cgagaaagtg attcaacaga tggtttaaaa tcttcttcct
    22801 tgcttacttc tacgagagca cttgctgctt ccaacatatc tgccacaaca aagtttgaac
    22861 ctgcaagaac tgcttctttg atatcttttg gagtagagcc catcatctta tcaacacgag
    22921 ccttgataaa gtccataacc tctgctttat tttcataagt caaactgtca aatttcaatg
    22981 cataaaggct atcaatcagc tcatccatag caatgtgcca accaaaggca tccaagatac
    23041 gaaccacacc ttgagttgca cgacgaaggg cataagggtc attagaacct gatggaatca
    23101 atcctactga gaagaaactc aaaatcgtat ccaatttgtc tgcaatggct agaactgcgc
    23161 cgaccttgct ctctggaagt tctccttcag ctgatgtagg catgtagtgt tcacgaatag
    23221 cagctgccac cgctggagtt tcaccagcaa gaagggtgta tttttcaccc ataattcctt
    23281 ggagttcgtc aaattcacca accatacctg tcaacaagtc aaacttgtaa atggctgctg
    23341 cacgagcaag gtcaactgtt tcatccactg acaaaccagc tttttctgcc aaaagtacag
    23401 tgatttgacc cgtacgaatc atgtgttcac gaagggaacc aatcttctca tggaaggtga
    23461 cattgtttaa tttttcaaca agatctgaaa tcaccaattt ttggtcttca cgccagaaga
    23521 attctccgtc ttccaagcgg gctaccaaga ctttttcatt tcctttgatg acatttttca
    23581 aacgctctgc gtttccgtta cgaacagaaa tgaagtttgg caagagtttt ccatcttgat
    23641 cacgaacaac aaagtaacgc tggtgttcct tcatagaagt caccaagact tcttctggaa
    23701 cttcaaggta tttagcatca aaacttccca tgaaggcagt tgggtattca accaaattca
    23761 agacttcatt cagcaaatcc gcatcaattt cgatacgtac accatgtttt gcctcaattt
    23821 ccttgatttg gtcaacaatc atttgctcac gttcacatgg atctgcgatt acaaactgct
    23881 tacgaaggtc ttcttcatag ctcaatgctg actgaatttt ggtttctttc cccaagaaac
    23941 gatggccacg gctcacacga cttcccttga tatcaaggaa atccaagtca aactcttgct
    24001 catccaagag aacagttaaa gtgtggacag ggcggatgta ttcaaagcta tttccagccc
    24061 agtgcatgct gacagggaaa gtcaatgact tcaagacatc tacaacacca ggaacaatgg
    24121 cttcaactgc ttgaccaact tcttccttag tgacatagac atattcttca cccttgattt
    24181 cacggaattc gatatcttca acagtcaagc cttttccacg gacaaatcct tgagctgctt
    24241 tggtgaagtt tccatcacta tccaaggcaa ttttctttgc tggtcccttg aaatcttctg
    24301 tcaaatcaga ctgtttgtct gataaaccag tcacacgaac agccaaacga cgtggtgttg
    24361 agaaggtttg aatggcttca aaagacaggc ggttttcctt gaggaaggct gccatttttt
    24421 cgcctagttg tttttcactt ggtgtgacaa cataggctgg taattcttca agaccgagtt
    24481 ctactaataa gttttttgtc atgttttttc tccgaaaagt atctttttat tttccagttt
    24541 gccttatgtg attggcacgc aagcaaccaa cttcgttgtt tcattgctaa aattggagcc
    24601 aaaagtctcc aattttgcct agtatcctta gtttcactaa ggataccttc atcactgcgg
    24661 caactggctc agggctcact ctgttcgccc attttcgtaa tttgtcactc tctttattct
    24721 gcgtcttctg ctaaaagttt aactcgtgtt tcttcatcca aaagtgggta acctaggcgt
    24781 ttgcgttctg caacaaaggt tttggctaca acacgggcca agttacggat acgagcgata
    24841 tagcctgcac gctctgttac agatacggca ccacgcgcgt caagcagatt aaaggtatgt
    24901 gaacatttga gaacatagtc ataggcaggg tgtaccaagc cttcttctaa tgcacgacca
    24961 gcttcttttt caaacttatc aaagttttca agcaacattt cttggtccga aatttcaaat
    25021 gaatattttg agtgctcata ctcaggctgg ataaagattt ctccgtattt tacaccatca
    25081 gcccactcga tatcatagac agagtctact tcttgaatgt aagaagccaa gcgctccaaa
    25141 ccataggtaa cttccgcagt cacagggcca gttgccaatc caccgacttg ttggaaataa
    25201 gtgaactgag tgatttccat tccgtcaagc caaacttccc aaccaagacc agctgaacca
    25261 gttgatgggt tttcccagtt gtcctcaaca aaacgaatat cgtgctccaa aggattgatt
    25321 cccaattttt ccaaagactc aaggtaaagt tcttggatat ttgatggaga aggcttcatg
    25381 accacctgga attggtggtg ttggtagaga cggttagggt tttccccata acgaccgtca
    25441 gcaggacgac gtgatggctc tacataagct gcattccatg gctcaggtcc gatagcacga
    25501 aggaaagtgt aaggactcat tgttcccgca cctttttcat tatcataagc ctgcataagc
    25561 atacaacctt ggtcattcca aaattgttgc aaagtcaaaa taatttcttg aaatgttaat
    25621 ttcttagaca ttgaatactc cttaataaaa aataattact tgcgacacga gtctgcctcg
    25681 tcgatcatac gaggcaagac gagttagtac tgcgtctagc tcaggcactc tagtgctgag
    25741 cgtggggcag tccgactgta aggaggtttc tgccactgat gcagtgaaat gttaatttct
    25801 cagacattga atactccttt agtttttata tttctttttc aattaatttc tgctgaacaa
    25861 accaatctaa caagggaaaa gttttttctg tatttgccca taaatgataa gaatcaaaga
    25921 ccgcttgtac actacctaaa ttttctacca acttatctac tgtcaaaaag ctgcgccagt
    25981 attcataaaa aatacttgca tagttcttat cataagtcga agaaccaaaa tcattcaatg
    26041 aatgccaacc atacttcttc tgaaaaagtt ctacgagaga ttgattacaa attttttccg
    26101 cttgaaattc ctcttctgtc aagaaatact tgcgactaat atattcaacc atcccctctt
    26161 cgaaccagat ataagagtca taaccatcaa aatcatctaa aaaatgctcc gaccaatgag
    26221 ctaactcatg tcctacaatc tgtaagagga aattttcaga taaagaatga tagtggcttt
    26281 ctattgcttg agtttgctca gaacactcgt agtccatcaa ctgatacaaa tacaactctt
    26341 tccaaacagc taaatcaggc gtcataacca ttcgtctatt atttgtatag gctggaacag
    26401 cactttccct aataatctgt gtagcagcat taagatctga ccaaataacg gcttgcggta
    26461 aatcacagac tgcaagttca ttctttaaaa aagattgata atctttcaac ttttcagtat
    26521 ttcttactac aaaatcacga aatgtagcta gttgactatc gtcttttaca agataaaggt
    26581 tgtccacggc tctcctttct ttcacacaat agactgaata agcaaaagaa ccacatctga
    26641 caagcctagg ttgatttaac ctaggggcgt cagaaacgcg gttccaccct aatttattac
    26701 ttcattgttt ttgaaaatac tacagaaagc gccagcccat tattttgccc tacttggctc
    26761 ccactgtccc aagctcgctt gaagaacgcc ataagacttt ctttcctgct gactattata
    26821 tcaaaaatta gaataatgta caattctttt tatgattttc tagaaatcca catcatcaac
    26881 tcgtggagca cccaattgaa cagcaatcgt ttttaaggtt tctctctcct tatgactcag
    26941 ttcaattcca aagcaatcaa gattagcctg aatacgagag attgtgatag attttggaag
    27001 tggtaaaaat ccttctgcca agctccaggc caaggctatc tgagcaaccg attttccgtg
    27061 atttgctgct atttcttgga cttgcttgct atcaaacagt tctccttgtc caaaaggccc
    27121 ccaagcttcc aataaaattc ccttttcacg acagtaagct acgacttgat cttgatacac
    27181 acctggcgcc aagcgaactt gattgaccgc aggaacgata gttgcagttt caagcaaggc
    27241 atccaaatga tggggaagaa aattgctaac gccgatagca cggattttcc cttcttgata
    27301 gaggtcttcc atcgctctcc aaacttccgc attgcgagtt ttccatgcgt cattttctct
    27361 gagcggtttt gggttcggcc aatgaatcaa atacaaatcc aaataatcca agcccagttt
    27421 ttctatagat ttttccaaag cttgacgagt ttgctcatag gtttgctgac tattccaaag
    27481 cttggtagtt acgaacattt cttcacgtgg aactccgcta tctttgattg cttgaccaac
    27541 actttcttca ttctgataaa tcgccgccgt atcaatatga cgataaccag ccttcaaggc
    27601 ttctaacact gcacgatagg cttcttctcc atccttagcc ttaaaagttc caaatcccaa
    27661 tactggaatt tctactccat tatttaattg ataggtattc atatgcttct ccttctattt
    27721 tattcatcaa ttatagcata aaacattttt taagtagtac tatcttctgt aaaaaataag
    27781 tctgtcaaat atctaacaga cctatttttt cttgcttatt catcacgact atagtacagc
    27841 tcatgagctt ttaggcgagt attgagcatc tctggtatgg tcacaaaggt ataaccttga
    27901 tttttcaaat actcaatgac ccttggcaag gcattgactg tcggactgtg aatatcatgc
    27961 atcaaaacga tagagccgtt agctacttga tgctgaattt ctgtcaaaat agatgcttca
    28021 tttttactct tccagtccag actatccaca tcccacatga taaagctcaa atccaagcta
    28081 ttgcgaatat catctgtaat agcaccataa ggtggacgca tgagtttaga actagaaccc
    28141 agcactttag ttagcacatc ctcagtatca gtaatctgct ttttagcttc atcaagagag
    28201 agttgcgaga gaatcggatg gctccaacta tggtttccaa caacatgacc ttcagatttt
    28261 atcctcttca ccaagtcctc attcccagaa acatttttcc caagcacaaa gaaagtcgct
    28321 ttaatatcat atttagctag ggtctctaat acctgcgggg tcgttgctgg atttggacca
    28381 tcatcaaagg ttagagcgac aactttttga tgtttcttat caaagtaaga ttggtacaag
    28441 gccgcatctt tttcgagtaa gtacgaagat tggataacat caaagaaagc agatactggc
    28501 aaggctatct cttctaaatt ttcaaccaca ggacttggat aaaggataat ctgactatcc
    28561 ttgtaatcaa aattccatgc agacaagtct tggtcagaga agttttttac aatctgctca
    28621 ctctggtctt gctctatttt tttatcctct atgaaggagg tcaactcttt tatcagctgt
    28681 tccttagcct tactagcatc tgaaaacagt tggtcaagtg taaaaggttg cccatcttct
    28741 gttaagtgaa cctttcctag actggtcttt tcagtctctt caatcttaaa agcaactaaa
    28801 tcatagattt gtttggtcac attacgatta acgactccct ttaaacctga ctcttcttgc
    28861 tctgtatagt agaaaacaag attgtcctta ctttctagct tgtccttaac atcttgattt
    28921 atcagctccc taacagagga aatcactttc tccccttgga gaggataata ggcaatcact
    28981 tcggcttgcc cctgacgaaa atgctccttc tgatttccct cactcaattg atcatctttc
    29041 tcttttttga gcgattcaat cttttgctca aaactttttt gctggtagat cttaaaagca
    29101 ataaatccgc ctaataggca aatagaaatt gctaaaatac caatcaaagc caa
//
LOCUS       DBEJZJ010000025        28161 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000025 DBEJZJ010000000
VERSION     DBEJZJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.25"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(74..304)
                     /locus_tag="ACL3R8_001386"
     CDS             complement(74..304)
                     /locus_tag="ACL3R8_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR1314255.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(314..1555)
                     /locus_tag="ACL3R8_001387"
     CDS             complement(314..1555)
                     /locus_tag="ACL3R8_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR1314256.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(1577..1729)
                     /locus_tag="ACL3R8_001388"
     CDS             complement(1577..1729)
                     /locus_tag="ACL3R8_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314257.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(1750..2028)
                     /locus_tag="ACL3R8_001389"
     CDS             complement(1750..2028)
                     /locus_tag="ACL3R8_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR1314258.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2021..2284)
                     /locus_tag="ACL3R8_001390"
     CDS             complement(2021..2284)
                     /locus_tag="ACL3R8_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR1314259.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(2386..6777)
                     /locus_tag="ACL3R8_001391"
     CDS             complement(2386..6777)
                     /locus_tag="ACL3R8_001391"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR1314260.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(6881..8962)
                     /gene="fusA"
                     /locus_tag="ACL3R8_001392"
     CDS             complement(6881..8962)
                     /gene="fusA"
                     /locus_tag="ACL3R8_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR1314261.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(9387..9857)
                     /gene="rpsG"
                     /locus_tag="ACL3R8_001393"
     CDS             complement(9387..9857)
                     /gene="rpsG"
                     /locus_tag="ACL3R8_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR1314262.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(9877..10290)
                     /gene="rpsL"
                     /locus_tag="ACL3R8_001394"
     CDS             complement(9877..10290)
                     /gene="rpsL"
                     /locus_tag="ACL3R8_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR1314263.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            10707..14549
                     /gene="spuA"
                     /locus_tag="ACL3R8_001395"
     CDS             10707..14549
                     /gene="spuA"
                     /locus_tag="ACL3R8_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR1314264.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(14649..15698)
                     /locus_tag="ACL3R8_001396"
     CDS             complement(14649..15698)
                     /locus_tag="ACL3R8_001396"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR1314265.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(15969..17777)
                     /gene="glmS"
                     /locus_tag="ACL3R8_001397"
     CDS             complement(15969..17777)
                     /gene="glmS"
                     /locus_tag="ACL3R8_001397"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR1314266.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(17969..19348)
                     /gene="bglA"
                     /locus_tag="ACL3R8_001398"
     CDS             complement(17969..19348)
                     /gene="bglA"
                     /locus_tag="ACL3R8_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR1314267.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(19448..21301)
                     /locus_tag="ACL3R8_001399"
     CDS             complement(19448..21301)
                     /locus_tag="ACL3R8_001399"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR1314268.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(21314..22573)
                     /gene="rseP"
                     /locus_tag="ACL3R8_001400"
     CDS             complement(21314..22573)
                     /gene="rseP"
                     /locus_tag="ACL3R8_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR1314269.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(22595..23398)
                     /locus_tag="ACL3R8_001401"
     CDS             complement(22595..23398)
                     /locus_tag="ACL3R8_001401"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR1314270.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(23407..24165)
                     /locus_tag="ACL3R8_001402"
     CDS             complement(23407..24165)
                     /locus_tag="ACL3R8_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR1314271.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(24396..24968)
                     /locus_tag="ACL3R8_001403"
                     /pseudo
     CDS             complement(24396..24968)
                     /locus_tag="ACL3R8_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            complement(24949..25947)
                     /gene="ruvB"
                     /locus_tag="ACL3R8_001404"
     CDS             complement(24949..25947)
                     /gene="ruvB"
                     /locus_tag="ACL3R8_001404"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR1314272.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            26081..26173
                     /locus_tag="ACL3R8_001405"
     CDS             26081..26173
                     /locus_tag="ACL3R8_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR1314273.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(26988..27404)
                     /locus_tag="ACL3R8_001406"
                     /pseudo
     CDS             complement(26988..27404)
                     /locus_tag="ACL3R8_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(27416..28109)
                     /locus_tag="ACL3R8_001407"
                     /pseudo
     CDS             complement(27416..28109)
                     /locus_tag="ACL3R8_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         8266 a         6628 c         5342 g         7925 t
ORIGIN      
        1 cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
       61 cagatttagg aaattaactt cctcgtctcc aaaaaatagc taaaacaatc atggctccta
      121 aaatcgctgg gataatagct gttcctgata aaactggccc ccaagttcca aagagcaagt
      181 gacctagaaa ggctccgatc caaccgagaa acatttttcc aaaacatccc attcgctctc
      241 cacgattggt catagcacct gctaaaaatc ccactaggag accaacgaac atacttccta
      301 acatattatc tccttaattt gcccaattcc cattacggaa aagaggtacc cgcgttccat
      361 cctcacgaat accatcgata tccatttggt tagaaccaat cataaagtct acgtgaacat
      421 ctgaacggtt aagccctgca gcttcaagct cctcttcgct catctccgct ccatcaacaa
      481 cgctagtcgc ataggctgca ccgatagcca agtggtttga cgcattttca tcgaaaaggg
      541 tgttaaaaaa ggtaatgcct gactgagaaa ttggacttgg atctggtacc aaggcacatt
      601 cacccaaggc acgcgcaccc gcatttttaa agacaaggtc tttcataacc tgatcaccct
      661 tctcagcagt gatatctacg atttgtccat ccttaaaggt caccttaatg ccttcaatga
      721 tatttccgtt gtagctaagc ggttttgtag aagtgacata accatctgca cgacggaagt
      781 caggcgctgt gaagacctct tctgtcggca tatttggcaa gaattcttcg ccctgtgcat
      841 tgacagcacc agctgattcc caaacgtggt tctttggcaa accaagtgtt aaatctgttc
      901 ctggcgctgt gtagtgaagg gctgaaaatt gctccttatt aagcatatcg gccttgctct
      961 tgagaatggc tgcatgttcc tcccaagcct taacaggatc tgcttcgtag acacgacaag
     1021 ttttgaagat ttgatcccaa aggaaatcaa ctgcttcttc gtcgctcgca gcatttggga
     1081 agactttctt agcccactca agtccagcag cggctgctac agtccagcta accttgttag
     1141 attgagttgc gatacgcata ggcttcatgg caagtcccat agctttagca gaagctgaaa
     1201 gcttgtcagc gtccactccg ttcaaggcac ctggatcaga tgaacgaacc ccaagacggc
     1261 tagccttgtt ctccaaaaga tagttcatct cagcaatctt gtattctggc acattgtcca
     1321 aacgctccat cggggcatgg aggaatttct cacggttaat cacatcatct gtccactgaa
     1381 cgatgacctc atgcgcaccc aaggcataag cttctttcac gattagatgt gccaattcac
     1441 gttgctccac atcaatagag agagccaaag tgtgaccagg ttgcacgtta attccgttcg
     1501 caaccaacaa tttcgcatat tttcctagat tttctttaaa atttggtaaa accattctgt
     1561 tttctctttt ctatttttat ttttctttca aagcagaaaa gattcctgct aaagcaatag
     1621 cacctgacaa gagtgctgtc gatagaagaa ttgtacgatc agcaagttct aattgatatt
     1681 caaatacctt cttagccggc ttatcttccg caaatattct tagtttcatg agaaccccct
     1741 taaaatagat taaaataaat cactgtgact gcctgtcctc agcaaattta aaatcaattc
     1801 cgacttgtct actttataaa ccaaaagcca atctggctgg gtatggcatt cacgaactcc
     1861 ttgaaaatgc ttggatgccg tcaatgaatg atcacgatat ctggcaggat gttctttttc
     1921 ttgaaccaga aaattcaaaa cttcttctaa taattctgcc ttcaaaccac gcttcatagc
     1981 caacttaaaa tcttttttaa actgtttatg ataacgaatc ttaagcacgt aagtcctcca
     2041 tcaaatctga gactgattca aaagactggc tcatattacg attttggtct aaatccgtta
     2101 acgcttggag caacttccga ttttcgtcta gtctaacatc aaaaggtaat ccctgatatt
     2161 gaattgcctg acgaaggaaa atattaatag ctgttgtcat atccattccc agattactaa
     2221 acacctgttg ggcctgctcc ttaacctcac tatccagacg gatgcttata ctcatctttg
     2281 acatactctc accctctttc catagactat tttaacaaaa aagaaagcta atgtaaatct
     2341 attggatata cgttagcctc ttttaataga ttattaagca attttttaaa acaactcatc
     2401 aaacaaactc aactggttat cctctggcat atttccaaga atacccatct catccatctt
     2461 ttcaaccaag gttgatgaga gtccaccacg cttgcgtagt tctgttttag agaggaattc
     2521 tccctcttca cgcgcccgca ccagttgctt ggcaacgttc tctcccagac catccattgc
     2581 tacaaatggt gggataaggg tatccccgtc gatgaggaac tctgtcgcct gactacggta
     2641 gagatctaat ttaccaaact tgaaacctcg ttcccacatc tcattgacaa tctcaagagt
     2701 tgtatagaga tcgatttcca cattagaggc ttcattgttc ttccgttttt cagagatttc
     2761 ttccattctg cgcttgatga cctccaagcc cgcacccatg gtcttgatat caaaagcctt
     2821 agcacgaatg gagaagtaag cacagtagta ataaatagga tggtgaacct tgaagtaagc
     2881 tacacgcaag gccatcataa cgtaggctgc cgcatgggcc ttagggaaca tgtacttaat
     2941 tttcccacag gattcgatat accactctgg caccttatta gccttcatgg cttcgatata
     3001 gccatttctc tcctcttctg aaatctttag ccacaaaccc ttacgtaccc gttccataat
     3061 ggtaaaggcc atcttaggtt ccagacccgc atgcatgagg taaaccatga tgtcgtcccg
     3121 acaaccgata acagtcgata ggtccgctat tccttgctta atcagatcct gagcattccc
     3181 caaccaaacg tcagtaccgt gggacagacc agacagctga agcaattccg caaaggttgt
     3241 cggatgggtt tcgtctacca ttccacgtac gaaatttgtt ccaaactctg gaatccccaa
     3301 catacccgta ggcgttccaa tttgttcagg tgttacccct agtacatcag tcccagaaaa
     3361 gagtgccatc acgccttcgt catccatagg aattttatta gggtcaatac cagacaaatc
     3421 ctgaagtttt cgaatcatgg tcggatcatc atgtcccagt acatcgagtt tgaggacgtt
     3481 ctcatcgata tcgtggaagt taaagtgagt ggtctgccat tcagccgtga catcatctgc
     3541 tggatactgg acaggcgtaa aatcgtagac atccatgtag ttcggaataa caacgattcc
     3601 ccccgggtgt tggcctgttg tccgcttgac acccgccgct ccttgagcga ggcgttctac
     3661 ttctgcatca cgataaaact tgccataatc tcgctcgtaa cccttgacaa atccataggc
     3721 agtcttggca gctaccgtac caaccgttcc cgcacggaag gcatattctt caccaaagat
     3781 atcacgcaca tccaagtggg cgctaggctg atcttctccc gagaagttca agtcaatatc
     3841 aggaacctta tccccatcaa aaccaaggaa ggtctcaaac ggaatatcct gtccgttttt
     3901 actgagtttg tgaccacagt ttggacagtc cttatggggc atatcaaatc ctgaaccgta
     3961 cgaaccatct gtgataaact cactgtactg acactgacca cagacatagt gaggagagag
     4021 aggattgacc tccgtaatcc caatcatggt cgcaacgaaa ctagatccga cagacccacg
     4081 agaaccaacc aaataacccc gttcattaga acgttgcacc agcatctgcg atgccagata
     4141 aatcacagca aatccattcc ccagtatgga tgttaattct ttttcaatcc gcaaatcaac
     4201 aatatctggc agcggatttc cataaatctc aaaagctttc ttataggtca actcagcaac
     4261 tgtttcttca gccttgtcga tgaaaggcgt atacaagtca cccttaacga cttcaacgga
     4321 ttcaaatatt tctgccaagg cattggtgtt ttcaataacc agtttacgag ccagttcctc
     4381 tcccaaaaag gcaaattcat ccaacatctc attagtcgtt cgaaaatgag cctttggaag
     4441 tggtgctggt tgggcatgtt caccatgacc gatagttcga ttaatcatcg caccctgtcc
     4501 caaactacgg acgataattt cacgataaat ctcttcttcc ggttcgatat agtgaacatt
     4561 tcccgtagcc agaacaggct tgccaaggcg gtctccaacc tctatcaaac tcttgataat
     4621 ggtctggagt tcctccatat ccttgacctg ctctttggca atcaagggtg catagatagc
     4681 cggtggcatg acctcgataa aatcataata cttggccacc tcaaccgccg catccacacc
     4741 ttgagaaacg accacgtcaa aaacttcacc ctctgaacag gctgaaccta aaatcaagcc
     4801 ctctcgatgg gcatctagaa ccgttctcgg aatccgtggc actccttcaa aatacttggt
     4861 attagacaag gaaaccagct taaagatatt ttttagacct acctgattct tgacatagat
     4921 ggtcgcatgc ttgatccgag cttttttgta agaatctgga ctgattagat caatgttgag
     4981 tctagctaaa tcggtcacac catgtttttc tgctacctct ttgataaaga tgaaaagcag
     5041 acgaccagtc gcttccgcat cgtagttggc catgtggtga tgttccaagg ccacaccaaa
     5101 acgcttggtc aaaggcccca aaccatggcg tttatactca ggatagaggt ttctagcaaa
     5161 ctccagcgta tcaataactg gctgactaat ctttggaaga tcatgccgct cataattagc
     5221 attcataaag ccaacgtcaa aggtagcatt gtgggcaact aggaccgtat ccttgcaaaa
     5281 ttcttggaat tcttgcaaaa cttgttctag tggtttggca tttttgacat gatcatctgt
     5341 aattccagtt aactctgtag taaaggctga caagggatgc ccaggattga taaattcatc
     5401 aaattcagca ataacattcc ccttgtacat cttagaagcc gcaacctgaa tcaagtcatt
     5461 atagatagct gaaagtcccg tcgtttccac gtcaaagacc acgtaggttg cttctgacaa
     5521 gtccatctcc acttcgttat agacgatagg gacacggtcc tccacgatat tggcttccat
     5581 cccatagatc agctggattc ccgctttctt agccgcctta tagccatgtg gaaaggactg
     5641 gacattccca tggtccgtga tagcaaccgc cttgtgtccc cacttagcag ctgttgcaac
     5701 aatctcttcg acctctggca aagcatccat agtcgacatg ttagtatgag catgaaactc
     5761 aacccgacgc tcaccttctg gcatcaaatc cttccgctca tagtgaacaa cttcctgcag
     5821 atcctgtacg ttcatagtca aatcgcgtgt gaagttattc atctccacat tccctcgaac
     5881 tcggagccaa gaattcttct tgatgaggtc aaacttctgg gcctcttcct cgtttttaac
     5941 ccacttttgc atagaaaaac ttgaagtata gtccgtcatt ttaaagttga ttaaaacacg
     6001 acctgttcta gtcacttttt gctccacatc aaaaacaacc ccttcaaata ccagacgatt
     6061 ttcctctgtc gtcacttcga tcataggagt aatctccgcc ttatccagct tgggtttagc
     6121 tgcagctttt ttcgcttgaa aatcaaaggc tggtttctct tccgctggag gaggtgccat
     6181 ctgctccagt tgttccatag cacggagcgc ttcctcattg gcagcttgaa caatctgctc
     6241 attttcagca tgaaaggcct cttcctgctc ttgggtcagg acatcattct tctcgacttg
     6301 acagttaaaa gttggaaaac caaacttttc aagttgtttg gctaaattag gaagatgatt
     6361 cttcttaaaa tgttccttat caatcgcttc agatccttca ataaatagct gattaccctc
     6421 agcacgaact tgcaaatttt gataaaggga cttaaaacct tgactagcac atggaccttc
     6481 agagaaagcc tccctatagt aggactgcaa gagctgattt gaaaattctt gagaccgagc
     6541 cttaatttca aaaacagctt tattgcctgt cttagaaaat tcttcgctca aacctttctt
     6601 taattctaaa aagatttcaa tcggtaaaat attagaaaat acgaaatgaa actcccatac
     6661 cttactaatt ttatgaacca caactcgctc aatattggcc tgtgctaaag caggagcctg
     6721 tctcatttca gcaggcatcc ccaattgatt catcaaaatt tcaaaactat ttgacattca
     6781 ttttcctcac attattcttc tactatttta ccatatttag aggtattttc taaagacaaa
     6841 aggaagccac taagtgactt ccttctagag tgaggacgga ttagtcttca cctttatttt
     6901 tcttaataat ttcttcttgt actgacttag gtacatcttc gtagtggtca aataccatca
     6961 tgaatgtacc acgtccttga gatgcagaac gaagaactgt tgcgtaaccg aacatttcag
     7021 caagtggaac gtaagcacga acgatttggc tgttaccgtg tgcttccata ccatctacac
     7081 gtccacgacg agcagttacg tgacccataa catcaccaag gttttcttct ggaacagtga
     7141 ttgttacaag catcattggt tcaaggatag ctggttgtgc tgatttagca gcttctttaa
     7201 gggaaagtga agccgcaatc ttgaaggcag tttcagatga gtcgacatcg tgatatgaac
     7261 catcataaag cttagcttta acgtcaacca ttgggtaacc tgcaagaaca ccgttagcca
     7321 tagattctac caaacctttt tcaaccgctg ggataaattc acgaggaacc acaccaccga
     7381 cgattgcgtt ttcgaattcg aatcctttac cttcttcgtt tggagtaaat tcaatccata
     7441 catcaccgaa ttgaccttta ccaccagact gacgtttgaa gaatccacgt gcttgagtag
     7501 aagcgcggaa tgtttcacgg taagatactt gaggagcacc tacgttcgct tcaactttga
     7561 actcacgacg catacgatca acaaggacgt caaggtgaag ttcacccata cctgagataa
     7621 ctgtttcacc agtttcaacg tttgtttcaa cgcggaatgt tggatcttct tcagccaatt
     7681 tttgaagggc gatacccatc ttgtcttggt cagctttaga ttttggctca accatcaatt
     7741 ggataactgg ttctggaacg ttgattgact caaggatgat tttagctttt tcatctgtca
     7801 atgagtcacc agttgtagta tctttcaaac caacggcagc agcgatatca cctgagtaaa
     7861 cagtgtcgat ttcttgacgg ctgttagcgt gcatttgaag gatacgtccg atacgttcac
     7921 gtttaccttt agaagtattc aatacgtatg aacctgattg aagaacacct gagtaaacac
     7981 ggaagaatgt caaacgacct acgaatgggt cagtcatgat cttgaaggca agagctgcaa
     8041 atggctcttc gtcagatgct ggacgaattt cttcagcgtc tgtatctggg ttaatacctt
     8101 tgattgctgg gatgtcaagt gggcttggaa ggtagtcgat aaccgcatca agcatcaatt
     8161 gaacaccttt gtttttgaag gctgaaccac acaatactgg gaagaattca acgttgatag
     8221 tcgctttacg gataccagct ttcaattctt cgttagtgat ttcttcacct tcgaggtatt
     8281 tcatcatcaa ttcttcgtca gtttcagcaa ctgcttcaat caatttttca cggtattctt
     8341 gagcttggtc aaggtattca gctgggatgt cttcttcaag gatatccgta ccaaggtcgt
     8401 tagtatagat ttcagctttc atcttgatca agtcaatgat accacggaag tcatcttcag
     8461 aaccgattgg caattggatt gggtgtgcat ttgcttgaag acgatcgtga agtgtgctta
     8521 cagagtaaag gaagtcagca ccgattttgt ccattttgtt ggcaaatacg atacgtggaa
     8581 ctccgtactc agttgcttga cgccaaactg tttcagtttg aggctcaaca cctgattgtg
     8641 agtcaagaac ggtaaccgca ccatccaata cacgaagaga acgttgtact tcgattgtga
     8701 agtccacgtg tcctggtgtg tcgatgatgt ttacgcggtg gttgttccat tgagctgtcg
     8761 tcgcagcaga tgtgatcgtg ataccacgtt cttgctcttg ctccatccag tccatttgtg
     8821 acgcaccttc gtgagtttca ccgattttgt ggattttacc agtgtagtaa agaatacgct
     8881 cagtagttgt tgttttaccg gcatcgacgt gagccatgat accgatatta cgagtttttt
     8941 caagtgaaaa ttcgcgtgcc atgaggtttg tttctcctat ttatttttga tttctattct
     9001 attataacac gattttaata aaaacggata ggcaggacct acccgttctc aatgttttca
     9061 tgctattgtt ggtttcaact tacgagatgg taagctgagt tatagctaat actaatcgat
     9121 ttagctaatt tgaacccggg ctaaagttag ttagccgatg tgagctggaa cgggatgctg
     9181 cgtgaaaaag ataaaactcc ttgtattcgt cgaatactgc gtcagtttcc tatttttacc
     9241 ttgcatcctt accgttccta gcatcatgat ttagttgagc tcaagctaaa agtctggaga
     9301 aaaagatgaa tctcattggt tgcaaccgca acctgcttcg attccctatt ttctctggga
     9361 ctttcttaac gctttcgcat cctatcttac caacggaagt gtgcgaatgc acggttagct
     9421 tcagccatac ggtgagtatc ttcacgtttc ttaactgctg caccagtgtt gttagcagca
     9481 tccaagattt cttttgcaag acggtcttgc attgtgtgtt caccacgaag acgagcgatt
     9541 gttaccaacc aacgaagtcc aagtgttgta cgacgttctg gacgaacttc aactgggact
     9601 tggtagttag aaccaccaac acgacgtgca cgtacttcaa gtacaggcat gatgttttcc
     9661 atagctgttt caaatacttc aagtgcatcg ttgccagtag cttctttgat ttgctcaaaa
     9721 gcaccgtaaa cgattgaagc agcagtacca cgtttaccat caagcataac gcggttgata
     9781 agacgagtaa ctagttgtga attgtatagc ggatctggca atacgtcacg ttttggagct
     9841 ctatttttac gactcatttc tctttatccc ctttccttat gcttttggac gtttagtacc
     9901 gtatttagaa cggccttgtt tacgatcgtt aacacctgca gtatcaagtg caccacggac
     9961 gatatggtaa cgtacccctg gaaggtcttt tacacgtcca ccgcgaagaa gcaccacgct
    10021 gtgctcttgc aagttgtgtc cgatacctgg gatgtaggca gtaacttcga taaggttgct
    10081 caaacgtaca cgagcgaatt tacgaagggc tgagttaggt tttttaggtg tcattgttcc
    10141 aacacgagtt gcaacaccac gtttttgtgg tgaagaaacg tttgtttgaa cttttttatg
    10201 actattgtaa ccaacgttca aagctggtga tttagatttt tctacttttg atttacgcgg
    10261 tttgcgaacc aattggttaa ttgtaggcat ctacattctc ctgtgttttt ttatttttgg
    10321 tgatgataca cttggtgaca gatatcatct gtgtgtactt ttgcaacatt tgtcagcacg
    10381 tccctgtaca ctcttgagag accaaaagta aaaagtaccg tctattattg taacaaaatt
    10441 ttcccttgct tgtcaagata tttttctttt ttattggtaa tgttagagat caatttctga
    10501 ataaaaatag ctgagaacac atcatcttcc taataacacg gcttggctta cgtgacattt
    10561 ttatctccgt catttatact gatatataaa atagtacgga aaacttctca aaagtaagaa
    10621 tttctttcac aaatcaaaga aaacgcttgc atattgtttt actacatgct atactgatat
    10681 agaaatttat tgattggaga atcattatga gaaaaacacc atctcacact gagaaaaaaa
    10741 tggtctacag catccgttcc ctcaaaaatg gaactggttc tgtccttatc ggcgcaagcc
    10801 ttgtcttgct tgccatggct acaccaacta tctcatccga cgaaagtaca ccaaccacta
    10861 acgaacccaa caacagaaat acaaccaccc ttgcccaacc tcttactgat acagcagctg
    10921 gctctggtaa gaacgaaagt gatatttctt cacctggaaa tgcaaacgct tccctagaga
    10981 aaacagaaga aaaacctgct gcaagcccag ccgatccagc accacaaact ggacaagatc
    11041 gttcaagtga gccaactact tctactagtc cagtaacaac tgaaactaag gcagaagagc
    11101 ccatcgaaga taactacttc cgtatccatg tcaaaaaact tcctgaagaa aacaaggatg
    11161 ctcaaggact atggacttgg gacgatgttg aaaaaccatc tgaaaactgg ccaaacggag
    11221 ctttgtcctt caaggatgcc aagaaagatg actacggcta ttacctagat gtcaaattaa
    11281 agggagaaca agccaagaaa attagcttcc tcatcaacaa tacagctgga aaaaatctaa
    11341 ccggcgataa atctgtagaa aaactagttc caaaaatgaa cgaagcttgg ttagaccaag
    11401 attacaaggt tttctcttac gagccacagc ctgcaggaac tgttcgcgtc aactactacc
    11461 gcacagatgg caactatgac aagaaatctc tctggtactg gggagatgtg aaaaatccaa
    11521 gtagcgctca atggcctgac ggaacagact ttacggctac aggcaaatat ggccgctata
    11581 tcgacattcc tcttaatgaa gccgcaagag aatttggatt tttattacta gatgagagca
    11641 aacaaggaga cgacgtgaaa atccgtaaag aaaattataa gttcacagat ttgaaaaatc
    11701 atagccaaat tttcctaaaa gacgatgatg aatcgattta cacaaatcca tactatgtcc
    11761 atgatatccg tatgacagga gcccaacacg taggcacttc tagcattgaa agtagctttt
    11821 caacacttgt cggtgctaaa aaagaagata tcctcaaaca ctccaacatc actaatcacc
    11881 taggaaacaa ggtaactatt accgatgttg caatcgatga agctggtaag aaagtgacct
    11941 acagcggaga tttctctgac acaaaacatc cttatactgt tagctacaat tccgaccaat
    12001 tcactaccaa aacaagctgg cgcctgaaag atgagacata cagctatgat ggcaaactgg
    12061 gagctgacct aaaagaagaa ggaaaacaag ttgatttgac cctttggtca ccaagtgctg
    12121 ataaggtttc tgttgttgtc tacgacaaga atgaccctga caaagtagtt ggaactgtcg
    12181 ctcttgaaaa aggggaaaga ggaacttgga aacaaactct agacagcaca aacaaactcg
    12241 gaatcacaga tttcactggc tactattatc aataccaaat cgagcgtcaa ggtaaaactg
    12301 ttcttgcact cgatccttac gctaaatctc ttgctgcttg gaatagcgac gattccaaga
    12361 ttgacgatgc ccataaagtg gctaaagccg cctttgtaga tccagctaaa ctcggacctc
    12421 aagacttgac ttatggtaag attcacaatt tcaagactcg tgaagacgcc gttatctacg
    12481 aagctcatgt gcgtgatttc acttcagatc ctgccattgc aaaagacttg accaaaccat
    12541 ttgggacttt tgaagccttc attgaaaaac tagactatct caaagacttg ggtgtaaccc
    12601 atatccagct ccttccagtc ttgtcttact actttgtcaa tgaattgaaa aaccatgaac
    12661 gcttgtctga ctacgcttca agcaacagca actacaactg gggatatgac cctcaaaact
    12721 acttctcctt gactggtatg tactcaagcg atcctaagaa tccagaaaaa cgaatcgcag
    12781 aatttaaaaa cctcatcaac gaaatccaca aacgtggtat gggagctatc ctagatgtcg
    12841 tttataacca cacagccaaa gtcgatctct ttgaagattt ggaaccaaac tactaccact
    12901 ttatggatgc cgatggcaca cctcgaacta gctttggtgg tggacgcttg gggacaaccc
    12961 accatatgac caaacggctc ctaattgact ctatcaaata cctagttgat acctacaaag
    13021 tggatggctt ccgtttcgat atgatgggag accatgacgc cgcttctatc gaagaagctt
    13081 acaaggctgc acgcgccctc aatccaaacc tcatcatgct tggtgaaggt tggagaacct
    13141 atgccggtga tgaaaacatg cctactaaag ctgctgacca agattggatg aaacataccg
    13201 atactgtcgc tgtcttttca gatgacatcc gtaacaacct caaatctggt tatccaaacg
    13261 aaggtcaacc tgcctttatc acaggtggca agcgtgatgt caacaccatc tttaaaaatc
    13321 tcattgctca accaactaac tttgaagctg acagccctgg agatgtcatc caatacatcg
    13381 cagcccatga taacttgacc ctctttgaca tcattgccca gtctatcaaa aaagacccaa
    13441 gcaaggctga gaactatgct gaaatccacc gtcgtttacg acttggaaat ctcatggtct
    13501 tgacagctca aggaactcca tttatccact ccggtcagga atatggacgt actaaacaat
    13561 tccgtgaccc agcctacaag actccagtag cagaggataa ggttccaaac aaatctcact
    13621 tgttgcgtga taaggacggc aacccatttg actatcctta cttcatccat gactcttacg
    13681 attctagtga tgcagtcaac aagtttgact ggactaaggc tacagatggt aaagcttatc
    13741 ctgaaaatgt caagagccgt gactatatga aaggtttgat tgcccttcgt caatctacag
    13801 atgccttccg acttaagagt cttcaagata tcaaagaccg tgtccacctc atcactgtcc
    13861 caggccaaaa tggtgtggaa aaagaggatg tagtgattgg ctatcaaatc actgctccaa
    13921 acggcgatat ctacgcagtc tttgtcaatg cggatgaaaa agctcgcgaa tttaatttgg
    13981 gaactgcctt tgcacatcta agaaatgcgg aagttttggc agatgaaaac caagcaggat
    14041 cagtcggaat tgccaacccg aaaggacttg aatggactga aaaaggcttg aaattgaatg
    14101 cccttacagc tactgttctt cgagtctctc aaaatggaac tagccatgag tcaactgcag
    14161 aagagaaacc agactcaacc ccttccaagc ctgaacatca aaatgaagct tctcaccctg
    14221 aacatcaaga tccagctcca gaagctagac ctgattctac taaaccagat accaaagtag
    14281 ctgatgcgga aaataaacct agccaagcta cagctgattc acaagctgaa caaccagcac
    14341 aagaagcaca agcatcatct gtaaaagaag cggttcgaaa cgaatcggta gaaaactcta
    14401 gcaagaaaaa tatacctgca accccagata gacaagctga acttccaaat acaggaatta
    14461 aaaacgaaaa caaactccta tttgcaggaa tcagcctcct tgcgctcctt ggtctcggtt
    14521 tcttactaaa aaataaaaaa gagaactaaa ctagccctcc tatagaaaaa tcccccaagc
    14581 attatagctc gggggattaa ttttcgtaca atatttgttg tcctaataaa cttgattagg
    14641 attttttatt aagcctcttt catagcaaaa taagctcgta ctttgggtgc aacttgtgtt
    14701 ccgaagagtt caatagctct cagaacctgg tcatgaggca tagaaccaag cggtagatga
    14761 agcatgaagc ggtccaatcc taaatcctct atcatgcgaa tcaatttttc ggccacctga
    14821 tctggattgc caacaaacat ggcgccattt gaccctacct gctccaaata ttgctcataa
    14881 cgcaattcct gccagtgcgg acggtctttg gaaatagcat ccaccacttg cttagtcgga
    14941 tggaaataat ctttcaccgc ctgctcacca tcttccgcaa tccaccccca agaatgggct
    15001 cccactttca agtctttgtc agcatggacc gcttcgcttc caatctcacg ataagcctga
    15061 atcaactttt taaaataacg tggattacca ccaataatag catatacaat cggtagacca
    15121 gcctgagcaa tcttcactgt tgattcgaca tgaccacctg tagctatcca caagggcaat
    15181 ttgtcctgaa ctggacgagg ataaacttct ttaccagcaa tcgtttgagt caatcgacct
    15241 tgccagtcta acttggtctt ttcattgact aactgaagca agtctaattt ctcatcaaaa
    15301 agagagtcgt agtctttcaa gtcataacca aacagaggga aagattccgt gaaagagccc
    15361 cttccagcca taatctccgc tcgtccattt gacaaagcat cgatagtggc atactgttgg
    15421 aacaaacgaa tcggatccat gcttgacaga atgctgactg cactggtcaa acggattttc
    15481 ttggtattga ctgccccagc ggccaggaca atctctgggg ctgatactgc aaaatccgcc
    15541 cgatggtgct cgccaatccc atatacgtcc aaaccaacct tgtcagccag ctcaatctct
    15601 gccaccaact ggcgaatgcg ttcagcatga ctgtaagttt gtccagtccc ttcaagctcc
    15661 gttatttccc caaatgttga aattcccaat tctaccattg tgattctcct tgtctatctc
    15721 tgtccttcaa tttgaaaaat tattctaaca ctcaatgaaa atcaaagagc aaactaggaa
    15781 gctagccgca ggttgctcaa aacagtgttt tgaggttgtg gatagaactg acgaaatcag
    15841 taaccatacc tacggcaagg cgacgttgac gtggtttgaa gagattttct aagagtataa
    15901 cacgaatctt gagtacaagc aaccaatttg ctcacaagaa aaagcctaga taactagact
    15961 tttttagctt attctaccgt tactgacttg gcaaggttac gtggtttgtc cacatcgagg
    16021 ccacggtgga gggttgcaaa gtaagcgact aattgcgttg gtacgaccat tgaaattggt
    16081 gagaggtatg gatgtacggt cgtaaggacg atatcgtcgg tatctttggc tacattctct
    16141 tctgcgatag tgaggacttt ggcaccacgg gctgcgacct cttggatatt tccacgagta
    16201 tggttggcaa gaactggatc tgacaagaga gccaaaacag gcgttccttc ttcaatcaag
    16261 gcaatggttc cgtgcttgag ttctcctgcc gcaaaacctt cacactggat ataagaaatc
    16321 tctttgagtt tgagacttgc ttccatggct acgtaataat cttgaccacg tccgatgtaa
    16381 aaggcgttac gagttgtttc aagaagttca cgaaccttgg cttcaatggt ttctttctct
    16441 gaaagagttg attcaataga ctgagctacg attgacaatt catgaaccag gtcaaaggct
    16501 tgcgctttag cattaccatt tgcttctccg actgcttttg caaggaaggc aagggctgcg
    16561 atttgcgctg tataggcttt agttgatgcc acggcaattt caggacctgc gtgaaggagc
    16621 atggtatagt tggcttcacg tgagagggtt gaacctggaa catttgtcac tgttaagctt
    16681 ggaattccca tttcattagc cttgaccaaa acttgacgac tatccgctgt ttcaccagat
    16741 tggctgataa agatgaagag tggtttcttg ctgagaagtg gcataccgta gccccactca
    16801 gatgagattc caagttcaac tggtgtatct gtcaattctt ccaacatctt cttagaagca
    16861 aatcctgcat ggtaagatgt tccagctgca aggatgtaga tgcggtctgc gtcttgaaca
    16921 gccttaatga tatctgggtc tacgacaact tgaccagcct catctgtgta ggcttggatg
    16981 agtttccgca taacagttgg ttgctcgtca atttccttga gcatgtagta agggtaagtt
    17041 cccttaccga tatctgacaa gtcaagttca gcagtgtagc tagcacgctc acgacgattt
    17101 ccatcatagt cttgaacttc cacgctatca gccttgacga ttaccaactc ttggtcatga
    17161 atttccatgt attggttggt ttcacgaatc atagccatag catctgagca gaccatattg
    17221 tagccttccc caagaccaat caaaagtgga gatttgtttt tcgctacata gatgacatct
    17281 ggattttcag agtcaatcaa ggcaaaggca tatgaaccac ggataatatg aagagctttt
    17341 ttaaaggctt caagaactga gagaccgtct tcttccgcaa attttccaat caaatgtacg
    17401 gcgatttccg tatctgtttg ccctttgaag tggtgcccag caaggtattc ttctttaatt
    17461 tcaaggtagt tttcaatcac cccattgtga accaagacaa aacgttctgt ctcagagcgg
    17521 tgtgggtgag cattgtcttc cgttggtttc ccatgagttg cccaacgagt atgtccgata
    17581 ccagttgttc cctcaacacc agctgtcttg gcagacaatt ctgcgatacg accaacagcc
    17641 ttcaccaaat ggttatcagc accatctagg acaaaaattc ccgcagaatc atagccacgg
    17701 tattcaagct tttcaagccc ttgaatcaaa atatcagttg catttgtgtt tccaacaaca
    17761 ccaacaattc cacacatagt atatacgaca caggcaagct gtgctttctc cttaaaattg
    17821 gtatagtcta attcatcttt tatagaatca gcaaaaacag tatatacttg tttctttcac
    17881 ttgtcaagag taaaaattgg tatagttcaa attaagctcc tgtaagcaaa aaactctgac
    17941 cgattgggat aatcagtcag agtccttttt aaaatccatt attatcgctt aattttttga
    18001 accagtggcc tgatttcttc agacgacgtt cttgcgtttc caagtctaat tcgaccaaac
    18061 catagcgatt tttatagctg ttgagccatg accagcagtc aataaaggtc caaatcaagt
    18121 agcccttaca gttggcacca tcttcaatgg cacggtgaag ttcacgaaga tgacctttta
    18181 caaagtcaat acggtaatca tcttgaatca ttccatcttg acggaatttt tcttcccctt
    18241 caacacccat accattctca gtcaacatcc attcaatatt gccataattt tccttgatat
    18301 tttgggcgat gtcataaatc ccttgctcat aaatctccca accacggtga gaattgattt
    18361 tacgtccagg catcacataa ggctcgtaaa aatgttctgg taagagtgga ctctctggat
    18421 gcttagcaaa tcgaggagcc ataacacgca aaggttgata gtagttcaca ccaaggaagt
    18481 ccaccgtatt atcatgaatg agttccaact cttcctctgt agcatcaggt aaaagaccgt
    18541 gttcatgcaa gatttctacc aactcctgtg gataagtccc caagacagat ggatctaaga
    18601 aagattgggc ctgaaaaagg gccgcaatac gagctgcctt gacatcagca ggatgctggc
    18661 tacgtggata agccggtgtc aagttgagga caatcccaat cttggaatca ggcaaaagtt
    18721 catggcaagc cttaacagcc cggctgctgg ccaattgtgt atgataggct accttaacag
    18781 ctgcctctgc atccacctta tgtggataat gggcatcata aaaataacca aattctacag
    18841 gaacgatggg ctcgttaaag gtaatccatt gatccactaa atctccataa gtctcaaaac
    18901 aaaaacgagc atagtcttca taggctgaga ctgtcgcctt attttcccaa ccatcaccat
    18961 cctcttgaag ggcaaaaggt aaatcaaaat gatagagatt gactaacaga cgaattcctt
    19021 tagccttaat agcctcaaag accttacgat aaaaatccac accttgaggg ttgacttttc
    19081 cacagccttg tggaaaaatc cgtgaccact gaatagaagt ccgaaagact gtgtgaccag
    19141 tctctaacaa aagctcaata tcccgctccc aattttcata aaaagtcgat gtcttatctg
    19201 aaccaatccc attatagtaa cgatttggct ccacttggaa ccagtaatcc cagagattgt
    19261 ctcccttacc gtcaccagct acacgtcctt ctgtctgcgg tccagaagta gaggatcccc
    19321 agacaaaatc ctttggaaat cttagcataa catttacctc tttatctact catttctccc
    19381 attatacaga aaaaacaagg taaaaactag ttacattttt tccttgtttt tcttctgatt
    19441 atagttttta tttcttgctt aggatttcaa gcgtttcaag cacgttatct gcatgaacct
    19501 caatggtgtc accagttgcc ttgatcttaa cttctacaat gccatcggcc gcttttttac
    19561 caacagtgat acggattgga agaccaatca agtcactatc gctaaattta acaccgacac
    19621 gttcgttacg gtcatctgtc aagacttcat aaccagctcc catcaagctt gcttcaagtt
    19681 tttctgtcaa ggcttgcgct tcttcatcct tgacattgac agtaatcaaa tgcacatcaa
    19741 atggtgccaa ttctttaggg aaattgattc cccaagcgta acggtattca ccttttggcg
    19801 ttttgttaac aaagaggcga gcgtgttgct ccatcactgc tgaaagaaga cggctgacac
    19861 cgataccgta acatcccatg atgattggca cagcacgacc attttcatcc aagacatctg
    19921 ctcccatgct tgctgagtag cgagttccga gtttgaaaat atgaccgatc tcaataccac
    19981 gcgcaaagtt aaggacacct tgtccatctg gggaaatttc accctcacga acttcacgga
    20041 tatccacata ttctgcagta aaatcacggc ctgggttcac accagtcaag tggtagccat
    20101 cttcgttagc accgacaact gcattgcgaa catcttgcac cttacgatct gcaataattt
    20161 taatattctc tggcaaacca actggtccaa gtgaaccaaa tcctgcttga acaacattcg
    20221 ccacttcttc ttcgctagca acgtcaaaga aatctgctcc taagtggttt ttcaacttga
    20281 cttcgttgag ttggtcattt ccaactagaa gggctgcaac aagctcacca tctgcaatgt
    20341 agaagagggt tttaatcgtt tgttcttctg gaacattgag gaaagctgca acttcatcaa
    20401 ttgatttaac atctggcgtt gcaacacgag taacttcttc ttcagcgaca acacggttgc
    20461 ttggtttgta ctcgtttgtt gccatttcta agttagctgc atagctagac tcacttgagt
    20521 aagcaatggt atcttcacca gagactatcc atttgagcaa ttctgccttg atttcttctt
    20581 gcacttctgc aggaatttcg tcaaatgagg caactgactt gtccaagaca acccagcggt
    20641 caaggtctgt acgagcagat gtaatggcca taaattcttg gctatcctta ccacccatgg
    20701 ctccaccgtc accaataata gccttgaagt ctaaaccact acgagtgaaa atacgctcat
    20761 aggctgcttt gtactcatca taaacactat ccaaactatc atagttagcg tggaaactat
    20821 aagcatcctt catgataaac tcacgtgtac gaagaagtcc attacgtggg cgtttttcat
    20881 cacgatactt gggctgaatt tgataaaggt tgagtggcaa ttgcttgtaa gatttaacag
    20941 aatcacggac aatagctgta aaggtttctt cgtgagttgg acctaagata aagtctgatt
    21001 tttcacggtt ttttagtttg taaaggtctt caccataggt ttcgtaacga cctgattcac
    21061 gccacaattc tgcactaaga agggctggag ccaacatctc aacagcacca atcttttcga
    21121 attcttggcg catgatgttt ttagcttttt caatcacacg attggcaagt ggtagataag
    21181 aataaacacc tgctgaaact tggcgaacat aaccagcacg caacataaga gcatggctga
    21241 taacttgagc atcgcttggc atttcgcgaa gcgttgggat aggcatttta ctttgtttca
    21301 taatattcct cgattatcta aaaaagagtc gcataatgtc attccaagtc acagcaatca
    21361 tcaagacaac catgatgacc actccggcca aggtgacata ggtttcaatt tcttgtttca
    21421 atggtttgcg gcggatggct tctaggatat tgagcacaat cttaccacca tccaaggctg
    21481 gaatcggaat aagattaaaa atcccaatat tgatggaaat cattgccaag aagtacaaga
    21541 tattttcaat tccattttta gcagcatcac tacttgcctt aaagatagca acaggtccac
    21601 ccaacttgtt caaatccggt tggaaaatca gatttttcag agctgagaga attcggagag
    21661 ctgagtcagc agcagttgta aaaccaccta caaacatgga tagaaaatct gacttaaccc
    21721 ccggttgaac acctagaagg taacgacctt gactatcttc gggtgtaaca gtgacttgtt
    21781 tgtcactccc cttttcagaa atagtcacat ccaaagtcgg tgccgtctta tctttggttt
    21841 ctgtttccac agcttggatc aagctttccc agttgctaac ctcatgtgag ccaatcttgg
    21901 taatttgtgc cgtttctggt actcctacct tggccaaggc accttggggc atgatatgga
    21961 actgattggt atcaacatct ctgacaccac cctgcataaa gattaaaacc caaaaaacaa
    22021 cgacacctaa gataaaattg ttcataggac ctgcaaaatt ggtaatcagt ttgccccaga
    22081 tagtcgcatt ttgatattga acatctaaag gtgcaatccg aacctcagta ccatctgctt
    22141 ccacaaccgt tgcatcgtga tccactgcaa atgttttttc ttcttccaga accaatcctt
    22201 tgataaagag cttgtcttca aaatcaaact gggtcacctg catagggagg gctgtttgat
    22261 ccaatttttt acctgagaga ttgatgcgtt taaccttacc atcatcagca agtgtcaaac
    22321 taacaggcgt tcctgtcttg atttcagttg tatcatcacc ccaaccggcc atgcggacat
    22381 agccacccag aggcaagatt cgaatggtat aggccgttcc atccttgcca atgtgagcaa
    22441 aaattttagg tcccataccg atggcaaatt cacgtactaa aatccctgat ttcttggcaa
    22501 agtagaagtg cccgaactcg tgcaccacta caataatccc gaaaaccaga ataaaggtta
    22561 aaattccgag catagcgttt cctccgtctt ttgattaaaa gagtccaaat aagtgcatga
    22621 ttggaaatac aagcaacata ctatcgaaac gatccaaaac accaccatgt ccagggataa
    22681 atttcccaga atccttaaca ccaaaatgac gtttgatcga actttctagt aaatcaccaa
    22741 attgtccagc aatgctaaag aaaatagcaa agactgacat cttgtaaatt ccatatggaa
    22801 gagcaactgt actgtcaact atcataaaga taatggttac taaaattgct cctaaaatac
    22861 cacccaaggc accctcaagg gttttattag gcgataccct tggtgctaac tttcgtttcc
    22921 catagttcat cccaacaaga taggcaccac tgtctgtcgc ccagacgata cacaaggcta
    22981 agagagcctt gtccaaacct gcaacacgag catctagtaa agcattaaat ccaaagccca
    23041 cgtagaagct catagcaaga gggaaaaccg catcctcaat cgtataagac ttgctaaaaa
    23101 cggtcgttcc taacatgatt gaaatcaaaa cactataggc aaccacattc ccatcaactg
    23161 gcaaaaaagt caggtaattc tccaagggaa tggtcaatgc aaaggttgca aagagggtca
    23221 agaggccctc catcgtcatg gtctctagac ctctcatctt caaaagttca tgcatggcta
    23281 gcatggctat gattccgatt gctatctgaa gcaagaggcc cccaatcatt aaaattggta
    23341 ggaaaatagc cagggcaatc cctgcaaaca aggttctttt ctgtaaatcc tgggtcatat
    23401 ttcctcctaa actcctccaa atcggcgatg acgacgatta taggcaagaa tagcttcctg
    23461 caaggccgct tcgtcaaaat caggccataa ggtgtccgta aaataaagct cactataggc
    23521 tccctgccat ggaagaaaat tgctcaaacg taattctcca ctagtacgga taatcaagtc
    23581 tgggtctcgt aagtccttag gcaaatgctg agtaaagaga tagttaccaa tcaattcctc
    23641 tgtgatgtca cctgggttga ttttggcatc taaaacatcc tgggaaatca acttaagcgc
    23701 ctgtgtaatc tcagcacgtc caccatagtt aagagcaaaa ttaagaatca atcctgtgtt
    23761 gttcttagtc aattcctcag ccttggttaa agcttcaaag gtttgcttag gcaggcggtc
    23821 tgtctcccca atcatttgaa tcttaacatt attcgcatgt agttccggga cataattatc
    23881 ataaaactct actggcaagt tcatgataaa cttgacttcc tgatctggac gggtccagtt
    23941 ttccgtagaa aaagcataga ccgtaataac cttgacgccc agtttgttgg ctgccttggt
    24001 cacggtttgc aatgcttcca tgcccgcctt atgtccaaaa actcgcggtt gcatacgttt
    24061 tttagcccaa cggccattgc catccatgat gatgccgata tgagcaggaa cctgtgtcgg
    24121 aacctctact tccacagcct tatctttctt aaaaaatcca aacatgatct tattcctatt
    24181 caaaaatcta tcgtttcatt ataccatatt tccccatttt cttctatcac taagctattt
    24241 attctcaggc accatgccca tttttcaaaa aaataagccg cctgattggg cgactttatt
    24301 tttataggga gattattatg aaaaagtttt aggagtttaa gttaaggtct tcttaactta
    24361 tgaacttagt gtacactccc tagcttaaag tttccttaag tatttttaaa aatcaaattt
    24421 ttccatttct cctgccaatt tttcttggat aaacgtgttt gatagagttc cattcggtct
    24481 tcattttcta agaaatgagg agttggacga acttgaaaat tcaaaatatc ctccaaacca
    24541 taaggtgcat agagttcaaa atctgattct tcattcaagc gcagtccaac tgccgtacac
    24601 cgttctggat acttactcat agcatcacga gaactggtat aggaagcagt gtgaggactg
    24661 tgctgatgca tatagacctg atttttcaat tcccactggt actgaggaaa atcctctctc
    24721 agctttttct ccagtaataa ggtttcctca taagaaaaat ctggatcaaa gaaaatcaca
    24781 tctatatctg tttcatgatc aaaaggggat ttgtctgaca aaagattcca gatgaaattt
    24841 ctgacagaac ctgctgccaa ctacgagtct ttcaaaccaa ggtctcggat gatcgtcaga
    24901 atggccatca tatctggatt ttctctaaaa gcctctaaga tttcttgctt atttttcact
    24961 gtattcataa cctaagtgct catatgcctt agcagtcgcc acccgtccag accgtgtccg
    25021 catgataaaa cctttttgaa tcaagtaagg ctcatacatg tcttcaactg tctcacgctc
    25081 ttcggcgata ttgacagaaa gagttcctag accaacaggt cctccactgt acatctcaat
    25141 catggtacga aggatttttt gatccacata gtccaaacct tcatggtcaa catccagcat
    25201 agtcaaagcc ttatcggtaa taatatcatc gattacccca ttccccatta tctgggcaaa
    25261 atcgcgcacg cgcttgagga gacgattggc aatacgaggg gttccacgac tacgtagggc
    25321 caactcagat gctgcctcat gagtgatttc catctcaaaa atatctgccg tccgctcgac
    25381 aatttctgtc aagtcagcat gggcataata ctccatatga cctgtaatcc caaaacgtgc
    25441 ccgtagtgga tttgagagca taccagcccg agtcgtcgca ccaatcaagg taaaaggagg
    25501 caactccaaa tgaacactgc gactgccttc accagcccca atcataatat cgatgtagaa
    25561 gtcctccatg gcactataaa gcacttcttc cactgacatg ggtaagcgat gaatctcgtc
    25621 aataaagagg acatctccag gctctaactc attcaaaatc gctaccaaat cacccgcttt
    25681 ttcgataaca ggaccagacg tttgcttgag attgactccc agttcattgg caatgacaaa
    25741 agccatggtt gttttcccaa gccctggagg gccaaataag agcacatgat ccagcgcttc
    25801 atcccgcatt ttagcggctt cgataaagat ctgaagctga tccttaacct tatcctgacc
    25861 aatatattca cgtaaatact gaggacggag cgtgcgttct actaactcct catcacccat
    25921 catctcatta tctaaaattc tactcatggc tctattatat caaaaaaaca agccacaaac
    25981 aaaaaagcca cctgattggg tgactcctaa gtttagcact tatgtggtat aatattatac
    26041 ggcacttcta caccgcctac gaaaggaggt gagatagccc atgatggaat tagtactcaa
    26101 aactatcatc ggaccaattg tggtcggtgt cgttcttcgt atagtcgata aatggctaaa
    26161 caaggacaaa tagtgtcaaa aaagacctca agcttatttg gtcgtgagct tggggtcttt
    26221 tctagcctat gatatagaac tagtactcaa ttccttttta ttatcccata gttcacgaat
    26281 tttgtcaaag gtttacattt tcttcaaccg ctgtacgaca agacggttaa gattaagaga
    26341 acgttaggga ttctatcaat ttcatagaaa ttttgatttc gtaaacgaag agacaatctt
    26401 acatgtcact tctcatttaa tacgccacta ctagacaagc aaaatcatta ttacagtagt
    26461 tccagtcctt caattaacag tcacttacaa tcaaattgag tttgaactag ctgaagcgac
    26521 cacagaccta tttcttagtc atattcgcta aaaaagtccc cgccaattcc ccgaccaaaa
    26581 tccgaaaaat accgaaaaat atcgaaaaat tatttttaga atagtcccca aaagcctgaa
    26641 atagagctaa aaaactccac ctgattgggt ggagttaagg gagattatta tgaaaaagaa
    26701 aagtttagga ttttattaaa taaagttagg aggtctttat ttaataacta catgatacaa
    26761 gacgaaactt aaaactagct taacttttct aaaattttac cattttgcaa aaaatttcta
    26821 tcaccagcac ctcaccacgc aaaaaagcca cctgattggg tggcttcatt aggagattgt
    26881 gatgaaaaaa gtttaggatt ttattaaata aagttaggag gtctttattt aatgattata
    26941 taatactaga ccatccttaa attttgctta agaaaaaaca agttttgtta ttttttacga
    27001 ttcatccaag tcatccctat ccaattatag gtggataaaa tttcaaagcc catagaacga
    27061 ttaaattcca cgtttttttc tgtctgttct gtcgccagct ggacttgata ggcctcttta
    27121 aaatttccta aagcctgttt catcaaggag ctaccaatcc cttggcgctg atagctagac
    27181 aaaacaatca aatcctgtac aaaaactgat gaaaaaccat ctccaaccaa acgaatcaag
    27241 cccacaacag catcaccatc aagtgccaga taaattatta atgaatgata caaggtctac
    27301 tccagcatct gatgttgatt tatataattt gtccaaccga cagcctgata gagatgcaaa
    27361 acatcctcga acttgacgat ttcttgcttt ctaatagtga tcatgtcaac acctcttaaa
    27421 actctctcaa gctcttgtac tgctgtccat ttttatcaaa attttcagga cgcaaccatg
    27481 tttccaaacg atctttgact ttgggccagt ccttatcaat catagacaac caatccgtat
    27541 ctctcgtacg ccccttataa accactgcct gacggaaggt tccttcataa ataaagccca
    27601 aacgctccgc agtacgtctg gatggcaggt taagagcatc gcatttccac tcataacgac
    27661 gatagttaag ctcttcaaag acatagcgag ccagtagata ctgggcttct gtccctatcc
    27721 gtgtccccct gagttttgga gaaaaagtaa cagctcccac ttctattact ccgttactgg
    27781 ccaatacgca tgagagaaaa agttcccaaa gccttaccag ttgccttgtc tatgattgca
    27841 tagtaaaaac ggtccttacg agccaacatc tgatttaaaa ggctgaccag ttcctccatg
    27901 tctgctactg gctcctgaaa gaggtaggtc cacatctcct gaggagtatc aggaccataa
    27961 acagctagca aatcctccgc atgcttttcc actgaaagag cctctatcct agcataacgc
    28021 ccttctaaga gatcaataga agtcagttca cctggtgtat aaccttccat tgactcacca
    28081 atcatctgac catattcgtt tactggtata actttctcct tgtttcgctt ttcaaacttt
    28141 atagttgccc atagtatagc g
//
LOCUS       DBEJZJ010000026        26890 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000026 DBEJZJ010000000
VERSION     DBEJZJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.26"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            284..781
                     /locus_tag="ACL3R8_001408"
     CDS             284..781
                     /locus_tag="ACL3R8_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR1314274.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            781..2436
                     /gene="dnaX"
                     /locus_tag="ACL3R8_001409"
     CDS             781..2436
                     /gene="dnaX"
                     /locus_tag="ACL3R8_001409"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR1314275.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2464..2658
                     /locus_tag="ACL3R8_001410"
     CDS             2464..2658
                     /locus_tag="ACL3R8_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR1314276.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2808..3578
                     /gene="sufC"
                     /locus_tag="ACL3R8_001411"
     CDS             2808..3578
                     /gene="sufC"
                     /locus_tag="ACL3R8_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR1314277.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3606..4868
                     /gene="sufD"
                     /locus_tag="ACL3R8_001412"
     CDS             3606..4868
                     /gene="sufD"
                     /locus_tag="ACL3R8_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR1314278.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKDAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4879..6105
                     /locus_tag="ACL3R8_001413"
     CDS             4879..6105
                     /locus_tag="ACL3R8_001413"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR1314279.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6092..6532
                     /gene="sufU"
                     /locus_tag="ACL3R8_001414"
     CDS             6092..6532
                     /gene="sufU"
                     /locus_tag="ACL3R8_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR1314280.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6586..7998
                     /gene="sufB"
                     /locus_tag="ACL3R8_001415"
     CDS             6586..7998
                     /gene="sufB"
                     /locus_tag="ACL3R8_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR1314281.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8229..9470)
                     /gene="pbp3"
                     /locus_tag="ACL3R8_001416"
     CDS             complement(8229..9470)
                     /gene="pbp3"
                     /locus_tag="ACL3R8_001416"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR1314282.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9573..10682
                     /gene="cozE"
                     /locus_tag="ACL3R8_001417"
     CDS             9573..10682
                     /gene="cozE"
                     /locus_tag="ACL3R8_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR1314283.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGVFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11328..11675
                     /gene="ssrA"
                     /locus_tag="ACL3R8_001418"
     tmRNA           11328..11675
                     /gene="ssrA"
                     /locus_tag="ACL3R8_001418"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11845..11932)
                     /locus_tag="ACL3R8_001419"
     tRNA            complement(11845..11932)
                     /locus_tag="ACL3R8_001419"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11896..11898),aa:Ser,seq:gga)
     gene            12094..12834
                     /locus_tag="ACL3R8_001420"
     CDS             12094..12834
                     /locus_tag="ACL3R8_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1314284.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12831..13742
                     /gene="pfkB"
                     /locus_tag="ACL3R8_001421"
     CDS             12831..13742
                     /gene="pfkB"
                     /locus_tag="ACL3R8_001421"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR1314285.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13739..15691
                     /locus_tag="ACL3R8_001422"
     CDS             13739..15691
                     /locus_tag="ACL3R8_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR1314286.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15828..18080
                     /locus_tag="ACL3R8_001423"
     CDS             15828..18080
                     /locus_tag="ACL3R8_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR1314287.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAVFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKEIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18124..18558)
                     /locus_tag="ACL3R8_001424"
     CDS             complement(18124..18558)
                     /locus_tag="ACL3R8_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR1314288.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            18721..20805
                     /locus_tag="ACL3R8_001425"
     CDS             18721..20805
                     /locus_tag="ACL3R8_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314289.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKISALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GGLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            20815..21192
                     /locus_tag="ACL3R8_001426"
     CDS             20815..21192
                     /locus_tag="ACL3R8_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314290.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            21352..22494
                     /locus_tag="ACL3R8_001427"
     CDS             21352..22494
                     /locus_tag="ACL3R8_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR1314291.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEVLEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            22503..23717
                     /gene="thiI"
                     /locus_tag="ACL3R8_001428"
     CDS             22503..23717
                     /gene="thiI"
                     /locus_tag="ACL3R8_001428"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR1314292.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            23852..24665
                     /locus_tag="ACL3R8_001429"
                     /pseudo
     CDS             23852..24665
                     /locus_tag="ACL3R8_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            24687..25426
                     /locus_tag="ACL3R8_001430"
                     /pseudo
     CDS             24687..25426
                     /locus_tag="ACL3R8_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            25439..26605
                     /locus_tag="ACL3R8_001431"
     CDS             25439..26605
                     /locus_tag="ACL3R8_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR1314293.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         7966 a         4941 c         5868 g         8115 t
ORIGIN      
        1 cttgtgtgta tccttattga tgatgtctaa aatctggata ttagggtctt taatgtctag
       61 taattttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttgatcgc
      121 ttttcattat aggtcatatg ggactttttt tctacacaaa aataggctcc ataatatcca
      181 taggggattt acccactaca aatattatag agcccaaaat cctttgttta ctaaacaagg
      241 gatttttctt ttgtctctgc tccttttttg atataatagt tctatgttaa aatcagaaaa
      301 acaatcacgt tatcaaatgt taaatgaaga attgtccttc ctattggaag gcgaaaccaa
      361 tgttttggct aatctttcca acgccagtgc tctcataaaa tcacgttttc ctaataccgt
      421 atttgcaggc ttttatttgt tcgatggaaa ggaattggtt ttaggcccct tccaaggagg
      481 tgtttcctgc atccgtattg cactaggcaa gggtgtttgt ggtgaggcag ctcactttca
      541 ggaaactgtt attgttggag atgtgacgac ctatctcaac tatatttctt gtgatagtct
      601 agctaaaagt gaaattgtgg tgccgatgat gaagaatggt cagttacttg gagttctgga
      661 tctggattct tcagagattg aggattacga tgctatggat cgagattatt tggaacaatt
      721 tgtcgctatt ttgcttgaaa agacagcatg ggactttacg atgtttgagg aaaaatctta
      781 atgtatcaag cactttatcg aaaatataga agtcaaaact tctcccagtt agttggtcaa
      841 gaagttgtgg ctaagactct taaacaagcg gtggagcaag agaaaataag tcacgcttat
      901 cttttttctg gtcctcgtgg aacgggaaaa accagtgttg ctaaaatctt tgccaaggct
      961 atgaactgtc ccaatcaagt gggtggcgaa ccttgcaata actgctatat ttgtcaagca
     1021 gtgacggacg gtagtttaga agatgtcatt gaaatggatg cagcttctaa taatggggta
     1081 gatgaaattc gcgaaattcg tgataaatct acctatgcgc ctagccttgc tcgttataag
     1141 gtttatatca tagatgaggt tcacatgctg tctacagggg cttttaatgc cctcctaaag
     1201 acgctggaag aaccaacaca gaatgtagtc tttattttgg ccactactga attgcacaag
     1261 attcctgcta ctattctatc ccgtgtgcaa cgttttgagt ttaaatcaat taagacacag
     1321 gatattaagg aacatattca ctatatctta gaaaaagaaa atatcagttc tgaaccagag
     1381 gctgtggaaa tcattgccag acgggcggaa ggtggaatgc gggacgcctt gtctattttg
     1441 gatcaagccc tgagtttgac acagggaaat gagctgacga ctgctatctc tgaagaaatt
     1501 actggcacca ttagcctatc agccttggat gattatgtgg cggccttgtc tcaacaggat
     1561 gttcccaaag ctttgtcttg cttgaatctt ctttttgaca atggtaagag catgactcgt
     1621 tttgtgaccg atcttttgca ctatttaaga gacttgttaa ttgttcaaac agggggagaa
     1681 aatactcatc atagttcagt ctttgtagaa aatttggcac ttcctcaaaa aaatctgttt
     1741 gaaatgattc gcttagcaac agtgaattta gcagatatta agtctagttt gcagcccaag
     1801 atttatgctg aaatgatgac cgtccgtttg gcggaaatca agcccgaacc agctctatca
     1861 ggagcggttg aaaatgaaat tgctacgctg agacaggaag ttgcccgtct caaacaagag
     1921 ctttctaatg caggtgcggt tcctaaacaa gttgcaccag ctcctagtcg accagctacg
     1981 ggcaaaacag tctatcgtgt cgatcgcaat aaagtgcaat ctatcttaca agaggccgtc
     2041 gaaaatcctg atttagcacg tcaaaatcta attcgtttgc agaatgcctg gggagaggta
     2101 attgaaagtc taggtgggcc ggacaaggct ctgctagttg gttctcaacc ggttgctgcc
     2161 aatgaacacc atgctattct tgcttttgag tctaacttca atgctggtca aactatgaaa
     2221 cgagacaatc tcaataccat gtttggtaat atcctcagtc aggcggcagg tttttcacct
     2281 gagattttag ctatttccat ggaggaatgg aaagaagttc gcgcagcctt ttcagccaaa
     2341 gccaaatctt ctcaaactga aaaagaagta gaagaaagcc tgattccaga aggatttgaa
     2401 tttttggctg ataaagtgaa ggtagaggaa gactaaagaa agatttcatg atacaataag
     2461 tttatgaata aacaacaatt tattattatg gcgctattta cagctgctga gacctatttt
     2521 ttcaatgaag cctggatgac tggccgctat attatggcag ccttttgggc aattttactc
     2581 tttagaaatt tccgagtcag ttatgtgatg ggtaaaattg ttgatgtcat cgatcagcat
     2641 tttaatagga aagactagcc ctcagcttcc agacaaaatc aaagcctttt aggctttttt
     2701 ttgttatact agaaaagtat atttatagaa tttttgctct atttctgggg aaatcagacg
     2761 tttttctagt aagtactgta aaagttttga aaaagaaagg aactatcatg tcagtaatag
     2821 agatcaaaga tcttcacgtt gagattgaag gaaaagaaat tttaaaaggg gttaacctga
     2881 ccctgaaaac aggagaaatt gccgctatca tgggaccaaa tggtacaggt aaatcgactc
     2941 tttctgccgc tatcatggga aatccaaact atgaagtaac taaaggtgaa gttttgtttg
     3001 atggcgtaaa catccttgag ttggaagtgg atgagcgtgc gcgtatggga cttttccttg
     3061 ctatgcaata cccatcagaa atccctggaa ttaccaatgc tgagtttctt cgtgccgcta
     3121 tgaatgcggg taaagaagat gatgagaaga tttcagttcg tgagtttatt actaagctag
     3181 atgaaaaaat ggaattgctc aacatgaaag aagaaatggc agagcgttac ctcaacgaag
     3241 gcttctctgg tggtgagaaa aaacgcaatg aaattcttca acttttgatg ttggagccaa
     3301 catttgctct tttggacgag attgactcag gtcttgatat tgacgctctt aaagttgtgt
     3361 ctaaaggtgt caatgccatg cgtggtgaag gttttggtgc tatgatcatc actcactacc
     3421 aacgtctttt gaactatatc acacctgatg tggtacacgt gatgatggaa ggtcgtgttg
     3481 tcctttctgg tggtccagaa ttggctgcgc gtttggaacg tgaaggatac gcaaaactag
     3541 ctgaagaact tggctacgac tacaaggaag aattgtaatt ccctcgtatc ttttaggaga
     3601 agtaaatgac tagagaaaat attaaacttt tttcagaaat gcacgctgaa ccaagctggt
     3661 tggctgatct ccgtcaaaaa gcttttgaca agattgagac tttggaatta ccagttattg
     3721 agcgtgtcaa attccaccgt tggaatctgg gtgatggaac gattacagaa aatgagccat
     3781 cagcaaatgt tccagatttc acagctttag atcatcactt gaagttggtg caagtaggaa
     3841 ctcaaactgt tttcgaacaa actccagttg agttagctga acagggtgtt gtcttcacag
     3901 actttcactc agctttagaa gaaattccag agctgatcga agaattcttc atgtcatctg
     3961 ttaagtatga tgatgacaag ttggcggctt accacacagc ttactttaac agtggtgctg
     4021 tactctatat tccagataac gtagaaatca cagagccaat tgaaggaatt ttctaccaag
     4081 atagcgatag caatgtgccg tttaacaagc atattatgat tatcgctggt aaaaattcta
     4141 agattagtta tctggagcgt ttagagtcac gcggtgaagg aagtgacaaa gtaactgcca
     4201 atatcacagt ggaagtgatt gcacgttctg gtgcgcaagt caagtttgct gctatcgacc
     4261 gtctaggtga aaacgtcact gcctacatta gccgtcgtgg taaattaggc aacgatgcaa
     4321 gtattgactg ggctatcggt gtcatgaacg aaggaaatgt cgttgctgat tttgatagtg
     4381 acttgattgg taatggtagc catgctgacc tcaaggttgt agctctttca agtggtcgtc
     4441 aggtacaagg gattgatact cgtgtaacta actatggctg caactctatc ggaaatatcc
     4501 tacaacatgg ggttatcctt gaaaaagcaa ctttgacttt caatggtatc ggccacatca
     4561 tcaaggatgc taagggagca gatgcgcaac aagagagccg tgttctcatg ctttcagacc
     4621 aagcgcgttc agatgctaac ccaattcttt tgattgatga aaatgatgtc actgcaggac
     4681 acgcagcgtc tatcggacaa gttgatccag aagacatgta ttacctcatg agtcgtggat
     4741 tggataaggc aactgcagag cgtttggttg ttcgtggttt ccttggatct gttatcgtgg
     4801 agattccagt caaggaagtt cgtgatgaaa tgattgcaac tatcgaagag aaattgtcaa
     4861 aacgctaagg ggaagcctat gttagatgta gaagcgattc gcaaggattt tccaatttta
     4921 gatcagattg tcaatgatga acctctggtc tatctggaca atgctgcgac gacacaaaaa
     4981 ccactagtag ttctgaaagc tattaacagt tactatgagc aggacaatgc caatgttcac
     5041 cgtggtgtcc ataccttagc ggaacgagcg acagcttctt atgaagctgc tcgtgaaacc
     5101 attcgtaagt ttattaatgc aggctctaca aaggaagttc tctttaccag aggaacgaca
     5161 accagcctta actgggtggc acgctttgct gaggaaattc tcgctgaggg agaccgggtc
     5221 ttgatttcag taatggaaca ccattctaat atcattccat ggcaggaagc ttgtcgaaag
     5281 actggagcag agcttgtcta tgtctatctt aaagacggtg ccttggatat ggaggatttg
     5341 cgagctaaat tgactgataa ggttaaattt gtttccctag ctcatgcctc caatgttctt
     5401 ggtgtggtca atccgatcaa ggaaatcact caattagccc accaagttgg ggcaattatg
     5461 gtagtggatg gtgctcaatc tacacctcat atgaagattg atgtccagga cttggatctg
     5521 gactttttcg ccttttcggg tcacaagatg gctggtccga ctggtatcgg tgtcctttac
     5581 ggcaaagaaa agtatcttga gcaaatgtct ccagtagaat ttggcggcga gatgattgat
     5641 tttgtctacg agcaatttgc tagttggaag gaattgcctt ggaaatttga ggctggaacg
     5701 ccaaatatgg caggagctat tggacttgcg actgcagttg attatctgga aaagattggt
     5761 atggatgccg ttgaagctca tgaacaggaa ttgattgcgt acgtctatcc aaaactgcag
     5821 gcaattgagg gattgaccat ttacggttct caggatttgg ctcaacgttc gggtgttatt
     5881 gcctttaacc taggtgatct ccatcctcac gatcttgcga cggctctgga ttatgaagga
     5941 gtggctgttc gtgctggtca ccattgtgcg caacccttgc ttcagtattt ggaagtccca
     6001 gcaacagctc gtgcaagttt ttatatctac aataccaagg cagattgcga caaactagtc
     6061 gatgccctac aaaagacaaa ggagtttttc aatggcactt tctaaactag atagccttta
     6121 tatggcagtg gtagcagacc attcgaaaaa tccacatcac caagggaagt tagaagatgc
     6181 tgagcaaacc agtctcaaca atccgacttg tggggatgtc atcaacctct ctgtcaagtt
     6241 tgatgcagag gaccgtttgg aagatattgc ttttctaaat tcaggatgca cgatttcaac
     6301 tgcttctgct agtatgatga cagatgccgt tttaggaaaa accaaacaag aaattttaga
     6361 actggcgact attttttctg aaatggttca agggcaaaaa gatgagcgtc aaggccaact
     6421 tggagacgcg gcattcttgt caggtgttgc caaattccct caaagaatca agtgtgcaac
     6481 cctagcttgg aatgccctta agaaaacaat tgaaaatcaa gaaaaacagt aagacaagtt
     6541 tcttttgtct tatgaattat tagaaatgaa gaaagaaagg atactatggc tgaagaaaga
     6601 gtagaaccaa aaccaattga ccttggtgaa tataaatttg gtttccatga cgatgtagag
     6661 cctgtcttat cgacaggaaa aggactcaac gaaggtgtta ttcgtgaatt atctgctgct
     6721 aagggtgagc ctgagtggat gttggagttc cgtttgaagt cttatgaaac cttcaaaaaa
     6781 atgcccatgc aaacttgggg agcagacttg tcagagattg actttgatga cttaatctac
     6841 taccaaaaac catctgacaa accagcccgt tcttgggatg atgtacctga aaagattaaa
     6901 gaaacctttg aacgtatcgg gattccagaa gctgaacgtg cttatttagc aggggcttct
     6961 gcccagtacg agtcagaagt ggtttaccac aacatgaagg aagagttcca aaaattaggt
     7021 attatcttta cagatacaga ttccgcactc aaggaatacc cagacttatt taaacaatac
     7081 tttgcgaagt tggtaccgcc gacagataac aagttggcag ccctcaactc agcagtatgg
     7141 tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg tagatattcc acttcaaact
     7201 tatttccgta tcaataacga aaatataggt cagttcgaac gtaccttgat tatcgttgat
     7261 gagggagcaa gcgtccacta cgtagaagga tgtacagcac caacatattc aagcaatagc
     7321 ttacacgctg ccattgtaga aatttttgct ttggacggag cttatatgcg ttatacaact
     7381 atccaaaact ggtctgataa cgtctataac ttggtaacaa agcgtgctaa ggctcaaaag
     7441 gatgccactg ttgagtggat tgatggaaac ttgggtgcca aaacgactat gaaatatcca
     7501 tctgtttacc ttgatggaga aggagcgcgt ggtaccatgc tctctatcgc ctttgctaat
     7561 gcagggcaac accaagacac gggtgctaag atgattcaca atgctccaca taccagctcg
     7621 tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg ttgactaccg tggacaagtc
     7681 acctttaaca agaactctaa gaaatctgtt tcccacattg aatgtgatac cattatcatg
     7741 gatgacttgt cagcatcaga tactattcca tttaatgaaa ttcacaactc gcaagtggct
     7801 ttggaacacg aagccaaagt atctaagatt tcagaagagc aattgtatta tctcatgagc
     7861 cgtggattgt cagaatctga ggcaactgaa atgattgtca tgggatttgt agaacccttt
     7921 acaaaagaac ttccaatgga atacgcagtt gagctgaacc gcttgattag ctatgaaatg
     7981 gagggatcag ttggataaaa tttgatttta tactcttcga aaatctcttc aagccacgtc
     8041 agcatcgcct taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
     8101 cagtgttttg agcaacctgc ggctagcttc ctagtttgtt ctttgatttt gagtattaga
     8161 tttactcaaa atcaaggatt ttgaagatga acttgtatca aaaaatcgcg gtttaaaatc
     8221 gcgatttttt ataatttctc gttaacaaag cggacaaact gattccacca aacttttaag
     8281 aagaaggctt tttcaatttt cttgtctgct accatttcga aactagggcg ctctgtggtg
     8341 atgtaacctt gaccaatcaa gtccttgtct tcataagtca aatggccaac cactgttcca
     8401 gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga attgaacaga ttgggaagat
     8461 tgattcccaa tctgttcgat tagatagata tcctctggag ccactgcagt tactgtatct
     8521 tcttttccat cttgtacagg ggctttgcta tcttgatagg catcgccttg ttgaacgatt
     8581 ttgcgaagtg taaatgtaga agaaatataa tccattaggg aagatgtagc tgtaaatcga
     8641 gcgtaaggat tattgtcttg atgatctgca tttaaaacaa ctgtgatgac tctcatgcct
     8701 ttttcgacag tagtaccaac aaaagactct ccagccttat ctgttgttcc tgtttttagc
     8761 ccatcaaaac caccacggta agcaggcata ccttctaaca tgtagttggt tgaagtgatt
     8821 gtcatcccag caaaagtaga agaaggtttt ttggtgattt ctaagacttg tgggtatttt
     8881 ttgatgaggt tgcgagcaac gatagcgaca tcataagcac taagcttatt ttcctcatct
     8941 tttttagaac ctgggtaaat gttatcccct agagtttcat tgttaagacc tgtcgtattg
     9001 acaacagtgg catcctgaat tccccattcc aagagttttg cccgcatcat atcgacgaaa
     9061 tctttttctg agccagcaat tttctcagct agggcaatag cggcgctgtt ggcactagat
     9121 accagagttg cttcaagcaa ctcttcgaca gtataattac gggcctccat aggaatatta
     9181 ctggcttcag aatttgtcgt caattgataa ggataatcag aaatatctac aggagtggag
     9241 agggtaatac ttccgttttc caaagcttca tagaccagat aaacagtaat caattttgtt
     9301 atggaagcaa tttcgacagg ttgcgttgca tccttctcat agagaatttt accagtattt
     9361 gcctcaacag caatcgcatg tttagcggca atggtaaaat cttgagcaac agcagtagaa
     9421 gcacccccta aaagagagac agttaacaaa gttaaaaata tttttttcat agtagtctta
     9481 ttctatcata aagaaaaaaa atattcttgc tttaataatt catctgttaa gctttttgaa
     9541 aatatggtaa aataaagtga gggaggtaac tcatgtttcg tagaaataaa ttattttttt
     9601 ggaccacaga aattttactc ttaaccatca tcttttacct atggagacag atggggtctt
     9661 tgattaaccc ttttgttagc gtgcttaata caattatgat tccattttta ttaggggtct
     9721 ttctttatta tttgacaaac cctattgtta ctttcttaaa taaagtctgt aaactcaatc
     9781 gtttgcttgg tattttaatt accttgtgta ctttggtctg gggaatggtc ataggtgttg
     9841 tctatctctt acctattttg attaatcagt tatctagttt gattatatct agtcaaacta
     9901 tttatagtcg agtacaagac ttaatcatag acttatctaa ttatcctgcg ctccagaatt
     9961 tggatgtaga agctacaatt cagcagttaa acttatccta tgttgatatt cttcaaaata
    10021 tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc agctcttatc agtactgttt
    10081 tgattttgat tatgactcca gtttttttgg tttatttctt attagatgga cataaattct
    10141 tgcccatgct tgaaagaacg attctaaaga gggatcgctt gcatattgca ggcttattaa
    10201 agaatttaaa tgcgacgatt gctcgctata ttagtggagt ttcgattgac gcaatcatta
    10261 taggttgttt agcttatatt ggctatagta ttattggttt aaaatatgct ttagtttttg
    10321 ccattttttc tggtgtagcc aatttaattc cttatgtggg gccaagtatt ggtttgattc
    10381 ctatgatcat cgcaaatata ttcactgatc cccatagact gctgattgca gtgatttata
    10441 tgcttgttgt tcagcaggta gatggcaata tcttatatcc tcgaatcgta ggaagtgtta
    10501 tgaaggttca tccaatcacg attttagttt tacttttgtt gtcaagcaat atttatggtg
    10561 tagttggaat gattgtcgca gtgccaacct attctatctt gaaagaaatt tctaagttct
    10621 tatcccgttt gtatgaaaat cataaaataa tgaaagaacg agaaagagaa ttagctaagt
    10681 aaaagtcagg agaaccctga tttttcttta ctggaagtgg cctttagatt agaagactga
    10741 aaataagtta aagtcttaaa ctaattttca cagctaagaa tagtagaagt taatctgata
    10801 aaaatcgaaa aaaccagtgg aattctgtgt cagggtaagt tccactggtt ttcatagtct
    10861 attaaagttc gaatgaaacc tatttatagt agattgaaac tagaatagta cacctctaat
    10921 tctaaaacat tgttagaaat cgatttgact gtcctgatct attcgtccta ttcttatttc
    10981 attttactat attttggtgc aataagtgaa aagtagtccg aataatataa ggattgattt
    11041 tatagttttt aaactcaaat gaattaaaat aaagagagta cgaaaattct catctgaaag
    11101 tattttagaa taattctctt cgtgaatttc ttcaaaacag atagcttcat cttaggtatg
    11161 tgttaattgg atttcgtaag ctctatttac aatcgtaaag ttatgcactg agaaagttgt
    11221 agttagtctt ccagtttgct aaatttctcg aatagtatct tttttaggta tgtgatttct
    11281 ttttgcattt ttgagttaga taaggtataa tggttttatt gtcttttggg gtcgttacgg
    11341 attcgacagg cattatgagg catattttgc gactcgtgtg gcgacgtaaa cgctcagtta
    11401 aatataactg caaaaaataa cacttcttac gctctagctg cctaaaaacc agcaggcgtg
    11461 acccgatttg gattgctcgt gttcaatgac aggtcttatt attagcgaga tacgattaag
    11521 ccttgtctag cggcttgata agagattgat agactcgcag tttctagact tgagttatgt
    11581 gtcgaggggc tgttaaaata atacataacc tatggttgta gacaaatatg ttggcaggtg
    11641 tttggacgtg ggttcgactc ccaccggctc cattattcct ttgcattctt ttgcattcct
    11701 tggtaaaacg ttgttaaatc aacgtttttt atttttatct ttggtattcc tttgcattct
    11761 tttgctaaaa agggagtcac aaacagaccc tattttaaaa aaggatacaa catttgttgc
    11821 atcctaaaaa taatcttttt tcgacggaag acatgggatt cgaacccacg cacgctatta
    11881 cacgcctacc gcgtttccaa cacggcctct taagcctctt gagtaatctt ccaatactta
    11941 ctcaaatagt ctaccataaa ggctcttatc ttgcaataaa aattctagaa ataagaaaaa
    12001 tgatagattt tgaaagaaaa tgataaaaaa tgcttgactt cgaaataaag tatggtagaa
    12061 tgaatagtgt aaacgataac aggaggtgat tcagtgttaa aaacagaacg taaacaactg
    12121 attctagagg agttaaatca acatcatgta gtttctctag aaaaattagt tagtttgcta
    12181 gaaacgtcag aatcaacggt tcgaagagac ttggatgagt tggaagcgga aaacaagctt
    12241 cgtcgtgtgc atggtggagc agaactcccc cactccttac aggaagaaga aaccattcaa
    12301 gaaaaatctg tcaaaaacct tcaagaaaag aagttgctgg ctcagaaagc agcctctctc
    12361 attaaagaaa aagatgtcat ctttatcgat gctggaacaa caactgcttt tttgattcat
    12421 gaattggtca ataagaatgt tacagttgtg accaactcca ttcaccatgc cgctcagttg
    12481 gttgaaaagc agattccaac tgtcatggtt ggaggaaacg tcaagacggc gacagatgct
    12541 agtatcgggg gcgttgctct taaccagatt aaccaattgc actttgaccg tgcctttatc
    12601 ggaatgaatg gtgttgacga tggctattat acgactcctg atatggagga gggagctgtg
    12661 aaaagagcta ttttggagaa tgccaagcag acctacgtct tggtggattc gtcaaaaatt
    12721 ggacaaactt gctttgccaa ggtagcacca ctcaaacgcg ctatcgttat cactagtcaa
    12781 gggcatgagc tcttgcaggt tattaaggag aaaacggagg taatagaagt atgatttata
    12841 cagtcacact caatccatcc attgactata tcgttcgttt ggaccaagtc aaagttggta
    12901 gtgtaaatcg tatggacagt gatgataagt ttgctggtgg gaaaggaatc aatgtcagcc
    12961 gtgtcttgaa acgtttgaat ataccaaata cagcgacggg atttatcggt ggctttactg
    13021 gtaaatttat cacagatact ttagcagagg aagaaatcga gacacgtttt gtccaggtgg
    13081 cagaagatac tcgtatcaat gttaaaatca aagcagacca agaaacagaa atcaacggaa
    13141 cgggtccaac tgttgaatcg gttcagctag aagaattgaa agctatttta tctagtctga
    13201 cagcagaaga tacagttgtc tttgcaggtt caagtgctaa aaatctaggc aatgttatct
    13261 ataaggattt gatttccttg acgcgccaga ctggtgcgca agtggtctgt gactttgaag
    13321 gacagacctt aattgatagt ttggactacc agcctcttct tgtaaaacca aacaatcatg
    13381 aacttggagc gatttttggg gttaaactcg aaagtttaga tgaaattgag aaatacgctc
    13441 gtgagttact ggctaagggt gctcaaaatg ttattatctc tatggctggt gatggtgccc
    13501 ttcttgtcac atctgatgga gcttacttcg ctaaaccaat caagggaaca gtcaaaaatt
    13561 cagttggagc tggtgattct atggttgctg gattcacagg tgaatttgtc aaatcaaaag
    13621 acgcagtaga agccttcaaa tggggagtgg cttgcggaac ggcaactacc ttctcagatg
    13681 acttggcaac ggcggaattt attaaagaaa catatggaaa agttgaggta gaaaaacgat
    13741 gaaaattcaa gacctattga gaaaagatgt catgttgcta gatttgcagg caactgaaaa
    13801 aacagctgtc atcgacgaga tgattaaaaa tttgacagac cacggttatg taacagattt
    13861 tgaaacattt aaagaaggca ttttggcgcg tgaagctttg acttctactg gtttgggtga
    13921 tggaatcgca atgcctcaca gcaaaaacgc tgctgtcaaa gaagcgacag ttctatttgc
    13981 taagtcaaat aagggtgttg actacgagag cttggatgga caagcaactg acctcttctt
    14041 catgattgca gctccagaag gtgccaatga tactcacttg gcagccttgg cagaattgtc
    14101 tcaatacttg atgaaagacg gttttgcaga caaacttcgt caagcaacat ctgcagacca
    14161 agttatcgaa ctttttgacc aagcttcaga aaaaactgag gaacttgttc aagcacctgc
    14221 taatgactct ggtgacttta tcgtagctgt tacagcttgt acaacaggta ttgcccacac
    14281 ttacatggcc caagaagccc ttcaaaaagt agctgctgaa atgggggttg gtatcaaggt
    14341 cgaaaccaac ggtgctagcg gtgttggaaa tcaactaact gcagaagata tccgtaaggc
    14401 taaagctatt atcattgcag cagacaaggc cgttgaaatg gatcgatttg atggaaaacc
    14461 attgatcaat cgtccagttg ctgacggtat ccgtaagaca gaagagctaa ttaacttggc
    14521 tctttcagga gatactgaag tctaccgtgc cgctaatggt gccaaagctg caacagcctc
    14581 taacgaaaaa caaagccttg gtggtgcctt gtacaaacac ttgatgagtg gtgtatctca
    14641 aatgttacca ttcgttatcg gtggtggtat catgattgcc cttgccttct tgattgacgg
    14701 tgctttgggt gttccaaatg aaaaccttgg caatcttggt tcttaccatg agttagcttc
    14761 tatgttcatg aaaattggtg gagctgcctt tggtttgatg cttccagtct ttgcgggtta
    14821 tgttgcctac tctattgctg aaaaaccggg tttggtagca ggtttcgtgg ctggtgctat
    14881 tgccaaagaa ggttttgcct ttggtaaaat tccttatgcc gcaggtggtg aagcaacttc
    14941 aactcttgca ggtgtctcat ctggtttcct aggtgccctt gttggtggat ttatcgcagg
    15001 tgccttggtt cttgccatca agaaatacgt taaagttcct cgttcactcg aaggtgctaa
    15061 atcaatcctt ctattgccac ttcttggaac aatcttgaca ggatttgtta tgctagctgt
    15121 gaatatccca atggctgcaa tcaacactgc tatgaatgac ttcctaggcg gtcttggagg
    15181 aggttcagct gtccttcttg gtatcgtcct tggtggaatg atggctgttg acatgggtgg
    15241 accagttaat aaagcagctt atgtctttgg tacaggtacg cttgcagcaa ctgtttcttc
    15301 aggtggttct gtagccatgg cagcagttat ggctggagga atggtgccac cacttgcaat
    15361 ctttgtcgca actcttcttt tcaaagataa atttactaag gaagaacgta actctggttt
    15421 gacaaacatc atcatgggct tgtcatttat cactgaggga gcgattccat ttggtgccgc
    15481 tgacccagct cgtgcgattc caagcttcat ccttggttca gcagtagcag gtggactcgt
    15541 tggtcttact ggtatcaaac tcatggcgcc acacggagga atcttcgtta tcgcccttac
    15601 ttcaaatgct ctcctttacc tcgtttctgt cttggtagga gcaatcgtaa gtggtgtggt
    15661 ttatggttac ctacgcaaac cacaagcata aaaaatagaa aaatgaaaag attggaccgt
    15721 ttggtgcagt ctttttctct tcccgaaatg cctgtgaaat atggtataat agaagaatgg
    15781 caaacaagaa tacaagtaca acaagacgga gaccgtctaa agcagaactg gaaagaaaag
    15841 aagcgattca acgaatgttg atttcattag gaattgcgat tttattgatt ttcgcagtct
    15901 tcaaattagg ggctgcaggt ataacccttt ataatttaat tcgcttgcta gtgggtagcc
    15961 tagcttatct ggcgatattc ggcctattaa tctatctctt ctttttcaag tggatacgaa
    16021 aacaggaagg actcttatct ggctttttca ccatatttgc tggcttactc ttgatttttg
    16081 aagcctactt ggtttggaaa tatggtttgg acaagtccgt tctaaaaggg accatggctc
    16141 aggttgtgac agatctgact ggttttcgaa cgactagctt tgctggaggg ggcttgatag
    16201 gggtcgctct ttatattcca acagcctttc tcttttcaaa tatcggaact tactttattg
    16261 gttctatctt gattttagtg ggttctctcc tagtcagccc ttggtctgtt tacgatattg
    16321 ctgaattttt cagtagaggc tttgccaaat ggtgggaagg gcacgagcgt cgaaaagagg
    16381 aacgctttgt caaacaagaa gaaaaagctc gccaaaaggc tgagaaagag gctagattag
    16441 aacaagaaga gactgaaaaa gccttactcg atttgcctcc tgttgatatg gaaacgggtg
    16501 aaattctgac agaggaagct gttcaaaatc ttccacctat tccagaagaa aagtgggtgg
    16561 aaccagaaat catcctgcct caagctgaac ttaaattccc tgaacaggaa gatgactcag
    16621 atgacgaaga tgttcaggtc gatttttcag ccaaagaagc ccttgaatac aaacttccaa
    16681 gcttacaact ctttgcacca gataaaccaa aagatcagtc taaagagaag gaaattgtca
    16741 gagaaaatat caaaatctta gaagcaacct ttgctagctt tggtattaag gtaacagttg
    16801 aacgggccga aattgggcca tcagtgacca agtatgaagt caagccggct gttggtgtaa
    16861 gggtcaaccg catttccaat ctatcagatg acctcgctct agccttggct gccaaggatg
    16921 tccgaattga agcaccaatc cctgggaaat ctctaatcgg aattgaagtg cccaactccg
    16981 atattgccac tgtatctttc cgagaactat gggaacaatc gcaaacgaaa gcagaaaatt
    17041 tcttggaaat tcctttaggg aaggctgtta atggaaccgc aagagctttt gacctttcta
    17101 aaatgcccca cttgctagtt gcaggttcaa cgggttcagg gaagtcagta gcagttaacg
    17161 gcattattgc tagcattctc atgaaggcga gaccagatca agttaaattt atgatggtcg
    17221 atcccaagat ggttgagtta tctgtttaca atgatattcc ccacctcttg attccagtcg
    17281 tgaccaatcc acgcaaagcc agcaaggctc tgcaaaaggt tgtggatgaa atggaaaacc
    17341 gttatgaact ctttgccaag gtgggagttc ggaatattgc aggttttaat gccaaggtag
    17401 aagagttcaa ttcccagtct gagtacaagc aaattccgct accattcatt gtcgtgattg
    17461 tggatgagtt ggctgacctc atgatggtgg ccagcaagga agtggaagat gctatcatcc
    17521 gtcttgggca gaaggcgcgt gctgcaggta tccacatgat tcttgcaact cagcgcccat
    17581 ctgttgatgt catctctggt ttgattaagg ccaatgttcc atctcgtgta gcatttgcgg
    17641 tttcatcagg aacagactcc cgtacgattt tggatgaaaa tggagcagaa aaacttcttg
    17701 gtcgaggaga catgctcttt aaaccgattg atgaaaatca tccagttcgt ctccaaggct
    17761 cctttatctc ggatgacgat gttgagcgca ttgtgaactt catcaagact caggcagatg
    17821 cagactacga tgagagtttt gatccaggtg aggtttctga aaatgaagga gaattttcgg
    17881 atggagatgc tggtggtgat ccgctttttg aagaagctaa gtctttggtt atcgaaacac
    17941 agaaagccag tgcatccatg attcagcgtc gtttgtcagt tggatttaac cgtgcgaccc
    18001 gtctcatgga agagcttgag atggcaggtg tcattggtcc agctgaaggt accaagccaa
    18061 gaaaagtatt gcagcaataa aaaatagctt ctttccaagt ttggaaggag gctattttag
    18121 tgattattga ttagttttat tttccgaagt tggggtattg gactgttttt cgttttcagt
    18181 agcaggttta cttggagtag gagcaggagt agaagaatcc tgagttgatg ttttctgctc
    18241 ttcttttttc tcttccttga cgctggattt tggcgtttct tcttgttgtg ttttttcttg
    18301 agaagtctta ttttccttat tgggactagt attttcctga ggggattcct tttgaatttc
    18361 tttgacaatt gttgtcgtct ggcttgttgt aggttccttt ttagtatttt tgttattatc
    18421 caaggcgttc ataatcgtga tactagcggt aatcaagcca aggatactag cgatagtcgc
    18481 aacggttttt tgaaagactg taaagccttt tttgatgtgt tctgtttttg gttttgaagt
    18541 tctacgataa ttagacatac attctctcct ttaattaaaa tttattatac ctcatttctt
    18601 taaaaaaatc ttaaaaaaag aggagatttt tctacacgaa cttcagtaat tagttgaaat
    18661 aaaatatgac ttatgatata acaaaataaa gaaagcgatt tcaaaaaagg agggcgttat
    18721 atgttcgaaa ttagaaattt gagtctctct tttgcaggca ggcggttgct agagccaaca
    18781 gatttgatat ttgaaagggg aaaagtatat acaatatatg ggaagtcagg cgtaggaaag
    18841 tcttctttac tgaataaaat tggtttgctc tctgctacgg atcctagtgt ttcttatttc
    18901 ttcgatggaa aagagattga tatcgaaaat aagaaatcag tctctgtctt tatagctgaa
    18961 gaagttgcct ttgtatttca ggggcgaaat ctaataaatg atttgaccgt atttgaaaat
    19021 ttaagactag ctttaaactt ttatgacttg agtccagatg aaatagaaag caaaattgat
    19081 acagtattgg cggatttaca gatttcttct ttaaagcatg cttatccaga agatttatcc
    19141 ggtggtgaag aacaacgagt ggcaatcgca agagccttag ttacaggaaa gactctcatc
    19201 ttagctgatg aaccaacaag ttctttggat aaagaaaata gagaaaaaat ctccgccttg
    19261 ttaattgatt tagctcacaa atatcataaa attgtattga ttgtttcgca tgatgaggcg
    19321 atgattgcaa taggagatgt tcagcttcat tttaaagacc ataaattagt tgggaattgt
    19381 cttattttga attctgatga agggataaag gattctaaga agtggtcctc ctgtttgtcg
    19441 tcttctcata cgaagctatc cgttttgaaa catagaaggc cttttttacc tagattatta
    19501 gcgtttttta tctctcttgt agttgctata gcagtaacct ctattaactt tcagtcctta
    19561 tttgcagata agtatcacca actggtgaac aactcactcg aaaatggctt cttggtgatt
    19621 aatgattcgc ttcatttaca aactacaaaa gtgttggatg attttctcag ttttgataag
    19681 gaggaaatca cctcaattag cacaagtcag aatattcaaa ccgtcaatcc ttatatagag
    19741 tttctctctt tgggtatgac gtttgataat tcaaaagact attcacaact tcaaaagaac
    19801 tttcagccaa ctttgactat tgatggtcag accagaagct tgacaagaaa tttttcaatt
    19861 caacccttgt atcagacaaa tacaacacag aggcagatag agtattttga taggagcaat
    19921 gaaaaaggga tttatctatc tgagcaattc atttcagatg aaaaattacc aaatatagtt
    19981 tcgggaacta ccgtgacact gactttttat attccaattt ctttatatga atcaagtata
    20041 gagaaagagg ggaatatatt gaaaggagat ggcggtttat ttgtcaaagt ggataaaaca
    20101 tatcctgttt tagggattgt taaaaaaagt tatccgtttg aatattcccc ttatgggaac
    20161 accctattta tgaatattgc tgaaatggaa gaattgcaaa atgaagcaat tcaacagcat
    20221 cccatgacga agatggcttt agatggtttt cctttgaaat catggatgcc gagtgcgatt
    20281 catgtgttac taaaggatag cggtgctatt cctgaagaat tgagtagaat aagagcaatc
    20341 tcttcacaaa ttactatttt atcatcatat gaaaactacg aagaatttaa taaaggactc
    20401 acctatatca ggcaattttt aatgttgcta tccctagtct tactcatcct tgtcatcgca
    20461 gtattgtcct ttgttttctt tttgctcaat cgtcctcgac gctttgaagt agggatttta
    20521 aaatctttgg gatacagtac tcaaaatatt gtttggcttt tcttaaaaga attaattggt
    20581 tatggtaaaa caatttcgat attagcaagt tgtttactcg tcattctttc cattttagca
    20641 atgcaagtgc ttaaattgga aatttcagat gtttttaaat tctatctaac ttccgttttc
    20701 accttaattg gattatcagt ctcagtactg ataataagtg gcttactacc tatatacaca
    20761 acttgtaggc aaacagttgt cgatactatc cgaaagaatg gatgaggtga tatcatgaaa
    20821 cataagataa tgaaaaaaat aatagtggta gtgtttgcta tcccatggtt aacattttta
    20881 agtcaagtac atgcagatta tgtaagtaag tctagttctt tagacggtta tagcttggta
    20941 ggcttgaatg ttcttaatgt gacttttaat gcttctggct attctgatac ttatagtggc
    21001 agtgtgtcaa atatgtattt cactgactgg gcttggtttc ctaatacgat aagtaatcgt
    21061 tccacttgga aaagttcgat tccatatggt caacgcgcaa atggtacagt ccatataggt
    21121 gtaggagtaa attcgccttg gggagcggtt aatctctggg gcggacaaaa ttacttttct
    21181 ttagattttt aacagaaata atcaaagtta gatagaatga ataagaatgc tcttgatgat
    21241 ggtatcaaga gtattttatg ttattcagat taatgcaaac attgcccttt cttgtcgcag
    21301 gctccgtttc atgatacaat agaaggagtg attttagaaa gcgtgagaaa catgatttac
    21361 tttgataatt cggcgacgac caggccctat ccagaagccc ttgaaaccta tatgcaggtg
    21421 gcttcaaaaa ttttaggaaa tccatctagt ctccatcgtt tgggagacca ggcaacacga
    21481 attttagatg cttcccgtca acagattgca gatttaatcg gtaagaaaag tgatgaaatc
    21541 ttctttacat ctggtgggac agaaggggat aactggatca tcaagggagt agcatttgaa
    21601 aaagcccagt ttggcaagca catcatcgta tcagccattg aacatccagc agttaaggaa
    21661 tcagccctct ggttgaaagc tcaaggtttt gaagtggatt ttgctccagt tgataacaaa
    21721 ggatttgtgg atgttgaggt gctagaagat ttgataagac ctgatacgac cctcgtttcc
    21781 atcatggcag ttaacaatga aattggctct gttcagccca ttgaggctat ttcaaaacta
    21841 ttggcagaca agccaactat ttccttccac gttgatgcgg ttcaggcgct tgccaagatt
    21901 ccgactgaaa agtatctgac agaacgagtg gatttcgcga ctttctctgg tcacaagttc
    21961 cacggaatcc gtggtgttgg ttttatctat atcaagtctg gcaagaagat tacgcctctt
    22021 ttaacaggtg gtggtcagga acgtgattac cgttcgacaa ctgaaaatgt ggcaggaatt
    22081 gcagcgaccg ctaaggctct ccgtttatct atggaaaagc tagatatctt taggagcaag
    22141 actgggcaga tgaaggcagt gattcgtcaa gcacttctgg actatccgga tatatttgtc
    22201 ttttcagatg aggaagactt cgcccctcat attctgactt ttggaatcaa gggtgttcgt
    22261 ggtgaggtca ttgttcacgc ctttgaagac tatgatattt tcatctcaac gacctcggct
    22321 tgttcgtcca aggctgggaa accagccgga accctgattg ctatgggagt ggacaaggat
    22381 aaggctcagt cagctgtgcg tcttagtcta gaccttgaaa atgatatgag tcaggtcgag
    22441 cagttcttga ccaagctaaa attaatttac aatcaaacta gaaaagtaag ataggagcat
    22501 tcatgcagta ttcagaaatt atgattcgct acggtgagct gtcaaccaag ggcaaaaatc
    22561 gtatgcgttt catcaataaa cttcgcaata atatttcaga cgttttgtct atctatcccc
    22621 aagttaaggt aacagcagat cgcgaccgtg cccacgctta cctcaatgga gcagattaca
    22681 cagcagtagc agaatcgctc aaacaagtat ttggaattca aaacttttcc cctgtttata
    22741 aggttgaaaa atctgtagaa gttctgaagt ctgctgtcca agagattatg caggacatct
    22801 acaaggaagg catgaccttt aaaatctcta gcaagcgtag cgaccacacc tttgaattgg
    22861 acagtcgtga actcaaccaa acgcttggag gggctgtatt cgaagccatt ccaaacgtac
    22921 aagctcaaat gaaaagtcct gacatcaatc ttcaggtgga gatacgtgaa gaagcagcct
    22981 atctttctta tgaaaccgtt cgaggggcag gtggattacc agtgggaact tctggtaagg
    23041 gcatgctcat gttgtcaggg ggaatcgatt cccctgtagc tggctatcta gcgcttaaac
    23101 gaggggtaga tatagaggca gttcactttg ccagcccacc ttacacgagt cctggtgctc
    23161 ttaaaaaagc ccaagatttg acccgtaaat taaccaaatt tgggggaaat atccagttta
    23221 tcgaagttcc ttttacagag attcaagagg aaatcaaagc caaagcgcca gaagcctacc
    23281 ttatgacctt gacgcgtcgt tttatgatgc gtattactga ccgtattcgt gaggtacgaa
    23341 atggtttagt tatcatcaat ggggaaagtc taggtcaagt agccagccaa acccttgaaa
    23401 gtatgaaggc tatcaatgct gttaccaaca ctcccatcat tcgtcctgtg gttaccatgg
    23461 acaagttgga aatcattgac atcgcccagg aaatcgatac ctttgacatt tcaatccaac
    23521 cgtttgaaga ctgttgtacc atttttgcac cagatcgtcc aaaaacaaat cctaaaatta
    23581 agaatgcgga gcagtacgaa gcgcgtatgg atgttgaagg cttggttgag cgagcagtgg
    23641 ctggaatcat gattactgaa atcacacctc aagccgaaaa agatgaagtt gatgacttga
    23701 ttgacaatct gctctaattc agaaaatcca aaagaatagc gaaaatcagt aaaaaaagtt
    23761 agttttttct ctaaaaacag gtaaaaaact aacttttttt atttttatga tataatgata
    23821 taaaattttg aatatagaga gttttctgac aatgaatcaa tcctactttt atctaaaaat
    23881 gaaagaacac aaactcaagg ttccttatac aggtaaggag cgccgtgtac gtattcttct
    23941 tcctaaagat tatgagaaag atacagaccg ttcctatcct gttgtatact ttcatgacgg
    24001 gcaaaatgtt tttaatagca aagagtcttt cattggacat tcatggaaga ttatcccagc
    24061 tatcaaacga aatccggata tcagtcgcat gattgtcgtt gctattgaca atgatggtat
    24121 ggggcggatg aatgagtatg cggcttggaa gttccaagaa tctcctatcc cagggcagca
    24181 gtttggtggt aagggtgtgg agtatgctga gtttgtcatg gaggtggtca agccttttat
    24241 cgatgagacc tatcgtacaa aagcagactg ccagcatacg gctatgattg gttcctcact
    24301 aggaggcaat attacccagt ttatcggttt ggaataccaa gaaaaaattg gttgcttggg
    24361 cgttttttca tctgcaaact ggctccacca accgctatat cgagtgccag aaactatcgc
    24421 ctgaccaacg catcttcatc tatgtaggaa cagaagaagc agatgataca gacaagacct
    24481 tgatggatgg caatatcaaa caagcctata tcgactcgtc gctttgctat taccatgatt
    24541 tgatagcagg gggagtacat ctggataatc ttgtgctaaa agttcagtct ggtgccatcc
    24601 atagtgaaat cccttggtca gaaaatctac cagattgtct gagatttttt gcagaaaaat
    24661 ggtaagttaa gaaaggaaaa aacgaaatgc atattgaaca tcttagccac tggagtggtc
    24721 atcctaaccg tgaaatgtac cttaaccgtt atggacatgg tgggattcca gttgtggtct
    24781 ttgcttcatc aggtggtagt cacaacgaat actatgattt tggcatgatt gatgcctgtg
    24841 cttcctttat cgaggaaggc cgtgtccagt tctttaccct atctagtgtg gatagtgaga
    24901 gctggttggc tacttggaaa aatgctcatg accaagcgga aatgcaccgt gcctacgaac
    24961 gttatgtgat tgaggaggcc attcttttat caagcacaag acaggttagt ttgatggcat
    25021 gatgacgaca ggttgctcta tgggagccta tcatgcactc aatttcttcc tccagcatcc
    25081 agatgtcttt accaaagtga ttgctctcag tggtgtttac gacgcacgtt tctttgtcgg
    25141 tgattactac aacgatgatg ctatttacca aaactcgcca gtagattata tttggaacca
    25201 aaacgatggc tggtttattg accgttaccg tcaggcagag attgtgctgt gtacggggct
    25261 tggagcctgg gaacaagatg gtttaccatc cttttacaag ctcaaagaag cctttgacca
    25321 gaaacaaatt ccagcctggt ttgctgaatg gggacatgat gtcgcccacg actgggaatg
    25381 gtggcgtaaa caaatgcctt atttcctcgg taatctctat ttataaaagg agttacctat
    25441 gaattacctt gttatttctc cctactatcc acaaaacttt caacagttta ccatcgaact
    25501 agctaataaa ggcatcacag tcttgggaat tggtcaagag tcttacgagc aattggatga
    25561 gcccttgcgc aatagcttga ccgagtattt tcgtgttgat aatcttgaga acatagatga
    25621 agtcaaacgt gcagttgctt ttctctttta taaacatggt ccaattgacc gcatcgagtc
    25681 tcacaatgaa tactggcttg agctagacgc aacactcaga gaacaattca atgtttttgg
    25741 tgccaaacca gaggatctca aaaagacgaa atataagtct gaaatgaaga aacttttcaa
    25801 aaaagcaggt gttcctgtgg tacctggagc tgttatcaag acggaagcag atgttgatca
    25861 agcagtgaaa gaaatcggtc ttccaatgat tgccaaacct gataatggag tgggagcagc
    25921 cgcaaccttt aaacttgaga cagaagacga tatcaatcac ttcaagcaag aatgggacca
    25981 ttcaaccctt tatttctttg aaaaatttgt cacttccagc gaaatctgta cctttgacgg
    26041 gctcgtggac aaggatggaa agattgtctt ctcaacaacc tttgactacg cctatacacc
    26101 gcttgacctc atgatttata agatggacaa ttcttattat gtgctcaagg atatggatcc
    26161 taaactgcgc aagtatgggg aagcaattgt caaagaattt ggtatgaaag aacggttttt
    26221 ccatattgag ttcttccgtg agggggacga ttatattacc atcgagtaca ataaccgccc
    26281 tgcaggtggt tttaccattg atgtttataa ctttgctcat tccttggacc tttatcgtgg
    26341 ctatgcagct attgtcgcag gagaggagtt cccggcgtca gactttgaaa ctcagtattg
    26401 tttggctact tctcgccgtg caaatgctca ctatgtttat tcagaagagg atttgcttgc
    26461 caaatatagc cagcagttca aggttaaaaa agtcatgcca gctgccttcg cggaacttca
    26521 aggagattac ctgtatatgc tgacaactcc gagtcgacaa gaaatggatc agatgattgc
    26581 tgatttcgga caacgtcaag aataagaact atcggattaa ggaaattcac tcccttaatc
    26641 cttttgtttt gtctggtaaa aaataagagc atcctaacaa ggtagctatc ataaaacttg
    26701 ttcgataact atttgaagca ggattaggtg gctagaaatt gaattttaac atttcaattt
    26761 agtcatagta ttgtgttttc gtatccttaa atcagctaaa aggatccatg acgacaccta
    26821 tacgatatag ttttcaggat accaaaccag tctattaata ctcaatgaaa atcaaagagc
    26881 aaactaggaa
//
LOCUS       DBEJZJ010000027        26373 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000027 DBEJZJ010000000
VERSION     DBEJZJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.27"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..134)
                     /locus_tag="ACL3R8_001432"
     CDS             complement(<1..134)
                     /locus_tag="ACL3R8_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR1314294.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLDFLR
                     "
     gene            complement(359..1219)
                     /locus_tag="ACL3R8_001433"
     CDS             complement(359..1219)
                     /locus_tag="ACL3R8_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR1314295.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1235..2512)
                     /gene="spxR"
                     /locus_tag="ACL3R8_001434"
     CDS             complement(1235..2512)
                     /gene="spxR"
                     /locus_tag="ACL3R8_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR1314296.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2505..3056)
                     /locus_tag="ACL3R8_001435"
     CDS             complement(2505..3056)
                     /locus_tag="ACL3R8_001435"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1314297.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3072..4331)
                     /locus_tag="ACL3R8_001436"
     CDS             complement(3072..4331)
                     /locus_tag="ACL3R8_001436"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR1314298.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGVSIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5486..5644)
                     /locus_tag="ACL3R8_001437"
     CDS             complement(5486..5644)
                     /locus_tag="ACL3R8_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314299.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5654..6964)
                     /gene="obgE"
                     /locus_tag="ACL3R8_001438"
     CDS             complement(5654..6964)
                     /gene="obgE"
                     /locus_tag="ACL3R8_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR1314300.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7028..7162)
                     /locus_tag="ACL3R8_001439"
     CDS             complement(7028..7162)
                     /locus_tag="ACL3R8_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR1314301.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7221..7397)
                     /locus_tag="ACL3R8_001440"
     CDS             complement(7221..7397)
                     /locus_tag="ACL3R8_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR1314302.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7428..8753)
                     /locus_tag="ACL3R8_001441"
     CDS             complement(7428..8753)
                     /locus_tag="ACL3R8_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR1314303.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRSSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8769..9812)
                     /gene="cpoA"
                     /locus_tag="ACL3R8_001442"
     CDS             complement(8769..9812)
                     /gene="cpoA"
                     /locus_tag="ACL3R8_001442"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR1314304.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9927..10256)
                     /locus_tag="ACL3R8_001443"
     CDS             complement(9927..10256)
                     /locus_tag="ACL3R8_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR1314305.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10270..11379)
                     /gene="rpoD"
                     /locus_tag="ACL3R8_001444"
     CDS             complement(10270..11379)
                     /gene="rpoD"
                     /locus_tag="ACL3R8_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR1314306.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11382..13142)
                     /gene="dnaG"
                     /locus_tag="ACL3R8_001445"
     CDS             complement(11382..13142)
                     /gene="dnaG"
                     /locus_tag="ACL3R8_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR1314307.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13232..13990)
                     /locus_tag="ACL3R8_001446"
     CDS             complement(13232..13990)
                     /locus_tag="ACL3R8_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314308.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13987..14853)
                     /locus_tag="ACL3R8_001447"
     CDS             complement(13987..14853)
                     /locus_tag="ACL3R8_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314309.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMDLMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14922..15926)
                     /gene="trpX"
                     /locus_tag="ACL3R8_001448"
     CDS             complement(14922..15926)
                     /gene="trpX"
                     /locus_tag="ACL3R8_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1314310.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16039..16256)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16339..19035)
                     /gene="ppc"
                     /locus_tag="ACL3R8_001449"
     CDS             complement(16339..19035)
                     /gene="ppc"
                     /locus_tag="ACL3R8_001449"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR1314311.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFDSSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19055..20284)
                     /locus_tag="ACL3R8_001450"
     CDS             complement(19055..20284)
                     /locus_tag="ACL3R8_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR1314312.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20440..20742)
                     /locus_tag="ACL3R8_001451"
                     /pseudo
     CDS             complement(20440..20742)
                     /locus_tag="ACL3R8_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21190..21411)
                     /locus_tag="ACL3R8_001452"
     CDS             complement(21190..21411)
                     /locus_tag="ACL3R8_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1314313.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(22091..23302)
                     /locus_tag="ACL3R8_001453"
                     /pseudo
     CDS             complement(22091..23302)
                     /locus_tag="ACL3R8_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428251.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(23304..24548)
                     /locus_tag="ACL3R8_001454"
     CDS             complement(23304..24548)
                     /locus_tag="ACL3R8_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
                     /protein_id="HGR1314314.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(24572..25600)
                     /gene="galE"
                     /locus_tag="ACL3R8_001455"
     CDS             complement(24572..25600)
                     /gene="galE"
                     /locus_tag="ACL3R8_001455"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR1314315.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLVYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            complement(25602..26273)
                     /locus_tag="ACL3R8_001456"
     CDS             complement(25602..26273)
                     /locus_tag="ACL3R8_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314316.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
BASE COUNT         8134 a         5670 c         4280 g         8289 t
ORIGIN      
        1 tttcgcagga agtctaatct aaaaaaggta aatttaagat tggcaatacg aacgttaaac
       61 agaattccat ttctcttttt agaatcaaaa cgacaatatt gtggaatctc tacaggaaca
      121 atagactgcg acactaaaat atcctctctt agttttactt tactaatagt atataggagg
      181 agagccctga atcctagacc ctttgttatg atgcgcttac aaacagagtt ggaaaaaatc
      241 ttaaaagcag aaaaacgcat gatatcagcc cctaacactt gatacaatgc gttttattat
      301 gaaaagatct actggatttt ttatcaaaat aaacttccag tagtcttttc actttttatt
      361 aataagttcc ttcttcacct tggctagtca agataacagg tccatctttc gtaatgacaa
      421 attggtgttc atactgacat gacaatccac cgtcaatggt cttatgcgcc caaccagttt
      481 tcatatctgt atcaatttcc caatcgcctg tattgatcat tggttcaatg gttaagacca
      541 ttccttcacg aagacggagt ccacgacctg caataccata gttaggaacc attggttctt
      601 cgtgcatagt tgggccaaca ccatgaccaa ccaaatcacg cactacaccg taaccacgac
      661 tttcagcgta ttcttgaata gccgcaccga tatcaccgat acgatttcca acaacagctt
      721 gctcaatacc cttgtacata gcttctttgg ttacatccat caagtttttg acttcttcgg
      781 acggtgtacc aacagcataa gcccaacatg agtctgctaa accaccagaa tagctctgag
      841 tgtatttttt catttgttca acattgttga agtttaattt tgagacattt aggtcagatt
      901 tagcaatggg acctcccaaa accatatcaa ctttgagcaa atcaccatct ttcaagatat
      961 aatgacgagg gaaagcgtga gccacttcat cgttaagaga gcaacaggta gcataaggat
     1021 agtccatcat ggcaccgtca accccaatct gaagtggaag gaaattttct tctttacaac
     1081 gacggcggac atattcttca acttcccaca tatctacgcc tggcttaatc aaatcacgta
     1141 agcctatatg aatacttgct agaaaatcac cagccttgtc catagcttcg atttcacgag
     1201 ctgattttaa tgttatcatc ttttctccta gtttctaatt aattttaaca gtcacatttg
     1261 cttttgaaac aatctggtga ccatgataaa tatcgtaatc aattatagct gaccgtctcg
     1321 tatgatgaat aatccgtgcc tgaatgcgca atatatcatc tatctgaaca gcctgcaaaa
     1381 agtagatcag catctgctcg ataatgagat tgcgaccact attaacaact aaatcttggg
     1441 tcatgtgggt cagaatttct gccaatacac cattagccaa aactccattt ttttctagca
     1501 taaagggttc cactgtaatg actacttcat catggtgata agagagcttt tgtccaatct
     1561 gctcagaaaa agttggtaga gccgaaactt gggaacggct catcttctcc atgacatctc
     1621 gtcgcgtcac aacgccaagc aaagtttgat tgcttcgaac aactggtacc atttcaaagt
     1681 cttctgcgat catccgttga ctcacattgg caatatttgt cgataatcca accaaaaata
     1741 gactacgaga cataacctta tcaattgtcg tgcttggtga tttatcacca gcgtctctca
     1801 tggttacaac accaacaacg acctgatgtt gattgataac agggaaacgg ctgctacgat
     1861 tcttacgaac caagtccaaa taatctttaa ctgtatctgt ctctcttaga aaaccatact
     1921 catgactagg gcgataaagt ttctcaactg tcagaatatc agtcttgatt tggacatttg
     1981 acaaggcttt attgatcatg gtcgcgacgg taaaggtatc atgcttactt cttagaacag
     2041 gaatcccttt ttgattggcc agtttaagca catcatcatg aacctgaaat ccccctgtaa
     2101 ccagaactgc attttcattt tccaaggcta gcaactgaat acgggttcgg tctccgacaa
     2161 tcaagagccc cccatcatga aggtaagaca agatattttg ttcagtcatg gcaccaattg
     2221 aaaacttact aaactctctc tctaaacctt cttgcccagc cagaacctca gaagaagtca
     2281 cttctgcaat ttcagcaaac gttaatctct ctatagcaac tttctgggat ttaacacgaa
     2341 ttgttccact tctaggacgg gtctccacaa ttccacggtt ttcagcttct ttaatagccc
     2401 gataggctgt tccatcacta actcctagat gattcgaaat gctacgaaca ctgacccttt
     2461 tacctactgg taattcctcc aaatagctta gaatttcctg atgcttactc attgaactct
     2521 ccttttacat accgaaattc aagataatcc cgcatttttc ttgtgtaacg atcacttccc
     2581 ttaaactgac ggaacaaact aaatccagac ttaagagcaa ctctttggct agctttattt
     2641 tcaaggtggg taatgataaa taattgtttt aagccaaatt cctcaaaaga aagctgacaa
     2701 atttttctaa caacctctgt cataaatcct tgcgaccaag catcttttct caaaaaatag
     2761 ccaagctcag cttctttttt gatttcatct aacttctcaa atttaataga accaatcatt
     2821 tgttgatttt tctggtcaca aattgcccac actcccaaag gggacttcat aaagtaattg
     2881 gccagtgcat attgactttc ttccagactt gcctgcgttg ggaaaataaa ttgaagattt
     2941 tctggatttg aagctatctc gcggaagtcc tgactatcac taaaaaagaa aggacgcaaa
     3001 tacaagcgat ccgtttcaaa aaaagaaaac attgctaatt tggtccaaat attcataaac
     3061 acctctacgg tttaatcctc aacaagtcta atatccgctc ctaaattacg taatttttcg
     3121 ataatatcag aataaccacg taagataaac tcgatattgg taatttcagt tttaccttca
     3181 gccataagcc cagcaatgac tagtgcagcc ccagctctta agtcggtcgc tttaacactg
     3241 gtcccacgta aatcacgtcc acccgtgtac aaaatatgac catttgttgt cgaaatatcc
     3301 gcatccatct ttgctagttc aaaaacatga tttacacgtt tttcgtaaat cgtatcgaca
     3361 attgtaccac gaccattcgc tcttagtaaa agaggggtaa gcggttgttg caaatcagtt
     3421 gcaaagcctg ggtaaggagc tgtcttaata ttgattgctt tcaaattaga ctgttcctcg
     3481 acaaaaatgc tgtcttcaga tacagtcatt ctcactccca tttcttccaa cttagcaata
     3541 aacccttcca ggtgttcgta aagaacatta tttatacgaa ttcctttacc aactgcagca
     3601 gctaaagata tatatgttcc agcttcaatg cggtctggaa tcacctgatg acgtgtccca
     3661 tgtaatcttt caacaccatc aataatgatg atattagttc ctgccccacg gatatgggca
     3721 cccatattat tcaagagagt agctacatca ataatctcag gttcacgagc tgcattttca
     3781 ataatagtac gaccatttgc tttaaccgca gcaatcatcg tattaatcgt tgctcccaca
     3841 ctaaccgtat ccatgtaaat acttacacca tgaagtcctg tatctttagc agataacttc
     3901 atgttatctc cctcgtagct agcagtggca cccatagctt caaacgcctt aaggtgtaag
     3961 tcaatcggac gaggaccaag atcacatcct cccggtagac caactgtcgc ttcaccaaaa
     4021 cggcctaaga ggctcccata aaaatagtaa gatgcacgaa gactgttaat tttaccataa
     4081 ggcattggaa tattttgaac acctcttgga tcaatctcca agacatcgtc ataacgctta
     4141 acagtagctc ccatcaattc catgatttcg acaagactgg ctacatccga aatatctgga
     4201 acacaatcca aagtcaccac atcatcagcc aatataatag ctggaattaa ggccacaaca
     4261 ctatttttag caccactaat agtaatttca ccttgcagtg gtaatccacc attgataaca
     4321 atttttctca ttctaagttt tcaatactct ttcaagattt ctaataaggt cttcaaaata
     4381 aagtatatca taaatttatc cttttttcca tccttttcaa ttttattggc taaatcagag
     4441 ttgacgagtt agtaactgaa ttactaatac tcaataaaaa tcaaagatca aactaggaaa
     4501 ctagccgcag gttgctcaaa acactgtttt gagattgtag atggaactga cgtagtcagt
     4561 atcctacaca tacggcaagg cgatattgac gtgatttgaa gagattttcg aagagtataa
     4621 tctttctcga atcgctattg cccctttttt atcccctaaa actgagtagg agctaagact
     4681 agatctctta tctaagtatc ggaatacggc tgttcaacta aattttagca agaacttctc
     4741 ccccttctct cagttcacag aagcgtttta tacataccgt cctatcagac aatctatttt
     4801 aaagataacc gtgactcagg atcacttcta tctgtcgttt tctctttata gtgatagacc
     4861 tcacgggata agtcgtacat ctttcctcgt gtatacaaga tatgagggcg ttaaaaggtt
     4921 acagtgaaaa tagaaaatct tagtacgaat tcaattactc tcgtgattta cgcatatagg
     4981 ttacgactac ctttttggac tttagaattt gaggccctct tatccgctat atacgcctta
     5041 ttatcacgtt cctgttcgta gagccacgat ttcgctatcc cttcttctga caattcttat
     5101 ttccagcgtc agacttaaaa cggtctatcc ccagaccatt ttaatctgct acctcacgat
     5161 agtcaggctt gggaatcgct atttgactcg ccgagaactt tgacatcaga tatactataa
     5221 caaattgaaa taagaatcaa acaatttaat tttgaaattc aaatcaattt ataacaatat
     5281 agttgattga aactagaata gtacatctct gcttctaaaa cattgttaga aatcgatttt
     5341 actgtcctga tcgatttgtc ctgttctcat ttcattttac tatattttag aagatatgct
     5401 gtgctattcc agattcagtt tgctatacat gcctgtcgta ccacaaaatc ccgtgtctga
     5461 tgaggcacgg gattttttag cttctttact gagatggatt ttccttttta gttcgtgcca
     5521 atctcaaggc acgatttgga ttgagacgat taaatagttc ttccaatttc ttttcattcc
     5581 aaacgtctgc ggcggaaaca aaattaccat ccgcatctcg gaaagatatc ggtttatctc
     5641 ccataccagt ctcctagtct acaaattcaa actcaaattt accaatgcgg accaaatccc
     5701 catctttagc tccacgcgca cgaagggctt catcaacccc cataccacga agctgacggg
     5761 caaatttcat gacagattca tcacgatcaa agttggtcat attaaagagt ttcatgagtt
     5821 tttcaccaga aagtacccat gtcgcatcgt catcacgact aatttcaaag gctttttctt
     5881 cttcgtcaaa tccatagtaa gcttcttctt ccatatcgga ctcgtcgtag agcaaaaatt
     5941 ctggtgtctt gtctaacaat tcagctgtag catctaaaag tgttgccaga ccttgcttgg
     6001 tcaatccaga aattgggaag atagctggta actcttcaaa ttcatcataa ttttcagcca
     6061 attttttctt aaagtcttca agattttcct gactctcagg catgtccatc ttattagcta
     6121 caataatctg tggacgctcc atgaggcgaa gattgtaaga ctccagctct ttattgatag
     6181 ctaggtagtc ctcatatgga tcacggcctt cgctagctga catatcaatg atgtgaagga
     6241 taacacgtgt acgctcgatg tgacggagga actgagttcc caaaccaaca ccttgactag
     6301 ccccttcaat caaacctggc aagtcggcta ctgcaaagga ttcacctgat tgggtgcgaa
     6361 ccatacctaa atttggtaca atagtggtaa agtggtaggc accaatttta ggcttagctg
     6421 aggtaataac acttaaaagt gttgacttcc ctacagatgg gaatcctact aaaccgacat
     6481 ctgccaagat ttttagttcc aattgtaact cacgttcctg acctggttct ccattttcag
     6541 agatttccgg tgcaggattt tttggtgtcg cgaaacgaat atttccacgt ccaccacgac
     6601 caccgtgggc aacgataaat tcttgcccat gttcaatcaa atctgttaaa accttgccag
     6661 tctccgcatc acgaacagtc gtaccttgtg gtactcgaac tctaaggtcc tcagcaccac
     6721 gaccatgcat ccctttggtc atcccttttt caccagaatc agccttgaaa tgacgattgt
     6781 agcggaaatc catcaaggta cgtagtcctt cgtctacaac gaagaccaca ttgcctccac
     6841 gaccaccatc accaccccaa gggcctccat tagggacata tttttcacga cgaaaggcaa
     6901 ccataccatc gccaccatta ccagccttga ccttaatctt agctgtatct aaaaacatac
     6961 tcattatttc ttctcacttt aaaaaagggc tgggaaatcc cagtcactaa attttcttga
     7021 atctatttta tagattactg agggcaccaa ttgcagttgc aaaaattccc aataaacttg
     7081 ctactagcat gataatcacg ataaacaagg ttattttctc aaacatagtt tttttacgat
     7141 ttccattatc tccaaatgcc atttttctct ccttcgttac attctatttt ctattatctt
     7201 agcatgaatt gagctagttt tcaatagtca gttgctactg gtgcgataat ccataaaata
     7261 atgtaagcta caattccagc tccgtaacag caagtaagaa caccccaaat gacttgaacg
     7321 atagtcggat ccatatccag ataatgggcc accccagcac aaacacccgc aatcttttta
     7381 tcacgaccgc ttctcattaa ttgttttttt catagctgtt cctctttcta ttcttcatgg
     7441 tctttccaat agtctctcat actgatcaac tgtgtttttg aagccttcaa catgcgtcta
     7501 gatcctttta caggtacagc aaccacctgt tgctgaagat acaaaactgt cttaaagata
     7561 cgctgactga ccgtatcatc tttagccaaa tctttctgga agttatttga aataatggca
     7621 tccagataaa actcatgcac tcgtttccca aagttctcag ctgaaatctc atacaatttc
     7681 tctgataagg tatgctcgtt catgtctggt gttgcaatca gggcttccaa aatagcacca
     7741 gccaaatcat gttctccata gtacaaggtt ccaaacattt tatcactgat gaggttgttc
     7801 aaataaggat ttccgtgagc aatgacaggt gttccactgg ctaagctttc caagtaggtc
     7861 aaaccttgcg tttcgcttgt cgatgccgaa atgaagaaat ccgccgcttt atagtaaaga
     7921 gccgtctcac taggagcaat catccctgta aagatgactg agtcttgaat ctctaggttc
     7981 tgggcttgct ctttgaggtc attcagataa gggccatccc cagctactac cagtttaacc
     8041 ttgtcttcct ctttcagaac atcagcaaag gctgctaaaa ctgcttgaat atttttttca
     8101 taggagattc tcgaaagact aagcaacgtc ttttcaccat cttgaatccc tagtttacta
     8161 cgcagttctt tcaaattttc ctgcttgatt tccggacgct caaacttggc taattcaatc
     8221 ccagtaggaa tgacccgttt ttcaaccttg accttataat cagatagcaa gtcacggaca
     8281 atctcactag ggcaaataac cccatccaca tcatgcagga aacctctaac cagatacttg
     8341 accatactcg accggatcaa catcccctta gcaatataat ggacatagtc ttcatactgg
     8401 gtgtgatagg tatggatgac tggaattttc aattcacgcg caatccaaat ccccaacagg
     8461 ccaagagaaa attctgtctg agtatggata atatctagct gatactgttt agcaatttca
     8521 agtgccttgc taaaacctcg gtaggcaaag cgacgatcct taaaagcaaa gaaaggaaca
     8581 cttggaatgc ggataatttg ccaatcttcg tagcgattga catccttatc tgtcgtcgta
     8641 aagataaaaa cagcatgtcc ctgcttttca agttctgttt tcaaggttcg aatactggtc
     8701 gcaacaccag aaacctgagg aaaataggta tctgtaaata aaccaattcg catagattac
     8761 ctcacttttt actttctccc taaagcggct tgtttctcat aaaagtccaa ccagatttgt
     8821 aacagatgct cttcagaata ctctctggaa atattcttgg ccttttcttt gagatctttt
     8881 aagacagcag gatttgcttg atattccaaa atagcctctt tcatctcttc tctacccgct
     8941 gtcgcccgat aatttccctc caaaatcacc ttatagagat ctaaatcacg caacataata
     9001 ggagcctcac aactcgcagc ttctaaaata gtcataggaa agagctcatt gtaactaggc
     9061 aacaagaaaa gatccgctag agcatacaat tcgcgcatcc gctctggcga tacaatgcct
     9121 ggaaaaatca aatttttagg gggattttcc ataattttct tatagtgttc ataaccatct
     9181 gtcataccac caaaagagaa gccaccagcc cagataaagg taatctgagg caattcctca
     9241 gccagacgga taaagtcatc aatcccttta cgtttctgaa cttgcccagc acctactacg
     9301 ataaactgat tgtcactaag accaagatct gtgcgcagtc tgactacctc ttcttgtggt
     9361 agaggatgcc atttttcctt gttgacaaag ttaggaatat aggtcacttt ttcacgtgga
     9421 ataccagctg ctaccaaatc ctcaataaac ataggattga ccacaaccaa gtgctccatc
     9481 cggttgtaaa aagaaaatac atagcgtttc acaattccct ttaagaaaaa tggaattttc
     9541 aaacttcctt caagtgtagc tggcaagaaa tgcacatagc caatctttct ccctgagcgt
     9601 ttcttttgga aggttgataa ataataggga aaatcaatcg tatgaaagtg agtcacatct
     9661 gcctcgattg gaagattttc tgtaacaatc aattggtcct tggcagcacg gtgaagaaga
     9721 cgaactaatt cacggtaagc acctgaaact ccctgtcctg ctactttctc acttgaactc
     9781 aacatattga tgcgtaattt ctttttctcc ataactacta ttatatcatt ttctttgaat
     9841 aaaatcagca aaagaaagga gagactagag gaaaagaggg gaaatttcct cgcttttcca
     9901 acagtctctc acatgctttt atatgtttac ttaatgccta gggcaatgcg ggcatagcga
     9961 ctcatttttt caactgtcca ggctggatac cagactaatt taacctcagt atccgttact
    10021 tctggaacct ctatcatagc atcataaatc tggtctgtca aaaggtctgc taagggacaa
    10081 cccatagttg tcaaagtcat gtcaatctct gtttgccctg tgtcaccgtc aaaacgaatc
    10141 tcatagatca aaccaagatt gacaatatcg attcccaact cagggtcgat gacttcttcc
    10201 aaggctgtta aaatccgtgt tttgatgttt tcaatttgct cttctgtata agccatattt
    10261 tcctcactct tagtcttcaa taaaatcacg aagcggtttg ctgcggcttg gttggcgtag
    10321 ttttctcaaa gcctttgctt caatctgacg gatacgctca cgagttacgt taaagacttt
    10381 ccccacatct tcaagtgtgc gcatttttcc atcatctagt ccaaaacgta gacgcagaac
    10441 attttcttca cggtctgtaa gagtatctaa gatttcatcc aattgctcac gcaagacgat
    10501 acgagtcgta taatccactg gattttcaat tacttcatct tcgataaagt ctccaaggtg
    10561 gctatcgtcc tcttcaccga taggagtttc aagagatact ggttcttggg caatcttcaa
    10621 gatttcacga accttatcag gtgtcatatc cattcgttca gcaatctgtt ctggtgtcgg
    10681 atcttgcccc aattcttgaa ggagattccg ctgttcacga accaatttat tgatagtttc
    10741 aaccatgtga actgggatac ggatggtacg agcttgatcc gcaatagcac gagtgatagc
    10801 ctgacgaatc caccaagttg cataagttga aaacttgaac cctttagaat agtcaaactt
    10861 gtcaaccgcc ttcatcaagc ccatatttcc ttcttgaatc aagtcaagga actgcatgcc
    10921 acgaccgaca tagcgtttgg caatagaaac aaccaaacga agattggctt ccgcaagacg
    10981 ttgtttggct tcgatatcgc cagcttcaac agccagtgcc aactctttct cctcttcatt
    11041 ggtcaagaga ggaacgaccc ctatttcttt caagtacata cggacagggt cattgacctt
    11101 agcagaagtt gacccaatca agtcctcatc gctgagttct ggttcttctt cattgctaag
    11161 aacacgcgca cttggatttc cttcgttatc tgtgatagaa atgcctgcat cctgaatccg
    11221 ttgcaagaga tcttcaatcc catcagcgtc caaggtaaaa ggaataacca gacttgcatt
    11281 gatttcatca tctgttgctg tccctttttg cttatgatta cggataaatt ctgctacctg
    11341 tacgtcaaat gttgttactt ctttttgttt tgttgccatt attactccat tcttctcttt
    11401 tgggaaatta aacgttccaa ttcttctagg gctgtatctg tatctcctac atggctagct
    11461 tcctgcacct tctttttgat tctcatattg tcctgattca agagagcctt gtttcgagtc
    11521 atctctactt cactaagttc ctgcggcgat atctcagcag gcaaatcctg agctaaaact
    11581 tggtaccaag ctctttcaac ttcctctgtc tgctctgcta aaacttctgg aggaagattt
    11641 ccatactggc caagcaagtc atataagacc tgaaattcag gtgtagcaaa tgcaaagtct
    11701 tctcgcaaac ggtaatcgtt caaaacaaga ggggattcca tcatccgata gagtagatgg
    11761 gcttctgccc tcataatagc cgataactgc ttggtgatag gcatggtgat tggcgtcggt
    11821 ctggaaattc cttccatgcg attctgcctt tgcacctgac gactctcatt aacaatctgc
    11881 tcaatctggg tataatcaaa ggacgccaga ctgtcagcta aaatatgaat atagctgttt
    11941 tgagcagcga tggacttttc ttgaacaatc aagggagcta ttttttcaat aaactcaatc
    12001 tgagcctgca gattttcact gttttcaggt ttgtactgat gaatgtagaa ctcaatcgga
    12061 ctaatacgag tttttgttaa tagataggcc aagtcttctg gaccattttt ttgtagatac
    12121 tcatcaggat ccaagttatc aggcatgcta acgatttgca caggcatatc accaatttca
    12181 tccaatgctt tcaatatcgc ggcttgccca gccttatctc catcgtaaac aagaaccaat
    12241 ttcttggtta accttttcag atgctcaaca tgctctcgac tcaaggccgt tcccatcgac
    12301 gccacagcat tttcgattcc agcccgatag gctgcaataa catccatgaa tccttccatc
    12361 aggtaaatct cactagcttt tccagaagat ctttttgccc tatccatatg atataattcg
    12421 taacttttgt taaaaattgc agtcgatcgg ctgtttttat acttagaagt ttgtgaatcc
    12481 gttttttgcc agatacgacc tgagaaggca atgacctttc cttggtcatt tgtcagggga
    12541 aacataatgc gattgtgaaa ggtgtctaca aattgattgg catccgagag ataaaacagg
    12601 cctgaatcca gtaaatcctc ttcacgatac tgatcagaca aacgttgata gagatagttt
    12661 cgttctggag gtgctaaacc aatccaaaaa tgtttaagca cttcatctgt caaaccccgc
    12721 tgataaaggt aatttctggc ctcttctccc atagtcgttg tcatgagaat agcatggtaa
    12781 aatttggctg catcttcgtg catatcataa agagcttggt gaggcgaggc tggcttctgt
    12841 tcactataaa gcggtttttc aacctcaatc ccgacacgct gacctaagat ttggacagcc
    12901 tccataaagg taaccccttg gtactcctcg atgaatttaa agacatcacc tgagcgacca
    12961 caaccaaaac agtggtaaaa ctgcttgtcc tctacaacgt tgaaagaagg tgttttttca
    13021 ccatgaaaag gacagagccc tagatagttc cgtcctgcct tttgtaaaga aatcacatct
    13081 cctatgactt ccacaatgtt ggcattgttt ttgatttctt caatgacttg tttgtcaacc
    13141 atacacaata cctccatgtt atcatagttt actttatata gtatacttta tttcagaaaa
    13201 aaagtaaacc atttcactca ttttccctac tttattcaaa gagttgataa taatcagaga
    13261 ttttcatttt tgctttttct tcttggttta aatcttggat aatccgtcct tctttcatga
    13321 caatcaagcg attgccgtat ttgagagcat cttccatatg atgagtaatc ataagggctg
    13381 ttagctgatc tttcttaaca aattcatctg tcaattccat caaagcaaca ctagtctttg
    13441 gatccagggc agcagtatgc tcatctaaca ggagtaattc aggtcgcttc aaggttgcca
    13501 tcaagagact caaagcctgt ctttgtccac ctgataagaa ctcaatcggt gtattcaagt
    13561 gtttctcaag accatttcct actttttcaa tggttgcctg aaattcatcc ttatagctag
    13621 tcaagcgtct tggtaacaat ccacgctttt caccacgaaa cttggcgatt aaaagatttt
    13681 cagcgaccgt catacgggga gctgtcccca tctttggatc ttggaagaca cgagacaggt
    13741 acttggcacg cttctcgggt gaaaacttag tgagatcttc acctaaaata cggatagttc
    13801 cactagttag tgataaggtc cctgctatag tgttaaagag agttgatttt ccagcaccat
    13861 ttccgcccaa aatcgtgata aagtcccgtt caaaaatttc taaggaaaca tcatttaaaa
    13921 taatcttttc ttcatcaaag ccatttttaa cgattttggt tgcatttttt aattctacaa
    13981 ttgctgtcat ttgcttaact tggctccttt caagattgtt tgcttaaatg ttggaatcat
    14041 gaggcagact gctaaaatca aagcactgta taaacgaagg taacttgtat taaagccaag
    14101 tgcgataact gcccacacta aaaattgata agcgatagaa cctacaacga tagtaaccaa
    14161 acgctctgcc aagctcaaac tcttgaaaat aacttctcca ataatcaaac ttgcaagccc
    14221 cacaacgata accccgatcc ctcgagacac atcggcatag ccttcttgct gagcaatgag
    14281 ggcacctgca agggcaatca caccatttga taagaccaag cccatgagat ccatgcgtcc
    14341 agtatgaatc ccgaaacttc tagccatatc aggattatcc cctgtagcaa tataggcttg
    14401 tccgagttta gtgtccaaga aaaagagcat gagagcaata acaatgctca caaagatgag
    14461 acctgtcaag agttgattca aatccgaatc aaaaggcaaa acatcctgaa tttgcttggt
    14521 tccaagcagg cctaaatttg cacgtcccat aatcaagagc atgattgagt gacaagaagt
    14581 catcaccaaa atccctgaga gcaaggttgg gatcttccct tttgtataaa gaaggcctgc
    14641 tgccattcca gccaaacaac ctgctcctac agcaacaagt gtcgctaaaa atggattcac
    14701 gcctttggtt atcaaagtga cagcaacagc tcccccaaga gggaaggaac cttctgtcgt
    14761 catatctgga aagtttaaaa tcctaaatgt cataaagatt cccagaccta gaatagccca
    14821 gacaaatcct tgagaaataa tggaaacaat catattttat ttaatccttt ctatattcat
    14881 ctttttaaaa aatgggaaga gtctcctcct ccctacctta tttattcgat gacttgtcct
    14941 gcttctttga gaacagactc aggaatagta atacctagtt cttgtgctat ttttttattg
    15001 ataactgact taccagttga aaagacattg actggggtat cggctggttt tgcacctttc
    15061 aagacttgca caatcatttt acctgttgcc acaccaaggt catgttggtc aattacaact
    15121 gatgccaaac cacctacttc taccatagct gtcgcactgg gataaattgg tttcttagaa
    15181 ctttgattgc tagagacaac cgttggaaat cctgatgcaa tggtgttatc aattggaacc
    15241 caaatagcat ctaccttgct agtcataaca gtgacagttg aggcaatttc atttgttgaa
    15301 ggaactgcaa atgtttccac tgtcagacct gctttttcag cataagcctt aaattcttcg
    15361 acctgtgttt ttgaattgtc ttcgctactt gagtaaagag ctccgattgt tttcacattc
    15421 ggtgtcagag ccttgatgag ttcaacttgt tgttgagctg gattgtggtc agatacccct
    15481 gtaacgttgc cacctggttt tttcaaatct ttaaccaagt tagcaccaat tgggtctgta
    15541 atagcggcca tgataaccgg taggtctttt gttgcactag ccaacccttg ggctgctggt
    15601 gttgcgatac caaccacaag gtcattccca tttgcaacca attgtttact cattgtcgca
    15661 accttacttt ggtcaccttc tgagttcata aaatcaattt taacttgatc atctttatat
    15721 ccttcttctg caagtccatc ttggatccct ttataaatca aatcaaggga tggatggctc
    15781 acaaattgaa gcacaccaat cttggttatt ttcttctcat ccttattatt ctgaacttct
    15841 gatttattca ttgaagaata aatcaagctt cctgctacta agactgctaa tgcagcaata
    15901 attccaatta aacgtttatt tttcattctg tttctccttt ttatttcctt taacatattt
    15961 cacttatcta aacaagcgac gccattgttt tctttccata ctaacctcca tcaaaaaaat
    16021 cctcacacaa aaaacttgtg tgaggacgtc gatgcgcggt accacctcaa ttatagggaa
    16081 tttccctatc gctcagtctc gcaataacga gatgcactgt aaggtgtgct taccgaattt
    16141 ttataatttc aaattctaaa tagcattcag cccaattttc atcattgcca cttatctgtt
    16201 ttcagctacc acagactctc taaaaagttt gtatgattac ttttctgaat ggttaaatta
    16261 tatcattttt aaactacttg tcaatagtct attagaattt ttttgatatt cacttttagc
    16321 attcactctt gaaaattatc aacctgaatt acgcaatcct gtcgcaattc cgttgatggt
    16381 gatatgaatc aatcgttctt gatcactgga caattctcca cgacgttggc gtttaatcaa
    16441 ctctaactga atatagttga gaatattaaa gtaaggcata cggtaatcca gactagcttt
    16501 tagatatgga ttgtcagcta agagttcgtc atgtccttca atagccaaga taacgttctt
    16561 agtaacttgc cattcattta aaatagtctc atagatggcc ttaacttgct cgtcttcaca
    16621 aagtttagca tattcaaaag caatattcat atttgatttt gacaaaacca tatcaacatt
    16681 tgaaagaagc gattggaaga aaggccaatt ttggtacata tctcgtaaga tagcaatatt
    16741 ctctggattt ttattgataa attccttgaa gcttgaacca accccgtacc atccagggaa
    16801 cataacacga ctctgtgacc atgagaatac ccaagggatg gcacgcaatc caccgatttc
    16861 agtaatagtc ttacgagcgg ctggacgaga accaatatta aaacttgaaa tagccttgat
    16921 tggacttgaa tcgaagaaat aatcatagaa atgctcatta ccaaagacca aatcacggta
    16981 gatatcgtaa ctacggtcca ctacttgatc cataatggct tcataacgat ttggggtatt
    17041 ggtatcgctc ttcttctgag taatcatacg gttaatagct gccgatacta gcatttcaag
    17101 gttatagtaa gcggcgtctt tgttaccgta tttattccca attacttcac cctgctccgt
    17161 caagcggata cgatccttga tagacttgag cggttgagat gtaatggctt cataggttgg
    17221 cccaccacca cgaccgacag taccaccacg accatggaag aaggtaacct taacgccaaa
    17281 ttcatctcca atagcagtca attgttgttg agccttgtag agggtccaac atgatgacaa
    17341 gtaaccgcca tctttattac tgtcagagta gccaagcatg atttcttggt agttatttcg
    17401 tgagtcaatc cattttttgg caaggctaag agaaagatat tttctcattg tttcctctga
    17461 atgatccaag tcttcaattg tttcaaaaag gggaacaatc tgaacacgcg ccctttccgt
    17521 atccaccagt cctacttctt ttaacagaat agctaattct agcatatcag aaaggctggt
    17581 tgcatgtgaa atgatggtct gacggatgac atcatctccc aacttatctt tcaaaacacg
    17641 agccgtctta aaaatagcta attcttttgc taataattct gatttttctg cgtgagtcgc
    17701 agaaagaatt cggggatctt cttctaattc tttcaagaga aggtcacact tttcttcttc
    17761 gctcaactcg ctataacgag aatgaattcc tgctgatttc aagagttctg ccacacaggc
    17821 ttcatagacg ctagagtctt gtcgcatatc aattgacgct aagtaaaaac caaatatctc
    17881 tactgcctgc aataattcca caaaatcacc tgaaatcaag gactcaccct tattttctag
    17941 tagagaatct cgaatggcaa tcaaatcctt gtagaaatca ttggcggttt cataacgagt
    18001 cccaacttct tcatcctcaa tcagataggt tttagttgcc tgaatttttg attgaatatc
    18061 aaacaaggca cgacggtaaa gctctttttc gcggtaaata gagttatcct tggattgacg
    18121 agccatttct ctgacttgct tgctgacgtt gacaatgcta gttgaaagag aaaattcacg
    18181 ataaagttgg taaatctttt tatcatagta gttcatgatg acttcacact gagtgagtgc
    18241 agactgcttc aaggtctttg ctgtaacaaa tggatttcca tcacggtcac cacctatcca
    18301 catacccatg gtgattggtt tagcctgttt taaattcaga ccatgcgctt gcgctaagcg
    18361 cttatactcc gtcgtcaaat gagggacagc tttcaaaaag gagctgttgt aatattccat
    18421 agcattcgtg atttcgttag tcacttttaa ttttttctca cgaatcatgt ctgtctgcat
    18481 gataatttcg atgtaacgac gcaaatcatt gtgccattta tctttattga ttaaccccaa
    18541 cttaacatca cggtatttac gcaaaagact atgaatatga tttgttaaat ccaacatact
    18601 tttgcgttgc acttgtgttg gatgggctgt caaaacaggg acaacattca agtgttctag
    18661 gatctcaacg gcattttcct tttctgctac caatttaatc gttgtagata atttacctaa
    18721 atagtcctga tcaatattat tttgatgatt gatttcataa gctaaatcca catcctctga
    18781 aatattaatc aaaagaggta agatagagaa atagcgtgaa atatagacca tttcatcatt
    18841 tgataagcta gtcactagac ggtttagacc ttgataatct tcctgcgttg ataattcttt
    18901 caactgtatt attttttcaa aggtctctgg ggcaagcata tttttagtaa tatcttccag
    18961 taattctgtt agaatcaaga cttcttcttt cacaacactt ttattactat aattttctaa
    19021 tttttgaaga gacataaact atcctttctt tatcctactt caacagaagg ttcattggtt
    19081 gattttccaa ttctcggtac aacttagcgc gtttttcact ggcatcaata tttaagacaa
    19141 aggctactgc cactgataag actagaagac tatttccacc ctgggataag aaggggaaag
    19201 tcactcctgt agatggaatc aagcccgaaa tccctccgat attgacaaat acctgaacca
    19261 acatcatccc tccgacaccg agtgcaacca tggcattgaa aggattctcc gctcggatac
    19321 cgaccaagat aatccgcaaa atcatgaaaa acaagagagc taaaataaga ctggcaccaa
    19381 caaagccaaa ttcttcaatc acgatagaaa agacaaagtc tgtatgagct tctggcaaat
    19441 aacctcgttt ttcaatcgag tttccaagac ctagaccaaa ccaaccgcca ttgaccatgg
    19501 caaaataaga attagctaac tggtgacctg catcagcacg atcggcaaaa ggattaaaaa
    19561 aggcactaaa gcgcttggct acatagccaa atactggaat ttttgaaaag gtctcaacac
    19621 cgattaggct gatagtggtc aagacaaaga cagaagtggc agatacgagc gccagaatgg
    19681 ttgaaaacca gcgataagcg attccactaa ctgtatacat aatcaaggaa accaagacta
    19741 aaatagtcgc atttcctaaa tcagggaaaa ttcccaaact tccaatcaga actaggagaa
    19801 cgaatcgcca atcattaaaa gcacggggaa gccattgatt ttgagtcaaa acttgaaaat
    19861 cataagtagc tatttcttct tgctgtttgg agaatcggtg agctaaatac caaataataa
    19921 tgatttttaa gtactcagct ggctgaatag ttactcctgc aaccgaaatc caaccgtatg
    19981 ccccgtttac ggaaatacca ataaaacgag ccaagaacaa taaaagcatt tctattaata
    20041 taactaaaat gattagtcgc tcatttctca aaaaatctag tctcaattta taaattaagg
    20101 caatcagtat caaactaaca atccaaaaga ttccttggtt tcgaaccaac tgcaaggcac
    20161 tcttgccttc ttcaattaaa atagcactgg tggtcgaata gaccacaatc aagcccaaaa
    20221 tagataaaag caagtaggga atcaagatgg aataatttaa taagtgcctc ttactaatct
    20281 tcatagcatc accactctac taggatacag ataaatctgt tccaaattcc gttttatttt
    20341 ctagttttga ttgctattat accatttttt cagaaagaaa aaaactctta ccttacaatc
    20401 cttcgaattt tactgttttt acagaattaa ggcagaattt gaaatcgtaa aaccattttg
    20461 aataagagtt gcttcaaccc attgactccg acggattaag ttgctttcgt gaatgccaaa
    20521 atcagccgca atttgttcat aagtgctcta ttctcgcatg tattgaatag ttaccataag
    20581 gagatcgtct aggattaatt tgctttttcg tccacctttt gcgcgtttac gttgataagc
    20641 tgtttttaac acagctaaca tctcttcaaa agtcgtgcgc tgaacaccta caaggatctt
    20701 gaaacggcta tcgcttaatt gtttacttgc ttcatcatcc atagttttat tgtattgtat
    20761 ttttgtttcg caggaagtct attattcctt tcgttccaag gtttttacgc tttttcaagc
    20821 aatcctacac actccacgtg atgcgtctgt ggaactcaaa aggttcgggg aaccttttga
    20881 ggattaattg cgtttctcta acaaactcac acattcaacg tggcatgact gatgaagtca
    20941 tcataagaat ttcacttgct gctctttctc ggtggcagcc tgaacggtca gaagtatcat
    21001 tgtatatcat ttgtatcatg gcatataaag tatcgctcta ttttattgat ggttttaata
    21061 tcgctcttat catggcgaac cattcaaatc tgctccacaa atgaggaaag taccattttg
    21121 gactattcaa ttgtcaaaga acaaataaaa aaaatcttcg cattttcaca ctctatgaaa
    21181 ttgaggagat tattttctaa agcgaatttt atcaggaaaa tccgtcaatc ccaataggta
    21241 gtctgtactg acatcgtaaa agtttgagag agttaccaat atatctgctg ttaacgtatg
    21301 ctcaccccgt tcaattttag cataagctga gtctgtaaac gaaagtattt tagctatttg
    21361 tttttgggtc aaatcgtgat cttccctcaa atctctcaaa cgtctgtaca tctagctttc
    21421 tcctgagaaa agtataatat ataaaactaa gaaatcattc aaagtgtcca aactggacat
    21481 tttgaactaa aattaattta ttaaacatat ctcataagca tatctattat aggtaagaca
    21541 atattaagaa agacggtcaa aatctattaa ccgtctaaag atgttataag ctattaaaaa
    21601 atcagcagta atccggtaac aaaagtcaca taattttgtt aaggaaggga ttaatgatgt
    21661 ccagattact actaaccagc aaattgaaaa atggtcaaca tgatatttct aatgtgaatc
    21721 tcttactttc agaacctaaa agttgaataa tagccacccc ctacttatca ataaaatttt
    21781 ccgttgcatt aacagatgta tatagaccac tccatggatt tcaaagcaat taactagact
    21841 ttatttgtca ataaccacaa aattagatta gaaaaatcat taaaaattaa ttggagtcct
    21901 ttgtgatgct ttttcaataa aagtaatact tctcaatatt ttaactgaac taaagaaata
    21961 gcataatggt atcttgattg tattcttcta aaaaggattg cccttcacat tcaactgtga
    22021 ttgattaaat tccaaaaata tattccaaag gcgctctaaa ttctctatat cagctatttt
    22081 ttatcatcta tcaacttcta tcatacctct tcaatagcgt gctaaatatt agcgataata
    22141 tcgtaataga tacaccaata ataaaaaaat taaaagtatt gttaggattt aaaactactg
    22201 agaaaaaaac agtacctagt ggcataaaaa gaatagctac cgtaaagatg attccaaata
    22261 ctctgccaag aaactcatta tctacgtctc tttgaacaat agagaaaaat tggatattaa
    22321 aaatggaaag aaatagacta aataatgctg gagtaaaggc taaaataatg acgttgcgga
    22381 acatataata gatcggcgct gttagcatta acatcaaacc tgaatatgct aaaaagagca
    22441 ttaaacgttt gcttgacaag gatttattga taaatccact taatatcgca ccaataaagc
    22501 caccaatcgc ttcggctgtt aaaaaggttc catatagccc acttgaaata cttccaaaca
    22561 tttgattact gtatggcagc aacaaattat aggctgctag gaaaaagtta acaagtgctg
    22621 aaagggcaat tatagtgaga atttgtttat gactatatac atacgtaaat cctattttta
    22681 aatcatcaaa gattcctctt atcgtcatat tctcttttgt atccacctcc tcatttacag
    22741 gagtaatgaa gaaaattagt gaggcagcaa ttaaaaacga taatccatct agtaataaca
    22801 caccatgtat tccaagtaac ttatataaga aaattgcaat cataggaatt gttactttaa
    22861 tcacagtact tgttgtttct agcaatgaat taagttatga tatactgtcc ttttttacaa
    22921 tttctttcgt aaaagctttg tatgatggcc ctgaaaaagc actcataaaa gccaaaatga
    22981 catttgttat gactatcgca taaaccaacc atttttcttg ggatataaat gaaagagtta
    23041 tgcaagcaat accacataag atatttgtag taataataat ttttttccgc ttgaaactat
    23101 ctgcaataac tccaccaaat aaattaaata gaacacctat catactttct aatgattgat
    23161 aaattgcaac cactgataga gatgttggat taagaccagc aagaaaggta ttattggcga
    23221 aatcaaacat gatatctccg attcgagata tcatcctact agctacaatg gatagaatat
    23281 tgtgatgttc ttctctaatc attttattct cccgaatcag taatcacata tttaaacttt
    23341 tgtgatatgt gcttaagttc atctaacctt ttctcaaatt cacaactatt tttgcaatta
    23401 aattggacca acattgaatt ttcgactaca ttttcagata ctttatagta agtatttggt
    23461 ttaataaata tgtacacttt ttttgcccaa gccaattctt tttcatcagg tacctcgata
    23521 accttacctt gctttctata taaagcaaac gttgctgaga tattagcagg tctagaaatc
    23581 actttagaaa aatttatttt tttcaatcct tgtgaattag tcaaaatatc ccaatattct
    23641 ttaattacat caactccatg actatcctca attaactggg gaatatctcc ccctccaaat
    23701 ctttttccaa cttcacaaaa gactatttta ccagttgata attcaaggaa ccattcaaaa
    23761 tgaaaagggg ttatttcaga attgatagaa aaaacattca aaactttgcg acattcttcc
    23821 aatgcttttt ctatgtattc aattttttca ctatcattat ataacgaact agtccttaca
    23881 agataatatc cactagaact taaggtattg aacaatagtt cctcatattc gtgaacataa
    23941 aatcgcttaa tctcacttcc aattgaataa ccatcacatg ttatcatgtt atcgatatca
    24001 atgtattcct ctataatata gtttttttca aaatacactg aatcaatttt ctcgttaggg
    24061 taaacttttt ttattccatt acttcctgct tcatttctag gttttaaaat tgcagcagaa
    24121 gatttacaat tattccaaaa aacacgtaaa tcattttctg attctaaaag cctaaaatac
    24181 ggttgattta ctactccaac taaaaatgaa cgcatgaagt atttgtcttt aaataataaa
    24241 ttagacacag agtgagtatt tttttctaca aaatgatcat tcaaaaaacc tactatatcc
    24301 atgtcttcct cactcaaggt tgtaatactc tcaacttctg tattttgact tatccttcta
    24361 atttctaaga tgatatttgg tagaataaaa tcttctaaaa aaatgacctt aggtagatta
    24421 tttccttcag ctagataatc ttcatatttt tttctttgaa cctcaggtgc aataattact
    24481 acatttctgt tatacagata ttttagttta acaacccgtg cagaatatct aaataatact
    24541 atatgcatgt taatcccaat cctttcaatt attagtcatc atatccattt ggatgtttct
    24601 gttgccattt ccacgtatct tggcacattt tcataatatc ataccttggc ttccatccca
    24661 gtagctcttc tgcttttgaa atatctgcaa ttgaaacgtc catatctcct gctctccttg
    24721 aagttatctt atatggaata tacgagccta tgacactctc taagctgtgt aggatttcaa
    24781 atacactaaa accaacacca cttcctaaat tgattacttc atataaacct tcatctgtat
    24841 taaaaatata ctctaatgct tttctgtgtc cgtatactaa atcgttaacg tgaacatagt
    24901 cccttataca agtcccatca ggagtactgt aatcaactcc gaatatattt aaatatggta
    24961 attttccaat tgcaacttgt gtaatgtaag gaacaagatt attcggaatt ccatttggat
    25021 cctctcctaa atcaccactt tcatgtgcac ccaatggatt aaaatacctc agacaaacaa
    25081 ttttccaatt tgaattcgaa ataaacaaat catttaaaag tacttctata tactgttttg
    25141 ttctcccata cgggtttgaa gcttttaatg gattagtctc atagaatggc atgataggag
    25201 tactttcgta tacagtagct gatgaactaa acacaaaatt aaatacctta tattttttca
    25261 ttagttttaa aatatttata gttgataata aattattttc ataatacttc aatggttcaa
    25321 ccacggattc tccaacagct ttataccctg caaaatgaat tactccatca aaattatgtc
    25381 tcttaaaaac attttccaat ttttcttcat tttttaaatc aattttataa aaatgaagat
    25441 ttctactctt cttggatatc tgcttaatag actcaataac ttttttctta gagttactca
    25501 aatcatcaat gattgttact tcataattat tatctaacaa gtccaaaact gtatgtgatc
    25561 ctatgtatcc tgctccacct gttattaata atgatttcat gctaatttac ctccatattc
    25621 tttataccat taatttgaaa tttatcttgg ctaaaaatta ccctatttga ttttgcttca
    25681 cttccaagaa agttaccgat agaaatttct ggaaattcaa aaatctttct agactctaat
    25741 ttatatttgt ctatgtctaa caaagtatat tttccatatt gattaaccag attggaatta
    25801 ttaaacaaga tcaagggata gttatactcc cttggtaatt ctgctgtaat gattgaattt
    25861 tgatttttaa attcgaagtt aaattcacaa atcccttccc taaaaaaatg aagctctgca
    25921 tcatcaaata catagttaca gtccaattcc ttatgaaaac ctagataaaa tcctcttatt
    25981 aacgaatagg gatttgaaac atatgataca accggaaaat taaaataatc ttctccaata
    26041 caaagaggta tcttaaagat tatttctgta tataagattt cattattttc attaatttct
    26101 gaatacatat cagaaaaggt aagatagaat gattctactg attgtagttg tcgatacaat
    26161 tcttgatcta gagacttaac atctgggtat aatacactag catcaactgc tttatttagt
    26221 ttaacttcta gagttatatt attaccttta aatttatttg gtaatcttat catagttacc
    26281 ctcccacttt aatttttaat attttagaaa ctattttgtc aaactcttca atagaaagtg
    26341 aagtatcaat aaatggaata tctgtaaaat atc
//
LOCUS       DBEJZJ010000028        23158 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000028 DBEJZJ010000000
VERSION     DBEJZJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.28"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(148..618)
                     /locus_tag="ACL3R8_001457"
     CDS             complement(148..618)
                     /locus_tag="ACL3R8_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1314317.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(635..2908)
                     /locus_tag="ACL3R8_001458"
     CDS             complement(635..2908)
                     /locus_tag="ACL3R8_001458"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR1314318.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3255..6356
                     /locus_tag="ACL3R8_001459"
     CDS             3255..6356
                     /locus_tag="ACL3R8_001459"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR1314319.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            6439..7446
                     /gene="pfkA"
                     /locus_tag="ACL3R8_001460"
     CDS             6439..7446
                     /gene="pfkA"
                     /locus_tag="ACL3R8_001460"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR1314320.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADSKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            7505..9010
                     /gene="pyk"
                     /locus_tag="ACL3R8_001461"
     CDS             7505..9010
                     /gene="pyk"
                     /locus_tag="ACL3R8_001461"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR1314321.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(9188..9535)
                     /locus_tag="ACL3R8_001462"
     CDS             complement(9188..9535)
                     /locus_tag="ACL3R8_001462"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1314322.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDKYITIAKTFVEIHLNFLINLC
                     ISYFILNENQRAN"
     gene            complement(9867..9974)
                     /locus_tag="ACL3R8_001463"
                     /pseudo
     CDS             complement(9867..9974)
                     /locus_tag="ACL3R8_001463"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
     gene            complement(10084..10338)
                     /locus_tag="ACL3R8_001464"
     CDS             complement(10084..10338)
                     /locus_tag="ACL3R8_001464"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR1314323.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPSRQGKVLTYAERQLYDQKNEVS"
     gene            10774..11646
                     /locus_tag="ACL3R8_001465"
     CDS             10774..11646
                     /locus_tag="ACL3R8_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR1314324.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPTDDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(11779..12136)
                     /locus_tag="ACL3R8_001466"
                     /pseudo
     CDS             complement(11779..12136)
                     /locus_tag="ACL3R8_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12279..12590
                     /locus_tag="ACL3R8_001467"
     CDS             12279..12590
                     /locus_tag="ACL3R8_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314325.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
     gene            12594..13310
                     /locus_tag="ACL3R8_001468"
     CDS             12594..13310
                     /locus_tag="ACL3R8_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR1314326.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(13439..14254)
                     /locus_tag="ACL3R8_001469"
     CDS             complement(13439..14254)
                     /locus_tag="ACL3R8_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR1314327.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(14251..15156)
                     /locus_tag="ACL3R8_001470"
     CDS             complement(14251..15156)
                     /locus_tag="ACL3R8_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR1314328.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(15157..15288)
                     /locus_tag="ACL3R8_001471"
     CDS             complement(15157..15288)
                     /locus_tag="ACL3R8_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR1314329.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKAKAEKKN"
     gene            15568..17697
                     /locus_tag="ACL3R8_001472"
     CDS             15568..17697
                     /locus_tag="ACL3R8_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR1314330.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGKKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            17684..18133
                     /locus_tag="ACL3R8_001473"
     CDS             17684..18133
                     /locus_tag="ACL3R8_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR1314331.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            18192..18464
                     /locus_tag="ACL3R8_001474"
     CDS             18192..18464
                     /locus_tag="ACL3R8_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR1314332.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGRFW"
     gene            complement(18818..19009)
                     /locus_tag="ACL3R8_001475"
     CDS             complement(18818..19009)
                     /locus_tag="ACL3R8_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314333.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            19437..20195
                     /locus_tag="ACL3R8_001476"
     CDS             19437..20195
                     /locus_tag="ACL3R8_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314334.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            20197..22185
                     /locus_tag="ACL3R8_001477"
     CDS             20197..22185
                     /locus_tag="ACL3R8_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314335.1"
                     /translation="MFRLTNKLAVLNLIKNRKLYYPFALAVLLAVTLTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVIITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDNGYKIKEKEVFRYTYFGVANQEGNKLTFFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(22227..22901)
                     /locus_tag="ACL3R8_001478"
     CDS             complement(22227..22901)
                     /locus_tag="ACL3R8_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR1314336.1"
                     /translation="MDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(22843..>23158)
                     /locus_tag="ACL3R8_001479"
     CDS             complement(22843..>23158)
                     /locus_tag="ACL3R8_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1314337.1"
                     /translation="DVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRNRFKFCRSFKYPARRCS
                     WC"
BASE COUNT         7057 a         4200 c         4932 g         6969 t
ORIGIN      
        1 aaggcgacgt tgacgcggat tgaagagatt ttcgaagagt ataaatcttc ctaggataga
       61 gcaaaacgca tagtatcaag ggttttctga tgttaaagac tttctaccag gtttttttaa
      121 agcataattg ttagttgtag tcatttatta ttcttcaaag aaaaatggtg gggcgaattt
      181 tttcagttct tcaaagcact tttgagcagt atctgcatct tcacagatga taagacagac
      241 atcattacca caaagggtag cgatagcgtc agggaagctc aaagtatcaa tgatagaacc
      301 aaaggattga gccagtccag gaagggtttt tagtaggact tggtgttgaa ctgggcgcat
      361 ccagacaagg gcgtcttcca tgtagagttc gagacgtttt tcccattttg agatggaacc
      421 attgttaaga acataataag cgctatcttc ttcgcggact tttgataggt tcatattttt
      481 gatgtcgcgt gagagggttg cctgggttac ttgaatgtcg ttctcagcaa gaagggcttg
      541 caactcagcc tgtgtatgaa tcttgttttt tgtgataaga gcgcgtataa gttggtggcg
      601 gtgttctgat ttattcataa taatgtaact ccttttagca aggtaaggta agcatggact
      661 gagcgaggtc gacagtcaag tggtagtctg tattgtcacg gatggtgatt tcaaagtcag
      721 tagtatagag gactaaacgg agagtgtctc cttcttttag cttgtaaata gttggctgca
      781 gttcaaattg aacgtccatc cattcatctg cagtaatatc ctctactaac agtaaatcat
      841 ttctattttg taaattaagg taaccttttg tcacgactcg ttgtgcctct ggtctaaatg
      901 gcaattcaca gagattttcc aacatgtgat agcgaccgtt atcaatggtt ctagcactta
      961 aaatagctgg ataaggttgt aggtatttct tttgcccaaa ttctagcagt tgggcagata
     1021 agagcccctt gtttgtactg gatttgatac gaagattgag ctgagcgcga ccgtttaggt
     1081 ggagatcttt agtcacagga aggttaatag taatctgatt ggctttccct tgatagagct
     1141 ctgtattgaa ggtttggtat gtcttaccat agcgctcaaa atccttatct gggtactggt
     1201 tttgaatagc ttgctcttct tgaccaagtg agaaggtttc acagttttct tgcccaccga
     1261 agttatcaag tgataaccaa gtctgtggag ctgtattgtc ctgccagata acagtaggaa
     1321 gttgaaagtc tgtttcctgt cctagtaatt tcttggtcaa taaggcattt atggactcac
     1381 ggaagtcaat tgattgccaa ttgttcatgt aaacatgagc accattatgg aaaaagagat
     1441 gcttgtgtat atgagtagga agagcatgga acatctggta aacatgaagt ggtttgacat
     1501 tccaatcctg agaaccatga gtaaagacaa cctctgcctt tactttatgg gcattgagca
     1561 gataattgcg gtcatgccaa aactgattgt agtccccagt ttttcggtct agctgagctt
     1621 tcactttttc taagtcagct tggtgagctt cattgccacg gatatagtcg ccagctaaga
     1681 gattacgaga ataggttaac tcagcaaggg agtcaaagtc ctcacctgga taaccacctg
     1741 ggctagtcac cagaccgttt tcacggtagt agttgtacca tgatgaaatt cctgcctcgg
     1801 caatgataac ttctaaacca tcgactcctg tagtcgcaag accattggac atggtaccta
     1861 gataggaaag tcctgttgta gcaacttttc cgtttgacca atcagccttg acttgacgct
     1921 ggcgcgtgtg atcagtaaag gcacggcaac ggccgttaag ccaatcgatg acatttttat
     1981 aagcctcgat ttgctggtag tctccattag tcatgaaacc tgtcgagtct ttggtaccaa
     2041 cacctgagac atagagattg gcaaagcctc tcggaaggaa gtagtcgttt agtgtatagc
     2101 tagagttgat gtgagttagc ttttcctcag cctctgctat aagctcagct ttaccttggg
     2161 gttggacgag atttagttga ggtttctcta gctcaatctt gtgaggaagc ttaacctcaa
     2221 gctcgccctc catcttgtag agagccttgt cactagcctt gtcattggtt ccctgatgat
     2281 aagggctggc tgtcatgatg gcagggattt ttccatcaaa acgagggcga ataatgctaa
     2341 cctttactag gtctgatagc cctttttggt cagtatcgac acgagactca acgtaaacga
     2401 cttcacgaat gacatcctgg ttagaaaaag tagccaaact cttgccgtta aagtagtggt
     2461 agtcattatc ctccggaata agaccatcac taacaagttg gtcgataaga gtatttcctt
     2521 ttttggtgcg agtattgagt aactgataga gattttcaat caagtcacca tatataatgg
     2581 gaaatccagt ttctttacga aaaacgtcac tatcttcgaa gtcaaccaaa taagaaaagc
     2641 ctaaaagttg aaaagcaaca gtataaaaaa tatctgctgt cagttcatct tctgattgaa
     2701 aaaatgtcag caggtctgtt tttttatcag ctgctaggat agaaagtggg tagttggtgt
     2761 cttgataagt gaaaaagaaa cgacgtaaaa aggtttcaag tgagtctttg tgattggctg
     2821 tattttgtaa atcaaagcca cattttttta gttcagataa gacattttct tttggaaaat
     2881 tgatataact atattgatta aaacgcatag aacctccata tagaatgaca gttaaggtta
     2941 ttatatcaaa aaaaaagcag aaagggaatt gttaacttca aaaggaaata atccaataaa
     3001 aatgaataaa gtactaaatt caatatagag aacagagtaa caataagaat aaatagatag
     3061 ggtataaaag ttctaggaga tttatattat atgctttcta tttttatata taatatagta
     3121 taaatataaa aatgatgaca aaaatacaaa tggatagaaa ataaattagt aagctgatga
     3181 aatttttctc aagagaagcc atttataggt gaaaatggta taatatagtg agaaggatag
     3241 aggagaagtg taaattgatc gcacaactag atacaaaaac agtctatagt tttatggaaa
     3301 gcgtcatttc gatcgaaaag tatgtgagag cagctaaaga atacggctac actcatttgg
     3361 ctatgatgga tattgacaat ctttatggcg ctttcgactt tctagagatt acaaaaaaat
     3421 acggcattca tcctttgcta gggcttgaaa tgacagtgtt tgtagatgat caggaagtga
     3481 atttgcgctt tttagctcta tctagtgtgg gctatcagca gttgatgaag ctttcgacag
     3541 ccaagatgca gggggagaaa acttggtcag tcctgtccca gtacctggag gatatcgcgg
     3601 tcattgtgcc ttattttgat agagttgagt cgttagaact aggctgtgat tactatatag
     3661 gggtttatcc agaaacacta gcaagcgaat ttcatcatcc tatcttacct ctttatcggg
     3721 tcaacgcttt tgaaagcagg gatagagaag ttcttcaagt tttaacagcg attaaagaaa
     3781 atctaccgct cagagaagtt cccttgcgtt cgagacaaga tgtctttata tcagcaagtt
     3841 ctttagagaa actattccaa gagcgttttc cgcaagcttt ggacaattta gaaaagctta
     3901 tttcaggcat ttcttacgac ttggatacta gtctgaaact gcctcgtttt aatccagcta
     3961 gaccagcagt agaggagttg agagagcgtg ctgaactggg gcttgttcag aaggggttga
     4021 ctagtaaaga atatcaagat agactagacc aagaattgtc tgttattcat gatatgggct
     4081 ttgatgatta tttcttggtt gtttgggatt tgttgcgttt tggacgatcg aatggctatt
     4141 atatgggaat gggaaggggt tctgcagtag gcagtttggt ttcttatgcc ttagacatca
     4201 cggggattga cccagtagag aaaaatctga tttttgaacg ctttcttaat cgtgaacgct
     4261 ataccatgcc tgatattgat attgatatcc cagatattta tcgtccagat tttatcagat
     4321 atgttggtaa taaatatggt agtaaacatg cggcacaaat cgttactttt tcaacctttg
     4381 gagccaagca agctcttcga gatgtcttga aacgctttgg tgtgccagag tatgaattat
     4441 ctgcaattac taagaaaatc agttttcgtg acaatcttaa gtcggcctat gagggcaatc
     4501 tccagtttcg tcagcaaatc aatagtaagt tagaatacca aaaagctttt gagattgctt
     4561 gcaagataga gggctatcca aggcaaacct ctgtccatgc ggctggtgtt gtaattagtg
     4621 accaagattt aaccaactac attcctctaa agtatggtga tgaaattcca ctgactcagt
     4681 atgatgctca tggagttgag gctagcggac ttttgaagat ggactttctg ggactacgaa
     4741 atttgacctt tgtccagaag atgcaagagt tgcttgctga aacagaaggt attcatctga
     4801 aaattgaaga aatcgattta gaagacaaag aaacgttagc tttatttgcc tctggtaata
     4861 caaaaggtat ctttcaattt gagcaaccag gtgccattcg tctgcttaag cgtgtgcaac
     4921 cagtctgttt tgaagatgtc gtcgcgacta cttctctaaa tcgaccgggt gctagtgact
     4981 atatcaataa ttttgtggca agaaagcatg ggcaggaaga agtgactgtt ctggatccag
     5041 tactggagga tattttggct ccaacctacg gcataatgct ctatcaggag caggttatgc
     5101 aggttgccca gcgatttgct ggatttagtc ttgggaaggc cgatattttg cgtcgagcta
     5161 tgggtaaaaa ggatgcttct gctatgcatg agatgagggc ttcctttatt caaggctcca
     5221 tagaagcagg ccatactgcg gaaaaagcag agcaggtttt tgatgttctg gagaagtttg
     5281 caggctatgg ttttaacagg tcacacgcct acgcctactc agccttggcc ttccagttgg
     5341 cttattttaa aacacattat ccagccatat tttatcagat tatgttgaat tctgctaaca
     5401 gtgattatgt aacagatgcc ttagaagcag gttttgaagt agccccattg tccatcaaca
     5461 cgattcccta tcacgataaa attgccaaca aggccatcta tctaggtttg aaatccatta
     5521 aaggagtcag taatgattta gctctctgga ttattgaaca tagaccttat tctaacattg
     5581 aagattttat agctaaatta cctgagaatt atctgaaact tcctctgcta gaacctttgg
     5641 taaaagttgg tcttttcgat tcatttgaaa aaaatcgtca aaaagtattt aataacttag
     5701 ctaatctatt tgaatttgtg aaagagttgg gaagtttgtt tggagatgct atttatagtt
     5761 ggcaggaatc ggaagattgg acggaacaag aaaaatttta tatggaacaa gagcttttag
     5821 ggataggtgt cagcaaacat ccactacaag ctattgcaag taaggctatt tacccgatta
     5881 ccccaatcgg aaatttgtca gaaaatagct atgctattat tttggttgaa gttcagaaaa
     5941 taaaagtgat tcgtaccaaa aagggtgaaa atatggcctt cttacaggca gatgatagta
     6001 agaaaaaatt ggatgtcact ctcttttcag acttatatcg tcaggttgga caggaaataa
     6061 aagagggagc cttctactat gtaaaaggaa aaatacaatc acgtgatggc cgtctgcaaa
     6121 tgattgcaca agaaataaga gaagcagttg ctgaacgctt ttggatacag gtgaaaaatc
     6181 atgaatcgga tcaagaaatt tcacgtattt tagaacaatt taaaggccca atcccagtca
     6241 tcatccggta tgaagaggaa cagaaaacca tcgtttctcc ccatcatttt gtagctaaat
     6301 ccaatgaatt agaggagaaa ttgaatgaaa tcgttatgaa aacgatttat cgctaaaaat
     6361 acggaaaata gaagaatttt aaaatcaaat gtgatataat caagaagaat gttaaaagaa
     6421 aaaggagcat aaaccaatat gaaacgtatt gctgttttga ctagtggcgg agacgcacct
     6481 ggtatgaacg ctgctatccg tgcagttgtt cgtcaagcaa tttcagaagg aatggaagtg
     6541 tttggtatct atgacggata tgctggtatg gttgccggtg aaattcatcc cctagatgca
     6601 gcttcagtag gagacatcat ttctcgtggt ggtacttttc ttcactcagc tcgttatcca
     6661 gagttcgctc aacttgaagg gcaacttaaa gggattgagc aattgaaaaa acacggaatt
     6721 gaaggtgtag ttgttatcgg tggtgacgga tcttaccacg gcgctatgcg tttgactgaa
     6781 catggcttcc cagctattgg tcttccaggt acaatcgata acgatatcgt tggtactgac
     6841 tttacaatcg gttttgacac agcggttact actgccatgg acgctattga taagattcgt
     6901 gatacatcat caagtcaccg tcgtactttt gtaatcgaag ttatgggacg taacgctggt
     6961 gatatcgctc tttgggctgg tattgcaact ggtgctgatg aaatcatcat ccctgaagca
     7021 gactccaaga tggaagatat cgtagcaagc atcaaagctg gttatgaatg tggtaaaaaa
     7081 cacaatatca tcgtcttagc tgaaggtgtg atgtcagcgg ctgaatttgg tcaaaaactt
     7141 aaagaagctg gagatacaag cgaccttcgt gtaacagaac ttggacatat tcaacgtggt
     7201 ggttctccaa ctgcgcgtga ccgtgttttg gcgtcacgta tgggtgcaca tgctgttaaa
     7261 cttcttaaag aaggtatcgg tggtgttgcg gttggtattc gtaacgaaaa aatggttgaa
     7321 aatccaattc ttggtactgc agaagaaggg gcattgttta gccttactgc agaaggtaag
     7381 attgtggtta acaacccaca caaagccgat attgagctat ctagcttgaa taagagcttg
     7441 tcataattta caatttagtt aataagacca aaaaggtcat atatataaag gagtcacaaa
     7501 aatcatgaac aaacgtgtaa aaatcgttgc aactttgggt cctgcggtag aaatccgtgg
     7561 tggtaaaaaa ttcggtgagg acggatactg gggtgaaaaa cttgatgttg aagcttcagc
     7621 taaaaacatt gctaaattga ttgaagctgg tgctaacaca ttccgattca acttctcaca
     7681 cggcgaccac caagaacaag gtgagcgtat ggcaactgtt aaacttgcgg aaaaaattgc
     7741 aggtaaaaaa gttggtttcc ttcttgatac aaaaggacct gaaatccgta cagaattgtt
     7801 cgaaggtgaa gctaaagaat attcatacaa aactggtgaa aaaattcgtg ttgcaactaa
     7861 acaaggaatc aaatcaactc gtgaagtgat tgcgttgaac gttgctggtg ctcttgatat
     7921 ctatgatgat gttgaagttg gtcgtcaagt tttggttgac gatggtaaac ttggtcttcg
     7981 tgtggttgct aaagatgatg aaactcgtga atttgaagtt gaagttgaaa acgatggtat
     8041 catcgctaaa caaaaaggtg tgaacatccc taacactaaa attcctttcc cagctcttgc
     8101 tgaacgcgat aacgacgata tccgtttcgg tcttgaacaa ggtatcaact tcatcgcaat
     8161 ttcattcgta cgtactgcaa aagatgtgaa cgaagttcgt gcaatctgtg aagaaactgg
     8221 aaacggacat gttcaattgt tcgctaaaat cgaaaaccaa caaggtatcg ataacttaga
     8281 cgaaatcatc gaagcagctg atggtattat gattgctcgt ggtgatatgg gtatcgaagt
     8341 accgttcgaa atggttccag tttatcaaaa aatgattatc aagaaagtca atgctgcagg
     8401 taaagttgtt atcactgcaa caaacatgct tgaaacaatg actgaaaaac cacgtgcaac
     8461 tcgttcagaa gtatcagacg tattcaacgc tgttatcgac ggaactgacg ctacaatgct
     8521 gtcaggcgag tctgcaaacg gtaaataccc actcgagtca gtaactacaa tggctacaat
     8581 cgacaagaac gctcaagctc ttcttaatga atacggacgt cttgattcag attcatttga
     8641 gcgtaactct aagacagaag taatggcttc tgctgttaaa gatgctacta gctcaatgga
     8701 tatcaaattg gttgtaactc ttactaagac aggtcatact gcacgtttga tttctaaata
     8761 ccgtccaaat gctgacatct tagcattgac atttgacgaa ttgacagaac gtggcttgat
     8821 gttgaactgg ggtgttatcc caatgttgac agatgctcca tcttcaactg acgatatgtt
     8881 cgaaatcgct gaacgtaaag cggtagaagc aggtctcgtt gagtcaggcg atgatatcgt
     8941 tatcgttgct ggtgtgccag taggagaagc tgttcgcaca aacacaatgc gtatccgcac
     9001 agtacgttaa gaaaaatata aaaacctatc atatccagct ttctagtctg tatgatgggc
     9061 tctttttttg tccagggggg caaaaagggg gcaaaacttt cataatggat tgatactctt
     9121 cgaaaatcaa attcaaacca cgtcagcgtc gccttaccgt actcaagtac agcttgcggc
     9181 tagcttccta gtttgctctt tgattttcat tgagtatgaa ataagatatg cacaaattga
     9241 ttaggaaatt caaatgaatt tctacaaatg ttttagcaat cgtaatgtac ttgtctagat
     9301 tcgatctgat atattttcga tttaatgata tggtatttaa aacctccaaa gtagcttgct
     9361 ccattctttt acttacgtga gtgtagatgt tatttactgt tttagcgttt ttgtgttcca
     9421 ctctaaccat tatagcattc ttctcagcta gtgtactaag gagtgtgtgc ctgaaaatat
     9481 gggaactaag gggctggttt atcggtttct ctagtttagt atttgccttt tgcaaagtga
     9541 tgttaaatgc ctttctctaa atttacatat cactattgtt taacaaaatc taatctactt
     9601 taggtcactt attctttttt tgaaatgtag aatgaacttt ttcaaagttt ttcgaatctt
     9661 ttaaaatctg tttgttttat atcgccattc tccccctttt ttaattctcc ctatatagcc
     9721 tgacaacttt cccgatggta cgaatatggt tgctttcgtc taggtggatg tcggggtatt
     9781 tgggattgag tttttttaag gtagccttgg cggagtttct tgacatagtt agcgccgtct
     9841 acttggaaga tgccgatggt attatagtca atctgtgggg tattcttgat aaataggtag
     9901 tcgctgtttc ttatctttgg ctccatggac ttgctgatga cataagcgat tgggtcgtag
     9961 tcgtctggga taatggaaac tccatatcta aatcgttgtc ctgcatcgag cggctacctg
    10021 cagagataaa ctatctaaca cgagagtaag tagtctgtct gtagtcgtcc agtctgatga
    10081 tttttacgat acttcgtttt tctgatcata cagttgcctc tcggcatagg tcagaacttt
    10141 accttgtctg gatggtgccc gttggtcgta gatagattgg atatcgctag gagaatcctt
    10201 ttgaactgga gaaaagaggg catcaatcaa gctactgaat actttaacta agtcaaatat
    10261 agtatttttc ttagtagacc taaccctttt ttcataattt ccaatggtgt ttttacttat
    10321 accaatctta gtacccaatt cttattgagt tcaaccatta ctagtctata ttgttttata
    10381 gttgattgag tttggaatag tacgctgtag ctgctaaaac atttctagga attaatttgc
    10441 ctttcctaat agagttgttc atatcttatt tcaatctact atatttttcg cctctaacaa
    10501 tcgcaatctc ttctttatct acgaacgaaa tcgctttcta tttttgtaag taaagcatca
    10561 cacgaaatcc acgaaaatga aaacctttgt tgtgttttcg taaaaaattt gttgacagag
    10621 cacgaaacgc ctactataat taaatcaagc ttaaggaaat aacaaaaaaa caaatcggag
    10681 ggaaagacga tgaacacatt aaatgagaaa gtaatcaata tctgtaaagc aatagttaaa
    10741 gaaactttaa tccaagacat ttaggagaaa gaaatgaaga aatcaagaaa attagccaca
    10801 ttaggaatct gttcagcttt gtttttaggc ttggctgctt gtcaacaaca acatgctact
    10861 tctgagggga cgaatcaaag gcaaagcagt tcagcgaaag ttccatggaa agcttcatac
    10921 accaacctaa acaaccaggt aagtacagaa gaggtcaaat ctctcttatc agctcacttg
    10981 gatccaaata gtgttgatgc attttttaat ctcgttaatg actataatac tattgtcggc
    11041 tcaactggct tatcaggaga tttcacttcc tttactcaca ccgaatacga tgttgagaaa
    11101 atcagtcatc tctggaatca aaagaagggc gatttcgttg ggaccaactg ccgtatcaat
    11161 agttattgtc ttttgaaaaa ttcagtcacc attccaaagc ttgaaaagaa tgaccagttg
    11221 cttttcctag ataatgatgc gattgataaa ggaaaggtct ttgattcaca agataaggaa
    11281 gagtttgata ttctattttc gagagttcca actgaggcaa ctacagatgt caaggttcac
    11341 gctgaaaaga tggaaacatt cttctcacaa tttcaattca atgaaaaagc tcgaatgctg
    11401 tctgtagtct tgcacgacaa tctggatggc gagtatctgt ttgtaggcca cgttggggtc
    11461 ttagtaccta ctgatgacgg tttcttattt gtagagaaat tgactttcga agagccctac
    11521 caagcgatta aatttgctag taaggaagat tgctacaagt atttaggcac caagtatgcg
    11581 gattatacag gcgagggact ggctaagcct tttatcatgg ataatgataa gtgggttaaa
    11641 ctttaatagt gttatgatat gacagtaatc ttaggatttt tatttctatt tttgatgagt
    11701 tggtgggtta tttcaatcgt taatagccag aaaccacgca aaaatgaaac atttattggc
    11761 tatatccaaa gatacgatat tgatgggaat ggctatcaat cattaccgtg tcctcagaac
    11821 tgagaggagt tcttgaaatc gtaaaactac tttgaacaag agttacttca acccattgga
    11881 tccgacggag taagttgctt tcgtggatac caaaaacagc cgcaatttct tcataagtgc
    11941 ggtattctcg cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt
    12001 ttcgtccccc ttttgtgtgt ttaagttgat aagctgtttt taatacagct aatatctctt
    12061 caaaagtggt gcgctgaaca ccaacaagac atttaaatcg tgcatcagtt agttgtttac
    12121 ttgcttcata attcatagaa ctactatacc atattttgtt tcgcaggaag tctaatgcta
    12181 aaatcttatc agtgagaaga tttcttaaag tttattcttt gtaatttcat ctgtattagt
    12241 acataattta acttagagaa aataggagga ctaatcgaat ggaattaaaa gattttacag
    12301 aaaaagaaca ggaaatgatt aagaaaaggc ttacaatgtc taatattagt gacaaagaaa
    12361 ctactgagaa gattctggcg ctagtaccac aagacttgat taagcgaatc ccgttttttg
    12421 tcagaaaaca tgctacaaca cgtacgatta aacgcatttc aattgaacac cctgaactct
    12481 acgctgtagc tcaaacaagt ggtgagattc cagaaaaaga atgcgaagaa ttgcgtcaga
    12541 ttatcacaac tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa
    12601 aatattttat tggcggtttg ggaagcaatg cctatcatag caaggatttt cttcaagaac
    12661 tagattcgca ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat
    12721 tgaaatcatg gtttaaaaat gagattgtag aggaagaatt tatctgtctg ataggtcatt
    12781 ctcttggagg agatttagct cgttatctcg catcggaatt tgaagaagta aagaaactga
    12841 ttcttttgga tggtggctat ctagatttag ataagatttt acctttggat acagagttag
    12901 aggaaactaa aaattatatc aaatctcaaa ttgttttgga cttagatgtt cttacttcta
    12961 aagaaaaatc tgaagcaaag cattggtcag aaaatatgga gaaagctgta agacagtcct
    13021 atcactggaa tgttgagtat aatagatatg agttggctat aaattatgaa aatatagaag
    13081 cgatactccg cctacggaga aaaatacaag cttttaagag agaagtggga gataccttgt
    13141 ttattagtcc tcgctatcct aatgaagcta catggagaga ggaagcccta aaagaattgc
    13201 cagactattt tgatactatt tttttagaaa actttggcca tgagctttat actcaagcac
    13261 ctaaagaaat cgctagtcta atgaatgagt ggctcgctta ttttctatga gctacttgta
    13321 ttgctggaaa tggtataaga tgaaaatcta caagtcacta attttcatat aacaaaaaac
    13381 gaacaggctc tttttctgtt attcagaaga gaacttgttc gtttttatct tgattttctt
    13441 aaaaagctct atatacatag ggattttctg gtttatcgac tttggtaaag ctgtcgattt
    13501 ccaaggttgg aaggttttgt ttgagttctt tatggtagtg attgaccagt tttcctttgg
    13561 ctgttatcca agtgttgttt tcatactgcc gggtattgcc cttggtcagc aatccataga
    13621 caccagaatc tgcgatacag tggataatgc cgaatcggaa cagaaattga ctattggcat
    13681 gactggggtc gttatagaca aagcctgtaa actggattgt cttgccctca aactcatctg
    13741 gatagtcgta gatagcctcc atgacttcca tatagttttc attagtgacc tgaatactat
    13801 cttgggataa gtatttatcc gccgccgttc gcatttcctt ttcataggct gattttgaaa
    13861 aataagaact ggtatctggt ttcaaatatt ggcttgtcgt cccttcgctt gtctgaatgg
    13921 ctagatccgt tccttccgat agggggaaat gataaccttt agcagaaaca gtctgagaat
    13981 ccaagctaac agttgggaaa gttaagccga tgacaagtgg aatagccaga agagaaatac
    14041 tcgtcatctt ggctaatcgg ctgttcagat gactgtgggt tttgacttgc ttcatccaga
    14101 tatacaattg aacgatagcc aagataaaag aaagcaccat ggagatatag gccagatagg
    14161 aatagtgcat gttgatgtac tggtttagtt tgcccgacag atggaggtaa atagtcagtt
    14221 caaaatagcc agctaaaact aaaaatcgaa tcataggatg actccaatca agagagaata
    14281 ggctaaaacg accagagtca caatcgtaat gaagtgacta ataaatcgtg ctttcaagta
    14341 atttttcatc ataagaatat ttttgatatc cagcattggg ccaatgacga gaaaagccag
    14401 aactggagcc aaaccgaaac tcgagagtag agaagccccg ataaaggcat ccgcctcact
    14461 acagagcgaa agaagaaagg ccaaaatcat caagagcagg atggcaaaaa gaggagtcgc
    14521 actgatagag gtcagaatcc gagtcggaac ataaacctgt ataacagagg caaagagaca
    14581 gccaaatacc aaataacgtc ccgtatcaaa aaactcatca atggcttgca caaagacctg
    14641 aaaaactttt tttgcaggac ttaagtgaga aaaatcatgc tcatgacagg ctagacgatt
    14701 ttctttttga atcggttctt gccagaaaaa tcctagaaaa attcctagta ttacagccac
    14761 aacgatggaa cccagagctc gtaatagggc gacatggaag gagttgccaa aggcagaata
    14821 ggtcgcaaaa agaacaatgg gattgataac aggtgctgtc acaagaaaag gaacggccgt
    14881 gtaacttgga accttttttt ccagaaaacg attgatgatg gggacgattc cacattcaca
    14941 ggaagggaaa agtataccga caaaggtccc aaaaaagatt ctcccccaac gatttcgagg
    15001 gagaaaatga taaaccttgt caggtgtgat ataaacttca atcagccctg agacaatact
    15061 tcctatcaga acgaagggaa gggcttcaat gataatggag agaaaaatgg ctccagtttg
    15121 aagtacacta gatgggagtt gttgaaaagc agtcatctag tttttctttt ctgctttggc
    15181 ttttttctct ttgtcatcag ggaaagtgac ttgtttcaaa tcagggagtt tagcaaactc
    15241 ttcaaacatc ttgtccaagt cgtctcgttt tgtaaatttg acagccatag gtgtacctcg
    15301 attctaaatt ctacctctat tatactatta ttttgcggaa aagggagttt tttaatttgt
    15361 tttcgatagt tgatactctt cgaaaatctc ttcaaaccac gtcagcttcg ccttaccgta
    15421 gtacggttac tgacttcgtc agttctatcc acaacctcaa aacagtattt tgagcagcct
    15481 acggctagct tcctagtttg ctttttgatt tttattgagt atgaaaagga ttggagaaag
    15541 ccttccagct tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggat
    15601 ttgggagtga cgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact
    15661 attcccttta tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt
    15721 aaggctatta ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc
    15781 ttagctaaga ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt
    15841 gccgaaaaat tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc
    15901 aaggcaacca ttgcccgtga agctggactc tttcctcttg ctcgcttgat tttgcagaat
    15961 atagttgact tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag
    16021 gaagccttga ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg
    16081 cgttctatga cttatcagga agtgctgaga cactctaaac tcacttctca agccaaggat
    16141 gaaagtcttg atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga
    16201 actatgcaag gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag
    16261 atcggttttg aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg
    16321 aaaaatgctt atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct
    16381 attgagcgtc gtattcggac agaattaact gagaaagctg aagagggagc tatccaactt
    16441 ttttctgaca atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt
    16501 gggtttgacc cagcctttcg tacaggtgcc aagctagctg tcgtggatgc aacaggaaaa
    16561 atgctgacaa ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa
    16621 gccaagaaag atttagcaga tttaattggt caatacggtg tagagattat tgccattgga
    16681 aatggaacgg ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct
    16741 gaagtcagct atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt
    16801 gctcgtcagg agtttccaga cttgaccgtt gaaaaacgct ctgccatttc tatcgcccgt
    16861 cgtttgcaag atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt
    16921 caataccaac acgatgtcag tcagaagaaa ctctctgaga gtctggactt tgttgtcgat
    16981 acagtggtta accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac
    17041 gtagctggac tcaataaaac catttctgaa aatatcgtca aataccgtga ggaagaggga
    17101 aaaatcactt cacgctccca aatcaagaaa gttcctcgtt tgggggccaa ggcttttgaa
    17161 caggctgctg gtttcctccg tatccctgaa agtagcaata tccttgataa tacaggagtt
    17221 catccagaaa attacgctgc cgttaaggaa ctcttcaaat gcttggacat taaggatctg
    17281 aatgaagagg cccaaagcaa actcaagtcg ctttcagtca aggaaatggc gcaagagtta
    17341 gaccttggtc cagaaactct taaagatatc attgcagatc ttctcaaacc aggtcgagat
    17401 ttccgtgatt cctttgatgc tccagttctc cgtcaagatg tcctagatat caaggactta
    17461 gtggttggaa aaaagctaga aggagtggtg cgtaacgttg ttgatttcgg tgcttttgtt
    17521 gatatcggaa ttcatgagga cggtctcatc catatttccc atatgagtcg caagtttatc
    17581 aaacacccta gtcaagtggt ggcagttgga gatttggtga gcgtttgggt taagaaaatt
    17641 gatactgaac gtgaaaaagt taatctgtct ctcctagctc caaatgaaac tgactgatta
    17701 cgtcaagcag gtttcactag aagacttcgg cagacctttt atccatcatg tccagtggaa
    17761 taggcgtcta cgttcgacag gtgggcgatt tttccccaaa gatgggcatt tggattttaa
    17821 tcccaaggtt tatcaggaac tggggttgga cgtttttagg aaaattgtcc gacatgaact
    17881 ctgtcattat cacctttatt tccaagggaa gggctatcaa cacaaggatc gggattttaa
    17941 ggaacttttg aaagcagtgg atggattacg gtttgtacca tccttgccca atagtaactc
    18001 taaaccactc aagctttatc gttgtcaatc ctgccagcaa aggtatcagc gcaagcgtag
    18061 gattgatacc aaacgctatc gctgtggact ttgtcgaggt aaattgcttc tgataaatca
    18121 gcctgaggac tgatgaaagc cgagcctccc cgtgatatac tatgtctaac ctagcagaaa
    18181 gaggaaatat catgaacagt aaattttata aaatgagacg caatcgcatg atttcaggag
    18241 ttctggcagg tctgtcagac aagtggaatt ttgatgttac cctagttcgt ttcttgtttg
    18301 ccatttttac agttgcaaac tttggacttg gcgtgattat ctatatcatc ctagcttcta
    18361 tcatgcctac caaggaagaa atcgaagcag aaatgtacgg aacaggccca cgtaaacgca
    18421 aagaagccca agccattgac gacaatgaag gcaggttttg gtgaggttct acagaagatt
    18481 tggaataagc aaaaagcttt aaatcaatag tctaaactgc ttgatttaaa gcttttttac
    18541 ttttatactc aataaaaatc aaagtgcaaa ctaggaagcc agccacaggc tgtaatttag
    18601 tcggcaatgt gaagttgaca tagtttgcac tttgattttt gaatagtatt aataatattt
    18661 cgccagcttc atccacaaac tatagtggat tggaactaga atagtacacc tctacttcta
    18721 aaacattgtt agaaatcgat ttgactatcc tgatcgattt gtcctgttct tatttcattt
    18781 tattataaaa gcagtaattt aaactcagtt ttttaatcta tttttgctgc tgagacaata
    18841 catttttgga aaaatggtgg atgctgataa caactgataa ccagcaaata acataagcag
    18901 tgccggtaaa ttctgtaccg ataaagtgtg tgtgttcaac taagagctga ccgatgaatg
    18961 gagagagcag atagagaagt ccgatgagta tatgttcttt gtgtttcatt aaagcgcacc
    19021 ttctttcctt ataggttgaa cgacttgcaa gtgttaaatt gaatggtatg ttatctaggt
    19081 aaccttacta aaatgttagt tcccgcttcc tccttttcaa agtaagcctt ttcacactta
    19141 tattttacaa ctttaaaaat aggaaatcaa atcattttct aagtaatttt gcttatattt
    19201 cacccaatct tacaaaaatg taagattaaa gtctcttttg taaggttagg ttatggcaag
    19261 cggtcttttt ttgatgtaaa ctagactcat aaagaacaaa ggagtaacat catgaaacaa
    19321 atcttacata agaaaactag aaaaccaagt cacaaagaaa ttgagcgcgt tcagctggga
    19381 tgcactatga tgcaagctac atttcatttg atgggatatt aagaaaggag attctcatga
    19441 cacttttaga tgtaaaacac gttcaaaaaa tttataaaac acgttttcag ggcaaccaag
    19501 tagaagccct caaggatatt cactttaccg tcgaaaaggg tgactacgtt gccatcatgg
    19561 gtgagtctgg ttctggtaaa tcaactcttc tcaatattct agctatgctg gataaaccaa
    19621 gtcgtggtca ggtttacttg aatggaactg acaccgcaac cattaaaaat tcacaggcct
    19681 ctagcttccg tcgtgaaaag ttgggctttg tcttccaaga ctttaacttg ctagatactc
    19741 tatctgtaaa ggacaatatc ttgcttccgc ttgtcttgtc aagaagacct attacagaga
    19801 tgatgaagaa attggtggtg acagctgaga atctgggaat aaaccaatta caagagaagt
    19861 acccttacga gatttctggt ggccagaaac agcgtgtagc agtagcacgc gccatcatca
    19921 ctgaacctga aattctcctt gcggacgaac cgacaggagc tcttgactcc aagtcatctg
    19981 cagccttact tgatgtcttt gatgaaatca atgagcgcgg ccaaaccatt ctcatggtaa
    20041 cccactcaac agcagcagct agcagagcta aacgtgtact ctttatcaaa gacggcattc
    20101 tttacaatca aatctaccgt ggagagaaga cagaacgtca gatgttccaa gaaatctctg
    20161 ataccttgac tgtcatggca agcgaggtga attagtatgt ttcgattaac caataagtta
    20221 gcggtattga acttgattaa aaaccgcaaa ctctactatc cttttgcgct ggctgttctc
    20281 ttggcagtca ctctcaccta tctcttttac tctctaacct tcaatcctaa gattgcggaa
    20341 atccgtggag gaacaaccat tcaggctaca cttggatttg gtatgtttgt cgtcaccctt
    20401 gcgtcagcca ttatcgttct ctatgccaat agttttgtca tgaagaaccg ttccaaggaa
    20461 ctaggaattt atggcatgtt gggcttggag aagcgtcatc ttatcagtat gacctttaag
    20521 gagttagtgg tatttgggat tctaactgtt ggagcgggta tcggtattgg agccttgttt
    20581 gacaagttaa ttttcgcttt cctgctcaaa ctaatgaaat tgaaggttga gctggttgct
    20641 accttccaga cgaaagttat cattacagtg cttgttgtct tcggtttgat tttcctaggc
    20701 ctcatgttcc tgaatgccct tcgaatcgcc cgtatgaatg ccctccagct ctctcgtgag
    20761 aaagctagtg gagagaaaaa aggtcgcttc cttcctctcc aaaccattct tggttccata
    20821 agtttaggaa ttggctatta tcttgccctt acggtaaaag atcctcttac agccttaaca
    20881 accttcttca tagctgtttt actggttatc tttgggactt atctcttgtt taatgcaggg
    20941 attaccgttt tcctccaaat cttaaagaaa aataagaaat actattacca accaaataac
    21001 ctcatatctg tttctaactt gattttccgt atgaagaaaa atgcagttgg actagcaact
    21061 atcgctattt tgtcaacaat ggttttggta accatgtcag cagcgacaag cattttcaat
    21121 tccgcagaat cctttaaaaa agttctaaat cctcatgatt ttggggtttc aggacaaaat
    21181 gttgaaaaag aagatttgga caaactcttg agccagtttg caagtgacaa tggttataag
    21241 attaaagaaa aagaagtgtt tcgttacact tactttggtg ttgcgaacca agaaggaaat
    21301 aagttaacct tttttgaaaa aggacaaaat cgtgtccaac ccacaacagt tttcatggta
    21361 tttgaccaaa aagattatga aaatatgact ggtcaaaaac tgtctctatc aggaaatgag
    21421 gtcggtctct ttgccaaaaa tgacggactg aaaggacaga aagctctaac tctaaatgat
    21481 catcaatttt ctgtcaaaga agaatttaat aaagatttca ttgtcaacca tgttccaaat
    21541 aagtttaata tcttgactac tgattacaat taccttgttg ttcctgattt acaagccttt
    21601 ttggatcaat tcccagattc ggctatctat aatcagtttt acggtggtat gaatgtagat
    21661 gccagcgaag aagaacaact caaggtcgct gaggagtatg aaaactacct caatcaattt
    21721 aatgctcaat tagacacaga aggtagctat gtttatggta gcaatctagc agatgctagt
    21781 tctcagatga gtgccctctt tggtggtgtc ttctttatcg gtattttcct atccattatc
    21841 tttatggtcg gaactgttct ggtcatctac tacaaacaaa tttctgaagg ctacgaagac
    21901 cgtgaacgct ttattatctt gcagaaagtc ggtttggacc aaaagcaaat caagcaaacc
    21961 atcaacaaac aggttttaac tgttttcttc cttcctttgc tctttgcctt catacatctc
    22021 gcctttgcct accatatgct tagcctgatt ttaaaagtga ttggtgtact ggatacgact
    22081 atgatgttga ttgtgacctt gtctatctgc gctatcttcc tcatcgccta tgtgctgatt
    22141 ttcatgatta cttcaagaag ttatcgcaag attgtgcaaa tgtaaaaaag atacctcgac
    22201 ttcaaaatcg aggtatttct tgtattctaa atgctgaaaa gttgttcgag caggaaggta
    22261 actcccatgg tcaagagacc aatagcaagg ttccgaatca tagctgttct agtcggatcc
    22321 tttccaagtc tggcactagt gtaaccagtg agaagaaggg ccacaccgac aataaggaca
    22381 gtagcaggga tgcgatattc acttgggaat atggtcactg acagcattgg aggcaaactt
    22441 ctaaggaaaa aggcaacgaa gctagaaatg gcagcgtgcc aaggattggt aaattcttca
    22501 tactcaatcc catatttttc ctctaccaga gccttgagtg gatttttaag aaagatctta
    22561 ttggtcaaga gttgggcaga agttttgcat tctccatttt ggatataagc agcatagagg
    22621 gattttttgg ctagttccct atcttggtct aacaagagtt tttctcgcga aacggcagct
    22681 tcctcggtat cttttggagt tgaaacggat acatattctc caccagccat tgaaaaggca
    22741 ccagctaaga tagccgcaaa tcctgataaa aagataatcc agatattggt cgtggcactg
    22801 gcaaccccga taaccacacc agcaatggaa ataattccat cgttagcacc aagaacacct
    22861 gcgcgcagga tatttaaacg acctgcaaaa tttgaatcga tttcgtgatt tgtttctgac
    22921 gctaaatttc aagttcaagt tagccatcca gaagtcttct ctgggtgact tgtagtccaa
    22981 gcatttttta ggatagttgt taatccactt ttcgatgaat gcgacttctt tgggagtcat
    23041 tttcttggtt cccttaggta accatctacg aatgagcctg ttgtgattct cattagttcc
    23101 cctttcccaa gaggcatagg ggtgcgcata atagatgtgc tcctcagaaa atacatca
//
LOCUS       DBEJZJ010000029        22544 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000029 DBEJZJ010000000
VERSION     DBEJZJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.29"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="ACL3R8_001480"
     CDS             complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="ACL3R8_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR1314338.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1929..2285)
                     /locus_tag="ACL3R8_001481"
     CDS             complement(1929..2285)
                     /locus_tag="ACL3R8_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR1314339.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(2287..4110)
                     /gene="dnaK"
                     /locus_tag="ACL3R8_001482"
     CDS             complement(2287..4110)
                     /gene="dnaK"
                     /locus_tag="ACL3R8_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR1314340.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4590..5114)
                     /gene="grpE"
                     /locus_tag="ACL3R8_001483"
     CDS             complement(4590..5114)
                     /gene="grpE"
                     /locus_tag="ACL3R8_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR1314341.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(5141..6175)
                     /gene="hrcA"
                     /locus_tag="ACL3R8_001484"
     CDS             complement(5141..6175)
                     /gene="hrcA"
                     /locus_tag="ACL3R8_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR1314342.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6339..6849)
                     /locus_tag="ACL3R8_001485"
                     /pseudo
     CDS             complement(6339..6849)
                     /locus_tag="ACL3R8_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            7457..9790
                     /gene="hsdR"
                     /locus_tag="ACL3R8_001486"
     CDS             7457..9790
                     /gene="hsdR"
                     /locus_tag="ACL3R8_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR1314343.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKAHRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9803..11320
                     /locus_tag="ACL3R8_001487"
     CDS             9803..11320
                     /locus_tag="ACL3R8_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR1314344.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINAIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILPLDQGFKNRQAQTKQSPSSFIEII"
     gene            complement(11409..11558)
                     /locus_tag="ACL3R8_001488"
     CDS             complement(11409..11558)
                     /locus_tag="ACL3R8_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR1314345.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFYKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            11523..11642
                     /locus_tag="ACL3R8_001489"
     CDS             11523..11642
                     /locus_tag="ACL3R8_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR1314346.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(11738..13084)
                     /gene="glnA"
                     /locus_tag="ACL3R8_001490"
     CDS             complement(11738..13084)
                     /gene="glnA"
                     /locus_tag="ACL3R8_001490"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR1314347.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(13121..13477)
                     /gene="glnR"
                     /locus_tag="ACL3R8_001491"
     CDS             complement(13121..13477)
                     /gene="glnR"
                     /locus_tag="ACL3R8_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR1314348.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(13554..14081)
                     /locus_tag="ACL3R8_001492"
     CDS             complement(13554..14081)
                     /locus_tag="ACL3R8_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR1314349.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(14217..15413)
                     /gene="pgk"
                     /locus_tag="ACL3R8_001493"
     CDS             complement(14217..15413)
                     /gene="pgk"
                     /locus_tag="ACL3R8_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR1314350.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(15503..20443)
                     /locus_tag="ACL3R8_001494"
     CDS             complement(15503..20443)
                     /locus_tag="ACL3R8_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR1314351.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANPELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDNLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            20736..22367
                     /locus_tag="ACL3R8_001495"
     CDS             20736..22367
                     /locus_tag="ACL3R8_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR1314352.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGFGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTITFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT         6560 a         4677 c         4266 g         7041 t
ORIGIN      
        1 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
       61 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
      121 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
      181 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
      241 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaacta gccacgggct
      301 gctcaaaaca ctgttttgag gttgtagata cgactcacat atatacggca agccgacgct
      361 gacgtggttt gaagagattt tcaaagagta ttattctcca tcaaaggcat ctttaatatg
      421 atcaaagaag ccttttttct ttggatttac tttcaagtca ccagcagccg cgaattcttt
      481 caaggctact ttttggcggt cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta
      541 ttggtcacca actgcaccgc cacgaaggct cggtgccccc ttactacgta ggcggaattt
      601 cttaccagtc tgagttccct ctggaataac caattcaaca tcaccgtgaa cagttggaat
      661 atctactgta tcaccaagag ccgcttggac aaagttgagg ttgagattgt agaagatagt
      721 cgttccttca cgttcaaact tgtcgctagc ttccacagaa actactacat acaagtcacc
      781 ataaggtcca ccgttaaagc ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt
      841 ttccacacca gcagggattt tcacatgtac gctatgagct tgtttctcat gacctgttcc
      901 atgacaggtt gtacatggat atttgatttc ttttccttgg ccgtgacaga catcacaggt
      961 tacttggcga cgcatcatac caagaggagt ctgcgtatcg acgttaatga caccagcgcc
     1021 atgacagcgt ccacaagtga ctggacttgt ccctggctta gcaccagagc cattacatgt
     1081 acgacagcca gcttcacgat gatacttaac ttccttctca gttccgaaga tagcttcttc
     1141 aaaggtcaaa ttgacacgat actggagatc atctccttgg cgaggagcgt ttggattgcg
     1201 cgaagaaccg cctccgccga agaaacttga gaaaatatcc tcaaaaccac cgaagccacc
     1261 tgccccattg aaaccgccga aaccaccatc tccaccaaaa ccaccattgg cgcctgcagc
     1321 accatactgg tcataggcag cacgtttttg gtcgtcactc aaagtctcat aggcttcttg
     1381 aacttccttg tacttgtcct cagcaccagg ctccttgttg atatctgggt gatatttttt
     1441 ggaaagctta cgataagcct ttttgatttc gtctgccgaa gcgtttttgg atacccccag
     1501 acgatcataa aattcagtat tgttcataat tcaagataca aagggcgtca aacggacaca
     1561 gccatctagg agttttgacg acggacgctt atgtcctaga aaaaactatc tttttggcac
     1621 agtccgtagc ccgtgttcag ttacgaacac ccttattcct ttctattgat gttctgaatc
     1681 gaaccaccat ttaggtcgga ttcaattcct ttcttttata tttagtaaga aattctgaaa
     1741 cccgtgttca gttacgaaca ctctttgttc ctttctattg atgagacaaa acccaaacaa
     1801 atgagattcc gtcccttttt atcgaaaaac agaggctggg ttgcaacctc tgcaaataag
     1861 taaattaact ttattttgat tttaaatatc ctataagtac agaaatattt atatattttt
     1921 gtctcttctt agtatttgcc tatataattc caattgatca taagaaatac aactactgtc
     1981 caaatcatac caattatgaa cggtattaca aatttatatg tttgtatttc taatgatatc
     2041 atagctgata ccatcgccga tacaaatgca gacaacaata ctgaagtaac aaaattcctt
     2101 accgcttcat catttttgac acaactatca tgctcagcta atataatttc tctatatata
     2161 gtcaaacatt ctactggaat attatctata aaaccttttg ctgcttcata gttgtcagct
     2221 tgattacaaa aatcattata aacttttcgt gtatttttta gatactcatc atccaataca
     2281 ctcatcttat ttttccgtaa actctccgtc tacgacgtca tcgcctgcgt ttcctgttgc
     2341 ttgtgcgcct tctgctcctt cttgagcttg ttgcgctgct gcggcttgtt cgtagagttt
     2401 cacagcaagg ccttgagctt tttcgttcaa cgcttcaagt ttcgctttca tgtcgtccaa
     2461 gttgttgtct tcttgagctt tcttaaggtc atcaagggca gcttgggcag cgtcacgttc
     2521 tgcgtcgaag cctttacctt cagtttcctt gattgtcttt tcagtcgcaa agattgcttg
     2581 gtctacttca ttacgaaggt ctacttcttc tttacgtttc ttatcagctt cagcgtttgc
     2641 ttctgcatct ttcatcatgc ggtcgatttc ttcgtcagtc aaacctgagt tcgattggat
     2701 gacaatagtt tgttcttttt gagttccaag gtctttggcc ttaacagaca cgataccgtt
     2761 cttgtcgatg tcaaatgtta cttcgatttg aggaattcca cgaggtgcag ctgggatatc
     2821 agtcaattgg aagcgtccaa gagtcttgtt atctgctgcc attgggcgtt caccttgaag
     2881 aacgtggata tcaacggctg gttggttgtc tgctgctgtt gagaagactt gtgatttaga
     2941 tgttgggatt gtagtgttgc gatcgataag ttttgtaaat actccaccca ttgtttcgat
     3001 accaagtgac aatggcgtta catcaagaag gacaacgtcc ttgacatcac cagtaatcac
     3061 accaccttgg atagccgcac ccatagcaac tacttcatca gggtttactg atttgtttgg
     3121 ttctttacca gtttcagctt taacagcttc aacaacggca gggatacgag ttgaaccacc
     3181 aacaaggata acttcgtcga tttctgacaa gctcaaacct gcatctgaaa gggcttgacg
     3241 aactggaact tttgtacgtt caacaaggtc acgagtcaaa tcgtcaaatt tcgcacgagt
     3301 caaagtcatt tccaagtgaa gaggtccagc ctcacctgca gtgataaatg gcaagctgat
     3361 ttgtgttgaa gttacaccag aaaggtcttt cttcgctttt tcagccgcat ctttcaaacg
     3421 ttgcattgcc atcttgtcag tagacaagtc gataccgttt tctttcttga attctgctac
     3481 caagtggtca atgatttttt ggtcaaagtc gtcaccacca agtttgttgt cccctgcagt
     3541 tgacaatacg tcgaagacac cgtcacccaa ttcaaggata gagacgtcga atgtaccacc
     3601 accaaggtca aataccaaga ttttttcttc tttgtcagtc ttgtccaaac cataagcaag
     3661 agctgctgca gttggttcgt taacaatacg ttctacttca agaccagcaa ttttaccagc
     3721 gtcttttgtt gcttgacgtt gagcgtcgtt gaagtaagcc ggaactgtga taacagcttt
     3781 ggttactttc tcaccaaggt agtcttcagc gtagcctttc aagtattgaa ggatcatagc
     3841 tgagatttct tgtggagtgt attcttttcc atttgcagaa actttttcag aagttcccat
     3901 cttagatttg atagagataa ctgtatctgg gtttgtaact gcttgacgtt ttgcagcatc
     3961 accaacgatg atttctccgt ttttgaatga gactacagat ggagttgtgc ggtttccttc
     4021 tgggtttgcg atgattttgc tttcagttcc ttcaagaact gcaactgctg agtttgttgt
     4081 acctaagtca ataccgataa ttttagacat gtgtttttct ccttgttagt taattttcta
     4141 tttttctttt tgatactctt cttaagtggc gacgccgtca gagcttgact tcgtcaatct
     4201 ctttgactaa actttgagcc taaggtctca aaatttgcgc aaatagcacc acggcgaaga
     4261 gtatcgtctt tggttcgctt cgctcactat tacaaagcca aacatatttt atctttcttc
     4321 atagtttatt gtcgtttcgg acaagttttc tattatgtaa attgcgacac gaggagtcga
     4381 aatcgatttt atttcgacga cgagttagta aggaagctag gcaaacgtca tagcgattgc
     4441 cgttttctga cgagttgctt tagctaccgt cagaattgcc gaatcgaaca cgccctaagc
     4501 tctgagtaaa aaagatagat tttcttgtgt tcatcgaaca cttcgtcaat ctcctatttt
     4561 tactgcgagc tttttacgag ctttgtatct tagttataca ccactaccat tgctgggcgt
     4621 aggatgcggt catggagttt gtagcctttt tgaaagactt gggcgatggt atctactggg
     4681 tgttcatcgt ctgctgggag agtttggatg gccatatggt agttatggtc aaattcgcca
     4741 tctgctgcga tttcttcaat tccttcttct ttcaaagcgt gaatcaagct ttcttgcacc
     4801 atcgccaagc ccttcttcac atcatctgtc aaaccttcaa ctgcaagtgc acgctcaagg
     4861 ttgtcaagag atggtaagat tgcttttgcc aagtcctggc tacgataacg ttgcaagttt
     4921 tgacgttctt cattggcacg gcgttggata ttttgcattt ctgcatgagc gcgaagatat
     4981 ttgttttcga actcatctgc acgttcattt gccaagtcca actcagactt ttcaggagtt
     5041 gtttcttcag ctgtttccac aacttcctct tcttgaactt cttctacttc ttcatttttt
     5101 atatcttggg ccatgttcgc ctcctttaat gatttcaatc ttaatgtact tcgtaatgat
     5161 tactgctgag gtagcggtaa aaatctgtca acttcatggt caaaacacgg ttgaccacat
     5221 tgatttgatt gattagctgt tggtaatcca gattaactgg accgataatg gctagaattc
     5281 caactcctcg ataaggaatg aggaacttac tactaatcac tgctaggtca gctaaacagg
     5341 actcttgacc gtctgcaaca cgaacatttt gcatctgatc ctcacgcaac ccctcacgaa
     5401 tctccaaggc caccttttgc ggttggtcaa agaactgata ggctgctaga ttggcaaaat
     5461 tcaagagatg gaccttgccc gccatcacaa tgttttcgtt gaacatttcc ttaaagatgt
     5521 gttcaaagag atcgatgaca ttatccgttg ttgtaaagta acgctggata atctgcggaa
     5581 tctccgtccg aatcttgtag tgaatatcta aaacggtgtg accgaggaaa cgttcctgaa
     5641 tgatgctctt cagtttcagc aaatcctcct gcaagaagtt ccttggaatc agaaactgac
     5701 tagtaaccgt tcgcgactcg tctagggtaa ataccgccaa ggctgtatgt tgccccaaaa
     5761 caacgatatc aaaggctgtc aaacgttgcc tgctcggctc aacatccagt gccactaccg
     5821 tacagccact caggtctgtt agtaagttag cagcctcttg cagaatatcc tccaatttga
     5881 agaattcctg atcaaaggct ttgacaatct catatacctc attttcagcc agccggtcaa
     5941 aatccagtga gtgtttcaca tagtactgaa aaccagcaac acttggcatc cgaccgcttg
     6001 aagtatgagc cttctcaagc aacccttgtt tttctagttc cgccatgtca ttacgaatgg
     6061 ttgcactgct agagttaata gactcttgca aggcttttga tccgacaggt tcgtgcgttt
     6121 tggtaaagat gtcaataatc agatttaaaa tatcctgctg acgctctgta accatctcat
     6181 cactcctctc tgtctgatca attagcactc aatgcatcca agtgctaact catgattcta
     6241 ttatacaccc ttagaagaga atgtcaagac aaaaactcaa aaaattagca ctcttttatc
     6301 aagagtgcta aaaatcaatc tgaagaccta gaaccttgct attcatctac tcggtatttc
     6361 ctttttagtc tgaaataacc ataaattaga taagaaatca gaaaagcata taaaacaaaa
     6421 ataagaaaga aagacataga aagatcctct ctaaacaaac tcatacaaac aacaagacca
     6481 cctgagaaag tagctgtaca ggaacgaagt ctagattgca taacttccca tttgagccct
     6541 ttactcatac agacttgatc ctctggaagt aaatcagaag acgatttacg aagaatcgaa
     6601 caagaaccta ctcctatcaa ttcccaacct ctatctctaa aatcttgcag ttcatgctta
     6661 tactttttta agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg
     6721 gtcaaaatag aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc
     6781 atgtaaatgt tcttcttcct tgtccaaatc aacaatggtg aaaatccgaa attctactct
     6841 gctattcatt gtcttacccc aaaattagaa aacatgcctg gcgttattta ttagataatt
     6901 ctttccactt ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca
     6961 ataaaaccca atctattatg aaaatcaaaa acactttcca actgaaagaa ctacctccag
     7021 tgacaaactt tgagaaaaac ggtagtagag ctaaaaagag aaataaaata ggaagcatcc
     7081 gcattgttaa aatccgtttg gcataaaaaa atctttattt aaacgaaaat attatggcaa
     7141 aatttacgcc agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat
     7201 gtgattattt atttttgaaa aatagatcac cagcccgact gaaagtgctt atagaatgat
     7261 aataagtcgc ctgccgaaaa cagcgaaaaa tagcggtgtt atgcggagat aatctgacgc
     7321 gatgcgaaag tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt
     7381 gatataatag aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga
     7441 atgcggaggg ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga
     7501 tattaaagca aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca
     7561 tatcgcttac gaagaatact tcactgatgg tcgaattgaa gttagaggag ataaggctca
     7621 tcgtaaagaa ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc
     7681 aattgttgag gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga
     7741 atatggagag attttagatg ttccatttgt ttattcttcg aatggtgatg gctttattga
     7801 acacgaccgt atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga
     7861 agaattattt tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat
     7921 ctcaactcca tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat
     7981 agctatcaac cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat
     8041 ggcaacagga acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc
     8101 tggtttggct aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat
     8161 ggctgaagac tttaggccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac
     8221 tgctcctgaa aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg
     8281 tgaagatgga actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt
     8341 aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga
     8401 ttatttcagt tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc
     8461 ttccaatacg gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga
     8521 ggatggtttt ttggctccat atcgtgttat gagagttaat ttagatgtag atgtggatgg
     8581 ttatcgtcca gaaactggaa aagttgatgc taacggacaa ttaatagaag ataggtacta
     8641 cggcaggaaa gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa
     8701 gtttgtttct gattatatga agcaaaacaa tgcacgattt gataaaacaa ttgttttttg
     8761 tgttgatatt gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt
     8821 agtccaagaa gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc
     8881 tcaactggat aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa
     8941 attattaacg acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat
     9001 ccaatccatg actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa
     9061 ggggaaagaa ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc
     9121 tgattttgat ggtgatccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc
     9181 tacgcccggt ttcgtaagtg aggaaggtga cccagtagaa aaatatatcg ttacagacaa
     9241 gcaggttacc attcttaatt ctactgttca agtattggat gaaaacggga aactgattac
     9301 cgaaagcctg accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga
     9361 ttttatcaca gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa
     9421 aaaaggagtt tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga
     9481 tgattttgat ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg
     9541 tatcaataag ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt
     9601 tttggaaatt ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga
     9661 aacattaaaa cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta
     9721 ttttggagat aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac
     9781 agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat
     9841 cactcgaaac gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt
     9901 attattctta aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta
     9961 tgagtcaatt atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga
    10021 acgggtattg acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt
    10081 gaaagagctt gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt
    10141 tgaagatgcg aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgctat
    10201 tgatgaagtt gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa
    10261 aattcttaaa gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc
    10321 gactgatttt attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc
    10381 ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac
    10441 tagtgaagat accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc
    10501 tcatctttta gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca
    10561 tggaaatact ttggagaaaa atgttcgtga atatacgaat gatgaaaaat ttgacattat
    10621 tatgatgaat ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc
    10681 agaattacgg agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa
    10741 agaaaatggt cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa
    10801 aactcgcttg aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc
    10861 tcatagtgtc tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac
    10921 aaagaaaaca gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt
    10981 ctcgaaaact aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa
    11041 tcgtgaagag attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt
    11101 ggctgagttg aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt
    11161 aaatcccttt gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat
    11221 tgataatgta ttagctgata ttcttccgct cgatcaggga ttcaaaaatc gacaagcaca
    11281 aacaaaacag tcgccatcat catttattga gataatatag tagattgaaa taagatgtaa
    11341 acaaatcgat taggaaagtt aaattagttt ctagaaattt ttagcagatg tagtgtacta
    11401 ttctagtctc aatttactat ggcttcaaat atatctttcg aaaaaatatt tacagatgtg
    11461 taattttgaa gcttgtaaaa gttagtaaac ttgtagattt cgatttgaag taacttgttt
    11521 tcttgcccga tattgttttt gaaattgaat ttttccatag tgactccttg attttcttct
    11581 acacgtctga tgataaatct aattcgcaaa agagtcaaga ggatttttcg aaaaataaat
    11641 agcgaccgaa atcgctattt taagggttat aggtatttga tggcttagac tgctgtgtga
    11701 ctgtttaccc acaggcaatc tttcttctat attagtatta gtaaaggtct aaataattat
    11761 caatttccca ttgtgaaacg aaggttgcat aacttgccca ttcgattcgt ttggcttcaa
    11821 ggaagctagt gtagatgtga tctccgagag cagctttaac cacttcatct tctgtcaaag
    11881 ctttcaaagc gttgtgaaga gttgatggaa ggtctgtaat accagcttcc ttgcgctctt
    11941 ctgctgtcat gatgtagata ttttcttcga taggagctgg tgcttcgatt ttattttcaa
    12001 taccatacaa accaacttcc aaaagaacag ccatagcaac gtaagggttc gccattggat
    12061 ccactgaacg caactcaaga cgagttccca taccacgtga agcaggtacg cgcacaagtg
    12121 gcgaacggtt acgaccagcc caagcaatgt aaacaggcgc ttcataacct ggaaccaaac
    12181 gtttgtatga gttaactgtt gggttcatga tggcagtata gttgtaagca tgcttgatca
    12241 aaccgcctag gaaatggtaa gctgtttctg acaactgcat tccttttgga tcatttggat
    12301 caaagaaggc gttatttcct tctgcatcaa acaaggacat attacagtgc atacctgagc
    12361 cagcaatacc aaattttggc ttcgccataa atgttgcgta aagtccgtgt ttgcgagcaa
    12421 tggttttaac aacaagttta aagatttgaa tcttatcaca agcacggaga acttcatcgt
    12481 acttaaagtc aatctcatgc tgtccaaccg caacctcgtg gtgactcgct tctacttcaa
    12541 atcccatttt ggtcaagaca ttcacaatct cacgacgtgt gttgtccgca aggtcagtag
    12601 gtgccaaatc aaagtagcca cccttgtcat tcacttcaag tgttgggtcc ccattttcat
    12661 ccaacttaaa taggaagaat tctggctctg gaccaaggtt gaaggatttg aatccaactt
    12721 cttccatgtg acgaagagct cgtttcaaat taccacgagg gtcacccgca aatggttcac
    12781 cttctgttgt atagacatca cagatcagac ctgcaacact tccattttca tctccccaag
    12841 ggaagactgt ccatgtatcc aagtccgggt acaagtacat atccgactca ttgatacgta
    12901 caaaaccttc aatagaagat ccatcaaaca taaccttgtt cgataagacc ttatctaact
    12961 gttcatctgt agcaggaatt tcgacgtttt tcatggttcc caaaatatct gagaacataa
    13021 gacgaataaa ggtaacattt ttttccttga cttcacgacg aatatctgca gctgtgattg
    13081 gcataagttt tctccttaat ctatgactac ttgcggttgc ctaaccgcga ccaaaaggtg
    13141 actgtactga agcaaaacgc ccctgttgga ggagttcatt gtgaagtgca cgacgtactt
    13201 cagtctgact aaccgctttc ttggatttcg cttcacgttc agcatatttt ttcttaatgg
    13261 cagcgatatt ataaccttca gagatataat ctttgatttc aagcagacga tccatgtcat
    13321 tcaaggaata catgcgacga tttccttcgt ttcgatcggg cttgatcaac tcttgatctt
    13381 cataataacg aatctgacgc gccgataaat cggtcaactt cataacactg ccgataggaa
    13441 aaacagccat atttcggcga aattcttttt ccttcattta caatttcctt ctttctgtct
    13501 attatagtct aaaaaaagac aaacgtcaat tgataatgtt ataaaatgta acattatttt
    13561 tcttttttct ctaaaaagag acgaatacga tcaatatcgt aatttacaat aattgcgaca
    13621 aaaactccca taaacgtttc tgatacacgc acaaacacgt acgaaattgt ctcaccactt
    13681 ggaattgata gggtaatgat taacatagct gctacaccac caataacccc tgctttgtta
    13741 ttcatggcta catttgtcat aatggttaac atggtgcaga ttggaacaac taccaaggtc
    13801 acccaaaagg cttcgtggaa aaaggtattt aataagaaga agaccaaggc atagagtcca
    13861 ccgatactat ttcctagaat acgcgaagtc ccaaaatgaa cactcttatc aaaactctcc
    13921 ctcaggctaa aaacggctgt caaagcacca atttgaagac ctttccagcc aaaaaagcca
    13981 aaaatcaaga gaactagaaa aacagcaata cctgttttaa aggttcgcat accaagtttg
    14041 aactgggatt tatcgaattt atatttttta aaataactca taatctcaac tttctatttc
    14101 cattttatca taaatcggtg atttttatga gtaatagttg agaggaagcg tttttatttt
    14161 aagcaaaaga aaagaggaac tttcatccct ctcttctttg atttgtttat aaaatcttat
    14221 ttttctgtca aggctgcaag tcctggaaga accttacctt caagaagttc cattgatgct
    14281 ccaccacccg tactaatcca tgagaacttg tctgcacggc caaggttaat cgctgcggca
    14341 gctgagtcac caccaccgat gattgattta actcctggtt gtttcacgat agcgtccatc
    14401 acaccgattg taccagcttg gaaatctggg ttttcaaata cacccatagg tccgttccat
    14461 acaactgttt tggcaccagt caaagcttcg tcaaatttgg cgatagattt tggaccgatg
    14521 tcaagaccaa ggaagccttc agaaactgct tcaccttcag tgtcacgcac ttcagtgtaa
    14581 ccagcaaatg cgttagcttc ttttgagtca actggcaaga tcaatttacc atttgctttt
    14641 tcaagaagag ctttcgcaac atccaatttg tcttcttcta caagtgagtt accgatttcg
    14701 ataccttgtg ctttgtagaa tgtgtaagtc atcccaccac cgataaggac tttatcagct
    14761 ttttcaagca agttttcgat aacaccgatc ttgtctgaaa cttttgaacc accaaggata
    14821 gccacgaatg gacgttctgg agtttcaact gcttcttgga tgtaggcaat ttcgttttca
    14881 agaaggaaac cagcaactgc tttttcaacg tttgctgaga taccaacgtt agatgcgtgt
    14941 gcacggtgag ctgtaccgaa tgcatcgttt acgaagatac catctccaag tgatgcccag
    15001 tatttaccaa gttcaggatc gtttttagat tctttcttgc cgtcaacatc ttcgtaacga
    15061 gtgttttcaa ccaagagaac ttgtccatct tcaagagcgt tgattgccgc ttccaattca
    15121 gcaccacgag tgacacctgg gaaaacaaca tcttgaccaa gttttgctgc caagtctgct
    15181 gctacaggag caagtgattt accagcttta tcagcttctt ctttcacacg tccaaggtga
    15241 gagaaaagaa ttgcacgtcc accttgttcg atgatgtact taatagttgg aagagctgct
    15301 gtgatacggt tatcgttagt gattacgcca tctttcaatg gtacgttgaa gtcaacacga
    15361 acgaggactt ttttaccttt caagtcaacg tctttaacag taagttttgc catgttacaa
    15421 aaactccttt atttatttta ttcgaaacta ttatatcaca ctttggaaat ataaggaaag
    15481 atttcacaag atttttcgat atttaatctt tatcttctct tttccgtctc aaggtcaagg
    15541 ctaaactagc aagaccgagg ctggctaagc ctgctattag ggcttcatta gcatcagctg
    15601 ttcctgtatt tggcaattgt ttgcttgctt cttctgattt aactgctgta ttttgagctg
    15661 gtttttcctg tgtagctact actgctggta ctgtttttac ttttgttcca atttcaacaa
    15721 tttctggaat cgcttcttgg atgacttctg ttgaacgaag acgacgctga ccgttttcat
    15781 caacttcaaa gacatgtctt aacagtccat ctcgtccctg tataatgact cgttgttccc
    15841 caactagcat ctcagcattt tcatgctctt gacgatgaaa ggcaaccttt tcctcttgaa
    15901 cttccaattt aggagccttt tgttgatcag aagccggttg ataagtaggt tttggaagga
    15961 ctttgttttg tggtgctggt ttagcaggtt gtggtttttc agcagattca taaacaaagg
    16021 cataatgagt aaagtgaggt gctgtaaaga taacatgact atccgtttgt tcaaaagcca
    16081 attctactgc ctctttgcct tcaggtaaga aaaatacttt cttaactttc ttatcttttt
    16141 caattgggat tttcacaata gaagcataag agagatcaac atcttgacct ttttcatcca
    16201 aaccttctat ttcaaagaca tgagcatctt ctccagcaaa gtatttcttc tcttcagcac
    16261 ttgcttgaac acgctctact ttcaaaccct tgatgacagt cttctcttta tttgagaagt
    16321 gtacttcaac acctgtttta ctatcagaaa agactgctga cttgtcttct ttcaataaag
    16381 caaccagatc ttttagactc tgtttcgctg ttgcaagctc ttctggactc aaatctactt
    16441 tttcaaccaa ggccttgttt ttctcaagaa gcggagctag ggcagaacct gaaggatggt
    16501 ttggtttggc agccaagagt tcttgagcct cacctgttaa gcgatcaagc tctgtctttt
    16561 cttccgtaaa tttctcttga ccattcagag ctttatgagc ttctgtcaat ttattaagtc
    16621 ggtcattgac ttgatcttgg gtgctagttt catggtcttt caacacttgt tcggccgctt
    16681 caattgcttt caagaaggct tcttttactt ctggtgaagc aaagttatag accaccttgt
    16741 tcttagcagc ttcaacttct gctaattttt gtttgaggta ctcatcgttc aatgctgctt
    16801 ttggagatac caaaacatca aagttgactt catgaccttg gtaacgaagc gtcaaggttt
    16861 gacgaccagt cttttgagca tcgtaaccag aaatttcaac tccctcatca gtaaaggaat
    16921 gttcttccat ggtgtcattg ctataagcca ctgcaaagcg tccttcagac aagtctaagt
    16981 tatcaccaac taggtaatct tttttcggtt cctgacttac ttcaattccc aaaatagttt
    17041 tcggacttgc ttcatcttgg ccagtgacag tcactgacaa attagcattt actggttgtc
    17101 ccaaatattg gagagtaaga ttctgttctc ccttatgatg cgtatcaaaa cctgatactg
    17161 atacacctgc gtgagttagg cgaatgagtt cgtcctcagt tcctccttca tactgaactc
    17221 gaagaacacc acctctaagg tccaaatcct ccccttcggc gtagcttgtt ttcttaggtc
    17281 ctgtttctag gctgactgac ttgattcttc tgtcatcttt tggaacggaa actgctagga
    17341 cattactaat ttccttgcct ggcaactggg tacgataata aagaagacca gattgatttg
    17401 tcaaatccaa tggtgcactt gctaggtctc ctccaacttc gctcttcaag gttgcgagcg
    17461 gagtttgaga atttggatta tcataaacgg taatagttgc tccagccggt acatctgcaa
    17521 agccaacttg taccttgtta ttgcctagag aacgggctgc agccttggcc atcggaatat
    17581 tgacactctc agtatcaagc ttttcataca ttttccagtt atagatacga atagccttcc
    17641 atggagttcc attgtcagaa gtgacaacat tcaagcgcca gtcttgagca gtgattggtt
    17701 tatcaagagt gatatctgtc acgtgtgctt tgttaccacg gacttcctta gctagcttcc
    17761 actcaccatc tgcatcttta taataaaggt caaagtcttt agtgttcatc aagccatcgt
    17821 taacagactc accaccagct cctgcatgat ccatgaccca tctaacaaca gtacgtggct
    17881 tggtcaaacg aatatccaca ctaccactca actgagctga agaccattta tctgacaagc
    17941 tagtaatggt accgttcaac ataccttcaa taccttctcc accttcagtc ttagggaaag
    18001 tactatcaat aactgttgca cctggaacga tattttcagc tagtggtttt ggtaggctgg
    18061 tatcttttac agtcataccc caatcaaagg ttgtggttgc agcttctgaa cgaactccat
    18121 ttttaccgac tgctacaacc ttcagttctt gagttgtacc ctgagcactt gctgagcggc
    18181 taacttttgg tagataaata gttgtagaag atgagccagt tagtaatttc cagctgtctc
    18241 catctttttc ataaacttca tagaaatctg catccttgtt gcctttaaat tgcacaactg
    18301 cttccgcttc ttgggcattt ttaagagatt gtttcactac agaaaagctt gtcggcgatt
    18361 gtggctcttg gtgattgtcc gagatagtta attgtccgag gttgaactga taatctttta
    18421 cagcaccttc atgctcaaaa aatagtttga ctgcatagat ggttttacct gctagtgagc
    18481 tgagagcaaa ttcttcattt gtccagttgt cagaaagggt tagctctttc catgcatctg
    18541 catcatcgaa tttgtagtct ggagttgtag agaatgccat ataaacttta gaaccttttc
    18601 ctcccttgtg ggcaacacga agtttggtct tctcagttac ttctaactta gtagaataaa
    18661 gtctcacatc ctgatctgtc ttaccggcta catcaccaga gaatttaagg gaatttccgc
    18721 cattataggc atctgtaaaa tcatattctg cacgaagttt ttcccctgtt gaagtctgcc
    18781 accagcgcca tgttggaaga acacctgata ctgaacgata attccactca gaatccttag
    18841 aaaccttacc atctacgaac cattttttac catgacctgt attaaaagaa gtagtaaaag
    18901 tattacctac cgctggcgta cggtccgcaa ctaggttagc aataccatac caatctttgt
    18961 cacctggttt ttggccagta gggtctcctt gataacctgt aaagaagata tcttcatttt
    19021 tatgataatc ttcaccagtt tttcctaaac ttgtaatggt atctggggca aataaaccaa
    19081 gagaaaggcg caatttccca ttttcgtcta aaatgtcatt ccacttaacc tttgtcttgt
    19141 aggaaccacc ctgttgcaat tccaaacctg caaatacatc ataaggatta cgaccaatcc
    19201 agttggcagt tgcaatagtg taatcatttt tagccttatc ccagttaaag ttagcaaaga
    19261 agttatctgc cggaacctta tctccttctg gttgcatgaa ttggtagttg tattctccca
    19321 aaccatcttg atgataacgt ccatagttat aggtcatggc atcgtaccaa gaatacttga
    19381 ttggatggtt taccttagca gcatattcct tgctatagag cataaactgg cgcatctttt
    19441 ctccaagagg tttaaccaaa tctccagttg tttcttggtt gatgaaatag ccatcatagc
    19501 cataatactt ggccatgtct accaatttac gggcaattgg gaagctacca tctgcgtctt
    19561 gcttcaaagc ttcagcaaat ctttcttgat ctgcaatact attagaccag ttgaagaaga
    19621 gtgtaccgta tacaggaacc ccgttacggt gacctgcatc aataacgtca ggagttggta
    19681 cgagaccttc ccagaagacc attgaatcta gatattgcca atagtcaaaa gcataggcct
    19741 tgaactcttc tccaccaaca gaagcatggt cttttgcttt agaattggtg tttgataagg
    19801 cttgaacttt tgcttccttg ctagcttttt cattgactaa atgacctgtc cgacgtgaag
    19861 cgaggacaac agatccgcgg ttaatagcat catcttcacg agcacctggt tcccatttta
    19921 acaattcttc ccaagaatta aatttgattt cctttggttt taatgttttt tctgtatttt
    19981 tagggacatc tggctggact tctttttcag tcttattagc ttctgctgct ggtttagact
    20041 catccccttg gttagttgct tcgggctttg cttctgtttc cttgtcagac ttaggttttg
    20101 cttctgcaga tggtgtttct gcaaccacct cacttgcttt ttcctctggt ttagctgcgc
    20161 tagctgcttc tgcagtttca gatgctatcg ctactccttc tgccttttct agcttgtttt
    20221 ctctagcatg ttccccttca ttctgcttat cagcttcatt ggtcgaatgc tcactctctc
    20281 ctgaaacaag ctctggatta gctccgctat tttcaggaac tgcagtttct tcagccaagg
    20341 ctggaccagc aaataaaaca gcaccaatca tcagcgagca ggctcctact gataacttac
    20401 gaatactgta acgacaacgt ctttcaaaaa atggattctt cattttctcc tcctaaaaga
    20461 ttgattttgt tgttttcaag aaagcgcttt atattctgta gttttttatc aaactctaga
    20521 accatgataa tcacattttt atcctaaaac atttttagac aaaaaacaat aactgtttgc
    20581 acaaatctaa aataaggtta aaaactctta aaaataatac acttatcaat tataattttc
    20641 ttttacaaac ttgacattaa cacttgttag atttactttt atcctttaaa atagaatagg
    20701 agatattccg cgattatttt tcggaggaaa aagaaatgtc cattaattgg caggaaattt
    20761 tatttcactt tttaggtggt ctggggctat tcttatatag catcaagacc atgggagacg
    20821 gtttgcaaca agctgctgga gatcgccttc gtttttacat tgacaaatat actagtaatc
    20881 ctttctttgg agttctggtt ggtattggga tgactgctct aattcagtct agttctggtg
    20941 taacagttat cacagtcggc ctggtcagtg ccggtctctt aaccttacgt caggctatcg
    21001 ggattgtcat gggtgctaat attgggacaa ctgtcacatc ctttctcatc ggttttaaat
    21061 taggtaacta tgccctacct atgctcttta tcggtgccgt ctgtctcttt tttacaaaaa
    21121 atcggacagt caataatatc ggacgcatcc tctttggttt cggtggtatc ttttttgccc
    21181 tcaatctcat gagcggcgca atggctccac tcaaggattt acaggtcttt aaggactata
    21241 tgattgagct aagtaagaat cctgttttgg gtgtctttgt cggtaccggc ttgaccttgc
    21301 taattcaagc ttcttcggct accattggga ttttacaaaa cctctacgcc ggcaatctaa
    21361 ttgacctaca gggagctttg ccagttctat ttggtgacaa tatcgggaca accattacag
    21421 ccatcattgc ctctttaggg gctaatattg cagctaaacg ggtagcagga gctcatgttg
    21481 ccttcaacgt tatcggaaca gtcgtctgcg ttatttttct agttcctttt actgtcctga
    21541 ttcattggtt tgaagctacg ctaaatctag caccggaaat gaccatcacc tttgctcacg
    21601 gaacctttaa tattaccaac accattgtcc aatttccatt tatcggagct ctggcttact
    21661 ttgtaaccaa gattattcct ggagaggacg aggttgtcaa atacgaaccc ttatatcttg
    21721 atgaacattt catcaaacag gccccatcta tcgctctagg aaatgctaag aaagagctct
    21781 tgcacttagg aaactacgct gctaaagcct ttgacctttc ctataagtac atcattgatt
    21841 tggatgaaaa agttgctgaa aaagggcata aaaccgaaga agcaattaac accatcgatg
    21901 agcaattaac acgttatctc attgcccttt caagcgaagc tctcagccaa aaagaaagtg
    21961 aagtgcttac caatatcctt gattcctccc gtgatttgga acggattgga gaccacacgg
    22021 aggctctact caatctgact gactatcttc aacggaaaaa tgttgaattt tctgatgccg
    22081 ccttgaaaga attagaggaa gtttaccgcc aaactagtga ctttatcaaa gatgctctgg
    22141 atagtgtgga aaacaatgat attgaaaaag cacgcagtct tgtagaacgt catgaagcaa
    22201 tcaataagat agaacgtgtt ctcagaaaaa cccacatcaa acgcctcaac aaaggcgaat
    22261 gttcaacaca agctggggtc aactttatcg acatcatctc acactacact cgtgtatcag
    22321 accacgctat gaaccttgct gaaaaggttt ttgcagaaca aatctaagaa ccaagaagct
    22381 atccatcata attggatggc tttttacttt ttcctaagca agactaggct gaatgaaact
    22441 gaaagagtat tctgcagata tatagtatat tgaaactaga atagtacacc tctatttcta
    22501 aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcc
//
LOCUS       DBEJZJ010000030        22503 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000030 DBEJZJ010000000
VERSION     DBEJZJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.30"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(74..424)
                     /gene="rbfA"
                     /locus_tag="ACL3R8_001496"
     CDS             complement(74..424)
                     /gene="rbfA"
                     /locus_tag="ACL3R8_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR1314353.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(675..3440)
                     /gene="infB"
                     /locus_tag="ACL3R8_001497"
     CDS             complement(675..3440)
                     /gene="infB"
                     /locus_tag="ACL3R8_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR1314354.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            complement(3457..3756)
                     /locus_tag="ACL3R8_001498"
     CDS             complement(3457..3756)
                     /locus_tag="ACL3R8_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR1314355.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIEDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(3749..4042)
                     /locus_tag="ACL3R8_001499"
     CDS             complement(3749..4042)
                     /locus_tag="ACL3R8_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR1314356.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(4064..5200)
                     /gene="nusA"
                     /locus_tag="ACL3R8_001500"
     CDS             complement(4064..5200)
                     /gene="nusA"
                     /locus_tag="ACL3R8_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR1314357.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(5244..5723)
                     /gene="rimP"
                     /locus_tag="ACL3R8_001501"
     CDS             complement(5244..5723)
                     /gene="rimP"
                     /locus_tag="ACL3R8_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR1314358.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(5849..6484)
                     /gene="trmB"
                     /locus_tag="ACL3R8_001502"
     CDS             complement(5849..6484)
                     /gene="trmB"
                     /locus_tag="ACL3R8_001502"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR1314359.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(6481..7275)
                     /gene="ccrZ"
                     /locus_tag="ACL3R8_001503"
     CDS             complement(6481..7275)
                     /gene="ccrZ"
                     /locus_tag="ACL3R8_001503"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR1314360.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(7437..8048)
                     /locus_tag="ACL3R8_001504"
     CDS             complement(7437..8048)
                     /locus_tag="ACL3R8_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1314361.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(8199..8432)
                     /gene="blpZ"
                     /locus_tag="ACL3R8_001505"
     CDS             complement(8199..8432)
                     /gene="blpZ"
                     /locus_tag="ACL3R8_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR1314362.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(8474..9163)
                     /locus_tag="ACL3R8_001506"
     CDS             complement(8474..9163)
                     /locus_tag="ACL3R8_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1314363.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRELLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(9215..9598)
                     /locus_tag="ACL3R8_001507"
     CDS             complement(9215..9598)
                     /locus_tag="ACL3R8_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR1314364.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(10227..10546)
                     /locus_tag="ACL3R8_001508"
                     /pseudo
     CDS             complement(10227..10546)
                     /locus_tag="ACL3R8_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(10608..10769)
                     /locus_tag="ACL3R8_001509"
     CDS             complement(10608..10769)
                     /locus_tag="ACL3R8_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314365.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            complement(11066..11185)
                     /locus_tag="ACL3R8_001510"
     CDS             complement(11066..11185)
                     /locus_tag="ACL3R8_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR1314366.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(11188..11418)
                     /gene="blpU"
                     /locus_tag="ACL3R8_001511"
     CDS             complement(11188..11418)
                     /gene="blpU"
                     /locus_tag="ACL3R8_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR1314367.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(11487..11756)
                     /gene="blpJ"
                     /locus_tag="ACL3R8_001512"
     CDS             complement(11487..11756)
                     /gene="blpJ"
                     /locus_tag="ACL3R8_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR1314368.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(12223..12420)
                     /gene="blpI"
                     /locus_tag="ACL3R8_001513"
     CDS             complement(12223..12420)
                     /gene="blpI"
                     /locus_tag="ACL3R8_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR1314369.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            12710..13297
                     /locus_tag="ACL3R8_001514"
     CDS             12710..13297
                     /locus_tag="ACL3R8_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR1314370.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            13224..14867
                     /locus_tag="ACL3R8_001515"
     CDS             13224..14867
                     /locus_tag="ACL3R8_001515"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR1314371.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            14878..16239
                     /locus_tag="ACL3R8_001516"
     CDS             14878..16239
                     /locus_tag="ACL3R8_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR1314372.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANYLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            16296..16451
                     /gene="blpC"
                     /locus_tag="ACL3R8_001517"
     CDS             16296..16451
                     /gene="blpC"
                     /locus_tag="ACL3R8_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR1314373.1"
                     /translation="MDKKQNLASFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(16496..17836)
                     /locus_tag="ACL3R8_001518"
     CDS             complement(16496..17836)
                     /locus_tag="ACL3R8_001518"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1314374.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(17850..18587)
                     /locus_tag="ACL3R8_001519"
     CDS             complement(17850..18587)
                     /locus_tag="ACL3R8_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1314375.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETDLLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(18592..18930)
                     /locus_tag="ACL3R8_001520"
     CDS             complement(18592..18930)
                     /locus_tag="ACL3R8_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1314376.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNI
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            19206..19535
                     /locus_tag="ACL3R8_001521"
     CDS             19206..19535
                     /locus_tag="ACL3R8_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR1314377.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(19703..20752)
                     /locus_tag="ACL3R8_001522"
     CDS             complement(19703..20752)
                     /locus_tag="ACL3R8_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314378.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(20749..21480)
                     /locus_tag="ACL3R8_001523"
     CDS             complement(20749..21480)
                     /locus_tag="ACL3R8_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314379.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            21548..21958
                     /locus_tag="ACL3R8_001524"
     CDS             21548..21958
                     /locus_tag="ACL3R8_001524"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR1314380.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            21968..22255
                     /locus_tag="ACL3R8_001525"
     CDS             21968..22255
                     /locus_tag="ACL3R8_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314381.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
BASE COUNT         7040 a         4918 c         3876 g         6669 t
ORIGIN      
        1 tttaaaagaa tatttttcca tttcaaattc aacctatttt cctccaccaa aaaagagggg
       61 caacccctct tctttagttc ttatccagat tgcgtagcat ctcgtcaatc ttgtttccat
      121 actcgatgga ctcgtctttg acgaaggtca aatctgggat tttgtacaat ttcaaattgc
      181 gaccaagttc acgtttgatg gtaccagttg ctttttcaag cccgatttgg gctttttggt
      241 tatccgaagc aaggttactc aaaatggtgt aataaacctt ggcaacagac aagtcaccca
      301 gcatctgaac atctgtgatg gtcacacctt ggacacgtgg atcacggact ttcttttgca
      361 aaatctcatt gacttcacgc ttgatttcca tgcccacacg atctgtacgg aaatgatttg
      421 ccatgatatt cctttctcta ctttgaacca aaagctaggc cagcagacct agctatttta
      481 aacttcttga ttttcagttt aaattgaaac gaagttcaat ttgaagtcat ctgcttcttt
      541 cgccgtggtg aaagtgatgg aactgattta tcagtcccat cacaggggat ttttgagacc
      601 ctaggctcaa aaataagcaa tgaaaccatc ggtttgcttg cgtccctcac cacctaagaa
      661 aggagcaaaa aatcttatct cttgatttct tccatgacat acgcctcaat cacatcatcc
      721 atcttaatat cattgtagcc gtcgatcatc aatccacctt cacggccgtt tgtaacttcc
      781 ttaacgtcgt ctttatagtg tttcaagctt gcgagttcac catcatagat aacgacacca
      841 tcacggataa cacggacttt agagtcacgg gcaaccttac cgttgataac cataaatcca
      901 ccgatagttc ccactttaga caccttgaag gtttcacgga taaccgcttc accaataact
      961 ttttcttcaa attctggatc aagcatccct ttcatagctt cttccatctc ttcgataacc
     1021 ttgtagataa tgctgtgaag acggatttcc acatcgtcag cttctgcttg ttgacgagct
     1081 tgtggtgtag ggcgtacgtt gaaaccaacg ataaaggcat ttgaagcttc ggcaagggtc
     1141 acgtctgatt cgttgatagc accgaccgct gagtggacga tagtcacttt gacaccttcc
     1201 acgtcaatct tttgaagtga ggcagaaagg gcttcaacag aaccttgtac atcagccttg
     1261 atgataacat taacagattt gagttcccca gctttaaggg tatcaaagag gttttcaagg
     1321 ctaacacgtt gggtagcttg acgttgtttc atgagggcac gtttggcacg ctcttcacct
     1381 gctgcacgcg cagatttttc atcctcgtaa acggcaaagt ggtcacccgc catcggtgct
     1441 tcgttcaaac ctgtgataga gactggtgtt gatggtccag caactttaac acgacgacca
     1501 aggtcgttgg tcatagcacg gacacgaccg aaggtatttc cgacaacgat tgggtcttga
     1561 acattcaagg taccttgttg tacaagaagg gttgcgaccg caccttttcc tttatccaag
     1621 cgcgcttcga taaccgtacc gattgcacgc actgttgggt ctgccttgag ttcttggatt
     1681 tcagctacaa gaaggactgt ttccaacaat tcttcgatat tttggttgaa tttagctgag
     1741 atttcaacaa attcagaatc tccaccccaa gcggttgaca tcacaccatg ctctgccaat
     1801 tcaccgataa cgcgttctgg gttagcacct ggtttatcaa tcttgttaat ggctacgatg
     1861 attggaacgt tagctgcttt tgagtggttg atggcttcaa tagtctgagg cataaccccg
     1921 tcatctgccg ctacgaccaa gatcgtaata tcggtaacag aagcaccacg cgcacgcatt
     1981 gatgtaaagg ccgcgtgtcc tggtgtatca aggaaggtaa tcttcttacc attttccacg
     2041 atttggtagg caccgatatg ctgagtaata ccacctgctt cacctgtcgc aacacgtgag
     2101 ttacgaagag tatccaaaag ggttgtttta ccgtggtcaa cgtgtcccat gatagtaaca
     2161 actggtggac gctcaaccaa ttcatcttca ttgagataac catcttcgac aaagaaacgt
     2221 tcgatgtcag cattatccac ttcaaccttt tgtttggctt cgataccgta atccaccatg
     2281 aggagttcaa ttgtttcccc atccaaggat tggttttgtg tggccatgac acccatcatg
     2341 aaaagtttct taacgatttc agctggttca cgtttgatac gttttgcgat ttccgcaacg
     2401 gtcataccat ctgtatattc aaattctgtt ggcaattcat ggaatttacg ctccgtaaca
     2461 ggttttggag tctgattacg gttgttcttg ttattgcctt ttttgttctt tttgttgtta
     2521 ttccagttac tattcttttg atttctcact tgattttgac tacttcgatt cttttgttgt
     2581 tttctaggac catcttcttc atgatcataa tcgtcacgat ttttgtctgg tcgagcttgt
     2641 tttttacgac gtgtatccac tgcaggttct tttttctcag ggacgacttc aaccactgct
     2701 tgaacttgct gtgcttgttc agctaactta gccgcttctt caaagatttc ctctggttcc
     2761 ttgcgtttgt tagcttgagc caaggcttct ttagcagcct gatactgctt gaagcgttcc
     2821 tcacttgaac gagcgtactc tgcattttgc tctgctttta gggctgctgc acgggcttta
     2881 aagtcaatac gtggagccgc ttgatttgaa cgtttatcct cttgctgacg gcgctcattt
     2941 ctacgttttt gctgaccttg ctgcttctta gcttggtcat taaagcgacg attgtcgcgg
     3001 ttgctttgac cttgttttcc accattacgg ccgtcgtttt tctgacggtt tccgttttgt
     3061 tgttggtcac ggttattgcc cttattttgc ttgcgtcgct ctgcctgctc tttagcacgt
     3121 gcttcacgct cagccttgaa attacgactt tgcggtttag ccgctacttt ttctgttttc
     3181 ggagcgactg gctcagctgg tttagctggc tcagattttt cggctttctt ttctgcactt
     3241 acttttggtg ctgcaggttt tgcttctact ttcggagcag ctgcaggctt aaagctggca
     3301 gcaatttttg cagcgacagc ttcttccaca cttgatgagt ggcttttcac atccaagccc
     3361 aactcttttg cacgcgctac aacttcttta ctttcttttc caagttcttt tgcgatttcg
     3421 tacaatcttt tcttagacaa atcatgtcct cctcttctat tccataagag acctcatttt
     3481 ctttgtaaat ccagcatctg ttacagccaa aacctttctc gatttcccga ctgctatgct
     3541 taattccagt gttgaaaaca cggttacaat ttctacttga taataatgac ttttatcttc
     3601 aatcttcttg gtcagattgg gtccagcatc atgagctaga aagaccaact tggccttgcc
     3661 gtcttgaatg gccttgacca ccaattcttc acccgatatg atgcgccctg ctcgctgagc
     3721 aagccccaag agattactta tcttttgctt attcaagtcc caactctctt cttttcactt
     3781 tgtgatccac ataagcgatc aactcgtcat aaaagctttc ttccacttcc atgctaaagc
     3841 tgcggttaaa gaccttcttc tttttcgcct ctagggcttc tgcattgtct agtttgatat
     3901 aagcgccgcg gccattggcc ttgcccgtag gatcaataaa gacttgtcct tccttgttct
     3961 tgacaatgcg gagcaaatca cgcttatcaa tcacttcgtt agacacaaca gacttgcgca
     4021 aagggatttt tcttgttttc atctttccct cctctagcag cttttattct tctacagtat
     4081 cgttttctac ttccaactct actgaagcag cgtcttccat ggcttcaaat tcgctagcag
     4141 acttgatatc gatacggtaa ccagtcaagt gagccgccaa gcgcacgttt tgtccacgac
     4201 gaccaatggc aagagaaagc ttgttatctg gaacaaccac caaggcacgt ttgctgtcgt
     4261 tttcatcaaa gataacttgg tcaacctcag caggagcgat ggcattgtag ataaattcag
     4321 ctggatctgc tacccactcg ataacatcga tattttcttc gattggtacc atgcggtcat
     4381 ttttagcatc gtaacgagct gggtggaatt tgctagtaat cttcttgata ttagcaccac
     4441 cacgtccaac gattgtaccg atagcatcca cgtttggatt gtggctacga acagcaacct
     4501 tcgtacggtc acctgcttca cgagccacgc tcatgatttc aacagttcca tcataaactt
     4561 ctggaatttc ttgctccatc aaacgtttga tcatttctgg atggctacgg ctaacaaaga
     4621 cgttcacacc acgagggttg tcttcaacct tgtaaacata aacttcgata cgatcatgag
     4681 aagcaaaaac ttctccagga atttggtctt gttttgacaa ttgggcttcg atgctaccaa
     4741 ggttgacata gataaagcgg ttgtcaaagc gttctactgt accagacatg atttcttgct
     4801 catgttcttt gtaagtattg taagtgatgg cacgtgtttg cttgcgcatt ttttccatga
     4861 tggtttgttt ggcagattgg gctgctacac gaccaaactc agctggtgct tcttcaaact
     4921 tgattttgtc tccaagttca taagctgaat taatggcaag agcatctttc aagctgattt
     4981 ccaaacggct atcaaatact tcatcaacaa cttcacggac agtataaact gtaaagtcac
     5041 ctgttttttc gttgaagtca atagctacgc tgtctgactg accatagcgt ctgcgataag
     5101 cggaacgaag cgactctact actgcgtcga tgatatcttc ttttttgatt cccttgtctt
     5161 cttccaaaat gcggaaggcc tctagcattt ctttactcat gttttcttca cttttgaatc
     5221 ctcaaaagct atcctttctt tttctataat ttaactgcta aacgtgcttt tgatactaaa
     5281 ctgtatggaa tttggacggt tttcttacgc gtcttgtcca tatattccat agtcaactcg
     5341 tcctcttcga aggccaacaa ggttccttca aagacctttt gcttatcgat ggcttggtag
     5401 agcccgacat ggatgtattt tccaaccgct ccagcgacgg catccttggt tttcaaagga
     5461 cgttccaaac ctggactggt aatttctagg aaatattgtt ctgggaaggg atctggcttg
     5521 atggtgtcta ggacaggact gatcatttct gtcaagtctg ccgtgtcgtt caaggtaatt
     5581 ccttcgggtt tatctacaaa aatactgaga atcatgtcac tgccaatctt tccatactcg
     5641 atatccacga gttcaaaagg agcttctatg acaggttcta caacttctct gactaattct
     5701 acgattgttg cgattgcgtc cacctcctca taagcaagag gcgaagatat ttccccgcct
     5761 cacttttcat attcttacta tcagtatagc acgtttgcca acttatgtaa agcaaaagca
     5821 cttgtacagc ctaattttag gctatctctt aaaattctgc ctcaactcgg tagataactt
     5881 gccccttgtt tgagaatttt tgctcgtatt ctgtcatgac attgccttca aaatcactgg
     5941 catgcaaatc tagccagaca ccattgagtt tcatgccata ttgagaaaag ctcactaaac
     6001 tgtactcaaa caagccacgg ttatccgtct tgaaatgaat ttctccattt tcaggcaaga
     6061 tacgtttgaa ggtatccaaa aaggtcttgt aggtcaaacg acgcttttca tggcgttttt
     6121 tcggccatgg atctgaaaag ttcagataca agcgatcaat ctcaccgtct tcaaagtagt
     6181 cagtcaagtc agaaccatct acccacaaga gcttgatgtt aggcactcca acttcaagca
     6241 ccttgtccaa agcgtagctc aaaacagact tttgaatatc aatcccgata tagttgatgt
     6301 cagggttttg cttggccata cctgaaacaa aggcaccctt tccacttcca acttccacat
     6361 gaatgggatt atcattgcca aacaagtccc gccattttgc cttggcttcc aagggattga
     6421 ggaccacata ctggggattt gcctctagta attctgttgc ccctttacga tttctaactc
     6481 tcatcttctc tttccatact tgtctcggaa atgacgcaaa ccatgaatct cccgattgac
     6541 attttctaaa tcttggttca tataatactt ggaaatctga ctcaaataag acaattgacc
     6601 ataccaatac aatttactta ataccgtttg attgtacttg taaccgtagt aggtcaacca
     6661 ttccttccac tgatgttctg aaatataatg gcagagcata tgggccacat caaacatgcg
     6721 atcggtcaag cgaaccgaat cccaatctac taaataaatc aagccactat ctgtctcaat
     6781 ccaattacta tgtcgtacat ctccatggac aatggtcgca tggtcctctc taaatcctgg
     6841 aatagtctga cgtaaatcag ccatcacttc actgataaaa tgatttttac gcaaagcatc
     6901 tggagccgtt tcttgccaag actgtagtaa atctacaggt gtttccatgg catagcccaa
     6961 acgactcaat tgtgtcatca acggacgtga gcgatgaaga cgggttaaaa tattgacgat
     7021 ttgcttacga ttcatatcat agggggtcaa tatcttgcct gtcaaccatt cttgagcaca
     7081 catatcacgc ccatctgcca aacgacgact ccataataat tgtggagcaa tttgttctct
     7141 agctagacca ggtaggattg gagaggtgtt catttttaca aagatgcgct tcccatcagg
     7201 atagctaccc atataagcct tgccactttt cccaggtatg ggagtcagtg ttagctcatt
     7261 atcacccaaa tccatttctt tcctccgtat aaagtttcct tactattcta ctagtttttg
     7321 gcctattcgt caaccactct aacccgattc tcaaagaaaa gcctctggag tggtttgggt
     7381 tatcattata gaaagaaaaa ggtaagcaca atctcctact taccttttca tgatttttat
     7441 aaataatata agagtggcca actgttgtaa agcatatgga ctagagtaga aacccataag
     7501 ttttggctct ttttataagc aaggcccagc aacaagcccc caagtagata aaaaataaac
     7561 gaagggacat tagaaggtcc atgcatgaaa gaaaagagag aggaagttag cacaagccct
     7621 aaccaagaat tgtcaaaaac cgcaccttga agaagtcctc tgaaaatgag ttcctcctgg
     7681 atggggccaa aaactgaggt agtcaaaatc aaagacaggg aaattcctct gctgacttcc
     7741 gccaagtgtt ggacccctga gccagaagaa acagcgaaga aatgaatata aaccagcgtc
     7801 tcaagtacac ttagaagaaa gattgcaatg aaaagcaaaa gttgtttctt gcttaacatc
     7861 ccaaaagaaa tcatttcaaa ctttctagca taagcaacac tcagcgaggt tacaagaaga
     7921 cttacaagaa tcaatgcaga ttcattttga aaaaaatccc catggttaat cgtataagga
     7981 actataatga caattattag tactaaaaat ccaaaacaca aggcatgaaa tttatcaaaa
     8041 aactccataa aattatcctc ctcaacaaac agacttccta cacgtcattc tttagttcta
     8101 gcctttccaa aacaaaccat tttatactct tcgaaaatca aattcaaacc acgtcaacgt
     8161 cgccttgccg tactcaagta cagcctgcgg ctagtttcct agtttgctct ttgattttca
     8221 ttgagtatta gtaaccaaaa tccgaccaca tagccagccc ctatgaatat agccattaaa
     8281 gctagcatgg aatttaggaa attaaaaacc accgcagata caaaggttag cacaaaaaca
     8341 ttaaaagcaa tggtgtcaga agccaagact agaatatagg gtgtcaaccg atctaaagtt
     8401 ttggaatcta ggaaaaataa gtgtttatac atgatgacct cctctatggc tgaaaagcaa
     8461 gccttttgtt tttttacccc aagaccctat gtagaaaagt gagcaaaaac gggaaggtcg
     8521 ctacaatatt attgatcaca tgcaccgcat aggatggata aatgctcttg gtatagcggg
     8581 tcaaaccagc aaagatgatt ccaactgttg caaagacgaa gatatctaac agactaggca
     8641 ggcttgaaaa atgagggaga gcaaataaaa tagaaggaag aagcaaatca agaccaaatc
     8701 gcgaatgctt aaagaaagca tgttgcagta attctctata gattaactct tccatcagtg
     8761 gaaccagaaa gaacagggct atataaatac ctagctctgc aaagttagtc ccactataac
     8821 caatcaatac agcccaacct tccgcagttg actgaacatg tttagctgtc tgaacgttaa
     8881 aagagatctg gaacactacc actaatactg tcaaaatcga ataccaaagc catttttttc
     8941 ttggaatgcg gaagagataa ccatggcctg tcttaacaag aaccacaatc atgactccaa
     9001 taaaaagtaa actcaagata ttttgaatcc agacgaaatt accaatctgg gaagaaaatt
     9061 gccaataatt ttggacgata agcgtcagct gagaaagacc aaatacgaaa aataagtaag
     9121 agaagactgc acttattttg aatagaagtt gatacttttt catagaaatc ctccctacta
     9181 tgacctcacc ttgtcaggct ctactgctgt aagattaaga agacagtttg ttttttttaa
     9241 ggctaacctg actactagat aatagataca ttaaggcatt aaagacaatg aaaatatgtc
     9301 catagaataa aatcaacctc gcatccaaac caagataaag tttgattatc aaaaagatga
     9361 gcaaaagaat ttgaaaccat aaggtttttc caaaaataaa tttaaagcga tttcgaatat
     9421 ctacttcctt gatttttacc gccacccctt tattagcaag aaggaaaact cctgcttcaa
     9481 acaaaccact gtaaagaaca agccacccaa tagatacgat agagatttgt aaaaatgtcc
     9541 ctaaaagaat atccaacaca ctactcaaga aaataacaaa aaataatctg tatttcatat
     9601 taaatacctc cattcattta tttcactaac aatttaatag agccttctac tcaaatatcc
     9661 tgtcagaaaa ggatagaaag ctacttttta taatacttca agccccacat gagcagaagc
     9721 gtgataaaca agcagagaat acacctatat aaacgattag ttgttgatag aattctgttt
     9781 ctgaaatacc tctatacaaa caaatgacaa acataaaatc tgccaagccg ataaacataa
     9841 gttgattggt tctaggacta accaaatcat catttactta tatttaagag tatctctttt
     9901 atgttagtgt atgttagcac tgaaaagcaa gacagaccaa taatatttaa aatgaacagt
     9961 aacggggtta agtctctaaa aaaattatct actgacacta caagaaatac tatacatatt
    10021 atagtcgaaa ctatcttttt cttatccata attatttact cctttcctaa caaatccagc
    10081 ttatcaatca agagcgattt ttaacataat gtagcagcac ccgttgcaac tttgacaatt
    10141 tcagtatagc actatttgtc aaagtttttc atccaaatct tgaattgtca tcaagacatc
    10201 ttaaattgca aaaactgcat tagcctctac tttttataat acttcaatcc ccaaatgagc
    10261 agaagcatga tggtcaagca gagaatagcg ccaatgtagg caattatttg ttggtaggat
    10321 tctcctgctg tgatccctct atacaaacaa ataatagaca taaagcctgt caagccgata
    10381 aacatgagtt gattggttct aggactaacc aaatcatcat cttcaaactc tcttaatctc
    10441 atttccctag taagataaac agtaaccaaa atagaagtca agttaataac cactaaaaga
    10501 aattggaaaa ctgacgaaat agaaatagat aagtagaaac aagcaaaggc aactgaccca
    10561 ggaacaatct cacaaagaat atgattcttt ttaatcaaga aaatctttca tttcttttct
    10621 ttctttttaa ttaaagaaaa atagatcata accgcaatca tatagactat ggtataaaat
    10681 agctgatacc aagcactctc cctaagcgga tatagaaaga tggacatgat tagatacaga
    10741 acgaaaataa tcagtatttt tttcttcata agatttcctc ctaaatgtgc gatttatctt
    10801 agttgagcaa gaacatttac actgctagta tagcacttat tttgaccttg gatcactcaa
    10861 atcataaatg gtcatcaaaa cctcttgaat tgtaaaaatt aaaaaagcaa gcatgaaaaa
    10921 catactttcc tctttatatt gtattgatac caacttgttt gtagactttt catcctgcta
    10981 tcacatatca ttttgacagg cgaaacaata ttaaagaaac tcccctgtaa attaagctag
    11041 caaatacagg ggagaaattt attttttagg gggtactatc tgtatccttt ttgggaaatt
    11101 ttgaaaatat ttttctaatt aaattatcca tataaggacc aaatatacca actactaaac
    11161 caataataaa acttttaaaa tccataatta ccaccaacat gttgctgcat aggctacacc
    11221 tccaagtata gctccacccg cagcaccagt tgctgcacct tgccatgttc ctgttttaat
    11281 gcctagttga agacctcttg ctgctgctcc tccaacacct gctttggcaa aatctcccca
    11341 attgcatccg ccaccttcaa cgcaagcaag catttcagta tccataacag aaaattgtga
    11401 catcattttt gtatccatga caaatactcc ttttttaaaa aactaaaata aatcagaata
    11461 gaatcctcat aattttacta taagtcttac caacttagtc ccaatttatc accaaccata
    11521 cctcctaagc atgttaatcc acccccaatt gcaccaatgt gtgctccaac aaatgcacca
    11581 gcaagtccag ctactcctaa agtggccaaa cctgctccag ttccaccagt tataattccc
    11641 gtagtgactc ctgtaatcag tgcattttga caatcagtgg agctataccc cccttcaact
    11701 ttcgcaagca tttcagtatc cataacctct aactgtgaca acatttttgt attcatgatg
    11761 aatacctcct ttttattttc aatttgttac caaagtctta aattcaataa acaaatagat
    11821 tttttatagt atctttttga ttttcttaaa aaagtatata cgtctactat cttcttaaaa
    11881 gtagcagtac ctatttttta gtctaagatt tcaataatct tgagtatcta aaatatctta
    11941 atttcgttat tctccttgca ataaaaagtt ttactatact atttattaac ttgcagaaag
    12001 caaaaaatat tagtaaataa tagtttatag ttaagttttt tattcctacc aatccatcaa
    12061 ctaagtaaag catcaacgat tacataaacg attgataata taattaaaat tttgctaact
    12121 atcttattct catcattctt agataacttt gatattttgt aagtaagtaa ataagacagt
    12181 aaattaatag cgataataat actatattta agaatcataa tcttacaaag aggacataat
    12241 tcctgaacct acacaaataa gtgttgctgc tcccccagtt atcggaccag tcgcagcagc
    12301 taatagtact gctccaatac aaccaccgat tgcagatcct aaattgcctc ttcctccact
    12361 aactatttcg agttcttcat tatccataac agaaaattgt tccatcattt ttgtattcat
    12421 gacaaatact ccttttttat ttttgtcttg ttgtaacttt gataagttta gtatatcatc
    12481 gttttttaaa atttttcatc cagatcttga attgtcatcg aaacgtcttg aattagcttt
    12541 tttatttcaa gccacctcta tttcaagcca cctctaaatg tttaaaaaaa ataatttcta
    12601 atcacttttt taccattcag gaagttttaa tgactattca agatttcata aaatatgaac
    12661 ttagttttat gacataatag acctatccac tatatgaaag gaattgccaa tgacttctta
    12721 taaacgtaca tttgttcctc aaatagatgc gagagactgt ggtgtcgctg ccttagcctc
    12781 gattgctaaa ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac
    12841 caataaagaa gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga
    12901 aacaagacct gttcaagcag ataaaacgct ctttgacatg agtgatgtcc cctatccatt
    12961 tatcgttcac gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa
    13021 gaaagactat ctgattattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa
    13081 agaacgcttt ttctatgaat ggactggagt agctattttt ctagctacca aacccagcta
    13141 tcaaccccat aaagataaaa agaatggtct actaagcaag cttccttcct ctgattttca
    13201 aacaaaaatc tctcattgct tacattgttc tctcaagctt attggtcact attatcaata
    13261 taggtggttc ttactatctc caaggaatct tggatgaata cattccaaat cagatgaaat
    13321 caactttagg aatcatctca gttggtctgg ttatcaccta tatcctccaa caagtcatga
    13381 gcttctccag agattatctc ctaaccgttc tgagccagag attaagcatt gatgtgattt
    13441 tatcctatat tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag
    13501 gagaaatcat ttcacggttc acagatgcta actctattat agatgtcttg gcttctacca
    13561 ttctttctct ttttctggat gtttctattc tgattcttgt agggggagtc ttgctggcac
    13621 aaaaccctaa tctcttcctc ctttctcttc tttccattcc tatatacatg ttcatcatct
    13681 tttcttttat gaaacctttt gaaaaaatga accatgatgt catgcaaagt aattctatgg
    13741 ttagctctgc cattatcgaa gatatcaacg ggattgaaac tataaagtcg ctcacgagtg
    13801 aagaaaatcg ctatcaaaat atagacagcg aatttgtaga ttatttggaa aaatccttta
    13861 agctcagtaa atattctatt ttacaaacga gtttaaagca gggaacaaaa ttagttctga
    13921 atatccttat cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt tctatcggtc
    13981 agctgattac ctttaacaca cttttttctt actttacaac tcctatggaa aatattatca
    14041 acctccaaac caaactccaa tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc
    14101 tagtcgaatc tgaatttcaa gttcaagaaa accctgttca ttcacatttt ttgatgggcg
    14161 atattgaatt tgatgacctt tcttataagt atggttttgg acgagatacc ttaacagata
    14221 ttaatctcac gattaaacaa ggagataagg ttagcctagt tggagttagt ggttctggta
    14281 aaacaacttt agccaaaatg attgtcaatt tctttaaacc ctacaaaggg catatttcca
    14341 tcaatcatca ggatattaaa aacattgata aaaaagtctt gcgccgtcat attaattacc
    14401 taccccaaca agcctatatc tttaatggct ctattttgga aaacttaacc ttgggcggta
    14461 atcatatgat tagccaagaa gatattctaa aagcttatga attagctgaa attcgtcaag
    14521 acattgaaag aatgcctatg ggctatcaaa ctcagctctc tgatggagct ggtctatcag
    14581 gaggacaaaa gcaacgaatc gctctcgctc gtgctctttt aactaaagct cctgttttaa
    14641 tactagatga agctactagc ggtcttgatg tcttgactga gaaaaaggtt atagataatc
    14701 ttatatccct aactgataaa accattctct ttgtagccca tcgtctcagt atagccgaac
    14761 gaaccaaccg tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt agtcaccaag
    14821 agttaatgca ggcgcaaggc ttctaccatc atctattcaa taaataagga gaatgtcatg
    14881 aatcctaatc tttttagaag cgtcgagttt tatcagagac gttaccataa ctatgcgaca
    14941 gtgttaatta tacctctttc attactgttt actttcatct tgattttctc ccttgttgcc
    15001 acaaaagaaa ttactgttac ttcccaagga gaaatcgccc ctacaagtgt cattgcatct
    15061 attcagtcga ccagtgataa tcctatcctt gctaattatt tagtggcaaa tcaagtagtt
    15121 gagaaaggtg acttactcat caaatactct gaaacaatgg aagaaagtca gaaaactgcc
    15181 ttagcaactc aattacaaag acttgagaag caaaaagaag gacttggaat tttgaaacaa
    15241 agcttagaaa aagcgactga tcttttttct ggcgaggatg aatttggcta ccataatacc
    15301 tttatgaatt ttactaaaca atcccatgat attgaactgg gtatcacaaa gactaacact
    15361 gaagtttcaa atcaagccaa tcttgccaat agcagttcat cagctattga acaagaaatt
    15421 acaaaagttc aacaacaaat tggagaatat caagagctga gagatgctat cataaataac
    15481 agagcacgct taccaactag caatccacac cagtcaattt tgaatcgtta tcttgtagcc
    15541 tcacaaggac aaacacaagg aacggcagag gagccatttt tatctcaaat taatcaaagt
    15601 attgcaggtc tggaatcatc tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt
    15661 gtagcaactt atgataatag tttagcaacc aaaattgaag tactccgcac tcaattttta
    15721 caaacagctt ctcagcaaca actaaccgtg gagaatcaat taacagaatt aaaagtacaa
    15781 ctagatcaag caacgcagcg cttaggaaac aataccttaa ccgctccaag taaaggtatc
    15841 gttcatctga acagcgaatt tgaaggtaaa aatagaattc caactggtac agaaattgct
    15901 caaatattcc ctgtcatcac agatacaaga gaagtactaa tcacttacta cgtatcttct
    15961 gactatctac ctctactaga taaaggacaa actgtaagat taaaactgga gaagattgga
    16021 aatcacggca ccaccatcat cggccaactt cagacaattg atcaaactcc taccagaaca
    16081 gagcaaggta atctctttaa attaaccgct cttgcaaaac tatctaatga ggatagtaaa
    16141 ctcatccaat atggcttaca aggtcgcgtc actagtgtaa ctgcaaagaa aacatatttt
    16201 gattatttca aagataaaat tttaacccat tctgattaat tttcagataa cactctataa
    16261 ctatttatta tcttatcaaa aaggagaatc ataacatgga taagaaacaa aacctagctt
    16321 catttcaaga actaacaact accgaactca accaaattac aggtggagga ctgtgggaag
    16381 atatcttata cagccttaat ataattaagc ataacaatac gaaaggactt catcatccaa
    16441 tacaactata aaaaataaga ccgagtaaca agaactctcg gtcttatttt tttcatcatt
    16501 ctgtaggtat catagtaagc acctgacgaa agacttgatc ttgacaggta gtatttaaac
    16561 tggcattggg ataactttcc acaatcttca taacggtata gagaccgaca cctctctcct
    16621 cccctttaga actaactcca aaggagaaga tttcagaaat atcgatgccc tcttctttga
    16681 tggaattttc gatgatgaag gtctcctgtg ctccactttt taaaaaggca attgaaacat
    16741 gaggttgacc ggcctctgca ctcgcttcaa tagcattatc acaaaggata gacacaatgg
    16801 ttagaaaatc aagcagtctc atcccctcaa cctgaatctc ttcaggaact tcgacattaa
    16861 agacaatgtt cttatctcta gcttttataa attttccagc taggagactt ttgagggcac
    16921 gatcccgaac attcaccaat cggccaaggt catatttatt gtcctgcaat tttttactag
    16981 aatcctttaa gaccaagtca tagacctctt ttatctgctc catatcctcc tcttcaatac
    17041 ccagacgtaa acttgtcaag aggttggtgt agtcatggcg aaaactcctt acttccttgt
    17101 aaagttcctc tatatgccga ctatagcgtt ctatatctct atagcgcaag acctgctctt
    17161 ggtccagtct atcatggagt ttgtccttca aataggtatc caatttcttg ataaccccca
    17221 taaaaaatag gaggtagaac actaggatga gatggcgaac agtcgttgat tgaatacctt
    17281 gctcatattc aaagtaagac agactttgta tcaccaaata gtaagccccc attatccagt
    17341 taatcttagt cagggacttt tgaaaacctg tatctagaat ctcccttctc aaactagtaa
    17401 aatcatagtc caaccatttc aaaaaggcta gagaaatgaa gaaattgaaa attattatac
    17461 ataacccagt gaatgagtag ccatcatata cttgcccttg tcccaaaaat ggaagcacaa
    17521 aataggagac tcctctataa aagagattca ccaatatcat tggaaagaga ccataaaaga
    17581 aaaggagttt tttaggaagc cctcttaaca ataagaaaga caagcctatg ccgtacaagg
    17641 gttccataaa ataagatagg taaacatttc ctactatata gctaatcatt acaaaaacaa
    17701 agaccaacag tatcttcaaa agaaaggcct taaaaatcct ctcgaaagta agattaattc
    17761 catccacctt aaagaaaatg acaatttcta gcccattagt aataagtgta tgcaataata
    17821 tccaaacaat attcataaac tctcctagtt cagtgtaagt tattaatagc ctcagacact
    17881 tccctgacct tataacgcgc gatcagacaa cttccaccat tgggaaaaaa aaggagtttt
    17941 tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg atggcactgc
    18001 aagagacggg gttcctgctt gaaaacctcc tctaaactcg ctgtaaattc cagcctgtct
    18061 gtcttggtat agagaataac acgatgggct ctgggagacg tttcgagata gtaaacctct
    18121 ttaaaaggat attggaattg ggcaaatttt gatttaaagt aaaagcaatc ttccgccaga
    18181 cttttactat cttgactatt ggcatagagg aggtctgtct cgattcgaga ttcaaactcc
    18241 tctgccgaaa gggccttatc aatatagtcc agagcagaca cttggtagcg aaaggacagg
    18301 ggcataaact ccgagtgagt cgtcacaaag acaatcaggg cataaggatc ccgatcccga
    18361 atctttctag ccacttccag tcccttcatc tcttcatttc gaatctcaat atccaaaaag
    18421 aatagctgat gggccccctt ctcatgcact tcagccagca gttggtccgg cttgccaaat
    18481 acctcaaaag agctaggaat gatatgatgt gctttcaaaa gtttctcaat cgtcgtttca
    18541 attctagtct gttgggaaaa atcatcctct aaaacaaata ttctcatctt cttactctcc
    18601 ctctttcaac catttttgac gaatttctct atagcgacgt ctggcatact tgacagcgta
    18661 ttgaccttct tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt ttaatttatc
    18721 aagattaacc aaacaatttc gatgacatct catcaaggtt tccccacatt ggttctcaag
    18781 attacttaaa ttttgaagta tattaaaact agcttcttct gtaacaatct gtacggtatg
    18841 ggctttagtt ggatgtgttt ggatatagta gatatcgtcg atgtttactt tatagactgt
    18901 tttctgcgtc tgaataatca tatatttcat tggattctcc tcctaagaaa agaataacag
    18961 aaaaggtcta gcccaagcac acccaatcct aaacagtctt tgaaaactcc taaaaggatt
    19021 attttctaca acatcatgat gagcttacaa ctattttatc ataaaattca ctcagcgcaa
    19081 ttcaagacat ttcaatgaca attaaagatt tgaataaaaa aaaagaatta aaagtgataa
    19141 actaacagta tcaaaacaca gttgccagaa gtaagactgg cacccagatt aaaggaggca
    19201 ttcccatgac agatacagac cccatcaaaa gagctcatac tttgattact gacttaaaca
    19261 aagcctacca agcatgcaaa caggcaagcg ctgacgacgt ccgctttcag gagcaattaa
    19321 actctattct tggttttcta gccaaggctg aaacagtgga taatcgattc ttgattgaac
    19381 tagaaaaatt ttaccagact tccagtcttc tcatgggact cagcgctctt gatccagatg
    19441 ctccaactcg cgccgcttgg cgggcctatg accgcttcca ctttgaccaa gtcaagacca
    19501 agttaatact caatgaaaat caaagagcaa actaggaagc tagccgcaag ctgtacttga
    19561 gtacggtaag acgacgctga cgtggtttga agatattttc gaagagtata agtctctacg
    19621 gaccaaccat tatcctgtag taacaaaaaa gaagttgaga cagactgaac tcaacttctt
    19681 ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga taaggcaaat
    19741 acaagactag taaaaccaaa ccagctccta gtaaggctag aagggctagt ttttcttgga
    19801 aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat cctcgaacta
    19861 cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg gtcaaatact
    19921 ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag ttaaagagaa
    19981 ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagt acggaaagta
    20041 agagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa cgcagataga
    20101 gattttgcca aatcttccca ggcaccttct gaacagcctt taaaataaag tccagatagg
    20161 cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca aagaaacgaa
    20221 gcaagacttg cttacgcttg ctttcttgag aaataagata gtcccagtcc agtccagttt
    20281 cagtgaaaaa tttgctggcc ttttgacaaa agtggaaata ttttcctacc cccaataaaa
    20341 gcacatagag cagaaaaact ggcaagccat aacccattgc caaaaataaa ggcgcaaata
    20401 acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca gtttgacgct
    20461 tgagatggag cttgatttcc tcttctccaa ctaagagaaa gagcttgtct ggagcctcca
    20521 tataggtggc aattcctccc caaagtaaaa gtaaaacaga cgtaattcct acaaacaaaa
    20581 ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg taggctagaa
    20641 agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag cgcagataac
    20701 caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc ataggtcctc
    20761 ctcttttgtc agagccaagt aaatatcatt caaactagcc tcaggcatat caaaggcttc
    20821 gcgtagttgc aggagattgc ctttggcacg cacctctccc ttgtgaagaa tgacaaaggc
    20881 atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag acttgccctt
    20941 ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat caagaccaag
    21001 gaaaggctca tccacgatga aaaggcttgg atccaccaca aaagcacaga taatcatgac
    21061 cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct ggtccagacg
    21121 gaacatcttt aacaagggct ctactcgttc gaaagccact ttttgctcaa taccgtaagc
    21181 catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac taggcgtctc
    21241 aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag tcaggccatt
    21301 gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga tcgtcgttga
    21361 tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa cagtaaagga
    21421 cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa tttctaacat
    21481 attttctcca aatctggtat aatgtagcta tattatatca aaatttagta cagtagaggt
    21541 agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc ctgcttcaaa
    21601 agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa cactaggaca
    21661 caccttggtc gtgccaaaag aacactatcg caatcttttg gagatggatg ctacgagcgc
    21721 cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag tcactaaggc
    21781 tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag tttttcatac
    21841 tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg attttatcgc
    21901 ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa acgcttaagg
    21961 agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg gaagttatct
    22021 ggttacaaaa aatcgccaaa ccatcacaga tgaagtcttg aataccactg accgcgttca
    22081 agctatcaag gacgatgtgg atattatcca aaacagcctg caaatcatta accagcaaaa
    22141 agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct tggaaaagga
    22201 tatccagact agactagctg tgataaaaga aatgcaggga actgaagata agtaaaaaga
    22261 gccccccggc tcttttttaa aacgtaaaca agttatagtg aattgaattt agaatagcac
    22321 accatagttt ctaaagcatt gttagagatt actttaaaat cctcttatca atttgttcat
    22381 attctatttc aatctattat atatatccca tcaactatgc atcataattt aggtaactca
    22441 tactcaataa aaatcaaaaa gcaaactaga aagctaggca cagactgctc aaaacaccgt
    22501 ttt
//
LOCUS       DBEJZJ010000031        22446 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000031 DBEJZJ010000000
VERSION     DBEJZJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.31"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            28..484
                     /locus_tag="ACL3R8_001526"
                     /pseudo
     CDS             28..484
                     /locus_tag="ACL3R8_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            649..948
                     /locus_tag="ACL3R8_001527"
     CDS             649..948
                     /locus_tag="ACL3R8_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR1314382.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL3R8_001528"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL3R8_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR1314383.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(2262..3989)
                     /gene="ezrA"
                     /locus_tag="ACL3R8_001529"
     CDS             complement(2262..3989)
                     /gene="ezrA"
                     /locus_tag="ACL3R8_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR1314384.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4071..6017)
                     /gene="gyrB"
                     /locus_tag="ACL3R8_001530"
     CDS             complement(4071..6017)
                     /gene="gyrB"
                     /locus_tag="ACL3R8_001530"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR1314385.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6032..6595)
                     /locus_tag="ACL3R8_001531"
     CDS             complement(6032..6595)
                     /locus_tag="ACL3R8_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1314386.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6680..7234)
                     /locus_tag="ACL3R8_001532"
     CDS             complement(6680..7234)
                     /locus_tag="ACL3R8_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR1314387.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(7245..8468)
                     /locus_tag="ACL3R8_001533"
     CDS             complement(7245..8468)
                     /locus_tag="ACL3R8_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR1314388.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8505..10955)
                     /locus_tag="ACL3R8_001534"
     CDS             complement(8505..10955)
                     /locus_tag="ACL3R8_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR1314389.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11155..12084)
                     /locus_tag="ACL3R8_001535"
     CDS             complement(11155..12084)
                     /locus_tag="ACL3R8_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR1314390.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            12224..12511
                     /locus_tag="ACL3R8_001536"
     CDS             12224..12511
                     /locus_tag="ACL3R8_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR1314391.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12545..13879)
                     /gene="ciaH"
                     /locus_tag="ACL3R8_001537"
     CDS             complement(12545..13879)
                     /gene="ciaH"
                     /locus_tag="ACL3R8_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR1314392.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13869..14543)
                     /gene="ciaR"
                     /locus_tag="ACL3R8_001538"
     CDS             complement(13869..14543)
                     /gene="ciaR"
                     /locus_tag="ACL3R8_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR1314393.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14652..17198)
                     /locus_tag="ACL3R8_001539"
     CDS             complement(14652..17198)
                     /locus_tag="ACL3R8_001539"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR1314394.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQHLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17321..17761)
                     /locus_tag="ACL3R8_001540"
     CDS             complement(17321..17761)
                     /locus_tag="ACL3R8_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR1314395.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(17736..18605)
                     /locus_tag="ACL3R8_001541"
     CDS             complement(17736..18605)
                     /locus_tag="ACL3R8_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR1314396.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18583..19083)
                     /locus_tag="ACL3R8_001542"
     CDS             complement(18583..19083)
                     /locus_tag="ACL3R8_001542"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR1314397.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(19094..19792)
                     /locus_tag="ACL3R8_001543"
     CDS             complement(19094..19792)
                     /locus_tag="ACL3R8_001543"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR1314398.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19785..20021)
                     /locus_tag="ACL3R8_001544"
     CDS             complement(19785..20021)
                     /locus_tag="ACL3R8_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR1314399.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(20121..21047)
                     /locus_tag="ACL3R8_001545"
     CDS             complement(20121..21047)
                     /locus_tag="ACL3R8_001545"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR1314400.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21122..21937)
                     /locus_tag="ACL3R8_001546"
     CDS             complement(21122..21937)
                     /locus_tag="ACL3R8_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314401.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21941..22261)
                     /locus_tag="ACL3R8_001547"
     CDS             complement(21941..22261)
                     /locus_tag="ACL3R8_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR1314402.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6806 a         4873 c         3982 g         6785 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca agctgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctatcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaactggta aaaagtcagc tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aagacctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactagg cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatca gaggaaaggt
     1201 attgtactat gatgattcta ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga
     1261 cagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaataccgc tttaaagccc
     1381 tctactggga tggtcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacatc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 acttctaaaa cattgttaga aatcaatttg actgtcctga tcgatttgta ctgttcttat
     1621 ttcattttac tatagaacga tttgaaggcg tttatgatat ttagctgtac gagagtcttt
     1681 taaaagtgtt ttgatggttt ggatttcttc tttagttgat tttatattac tattatataa
     1741 tactttttta ttttagtcta gtataaataa cgagaaatat ctatcctatc ttctagaatg
     1801 tcttccaaac gagaaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggga
     1861 ctaaagttgt acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt
     1921 tctctagtct ggagattttt caatagactt cgttattgga cggttaccaa gttactcaaa
     1981 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     2041 aaaagcaaac taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg
     2101 tgatttgaag agattttcga agagtataaa acactgtttt gaggtggtgg ataaatcggc
     2161 tgggtaaaaa ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag
     2221 atttgattct gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca
     2281 cgtgttttct catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat
     2341 gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa
     2401 gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc
     2461 aagagttgct ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct
     2521 tccatatcat tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt
     2581 tgttctaact caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag
     2641 aaagtttgtg gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga
     2701 cgattgacat aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc
     2761 aggcgctcac taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc
     2821 tcaagatttt cttcaagaac tgaataagct tgggttggtt cttcttgatt cgaagttacc
     2881 tcaacaatag ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atggcttgca
     2941 gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta
     3001 ttattctctt tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact
     3061 ttctgagcag caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc
     3121 tgtccattct catattcggc attatccaat tccaactgac gaatattctc ttggtttttc
     3181 ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa
     3241 ttagcatcaa ttagtttacg ataaccggct tccaaatcct gtaattgatc tggcaattct
     3301 gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg
     3361 tgattttctg tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag
     3421 gttacaaatt gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag
     3481 gcttgaccat actgttctga attttcagca actctatgct gaagttcctc aaataaatcc
     3541 aaagcatgaa gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca
     3601 ttgcgaattg ccgcaatatc ttcttcaatc aaagtaattt gactctcaat ttggtcaatt
     3661 tgatgactgg ccttgagaaa acgaaatgaa tggttatagc cttctgcttc aaagagatta
     3721 ttttcaatat cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg
     3781 aaagccactt gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt
     3841 actggaagat tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt
     3901 cgcttacgta gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc
     3961 attaaataaa ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt
     4021 aacgattata tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca
     4081 agtgtactat agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc
     4141 atcaacatat caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc
     4201 aagcgatgtt cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc
     4261 cccttataac gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct
     4321 tggagtttga tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc
     4381 ttgacaccat agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc
     4441 atataacgat aaatcaaggt taaaagaagg gtacgaatgt gggctccatc gacatcggca
     4501 tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat
     4561 cctgttccca tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata
     4621 cttgcttttt caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg
     4681 ttacgaccag atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt
     4741 tcagcagggt tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa
     4801 ccagattttt tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct
     4861 aaaatccctt tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag
     4921 aaggcttcac tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc
     4981 ttggtttgtc cttcaaactg tggatttggg tgtttaactg agataactgc agttaagcct
     5041 tcgcgaacat cttcccctgt taggttgtct tcattgtctt tcagtaactt atttttacga
     5101 gcataatcat tgataacacg tgtcaaggct gtacggaaac cttgttcatg cgttccacct
     5161 tcatgtgtat gaatattatt ggcgaaactc atgacatttt catggtaacc agttgtgtac
     5221 tgcatggcta cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca
     5281 aagattacat ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa
     5341 tgataatgct tggtttgttc caaaccttca cgcttatctg taattgaaat ttgaagaccg
     5401 cgatttagaa aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaagattgtt
     5461 gtttcagtga agatttttgg gtccggtgtg aagtgaacag ttgttcctgt tttatccgta
     5521 tctccaacta tttcaagatc tgcgacaaca tgaccacgac ggtattcttg gtaatgaatc
     5581 ttaccatttt tgtgaacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac
     5641 cccaccccgt gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagcg
     5701 tgaaggactg taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact
     5761 gggataccac gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga
     5821 atatggctgg caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact
     5881 agatggtgaa gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca
     5941 gcctctaagc cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt
     6001 ttgatttctt ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca
     6061 cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg
     6121 gccgatcacc aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg
     6181 attcgggatt tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag
     6241 ctgctataga ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa
     6301 aatgacggcc accttgattt gaaatgactt ccaataggtc agaaactcct tcaaataaaa
     6361 tcgggtgttc aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat
     6421 tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt
     6481 catggtcttg tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt
     6541 cataattatc cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct
     6601 tcattatagc atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa
     6661 cgagagaata actcccgttt tactgatttt taccaaagac atcttgatag agcattcctg
     6721 ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg
     6781 ctgttgaagg accccgactg gttgtcaact gaccatctac cactactgtt tccttgacat
     6841 agtgaccatc aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca
     6901 atatctctgc ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt
     6961 cttgctcgaa gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac
     7021 caggcatacc tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat
     7081 gatctgctct tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat
     7141 cacatgtgat attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa
     7201 agccctgagc taacataact gctactttta ccatgatttt ctccttattt aatttgtttt
     7261 aatacaacct ttttccgttt gaatgggact tttccgctct tttcttcagc tagattagtc
     7321 tggtaactca tcgataaaag caaaccaaca ccaatcagat tactgataat agctgatccc
     7381 ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg
     7441 atattctcaa agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag
     7501 aactggttat ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg
     7561 gcaataacca ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata
     7621 tctgactctc gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca
     7681 ccactcccaa tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca
     7741 aagggattga gccaagccaa aatccgatta atttggtagg tcggcattcc aatctggtga
     7801 agaaaagctc gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca
     7861 gcagtcacaa atactgggat aataattttc caagaaaccc ctgataataa aacgattcct
     7921 gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact
     7981 aggactggaa tggtaaagag aatcatccag aaaattaaca aaaagtccag cggaaccgtg
     8041 cgtctccatt ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata
     8101 taggatatct tcataaattc tgacggttgg aatagggtaa ttccatttat tgatacccag
     8161 tttttggcac ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata
     8221 agtcccaagc ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag
     8281 agcatgacca caaaaccaat cacaagcccc aaagcaatcc aggcgacctg ctgccctaaa
     8341 atgggcagaa tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg
     8401 atgaccagta gaaaaaatac tggcaagagc aaactgtaat cgactcttga gtcgagagaa
     8461 cgtttcatat atactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa
     8521 aatctatcaa tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct
     8581 gctagagatg ctactatttg tttgccgtat cgttttccga cgattctcct atccaaaata
     8641 agagttaagg aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga
     8701 ataatggcca ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct
     8761 tgattaatct ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact
     8821 tgaatcacaa aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc
     8881 aagatttgtt gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta
     8941 tactgggcca agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg
     9001 gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc
     9061 tctctggcat agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccatgacc
     9121 acttcttgtt cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct
     9181 aaaaggtctg ccaaagaaac cctctgacta atctcaagag tagctgatac tcccaagact
     9241 tggcaactct caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaatc
     9301 tgaattttct tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa
     9361 tagcgaacca gctcatcaaa gccttccact tctaattctg aaaaatactg atggagattg
     9421 tccagagaat ctaagatatt tttcctagat ttgccagact gaaattgttc tatcaagtag
     9481 agacactcaa agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact
     9541 aaagccttat caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt
     9601 tctagagcta acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat
     9661 tcaggattat cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa
     9721 gtctctgccc tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat
     9781 gataaattcc catcatgacg aaggtctgct agaaaatgtt ggtaacggta gagttgcccg
     9841 atttcatcca aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag
     9901 cgtctaaata agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc
     9961 agataatttt gtggtccctt taagctatga atatctgtat ggaacacttc cttgagacgt
    10021 ttaccttctt cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt
    10081 tgtcgctctt tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct
    10141 gtcggcgctt gaatcagaga gacaggttca tctttcaata gcaagccaac ctctttagca
    10201 aaactttctt gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct
    10261 tgagatagtt ttcgtagctc cagagaagct gccgttttct taaaatacag accttgaact
    10321 tggaccaagt ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg
    10381 taggactcat ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga
    10441 agctgggtca tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa
    10501 agggctgtgt gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta
    10561 tatttttcca gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt
    10621 cttagctcat agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca
    10681 ttatgggcta caaaaatccc atcctccacc aagtcaaata tttttctggc aacttgcgaa
    10741 aaatcaggtg cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca
    10801 tccaagggtt catgtggatt gacatccgtc gtatagtgat cgacgatttc tccgtcctca
    10861 atcacgacaa ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa
    10921 tccaccacaa catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg
    10981 gccatttggc acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttaa
    11041 aaatcccatc gaatagagca ttctagcctg ctgatttttg taaaatagtg aagaaatacg
    11101 aaaaattgag agaagaaatg tttgcatctt ccttctctca acgaatcatg tattttatct
    11161 aaccatgtca ggatcgtagt cataaaatcc tgtatcaagg aaacggtttt tagggtgaag
    11221 tttacgaact tcttcatcca gcaagaaggc ttgatcatgg ctaaagttgc cctcttgaat
    11281 caaattacgc gcttggataa agagttttgc aatctcaaca aagttctgac caggagtgta
    11341 gagcccttct agtttccagc gagtaaagcc atgctccacc aattctgtta atttgatcat
    11401 caaatcaagg tcattgttgg caaagatatg ggtcccatga ttatcttcaa aaatggaata
    11461 gtggctctct ggatcacttg gctcagccaa gaagaggtca cgtttatgcg tcttttcatc
    11521 atcgatatgt gtaaagttat agtagttttg caagagtgga cgtttagaat gatggatgac
    11581 gctagcaccg taaaccaaaa cttcagcagg aatttccaaa atctctggca ttttgaaaag
    11641 ttcagctgat ggaatttcac gcgccaaaac agcctcagat gcgccagcct tttgccccca
    11701 gaagttaatc tgacgactgc tagttaccat ggttgaagca tcgtagatgg tcttaaatga
    11761 ataaccatcg cggttaacta cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt
    11821 cttgatttct tccaagaagt ctaagaaagg cttgatacgg tccatcatat cttggtgcat
    11881 gagagcattg accgcaacga gcaattcctt accagcatca tgaaccaact tagcgatttc
    11941 acgtaattgg tcataactaa aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac
    12001 atagatacgg tctacgccag cttcgagtag ttgttcaact tgttcaatac tttcagcagt
    12061 tgctgtaatg acaatctttt ccataagaaa aattatacca catttctcca aaatcagcca
    12121 tgctttgaaa atgaaaaggg actttattct ttttgtaacc tttctgtaat aattctctgc
    12181 cgaaaaaatg ataaaatagg tatgtactgt taaggagaga atcatgcccg taagaaaatt
    12241 acaatcctat gaggtagact atcaagaaga attaaaccag cagcttcctc attaccaagc
    12301 ttatacacct gaagcgcaat ctgatgccaa tctcaaggaa atcctatttt ttattaatat
    12361 cgctgttttt tgtatctgta ttgctatctt tagttttatc tttttagcat taaaattatc
    12421 aactgctctt gcctttgccg cagcaatcgg attcagctta cttgttttaa aagttcaacg
    12481 gtctattatc aaacgaaaac gtagaagata aatccaaaat atcgccccaa ttggagcgat
    12541 atttttattt tttcttttta gatggtgtct gaatggcaat cttcacttca aagattgttc
    12601 ccttgggttt attatctttg acagtaacag ttccttttag agcatctaca atttgcttgg
    12661 ctagggataa tcctaaacca aaaccacctt tttgccgggt tctagctttg tctactcgat
    12721 aaaaacggtc aaaaattttc tttttatctt ctgtcgaaat accgattcca ttatcagaaa
    12781 caagtaaata aagattgcga tcggtcgccg agataagaaa atcaatttca ccatcctcct
    12841 cagtatactt gacggcatta tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat
    12901 ctgtgacaat tgttcgatgg atacgatttt caaaacggaa gacacgatta ttttccgaag
    12961 caatcatctc gtagtttgtg aaagttgtat taaaaaagct agttggaact tctgcaagct
    13021 ccggcttaat cccatcatct ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca
    13081 tatttcggac ttcttccaaa ctcgatgcaa tgctttcgct cacatccata atggtagctt
    13141 ctggcttacg aaaaagggtc tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact
    13201 catgactggc attttccaca aaagactgtt gcttctgcat actctcaagc aggggcctaa
    13261 cactgaccct agctagatag agactggcaa gtaaagacaa aatccagaaa ctagccatca
    13321 cgaccacaat caattgctca tgcttttgac tagcctgctc caactgactg gtattaatca
    13381 agacagcagc atactttata ttggttgaaa ccgaactaat attggtctcc atcaaaatca
    13441 cacgatagat ttcttcctgc ccatagctat taaaaacctg aatctggtag atatgtccta
    13501 gttctttctt ttctaactta atcttatcca agcccaaaaa tcgatttcca gaaagaagtt
    13561 gagtaaagtc tttatcaaag agaatgactt ccgtattgga actgacatta ggttttattt
    13621 ctactttact agcgtccgcc ctagcatttt ctaaatcttt aatctcttct gttgccctat
    13681 ttatagccag ctgaataact gcttgaggat tttcactcag tccatgaagc ttatcgtcca
    13741 ccgaagtata aagactcgaa tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa
    13801 tcagggtgaa gacaccgaag ttgcggataa aataactaaa gtcatccgca taccatgttt
    13861 ttttaagttt actgaacatc ttttaaaaga tacccaacac tacgcaaggt ttgcaaattc
    13921 tctgcaaaag tggttccctt taatttctta cggacttttg aaacatagac ttcgacaacc
    13981 gaaatcgttg tatcactatc aaatccccat agacggtcaa aaatctgcgt cttaggcaaa
    14041 atcacatttt gattttgaag gaaataaact agtaaatcga actctttccc cagcaattcg
    14101 acaggagtat cttcaacttt aacggtattg gttgataaat taaccacgat attcccataa
    14161 gtcaaggtgt tttcattaaa cttccctgaa cgtttgagaa gggcctgaat ccgcatttta
    14221 agttcttcta ggtagaaagg tttggtcaga taatcatccg ctcccagttc aaatccatgt
    14281 cccttgtcat ccaaactttc cttggcagtc ataatcagaa ctggtgtcgt aattcccttt
    14341 tcacgcaatt cttttaagac ttggaaacca tttttttctg gcaacatcaa atccagcaaa
    14401 atcaagtcat agacaccact ctcagcttcg tagagacctt cttctccatc aaatacctgc
    14461 ataacatccg caaaatcgtc taaaaagtca aatactgaat ttgacagacc taggtcatcc
    14521 tcaaccaata agatttttat catgagaaac tcctccttat taaaactatt ataccaaatt
    14581 tgccttaaaa aaaactcaac tctctgcatt ttacatgaga tagctgagtt ttctttttat
    14641 tttaggctta tttatgcatt tccgtattga agaacaactg cttcgactgc agctttttca
    14701 cggctaatca agtcaacacg cgctgcaatt tccttgattc ccataccgat gttacggcta
    14761 agagcaaggt cagaaagttg cggctcaaag aactccttgt attccgccaa gtgttgctga
    14821 gtcttaaata catgagcagg aaggataaca aagctatcaa agctcatatc tcctccaagg
    14881 gctgccttaa tccaagccca gttttcacgc gcccaagacc aagctgtttt ctgagttgct
    14941 tgatgagcta ggaattggta ataccaagca gacaagtcct gtggtttgac cacaaatttg
    15001 tccttccaag aagtaatcaa gttttggata ttatccgcat ctgtactgta tgcaagagct
    15061 gctgccaact ggcgtttaaa gacagcatct gttgcgtgag tataagtatc aagataaagt
    15121 gctaacaagt ctttagtctc atgatgtttc atctcattaa tcagaacttg tgaacgaata
    15181 gctgctggga gtcctgcaag attctccttg tgtgttgcga agatttggct agcgacttga
    15241 ctagcttctg catcatttga gcgaatcatc atcgaaacag ccagctgacg aaccaattca
    15301 tcctcatctg attctccgtc tttagcttca aaaccaagac ggtcatagtt atgacgagcc
    15361 aatttagcaa ccagtccttt gaaggctgtt tcagcatccg ttccttcatc aataaagcgc
    15421 tcaagggctg aaatcacttg agaaacagct gaaaccacca gataagactc ttccttagca
    15481 agtttatcaa gaactggaag caagtctgca taagaaatgt gccctgcctc agccaacaaa
    15541 cgacgttctt gaacaatttg cagtttgctt gtgttatcaa gtgtctctag ctcagcaaga
    15601 acagcttcta acaagtctcc ttgatagtcg gtaatatagt gggcagtatt ttcagtgttg
    15661 agacgaagag ctccttcatt ttcagcaaga agagctgcgt agccagggat ttcgatactt
    15721 tcagtttcga gtgtatcagg caagcctttc cagttgctat tgaggggcac cacccagaga
    15781 cggttcttgt cttcgttctc accgatgaag aattgttttt gtgaaatctt caagacatca
    15841 ttttcaactt taacagtaag aactgggtaa ccaggctgtt ccaaccaaga atccatgaag
    15901 gctgcgacat cacgtcctga cgcttgacca agggcatccc aaaggtcact accaatggtg
    15961 ttgctgtatt ggtgtttttc aaagtaggcg tgcaaacctt tagcaaaatc agcatctcct
    16021 agccaacggc gaagcatgtg catgagacgg cttcctttgg catagacgat agcgccgtca
    16081 aagagtgtat tgatttcatc tggatgttta acttcgacgt ggacagactg aacgccatca
    16141 gtagcgtcac gttcaagagc aagaggtact ccacctgttt ggaaatcttc aaagatattc
    16201 cagcttggtt cgatggtatc cacacagacg tattccatca tattagcgaa actttcattg
    16261 agccaaaggt catcccacca tttcatagtc acgaggttcc caaaccattg gtgagccaat
    16321 tcatgggcca caacaagggc aacttgttga cggctagcaa atgtagagtt ctcatcgaca
    16381 accaagtaaa cttcacggta ggtcacaaga ccccagtttt ccatagcacc agctgagaag
    16441 tcaggaaggg cgatgtggag agattgagga attgggtact taactccata gtaatcttcg
    16501 taaaactcga tagagcgaac agcgatatcc agtgagaaat caagatttga aagtggatgt
    16561 gctttggttg agtagacacc taccagggta ccatttttag ttttagcggt caccccttgc
    16621 aaatcaccag caacaaaggc caacaagtaa gaagacatgc gaggtgttgt ctcaaacttc
    16681 cagatacctg tttccttacg gttttcaaca tcgatttctg gcatgtttga caaggccaat
    16741 tcaccttctg cttggtcaaa gcgaagagag aggtcaaaag ttgctttggc ttcaggctca
    16801 tccacacatg ggaaagcttc gcgcgcaaaa tggctctcga actgagtaga caagacctcc
    16861 ttcttgactc catcaactgt ataataagaa gggtaaatcc ctgtcatgtt gtctgtaatt
    16921 ttaccagaaa aggcaagaac caattcaact tgaccagcct cagccaattc gatatgaagg
    16981 gcttcattgt catggtcaac tgtaaatgga cgagcttgac ctgcaacttc tacagaggtg
    17041 atttccaaat ctttttggtg gagggagatg cggtcactct gtgcttgacc agtgatggtc
    17101 actttcccag aaaaagtctt ggtctcacga ctcaaatcta aaaataaatc ataatgttca
    17161 ggaacaaatt gcttaataaa atgttcaact gcttgcatag ttttctccta ttctaagttt
    17221 aagagctgct gctcttcttc aaacaaactt attatatcat attttgcttg agaaaaaagg
    17281 attggacagc gatttccaaa actttcttcc ttctaatagt ctacagtggg tagaccttgc
    17341 gaaattcttc taaaacaacc ttgctttcag gtgtaaaagt caatcctgct tcacccaagc
    17401 agtctctgaa aaaatcctca tgaacctggc gccaatagac aagtgtcttg tttccctcac
    17461 cttccttata ggcatggtca gctgacactc gattgaaggg tttaacagaa acctttgtaa
    17521 tttcgacaat gcagacagcc tgattttgac tatctaaaat gacatcgaag gtccctactt
    17581 ggggaagtgg ttcgtcttct agtacataga ggtcataggc tgatgctgtt gctgtctttt
    17641 ctcctttaaa caccaaatcc gctaaaaggt ctggttcaac tccaaaagcc caggcatcga
    17701 tttcatctcc gatagaagga ttgatttgtt tgtatttatt ccacatttct tgcggtatca
    17761 tgggtactcc tttgtaattt tttactttct tcttttatgt gtttaagatg atctggatgg
    17821 tcaatctcta aatcaaaaat ctctggaata gaactgtagt ggataatgca cttgataccc
    17881 aactgattca ttttttgtat gaaagaagta ttcagatagc ctgctacagc aaaattaatc
    17941 ttgttctttc ttgctttatc ctgcatatct cttagcatat ctaacattat tggactttcc
    18001 atatcatgcc attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt
    18061 ccaactacaa tctttgaaat gcccgtttcc agtatactag ataagtcaaa atacgctgac
    18121 ggtaattcaa tcatcgttcc gactttccca gtaaaaccct gctgacgcaa tactgtaata
    18181 gcttgtttta attggtcgtc atcattgaca aaaggaaaga taacagatag attggggttg
    18241 gtttgataaa cttctgtaac gacatgtgct tcagcctgaa attcatccaa acacgccagt
    18301 aaacgcctgg ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa ctctctagtc
    18361 cccactaaac aattggcttc tgtattcgtt aattcagaaa aacgatacca aacttcttca
    18421 tctgagtaca gggagcagat agtctctaga taatctttta caaattgctg acaacttgct
    18481 aatatgatgt tttgattaag ctctctcaac aaatattccc cacgaatcat gccgacgtgg
    18541 tgaaatagtt gaggataaat tttttcaaga attttttcgc cactaagggc aagttgattt
    18601 ctcatcattc accttccaat tcatgtaaga agtcttgtcc agttctggaa atcctaataa
    18661 ttcagactta accttcaaga ctaatggcga tgcattttct tctgtaattt cttgaatatc
    18721 catccaaata tatccaagtg aatcattcgc accatcagac acagcttccg aagtcgtaac
    18781 ttgaggtgca ctctcattca tttcaacatc atacaaggcc atgacatggt gaaccataaa
    18841 attttttaac tcttctctga cgaaaacatc gtagattcga ggattagagt agcttctaac
    18901 agtaaatctc gtctcttcca taacttctct agtcagcgtt tccgtcagtc cttcaccaag
    18961 ttgctgactg cctccaggta gatcataccg atgttgataa gggcctctcg ttttttcaat
    19021 gcaaagtaac tttccatttt caaagcaaac acagtagacc ccaaagtgtt ttttgatttc
    19081 catccaactc ctcctacttc aaagaccagc caccatctat tgtcaagatt tgtccttgca
    19141 tggcgctcgc ttttccactt gctaaaaaaa gactaagctc tgctatttcc tctggctcaa
    19201 tccagcgctt gattggggtt tcactagcca cccagtcagc caaaccacct ggttcaaaat
    19261 ccgcagcggt catagctgtc ttgactgctc ctggagcgat accaaagacc tgaatcccag
    19321 cttcagcata gtctagagcc aactgcttgg tgaagccagc caaggcatgc ttggatgaag
    19381 tataggcgtg accacctcca cctgctaggc tagaagcaat ggaacacata ttgatgatga
    19441 ttcccttttt attttccagc atttgtgtca aataataccg agtcaactct actggaataa
    19501 tgtagttgat ttcaaaaatc tcttgaatgt cctgcgccgt ttgttccaac agtggtttgt
    19561 aatcatccaa aactccggca gtattacaca aaacatccac ctgagggcac cagtcaaaaa
    19621 taggttccaa gtccaaggtc aaatctctct gtaaaaagtg aaaatcaccc tctaagagtg
    19681 gcttttcacc ttggtcaact ccataaactt gatagccctt ctctaaaaag aggcgagctt
    19741 gagccaatcc gatccctgaa ctcactcctg taatgagtac acgtttagtc atgcacttct
    19801 acccaatccg ttgccaaaac atcacaagct gtcgggctcc acatggaaaa accttctcct
    19861 tctccagaca cgttgattag gaaataaggt gtcacttcaa gtgcaagccc attttgctcg
    19921 atggtatcaa agagttggac atagttttcc gcacctcccc aaccagttcg tacatatttt
    19981 ttcttagcct ttaagccagg taaaatttct tcaaatgtca tgtttttctc ctttaatgtc
    20041 aataattctc cccttcatta taacaaaaaa accgctttaa aacggctttt tgactgtgat
    20101 ttattcaaac ctgctactac ttacggcaaa ttattccctg cagcaagata aatttcatac
    20161 cattcttttc ttgttaagct aaagtttgcc gctcggctaa cttctctcaa gtgcttagga
    20221 tttgttgtac ctacgactgc ctgcattttt gctggataac gcaatatcca agaaatggca
    20281 atagttgaag aggttactcc atatttaata gctaaacgat caagtacttg atttaaagct
    20341 tgaaatttct catttccaac aaagttccct ttaaaatacc cgaattgcaa gacagaccat
    20401 gcttgaatga ccacatcgtg taatttgcaa tattcaaaaa tgctgccatc tcgcatagct
    20461 gcttgactat cttccatatt aacatgaaaa gctgattcaa atcctggagt aaaagccgca
    20521 ctcaattgta gctgattaac agctaacggc tgcttgacat cttttttaag caactccatc
    20581 atcataggat tttgattaga aactccaaaa tctcgaactt taccttgttt ataaaggaga
    20641 tcaaaggctt ctgctacttg gtcagattcc atcaaagcat ctggtcgatg aaggagcaag
    20701 ctatctagat gatcaatctt caatctttgc aaaataccgt ctactgattt tataatatag
    20761 tccttagaaa aatcaaaata ggtaaattct tcaatgcgaa tgccacattt ggactgaatc
    20821 cacatctttt ctcttaaatc tggacgattt tttaggacaa gacctaacag ttcttcacaa
    20881 cgaccacgac cataaatatc agccaagtcg aaggcattga ttccaacaga aagtgctgtt
    20941 tctacaagct cttcaacttc ttttacagac ttatctttta ttctcatcat tccgagaaca
    21001 atttctgata attctttgtc atcttgacca agagttatgt atctcatcaa atttttctcc
    21061 tttaatttct aacattcttc ccttcattat aacaaaaaac cgctttgcaa cggctttttg
    21121 actatacttc actccatttt atcttcttaa acccacggaa caagacaaag attccaataa
    21181 agaggacagc taaaggaata acttttgtaa ggaaaacatt tgaaattccc atccactcat
    21241 aataacggag cagagaaccc accacaagat gggcaataat catactgaca aatggacgaa
    21301 agaccgcttc tttccaattc caaataccga taactagcga aatcgtaaag acagacaaac
    21361 tatcccaggg agccggaata taaaaggctc cttcttgtat gaagcttgcc attcctacat
    21421 atcctaaaac aactagaaga actatagtcc caacaacaat gtaagtgcca attttcattt
    21481 taggagaatc ttggactaaa cttcttcgta aaattgtggc cacaagtcca aatccaatca
    21541 gaaaaataag aagttgccct aaaaatgtga gcaaattgac tgttaagaga ggacctttag
    21601 aaaaatcact tagtagttga taataacgta ataccgccag gacaagaatt ggcgtcaaaa
    21661 gggactcttt gatagaactg cgaggtgctc ccttgagaat ctctttcatt atttttttag
    21721 gattcttacc tagataatcc tctgcactca tgccatctcg ttctgcttct gagaaatcta
    21781 gcatcatcaa atagatctgc tctctgagat agtcttcatc atagagaaat ccagcaagat
    21841 taaaactttc ccacaactcc tcaaaatact tttgattctc ctcagaaaac tcatgtagca
    21901 aagcgcttgt ttcttcgtaa tacttcattt tcttcatggt ttaaccccca ttcttaatcc
    21961 cttctacttt ttgactcaaa tcgtcccatt gttgccaaaa gactgagaca cgctcttctc
    22021 cttctttcat taatgaaaaa tacttccgat ctggaccatc tggcgacggg cgcatgtcgc
    22081 ctcttatcca ttgatttttt tctaactttt gcaacaaagg ataaatagtt cctggaacga
    22141 tagtatcaaa tccagcctct cgcaaagtct gaaccaactc ataaccatac cgctcttttt
    22201 gaccaatcat atccaagaca caaccttcaa gaacaccttt taatagctga gtttctttca
    22261 tcacttctcc cttctaatct attttgtaat acctactagt aacttcacct atagtatatc
    22321 acttctacac tagtttgtaa agcataatag ttaatactct tcgaaaatct cttcaaacca
    22381 cgtcagcgtc gccctaccgt atgtagggtt actgacttcg tcagtttcat ctacaacctc
    22441 aaaact
//
LOCUS       DBEJZJ010000032        21988 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000032 DBEJZJ010000000
VERSION     DBEJZJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.32"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..189)
                     /locus_tag="ACL3R8_001548"
                     /pseudo
     CDS             complement(1..189)
                     /locus_tag="ACL3R8_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(573..1769)
                     /gene="tuf"
                     /locus_tag="ACL3R8_001549"
     CDS             complement(573..1769)
                     /gene="tuf"
                     /locus_tag="ACL3R8_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR1314403.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2680..3549)
                     /gene="gla"
                     /locus_tag="ACL3R8_001550"
     CDS             complement(2680..3549)
                     /gene="gla"
                     /locus_tag="ACL3R8_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR1314404.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3772..4293)
                     /locus_tag="ACL3R8_001551"
     CDS             complement(3772..4293)
                     /locus_tag="ACL3R8_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR1314405.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4251..5357)
                     /locus_tag="ACL3R8_001552"
     CDS             complement(4251..5357)
                     /locus_tag="ACL3R8_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR1314406.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5468..5722)
                     /locus_tag="ACL3R8_001553"
     CDS             complement(5468..5722)
                     /locus_tag="ACL3R8_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314407.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5716..5958)
                     /locus_tag="ACL3R8_001554"
     CDS             complement(5716..5958)
                     /locus_tag="ACL3R8_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314408.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(6080..6613)
                     /locus_tag="ACL3R8_001555"
     CDS             complement(6080..6613)
                     /locus_tag="ACL3R8_001555"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR1314409.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6600..6926)
                     /locus_tag="ACL3R8_001556"
     CDS             complement(6600..6926)
                     /locus_tag="ACL3R8_001556"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR1314410.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7160..8878
                     /locus_tag="ACL3R8_001557"
     CDS             7160..8878
                     /locus_tag="ACL3R8_001557"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR1314411.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAILVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8989..9336
                     /locus_tag="ACL3R8_001558"
     CDS             8989..9336
                     /locus_tag="ACL3R8_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR1314412.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9614..10450)
                     /locus_tag="ACL3R8_001559"
     CDS             complement(9614..10450)
                     /locus_tag="ACL3R8_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1314413.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10463..11092)
                     /locus_tag="ACL3R8_001560"
     CDS             complement(10463..11092)
                     /locus_tag="ACL3R8_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1314414.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11102..11743)
                     /locus_tag="ACL3R8_001561"
     CDS             complement(11102..11743)
                     /locus_tag="ACL3R8_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1314415.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11889..13118)
                     /locus_tag="ACL3R8_001562"
     CDS             complement(11889..13118)
                     /locus_tag="ACL3R8_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR1314416.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13108..14274)
                     /locus_tag="ACL3R8_001563"
     CDS             complement(13108..14274)
                     /locus_tag="ACL3R8_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR1314417.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14418..15431
                     /locus_tag="ACL3R8_001564"
     CDS             14418..15431
                     /locus_tag="ACL3R8_001564"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR1314418.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15476..15895)
                     /locus_tag="ACL3R8_001565"
     CDS             complement(15476..15895)
                     /locus_tag="ACL3R8_001565"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR1314419.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15906..17312)
                     /gene="atpD"
                     /locus_tag="ACL3R8_001566"
     CDS             complement(15906..17312)
                     /gene="atpD"
                     /locus_tag="ACL3R8_001566"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR1314420.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17398..18276)
                     /locus_tag="ACL3R8_001567"
     CDS             complement(17398..18276)
                     /locus_tag="ACL3R8_001567"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR1314421.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18292..19797)
                     /gene="atpA"
                     /locus_tag="ACL3R8_001568"
     CDS             complement(18292..19797)
                     /gene="atpA"
                     /locus_tag="ACL3R8_001568"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR1314422.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19812..20348)
                     /locus_tag="ACL3R8_001569"
     CDS             complement(19812..20348)
                     /locus_tag="ACL3R8_001569"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR1314423.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20348..20842)
                     /gene="atpF"
                     /locus_tag="ACL3R8_001570"
     CDS             complement(20348..20842)
                     /gene="atpF"
                     /locus_tag="ACL3R8_001570"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR1314424.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20856..21572)
                     /gene="atpB"
                     /locus_tag="ACL3R8_001571"
     CDS             complement(20856..21572)
                     /gene="atpB"
                     /locus_tag="ACL3R8_001571"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR1314425.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21607..21807)
                     /locus_tag="ACL3R8_001572"
     CDS             complement(21607..21807)
                     /locus_tag="ACL3R8_001572"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR1314426.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21882..>21988)
                     /locus_tag="ACL3R8_001573"
     CDS             complement(21882..>21988)
                     /locus_tag="ACL3R8_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR1314427.1"
                     /translation="KKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         6562 a         4730 c         3990 g         6706 t
ORIGIN      
        1 actcctcata tttttttaca tttcgccaaa tcattgtttg attacagtct aaaagttcta
       61 taatctcttt ataagatttg cccatatcag acgaaataga acgatttgaa gacgtttatg
      121 atatttagct gtacgagagt cttttaaaag tgttttgatg gtttggattt cttctttaat
      181 tgatttcata ttactattgt ataatgcttt ttgattttag tctagtatta tactcttcga
      241 aaatctcttc aaaccgcgtc agcttcgcct tgtcgtatag atgttactga cttcgtcagt
      301 tctatctaca acctaaaaac agtgttttga gcagtctgta gctaactttc tatagtaaaa
      361 tgaaataaga acaagacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
      421 aagtaaatgt gtactattct agtttcaata tattatagtt tgctctttga ttttcattga
      481 gtattagttc aatatctaaa aaaagaacct tgccaagcaa gattctttta gtgtctgact
      541 taaataattg ttcttctggg aactaaatcg aattaagctt cgatttctgt aaccatacct
      601 gaaccaacag tacgtccacc ctcacggata gagaatgtag taccttgttc tacggcgatt
      661 gggtgaatca actcaacgtc gattgtcacg ttatcaccag gcattaccat ttcagtacct
      721 gctggaagtt cgattgaacc tgtaacgtca gtagtacgga agtagaattg tggacggtag
      781 ttgttgaaga atggagtgtg acgtccacct tcttctttag taaggatgta gacttcacct
      841 ttgaatttag tgtgtgggtt gattgaacct ggtttagcga taacttgtcc acgttcgatt
      901 tcatcacgtt gaacaccacg aagaaggaca cctacgttat ctccagcaag accttcgtca
      961 agttgtttac ggaacatttc aacaccagta acaactgctt tttgagtttc ttctttgata
     1021 ccaacgattt cgatttcgtc gttgacttta acgataccac ggtcgatacg tcctgaagca
     1081 actgtaccac gtccagtgat tgagaatacg tcctcgactg gaagaagcaa tggtttgtca
     1141 gtgtcacgtt ctggttctgg gatatactca tcaactgtgt tcatcaattc cataacgatg
     1201 tcttcgtatt tagagtcacc ttcaagagct ttaagtgctg aaccttggat aactggaaga
     1261 tcgtcacctg ggaagtcgta ttctgacaat aggtcacgga tttccatttc aaccaattca
     1321 agcaattctt cgtcgtcaac caagtcaact ttgttcatga agacgataag gtgtttaaca
     1381 ccaacctgac gtgaaagaag gatgtgctca cgagtttgtg gcattggtcc gtcagttgaa
     1441 gctactacaa ggatagctcc gtccatttga gcagcaccag tgatcatgtt tttaacgtag
     1501 tccgcgtgtc ctggagcgtc gatgtgagcg tagtgacgtt tttcagtttc gtactcaacg
     1561 tgcgcagtgt tgatagtgat accgcgttcg cgttcttctg gagcagcatc gatagacgca
     1621 tagtctttag gttggttaac tgatgaaggc aagcgacgtg ccaaaacagt tgtgatagct
     1681 gcagttaggg tagttttacc gtggtcaacg tgtccgatag taccaatgtt aacgtgtggt
     1741 ttactacgat cgtatttttc ttttgccatt tgagtaaaag cctccaataa aatatatttt
     1801 atagatagac agtaggcaat acagtctaac tttccttact attttatcaa atttcagcta
     1861 aattgcaagt gttttacaac gtttttgtga attattcttg ataaaaattt aactaactaa
     1921 tagaaagtac taaatagact tatccttcaa ggagttttca gcattatcca tccactcact
     1981 tgctgaaaat gtaaacagtc tctggtttat atagtaaaat gaaacaagaa tagggcaaat
     2041 cgatcaggac agtcaaatcg atttctaaca atgttttaga agttgaggtg tactattcta
     2101 gtttcaatct actatacaac ctcaaaactg tgttttgaac aacctgcggc tagcttctta
     2161 gtttgccctt tgattttcat tgagtataaa attgcagata aaacgataac aatcatagga
     2221 ctcagcagag tcaatgtagg tcgaagaata gccctcctaa tcgcttattt tatagcaaaa
     2281 tgaaatagaa actgaacatt ttgttgagga aggtaaatca attcctcaca atgtttgaga
     2341 aagaagggag gactattcca acttcaaccc actataaagc agacttacaa gatagggaac
     2401 ccatctccga taatatatag tagaatgaaa actgcacaat ttgattggag aattcaaacc
     2461 aatttctaac aatgttttag aaacaagggt ctattatttc aactgcaacc tactatagcc
     2521 cattgaagct ggaatagccc actgagactt ctaaaccact gctggagagg agtttgttta
     2581 gagtttcttt catttcccta aaaaatcaaa aagagagaac cagtctgatc ctctcttact
     2641 tatagatggt gctcactcaa atgttaaagg agctatttct tagagataaa ggaatttgaa
     2701 tacagctact gccgcaattg ctgctgcgat aggtgctact actggtaccc aagaatacca
     2761 ccattttgaa tcgcctttat gctcaccaag aactgatttt ggaaggaaag catgaaggag
     2821 acgtggtccc aagtcacggg ctgggttcaa ggcaggtcct gtaggtcctc caagtgatgt
     2881 taccaaagcc ataacgagga atccaagtgc caagtgagcc acagaaagtc ctgaagcagt
     2941 gtgtggagcc acctgtgctt taatagccaa gtcagaaaaa tcaactgttt gtcctgcttc
     3001 tattgccttt tgtttcatga attgaagcac ttcagcacca aagaagtttt tagtcaaacc
     3061 aagagctgca aagaacaaaa caaatgaacc aacaaactca ttaatcaaac cattgacagt
     3121 tgctgcatag cgactttctt ttgtaccatg gtcaatactt gaaatagttg agaaagttcc
     3181 caagatgtta tttggttttt cagttttcaa gtagaatgga cggtatgttg ccacaactaa
     3241 ggcttggcca aagatagccc ccaagacttg cgcgataatg taaggtacca cttgtgccca
     3301 agggaaaaga ccgctaactg caagccctag agtgaaagca gggttgatgt gattcccaga
     3361 tacgttacca aacatcaagg ctgggatcat aacccccata ccataaccaa cagcgatgac
     3421 gatccagcca ctttggtgac ctttcgtacc tttaagttca acgttggcaa ctgcaccatt
     3481 cccaagaatg atcaaaatgg cagttcccaa aaattcagtg gcatacttca gtgcccatgt
     3541 gaaatccatt tgctagattc tccttaaaat tttttagata ttccttattt tatcaatttt
     3601 taccctattt agcaactgat ttctggaaat atttttaaaa aaataggatt catagtttcc
     3661 cagttcaacg tacttgtaag cgtttttatt cttcacgaaa gacctcattc tcaaaaccag
     3721 gaaaaagccc acatctgtga tcttttcctt gttcctagat tctaaaatct attatttttc
     3781 atcttctttt ttcttgaaga atcctaatcc tagaccagct aacaaggtca tgataccagc
     3841 actagccaag gtagcattag cttctgtacc tgtgtttggc aattcctctc tcttacctgt
     3901 ctcataagtc ggaacttctg ggtctggatt cactggagtt tcagtttttg gagtacctgg
     3961 gtctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4021 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4081 gtcaatctta ccagatacaa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4141 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4201 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4261 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4321 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4381 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4441 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4501 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4561 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4621 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4681 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4741 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4801 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctgagattag ttctgccaat
     4861 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     4921 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     4981 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5041 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5101 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5161 tccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5221 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5281 gcccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa aggtttggcg
     5341 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5401 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5461 attatcctta acatgatagg taattttctc ctggtataag agtcttcagt agtttatatg
     5521 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5581 tatctttatc agcctgtttc aagacattat tcaagtcatt tgctaaccta ttggttgtcc
     5641 tcactgtgaa agttttcttc cagtctgaat cacttttatt agacttagat atgctcatga
     5701 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5761 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     5821 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     5881 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     5941 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6001 atcgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6061 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6121 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6181 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6241 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6301 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6361 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6421 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6481 ctgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6541 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctgac tcttgttcct
     6601 taaagatcgt catctttttt taaagtgacc ttaatctgct ttaaagctgc ccatactgaa
     6661 ggaacagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6721 acaaaggctt tcaattcttc taaagggatc ttacgctttt tgacgactcg ctttttccgc
     6781 tctaagttcc tttgttcacg tctttctttt cccacgtgaa gagagttctg acgccaacac
     6841 caaaaaactt tggccgcctc gacatgtctg tgccctcctt tgatggaatc taatgctcct
     6901 tgtttaaaat cagtattata tgccatagct ttattagacc atgcttattt taaactaagc
     6961 aactatatca atgttttgtt atgagaagac ttactttttt tactgaaatt gaatttttcc
     7021 tagcctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     7081 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     7141 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     7201 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     7261 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     7321 tacaaaccgt atcaacatct acgttgttcg ccaagctact gaaggattgg ctcgtttgat
     7381 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     7441 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     7501 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     7561 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     7621 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     7681 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     7741 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     7801 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     7861 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     7921 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     7981 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     8041 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     8101 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     8161 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     8221 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     8281 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     8341 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     8401 acgtgataaa gatgccatcc aagccattct tgtcgttgct gaacttgctg cctactaccg
     8461 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     8521 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     8581 gattatggct aaattccgca acaatgctcc aaaagaatgg aacgcaacag ctatcactgt
     8641 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     8701 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     8761 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     8821 agaatcacaa gctaagattg ctaacatcga agcagaaatc aatgcatttg taaaataaag
     8881 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     8941 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     9001 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     9061 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     9121 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     9181 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgctatgg aatcccaact
     9241 gtaccaggtt ttgttcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     9301 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     9361 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     9421 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     9481 taacaatgtt ttagaaatca cagtgggcta ttccatatta aattatccag attcaatcgc
     9541 tattatcgtt ttcctagatt acaaaaaaac tgcgttttgc taatcaaaac gcagtctcag
     9601 ccactatttt atcttactgt ccttctttta cttctttggt tgctacatct tctccaaacc
     9661 atttttggct gatttcttgg aacttgccgt ccttgtaaag actagaaaaa gcttcattta
     9721 tcttcttaac caaggttgta tcttccttac gggctccaac cgcaaaagct tctgtttcta
     9781 gtccaactgt aaagacatta taatcgttta aaacaccttc tgcttctaaa taatagtttg
     9841 catagacacg gtcaatcaat agaccatcaa ttcgatcgtt tttcaaatca atcaaggctt
     9901 cattaaaggt ttggtattga ttcgcttcct tattagcgac aatattcttc aaaatttctg
     9961 gatttgcttc aaagtccgca taaccagatg aaccagcttg agctcctaat gtctttccag
    10021 tcatatcctt tgcagtcgtg ataccagatg atttcttcgt aaccaatacc tgctcattct
    10081 tcatatatga gttactgaaa gccacctttt cacggcgttc gtctgtagcg gaatagccat
    10141 tccaaatcag atcaatcgtt ccttttgtca attcagcttc tttcaaatcc caatcaatcg
    10201 gttgccaatt taccgtgatt ccgtattttt caaaaacagc tgtagctaaa tcaatatcaa
    10261 atcctgcata agaaccatct ttctgagcaa atcccattgg aacaaaagta ctatcaaatc
    10321 caatagtaat agacttgtta gactggtact ttgaccaatt atctccacta gtttcgctag
    10381 aatttttccc acaagctact aagaacaaag cagtcatcag actgactaat acaagcatcc
    10441 attttttcat ccatttttcc tcctatttag gttctacttt caataataca tctgcgatat
    10501 tttcagcaaa ctgcaaatca tgggtaacca caatctgggt catcccaagt tccctatttt
    10561 gcaagattag cttctccact tccaaacgta attctggatc cagggcagaa gttggttcat
    10621 cgtagccaat gatttctggg tcaatcatca tagcacgcgc caaagccacc cgctgctttt
    10681 gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc tcctagtcct aactgttcca
    10741 agagtccact cgccttcttc tcagcctctt cctgcttcat tcccatggtc ttcacaggcg
    10801 ataaggtcaa attgtccaga actgataaat gagggaacag ttgaaaatct tggaatacaa
    10861 atcccagtag attgcgcttc tgcaattcat ccagctctaa aggttgtcca ttataaaaga
    10921 tttgccctga atcaatggtt tcaagacctg caagcatacg taaaagagtt gtcttacctc
    10981 caccagaagg tccaacgata gccaggattt gcttttcagg aatacttaga ctgaaattag
    11041 acaggatttg tttgtctcca aagactttat tgatatttcg taattctaac atggcagcct
    11101 cctatctata ataactatac ttcttctcaa cttttttgga aataattgtc acaatcccaa
    11161 tcaaaatcaa ataaatggct cctgccaaga acataggaac tagactagca tcgcggttag
    11221 cagctgttcg actagccaag ataaggtctg aaattccgag agcatagacc aaagaagtat
    11281 ccttgaccaa actcataact tcattaaaga cactaggaag aacgatcttg gtcacttggg
    11341 gcaagataat atagcgcact ctgtcaaaag ggctaaactt caagaccttg gcggcctcat
    11401 actgtcctct tggaatagtg tcaattcccc cacggaaaat ttctgcaaag taagctgcat
    11461 agttgagaac aaaggcaata atagctgcag gaaggcggtc taaacgaatc ccaatacttg
    11521 ggagcacata atagataaaa atcagttgca agagtaaggg ggttcctcgc ataacccaga
    11581 tgtaaatgtt aatcagataa tggaggggct tccaatggac ttgcaaggca aaggcaatca
    11641 aaacgcccaa gggaatcgaa aatagcaaga ccagtgcaaa gacctgtaca gtcgtgctcg
    11701 caccattcag taaactcggt aatatctcaa ataaataaga catactgcac ctcctaaaag
    11761 taattgttcc tattatagca tgaataaaca agattaccaa gtatttttgt aaaaagattc
    11821 taccatatac aaataaaaac cgtagctatc aaaagagata aactacagtt ctatatgttt
    11881 aaacattctt acaatctctc aaacagttct tgcatttgca catcatctgg aaccagtttt
    11941 aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc ccaattcacg caagagatag
    12001 atatagtgtt ccagaaattc tggattgtcc ttcaaatctc ctatcaactc ttgataatgc
    12061 tcataagcag tatccaaatc gtccatttct tgataagaac gagcaatcat ccacttggtc
    12121 aaaagatttt ctgactcctc actctgcaag tctagaatat cctcataacg ctcctgctcc
    12181 agataaatag tggctaaacg aagcaagatt tcttctgtat cctcagcgtc ttcttttgca
    12241 gtaaggagat aattttctgc accactagca tcatgcaatt cataagaaaa ttgtgaagca
    12301 gctagcaaga ggcgagtttc aaagggattt ttctctaatc cttgcttagc gatacgcagg
    12361 gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt acccatactc atagccttca
    12421 aagtcaggag aaatggtatc aagctgctta aagtagaggg tggctttttg atattcttct
    12481 tgatcaaaat aaagactggc caactcaaaa gctgttaagt catcgtattc taactccagg
    12541 gctttttcta aaaactcagt agccgtttca aatttcccta actgagcata ggcaaagcca
    12601 attcgttgat aggtggaaat gcccgtttgc tcataaatcg agcgattatc taactgggca
    12661 taggcttgaa tagccgcttg gtaattttcc aactcactat ccaactctgc caaacccaat
    12721 atcaagagag aatcctctga gtaggtcaag gcctccaata atttctcacg tgccacatct
    12781 gtcaaacctt ccagctggta aaggtctgcc ttcagagcca aagacgagac ataccagtca
    12841 ctgtcagctt ggatttcctc aagataggta aaggcttctt ctatttgacc atcctcgcta
    12901 gcaattgcag ctagattaag atgaacctct ggaaaatcct ctacaatttt caggtaaatt
    12961 tccttggcct gaggatagaa accaatccct tcaagataag ttgccaactc atacagaaga
    13021 tcacttgaat cattttctaa agctttggcg aaataatgct cagccttagt taaatcttgc
    13081 tcctccaaag cctgtaacat ctgttgacta ttgttcactc ttgacttcct caccctctaa
    13141 ttcatataga ccactgacta ccttatacca ttcgaaaatg gctgaaatga caaccttagc
    13201 agaggcataa accggaatac caagtaaaac tccccagata ccaaacatag atcctgaagt
    13261 taacaaaaca aagagaacat taatagggtg gatgtttaat tgacttccca aaatcaatgg
    13321 agagacaaaa cggccttcaa tagtttgttc tacgataaag acaatcacta ctttcaaaag
    13381 catgactgga ccagcaatca aacccaatac tagagcagga agcatggcta gaaagctacc
    13441 aagataaggg accagattta aaataccagc agtaaccccc agcgtaaccg catagcgtag
    13501 accaataatc ttgaagaaga tgataaacat tactgctaca ataatagcca ctgtcacttg
    13561 ccctcgaaca tagttggaca actgttgatt cacatctgat aaaacttgtc caacaggttc
    13621 cttcaatttt cttggaatga attgggtcaa atagttacgc aagcctttcc catcacgcaa
    13681 gagataaaag agcatgaaag gaacgataat caaggcaaca atcacttgag aagctccgct
    13741 aataaaggca ctcacccagt tgactgcctg agatgaaacc ttacttgcca aaactgtagc
    13801 ctggctagaa aaattggtca aaacttgctc taattgaggt ctgaaatcat ctggcaggtg
    13861 ctgggctacc aatccattaa caatcctatc tatatcttct aagtaaacag gaacgtttct
    13921 tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg actgccaagc cccaaatgat
    13981 aaagagagcg atgataacaa agacaatagt gatagctata acacgattaa ccttatgctt
    14041 ctccatccaa tcaacaatag gattcaacaa ataatataac aaaccagaca aaatgactgg
    14101 caacatcaca actgctaaaa agtctaaaac aggtgaaaat agaaaactaa tcttacttaa
    14161 aataaaaaga ttcagtccca ataataaggt tactaaaaat accgtaattg ccttgttatc
    14221 taaaaaccac ttgaaaaacc aagataggct aaaatgtttc tctttttgct ccataaatac
    14281 ttcctttcta ttgttctctc attataccat ttttgaaaca aaataactct tttttaaagt
    14341 gcttacatct aattggatat ctttaattta cttgtttttg tgatataata gtcttatctt
    14401 tacacagagg tatagtaatg aaagaaactg tttattttgg aacttataca cgtcgtactt
    14461 ctcaagggat ttacaaggca gactttgata cagaaactgg tcagctttca aatctagaac
    14521 tttttgcagc tgagccaagt ccaacctacc ttgcctttga ccagcaccaa catttataca
    14581 ctgttggtag ccaagacgat aaggggggaa ttgcagccta tcaaactgac gggactgtgt
    14641 taaatcatgt tgttgaagaa ggagctcccc actgttatgt tgctgtcgat gaaaagcgtg
    14701 atttggttta cgcagccaac tatcacaagg gacaagtcct tgtttataaa cgccaggaag
    14761 atggtagtct tctacttagt gatatggatc aacacagtgg ccaaggtcca catgaaaatc
    14821 aagcttcccc ccatgttcac tatacagatt taacacctga ccactatcta gtgacctgcg
    14881 acttgggaac tgaccaagtc atcacctatg acctcgatca agaaggaaaa ttatctaagc
    14941 tctataccta tcacagcaag ccaggagcag gctcacgcca tatcattttc cataaccact
    15001 ataaaatcgc ttatctcatt tgtgaactca atagtactat cgaagtttta atctacgatg
    15061 gcgttggcga atttgaacgt atgcaggtca tttcaacttt accggaagct tacgaaggct
    15121 ttaatggaac cgctgctatt catctctcta aagacggtaa atacctctac gcttctaacc
    15181 gtggccatga ttctatcgca gtatatacca tccttgcgga cggtagctta gagttattag
    15241 aaatcgttcc aacgcatggt cagactccac gtgattttga tttgacaccc gaccaaaaat
    15301 ttctcattgt tgtccatcaa gactctgaca atgcaactgt ctttaaacgt aattgtgaca
    15361 atggtcgtct agcagaactc tccaacgact tccatgttcc cgaagcagtc tgcatccgtt
    15421 ttgctcctta aaacaccata aaaaatgaac ttggtatttt caagttcatt ttttcttata
    15481 gtctatttcc gacattaata cggttaatag cacgttgcaa agcaatctta gcacgacgtt
    15541 cttggtcaat caaatgtttg tcttgtgctt cttcaattgc acgttctgca cgaagtttgg
    15601 cacgttctgc acgactgata tcgatatcac gagcacgttc tgcagagtca gcgacgattg
    15661 tgatcatatc attggcaatt tcaataacac caccgtttac tgcaatccag ttcacgtgat
    15721 ctttatcatc gatacgtttt acctttactt catcaactgc taaaaccgca atcatatttt
    15781 catgtcgtgg caagatcccc atctcaccat ccagagttcg aaccgataca tagctggcat
    15841 ggtgatcata gacgagacca tctggtgtca cgatctggac agttaactga gccatagttc
    15901 acctcttaaa atcccatttt ttcagctttt gcaatcacat cttcgataga acctacacca
    15961 cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa ggatttcctt aaagccacgt
    16021 acagtttcag caactggaac ataagaacct ggctgaccag taaattgttc cgcaacattg
    16081 aagttttgtg acaagaagaa ctggatacga cgggcgcgag caaccaaggt cttttcttca
    16141 tcagaaagtt catccatacc aaggatagca atgatatctt gcaattcatg gtaacgttga
    16201 aggacacgtt ttacttcagc agcaactgca tagtgctctt ctccaacgat ttcaggtgcc
    16261 aaggcacgtg agcttgaagc aagtgggtca acggctgggt agatacccaa ttgtaccaac
    16321 ttacgttcca agtttgttgt tgaatccaag tgagcgaagg ctgttgctgg cgctgggtca
    16381 gtatagtcat ccgctggcac atagatagcc tggatagagg ttacagaacc cttcttggtt
    16441 gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa gtgttggttg gtaaccaacg
    16501 gctgatggca tacgacccaa aagggcagat acttctgaac cagcctgagt gaaacggaag
    16561 atattatcga taaagagaag cacgtcttgg ccttccacat cacggaagta ttcagcgatt
    16621 gtcaaaccag taagggcaac acgcatacgt gctcctggtg gctcattcat ctgaccaaag
    16681 accatggctg ttttctcgat aacgcctgat tctttcattt cccagtaaag gtcattcccc
    16741 tcacgagtac gttccccaac accagcaaat actgaaatac caccgtgctc ttgggcaatg
    16801 ttgtgaatca attcttggat taagacagtt ttaccaactc cggcaccacc gaaaagtcca
    16861 actttaccac ctttaaggta aggggcaaga aggtcaataa ccttgatccc tgtttcaagg
    16921 atttcagaag aggtagacaa ctcatcaaaa gttggagctt ttttatgaat tggctgacgc
    16981 tctgcgtctt ctgtaaaagg agcttccaag tcaatggtat ctcccaaaac gttgaagaca
    17041 cgtcccaaag tttctttacc tactggtaca gagattggac gacctgtgtc caatacttcc
    17101 attccacgag tcaacccatc tgttgattcc atggcgatag tacgaaccat accatctcct
    17161 aactccaagg ctacttcaag gacgattttt gtttttcttt cgtcattttt gtagacgaca
    17221 agtgcattgt taatctcagg aagtttttcc cctgctgcaa acaaaacgtc tacaacggga
    17281 ccgataacct gagcaatttt acctgaactc atctccttct cctattctat ataagatact
    17341 gtcggttcct agctcaacta ggtcctaagt tcattttcat acgagctgga ctagagccta
    17401 ttctaaggca ctagcacctg ctacgatttc tgtaatttct tgtgtaatcg ccgcctgtct
    17461 ggcacggtta tactgaattg tcaaatcatt gatgactttc ttagcattat ctgtcgctgt
    17521 ttgcatggct gtcatacccg cagcattctc agctgtcttg gcatctataa tggcaccgta
    17581 aatcatactt tctgcaaact gaggcaacaa ctgctccaga atttcttctc ggctggtttc
    17641 caattcaaaa gtcaagctgt actcttcatc cgcttcattt ggatccaagt caacaatcgg
    17701 aagcatttgt tccacacgca tttgactggt tagcgtattg acatggtggt tgtagcaaac
    17761 ataaagctca tcaaagagtt cattttggta catttcaaca gtttttgaaa taatcttacg
    17821 aacttgatca aagctaggtt ggtctgccaa gccacgtaat tcataaagtg gttgaatacc
    17881 gcgagcctta aagaaatcag ctcccatccc accgatacag atcatttcaa aacctttacc
    17941 gtctgggtgg tattcttctt tcaactccat aacagctttc aaaatagagg aattataacc
    18001 tccaaccaaa ccgcggtctg aagtgataac gatatagcct gtcttcttca cagaacggct
    18061 aatcaacatc ggattagttg aagcaccagc tccattacca tgaaggatat ctgtcaaaag
    18121 tttacgcact ttctgagcgt aaacttggaa gttgcgagca gcttcttcag agcgacctag
    18181 cttagcagcc gataccattt gcatggcatt agtgatttga ctcgtatttt ttgttgaggc
    18241 gatttttgtt ttaatatcat ttagagatac tgccatctga cacctctatt cttattggaa
    18301 gctagattga ttgagaaact ctgtaatcgc agcatccaag actgcttctt ctggcaagtc
    18361 ttttgtatca cgaatggttt ccaaaatctc tggatgttga gcatcaaaga aggcatggaa
    18421 ctcttcctcg aaacgaacaa tatcatctac tggaacagta tccaagaaac catgtgtcaa
    18481 agcataaaga atggttactt gtttctcaac aggtaatggt ttgtgaacag gttgtttcaa
    18541 gacctcaacg gtacgacgtc cacggttcaa cttagcctgt gttgctgcgt ccaagtcaga
    18601 accaaactta gtaaaggctt ccaactcacg gtatgaagca aggtcgatac gaagtgtacc
    18661 agcaaccttc ttcatggctt tgatttgtgc agaaccacct acacgagata cagatgaacc
    18721 cgcatcgatg gctggacgaa tacctgcatt gaagaggcca tcgccaagga agatttgtcc
    18781 atcagtgata gaaatcacgt tggttgcgat ataggctgag atatctcctg cttgtgtctc
    18841 gataaatggt agggctgtaa ttgatccacc accaagttca tcagaaactt tagctgagcg
    18901 ctcaagcaaa cggctgtgga gatagaaaac atcccctggg aaggcttcac gacctggagg
    18961 acgacgaagc aagagcgaca gttcacgata agctaccgct tgttttgata gatcatcgta
    19021 tacaatcaaa acatgcttac cttgatacat aaattcttcc gccatagcga ccccagtata
    19081 aggagctagg aagagcaatg gagatggttg tgaagcagag gctgtcacaa cgattgtgta
    19141 gtccaaggca ccgtactgac gaagtgtttc tacttgcgta cgaactgttg attctttttg
    19201 tccaatcgcg acgtagatac agatcatatc ttgatctttt tggttcaaga ttgtatcaat
    19261 cgcaatggtt gttttccctg tctgacggtc accgataatc aactcacgtt gaccacgacc
    19321 aatcggtaca agggcgtcaa tagctttcaa accagtttgc aatggttctg aaacagactt
    19381 acgttgcata acaccaggag ctggtgcttc tactggacga gttttatcag tgtggatttc
    19441 tccaagaccg tcaactggac gaccaagcgg atccacaaca cgaccaatca gactttcacc
    19501 tacagggact tccatgattt tccctgtacg gcggattgta tcgccttcac ggatatctgt
    19561 aaagtcacct aggatgataa taccaacgtc tgttgactcc aagttttgag ccataccata
    19621 agagccgttt tcaaaattca acaactctcc actcatgaca ttttcaaggc cgtgagcacg
    19681 cgcgataccg tccccgatat aggttacaac acctgtttca gtcacatcaa aattgggttt
    19741 gaaattttca atttgttgct taattaaagc gctgatttct tgtgcgttaa ttgccaaaag
    19801 aacaccactt tctatttcaa attttcttta acaactttaa gttgttgttt aatactcaca
    19861 tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa tgagactttc atcgatttgt
    19921 tcttttacac tccttacttt cagagacatt tttttctcaa tcaaagggag caaacgagtc
    19981 ttctgttcat cagttagagg atgagcagac gtaatcgtca cttcaaatcg atttgtttct
    20041 ttttcaagtc ggttcaagca atctacaagc acatcataaa aaagatttgc tctgtgattg
    20101 taggccagaa cctggataaa gttttgtaat aaaggcgaca cagaatcttg gaaaaaagca
    20161 attgtttttt ccttatccga ctcgtctact gccacttgtt ttaaaaaaga aggcagacct
    20221 gttttttcaa caacttgctt gatttgagtc aagtctgaaa agatacggtc ttcttctcct
    20281 ttttcaagta ccaattggac aaaaggcatg ctgtattttt caattacctt tactgttttc
    20341 ttgtccatta agcttctcct agctgatcga tatactgatc aatgagtgct ttatgggcat
    20401 gactgtcaag gttttgtgag atgattttac cagctaagct gatggtcaga tctgcgacct
    20461 cacccttaac actctgtaaa gcttctactt tattttgagc aatttcttga ttggcttttt
    20521 cttttaagtg tcctgcttct agtttagcat ctgctaagat attagcctta ctttgctcag
    20581 ctgtttcctt tgcattttca atgattgtct tagcttcttt acggctacca gccaattcat
    20641 cttcgcgttt ttgagccaat acttctgctt tttgacgggc ttcttcagct ctgtcaatat
    20701 ctgaagcaat tttttcagct ctttcttcga aaatgcctgt aatattagac catgcaaatt
    20761 ttttaatcaa gactagcaaa agaataaaag agccagtgat taaaataaaa ttaccaatta
    20821 attcacctac tgttacgtgc atcagttact cctttctatt cctcttcaat attaatctta
    20881 ttccctaaat acacagatgt caaaagagta aaaacataag cttggatgca ggaaataaag
    20941 acagaaaatg cagtccaagc caaattagct ccaaaggcta ctggatacca ataaatagct
    21001 tggtgggaaa gaagaagtaa caaactcgtc atgacctctc ctgcaaagat attcccaaaa
    21061 atccgcaaag ccaaagataa gaagtttgta aattcttcca agatattcat cggtatgaca
    21121 aaaacaggac tcataaaaga ttttatactt tttttaaatc cacgacgacg aacgctttct
    21181 atatgtgtca acaaaatgac aagaaaagat aaggttaagt catactgtaa attagcggtt
    21241 ggcgaactcc accagttagt cccatcgatc gtttgaagct ttgtcattaa gccaaggtta
    21301 ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga gtgaataatc tttcatgtag
    21361 cgcgaaccaa tattaggttc tgtaaatcca ataacaaagt catagacata ctcaagtaca
    21421 ttttgctttc ctttgggttt caaggtcata ttgcggcttg cccaataaat aaagacaaaa
    21481 ataactccca caatcaacaa agtcatggct aacatagtca gattgaagat aacaggacca
    21541 atagagatga ttggattaat actttcttcc atctaaaatc ctcccttttc ttctcgttcc
    21601 atgtatttat ttgataataa atgagaagac aagagttaca aagaaagttc cttcaataaa
    21661 ggcaacacct aaaaacatca aactacgaaa ctcagaaagc atatctggtt ggcgtgctac
    21721 tgatttaaac agtccattca tcaataaacc ttcaccgaca gatacgccca tacaggcaat
    21781 acataagcct aaaaatgtta aattcataac aaattctcct ttaaaataaa atttacttac
    21841 ttagtgtagt cctaaaattt aaatttgtca acttttaacc gctattggaa gcgtttaata
    21901 aaaattattt ccattttgct aaatttcaag ttcaagttag ccatccaaaa gtcttctctg
    21961 ggtgacttgt agtccaagca ttttttag
//
LOCUS       DBEJZJ010000033        20849 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000033 DBEJZJ010000000
VERSION     DBEJZJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.33"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..339
                     /locus_tag="ACL3R8_001574"
     CDS             <1..339
                     /locus_tag="ACL3R8_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR1314428.1"
                     /translation="NCLSETTDKNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKK
                     PIPKHLPPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAIN
                     VLDKVMKKIF"
     gene            complement(477..1781)
                     /gene="eno"
                     /locus_tag="ACL3R8_001575"
     CDS             complement(477..1781)
                     /gene="eno"
                     /locus_tag="ACL3R8_001575"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR1314429.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1945..2391
                     /locus_tag="ACL3R8_001576"
     CDS             1945..2391
                     /locus_tag="ACL3R8_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR1314430.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2388..3503)
                     /locus_tag="ACL3R8_001577"
     CDS             complement(2388..3503)
                     /locus_tag="ACL3R8_001577"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR1314431.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3512..3841)
                     /locus_tag="ACL3R8_001578"
     CDS             complement(3512..3841)
                     /locus_tag="ACL3R8_001578"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR1314432.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3786..4157)
                     /locus_tag="ACL3R8_001579"
     CDS             complement(3786..4157)
                     /locus_tag="ACL3R8_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR1314433.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4216..5649)
                     /gene="glgA"
                     /locus_tag="ACL3R8_001580"
     CDS             complement(4216..5649)
                     /gene="glgA"
                     /locus_tag="ACL3R8_001580"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR1314434.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5646..6785)
                     /gene="glgD"
                     /locus_tag="ACL3R8_001581"
     CDS             complement(5646..6785)
                     /gene="glgD"
                     /locus_tag="ACL3R8_001581"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR1314435.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6775..7917)
                     /locus_tag="ACL3R8_001582"
     CDS             complement(6775..7917)
                     /locus_tag="ACL3R8_001582"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR1314436.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7907..9835)
                     /gene="glgB"
                     /locus_tag="ACL3R8_001583"
     CDS             complement(7907..9835)
                     /gene="glgB"
                     /locus_tag="ACL3R8_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR1314437.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10211..11635)
                     /locus_tag="ACL3R8_001584"
     CDS             complement(10211..11635)
                     /locus_tag="ACL3R8_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR1314438.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12180..14459)
                     /gene="pulA"
                     /locus_tag="ACL3R8_001585"
     CDS             complement(12180..14459)
                     /gene="pulA"
                     /locus_tag="ACL3R8_001585"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR1314439.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(14571..16529)
                     /gene="ligA"
                     /locus_tag="ACL3R8_001586"
     CDS             complement(14571..16529)
                     /gene="ligA"
                     /locus_tag="ACL3R8_001586"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR1314440.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(16622..17800)
                     /locus_tag="ACL3R8_001587"
     CDS             complement(16622..17800)
                     /locus_tag="ACL3R8_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR1314441.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(17880..18743)
                     /locus_tag="ACL3R8_001588"
     CDS             complement(17880..18743)
                     /locus_tag="ACL3R8_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR1314442.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(18746..20647)
                     /locus_tag="ACL3R8_001589"
     CDS             complement(18746..20647)
                     /locus_tag="ACL3R8_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR1314443.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         6293 a         4591 c         3708 g         6257 t
ORIGIN      
        1 aattgtctaa gcgaaacaac cgataagaat tggcacaaaa gcgaccgtat ttttgttacc
       61 aatataggaa aaccagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa
      121 cgccttaaaa aaccaattcc caaacatctg ccccctcaca tcttcagaca caccactatt
      181 agcatcttat cagaaaataa aattccttta aaaacaatca cggacagggt tggtcattcc
      241 gactctgaag tcactacttc catctacacc caggtcacaa agaatatgaa agatgaagca
      301 atcaatgtac tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgt
      361 cctctaaata caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat
      421 caacggccga acttttgaat ttcatggttc gggataaaat agttcactga actattttat
      481 tttttaaggt tgtagaatga tttcaatcca cgatattcag ctacttcacc aagttggtct
      541 tcgatacgaa gcaattggtt gtatttagcg atgcggtctg tacgtgaaag tgaaccagtc
      601 ttgatttgtc ctgcgttagt tgcaactgca atatcagcga ttgttgaatc ttcagtttca
      661 cctgaacggt gtgatacaac agcagtgtaa ccagcttctt tagccatttc gatagcttca
      721 aaagtttcag taagagtacc gatttggtta actttgataa ggattgagtt agcagcacct
      781 tcttggatac cacgtgcaag gtagtcagtg tttgttacga agaagtcgtc accaacaagt
      841 tgtactttct taccaagacg ttcagtaaga gctttccaac catcccagtc gttttcatcc
      901 ataccatctt caatagtgat gattgggtat ttgttaacca attcttcaag gtagtcgatt
      961 tgttctgcag atgtacgaac agcagcacct tcaccttcaa atttagtgta gtcgtaaact
     1021 ttacgttctt tatcgtagaa ttctgatgaa gcacagtcaa atccgataaa tacgtcttta
     1081 cctggtacat atccagcagc ttcaatcgca gcaaggatag tttcaacacc atcttcagtt
     1141 ccttcgaaac gaggagcgaa tccaccttcg tcacctacgg cagtttccaa accacgtgat
     1201 ttaaggattt tcttaagagc gtggaagatt tcagcaccgt aacgaagggc ttctttaaat
     1261 gttggcgcac caactggcaa gatcatgaac tcttggaaag cgattggagc gtcagagtga
     1321 gaaccaccgt tgatgatgtt catcattgga gttggaagaa ctttagtgtt gaatccacca
     1381 agatagctgt aaagtgggat ttcaaggtag tcagcagcag cacgagctac agcgatagac
     1441 acaccgagga ttgcattcgc acccaattta cctttgttag gagtaccgtc aagtgcgatc
     1501 atagcacggt caatagcttg ttgatcacgt acatcgtagc caatgatagc ttcagcaatg
     1561 atgttgttta cgttgtcaac agctttttgt gtaccaagac caccgtaacg agatttgtca
     1621 ccgtcgcgaa gttcaactgc ttcgtgttca ccagtagaag ctcctgatgg aaccatacca
     1681 cgtccgaaag cacctgattc agtgtaaact tctacttcaa gtgttgggtt accgcgtgag
     1741 tctaggactt cgcgagcgta aacatcagta ataattgaca ttttttactc tccttatgag
     1801 ttaaattttt tacacctcta taatacctta aaacccctcc tttttcaaga aaaaacgtta
     1861 tctttgtgca acttttcctt aactttataa agtaatcgct ttcttttgtc tgttttattc
     1921 taacttttat gatatactgt tttcatgaca gatttatcaa aacaattact tgaaaaagct
     1981 catggtgggt taaaaataaa tccggatgag caaagacgct atcttggtac ttttgaggaa
     2041 agagttcttg gatatgtaga tattgacaca gcaaatagcc ctcagttaga aaaaggcttt
     2101 ttatttattt tagaaaacct tcaggaaaaa gcagagccac tatttgtgaa gatttcacca
     2161 actatcgaat ttgataagca agttttctac ttaaaagaag caaaagaaac tgatagtcaa
     2221 gccaccatag tatctgaaga gcatattact tctccttttg gcctggttat tcatagcaat
     2281 gcaccagttc aagtagaaga aaaagacctt cgacttgctt ttccaaaact ttgggaagtt
     2341 aaaaaggaag aaccagccaa aacatcctta tggaagaaat ggtttagcta aatcttgcac
     2401 atatttaata agtgcccaat attggcagcc gtgcgctcca gatagagact ggcatttttc
     2461 aaactatctt ctaaaggttc acttttctcc aaaatagaaa agacagcttg gatattttca
     2521 aatggtaggg gaggtaaatc ttcagcaaga ctaccgcaaa tagcaataac aggaactcca
     2581 acaggggttc tttttgcaac acctataggc gctttcccag caaagctttg actgtcaagt
     2641 cttccttctc caacaacaac caagtcagca tctgaaactt tcttatcaaa gttgattaag
     2701 tccaagcagg tatcaattcc agacacgata cttgcctgag caaaggcaca caaaccacca
     2761 gcaaggcctc cacctgctcc tgctccttta atttctaatg ttgcaggtga gaatttttca
     2821 taaaaatctt ggatcgcctg atctacgact gcaaacatag tcggatgtag acctttttga
     2881 ttgccaaaag tgtaagtcgc accttgataa ccacataagg gactcacgac atctgctaaa
     2941 atatgaattt gaacaccttc aggaatttta tagcgatttt ctgttgaaac agaagctaag
     3001 tttaataagg attgaccgga agcaggcaag acatttccat ccctatcata aaattgataa
     3061 cctaaaccag cagcaatccc cagtcctcca tcattactgg ccgtgccacc aacaccgata
     3121 taaatatctt taatcccttt agaaatgaga tggagaatca actctccaat accacaagtt
     3181 tggatttgaa gtggatttcg tttctctagc ggaatttttc caagaccaac caagtcagct
     3241 acttcaaata gtgccagttc ccctttttga aaatagcgca tggcttcttt ttgtccaaaa
     3301 gggtctgtca cttggatcca tttttctttt aggtcaagag aatgtcggat agcatctaca
     3361 gtaccttctc ccccatcacc aacagggcag aggagacatt ctacatctgc tatcgattgt
     3421 tggaagcctc tttttattgc ttcagctacc tgttgagctg tcaagctttc cttaaacgaa
     3481 tccggtgcaa ttacaatctt catattttcc ctcattctaa acagtcaatc aaaggaagaa
     3541 cttctaaaaa atccctcttg tcaacatgat gtggtatttc ttttttgagc acttctttgg
     3601 cacaaaaggc gattcctaac tccgccgact tcaacattaa tagattattg accccatcac
     3661 cgattgccac cgttctttct ttagaaagtt ttagtttctt tctccatttt tccagagttt
     3721 cttttttgac ctggggactt ataatttgtc caactaattt tcctgttaaa agaccttctt
     3781 tgacttcaag ctggttggca gtgaaatagg caataccaag ggattttgct aatctctcca
     3841 actattggtg taaatccacc agacaccaga ccaactagga tgccattctt ttggagaata
     3901 gagatgaact ctgggacatt tagcgataga tgaattgagt tgaagacgtt atcaaagacc
     3961 aaaataggaa gaccttccaa caaggacact ctttttctta aactgctttc aaagaccaac
     4021 tctcctcgca ttgctcgact tgtaatctgc gaaatttccg cctcatgacc tgcctctctc
     4081 cctaaaagat caatcacttc ttctaggatt aaggttccat ctacatccaa aacacacaag
     4141 ccttttactt gagacatcag ttctcctctc taaacagcct aaaaatcgta tgaagtcatc
     4201 atacgatttt atctattaat taactaaact atggtacaag tcaaggtatg acttgcaggc
     4261 tgtatcccat gagaagtcac tctccatagc ttgtttttgt aggtttctcc aaatgtctgg
     4321 atggtttcta tacaagtcca atgctgtttg gaaagtccaa tttaaccaat aaggagatag
     4381 attgtcaaag ctaaagccag taccgcttcc ttcgattgga ttgaaagcgc gaactgtatc
     4441 tcgcaagcct ccaacttcat ggaccaatgg caaggttcca taacgcatag ccatcatttg
     4501 agacaagcca cacggttcaa aacgacttgg catgaggaag aggtcacaag cagcgtagat
     4561 ttcctgagca agtttgacat caaaagtgat atttgttgat agcttgtctg ggtaaatctg
     4621 agcaaaccat gagaaagctc cttcaaaggc tggatcgcca gttcccaaaa gaacaatctg
     4681 aacatcttct tgcaagatat ggtgaagact ttcgaccacc acatcaaaac ctttttgacg
     4741 tgtcaaacga gaaacaattc ccaccagtgg aacgtctgct ctaacaggca agccaactct
     4801 ttcttgcaat tttgccttat ttttggcttt cccagacaaa tcttcctgat tgaaatgata
     4861 gtctaaaaga gcatccgtct gaggattata aagatcagca tcaatcccat tcacgatacc
     4921 agatacttta ccagactcca ttttaagaat ctgatccaaa ttacatccaa actgactagt
     4981 cataatttca tgagcatagc taggtgaaac ggttgaaaca cggttcgcat agagaatacc
     5041 tgccttcatc cagttcagac agttgttcca tcgaagggtg ccatcagcgt aacgttcaag
     5101 gccaactcca aacaaatcac ccaacattcc ttctgaaaat tgtccttgga attctaaatt
     5161 atgaatggtt aaaactgttt caatgtcctc ataggcttga atccaacggt atttttcctt
     5221 caacaagaaa ggaatcatag ctgtatggta gtcatgaaca tggagaagat caggaataaa
     5281 gtcaatcctt tccatagcct caatggcagc cagttggaaa aaggcaaagc gttctccgtc
     5341 atcaaaatca ccgtaaacat gaccacggaa gaaataatat tgattgtcaa taaagtagaa
     5401 ggttacacca tttaatactg ttttcttaat tccacaatac tgtctgcgcc aaccaacgct
     5461 cacctcaaaa tgaagcacat cttcaatctg atttccaaat ttagcctcta ccatatcata
     5521 gtagggtaaa atcactgcaa cttcgtgccc agcttttacc agtgattttg gaagagcgcc
     5581 aatgacgtct cccaaaccac ctgtttttga aaaaggtgca ccctctgctg ctacaaataa
     5641 aattttcatg aatgaatatc ctctgttact ttagcacctt tcttaaccac aactggatgt
     5701 tctgcagttc ctcgaatcac aacaccaggc tcaacttcaa cccctttgtc caagatagca
     5761 tattcgacct gagccccttt tccaataaca acacgaggga agagcaggct atctttaacc
     5821 aagctatcct tatggacatg aatattacgt gatagaacag aattagctac ttgaccttca
     5881 ataatactac cagaggcaaa ctgagaagtg cttaccttag atgtattagc atagtaagtt
     5941 ggctcttcgt ttttgacctt tgtataaatc ttttggtttg gtgagaaaag agaatagaat
     6001 ttttgtgatt caagcatatc gatattcgct tgataataag atttaacaga gtgaatattg
     6061 gctagatagc ccgtgtactc gtaggcgaaa gctccctctt ttacagccaa atcccgtaaa
     6121 acatagcgca atttctttgg atgttctttt ttagcttctt cttccaagtg ttcaatcaac
     6181 caaggtgtat caacgacaaa gatatctgta gacatattga acatttcagc tgttgacttg
     6241 ctatcaaaga gtttatgaga aagaacatgg tctgtttcat ctacatccaa gattgcattt
     6301 acttctgaaa tatctttctt agctagtttt ttataaacta cagtgatagg ctcttttgtt
     6361 gtactatgta ggtggaaaac ttggttcaaa tcaatgttaa taagaacatc gcagttgagg
     6421 gcaaccgttt ggtttgagcc agaacgtttc aaataagtaa gaagctgttg gtagtattct
     6481 tttccaactg tactactttc tacacgggta ttgtaaattc ctagatagta atgactaaga
     6541 agggttgata agccccactc gcgtcctgaa cgaatatggt caaatactga gctgatatta
     6601 tcctgctgga aaataccaaa gacactacga acacctgcat tagcaaggct tgaaagtggg
     6661 aagtcaatca aacgatattt cccaccaaat ggcaaacttg ctactggacg gtggtccgtc
     6721 aatgtcgaca tattgtgaaa accaactgta tttcctaaaa tggcagaata tttatcaatc
     6781 ttcatctgtt gctaccccca ctacttcatt atatcctaca acttgtactt catctgttcc
     6841 atcaatttcg acaccgtcag aaataatcgc accttcacca ataatggcac gtttaatctt
     6901 agctccttga ccaatgatag ctccactcat gataactgaa tcaaggactt ccgctccttc
     6961 gcgaacttgc gcgcctgttg aaaggataga atgtttaaca gctccatcaa cgaaacatcc
     7021 gtctacaact aatgagtctt ccacatgagc atttgccccg aggaagtttg gtggtgaaat
     7081 caagtttctt gagtaaatct tccattgacg gttacgacta tccaaggcat tttctggaga
     7141 aatatactcc atgttcgctt cccaaagtga ctcaatagta ccaacatctt tccaataacc
     7201 actaaattcg taagcataaa cactttcacc tgactcaagg taatttggaa tgacattttt
     7261 accaaagtct gacatgccaa ccttgctctt ttcagcagcg actaacatat tacgaaggcg
     7321 ttgccaatca aaaatgtaga ttcccataga agcttttgta gatttaggtt gagctggttt
     7381 ttcttcaaat tcaacaatac gattgttagc atctgtgttc atgataccaa aacggcttgc
     7441 ttctttaaga gggacgtcta aaactgctac tgtcaagctg gcattattat ccttatgaga
     7501 ctggagcata tcatcatagt ccattttgta gatgtggtcc ccagacaaaa tcaagacata
     7561 ctcaggattg acactgtcga tatagtcgat attttggtaa atagcgtgac tagttccctc
     7621 aaaccaacga tttccttcac ttgcagaata aggttgaaga atagagacgc ctgaattaat
     7681 accgtctagt ccccagcttg aaccattccc aatatggttg ttgagagcaa gtggttgata
     7741 ctgtgtaacg accccaacat tatgaatccc tgagttggca cagtttgata gggcaaagtc
     7801 aatgatacgg tagcgcccac caaattgcac agctggtttt gcgatgcttt gagtgagttt
     7861 accgagacga gttccttgcc caccagcaag aatcaaagct aacattttat ttttcatttt
     7921 ctactccttt ttggttttta tttgtgacgg ttttagtaga tttcaagcga cgtttgattt
     7981 tccatacact tgctcccata gccggtagag taaaggttaa ggtctgctca taatctttcc
     8041 ataggccttc ttgcgtttga acagtttgat tatgttcttt ccaaacgcct ccccactctt
     8101 ccaactcagt attccatact tcttcgtaaa ttcctgcaac gggtagtccg attgtaaaat
     8161 ctttccgctc aacaggtacc atgttaaaga tacagactaa catttctccc tttttaccct
     8221 tacgaataaa ggaaagaaca ctctggtctc gattatccgc atcaatgatt tcaataccat
     8281 catagctggt atcgatttcc cacagacagc gatgatcttt gtaaaactgg tttagctgag
     8341 aagtgaaata cttcatctta gcattcattg ggtcttctag gttagaccat tccaactgtt
     8401 cttcagattt ccattctagg aattgaccgt attcgctacc catgaagagc aatttcttac
     8461 cagggtgaca aatttggtac gtatagagat tgcgcaagcc tgcgaattga ttgtaacgat
     8521 ctccccacat cttatgcatc atactcttct tgccatgaac cacttcatcg tgcgagaatg
     8581 gcaagagata attctccttg aaaacataca taaagctgaa agtcaccagg ttaaagtcat
     8641 atttacgata aatcggatct tcttcgtaga aacggaggat atcattcatc cagcccatgt
     8701 tccatttgta gtcaaatcct agaccaccaa tctctttcat tcccgtaatc ttggtcgcag
     8761 acgaactttc ttctgcaatc atcatcacat ctggatattc taacttaata acttcattca
     8821 agcgttgaag aaaataataa ccttcatagt taagatttcc gccatcttta ttaggtgtcc
     8881 atggagcatt atcatagtcc aaatagagca tgttgctaac agcatccaca cgaataccat
     8941 ccaaatgata gacatcaatc caatgcttaa tgcaagaaat taagaaggac tggacttcat
     9001 tttttccaag gtcaaaatta agggcacccc aaccatggtt atgagcctta ttatggtctt
     9061 ggtattcaaa agtcggtgtc ccatcataat aggctaaggc atcatcgttg atggtaaagt
     9121 gacctggtac ccagtccaca ataaccccaa tattatgggt atgacactcc tcgacaaaat
     9181 cttgaaactc ctctggtctg ccataagcat gctctaaagc gaagtaaccc ataagctgat
     9241 acccccaact caagcccaaa ggatgggaca tcaagggcat aaactcaata tgagtatagt
     9301 tcatttcaac gagataagga atgagttcat ccttgagctg ggcaaaacta taaggactgc
     9361 catcaggatt tctcttccaa gagccagcat gaacctcgta aatattgaca ggacgttcaa
     9421 caaagcccca acgttttctt cgtgccagcc aaagtccatc cctccatttc ttatcaggaa
     9481 gctctgttac gattgcccct gttcctggac gagcctcata cctgacagca aaagggtcaa
     9541 tcttcatcag ttgatgacca ttttgacgtg tgacatgata tttgtaaata tgcccttctt
     9601 gagccatatt ggtaaagact tcccagaccc caaagtcatt tcttaccatt ggaatctgat
     9661 tttcaatcca gttggtaaaa tcaccaacca agtgaacagc ctgagcatta ggtgcccaaa
     9721 cacggaaggt atagccatgc tctccattta gttcttccct atgtgctcct agataatgtt
     9781 ggagataaaa attttcaccc gtcataaagg tttttaatgc ttctctatta tccatatact
     9841 ccccttctcc tgtaagcgtt ttctatgttt ttattatact acctttttag agaagattca
     9901 agtaaattac tatacttctt taattatttt gaaaatctac aacaagttca cttactcgtt
     9961 caattgtaaa tcaatatttt ttcaaaaaat tgcgaaaacg cctttctttt tctactatag
    10021 tgaaatgaaa taaaacatgc gcaaatcgat caggacagtc aaatcgattt ctaacaatgt
    10081 tttagaagta gagctgtact attctagttt caatatacta taataccaaa aagttcgtat
    10141 tttttctata attattatta ttttatagca aaaaaataaa accaggaaaa caatttcctg
    10201 attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc gcttcaatgc
    10261 tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat gggaaattat
    10321 ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt ttttcagcaa
    10381 tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg aattcagatt
    10441 cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt aaaacaggac
    10501 caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa agcactggcc
    10561 agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt tcttgtgcat
    10621 cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt gtaatatcag
    10681 cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc aaagtagcta
    10741 atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa cgttgtcctg
    10801 agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct gcatcttcta
    10861 gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata ccagctaaac
    10921 gaccaatacg ttctccaata ggggttgaac ctgtaaagtt gatgaagttg acttctttgt
    10981 gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg aaaacacctg
    11041 ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg gaaccttgtg
    11101 ttggtggctt aaacatgacc acattccctg caatcaaggc aggtgcaatt ttagaagcag
    11161 ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact ggttcacgac
    11221 ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc attgcttgtc
    11281 cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta cgcactactt
    11341 ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta ccaatttttt
    11401 ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt tcaattgctg
    11461 ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca tcagcttcag
    11521 tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa taaatcgtaa
    11581 tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt gtcaaattct
    11641 tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaatc acaacccttt
    11701 ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac tcaataaaaa
    11761 taaaaaaaat ccactacatc aaggcgagac taatgtggtt tgaagaaatt ttcgaagagc
    11821 gtgaatgagt atcatctata gtaaaataaa aaaactgaac aatttggttg gggacagtca
    11881 aaccaatttc tcacaatgtt ttagaaacaa gggtgtgcta ttccaatttc aggctactat
    11941 aactgtcata gattgctgaa acaaagtcta ggtaaaagtc ttcataataa aaagaccccc
    12001 tatcaagtgt tcaaaaactt tgataggagg tcttgttttg tgaaaatatt tatcaaattt
    12061 tctatacaag tgagctgtta gccaggttct ttctattctt tcaatttcaa tgaatggatt
    12121 ttttaccaat actcataact gggaatttgt ctgtgtaaaa atagcgagat agatggtatt
    12181 tataaaacac tcaagacagc tagactaata tcatttaaaa cattatcttc ttttgagcga
    12241 ctgttggtta ccaacatagc taaatttcct gcattttcaa attgataggg ttctgattta
    12301 gcattcacaa ctaccaagag gtgttctttg ccgtgaactt catagataag gcagccgcta
    12361 tgttcaatcg cagaatgcac aaagacatga tggtaaattt catcatagct agagtaagaa
    12421 aaggcaccag tttttgtctt caatcggatg acttgacgga taaactcaat actgtcttga
    12481 cgctcattaa tcaagttcca gttcacttgg ttcacactgt caggagcatt atagctattc
    12541 atcgcacgct ctctatcatc atgggtcaac tcaccatttt caccagtcgc aaccagtttg
    12601 gtacgaccaa attcttgacc gatttccata aaggccatcc cctgcatgag cagattcatg
    12661 gctgtggcag tttcgacctt gcgcatgatt tgctctgaac tttggtctgg atgaagggtt
    12721 gccaataaat cgtgaagatt gtaattgtca tgggcttcta catagttaag cacctgattt
    12781 ggatgtgtat aggttcctaa ttcacgactt cctaggattg ctttagctag aattggctct
    12841 gtcgcagcac cactgacaaa acctgacttg atagcaccat aaacttctcc ccctttgaca
    12901 gcatcgcgct gattgtcatt aaagaaacca atatttggca tctggtaggc attgtccttc
    12961 ttggccttat cataaggggt aagacctgtt cccatatccc atccttctcc atagaggata
    13021 atgttggagt cgatttcatc caagctttga cgaatcatct gcatggtctt gacatcatga
    13081 atccccatca agtcaaaacg gaagccgtca atattatatt cctgcaccca gtatagaaga
    13141 gaatcaatca tatacttgcg aaacatttcg tgttcactgg ctgtttcatt tccaacaccc
    13201 gttccattct ggaaggtacc atctggattc atacgataat agtaatcagg gactgttgtt
    13261 tggaatggtg catcaacaac tgagaaggta tggttataga ctacatccat aatgactcca
    13321 atacccgcat cgtgataagc ttgaaccatc accttcaaat cacgaatgac ctgagctgga
    13381 tcatctggat tagttgaaaa actagtttct ggcgcgttat agttttgtgg atcataaccc
    13441 cagttgtagg ttacatttcc atcctcatcg tattctttat gacggtctgc aattggttgc
    13501 aattgaacat aattgtagcc cagcttcttg atgtaatcaa aagcagttga ctggccgtat
    13561 tggttaactg ttccagcctg agcagcaccc aagaaagttc ctcgaagatg ttcatctaca
    13621 cccgatgtag gtgatttagt caaatcacga atgtgcattt cacagataac tgccttacat
    13681 ggattttcca agcgccaagt agcctccgaa ccgtgcttaa cctcgaagtt ttcaacttgc
    13741 ttttctacat ggctcagaat agctgaacgt ttgccatcag ggctggtcgc gattgtataa
    13801 ggatcacgtg tcagtgtttg gtgatgaggg aattggactt gatactgata agtcttacct
    13861 accaaatctt cttcaacatc caaactccag acaccgattg tattgtcctt atgattataa
    13921 gagtagctat tgcctctttt catctcaaaa gtcttccaaa cgggtgcatc attagcagct
    13981 gattcataaa cgacaacttg cacttctgtc gctgtaggtg accagaggga aaaatgagcc
    14041 tgattgtcct ctacacggca acccaattct ccttggtaac cccaatgatg atcaaaacta
    14101 gcactgttaa tggccttatc aaaggcaaaa ggattttgat ttttatagaa aggactggca
    14161 atagcaggat tttcagagta ataaatccta tcatcgcctt ccaaaatcca gacctctgtc
    14221 aataggggat agtgattaaa acggatagaa tattctttac tagtttgacc tgtatgaacc
    14281 acaaaattca agctttctat aacatgtgaa cttgggtgtt caaagctaaa taaagctcca
    14341 aaataatctt ctttgtaggt tagcaaatca attcgttgat cctgactttt tacaaaggag
    14401 caagtgtcat attctccatt cttacgatgg taatgaatgc gcatagggta gttatacatt
    14461 ttttattttt cctttttact ttgtttctat ttcactaata aatttttgtc aatctcgtct
    14521 caattaacag acatagtcat attctctaaa ctctgttttt aaacgatcca ttacaaactt
    14581 tctagccatg cctcatctct gacctggata ccaagttctt gtgctttttg cagtttactt
    14641 ccagcgtctg cacctaccac gacgaggtcg gtctttttag aaacactacc tgtcactttg
    14701 gcacccagac tttcgagttt acttttagct tctgagcgct tgagtcgttc caattttcct
    14761 gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta ctaccgtctg tcctttatag
    14821 tccagattga ccccagtttc tttcaattct ctgagcagaa tttcagagcc ttctgtcgca
    14881 aaataagtct gaagactttt ggcaatcacg ccacctagac tttcaatact agccacttcc
    14941 tctgaatctg cctgatacag attttcaatt gaatggaaat attgaagtaa aagctgacta
    15001 gccttgcttc cgacatgacg aattcccaaa ccaaataaga gcttctcggc agaattttcc
    15061 tttgatgctt ggatagcctg atacagttta gcagcggact tttccttaac cccctctaaa
    15121 aggaggaaat cctcttcttg caaacgataa atatccgcca catccttgac taaattagca
    15181 gcaaaaagct tctcaacaat agatggacca aggcctgtaa tattcatagc atcacgagaa
    15241 gcaaagtgaa tcaagccttc catgatttga gcagggcaac gcggattgat acaacgtagg
    15301 gccacttcat cttcaaagtg caacaagtca gagttacaac ttggacagtt tgtagggata
    15361 tctagttttt cttcagaaac ccgtttggac tctaccacac gtaaaacggc agggatgatg
    15421 tcaccagcct tatatacaat gaccgtatcg tcttttcgga tatctttttc agcaatataa
    15481 tctacattgt gcagggtcgc acggctaaca gtcgtaccgg caagttgtac tggtgttaga
    15541 ttagcagttg gagttacaac accggtacgg ccaactgtcc agtcaactga taagagttga
    15601 gcttcttttt cttcagcagg gaacttgtag gctactgccc actttggagc cttaacggta
    15661 aaaccaagtt cttcttgact tgctaggtcg ttgaccttga ttaccactcc atcaatatcg
    15721 taaggcagat tttcccgttc ctgtcctact tcttggataa aattccagat ttcatctatg
    15781 ttttcagcca agattcgctt aggattgacc acaaaaccta gttgttctag gtacttcaaa
    15841 cccttttctt ggctatcacg agttgaaggg ctggcttctt gatagagaaa cgttgcaaga
    15901 ttacgcttgg caactactgc tgtatccaac tgacgcagag ttcctgctgc cgcattacga
    15961 ggattagcaa attcaggctc tccattttct tggcgcactt ggttaacttg gtcaaaggaa
    16021 gcgcgtggca tgtaacattc cccacgaact gtgatatcta gttcttctgg caaagtcaaa
    16081 gggatgtcct taacacgctt gaggttttct gtgatatttt caccaattga accatctcca
    16141 cgtgttaccc cagcaaccaa aatccccttt tcataagtca gcgagataga taagccatcg
    16201 attttcagct cacaaatata ggtcggatga gccacttcct tacgaacacg cgcatcaaaa
    16261 gcatctagct cctcacgtga aaaagcatcc tgcaaactat aaagaggata ctgatgactg
    16321 tatttttcaa aaccatctaa aaccttgcca ccaacacgat gagtcggact gtctgctagc
    16381 acttgctctg gataagcagt ttctaactcg accaactcac ggtaaaggcg gtcatactca
    16441 ctgtctgaaa ccgagggatt atcgctggta tagtactcag tcgcatagcg attgagcaaa
    16501 gcgactaact cattcattct tttattcata agaccatttt accataaaac aagccctcct
    16561 cacaaacgag aaggacggaa aaaacactta gtttgaaatt atttttgaaa ctcaagcaac
    16621 cttatatcaa tttttcaaaa tgagttcgaa cataaataaa cgatatacaa gacaagatga
    16681 taacaccact tccaattatc aggaaagaag agagatgtac acttggcaag actgtcataa
    16741 atccttttgc aataggcata aatagaatag ctaaggtaaa aattgtactc agtactctcc
    16801 caagaaattc gctctcaacc ttggtttgta cttgagtaaa aaagtgaata ttaaaaatcg
    16861 tcataaacaa ttcacaaact aaatttccag aaaaggaaag aaaagttgga agtggtaatc
    16921 ccatcataaa aactccgaca cctgtcaaag ccagtaaaat caaaagatta taaatattag
    16981 ctttaatttt actagctaga agagccccaa tgatggaacc aatagccccc atagttaaaa
    17041 tacttgcata ggctccttct gatccgtaaa gctgattcga aaagggaagt agaaattcaa
    17101 aagctgcaaa aaagaaatta acgctggaag ctaccagcaa aaggaagaaa atttcttgct
    17161 gatgccagat atagtgtaac ccatccttga tatctacaaa aatatctctc ccagtaaaag
    17221 cctttttctc ttgaactttt gcttcctctt ttggaaggaa agccactaga acaaaagcaa
    17281 tgaaaaaagt cagcgagtct agcagtagcg tcatatggag acttgcaaac tgtaaaacaa
    17341 ggaaggaaag aacaggagag ctaacaccta caacctgcaa aaccagctct aggcgagaat
    17401 tatagatcac aatctcatct ttctccacca cttcagttat gatagcttta ttggctgtgc
    17461 gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac aatcaaagcg ccaatcatcc
    17521 agctatcatt ccttatgaaa gaaatagcca gacaaagaat cccacaaaca agatctgccg
    17581 tcattaaaat cttacgacga gaaaaacggt ctgaaataac tccgccaaag ggattgacga
    17641 gaatagatgt gacgagctca gaaatctgat acattcctaa aactgtctgt cctatagtcc
    17701 ccatagaagc caaccagaca ctatttccat aatcatagag catatttccc attttattga
    17761 tagccccacg gctaatcaac tgcactgcat agcgattcat attaaagctc ctctcaaatt
    17821 ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt tttcccttat ttgggaaaat
    17881 taacttttga caaatttttc gtagtgttcc tgataatagg ctacttgctc tggaagacct
    17941 aacacatcaa aaatatgtat ggcctcttgc atctgcttac agccttcttt acactgtcct
    18001 ttttgatata aggcaaaacc ttttaaataa tggaaaacat tacgctcata aagcttaata
    18061 cctttgtcaa taatcttctc tgtataagcc tcaaaatagt tggcattata aaaagaagaa
    18121 tgctctaaac aatgctggta acaattgagg gccaaaatca aaactaatct cttatggcga
    18181 ctaatctctt ggtaaaattc ctccctctcc ataacttctc taccaatccg agtgacatag
    18241 tctacatcgt agaaactata gaggttaccg aaaagaatca actcatacat ggtccattct
    18301 tctgttttga agagataatc tgctacctta tccaaatcat cctgcttcat atcataactc
    18361 gcatctcttt gacaaatcag accttgtagc aaaatccagt tcagctcaaa ataaagggga
    18421 gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa gcttttgaaa acctgcaata
    18481 tcgtttgaat agtaaagtgg gataatctgt gccatcatag acacatgttc atgattgtga
    18541 aaattccttg ccttatccat gaaattttcg attgttacat gaatgttatc caaaatctca
    18601 aagaaacggg agactgccag gtcagactcc ccaagctcaa agcgagataa ctgagaggta
    18661 gagcaggatt cgcctgctgc ttcctttaaa gaataatttc cacttgttcg aaattcacga
    18721 aatacttttc caagatgttc catctttaca cctgatctga taattcttcc cactcaagca
    18781 tagcttcttc ctgacgatgg ctgattttgt ccagctcagc ctgtaattcc atgagtttgt
    18841 cggcatcgtt tgtttccaac atttgttcag aaatggcttg gctttgactt tctagctctt
    18901 caatttcagc ttctagactt tcgatttgtc gcatgagttt gcgaacttct ttttgacttt
    18961 ctttctgggc ctgatagtca ttgactggac ttgcttcctt tgcttgattg ctagttgaag
    19021 cttcctcagt ctgactcatt tctgctgttg ctttcttctc aacatagtag tcgtaatctc
    19081 caaggtagag agttgaacca ttctcagaca attccaaaac atgagttgcc acacgattga
    19141 taaagtaacg atcatgactg acaaaaagca aggtaccatc aaagtcaatc aaagcatttt
    19201 ccaacacttc cttgctatca atatccaagt ggttggtcgg ctcgtcaagg atcaggaagt
    19261 tgttgttttc catagacaat ttagctaaaa gcaaacgagc tttttcgcca ccagatagca
    19321 tgccgactga ttttttaaca tcatctcctg agaaaaggaa ggctccaaga cggttgcgga
    19381 tttcaacttc tggtgtcagt ttgaaatcat tccagagttc atccagcacc gtattacttg
    19441 gtgtcagctt gctttgggtt tggtcatagt aaccaacctc aacattagcg ccaaagcgct
    19501 tttcaccttt gataaaagga atctggtcca caatagactt gataaaggtt gacttgccga
    19561 taccatttgg accaacgata gcgacagcat tcatcttacg aagatctagg ttgataggtt
    19621 gtgacaagac ttccccgtca taaccaatag cagtattttc aacagtcaaa acaacattgc
    19681 ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt cttgccagct tcaggcttgt
    19741 ccaaacgctc cattttttct agttgtttac ggcgagattg agcacgttta gtcgttgaag
    19801 cacgaactag attgcgattg acaaagtctt ccagagcagc gatttccttc tgttgctttt
    19861 catagttttt tgcctcagta actagctttt gctccttcaa ttcgacaaaa cgagagtaat
    19921 tccccacata gcgatccaag gaatgcttgg tcaaatctag cgtaattgtc gcaaccttgt
    19981 ccaagaaata acggtcgtgg ctgacgataa tgagggcacc gctatagttt accaagtaat
    20041 tctctagcca ggcgatggtt tcaatatcca agtggttagt tggctcgtcc aagaccaaga
    20101 gattgggctt ttcaaggagc attttggcaa gtgccaaacg agtattttga ccaccagaaa
    20161 gctcagcaat tttcatctgc cacatagact cgtcaaactt gaatccattc aaaatcgctc
    20221 gaatatcagc ttcataggta aagccacctg cttggcgaaa attctcagat aagcggtcat
    20281 aatctgacat cagtttatcc aaatcctcac cagacttttc acccatctcc agctccatct
    20341 gacgcagttg tctctccgtc cgacgcaaat tattaaagac atgaagcatt tcatcgtaga
    20401 tggtattttc agactcaaaa cggctatctt gggctaggta agacagagaa atatcttttt
    20461 tcttattgat ttctccgcta gttggctcct cttctccaac taaaatcttc aaaagagtag
    20521 acttacctgc accatttttc ccaacaaggg caatccgatc tcgttcatca acctgcaggt
    20581 tgatattatc gaaaagaacc tctcctgcaa aagaacgttc aattttatta gcttgtaaaa
    20641 taatcataag agtagtatag catgtttccc taaggcattc aagataatcg taagtctttt
    20701 agtacaactt ttataacata aaataaacta aattatgtat attttatatt agattcttca
    20761 ctatcttgtt ggattttcta accagctaat cttgtttcaa atagttatcg cacaagccta
    20821 ttatttaatt cttttcatta tttacgtac
//
LOCUS       DBEJZJ010000034        20797 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000034 DBEJZJ010000000
VERSION     DBEJZJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.34"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="ACL3R8_001590"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="ACL3R8_001590"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR1314444.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="ACL3R8_001591"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="ACL3R8_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR1314445.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="ACL3R8_001592"
     CDS             2279..2812
                     /locus_tag="ACL3R8_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR1314446.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3170..3601)
                     /locus_tag="ACL3R8_001593"
                     /pseudo
     CDS             complement(3170..3601)
                     /locus_tag="ACL3R8_001593"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3693..4025)
                     /locus_tag="ACL3R8_001594"
     CDS             complement(3693..4025)
                     /locus_tag="ACL3R8_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1314447.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(4038..4811)
                     /locus_tag="ACL3R8_001595"
     CDS             complement(4038..4811)
                     /locus_tag="ACL3R8_001595"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1314448.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGIGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5259..6014)
                     /locus_tag="ACL3R8_001596"
                     /pseudo
     CDS             complement(5259..6014)
                     /locus_tag="ACL3R8_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(6152..7774)
                     /gene="groL"
                     /locus_tag="ACL3R8_001597"
     CDS             complement(6152..7774)
                     /gene="groL"
                     /locus_tag="ACL3R8_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR1314449.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7790..8074)
                     /gene="groES"
                     /locus_tag="ACL3R8_001598"
     CDS             complement(7790..8074)
                     /gene="groES"
                     /locus_tag="ACL3R8_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR1314450.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKAAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8344..8739)
                     /locus_tag="ACL3R8_001599"
     CDS             complement(8344..8739)
                     /locus_tag="ACL3R8_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR1314451.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(8817..9578)
                     /locus_tag="ACL3R8_001600"
     CDS             complement(8817..9578)
                     /locus_tag="ACL3R8_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR1314452.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(9611..10237)
                     /gene="ytpR"
                     /locus_tag="ACL3R8_001601"
     CDS             complement(9611..10237)
                     /gene="ytpR"
                     /locus_tag="ACL3R8_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR1314453.1"
                     /translation="MIFTYNKEYVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(10253..10570)
                     /locus_tag="ACL3R8_001602"
     CDS             complement(10253..10570)
                     /locus_tag="ACL3R8_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR1314454.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(10567..10866)
                     /locus_tag="ACL3R8_001603"
     CDS             complement(10567..10866)
                     /locus_tag="ACL3R8_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR1314455.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDLFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFIYENEDLVYEEEVL"
     gene            complement(11064..11144)
                     /locus_tag="ACL3R8_001604"
     CDS             complement(11064..11144)
                     /locus_tag="ACL3R8_001604"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314456.1"
                     /translation="MASSGKMLRNTYTPDSYYVGNLGAWQ"
     gene            complement(11151..11342)
                     /locus_tag="ACL3R8_001605"
     CDS             complement(11151..11342)
                     /locus_tag="ACL3R8_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR1314457.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(11503..12177)
                     /locus_tag="ACL3R8_001606"
     CDS             complement(11503..12177)
                     /locus_tag="ACL3R8_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314458.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(12183..12629)
                     /locus_tag="ACL3R8_001607"
     CDS             complement(12183..12629)
                     /locus_tag="ACL3R8_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR1314459.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(12731..13246)
                     /locus_tag="ACL3R8_001608"
     CDS             complement(12731..13246)
                     /locus_tag="ACL3R8_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR1314460.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(13243..13605)
                     /locus_tag="ACL3R8_001609"
     CDS             complement(13243..13605)
                     /locus_tag="ACL3R8_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HGR1314461.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(13671..14702)
                     /locus_tag="ACL3R8_001610"
     CDS             complement(13671..14702)
                     /locus_tag="ACL3R8_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314462.1"
                     /translation="MDFLLMGALFIVLPQTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATVHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(14709..15530)
                     /locus_tag="ACL3R8_001611"
     CDS             complement(14709..15530)
                     /locus_tag="ACL3R8_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314463.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(15547..16017)
                     /locus_tag="ACL3R8_001612"
     CDS             complement(15547..16017)
                     /locus_tag="ACL3R8_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR1314464.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(16141..16857)
                     /locus_tag="ACL3R8_001613"
     CDS             complement(16141..16857)
                     /locus_tag="ACL3R8_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1314465.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(17738..19147)
                     /gene="ply"
                     /locus_tag="ACL3R8_001614"
     CDS             complement(17738..19147)
                     /gene="ply"
                     /locus_tag="ACL3R8_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR1314466.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(19158..19568)
                     /locus_tag="ACL3R8_001615"
     CDS             complement(19158..19568)
                     /locus_tag="ACL3R8_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314467.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(19561..20169)
                     /locus_tag="ACL3R8_001616"
     CDS             complement(19561..20169)
                     /locus_tag="ACL3R8_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314468.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(20182..20640)
                     /locus_tag="ACL3R8_001617"
     CDS             complement(20182..20640)
                     /locus_tag="ACL3R8_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR1314469.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
BASE COUNT         6244 a         4525 c         3617 g         6411 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 cgaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatt
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaataccaa tcaactttca ggagacaagg gtccttatgt gctgactcaa
     1801 aaactagctc aaaaagggat ttcaaaatct actatagaag agaacttgaa agaatttgat
     1861 ttttctgaag ttgctcaacg tgtagctaat aaactattga aaaaatatga gggaaaactt
     1921 ccatctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tctgatgcta aaattgcctt tgacgactta gatagccaag ttgaccaaga aacgactcaa
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgctcgaaa gtatgaagga
     2101 tacgaactga agcagcgttt aactcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 ccaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 caacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggg gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gaccttgttt ttttggtagt ataaaataaa ttgtgtaaac
     2881 acaaaaagga ataaatccat tatagcagag ttacaacaca ttactagaaa gagatttatg
     2941 cagaattcgt aaaatatata aaacaaatag atatactatt attttttaat gtctttattc
     3001 ctagtaagtt tacaacaaac ttatatcgtt taatacaaaa aatacgaaaa tgattagtat
     3061 aaaaaataca ggtcaacttc gtatcaaaaa catttttttg tatttccaca tagcatcaat
     3121 catttagtac aatattttaa aaacaatatc ttaacagaga aaatgatatt taatctatca
     3181 gctcatttaa tcgtttttga aaatataaag caatactttt agattcaata aactcaaaat
     3241 attttatgac attgtccatt tgtttaattc cagattcttt agattctgtc aggtatattt
     3301 tatatccttc tacaaatttg aatgtagatt tttcaaaaac ttttgtgtca tcttttaata
     3361 atttttgtaa tttcatttca aagtagtctg catatattag atgtgaattt tcaaggcaac
     3421 agaaccaaaa atttaaacaa gctgacacaa ctaaatttct attcttgccg attttttcgt
     3481 aataatgtgt acgctctagt atttcttttc cgaccatgta aatataatct atttcaaaaa
     3541 gatgatataa attaccaatc agcgttatct cataggactc ccatcgttcc ttctggaata
     3601 aatagtcata tactaaattt agatcatctc tactaactac atgattacaa tctagctgat
     3661 ttcataatcc ctgaaccata attgtattta ttttatgagt ttttcccact cttctcaaaa
     3721 agtttttgtt gcttattttt tattacctcc aatcctttaa tattcaaact ataaaaattt
     3781 ggagataaat taaccaaaaa atcatcacgc tccgatcttt tataatgttc taagtgatta
     3841 caaaaattct ctatcgaaac attgatattt gataataatt caaaaaatgt tgaaagagaa
     3901 atttcatttt ctcccctttc aaatctagaa agttgagatt ttgatataga atcagctgca
     3961 gcatactcta aagaatatcc gtttaatttt ctaaaatatc gaaaagcttc tccgtaattt
     4021 ttcacacttt cattccctta actttctttt cgagcgataa acataccata ttctttagga
     4081 atgatcaaca taccattatt aaactcactt tccaatcttt tacgtattat ttcctcttct
     4141 agtgaaccta tttctgaaat tcctttaaac gattggatgt atttaactag gtcatctata
     4201 ctagttacct gtaactcatc atcatagagt aatgtatcga cagagttaaa atacctactc
     4261 aggtaccttt taccattttg taaagtaaac gttctatttt ctaaatcttg attaacctca
     4321 tctttaaata aacttgccaa ataatttaca actccatttt caccaaatgt agcacagtaa
     4381 aaaattcctc cggtttttaa gaccctattc acctcagaga gagctttagg aatatcattc
     4441 acatgatgta gaagcatatt agcaataaca atatcaaaag tttcattctc aaaagaaatc
     4501 ttttgaatat ccattatctc ataattgaca ttgtttctat ttccaatcac tgacttcgtt
     4561 gattttacca tatctttaga aaaatctgta acaatcaact gcttcatttt atctatagaa
     4621 tcactattac ttttccacaa ttctcctata ccacatccca attctagaac ctttacttca
     4681 tcagtgattt ggtagttaga aaatatccaa ttattaaatc ccaatttatt ttttgaatac
     4741 ttcttatgca attctactcg aatatcaaga ttatcatgac ttttatattg ttcaattact
     4801 ttatcaatca ttttaaatga cctccactct ataatttggc attatatcac aagaataaag
     4861 atagtgttaa ataagttgta taaatgcaaa aaaggaataa atccattata gcagagttac
     4921 aacacattac tagaaagaga tttattccta cgactcagtt tggcatgctt aacttcctaa
     4981 ctcaaaaaca aagcatcgat taatttatcc gttcttcttt tgaaacagat ttgaactgat
     5041 aattgctcgt tttaatttaa gaagctcttt tgagcaaaac ttcatttttt taagagtcca
     5101 acaatttctg tctatcgctt ttctactagc aaaaaaaact accttgaggc aagttttcat
     5161 ttatatatct aatttcgtaa tagtatagta aaatgaaata aggacagtca aatcgatttc
     5221 taacaatgtt ttagaagtaa aggtgtacta ttctagtttc aatctactat aaatttgata
     5281 tgagaatagt ctttctcaac atccttaccc aacaagaatg ctgtagcgtc cttcttaact
     5341 tgaaccaggt caatattctg ggcttgggct gcatagacgc agccacaata acattgacga
     5401 tagatatcat actcctcaca catctctact gaacgtttgt agccttgatt tttcttgaaa
     5461 tcgttgggaa gatagtgggt cgtgtaaatt ttttgcacat cgattccgat gctgttgatg
     5521 gtttgagaat tcttatgagg actgatggtc aaggctgaac caaagtagtc aaagcccaag
     5581 tccatagcca cttgcgctgt tttatccagt cggtagtcaa aacaaacctt gcaacggtcg
     5641 ccaccttcgg gctcctcctc tagtccccta actagttttc ggtattaatt gggttcgtag
     5701 ggagcttcta ggtactgaac cgtatttcct gtccgctcat taaaatcact aacaaatttc
     5761 ttggtgacat agacccgctt atggtattct accttgggat ggatattaga attggcaaaa
     5821 tagatggtca catctgcata cttggtcaaa tattctagtg tataggtact acaaggggca
     5881 cagcaaacat gcacgagaat ggttggccgt tgctcatttt tctaccatac ttctaccatt
     5941 ttctgcatga cacggtcata attaatcttc tgattggggg gcatcttgca cagaatttct
     6001 tctacatcga tcatgttctt ctcctttttc tagtcttatt ttatcatata agttaggaga
     6061 gctcaaatca atttagaagt gaatattata aaaagaaggg ttagtcattc cctccttttg
     6121 tgttttttat aagttgtttt ctatagaaag cttacatcat cccgcccatc atacttggat
     6181 ccattgctgg agctggggct actggttctg gtttattggc tacgactgct tctgttgtca
     6241 aaatcaagct tgctacagat gctgcatttt gtagggctga acgactcact ttaactggat
     6301 caatgatacc ttgatcaatc atgttaaccc actcgccagt tgctgcgttg aatcctatac
     6361 caagctcagc atttttcaaa cgatcgataa cgatagatcc ttcaaatcct gcattgtgag
     6421 caatttgacg aacgggttct tccaaagcac ggagaacaat attacgtcct gttgcttcat
     6481 ctcctgtcaa ttccaaggta gcaacagctg gaatcacatt ggcaagagct gttccaccac
     6541 ctgcaacaat accttcttca acagctgcac gagtagcgtt gagggcatct tcaatgcgga
     6601 gtttcatttc tttcaactca gtttcagttg cggctccgac cttaataacc gctacaccac
     6661 ctgacaattt ggccaagcgt tcttgcaatt tttcacggtc aaattcagaa gttgtagttt
     6721 cgatttgaga cttgataacc gcaacacggt gagaaatcgc ttcaggattt cctgcacctt
     6781 ctacaataac cgtgctatct ttgtccacgg tcactctcgc tgcttgacca agagcttcaa
     6841 ttgtcgcatc tttcaactca agaccaaggt cttctgtgat aactgttccg cctgttaaga
     6901 tggcgatatc ttcaagcatg gctttgcgac ggtcaccaaa accaggtgcc ttgactgcta
     6961 ctacgttgaa ggttccacga atcttgttca aaacaagagt tggaagagcc tcgccatcca
     7021 catcatccgc aataatcaag agtggacgat tgctttggag aatgctttcc aaaagtggca
     7081 agatttcttg gatattagaa attttcttgt ctgtaatcaa aatgtacgga ttttcaaggt
     7141 cagccaccat tttttcgcta tcagtcacca tgtactgtga aaggtaacca cggtcaaact
     7201 gcattccttc tacgacttca agctctgttt ccataccacg tgactcttcg atggtgatga
     7261 caccgtcttt gccaactttt tccattgctt cagagatgta ctcaccaact ttttcagaac
     7321 gagaagatac ggctgcaact tgagcgatag cttctttatt ggcaacaggg atggcgttgt
     7381 ttttcaaagc ttcaactgct gcggcaactg ccgtttcaat cccacgacga ataccgattg
     7441 gatttgcacc tgctgtgacg tttttgattc cttcacggac gattgcttgg gtcaaaacag
     7501 ttgcagttgt agttccatca cctgcgatat cattggtttt tgaagctact tctgatacca
     7561 atttggcacc catattttca aaatggtctt ccaattcgat ttctttggca atggtcacac
     7621 cgtcattggt aatcaaaggt gaaccgaatg acttttcaag aacgacattg cgaccttttg
     7681 gtcccaaggt tactttaaca gtgtctgcaa ggatatcgac accacgaacc atggctgaac
     7741 gggcatctga tgaaaattta atttcttttg acatacttac tttctccttc tattcctcaa
     7801 tgattgccaa aatgttagct tcgcctacga tgatgtactt ttcatcgcca tctttgacat
     7861 caagacctgc gtgggcttca actaagacac gatctccagt tttaacactt ggagcaacca
     7921 agtcaccgtt caaggtacga acaccttgtc cagtagccac aacttgagct gctttggttt
     7981 tttcttgggc tgagcctgca aggacaaagc ccccaacggt ttgttctttt tcttctattt
     8041 ttaagaccac acggtcccct aatggtttca acatctgatt tcctccataa tgagatagat
     8101 attattagca ctctttgaac ttgagtgcta attcataatt ctattgtatc acttggtcag
     8161 aaatagtcaa gaaaaaagtc tgactttctc aagataaaaa gcctgagacc aactcagact
     8221 ttttaatgtt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc
     8281 tcaaagcatt gctttgatgt tgtggataaa gctaacgtgg tttgaagaga ttttcgaaga
     8341 gtattaaaat ggcaattctt cctcttccaa gaccaaatct gccaaatctt ggcctgcatt
     8401 attttcacgc atggcacgtt gagcacgact ttctaagagt tggaatcctg tcacaaggac
     8461 ttcggttaca tagttcatct gaccattttt ctcaaagcga cgggtacgca attctccatc
     8521 aacggaaatg agactacctt tggttgcgta gcttgccaaa gtttctgcta gcctgcccca
     8581 taggaccata ttgacaaaat cagcttcacg ttcaccgttt tggtctttgt aacgacggtt
     8641 gacagcgata gttgctcgcg ctaccgactt gtcattgttg gttttgtgca attctggtgt
     8701 agacgttaaa cgcccaatca agataacttt attatacata ttttcttcct cctacttatc
     8761 tattcgtagg aaatcaaaaa aagttacaga aatttgtaac ttttcgagga aatttcttat
     8821 tttttatgaa tcatgaaacc tgtcgcctgt tgattggcca taatggtcat atctgtaatc
     8881 tgaacacggc gaggctgact ggtcacatag actactgtgt ctgcaatatc ctgagcttgc
     8941 aaggcttcta ttccttggta aacggacgca gcccgctctt tatcaccatg aaaacgaaca
     9001 gttgagaaat ctgtttcgac aatcccaggc tgaatggttg tcaccttgat atccgttgcg
     9061 atggtatcaa ttcgcagtcc atccgaaaag gtcttaaccg ctgccttggt agctgagtaa
     9121 acagcggcac cagcataggc gtagattcct gcggttgacc ccatattgat aacgtgacct
     9181 tgattgactt ttatcattgc tggcaagaaa cagcgagtaa ccgccatcag acctttaaca
     9241 ttggtatcca acatggtcaa catatccaac tcctcatagt cttgataggg agccaagtca
     9301 agagccagtc cggcgttgtt gaccaagata tcaatcctcc ctatcgtttc tagaatatca
     9361 gagcaaacag tcttcaccat gaccatatcc gtcacatcta gtggaaaagt ccagacagtt
     9421 tgatttggaa agcttactgc aaactccgac ttgaggattt ctaatctgtc tatccgtcgt
     9481 cctgttagaa cgacatcctc accctgctcc agataagcac gcgcaatcgc ttcaccgatt
     9541 cctgaggttg ctcccgtaat cactacattt tttgccatct tatttccttc tatcagatgc
     9601 tgacaagttc ctaggcagtc cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt
     9661 cttctgataa ttcaagcacc ccacgttttt gcggagcatt tggcagatgc aattcacgag
     9721 gactgcacat cataccaaaa ctcttttcac cacgaagttc acctgggaaa atgagattcc
     9781 cttttggcat catagctcca ggaagcgcga caatggtttt caaccccaca cgcgcattgg
     9841 gagctcctgc aacgatttgt acagtcttat cacttgcgac tgcaacttgg cagatgttga
     9901 ggtggtcact atctggatgg gctaccatct caacaatttc accgacaaca aacttaggtt
     9961 ccttatcatt aacaatttct tctgtaaaac cttccgcctg caactcttgg ttcaaacgag
    10021 cgacttgctc atctgtcaaa aagacttgac cgcgctctgc aatttcaaat aaacttgaaa
    10081 cttcgaaaat attccaagcc actgtttccc cattatcttt gagaaaaaca cgggctacct
    10141 tgcctttgcg ctccacatcc agtttggcat ctccgctatt tttcacgatg accataagga
    10201 catcaccgac atattctttg ttatacgtaa aaatcattgt ttcctttttc tcctatttca
    10261 atcctgctaa aaaatcattg atttgttgct tgcttttacg gtcgcgattg acaaaacgac
    10321 cgatttcctt gtccttttct agaacaacaa ggctaggaat tccgtaaaca tcccagagtt
    10381 tggccaaatc catatactga tctcggtcca ttcgaataaa ggtgaactct ggattggtct
    10441 cctcaatctc tggtaaggca ggataaatat aacgacaatc gccacaccag tctgccacaa
    10501 aaaggaagac cttcttgccc gctttttcca ctaaagatgc taattcttct aaacttgctg
    10561 gctgtatcat aagacttcct cctcatagac taggtcttca ttttcataga taaaggtata
    10621 atgacggcca tcctcaaaaa tgacgccacc aaccaagctc tccagactgc tttcgtaaac
    10681 ttgaacatag agggtcgcaa tttcccccat gtcggaaaaa aggtctcgca caatctctgt
    10741 caactcttcc tgagtcttca tgagcttacg gtcatctgca acttttttcg tagcaagagc
    10801 aaggcttccg atacctagca gagccaagcc tgccatccac atttttttag ctttcatacc
    10861 attcatttta acacaaaaaa ggcttcagga caaatgagga agcagcagaa aagcaagtaa
    10921 aaagcctctt cctttaagga aaaagacttc ttatactaag agcaaactag gaagctagcc
    10981 gcaggcagct caaaacacgg ttttgaggtt gtagataagg cgacgttgac gtggtttgaa
    11041 gagattttca aagagtatta ttcttattgc caggcaccta agttgccaac gtagtaacta
    11101 tcaggtgtgt aggtattgcg aagcatctta cctgatgaag ccagataata ctacttgcca
    11161 ttgtctttga cccaatcatt cgcaatcatg gaaccagaag aacttacata ataccattct
    11221 cccttgtcat aaacccaagt actgactttc atggttcctg agcaattaaa ggcaaaaaaa
    11281 ctgtccaata tcattcgttt tttaaaagca tttgacacta catcatctac gctgtagtac
    11341 atagatacat caaacgtaaa agccaaaata tcgaaaaata tacaactttt aaaggcagca
    11401 tttcattttt taaagtctaa caaccataga actgaaatca gagcaaggca tcaatttcct
    11461 actcttagta cgtctatttt gatggttgaa gtgaagattt ttttatttaa cgtagacaat
    11521 ttccaacttc ccaaaagcca catctccacg gatagtcaag gttttgctgg ttggggctac
    11581 aggagcgtca gccttagctg caccaaagga ggtttctact ttcaaatcta cacgccagtg
    11641 ttgtggaaca tagacggttg cattcccgaa ggccacttca atatttaaag ttgcaaaatc
    11701 acctagcatc tctgcattat catagtagat tttagcatcc ccaaaagcga cttccacttg
    11761 gtcatctacg agatcttgat cttgcttata gaaggtcccg ctaccaaaag cgacttcctt
    11821 atccgtgacg actgtttttt tcccattgta ccaccatttt ttttcattcc agaacttact
    11881 tgaatgcgtc agataaccaa caccaagtac caccaagatg ctagcccaaa taagagaatg
    11941 attggtaact ggtaacaagt cataagcgta atttgcaatg atgagcgcca gtaaacctgt
    12001 aaaaactgcc gaagtgagat gacgtctaag gatggactca atggacttat aagcaaaaaa
    12061 aacaatacct agtaaaggcc atattttacc atccaaagaa ggaattccaa aattcccttg
    12121 cagcaagatc caagctgcta aaaccaacaa aacaatacca aatgctttct ttttcatgtt
    12181 ttttacctca tgtttcttag attttctttt aggagggatt ggtaatgccg tgagacatga
    12241 acctccttgt gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact
    12301 gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc
    12361 aagatagact ccaactcata gagcttgagg cgaacctcat aagcttcctt ctggttatga
    12421 gcgtagatct tgctcccttc tgtttcaaag aagagaattt ctgacaggtc tagataatat
    12481 tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa gagccgttgc
    12541 aagtctgcaa tttcatctgt caaagtgggg gtcttgatga caatttcagt ctcctctaaa
    12601 ttgccgtcaa tctcaattcg taacttcatc acatctcctt tctgactcta ctatatcaaa
    12661 gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg
    12721 taggactagc ttaacttaca tgtaagaata ggaagaaaag gaatccccac accaaaccac
    12781 aagcatagcc aaccaagaca tccttgggat aatgaacacc ccctaaaacc ctcaccaacc
    12841 ccagcaaagc tgaaaagatc aagcatacta agccaatagg tagactagca tgcagacagg
    12901 ccatggagat gatagttgcc gaaaagacat ggcgactggg catcgaccgt cccgaactat
    12961 ccttatcaag aaggggacag atatcccaag tttcataagg tctcgggtga ttgattttct
    13021 tacgaaacag ggacaaggcc acaaaacctg atgcaggaat aagcacacaa accccaactt
    13081 gctgaccaag tcctagttgc aggtaagtgg tgactagcaa gatcagatag accaggggca
    13141 tggcgactgt catcaaacga ttgaaactgc gtaataggaa taaaagaatt ggacgactag
    13201 ttagtctgga gctgatattt cgataccatt cttgataatt tttcatttat gcttctcata
    13261 cttttctaga acttgttgag atgttttccc cttggcaagc caatccacta gcttgtccaa
    13321 gcgacgtatt tcctgcatca gaggatcatc aatttcctca atacggacac tgcaaatctt
    13381 ccctgtaatt gcaattcgtt cagggacata atatggtgct tgtctaaaaa aatctccgta
    13441 agtaacatcc ctatccagac aagcaagaac atcactcact tcataccctg tcaaccaact
    13501 ggtcacttgg tgaactgact ctgcctttcc accctttcgc tcaacttttg caatcaaggc
    13561 taagtagaca gcagcaaatt tcatattgta taatttctga ctcatacttc tctctttcta
    13621 tgtgtactag tataaataag aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct
    13681 gcttcatctt ctgtaaattg actattgtac aagtcagcgt agaagccacc ttgcgccatc
    13741 agttcctcat agttgccttg ctcgatgata tttccatctt tcatgaccaa gatcaagtct
    13801 gcatttcgga tggttgacaa gcggtgggca atgacaaagg atgtgcgtcc ttccatcaaa
    13861 cggtccatgg ctttttggat caattcctct gtccgtgtgt caacagaaga agtcgcctca
    13921 tccaaaatca aaagcggtgc atccttaaga agggcacgag caatagtcaa tagttgtttt
    13981 tgtcctacag acaaggtcac ggtgtcatcc aagatggtat catagccatc tggcaaggtc
    14041 ataataaagt ggtgaattcc cacagcctta ctagcttcca tcattcgttc atcactaatc
    14101 cctatttgat tatagatgag attgtctcga atagttcctt caaagagcca ggtatcctgc
    14161 aagaccattg aaaaggcatc atgcacttct gaacgcgtca tagccttggt atccacacca
    14221 tcaatgtgaa tacttccctt atcaatctca tagaatttca tcaaaagatt gacaatggtt
    14281 gtcttaccag tcccagtcgg cccaacaatg gcaacctttt gaccagcatg aactgtcgca
    14341 gagaagtcat agtcttgaac attgacaccg tccaccagaa tttctcctgc tgacacgtcg
    14401 tagaaacgtg gaatcagatt gaccagagtt gatttaccag aacctgttga cccaataaag
    14461 gccactgttt gaccagtttc tgctttaaag ctaacatgtt caataactgc ctccgaattt
    14521 gccgcatagc ggaaggtcac atccttaaac tcgacctgac ctttgaagtt ttcatcagtc
    14581 agctgcactt gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg attaatccgc
    14641 ttagcagaga ccatagtttg gggaagaacg atgaagagtg ctcccatgag aaggaagtcc
    14701 atgacaacct acatggcata agacatgaaa acaatcatgt cactaaagag aggcagacgc
    14761 gctatcggag cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc cacactcaaa
    14821 ccacttgaaa tccccatcat gataggattc aaaatagcca taagacggtt gacaaacaaa
    14881 tttaaacggg tcaattcatc atttactgct gcaaattttt cattttgata atcctctgca
    14941 ttgtaggcac gaacgacacg aatacctgtt aaactctcac gagtgatact gttcagttta
    15001 tctgtcagcc cctgaatcaa ggactgtttt ggaaaggcta gcgtcatcaa aacggtcgtc
    15061 atcaggacgt tgacaatcac tgccacaagt acggcccaga gccagtattc tgaatgacct
    15121 aaaatcttcc caatagccca gatagccata attggaccac acgttaccac ttgcaagtcc
    15181 atagtaatca acatttgaac ttgagtaatg tcattggtag tacgcatcaa gaggctagga
    15241 attgaaaatt tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa aatatcactt
    15301 ctcagcctac tagtataaga agccgccact cgggatgcaa aaaatccaac tgcaactacg
    15361 gacaagaagg caagaaaggg cattcccatc atcatgcttg ccggctgcca caactcatct
    15421 aaattagttc cttgactacc tagcaaatcc gtaattttcg agatataggt cggcacttcc
    15481 aactctagat agaccgaaaa gcaagtaaag agaatggcta gtaaaatcat cccccattct
    15541 tttctactaa ttcttttgac taatttcttt attctctcct cctattccct tgatatttgc
    15601 ctgtagttga ccgagaactt tctcaaaaat cagtaattca tcttcatcaa tgtcttccat
    15661 caactgcttg tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt
    15721 gtccgtcaga cgaacaaact tagcccgctt atcaacagga ctcgcctcca attccaccaa
    15781 accattttgc actatacgct taaccagatt actagcaaca gacttggtaa tattgagttc
    15841 ctgctcgata tctttaatca agaccaagtc ttggtttttc tcgcgattat ccaaaaaatg
    15901 cacaacctga ccttgcggcc cacccataaa ttcaatgccg caacgtttgg cttccttttg
    15961 caccatcagg tgaatttgat gaccaaaacg cttaaagact aacatcggtt tatccataat
    16021 ctcccccttc taaataaaaa tagttctctg gagaataatt aaatttctat gagaactatt
    16081 ttcttgatta aaaaaatccc aagtgatttt ctcacttagg atcatgttct ataggttaaa
    16141 ttaaaaccca tctacgttcg tataaatctt ttggacgtct tcgtcgtctt caagaacgct
    16201 gtaaagtttt tcaaaggttt caaggtcttc gcctgacaat tccacttctg actgaggaat
    16261 catttccaat tcagtcactt ggaattcttc aataccagac tcacggaggg caacgatagc
    16321 cttgtgaagg tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc
    16381 atccacatcc acatccgctt cgagcaattg ctcaaagact gcgtccgcat cttcacctcc
    16441 aaatacaata acacctttgt tgtcaaagag gtaagaaaca gaacctgaag cgcccatgtt
    16501 tccgccgttt ttaccaaagg ctgcacggac attggctgct gtacggttga cgttagaagt
    16561 caaagtatcc acaattagca tagagccatt tggcccaaaa ccttcgtaac gtccttctgt
    16621 aaaggtttcg tctgtgtttc ctttggcttt atcaatcgct ttatcgataa tgtgttttgg
    16681 cacttgggct tgtttagcac ggtcgataac gaatttcaaa gctgagtttg attctggatc
    16741 tggatcacct tttttagctg ctacatagat ttctacacca aattttgcat atactttaga
    16801 gttggctcca tctttagccg ttttcttggc tacgatattg gcccatttac gtcccattag
    16861 gaatctcctt ttttcacatt ttaatctttc ttattataac acaagttttt ttgattttca
    16921 ctagaggaaa tggattttat tagcaaatca agctaggata gcactttacc tgctaagatg
    16981 gtcttgcctt tctatcttta tcaacagaca ctcatccaca ttcaaaaaac aaactagacc
    17041 attatctgca aatagaaagt ttcagccaag tttgacaaag tcagctcaaa ttactgtttg
    17101 aagtttgtag atataagcga caaaaacaat catactgcac cttttgttga cagtctactc
    17161 cagacatatc atagttcaag taaatacttt gaaatccaac agttcttata ggcgctattg
    17221 tattctaaga aatcaataga agagtttcta agcaaacctc taatactcaa taaaaatcaa
    17281 agagcaaact agaaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgcggatag
    17341 ggctgacatg gtttgaagag attttcgaag agtataattt acgtgttcct aagatggaga
    17401 agttagacta gtacactggc acttctaaac cattgctagc aattgatttg ttcatattta
    17461 atttcatttt ttccataaat gggtattaga tataaacagc aaaatatttc cgatacgtgt
    17521 cattcttgaa tttccaatca tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa
    17581 ggaattggct acccttttta cttttttaca catcctgttt gatagactca ttttaacatc
    17641 acgagcatac tccaatggaa atcgctaggc aagagataaa ctttcagata ttcgcagaga
    17701 gctcatcgcc tctttttgtc gcaaacattc ttctctccta atcattttct accttatcct
    17761 ctacctgagg atagagagtt gttccccaaa tagaaatcgt ccgcttacgc actagtggca
    17821 aatcggtttt ttcataaacc gtacgccacc attcccaggc aagcccggta cactctctaa
    17881 ttttgacaga gagattgcga acattccctt ttaaaggaat actagtggta aagtgagccg
    17941 tcaaatcctg cccatttctg tcccaagcct taggagtcaa gacttccttg ccttgatgat
    18001 cataggataa ttcatcccaa gtaatataat attgagcaac ataggcacca ctatgatcca
    18061 gcagtaaatc tccgtttctg taagctgtaa ccttagtctc aacatagtct gtactgtttt
    18121 gaaaggtcgc aactacattg tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg
    18181 gatgatcggc tgtaaagcga ctgccttctt gaatcaagtc ctctaccata tccaccttgc
    18241 ctgttacaac tcgggcaccc gaacttgggt cgccccctaa aataaccgcc ttcacttctg
    18301 tattgtccaa aatctgcttc cactctgtct gaggagctac tccttttatc aaagattcaa
    18361 aagcagcctc tacttcatca ctcttactcg tggtttccaa cttgagatag acttggcgcc
    18421 cataagcaac actcgaaata tagaccaaag gacgctctgc agaaattcct ctctgcctta
    18481 aatcctctac cgttacagta tcttgaaaca catctcctgg atttttaaca gcatctacgc
    18541 tgactgtata ataaatctgc ttaaaattaa caatctgaat ctgcttttcg cctgaatgga
    18601 cagagttaaa atcaatatca agagaattcc ctatcttttc aaagtcagaa ccaaacttga
    18661 ccttgagttg ttccatgctg tgagccgtga ttttttcatg ctgcattcta gctgggacat
    18721 tattgacctg accataatct tgatgccact tagccaacaa atcgtttacc gctccgcgaa
    18781 cacttgaatt gctggggtct tccacttgga gaaagctatc gctacttgcc aaaccaggca
    18841 aatcaatact ataagtcatc ggagcacgat cgaccgcaag aagagtggga ttattctcta
    18901 acaaggtctc atccactacg agaagtgctc caggatagag gcgactgtcg ttggtagctg
    18961 ttacagaaat atcacttgta tttgtcgaca agctccgctt ctttctttcg ataacaacaa
    19021 actcatcggg tagctgatta ccctctttga tgaaacgatt ttcaatactt tctccctgat
    19081 gggtcaagag tttcttttta tcgtaattca tagctagtat aaagtcattt actgctttat
    19141 ttgccatctt ctacctccta ataagttcct ggattgagtt gcataaactc agacttgttc
    19201 agcgaaatca gccgtggttg gactaagtaa tccaaaattt cctcgtacaa ttcttctgag
    19261 acattgcgtc gccgtctggc taaataagaa gtcggaatga ccgtattatc caacataaat
    19321 accttatcta agtcaatcaa ggttggtctt gtaaaaggat tacgagctag atccggctct
    19381 tctatcataa agttcttgac caaacgtctg gtcaagagag ctggtttgaa ggtctgattt
    19441 ttaaccaact ctttgttttt agtcatgctg ttgtcaatac agatatacat atgattcttc
    19501 acagccaaat cgctactaat agtcggaaaa ggcaaataaa gagctacaac atctcctctc
    19561 ttaatcaagc aagagcaccc ccttttctcc taatgtaaca tagacaggat tgaccaagtc
    19621 ttctgattga ctcagaattt ccaaagtttg agtttggcgc gctgtcaatt tagtagcatc
    19681 ttgtctcttc aatacaaaat gcttgtcgcc aataaccttg acaatataat ccttctccaa
    19741 agctgactgg taaatccaca tcagatgttg tctgtcctga gaactcaaga gagaaggatt
    19801 ttcaagcctc ccgatagtct gataaaaatc aaaaacagga gctaactcct gccaatctga
    19861 ttggctagtt gtcaaggcta gaaaaagggc tttgcgagct gatacttctt ggttagcctt
    19921 gagagttact ttcccctcca agttttttag aaatcgggaa actccagaaa gcaaattttt
    19981 ctctaactgc gagaaataaa aacctttcgt tcccagacat aagtctttca tgtcgctttc
    20041 tctagcaaat aagagctcaa acatttgata gtaaaagaaa aatatctggc actgggtcgc
    20101 gctcatcttt tccttatcgg cttctttttt taaccagagc aagggcgaca ggtagctgga
    20161 ttgagacatt tcctctacct cctactcttt tttaactgga gcatctgcac tagctgccac
    20221 ttcttttgac tggatacttt cccactggtt aatctcctct gagataagac cttcgcatgt
    20281 cttgacaaat agggcaaaag ccttggtctt tcctgcatat ttctccgttt ggcattgata
    20341 gaggaatttt tctttctcca ggagttgcgc agttttttgg taagaaatcc aattttcctt
    20401 tgcattatac aaattgataa tcccctcaca cagcaagccg agactggata aggcaaccga
    20461 aatcaaacgg tagcgatcac ctggcatagg aatagcacaa aagacagcta tgaggaaacc
    20521 tgccacgatt tctgttattt ttaatacctt atagcgccta cgatgttgaa cgcttttctt
    20581 taaaaaatga gctatctgta cgtctaatcg ctctgtcagg tacatttctt ctggcgtcat
    20641 attcgtaact cctttcattt actttgataa ccatagtata acatatttga atatcaaagt
    20701 atagtaaaaa ctggactata acttattaga ctccctgcga aacaaaatat ggtatagtag
    20761 ttctatgaat tatgaagcaa gtaaacaatt aactgat
//
LOCUS       DBEJZJ010000035        19870 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000035 DBEJZJ010000000
VERSION     DBEJZJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.35"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL3R8_001618"
     CDS             complement(112..387)
                     /locus_tag="ACL3R8_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR1314470.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(493..1332)
                     /locus_tag="ACL3R8_001619"
     CDS             complement(493..1332)
                     /locus_tag="ACL3R8_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR1314471.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1474..2322
                     /locus_tag="ACL3R8_001620"
     CDS             1474..2322
                     /locus_tag="ACL3R8_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR1314472.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2415..3332)
                     /locus_tag="ACL3R8_001621"
     CDS             complement(2415..3332)
                     /locus_tag="ACL3R8_001621"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR1314473.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWY"
     gene            3809..3958
                     /locus_tag="ACL3R8_001622"
                     /pseudo
     CDS             3809..3958
                     /locus_tag="ACL3R8_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="ACL3R8_001623"
     CDS             complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="ACL3R8_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR1314474.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4594..4938)
                     /locus_tag="ACL3R8_001624"
     CDS             complement(4594..4938)
                     /locus_tag="ACL3R8_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR1314475.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="ACL3R8_001625"
     CDS             complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="ACL3R8_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR1314476.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5305..5392)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5487..6086)
                     /locus_tag="ACL3R8_001626"
     CDS             complement(5487..6086)
                     /locus_tag="ACL3R8_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR1314477.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6799
                     /locus_tag="ACL3R8_001627"
     CDS             6557..6799
                     /locus_tag="ACL3R8_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR1314478.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALE"
     gene            7076..8089
                     /locus_tag="ACL3R8_001628"
                     /pseudo
     CDS             7076..8089
                     /locus_tag="ACL3R8_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8405..9379)
                     /gene="pta"
                     /locus_tag="ACL3R8_001629"
     CDS             complement(8405..9379)
                     /gene="pta"
                     /locus_tag="ACL3R8_001629"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR1314479.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9423..10319)
                     /locus_tag="ACL3R8_001630"
     CDS             complement(9423..10319)
                     /locus_tag="ACL3R8_001630"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1314480.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10316..11134)
                     /locus_tag="ACL3R8_001631"
     CDS             complement(10316..11134)
                     /locus_tag="ACL3R8_001631"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR1314481.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11118..11789)
                     /locus_tag="ACL3R8_001632"
     CDS             complement(11118..11789)
                     /locus_tag="ACL3R8_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR1314482.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11917..12486
                     /locus_tag="ACL3R8_001633"
     CDS             11917..12486
                     /locus_tag="ACL3R8_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR1314483.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12599..13558
                     /locus_tag="ACL3R8_001634"
     CDS             12599..13558
                     /locus_tag="ACL3R8_001634"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR1314484.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13568..14683
                     /locus_tag="ACL3R8_001635"
     CDS             13568..14683
                     /locus_tag="ACL3R8_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR1314485.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMH
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14688..15035
                     /locus_tag="ACL3R8_001636"
     CDS             14688..15035
                     /locus_tag="ACL3R8_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR1314486.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15043..15258
                     /locus_tag="ACL3R8_001637"
     CDS             15043..15258
                     /locus_tag="ACL3R8_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR1314487.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15341..15982
                     /locus_tag="ACL3R8_001638"
     CDS             15341..15982
                     /locus_tag="ACL3R8_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR1314488.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16000..16689
                     /locus_tag="ACL3R8_001639"
     CDS             16000..16689
                     /locus_tag="ACL3R8_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR1314489.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGKPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16686..17366)
                     /gene="radC"
                     /locus_tag="ACL3R8_001640"
     CDS             complement(16686..17366)
                     /gene="radC"
                     /locus_tag="ACL3R8_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR1314490.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHLSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17409..19700)
                     /gene="pcrA"
                     /locus_tag="ACL3R8_001641"
     CDS             complement(17409..19700)
                     /gene="pcrA"
                     /locus_tag="ACL3R8_001641"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR1314491.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSVLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         6146 a         4182 c         3581 g         5961 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaattgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg
      541 agtttgaata atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa
      601 gctttctttc atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc
      661 tacagcacgt tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt
      721 tccacgacct ttaaccattg gctgcaattc atggtctttc atttgcatga caacacggat
      781 attgagaagg gagctcaaca agccagttac acggccaatt cgtccacctt tgacaagatt
      841 ttccaaagtt gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacatgaga
      901 taaaattgcc tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa
      961 tttcagggct tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct
     1021 agcaccttgg cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag
     1081 aatctggcca ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg
     1141 ctgacttgtt ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc
     1201 tttcaaatcc gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt
     1261 aatatctaat tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt
     1321 aatttttgtc atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta
     1381 attatatcaa aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt
     1441 gatataatca acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt
     1501 accattttac taggtgctgc tatttatgct tttggactga cttattttgt agttccccat
     1561 catctctttg aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc
     1621 cctgtttccc tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatc
     1681 tttggagcca aatccctcta ttctagttta ctaggaacct tagctttgtc cgcctggtta
     1741 gctttttttg agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc
     1801 cttatagcgg gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca
     1861 actggcggaa ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga
     1921 aaactgctct ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat
     1981 ttgagattgg tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg
     2041 attggtgaag gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa
     2101 cttgctaagg cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc
     2161 tactatagta aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg
     2221 aaaacgaagg aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc
     2281 catgaaatcc taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga
     2341 cctcaaaagt tagactaaat catctatctt ttgggttaca gacaacctct tttttatttt
     2401 atttactcaa gctcttaata ccaattccga gttacttctt catcagcctt taactgatcc
     2461 actaattggt caactgagtc aaatttggtc atatctcgaa tgcgatcaag ccaataaacc
     2521 atgacggttt ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct
     2581 tcttctccat caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctc
     2641 tgaatctcaa catcaacaac ataaacgcca tctgctggca tataagtacg gtctaaaagc
     2701 actaaattcg ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata
     2761 cctcttgatg gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa
     2821 atagcttgac ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca
     2881 atgataactt ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca
     2941 aatgtataat caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca
     3001 aagaattctt gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct
     3061 tctacacctt cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac
     3121 aaatctggat gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg
     3181 ataggcaaca aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc
     3241 ttatgtatgc catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct
     3301 ttttggtttt ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat
     3361 ttctggaaca gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa
     3421 agcactttat tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt
     3481 aggacatctt caaaattttg caaggagtga ttagacttgt tcggtaacca taaagtgtca
     3541 tactatgctt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaaa aagccaaagc agtaaagaaa aactagatga ctgctttcca
     3781 acaacttcca tctagtgtgc ttcagactgg gctatttttc tctccatctg ttagcttgga
     3841 ttctcagacc gtttcagcta aagaatatct tttcccttat cagaaggaac gggctcaaac
     3901 cactcagaca agtgaaggga cgacaagcca atatttgaaa ccagatagca gtttttatag
     3961 tcaattgaaa taaaatctga agaaatcgag taggaaactc atatcaattt ttaacagtgt
     4021 tctattccag attcatactc aatgaaaatt aaagtgcaaa ctaggaagtt agccgcaggc
     4081 tgtacttgag tacggcaagg tgaaactgac gtggtttgaa tttgattttc gaagagtatc
     4141 aatccactat acatattaaa aagtatgggt atcaaaacaa aaaaacaggc tctccgaaaa
     4201 ctcggaaagc cttattttaa gctgtttcta gcttcctcac ctttacattt caaggttcgg
     4261 gataaaaggt tcaatggacc tttttattta gcgattgggt aaacagaaac ttgtttttta
     4321 tcgcgtcctt tacgttcaaa gcgtactacg ccttcaactt tagcgaacaa agtatcgtct
     4381 ccaccacgac caacgtttac acctggatag atgtgtgtac cacgttgacg gtaaaggatt
     4441 gatccacctg ttacagtttg tccgtcagct gctttagctc caagacgttt cgcttgtgaa
     4501 tcacgtccgt ttgatgtaga acctccacct tttttgtggg cgaaaagttg caagttgtta
     4561 agagtcattt ttaacataat gttttcctcc gtgttagttt tctgtgataa ctctggtttg
     4621 gacgaactca gaagagttct ccgataagtt tgccatacct aagaaaaatg attcaaagaa
     4681 taactgggtc atttctctct ggtgtgaagg aagatctttt ggtatttcaa ccatcagata
     4741 gccaccttca tcttcgttta attctaggat tggttcatag cctgcaaatt tctcaataga
     4801 attgataaag ttaatggcaa gcgtagaaac cgatgcacac acgacatcta agccgtattc
     4861 gccactctcg gcgtgtccag taatttccgc actcctcagc tcgccatctt cggctctctc
     4921 aaagactgct tgtatcatgt gttctcctta aaattaagcg ttaattgcgt tgatgacaac
     4981 ttttgtatat ggttgacggt gaccttgttt acggtggcta ccttttttag gtttgtactt
     5041 gtaagtaaca actttctttt gttttccttg tttttcaaca gttccaacta cagtagctcc
     5101 agcaacaagt ggagttccga caacagtgtt ttcaccacca acaagaacaa cttcgttaaa
     5161 agtaacttct tgaccagctt caacgttcaa tttttcaatg taaactgctt gaccaacttc
     5221 aactttaact tgttttccgc cagttttgat aattgcgtat gtgctcatta tgcacctcct
     5281 atgattttta tgggtttccc cgattttttt gtgaagactc gcctagcatc gtgggacaaa
     5341 ccacttaaac ttgaataatc aagcaacgat gttcgtgcgg ttgcacagga tcgtgcatag
     5401 tcaactcttc aagtgtagca tatttcctat tttcttacaa gtaataacac ctaaaatcaa
     5461 gctttttctt ttactttttt ctgccactag gcaaaaagca tactgagata aaaaatgctc
     5521 atcataatag gaacaccaag aatggtcttt tcatgataga aaatcgtcaa atagactgaa
     5581 aagacaacgc caaggacaaa actactaagc aggctaacaa atatgaaccc ttcacgcaaa
     5641 aaaggagtgt gcttagttcg gaaataatct ccaaaagcta gcattgttcg tttgatattc
     5701 cctgtcataa aggcattatt gtaggcaata cccgaaacct caccaaaagc agttgtcacc
     5761 agtcccatac agaaggccaa gggcggcact agatagatat tatctacagt ttgtggcaca
     5821 aaaccaataa ttattgatag gattgctaaa ggaatcaagg acagaataga ttttttcaca
     5881 attctcaatt tttccttata aatcgttaat aaaaagactc ccatcataaa cgctattaag
     5941 gttaaaagct tatccctaat atccgaaaca ttattttgta tgagctctac cgaaagaaag
     6001 acaacatttc cagcttgtcc agctacaagg gtattcccgc gaacaataaa agtgtaagca
     6061 tccacatatc cagcacaaaa cgtcaaaaaa gtgctaacct tttagactga cgtgatattt
     6121 ttcttatagg taataacctc attttccctc ccattgtatt ttctcttaga aatattgtac
     6181 cattttcttt ctaaaaaatc gtaggctacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acttggactt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcaa ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aagaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaataaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatgctt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc ccctatggat attacggagc ctatttttgt gtagaaaaaa
     7021 agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga
     7081 acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc agattttaga
     7141 catcatcaat aaggatacac acaaggaaat catcgccaaa ctggactatg aagctccatc
     7201 ttgtcctgag tgcggaaacc aattgaagaa atatgacttt caaaaacctt ctaaaattcc
     7261 ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc atttcaagtg
     7321 ctatcactgt tctaaaatga tggtcgctga gacttctatc gtcaagaaga atcatcaaat
     7381 tccttgtatc atcaaccaaa agattgatca gaagctaatt gaaaagactt ctatgaccga
     7441 cattgatcat cagttgtcta tttcaacttc aactgtcatt cgcaagatca atgattttca
     7501 ctttgagcat gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtctg
     7561 gggagtgact gtttcaatcg ggagatagag atgagcttta ttgctcagga ctttgataag
     7621 ctcaatatca taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat
     7681 acaaggctat caagcgatac tgaaagctca ttcaacaaga tagtcagaaa ctgagtgata
     7741 aacgatttta tcgccctact tttcgtatgc acttgactaa taaagaaatt ctagataaac
     7801 ttttgagcta ttccgaagac ttgaaacacc actataatct ctatcagctc ttgcttttcc
     7861 acctcttttt cagactctgt ttaaaacctt cctcaaagat aaagagaaaa tcgtcaacgc
     7921 ccttcaatta ccttattcca acgccaaact ggaagccacc aataatctca tcaaacttat
     7981 caagcacaat gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga tttttatcgc
     8041 tctgaacatc aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc ttttcttcaa
     8101 cccactacag ttgacaaaga gccagaaaac gcataatagc aggtgtcaag acacttaata
     8161 ttatgcgttt tctcatgaaa aaattctctt ttcatactca tttaaaatca aaaagggaat
     8221 ttatcgtttt acggacatgt atattacaga tttctatagg tcgtgtatag acaggatatc
     8281 atcgcttgga agttttcctt tttgacacca atcagtaatt tagttctcag gaattaatgg
     8341 cagtgctttt cgtacatagt ttcataacta cagtatagca tagtatatcg ctttatagtt
     8401 ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa acatcatctg
     8461 cattacatcc acgagaaaga tcattaactg gcttgtttaa accttgcaaa acaggtccta
     8521 cagccgcaaa gccacccagg cgttcagcca tcttgtaacc gatatttcct gcctcgatac
     8581 ctgggaagat gaagacattt gcttgaccag ctaccgtact tccaggagct ttcagagctg
     8641 cagtttcagg aacaaaggct gcatcaaatt gcaactcacc atcgatttca aggtcaggac
     8701 gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca ccaaaccctg
     8761 aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac atcttagctg
     8821 tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg atgttaatgg
     8881 cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct cctgaagtac
     8941 gagttacatt tggacgagtt ttgatgattt gtagagctgg acgaactgtt gaagctgttg
     9001 agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac atcacaccaa
     9061 agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt ttgcccttgc
     9121 gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga gggtcgatga
     9181 cctcataacc atccatgatt ccttcaattt caagataaat tttaattttt tcaggatttc
     9241 caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct tgaagaatac
     9301 gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg ttggctttga
     9361 gactttcaaa aacttccatg agttttctcc tttaagataa taattatact ctgagacagt
     9421 ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc cggcaaggga
     9481 ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta atggcaatgc
     9541 agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc tcccagcaaa
     9601 ggaaaaccga tataagaaaa atggactcgg atttgatggg ttcgaccagt gtgcaggtga
     9661 atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt atgggcatac
     9721 tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc aatcggagca
     9781 ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa gtagcgtttc
     9841 tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc gtgcttggca
     9901 aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac ctgctgattt
     9961 tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtatt agagtgattg
    10021 acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg gtcatcctca
    10081 tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc ctcagcggga
    10141 atgtaaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg cggttgatta
    10201 ttgaccagaa tcgctccacc tcgaaactta atcttagcca gcaatccctt agaaacctcg
    10261 tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc aaacctcatt
    10321 catccacctc accgataaag gcatccttaa cacggttcca gaaactggta tggctaggag
    10381 tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca atattacgga
    10441 aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt ggaataagtt
    10501 caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgataa acacgattat
    10561 taaggctggc aatttccgtt aattgcaaag cttcaatggt agggtgtaaa acagcaccgc
    10621 caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc ccgtctccac
    10681 gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt cgatcagacc
    10741 tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt tcaagaaaga
    10801 ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc aaattagtca
    10861 ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt ccagtatgaa
    10921 gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc gacaagagca
    10981 taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt ataaactgat
    11041 ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt tttctattgg
    11101 ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt tcctacaccg
    11161 tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat atcatcacga
    11221 atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc cagtcgcttc
    11281 ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc tatcgttgcc
    11341 cagaaattca tggccaaagt acgaatttga atttctgcca aaatagtctt agctccattg
    11401 atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga tgcttttcta
    11461 tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg caaaatatcc
    11521 actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc aatatcctgc
    11581 aaatcgtgtt ccaaggtcgc ataagtaatg ctacgacgag ccattttttc tttgatgctc
    11641 tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt ttgcttacga
    11701 tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg aatgtaagga
    11761 tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata ttatccgtca
    11821 aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct tattatacca
    11881 taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga aattgaattg
    11941 aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagttcac aggtgtcact
    12001 cctgttcttc aaacaaatta ctacatcgac acgcttgatt ttgaactgcg agaaaagaaa
    12061 gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa agtcccgcag
    12121 agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga gaactatctg
    12181 agtaaggaag aacttcctca agggctagta ctggatgaat tggcgaaaca tggtatccaa
    12241 agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat gaaaacagct
    12301 attggtctca tggcactgga tcagagccga tactttgata tgacagatta cgaattggag
    12361 cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt agagaaaaat
    12421 cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag tatgaaaaat
    12481 agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac aaatcccagt
    12541 tcatatatgt aaggtaaata taactaggat ttataaagtt tacagaggac ggtctataat
    12601 gtcagataga aaaaacatga aacttttcgc actcaactct aaccaagaga ttgcacaaaa
    12661 aattgcccaa gctgttggtg tcccacttgg aaaactatca tcacgtcaat tttcagacgg
    12721 agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat gatgtttaca tcatccaatc
    12781 aacaagtttc cctgtcaaca accacctaat ggaattgtta atcatggtcg atgcttgtgt
    12841 gcgtgcaagt gcccacagta tcaacgttgt ccttccatat tttggctatg cacgtcaaga
    12901 ccgcattgct tgtcctcgtg agccacttac agcaaaacta gttgccaata tgctggttaa
    12961 ggctggagtt gatcgtatcc tgactcttga tttgcatgcc gttcaggttc aaggtttctt
    13021 tgatattcca gtggataatc ttttcactgt tcccctattc gcaaaacatt actgcgataa
    13081 aggattgctt ggttcagatg ttgttgtcgt tagccctaaa aattcaggtg tcaaacgtgc
    13141 gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt atcgactacc ctcaagacga
    13201 tgcaactcgt aacgaaggtt atattattgg tgatgttgaa ggtaagaaag ctatcttgat
    13261 tgatgatatt ttaaatacag gacgtacctt ctctgaagct tctaaaatcg ttgaacgtga
    13321 aggagctaca gaaatttatg ctgtttctag ccacggtctc ttcgtcgagg gagctgctga
    13381 gcttcttgac aatactaata ttaaagaaat tcttgtgact gattcagtag caacaaaaga
    13441 aaaaactcct aaaaatgtat gctacatcac tgctagtgag ttaattggtg atgctatcgt
    13501 ccgtattcac gaaagaaaac cagtcagccc actctttgcc tacaataaaa agaaataagg
    13561 tgattctttg atttatttgg acaatgctgc aacgactcct atgtcagcag ttgctatttc
    13621 agctatgacc aaggttatgc aagaaaccca cggaaatcct tctagtattc atggtcatgg
    13681 tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa ctagcccagt tactaaggac
    13741 aaaacctcaa catatctttt tcacttctgg tgggactgaa ggcaataata ctaccatcat
    13801 tggctactgt cttcgtcacc aagaacaagg aaaacatatc atcacaactg ccatcgagca
    13861 ccatgctgtc cttgaaacaa ttgattactt ggttcaacac tttgggtttg aagcaaccat
    13921 tatccagcca gaaaatcaag aaatcacagc ccagcaaatt caaaaggctt tacgtgacga
    13981 tacgattttg gtttctacta tgtttgccaa taatgagaca ggaaacctac ttcccatcgc
    14041 tgaaattggc caaatactca agcaacaccc tgctgcctat catgttgatg cagttcaggc
    14101 tattggtaaa atcccaattc attcagaaga attgggcatt gattttctca ctgcttctgc
    14161 ccacaaattc catggtccta agggaatcgg ttttctctac gcatctagca tggactttga
    14221 ttcctatcta catggcggag atcaggaaca gaaaaaacgt gcaggaactg aaaatctgcc
    14281 tgccatcgta ggcatggttg cagccctaaa agaagaccta gaaaaacaag aagaacattt
    14341 tcaacatgta caaaatctag aaactgcctt tctggcagag ctggagggca ttcagtatta
    14401 cttgaataga ggaaaacatc atctccctta tgttctcaat attggatttc ctggtcagaa
    14461 aaatgacctc ttactccttc ggctagattt agctggaatt tcaatctcta ctggctcagc
    14521 ctgtactgca ggcgttgtcc aatccagcca tgttcttaaa gccatgcatg gcgcaaattc
    14581 agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca caaaataccg ttgaagacct
    14641 acaaaccctc gcaaaaacct taaaagaaat tatcggaggt tagccatatg gcatttgaaa
    14701 aaatcattca gttaaaaaat tgtcgttacg attacactct tagcccttct gttaaaaaat
    14761 tcaccctcaa agataacacc ttttttgaaa ctaaggttgg taactatgaa ctgactcgcc
    14821 ttttggaaaa agtgccaaac agcggtgaag gcttccaact caaaatcatc attaacaagg
    14881 aacttacagg ggctaaaatc aatatcactg acaagtttgg ccttcgtcta gttgatattt
    14941 tcaaatcaga agaccaccat attcatcagg aaaaattcta cttcctcatg gatagcttgg
    15001 tagaacgtgg tgtctttaca aaatcggaaa gatagagcca aaatgtttga actgacctat
    15061 aaggactgct atcatgtaga gcgtactctc aagtatgagg atcatgaggc tctcatgttg
    15121 actttgtcag gatgtgtaac cttaccagat acactttatg tgacttctct gacttttagg
    15181 ggcaaaaaag tttatcaggg gctggtcgga gacctctacc gttttctatc tcatgcagat
    15241 tttttacatc aaaactaaga tttttcttag ttttttctta tttttgttga ttttttcaca
    15301 atgtttctat aaaatagaag aatagaaagg ttgtgatttt gtgaaagata aacagtttgc
    15361 tattccaaaa gctacagcaa aaagactctc tctctactat cgaattttta agagatttca
    15421 tgcagaaaag attgaacgtg ccaactctaa gcaaattgca gaggctatcg gtattgattc
    15481 agcgaccgta cgtcgtgatt tttcctattt tggtgaactt ggtcgtcgtg gttttggcta
    15541 tgatgtcaaa aaattaatga cattttttgc cgatttgctc aatgacaact ctattaccaa
    15601 tgtcatgctg gttggtattg gaaatatggg ccatgccctt ctccactacc gcttccacga
    15661 acgtaacaag atgaagatta tcatggcctt tgacctagac gaccatcctg aagtcggtac
    15721 ccaaactcct gacgggattc ccatttacgg gatttctcag atcaaggata aaatcaagga
    15781 tgctgatgtg aagactgcta tcctaactgt tcccagcgtc aagtcacaag aggttgctaa
    15841 tctcttggtt gatgctggtg tgaaaggaat tctcagtttt tcaccagtcc atctgcattt
    15901 accaaaagac gtggtcgttc agtatgtcga tttgacaagt gaactccaaa ccctcctcta
    15961 cttcatgcga aaagaggatt agaaagcgaa aatcatttta tgaaaaaacc agttattggg
    16021 attacaggaa acgaaaaaac tcatccagat gatgacatca tgatgagcta cgcagcaaaa
    16081 ggctttgttg aaggcgttaa agatgctgga gggattccta tcatcctacc gattggtgat
    16141 caagaaatgg cctgccacta tatcagtttg attgacaagc tcatcttgac aggtgggcaa
    16201 aatgtcgatc caaaattcta tggcaaaccc aaaaccattg atagcgatga ttatcacctt
    16261 caaagagata tcttcgaact ggccctcatc aaggaagcta ttaaacagaa aaagcccatt
    16321 ttctctgtct gccgtggtac ccaactcttt aacgttgcca tgggtggaac tttgtaccaa
    16381 gatatcgaag accattggca ggattcttct gttgagtaca caactcaacg cttggtaaca
    16441 gaaccagata ccgttctcca agaaatctat ggagaaatct ctcatatcaa ctccttccac
    16501 caccagagca tcaaggactt agcaccaaat ttaaaagttg tggctcatga tcctaaagat
    16561 ggtatcattg aggctgtcat gagtacggat gatgtcgcct ttctcggtgt ccaatggcat
    16621 ccagaacttc tttttgaaaa tcgtcccaaa gataagaaac tctttgacta tgtcgttaat
    16681 gaactttaga ttaaatctgt cttttcacga taactaaagt aattagaatg agagacaatc
    16741 aaatggtcca agagaacaat ccccatcagt tcgcaggctt ctttaacaag tttagtgaca
    16801 tgatcatcat tttggctagg cgctaccgct cctgaaagat gattgtggac caagataaga
    16861 gaagtcgcca tatgcttgat tgcatagtgc agaatctctc gcggttcagc gatactacga
    16921 gttacagaac cgataaaaat ggtctgctga tggatgattt gattttgagt attgagatag
    16981 agtgccacca ggtgctcttg ttttttatcc cctaattcct gctgcatctt cttggccaac
    17041 ttttgactgc tgagaatact ttccatttca agagtctcgt gtttgtgaat acgatgcccc
    17101 agttcaatca tagcttgtaa ttctatggcc ttaacacgcc caataccaga caaactctgc
    17161 aattcctgca gggtcatttt tttcaaatcc gttaggcttg aaagattgtt caagactttt
    17221 tgggcaattt caaaaacgct agcttgacgt gttcctgtcc tgagtaaaat agctagcaac
    17281 tcttggttac taagcgcttc aactccttcc ttggccagcc tttctcttgg taatagtgaa
    17341 tcttcttgga atgaaatact gtacataaaa atcctcctca ctttattatt cgtgagaagg
    17401 atggaaaatt agattttttt ctcaattgga gccacactgg ctaaaagttt tttcaaacct
    17461 acttctggga aattgatttt caattcctgc ctagcaccgc tacctgaaac ttccagaaca
    17521 gttccctctc cccatttctt gtggagagca atgtcaccaa tggaccaatt tgcctcgcta
    17581 gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa gaacgcttga ctggattgat
    17641 tttggggcag caccgcgttt acggtcttga agagcctgag ccaaactcat accttgacca
    17701 aaggaaatac taccactgct atatgatgcc ttaaagcttg tatttgcagg acgagccaga
    17761 ccttgatact caagcaagtc tgaactgatt tcgttaataa aacgagtcgg acggttataa
    17821 ttggtacgac caaaaagcaa gcgtgagttg gcattggtca gatagagaat tttctctgca
    17881 cgcgtgatac ctacataggc tagacggcgc tcttcttcta attcatctgg atcttcagtc
    17941 gcacgactaa gtggaaagac attttcttcc atcccaatca aaaagacaac tggaaattcg
    18001 agacctttgg cagcatgcag ggtcatcaag gtcacttctg atgtctcctg actacctgaa
    18061 tctgtgtcgg caatcaaagc caagtcattt aagaaacgac tcagtttgtc cagaccagtt
    18121 tcctcttctg tcacatcagt ggtgtcatca aagttcttcg taacagaaag aaactcttcg
    18181 atattttcaa cccgtgcctt gctttctaga gtcgcttggg cgttaagaat atcgacataa
    18241 cctgtttttt ctaggacgga ctcaaccaac tctgtaatgc ttaagtggtc tagctgctcc
    18301 cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt gggctgcctt acccttgata
    18361 ccagacaaca taatattagc agaagcatcc agcatagaca tattttgcaa atttgcaaaa
    18421 tcacggattt tctcaactgt acctagacca attccacgtt taggctcgtt gataatacgc
    18481 tcaaaactaa tattgtcact caaattagca ataaggttga gataagcaat aatatcgcga
    18541 atttccttac ggctgtagaa tttggttccg ccaaccatgg tataaggaat gttagacttg
    18601 agcagggctt cctcaattgt acgggactga gcattagtcc gatagagaac tgcaaaatcc
    18661 ttatgaagga agttttgact gcgactaagt tcatcgatgg ttctggctac aaatacagcc
    18721 tcatccagct catcatcggc acgatagtaa acgatttgct ccccatcagc gttttgagtc
    18781 cagagatttt taggacggcg atttttatta tttttaataa cctcgttggc cgcttggaga
    18841 atggttttgg ttgagcggta attttcctcc aacaaaacaa ccttggcttt ggggtaatcc
    18901 ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc aaccgtagat agactggtcc
    18961 gcatccccaa ccacacagat atttttaaaa cgggaagcca agagtttgac taattggtac
    19021 tgagcgtggt tggtatcttg gtactcatca acgtggatgt attggaattt ttgctggtag
    19081 taggtcaaaa catcaggatt ttgatcaaag agacgcaagg tcagcataat caaatcatca
    19141 aagtcaacgg attcagactg acgaagttct ttttgatagg ctgtataaca ctgggccaca
    19201 atttgcgtat acatatcgcc agcttgggca gcataagcaa catcatcaat caaatcattc
    19261 ttagcattgg aaatggtccc caaaatagtt cgttcattcc attttttagg atccaagttc
    19321 aactgtttga gaatacgttt catgagcgtt cgctgttcac caggatccac aattgtaaaa
    19381 ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa tacgcacaca catggagtgg
    19441 aaggtcgcaa tcagacagtc ctgagtcgct ggattgaggc tataagcacg ctctttcatc
    19501 tcacgcgcag ccttgttggt aaaggtaatg gccaagatat tccaaggatt gaccagcttt
    19561 tcatcaatca aataagcgat acggtgggtc aaaacacgag tctttccaga accagcccct
    19621 gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct cagcctgacg gtcattcatt
    19681 ccatttaata atgcgttcat cttctcttcc ttactcttga agtcaatatt tctattatat
    19741 cagaaatcag ggaaaataga aactttacgg ggagtagcaa aatatagtgg attgaaacta
    19801 gaatactaca ctgtgggttt ctaaaacact cgactttttc acccaatttt ttcataaact
    19861 agctcaatac
//
LOCUS       DBEJZJ010000036        19778 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000036 DBEJZJ010000000
VERSION     DBEJZJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.36"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..617)
                     /locus_tag="ACL3R8_001642"
                     /pseudo
     CDS             complement(1..617)
                     /locus_tag="ACL3R8_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(726..1244)
                     /locus_tag="ACL3R8_001643"
     CDS             complement(726..1244)
                     /locus_tag="ACL3R8_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR1314492.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1281..1409)
                     /locus_tag="ACL3R8_001644"
                     /pseudo
     CDS             complement(1281..1409)
                     /locus_tag="ACL3R8_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="ACL3R8_001645"
     CDS             complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="ACL3R8_001645"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR1314493.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="ACL3R8_001646"
     CDS             complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="ACL3R8_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR1314494.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2700..3590)
                     /locus_tag="ACL3R8_001647"
     CDS             complement(2700..3590)
                     /locus_tag="ACL3R8_001647"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR1314495.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3587..4225)
                     /gene="tmk"
                     /locus_tag="ACL3R8_001648"
     CDS             complement(3587..4225)
                     /gene="tmk"
                     /locus_tag="ACL3R8_001648"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR1314496.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4445..5242)
                     /gene="proC"
                     /locus_tag="ACL3R8_001649"
     CDS             complement(4445..5242)
                     /gene="proC"
                     /locus_tag="ACL3R8_001649"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR1314497.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5246..6508)
                     /locus_tag="ACL3R8_001650"
     CDS             complement(5246..6508)
                     /locus_tag="ACL3R8_001650"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR1314498.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADDDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6518..7627)
                     /gene="proB"
                     /locus_tag="ACL3R8_001651"
     CDS             complement(6518..7627)
                     /gene="proB"
                     /locus_tag="ACL3R8_001651"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR1314499.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7728..9623)
                     /gene="cbpE"
                     /locus_tag="ACL3R8_001652"
                     /gene_synonym="pce"
     CDS             complement(7728..9623)
                     /gene="cbpE"
                     /locus_tag="ACL3R8_001652"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR1314500.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREEIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQYINAASKDYDATVFDIRQDGLVNISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYVVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     HWFYLTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQY
                     MGQWYYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            complement(9626..10513)
                     /locus_tag="ACL3R8_001653"
     CDS             complement(9626..10513)
                     /locus_tag="ACL3R8_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1314501.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10503..10964)
                     /gene="lspA"
                     /locus_tag="ACL3R8_001654"
     CDS             complement(10503..10964)
                     /gene="lspA"
                     /locus_tag="ACL3R8_001654"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR1314502.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10961..11869)
                     /locus_tag="ACL3R8_001655"
     CDS             complement(10961..11869)
                     /locus_tag="ACL3R8_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR1314503.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLARKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11862..12059
                     /locus_tag="ACL3R8_001656"
     CDS             11862..12059
                     /locus_tag="ACL3R8_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR1314504.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12110..12781)
                     /locus_tag="ACL3R8_001657"
     CDS             complement(12110..12781)
                     /locus_tag="ACL3R8_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR1314505.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLFA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNIYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12835..13056)
                     /locus_tag="ACL3R8_001658"
     CDS             complement(12835..13056)
                     /locus_tag="ACL3R8_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR1314506.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWKMEPVLTLL
                     VHGFCPRDTDDLGYIGGGNHLCKGSAARF"
     gene            13328..14137
                     /locus_tag="ACL3R8_001659"
     CDS             13328..14137
                     /locus_tag="ACL3R8_001659"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR1314507.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14318..15193)
                     /gene="aguB"
                     /locus_tag="ACL3R8_001660"
     CDS             complement(14318..15193)
                     /gene="aguB"
                     /locus_tag="ACL3R8_001660"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR1314508.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15203..16288)
                     /gene="aguA"
                     /locus_tag="ACL3R8_001661"
     CDS             complement(15203..16288)
                     /gene="aguA"
                     /locus_tag="ACL3R8_001661"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR1314509.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16285..17412)
                     /gene="nspC"
                     /locus_tag="ACL3R8_001662"
     CDS             complement(16285..17412)
                     /gene="nspC"
                     /locus_tag="ACL3R8_001662"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR1314510.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17412..18671)
                     /locus_tag="ACL3R8_001663"
     CDS             complement(17412..18671)
                     /locus_tag="ACL3R8_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR1314511.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18668..19528)
                     /gene="speE"
                     /locus_tag="ACL3R8_001664"
     CDS             complement(18668..19528)
                     /gene="speE"
                     /locus_tag="ACL3R8_001664"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR1314512.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5744 a         4546 c         3521 g         5967 t
ORIGIN      
        1 taattctcaa gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa
       61 aacacatttt gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac
      121 ttactcttat tattctctat atagttagag tcaaggttct taacctcttg aagttcattt
      181 tctttacttc tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag
      241 tcattttctt ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta
      301 ccaagtccaa gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct
      361 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
      421 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
      481 tatttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
      541 ctatcaacta atatctccgg tacttttaag aagttaaatc ttttcgcttc tctgttataa
      601 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
      661 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
      721 ataatttata atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt
      781 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
      841 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
      901 gcagagatag aatgaatatt ttcatttaat tttgctttca actcttgcag agataaatga
      961 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     1021 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     1081 gtccaaccaa cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc
     1141 ttatctttta aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc
     1201 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     1261 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac
     1321 gctataactg ctgctccaac catcggtatt ccgtatgggc ttaataaaaa acttaatacc
     1381 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
     1441 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccagt cgtggtaggc
     1501 agcgtagagt tgactcttat tccactggta aatcttagcg acttccttaa tagcttgatt
     1561 tttcttcata ccttgctgga tacgagcttg gatttctaag aacaagtctt cctcgtcttt
     1621 ttcttccaca tcctgactgg caccttcaac aatcagaaga cattcaccct tgagagacgt
     1681 ttcagcaatg ctttccagca attcagaaat tgtacctctt tggtattctt catagatttt
     1741 ggtcaattcc ctgaccaaga caacggagcg gtcaccgtag acttctagca tattttccaa
     1801 tgtatctgcc acacgatggg gcgattcata aaaaatctga gtttcaggat agtctttttt
     1861 cgagtcgaaa aattgctttt gctggcctga ttttctcggt aaaaagccgt aaaagatatg
     1921 tggctgcggc gctaaaccac tggcaatcaa ggcggaaatt cctgcagagg cacctggaac
     1981 tgtaacaact gcaatttctt cctcaatagc tgccttaacc aaatcatgac cagggtctga
     2041 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
     2101 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
     2161 aatgtcaaaa tgcttgagca aaagacctgt attgcgcgta tcctcagcag caatccagtc
     2221 cacttctttc aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt
     2281 tgccactaga tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat
     2341 gcctactccc tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt
     2401 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatgcgacg gacactttca
     2461 cgaacatgct tggccttgac aggagcatct gcttccacct cacccaagcg ttctcgcaac
     2521 ttagaatttt ccaaacgaag agctgtattt tcctctacca ggctcttgag atttttcttg
     2581 atggcttcca catcggccaa ggttaccaat aactgttggg aaaaatcatc cagcgcgtca
     2641 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
     2701 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
     2761 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
     2821 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
     2881 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
     2941 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct
     3001 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
     3061 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
     3121 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
     3181 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
     3241 tccgcttgct cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
     3301 cccaccaatt cccgaatgcg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
     3361 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
     3421 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgctat ttccaagctt
     3481 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
     3541 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc
     3601 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
     3661 catcaatctt gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa
     3721 cttttttatg caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag
     3781 cagcaatacg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
     3841 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
     3901 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
     3961 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
     4021 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
     4081 tctccccaat caagactccg ccaggttcac gggtcgtcaa cacctctact cctttttcct
     4141 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
     4201 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
     4261 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
     4321 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
     4381 cgcagtttga atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta
     4441 cctcttattt acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg
     4501 tgcctcgaaa agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac
     4561 tacaaacttg atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag
     4621 ctcctaccac agtttgggct gccattttca aggctgtttc tcgtgataat cccgtctgaa
     4681 cacctgcatc tgccaaggct tcaataaaga gatagacaaa ggctggtcca cagcctgcaa
     4741 gacctgtcgc tgcattgatt aagctttctc ctaattcaac caagagacca gccttggata
     4801 aaagctgaca aaagagctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
     4861 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttgac
     4921 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
     4981 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
     5041 gcttaactcc tagaaaaatc acatctgctt ctgcaaacat ttcttcattg ctggaagcct
     5101 gaccaccaaa gtctgcaatg aaagcatcta ccttagcttg actacgattg gcaaggagaa
     5161 tctcatctga cgtcctagtc tgcaagacag attttgccaa gctagcaccc atattcccca
     5221 aaccgataaa tccaatcttc atctcttact cccttatctg cccatcacca gcaaccacat
     5281 acttgtagct ggtcaactct ttcaagccca ttggaccacg cgcgtgcaat ttctgagtag
     5341 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
     5401 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
     5461 ccgtcacaat agcatccgaa tgatgggtgc tgtgggattc aatgtgcgca accgcttctt
     5521 ctaaactgct cacaacctta acagcaagga catagtctaa aaactcggtg tcaaagtctt
     5581 gggtctcagc tgcttgacct gaaacaaact ggcttgcttt gctatccaag cggaattgaa
     5641 ttggttccaa cccagcttct tttcgatctg caaccagcac ttgctccaag cgaggaagga
     5701 agcttgctgc cttgtcttca tgaaccagca gaacctccat ggcattgcag acagaaggac
     5761 gactggtttt ggcattgttg atgatagaca gtgccttgtc gtcatctgcg tccttatcga
     5821 cataaacatg gacaatccca gttcctgtct cgataacagg cacaatggca ttctcaacca
     5881 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
     5941 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
     6001 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
     6061 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
     6121 catcagacgt cacatttgga cggctttcat agataatacc gatgacaccc atagctacac
     6181 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
     6241 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
     6301 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
     6361 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
     6421 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
     6481 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
     6541 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
     6601 gagaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
     6661 attttccact ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg
     6721 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
     6781 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
     6841 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
     6901 caatcatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
     6961 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
     7021 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
     7081 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa
     7141 ggtctgcttg gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttaa
     7201 gctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca
     7261 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
     7321 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
     7381 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct
     7441 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
     7501 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
     7561 ataaacttcc atcctcattt gtcagagaag aagtacccac cttaaagaca atccgtttgt
     7621 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
     7681 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctgttctgat
     7741 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
     7801 gttgaaaaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
     7861 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
     7921 tcgatcgaaa catccactaa ccaggcacca cttgaatcca cagtataacc ttctggtgtc
     7981 ttaccgttca caagtaattg accattttct ttcaagaagt accatttatc cttgtccttg
     8041 atccaaccca cagctcgtga accgtctgtc ttgtagaaat accaatcatt tgccttttta
     8101 tgccagcctt gcttcatagc tcctgaatct tccagataat aatgttgacc agcaacttct
     8161 atctcacctg tcttcatgac accagtagaa tccatatagt accaggtttc tttatctttt
     8221 acccagccca ttttcatttc ccctgatgga gcaaagtaat accattgccc catatattga
     8281 agccatcctg tcttcataga accatcaaca tccaaataat accactgctc tttatcttga
     8341 acccaaccaa tttccatctg attttctttg ttaaaataat accagattcc atcaattttc
     8401 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
     8461 ttccattgat tctgtaataa gatacccgtt tggttaaagt aataccattc acccttaatt
     8521 tcattccaac cgacaacata ctctcctgta gaatcaggcg cttgatacca ccagtttcca
     8581 tatgaactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga agttgaaatg
     8641 tttactaaac cgtcttgtcg aatatcaaaa actgttgcat catagtcttt gctggctgca
     8701 tttatatatt gaattcccat tgattcaagc caactaatat attccctatt tatttcttga
     8761 ccgctatcat acgaaccaat tggtgaggag gaagtttgaa caatcaaact cggactcaaa
     8821 tttttaatga aatccttggt atttgatttg ttggtatcat ggtgatgatt aaacttcatc
     8881 aaatcaactt ttccaatgag aggaccatac ttgtcttctg ctccatgaac attatctaag
     8941 tcgcccccaa ggtaaatttt cttgccattg acttttacca cactaatcaa ggaattggaa
     9001 ttatcatccc aaattttctt taattcacct gatgaatcgg tttcattttc atagttatag
     9061 agttgaatat ccatgtcccc aaactgaaaa tgagcatccc cttgtgtgat attttgaata
     9121 actgaaacac ctttttctga agcagtctgt aaaaccttat cataaccgta cagattatcc
     9181 catagacgtt cagaattagt aatacgatta tcactatatt tcttaagata gactcggtca
     9241 actggatagg tagacagtaa ttcatcaaca tttccaatat gatcactgtg ggtatgggtc
     9301 accaaaataa aatcaagttt ttggacaccc aattccttca aacgacgaaa gacacggtct
     9361 gttagaacat gcttataaga cgtttcaatt tcttctctcc atggatagcg agaatcactt
     9421 ccatctggga aatcataatc ttctcctgta tccaccatgg caaaatgtcc attgctttca
     9481 agaataatcg catcactgcc accttcttga acattgataa agtggatttt atttcctgaa
     9541 ctttcttgag cctgaacatt cccataccat gacaaaccta aaaaagcgcc tacaagtgct
     9601 aaactagtta atttcttttt cattcttact ttctcaatct ctccaaggtt tccttaaaaa
     9661 tctctgggat atctgcttta aattccaagg tcttacctgt tctcggatga gtaaaaccta
     9721 aagtcttggc atgaagaaat tgtccatgtc ctttcaaagt cttgcgagga ccatagacct
     9781 catcaccagc gactggatgg ccgatataag ccatgtggac acggatttga tgagtgcgcc
     9841 ctgtctccag ttgcaactct actaagctat aatcgccaaa gcgttccaag acgtgaaaac
     9901 gcgtcactgc aggcttccct ttagcagtta cagcctgttt cttacggtct ttttcactcc
     9961 ggccaatcgg cgcttcaatt acaccacgat cattaggcag atttccatga acaatcgccc
    10021 aatatttgcg gagagacttt ttatccttga gttcttgggc aagtgctaga tgcgcatcat
    10081 cgtttttagc aatcatgaga agacctgacg tatccttatc aatacggtga acaattcctg
    10141 gacgcagaac cccattgata cccgacaagt ccttaatatg atacatgagg gcatttacta
    10201 gggttccact ggtatgacca gcactcgggt gcacaaccat tccctgaggt ttgttaacga
    10261 cagccacatc ctcatcttgg tagactattt ctagcggaag atcctcagcc acatactcta
    10321 atacctctgg ttctggcaca tggtaagtga cgacatcacc ctcttggact gtgtatttag
    10381 ctttcttgac ttgaccattg accaagacct ggcctgattt aatttgttca ttcgcaagac
    10441 tgcgtgataa ttctgtcaaa tctgacaaag ccttatccaa acgcagacca ccagtttcaa
    10501 ttttaatttc catttatttc ctcttttagc attgcaatca ataaaataat cactccaacc
    10561 gtcagatagc tatctgccac attgaaaatt gcaaagttga taaagtcaag gtggaacata
    10621 tccacaacaa agccctgact ggccctgtca ataaagtttc caagaccacc cgcgattatc
    10681 aaagtcaaac ccaagaccat ccagaatgag tcctccatgt gtttatgtaa ataccaaatg
    10741 gcacctatca cgacaaccag agtaatgaca gcgaataaca gctgctgatc ttgtaagata
    10801 gaaaaggctg cacctcgatt ttgcaggtag gtcaagctaa cgaaattggg aatccaggag
    10861 cgcacttcac ccagtggaat ctgctggacg atataggatt tgaccaactg atccagccca
    10921 attaaaagca gtacaatgac tgccactatt gctctttttt tcatgatttc ctcttttgat
    10981 caaaatattc ttgcatgact tctacgaaga gagtcccagc ttgactaagc tccacttctt
    11041 cacgtttaac atagaccatg cggttatcta ggttatcctt gagacgaata actgtaatgc
    11101 cattaacact gtcactatct aaaaatccag aacctgtcgc ataggcgtcc gtccgctcca
    11161 aaataccatt caaggtggca cggtctgtca cattaaacat ctgtgagcta gcgctggtat
    11221 cgacaaagtt ctctgaataa taaaggtact cgtctttctc ttgagtgaaa cgaaccgttg
    11281 gtaaatccgc taaatcctcc atgactaatt cctctttccg agctaaagga tgaccctcac
    11341 agagataaat atgggtatgg aaaggaatca attcgatgac ctccagacct aacttttcaa
    11401 cccgttgcat aatccccttt ttattttgat tgttgaggta gataatccca atctcactat
    11461 gcccttgcgc cacttcatct aatatttgaa cagtagttga ttcaaaaata cggaagttct
    11521 tatagtcagg atagcgctct gaaaaggccg taatagttgg tggtaagaag tcatagtgct
    11581 ggctagcaac ggaaaattca tctttttctt cttcaggatt ggcatactga ttttgaaaaa
    11641 tatcaaatcc tttaaccaat tcttgcgctt tttcataaaa ttccatccca cgacgggtca
    11701 agaaagtccc tgagctggtc cgacggaaaa tcttaaagcc caactctttt tccaaatcac
    11761 gaacagaaat agacagactc ggctgactaa catacatctt ttcagcagct tcacgaaaag
    11821 taccactatt ggcaatagcc acaacatagc gtaattgttg aatgttcatc ttctaccccc
    11881 aacttcttta tctttttatt ataccatatt ttagaagttt tccaaaaagg aaaaaagaac
    11941 atcctattct tcttaactat cttcactatc tgcctttctc acgccaatct tattttcaaa
    12001 atcaattcaa aaaaataagt ggctacacac cacttcagta tcggaaagaa aaacgttgac
    12061 tatttgtgaa aaaagaaaat gccggaaaat tccgacattt tttagtaagc taacttcctg
    12121 aaaataggag taaccaaaca tcccagaaag cagtgatatt gatgagaata tgaactagta
    12181 ttggatagta gatgttttta gtcatgcgat acaatagagc caaaataaga cctccgctag
    12241 cataaatgaa aaaagcaaga ggagttaaag caaaattgat atgaatataa ccgaaaataa
    12301 tagcaaaaag caagacatct ccgtaccaag gcgagttttt gaaaaaggtt gtcataagca
    12361 caccgcgata aatcaattcc tcagcaatag ggccgatgaa gcaaacgatg agcaaaaaat
    12421 agggtaattc ctgtctccct atcatttcta tcgtttcatt caaagaaatt tgatttgaag
    12481 acagggatat gaaatacgaa aagagaaagt cagacatata cgaagtgatg taacccagta
    12541 aaaggtagat aaaatacctc agctgccact tgaaatgaaa agttttcttt cctgcaaaaa
    12601 ctagtagata gatgaccgct aataaaagaa ctccactctc catcaaaagc agaatctgaa
    12661 aaaattcacg acttgctggt agatagggct ttgcgagata attgaaaagc ctccaaaacc
    12721 aagttgattt gtaaaaaatt aaggacaatg ctagtaaaat ttgaatagcc cgttttttca
    12781 tattaaattc tctgctttct ccacttgttt cttcatatta ctaataaatt ttacttaaaa
    12841 tctcgcagca cttcctttgc aaagatgatt acctcctcca atatatccta aatcatcggt
    12901 gtctctggga caaaatccat gaaccagcag agttaatact ggttccattt tccaaggata
    12961 ataaccatta ggttctttac catagggatc tgctccacct tgtatcagct ctaattcttc
    13021 atttgttaga tttatatttt ttgtcattaa aatcatgata tatttcctcc gttattgttt
    13081 agattagttg agtaatctgc tactcatacc tacttacaaa aaaactatta tattaagttg
    13141 gttttttaat ttgtctagtt gcaacattga caaacatagt atagcatatc tttgccaaat
    13201 atcctcttca aatcatgaat tgtcatcaaa acatcttaaa ctataaaatc aattagtctc
    13261 aagctttcta tcaatttctt atccaaaata tgctataata ataccaaaag ataaagaagg
    13321 aagacctatg attaaactac tagccttgga tatggacggc accctcctca atgaagccaa
    13381 ggaaatccca caagctcaca ttactgctat tcacaaagcc attgaaaaag gtgtcaaact
    13441 ggttctctgt acgggtcgcc cccttttcgg tgtcctcccc tactacaaaa aactggggct
    13501 tgacctccag aacgaatatg ttattgttaa caacggttgt tcaactcacc aaaccagtga
    13561 ttggggtcta gttgactgga aagaactgag tccagctgac atcgaatacc tctatgacct
    13621 tgctgaaaag agtgatgttc agttgacact ttttgacgag tcacattatt ttgttctcgg
    13681 tggcaagccc aatcaagtta ttgaaaatga tgctaaacta gtattttcag acctgactga
    13741 aatttctctt gaggaagcga ctagtggaaa gttccggatg ttccaaggta tgtttttagg
    13801 aacaaaagaa caaacagacg attttgagca gcgttttgct gaagagcttt gccaacgatt
    13861 cagtggagtt cgttcgcagc ctgtcattta tgaagcaatg ccacttggaa cgacaaaggc
    13921 tactgctctt tcacgactag ctgagatttt gaagattgat tcctcagaga ttatggccat
    13981 gggcgatgct aataacgata tcgaaatgct ccagtttgca gggcttggga ttgcaatggg
    14041 aaatgccagc gattatgtca aatctcttgc ggatgccgtt acctcaagca acgaagaaga
    14101 cggcgttgcg cgtgctattg agaaatatat tctataaaaa agaaaagcaa atagacagaa
    14161 gttactgcta tttgcttttt tgctaatatt ttaaaatacg gactaatcaa tagacaagaa
    14221 tagcgaatca taaaaatcga tttactagat gccatagtat cttatagttg ctaataagaa
    14281 gttagtctag cagaatgaat ctctcatttc tcccacacta atctgtaatt tgtctataca
    14341 tttctggtct tctatctcga aacaagcccc agtttagacg ttcacttgct cccttgtcta
    14401 ggtcataagt agctaacaga acagcttctt cttgtctttc agctcgttct agaatagctc
    14461 ctgtttcatc cgtcataaag gaggaaccgt agaagtcaag actggaactc tgtccgccat
    14521 tttcctcact aggagtaacc tcctctaaac cataacgatt ggctgcgatg actggaacaa
    14581 tattcgctgc tgcgtgccct tgcatagtac gttgccagtg accacaacta tctgtatcca
    14641 aaattggctc tgaaccgata gctgtaggat aaaagagcaa ttcagcacca ttcaatgcaa
    14701 gacagcgcgc tgtttcaggg aaccattgat cccaacagat accgatacca atcttagcat
    14761 agcgagtatt ccagaccttg aaaccagtgt taccaggcgt gaaatagaat ttttcttgat
    14821 aataatggtc atctggtata tgggtctttc gataaacgcc cagcacttcc ccatctgcat
    14881 caatgacggc aatagagtta tacaagacat taccatcttt ttcatagaaa ctgattggta
    14941 aaacaacttg tagttcctta gcaatcacct taaaatgctg aatggcagta ttttccgcta
    15001 cagattgggc atactggtag tagtcatact gacgttcctg acagaaatag ggatgttcaa
    15061 acaactcggg caagagaata atttgggctc cttgctcagc agcctgacgt actaaacgct
    15121 ctgcggtttg gatatttgtt gccacatcct tagcgcattg catctgaatg gttgcaactc
    15181 ttacatttct catctttttc tcctattctg gaatttgttg ggtgatacag tggatattgc
    15241 caccacctaa gagaatatct ctggctggta ttccgacaac tttacggtct gggaaacact
    15301 tgctgaggat atctaaggcc acttggtcgt ttacatcctc aaactgtgga accaagacag
    15361 ccttgttggc gatataaaag tttacgtagg aagctgctag tcgttcacct gcgtatcgct
    15421 cttcttctcc ttcttcatag atgtagcctg gcaaatcttc ttctgtcaca acttgtcgaa
    15481 ctgcagggat aggcaattta tgaatggtga agtgacaacc ttttgcatct gtttcctgtt
    15541 ctaagagttc gagatctgct tttgacatgg catactgggg atcattttcg tcatctgtcc
    15601 aagccaaaac aacctcagca ggaccaacaa aggcagcaac attatcgacg tgttcattgg
    15661 tttcatcctg ataaatacca taaggaagcc aaataacttt ttcagcacca agactttcta
    15721 ataatgtgtt ttcaatctcc tctttagtca agttaggatt gcgaccagga ctaagcaagc
    15781 aactttcagt tacgagaata gttccttgac catcgctatg gattgcgcct ccttccagta
    15841 caaaaggttt agcatcatag acaggccttt ccaaggcctc agcaaaacga ctggctactt
    15901 ggtcatcctc ttcataatct tgataaagac catcataggt gcctccccaa gcattgaagg
    15961 cccaatccac ggctaatttc ttacctttgt cattgacgag aatggttggg ccagtatcac
    16021 gcgcccaggc atcattggtg ggaatgtcta aataaacaac cttgtctcca agataggatt
    16081 gggcttcaga tagataggcc tgctccacca aaagatagac tctttcccct tctgctatag
    16141 tctcgatgat ctgagtaaat gctcttttag catcctttcc ttgaaaaggc catgatcctg
    16201 gtcgagtcgg ccatatcatg agggtaccat gatggggttc gtactctgct ggcatgtgat
    16261 agcctaattt ttttggactg tccatcatga taatctccct ttaaagtctt gatagccaaa
    16321 agctttgagt aagctacagt ctccctgttc gtccatgaga tagagacttg gcaatccaat
    16381 accattaaag gtattatttt tgacaaaaga ataaatggcc atgtcttgaa aataaagtct
    16441 gtctccgatt tggactggat tttcaaaact ataatcacca atcacatcgc ccgtcagaca
    16501 ggtattagaa gaaagtctgt aggtatgggc tttttcctgt gcctcaaagc catttctcaa
    16561 aggtggacga tagggcatct caagtacatc aggcatatgg caggtcgcag aggcgtctaa
    16621 aaccaagatt tccataccgt tttctacaat atctaatacc tcagttgcta aataacccgc
    16681 attaagcgca atggcttcac caggctcgat atagatttca agattgtaag tttttcggat
    16741 acgcttgatt tctgaaatca gcaaatccac atcgtaacct tctcttgtaa tatgatgacc
    16801 accacccata ttgagccatt ttacctcatg taagtaggga ccaaactgtt cttctactgc
    16861 tttcaaagtt gtttgtaaat catctgctcc ctgctcgcaa agggtatgaa aatgaagtcc
    16921 gtcaaccaaa tctagcaaat cactcggaat cttgtctata gtaactccaa agcgagaacc
    16981 tggtgcacaa gggtcataga gcgcgtgatc tccttgagtt gaacactgag ggttgaggcg
    17041 caaaccaaca ctgacaccag cctctcgaca acgcgaacca tgcttacgca actgtctctc
    17101 tgagttaaag acgatatggt ctgttatccc aagcaattcc tccatgtcct catccttgaa
    17161 agctggtgca aaaacatgga cttcaccagg aaattcttcc cttgccaatt tggcctcata
    17221 gagtccacta gctgtcgtac ctgatagata ctggctaatc aagggataag ttttgtagag
    17281 ggaatatgcc ttctgggcaa gcaagacctt gcaaccggcc tcttcttgta catattgtag
    17341 aatgcggcaa ttagcttcta acttggccaa gtcaataaca taggctggtg ttggtacttg
    17401 ttctaacttc attagtccac catttgtgga ttttcaacca caacccatgg caaaccatac
    17461 tcattcaaag cttccatgaa tggatctgga tctaactcct caaggttata cactccagct
    17521 tgtttccaag ttccgttcat gactaatttt gtcccaatca tggctggaac tcctgtcgta
    17581 taagaaatag cttgcgaacc aacctctgcg taacattcct gatggtcgca gacattgtag
    17641 atatagatag tctttttgac accgtctttg acacctgtaa agatacatcc aatattggtt
    17701 ttacctacag tacgtggacc aaggctagca ggatctggaa gcaaggcttt caaaaattga
    17761 attggaacaa tttcttggcc gttaaagtta atggtatccg tacgaaggag tccaacattt
    17821 tcaagacatt tcatgtgcgt caagtaagat tgaccaaaag tcataaagaa acgaatgcgt
    17881 ttgacacctg gaatgttctt ggccaatgat tcgatttctt catggtgaag gagatacata
    17941 tctttttgtc caacttgagg gaaatcatac tcacgcttga tagacatagc ttcgacttcg
    18001 acccatttcc catcttccca gtaagaacct ggcgcagaaa cctcacggag attaatttct
    18061 ggattaaagt tggttgcaaa tggataaccg tggtcaccgc cattacagtc taaaatgtcg
    18121 atataatgga tttcatcaaa atagtgtttg agggcataag ctgaaaagac actagttaca
    18181 cctgggtcaa aaccagaacc aagaagagca gtcaagcctg cttctttgaa tttctcttga
    18241 taagcccact gccatgagta gtcaaagtag gctgtaaaac caagttcctt acaacgtttt
    18301 tcgtagatag cacgccactc agggtcttct gtgtcttctg cttcgtagtt ggctgtatcg
    18361 atatagtgaa cacctgttgc caaacaagca tccataatgg ttaaatcttg ataaggcaga
    18421 gctacattca aaacagcttc tggtttgtag ctttcaatca gagcaatcac ttcttcaacc
    18481 ttgtcagcat caagagcagc tgtctcaatc tttgtacttg ttttgccttc cagtttagct
    18541 ttcaagtcat cgcattttga cttggtacgg ctagcaatca taatctctgt aaatgtttcg
    18601 ctatcttgac aaatctttga aatagcaact tgggcaacgc ccccacaacc aataactagt
    18661 aaacgactca tttttttcct tcctcttctt ctaaaatgtc ctcaacatac ttgggcaaca
    18721 taaaggctcc cacgtgtaag tttgcagtgt agtattctgt gaaaagctgg cgttttttcc
    18781 agccttcctt gtcaaaatct ttgacagggt ggtatttttt cgatgcaaat ccaaacaacc
    18841 aatagccagc tgggctagtt ggaatatggg cctgataaac ccgactgatt ggaaaggctt
    18901 gattgacctt gcggtgcatg cttcggcagg ccgactcatc ctcgtcaaag aacggactcc
    18961 catgctggta aatcatgatg ccgtcttcct tcagagctcg ataactattg ccgtagaatt
    19021 ccttggtaaa gagtccttcc gtatggccaa atggatctgt cgcatcgttg atgataatat
    19081 catagtcata ttcgcagttt cgcaaaaagc gtagcccatt ttggtagtaa atggtaacac
    19141 gaggatcatc taggcctgca gcaaagtctg ggaaatactc acgacagacc tcgaccaaca
    19201 tctcatccgg ttccacgata tcgatttgtt ccagttcagg atagagtgtt aatacttggg
    19261 caacaccgcc gtcaccaccc ccaataacca atactttctt tggatttggg tggacagcca
    19321 tgggaacgtg aacggtcatt tcattgtaga cgaaatcatc cgcatctgag aacaagacat
    19381 ggccatttaa aatcagtatt ttcccaaaag ctggcgtatc caagacttcg atatcctgcc
    19441 attcactttt tccagcgtaa agttgcttgg ctgttctcag agacaatttg acatctggag
    19501 tatgaacttc agaaaaccat aaatccatct atttctcctt atattatatt tagcgcagtt
    19561 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
    19621 ctccaatcgc ttgacgattt ccgaaagggt ctaaccacag ctttttgttt caattggtaa
    19681 tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg
    19741 gataaccaag tagacttgaa atactatatc tggaggta
//
LOCUS       DBEJZJ010000037        15597 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000037 DBEJZJ010000000
VERSION     DBEJZJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.37"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="ACL3R8_001665"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="ACL3R8_001665"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR1314513.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYVQANLDSSQD"
     gene            1317..2021
                     /gene="yycF"
                     /locus_tag="ACL3R8_001666"
     CDS             1317..2021
                     /gene="yycF"
                     /locus_tag="ACL3R8_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR1314514.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="ACL3R8_001667"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="ACL3R8_001667"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR1314515.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="ACL3R8_001668"
     CDS             3365..4174
                     /locus_tag="ACL3R8_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR1314516.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /gene="relB"
                     /locus_tag="ACL3R8_001669"
     CDS             4265..4507
                     /gene="relB"
                     /locus_tag="ACL3R8_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR1314517.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="ACL3R8_001670"
     CDS             4509..4763
                     /locus_tag="ACL3R8_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR1314518.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5553
                     /locus_tag="ACL3R8_001671"
                     /pseudo
     CDS             4810..5553
                     /locus_tag="ACL3R8_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(5854..6840)
                     /locus_tag="ACL3R8_001672"
     CDS             complement(5854..6840)
                     /locus_tag="ACL3R8_001672"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR1314519.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL3R8_001673"
     CDS             7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL3R8_001673"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR1314520.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9502..10245
                     /gene="srtA"
                     /locus_tag="ACL3R8_001674"
     CDS             9502..10245
                     /gene="srtA"
                     /locus_tag="ACL3R8_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR1314521.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10490..11287
                     /locus_tag="ACL3R8_001675"
     CDS             10490..11287
                     /locus_tag="ACL3R8_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR1314522.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11435..12694
                     /locus_tag="ACL3R8_001676"
                     /pseudo
     CDS             11435..12694
                     /locus_tag="ACL3R8_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            12790..14064
                     /locus_tag="ACL3R8_001677"
     CDS             12790..14064
                     /locus_tag="ACL3R8_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR1314523.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14076..>15597
                     /locus_tag="ACL3R8_001678"
     CDS             14076..>15597
                     /locus_tag="ACL3R8_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGR1314524.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFE
                     KRRLDFEKGYFKNLLPYSIVNQTVESLASLNAIFITSNYDYEIENHIKRLKNAVVTIN
                     DLNEFTKNKNGKLQFGDVLHIHGTPDCDVKYFVSSSADYSKTYLKNRENFENLVTWFK
                     ETKPTVLFVGAGLEEDEILSLLCKDSKNYALMKSENTGNQRVDEHYRGVVEGFFSSEN
                     HTQIIWYGDEFEKLPLFVKKLVADINEKLGTHDFYNQWNNLLNPSINQEEYNKNLDSI
                     SNDFKYLSSVLDKVIENDNNQLDQLMLNALLRSETLTVIKKNFVLAFWRFIVKNIEKL
                     SDNEWDVIYKIIYEGSQNYFIDDVFFVYNYAIDNKISSFTNNNKLNELREIISKDGYI
                     VNSNFNKDKTLLGYWLVSAFEQQNRDLYIKEDSEVEVNLNYECVNKLMSILNNPEFL"
BASE COUNT         4935 a         2598 c         3381 g         4683 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgt ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggtcccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg tacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tgggcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 actaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattattaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagca tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtggat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg caagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttgggcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg acctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacccaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagattt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaagacccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt tgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattcaag ctgagtaata acagtataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttggctattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa
     5701 taaaatctga acaaatcaat taggaattta aagcatttta taacaacgtt ttagagtaat
     5761 ggggtgctat ttcaacttca acctactata atacagaaaa aaatacagaa aaaaacaact
     5821 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
     5881 tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt
     5941 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
     6001 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
     6061 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
     6121 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
     6181 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
     6241 ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
     6301 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
     6361 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
     6421 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
     6481 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
     6541 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgattac
     6601 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
     6661 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
     6721 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
     6781 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
     6841 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
     6901 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
     6961 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
     7021 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
     7081 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
     7141 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
     7201 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
     7261 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
     7321 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
     7381 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
     7441 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
     7501 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
     7561 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
     7621 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
     7681 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
     7741 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
     7801 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
     7861 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
     7921 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
     7981 cctcttcaaa atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa
     8041 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa
     8101 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
     8161 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
     8221 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
     8281 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
     8341 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
     8401 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
     8461 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
     8521 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
     8581 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
     8641 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
     8701 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
     8761 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
     8821 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
     8881 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
     8941 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
     9001 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
     9061 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
     9121 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
     9181 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
     9241 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
     9301 tgatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
     9361 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
     9421 tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa
     9481 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
     9541 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
     9601 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
     9661 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
     9721 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
     9781 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
     9841 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
     9901 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
     9961 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    10021 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    10081 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    10141 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    10201 gaaatcctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    10261 tcatggattt cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat
    10321 aggacgaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt
    10381 actattctag tttcaatcta ctataaactt ttatgaaata tagaaaacgc ttcctaaaac
    10441 ctaaagtttg tgatataatt atcaagaaaa aaagatttag gagtttatta tggtttcttc
    10501 agaatttatc tcaaagattg aatttgcttg caataagaaa gaaagtcttt atagtcaaag
    10561 caaatttaag tatgcgattc gttcgatgtt cgcaggtgca tttttaacct tcagtactgc
    10621 tgcaggtgca gttggggctg acttgattaa taaaattgca ccaggtagcg gacgcttcct
    10681 ctttccattc gtttttgctt ggggcttggc ctacattgtt tttttgaatg ccgagttggt
    10741 cacttcaaac atgatgttct tgactgctgg tagtttatta aaaaaaatct cttggagaaa
    10801 aacagctgag attttactat actgtacctt gttcaacctt atcggagcct tgatagcagg
    10861 gtggggcttt gctcattcgg cagcctatgc gaatctgaca cacgatagtt tcatctcagg
    10921 ggttgtagag atgaagttag gccgctcaaa tgaattggtc ttgcttgagg cgattttggc
    10981 aaatattttc gtaaacattg ccattctttc atttattttg gtcaaagatg gtggtgccaa
    11041 actttggctt gtgttgtcag ctatttacat gtttgtattc ttaacaaacg agcacattgc
    11101 ggcgaacttt gcttctttcg cgattgtgaa attcagtgtt gctgcggatt caattgccaa
    11161 cttcggtgtt ggaaatatgc ttcgccactg gggtgtgact ttcatcggaa actttatcgg
    11221 aggaggcctc ttgatgggtc ttccatatgc cttcctcaat aaaaacgaag atacttatgt
    11281 agattaagaa aatgagcacg attgagtcgt gcttttttca ttttcaaaat aagataatag
    11341 ctatttctta tatcaaaata tagaaaactg atatttgtaa actataactc aaggtgctac
    11401 aatatcctta ataaaataat atggaggtca ccttatgact cgtgatttta aatttgaaac
    11461 tctacaacta catgctggtc aagttgtgac tccagctact aagtctcgtg cagtgccgat
    11521 ttatcaaaca acatcttttg tttttgatga cacgtaggaa ggtgctgatc tgtttgcctt
    11581 gaggaaacca gggaacattt atactcgtat caccaatcct acaacagctg cccttgaagg
    11641 tggtgttgaa gcgctagcaa cagcatcagg tatgactgca gtgacttata cgattttggc
    11701 gcttgcccat gctggtgagc atgtagtggc tgcttcgact atttacggtg gaaccttcaa
    11761 tcttttgaaa gaaccccttc ctcgttatgg tatcacaaca acctttgtcg atgttgataa
    11821 tttggaggaa gtagaagcag ctatcaaaga caataccaag cttgtcttga ttgaaacctt
    11881 ggttaacccc ttgattaata ttccagacct ggaaaaactg gcagagattg ctcataaaca
    11941 tcaaatccca cttgtgtcag acaatacttt tgcaacacct tatttgatta acgtcttctc
    12001 tcatggcgtt gacattgcca ttcactctgc gactaagttt atcggtgggc atggtacaac
    12061 tattggagga ataattgtcg atagtggtcg ttttgactgg acggcttcag ggaaattccc
    12121 tcaatttgtt gacgagagtc caagctgcca caatttgagc tatactcatg atgtgggtgc
    12181 agcagccttt attatagctg ttcgagttca attgcttcgt gatacaggtg cagccttgtc
    12241 accattcaat gctttcctct tgctacaaag acttgaaacc ctttcacttc gtgtggaacg
    12301 ccatgtacaa aatgctgaga caattgttga ttttcttgtc aaccatccta aggtagaaaa
    12361 ggtaaattat ccaaaacttg cagatagtcc ttattatgcc ttggctgaga aatacttgcc
    12421 aaaaggtgtc ggttcaatct ttaccttcca cgtcaaaggt gacgaggagg aagcacgcaa
    12481 ggtcattgat aatttagaaa tcttttctga ccttgcaaac gcggcagatg ctaaatcgct
    12541 tgttgtccat ccagcaacaa tcactcacgg tcaattgtca gaaaaagacc tagaagcagc
    12601 aggtgtcaca ccaaatcaaa tccacttgtc tatcggtctt gaaaatgtag aagatttgat
    12661 tgaagactta cgcttggcct tggaaaaaat ttaaagtaaa agaagataaa cagtgggttt
    12721 tgactcactg tttttgattt tccctcaggc atgatataat ggttacagaa gtctagaaag
    12781 aggaatgtaa tgaacgaaat caaatgtccc aactgtgggg aagtctttac agtaaatgaa
    12841 agccagtatg ctgaactttt gtcccaagtg agaacggcag agtttgataa ggaactacac
    12901 gataggatga ggcaggaact ggccttggct gagcaaaagg ctatgaatga gcaacagact
    12961 aaactggctc agaaggatca agaaattgcg caattgcaga gtcaaatcca aaactttgat
    13021 acagaaaaag aattggccaa gaaagaagtt gaacagacaa gccatcaggc cttattggct
    13081 aaggacaagg aagtacaggc cttggaaaac cagttggcga ccttgcgttt ggagcatgaa
    13141 aatcaattgc aaaagaccct ttctgaccta gaaaaagaac gcaatcaggt caaaaatcag
    13201 ctcctactgc aagaaaagga aaatgagttg tctttggctt ctgttaagca aaactacgaa
    13261 gcccagctca aagcagccag tgaacaagtc gagttttata agaattttaa ggctcaacaa
    13321 tctacaaaag cgattgggga aagcctagaa cagtatgcag agagtgagtt taacaaggtt
    13381 cgtagtttcg cctttccaaa tgcttacttt gagaaggata acaaggtctc ttcgcgtggg
    13441 tctaaagggg actttatctt ccgtgagtgt gatgaaaatg gagttgaaat catttctatc
    13501 atgtttgaga tgaaaaacga agcggacgga acagagaaga agcacaagaa tgcagatttt
    13561 tacaaggaat tggacaagga ccgtcgggag aagaactgtg agtatgccgt tttggtgacc
    13621 atgcttgagg ctgataatga ctactttaac acagggattg ttgacgtcag tcacgagtat
    13681 gaaaaaatgt atgttgttcg tcctcaattc tttatccaat tgattggtct cttacgtaat
    13741 gcggcgctaa attccctaaa atacaagcag gagttggcct tggttcgcga gcaaaatatt
    13801 gacattacgc attttgagga agacttggat gcctttaagc tagcttttgc taagaactat
    13861 aattcagctt cgactaactt tggaaaagct attgatgaaa tcgacaaggc catcaaacgc
    13921 atggaagagg ttaagaaatt cctgactaca tctgaaaacc aactccgtct agctaacaac
    13981 aaattggaag atgtctctgt taaaaaattg acccggaaaa atccaacaat gaaagcgaag
    14041 ttcgaagcat tgaaggggga gtgaggaaat aagttatgga agatgatctt aattatgaaa
    14101 atttgatgga tgatgtaacc gaggctataa aaaagtttaa cttagtaatt tttattggcg
    14161 caggagtttc aattgctcaa ggttatccta attggaacaa ttatattgaa catcttatta
    14221 agtattggca aggacaagtt ttatcggtaa gtggtgaaaa aaggcttgga agagaacatc
    14281 acgtagtttt tgatttaatt agcaaatcta gtattagtaa taaacgtaaa gtggatcttg
    14341 taaactatga attaaaaaaa gtttttggtg aagattttga aaagcgacga ctagattttg
    14401 aaaaaggata ttttaaaaat ctattaccat attcaatagt taatcaaaca gtagaatctt
    14461 tagcaagttt gaatgcaata tttattactt ctaactacga ctatgaaatt gaaaatcata
    14521 ttaaacgttt aaagaatgct gtagttacta ttaatgatct caatgaattc actaagaaca
    14581 agaatgggaa actacaattt ggtgatgttc tacatatcca tggaacacca gattgtgatg
    14641 taaagtattt tgtaagttca tccgcagatt attcaaaaac ctatttaaaa aatagggaaa
    14701 attttgaaaa tttagtaaca tggtttaaag agacaaaacc tactgtttta tttgttggag
    14761 caggtcttga agaagatgaa attttatctt tactttgtaa agatagtaag aactatgcct
    14821 tgatgaagtc agagaacaca ggtaatcaga gagttgatga acattataga ggtgttgttg
    14881 aaggattttt tagctcagaa aatcatactc agattatttg gtacggagat gaatttgaga
    14941 aactacctct ttttgtaaaa aaattagttg ctgatattaa tgaaaaattg ggcacacatg
    15001 atttttataa tcagtggaac aatcttttga atccttctat aaatcaagaa gagtataata
    15061 aaaatctaga tagtatttct aatgatttta agtatctaag ctctgtttta gataaggtta
    15121 ttgaaaatga taataatcaa ctagatcagc taatgttaaa tgctctgctt cggagtgaaa
    15181 ctctaacagt aattaaaaaa aattttgtcc ttgcattttg gaggtttatt gttaagaata
    15241 ttgaaaagtt aagtgataat gagtgggatg tgatttataa aataatttat gaaggctctc
    15301 aaaattactt tatagatgat gtattctttg tctataatta tgcgatagat aataaaattt
    15361 ctagttttac aaataataat aagcttaatg aactgagaga aattatatcc aaagatggat
    15421 atatcgttaa ttctaacttt aataaagata aaactctttt gggttactgg ctagtaagtg
    15481 cttttgaaca gcaaaatcgt gatttatata taaaggaaga tagtgaagta gaagttaact
    15541 taaattacga atgtgttaac aaattaatgt ccatactaaa taatccagaa tttttaa
//
LOCUS       DBEJZJ010000038        13569 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000038 DBEJZJ010000000
VERSION     DBEJZJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.38"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            536..1882
                     /gene="gdhA"
                     /locus_tag="ACL3R8_001679"
     CDS             536..1882
                     /gene="gdhA"
                     /locus_tag="ACL3R8_001679"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR1314525.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2378..2548)
                     /locus_tag="ACL3R8_001680"
     CDS             complement(2378..2548)
                     /locus_tag="ACL3R8_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314526.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2561..3202)
                     /locus_tag="ACL3R8_001681"
                     /pseudo
     CDS             complement(2561..3202)
                     /locus_tag="ACL3R8_001681"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3327..3513)
                     /locus_tag="ACL3R8_001682"
                     /pseudo
     CDS             complement(3327..3513)
                     /locus_tag="ACL3R8_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845777.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3474..3992
                     /locus_tag="ACL3R8_001683"
     CDS             3474..3992
                     /locus_tag="ACL3R8_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1314527.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTDEKEVNHLI
                     KYAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHTKYQKTQTDFQQEI
                     KVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKIDVEPVFGQIKA
                     SLGYKRCNLRGK"
     gene            complement(4213..4359)
                     /locus_tag="ACL3R8_001684"
                     /pseudo
     CDS             complement(4213..4359)
                     /locus_tag="ACL3R8_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(4292..4693)
                     /locus_tag="ACL3R8_001685"
     CDS             complement(4292..4693)
                     /locus_tag="ACL3R8_001685"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR1314528.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLTRSYPQTKDSCSLERSLGSKFG"
     gene            complement(4962..5450)
                     /locus_tag="ACL3R8_001686"
     CDS             complement(4962..5450)
                     /locus_tag="ACL3R8_001686"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HGR1314529.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            complement(5455..6864)
                     /locus_tag="ACL3R8_001687"
     CDS             complement(5455..6864)
                     /locus_tag="ACL3R8_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314530.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            complement(6874..8856)
                     /locus_tag="ACL3R8_001688"
     CDS             complement(6874..8856)
                     /locus_tag="ACL3R8_001688"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HGR1314531.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            complement(8869..9720)
                     /locus_tag="ACL3R8_001689"
     CDS             complement(8869..9720)
                     /locus_tag="ACL3R8_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314532.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            complement(9737..10687)
                     /locus_tag="ACL3R8_001690"
     CDS             complement(9737..10687)
                     /locus_tag="ACL3R8_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314533.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            complement(10797..12425)
                     /locus_tag="ACL3R8_001691"
     CDS             complement(10797..12425)
                     /locus_tag="ACL3R8_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR1314534.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDFSESGKEKVFYL
                     SGFLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGDFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLSKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            complement(12507..13430)
                     /locus_tag="ACL3R8_001692"
     CDS             complement(12507..13430)
                     /locus_tag="ACL3R8_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HGR1314535.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETC
                     IGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNE
                     IVYNKAVIDLATPGYREEYFSKGRDFFNWNRSMRILDLETGKVKIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            complement(13454..>13569)
                     /locus_tag="ACL3R8_001693"
     CDS             complement(13454..>13569)
                     /locus_tag="ACL3R8_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR1314536.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
BASE COUNT         4421 a         2541 c         2049 g         4558 t
ORIGIN      
        1 aataaattga aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg
       61 actgtcctaa tcgatttgtc ctgttcttgt ttcattttac tatagaacga tttgaaggcg
      121 tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggctt ggatttcttc
      181 tttagttgat ttcatatcac tattatataa tgatttttga ttttagtctg gtataaatat
      241 tgctttcctc caaaatggtc ataattttac tagcaaatct aacatatcac ggataaatta
      301 acaagtgatt tctgaattac taaacatttt cttttcttat agcataccat actttaagat
      361 tttgtctttg agaaagatat ttccaagaaa aacgttcgtt tttttatcta ttttcaaaaa
      421 aaccaaaaac tgaattgaaa gaatttttag aaaatttctg ttttttcttt acagtgaaaa
      481 aaaattctgc tataatgtct tatgtaataa aatatgacaa taaaaggaga acgatatgac
      541 atctgctaaa gaatatatcc aaagcgtgtt tgaaactgtg aaagctcgta acgggcacga
      601 ggctgaattc ctccaagctg ttgaagaatt tttcaacact ttggaacctg tatttgaaaa
      661 acaccctgag tatatcgaag aaaatatctt ggcacgtatt actgagcctg agcgcgtggt
      721 ttctttccgt gttccttggg ttgaccgtga tggaaaaatt caagtaaacc gtggttaccg
      781 tgttcaattc aactcagctg ttggaccata caaaggtgga cttcgtttcc acccaactgt
      841 aaaccaaggg atcttgaaat tcctcggatt tgaacaaatc tttaaaaatg tcttgactgg
      901 acttcctatc ggtggaggta aaggtggatc agacttcgat cctaaaggta aaacagatgc
      961 tgaagtgatg cgcttctgcc aaagcttcat gactgaattg caaaaacaca tcggaccatc
     1021 acttgacgta cctgctggtg atatcggtgt tggtggacgt gaaattggtt acctttacgg
     1081 tcaatacaaa cgtcttaacc aatttgatgc tggtgtcttg actggtaaac ctcttggatt
     1141 tggtggtagc ttgattcgtc cagaagcaac tggttacggt ttggtttact atactgaaga
     1201 aatgctcaaa gctaacggta acagctttgc tggtaagaaa gtcgttattt caggttctgg
     1261 taacgttgct caatatgctc ttcaaaaagc aactgaactc ggtgcaactg ttatttctgt
     1321 ttctgactca aatggttatg tcatcgatga aaatggtatc gacttcgatc ttttggttga
     1381 tgttaaagaa aaacgtcgtg ctcgtttgac tgagtatgca gctgaaaaag caactgcaac
     1441 ctaccacgaa ggtactgtat ggacttacgc tggaaactat gacattgctc ttccatgtgc
     1501 cactcaaaac gaaatcaacg gtgaagcagc taaacgtttg gttgctcaag gcgttatctg
     1561 tgtatctgaa ggtgccaaca tgccgagcga ccttgatgcc atcaaagttt acaaagaaaa
     1621 tggtatcttc tacggacctg caaaagctgc caacgctggt ggtgtagccg tttcagctct
     1681 tgaaatgagc caaaacagtc ttcgcctctc atggactcgt gaagaagttg atggccgtct
     1741 caaagacatc atgacaaaca tcttcaacac agctaaaacg acttcagaaa catacggtct
     1801 tgataaagac taccttgcag gagctaacat tgctgccttt gaaaatgtag caaacgctat
     1861 gattgcccaa ggtattgttt aagatttatt tgcttaatcc tcaatcacta cgattgggga
     1921 tttttagttg agttagacag ttgggaaatt ctaattaaat gaaataaaaa ctgaacaaat
     1981 tgattgcgga attcaaacca atttctaaca tacttctaga aattaatttg acttttctaa
     2041 tcgatttgtt catatcttat ttcaatttac tatacttact taaccctttt tatactcaat
     2101 gaaaatcaaa gagcaaacta ggaagcgagc cgcaggctgt acttgagtac ggcaaggcaa
     2161 agctgacgtg gtttgaagag attttcaaag agtattaaac aaaaagaaaa accgctactc
     2221 ctaagaatag cgatttaatc atgtttttaa gctactactg tagttgctct attatttaag
     2281 tgttatgaat aacttcaata tctttaaagc tttttgttag atttataatt tcaactatag
     2341 ccatctctac tccttagttt acagcaaaaa attatgctta attcttattg tttttgtaaa
     2401 caatcagcga acccaatact attccattca acaagcctaa agaaatacca tattcaactg
     2461 gaaaatctaa aaaaattgca aacactattc caatcatcac ccctagtgag gctattgtta
     2521 aaattacata ttcattttct ttcttcattt tctttacacc tcatttcctt tttgtatata
     2581 agctgtagta ctctccacca agagtcatta agtacttatg atttcctgac tcaacaatct
     2641 taccaccttt cattacaaaa ataatatccg catccttaat cgttgacaat ctatgagcta
     2701 taattatttg agtacaaccc tgactttgta tatactttgt tattctttcc tcattaatag
     2761 tgtctaatgc actagttgct tcatctaaaa ttacaatact aggattattt attaatgcac
     2821 gtgccagtgc tatccgttgc ctttgcccac ctgaaatatt tgaccccatc tctgagatga
     2881 tagtattaaa tttcatcggc atagccatga tttcatcata gatttgaact gctttacaaa
     2941 cttcctctat cttttgtgaa gtaacttcgt gctttaaagt tatattatca agaatacttc
     3001 tgttcaataa aaacgaatcc tgtggaacta ctcctaaatt ttgacttaat atttttttat
     3061 ctatttaatt aatatttaca ccatcaaata aaacttttcc tgtatcaatc ttatataatc
     3121 ctgatggtat ttttgataac gtactttttc ctgaccccga ttgaccgact agtgcaattc
     3181 tctgtcctgg ctcaatagtc aaatttaaat tttctattac aggagctgag tctttggaat
     3241 aagagaaaga taggtcctta atatctattc tacttcaaac gtttctaaac tatactccgg
     3301 aaaataattt aaccaataac tatctttcat cgtatcctcc aaccagtact aagagtctgg
     3361 gacaatagtc tcttatctcc aaaaaaaagc ggatttgccg ttgctttttt gcatggttgc
     3421 gatagtcttg gtaaaataga attgcccaat aaaccattta gaaaggctat cccatgcata
     3481 ttcactataa cacaaatcaa acaactttac cactagaaat cagttctttc ttgccgcaag
     3541 accatctcgt ctttactatt gaaaaagtgg tgaataccga tgaaaaggag gtaaaccatc
     3601 tgattaaata tgccatgttt gataaggaac aaaagagagg ctataaacag tcagctagaa
     3661 acttagcgaa ttggcactat aatgacaagg aggatagcta tacacatcct gatggctggt
     3721 attatcgttt tcaccatacc aaatatcaga aaacacagac agactttcaa caagaaatca
     3781 aggtttacta cgccgacgaa cctgaatcag cccctcaaaa gggactgtat atgaacgaac
     3841 gctatcaaaa cttgaaagct aaagaatgtc aggcgctttt atctccccaa ggtagacaga
     3901 ttttcgctca acgcaagatt gatgtggaac ctgtctttgg gcagataaag gcttctttgg
     3961 gttacaagag atgtaatctg aggggcaagt gagaattgac atgggattgg tacttatggc
     4021 caataacctc ctaaaataca ataagagaac gactcaaaat taaaaagcta gagttccaca
     4081 attggaaatc tttagctttt ttgtgattga gaactatttt gtcctagact cttttgattt
     4141 ttaaagagaa cttaaatcat tctctaatta aagtaggaag aatacactaa tttagtaaag
     4201 taaatattaa atttatttta ttttaaaatg atagtaggct ccaagcatac cagcagtgtt
     4261 ttgatgatga gcaaattcta atcttgtgtt ctcagccaaa cttggaacca agacttcttt
     4321 caaggctgca cgaatctttg gtttgaggat agcttcttgt taatagaaag actaaggtat
     4381 caggctcaca aaattctacc ataacttgac gacaaatgtt gcatggtggt aagtagtctt
     4441 cagtttcacc tgcaacagca atcgcaagaa tatctccttt tctatatcct tgagaagccc
     4501 cataaaaaat agcactacgt tctgcacagt tagttacacc aaacgataca ttttctatat
     4561 ttgctcctgt aattacttta ccatctttaa ataaaattgc tgcacctaca ggaaatttgg
     4621 aatacggaca gtaagcattt tttaaaactt tttttgcttg ctccattaaa acaaatttat
     4681 taattactgt cattgtttta actcctttat tattatattt tactcacact aaattatagt
     4741 aaaatgaaat aagaacagtg caaatcaatc aggacagtca aatcgatttc taacaatgtt
     4801 ttagaagtag agatgcacta ttctagtgta aaaaagtgag atatataatc cctcatttta
     4861 tgcggaaaat atatttggtt tctagattta tcattatcca atttgaatga caataatcta
     4921 gaaaccaaac gctttattat ttacgatact aaattcaata gttatatttc atcactagca
     4981 tgattgtgtg caattttact acatgctgct gcggctattg caccaacaat atcatctaga
     5041 aatacattac aaacaccttc gtgattctca ttcaatcttt ctaaaatcag tggttttaat
     5101 ttatctaaat agccataatt tgtaaaggca atagaaccat ataaattcaa tatcgataag
     5161 acgattactt catcaatccc atacaatgga ttatctttct ccataatctt ttgaaattct
     5221 ggagatagtt tttgtgcttc agctaactta tctaactcaa ttcctgtcat aattacattc
     5281 tgaacttcac gtttttttag tacacgttga attgcatatg aagcgtcgtc aagagttaat
     5341 tcagggtaat atttttgttg tgaaaatatt actaacgctg ccatatcttc aattgtaact
     5401 tcgcgttctt ttagaagttc aatacaatta tcatataaat catatttcat aatcttaccc
     5461 cctcaataga gcattgtctg attcaattct gaaaatatct aaatttcctt cgattgcgta
     5521 gattttagca tttttaaagc taattttcag tcgagtttga gttcgaggta aaggttcgct
     5581 gaataacact tgatagcgac catcttctat tttttcaagg gaagctgtaa tttccattgg
     5641 agtgtgatta ttctcgaaca attcaattgt tacaaagcct ccagctgcaa tatctgcatc
     5701 aaggtaaact tgatcattga ggaaaataaa tccattggta tacaaaacac ctggatattc
     5761 tggacgttta gtatcccaat atgcaaagtg atctttctca atataagcac gagacaagct
     5821 tgtttcacgg aagtttgtat gttgtccatt tcctcccatg tagtagaaat aagtacggtc
     5881 accgatagta actggtgcag aagaatagat acatccacag tcaaattctc catcaccata
     5941 ttgaccttta ccacgaggaa taagtggagt atcagtgttt agataatgcc aaccaacatg
     6001 acgataacta taagtcaatt gaaggtccac tgtatcgtaa ttcttgttca gttgatctcc
     6061 ttcatggaaa actgaagcta aacctagtat ataatcgcca cgtttaaaaa taggcataga
     6121 ataaatttga ttttcataat cacagacatt caaaatttct tgaattggag tccagttaat
     6181 gaaatcagca ctcgtagata cacacggcaa gcgcaatgaa tctctccaag tacgagtaat
     6241 tagcacatag cgatttaatg cttcatcata tatgatatgg ttatgagtgt ctgcacgtgg
     6301 attgaagttt ggtactttaa tgtattcatc aaagtgtaga ccatcttttg aaaatgctac
     6361 agcaatgaaa tgaacaccgt taccgtaatc aatctttgta aacattttat aacgacgatt
     6421 ttcatctgcg tcatgtttat ctagaaaaac agatgtacca tgtaaaaaat gtccgataat
     6481 attattttca gttgatcctc gaaattctgt aatacctaga tttggtttca cccagttaac
     6541 accatcttta ctttcagcat aacaaagtga aacaatacgc ttcgcacgag gtagatattg
     6601 acgttcctta cgctcctcta aagagtattt ttcagactcc tcatcatcag taaatgtaga
     6661 atagtagcaa cgataaacac ctgctaaatc atcaaagaaa acatttggat aactgttatc
     6721 aaaacgaatt tcccatggtt tttcctcagt gaagaaaatt tctttatcct ttactgcctg
     6781 attaactttt aattttacat tactcattcg ataaggatta aaaattcctt tatcaaagaa
     6841 atatattttt ttatttaatt tcatatttac cacctattct ggttttaacg ctacaaaatg
     6901 tgttggtgaa acctgcttaa gatcataagc acgaccatct tcatcataaa attcatggta
     6961 ctgtgcttta aattcaactt cattttcttt acgttttgtt gccaatgcct ctttgaagtg
     7021 ataatcaact tctggaatag cagctaatag ttttttagtg taaatatgca ttgggttatt
     7081 gtagatatct tctcgagaac cagcttctac aatacgtcct ttatgaataa catatagata
     7141 gtcacacatg tatttcacaa cacctaggtc atgagaaata aatacataag tcaaatcttc
     7201 tttattttgg atttcaacaa gataattcaa aacttgcgct tgtacagata gatctaatgc
     7261 tgaaacaggt tcatctaaaa ttaaaatttc tggtttcata caaagggcac gagcaataca
     7321 taaacgttga cgttgtccgc ctgaaaattc atgaggataa cgctccaagt actcaactgg
     7381 cacgtttacc atcttcaagg cttctttcat acgttcaaag cgttcctctt tgtttccaat
     7441 attatggaca atcatcggtt catcaaatga attataaatt ttcttagttg ggttcaatga
     7501 tgcataagga tcttggaata ccatttgaac tttcttacgg aaatccaaat cttccttacg
     7561 tttaattcca taaatatttt gagttttccc attcaaatca atattgattt caccatctgt
     7621 aatatcatgg agtttcatta atgatttcgc aatcgtactc ttaccgcttc cagactctcc
     7681 tacgatacca atagtagttc cttttcttaa ctctagagat acgtcatcaa gtgctttcaa
     7741 cggagaacct agtggcttga atagttgctt cttaggatag tagtactttt taatattttt
     7801 tacttctaaa acaacattac ctacatgttt ttccgctaat gtttcttctt ccttatcttc
     7861 gaaaaagaaa tgtttatagc aagaacacct tacaaaatgt ccgtcaccta aatcatgcaa
     7921 ttgaggttct tcttcatgat gttctttttc taaccatgga atacgatttg cgaatctgca
     7981 tcctttttca gatatttcag aaattgaagg tacgctcccc tggataacat gtagcttttt
     8041 atccatattt tcaggattag gaatagatct taatagagaa cgagtatacg ggtgtttagg
     8101 ttgatcaaag atctgagcta cagttccaac ttcaacgact tcaccagcat acatcactgc
     8161 aacttcatcc gcaatttgag caataacgcc taaatcgtga gtaattaaga taatagaagt
     8221 tccatgctct ttacgtaaat catcaagtaa atcaagtatt tgtgcttgga ttgttacatc
     8281 aagggcagtt gttggttcat ctgcaattag aatatctgga ttacatacca ttgcaatcgc
     8341 tatgactatt ctttgacgct gccctccact aaattggtgt ggatagtcat tcatgcgttc
     8401 tgcagcatta tgaattccaa gtttttctaa catttctata gcacgtttat ttgcctcctc
     8461 tttagaaatg tcataatgtt catgaaggac ttcagtaatt tgattaccaa ttgtatatac
     8521 tggattcaat gcagacattg gatcttggaa aatcattgat atgttttcac cacgtaactt
     8581 tcgaaattct ttaccatatt gctttaattt ttgaagctct atcggcttat cttcatcgaa
     8641 atatgtgatt tcaccttcag caatgcgtcc atttttaggt aataagttta acactgtatt
     8701 cactgttaca ctcttaccgc atccagattc accaacaatc cctaaaactt tccctctttc
     8761 caaagtgaag tttacatctt taataatcgg aaatgctttt ttatcagtga tgaattcagt
     8821 ttttaagttt tttacatcta aaactgtttg attcattttg tcaacctcct actgttgttt
     8881 cggatccatt atatctcgta atccatcacc aataaagttg atagaaagaa cgaaaagagt
     8941 aatgattgac cctggaacta accacaacca ccaactattt ttaataacat cggctgtttt
     9001 ggcagcattt atgatatttc cccaagtagg aatatcagaa ggaacaccta ctcctaagaa
     9061 actaagacct gcctcactga gaatgaaacc agcaacgttt aaagacaacg atacaattac
     9121 tggtgagata gcatttctta aaatattatt aaagataatt cgactgtcag aaaaaccaaa
     9181 agctctacat acatccacat atgtttcttg tttcaaagac atgaactcat tacgaaccat
     9241 tcggaacgtt gtcatccaac ccattactga gaatacgaag ataagattga atacaccttg
     9301 tccaaaaata cttgaaagca agagaatgac aatcatattc gggaatgtta agaataattc
     9361 tgctagacga actagaagag catcaatttt cccaccaaaa tatccagcaa taccaccaag
     9421 tacagtacca ataaccgctc cacaaatcgc tccatacatc ccgacttgaa ttgaaactcg
     9481 accaccatat aggattcgag caaatacgtc acgacctagt ttatctgttc ccagaatgtg
     9541 ttttgctgaa ggaggacggt tcatagatcc taaatcaaca acatctggag aataggttgt
     9601 caataaaggt gctagaatac atgctaatag aattagcatg aagcatataa agccgataaa
     9661 ggccaatttg ttattataga attttttcaa atttcttttc cataaaggca taggtttcat
     9721 aacattgacc tccttcctaa taacgaatac gtgggtctaa tattgcagcc ataatatcta
     9781 caagtagact agcaaataac actacgacag aaatcattaa tgtggtaatc ataattacag
     9841 gatagtcacc tgctgttaca ctagatagga tgatagaacc aattccaggc caagaaaaga
     9901 cactctcgat aattactgat ccaccaatta acattggtag acggaaaatc aataacacta
     9961 aaattggtcg catagcattt ctaaatatgt gtttaaaata aactttccat tcaggaacac
    10021 cttttgcacg agctgtttta acataatctg cattaaaaac atccaacata gaattacgtg
    10081 tgtatctcat taaagcagct accaatgcaa ttgacatagc cattactggt agaattaagt
    10141 gttcaactct attaataaat gtaaaatctc cactggcaaa tctaccacca ataggtaaaa
    10201 ttcttaactg aattgcaaag aagtttaaaa ttaaaatacc aaagaaaaat tgtggaatcg
    10261 cagttccgat aacagctaga aaacgagcaa cattatcgat aataccattt tgtttaacgg
    10321 ctgatataac cccaattaca ataccaacaa ttgttgaaat aattaatgac acaaaagcta
    10381 attcaaaagt tgcaggcaat gcttgtccta caattttgga aattgggtta ccatttacaa
    10441 tactgtatcc aaaatcacca tggagtaatt gccaaagcca tcttccatag cgaactaata
    10501 ctggatcatt taaacctaat tgctgtctta gcttttcgat ttgttctgca ctactagcca
    10561 tatctggaga taccatatat gtcaatggat ctgctggtgt taaatctagt gcaatgaata
    10621 ctaaaaagct aataatcaac aacataggaa tcatgaataa tacttttttt agaatatatt
    10681 ttttcatttt aatttctcct gaaaaaacaa gagtgagaga tacatgattc aataaaccag
    10741 catctctaca ctcctaaaag attatcaaac ttaatcactg ataattttaa acgattttat
    10801 ttagcatccc atttttcgaa tttgtaatca aatttataga atggattacc aaattgaaca
    10861 tcgtcaggaa ttaaaacttt ttcagtattt aaatacaaga agtttttaaa tgtgaataag
    10921 tttaacttca atagtttttc ttgttctaat ttttgtagac ttgctaaaat tttgtttctt
    10981 tcttttacat cagaagtttc agacaatttt ttgctcaact catcaaaact tgtttcgcca
    11041 tttgtaatat ttttaaagtt agtatttgtt gaactatatt caccatacca agtttcataa
    11101 ccaaatgatg ataatccttt ataagctagg tcatatttac gtgttttgaa caatcctgtt
    11161 gttgcatcag aagtaatttg gacaacttcg ttcttgattc caacctcatt caattgataa
    11221 cttactgctt gcatgaaatc ttgagaggct tgatctttat agtaataagc taaaattaga
    11281 tttctgctat tatcgtattt agcttcttta agaagttgtt ttgctttttc tggattatat
    11341 tcaaatttat ttgctgattt cagatgagct tctaagcttg aaggaacacc agtattatta
    11401 acatctgcaa ttccactaaa tacagattta gctaattcat cacgattaat tgcatataga
    11461 atagcttctc taactttagg attagcaatc aaggaatctc cattaccttc gacacctgct
    11521 aagttagcga taaagtagcg atagaatagg atatcaattg gttttttact taaagtagat
    11581 acagcatcca actgactaat ttcttgaggt ttgtttgttg aatagaagta tgatttacca
    11641 tcttgcaatg ctaaaactgg atctgaaata tagttgaata ctactttatc aaattttggt
    11701 ttttcatttt catagttttc atttttgtca tactctaaga aattacctgc actaatttct
    11761 tttactttgt acataccgct tgtaacagga gctgtccaaa atgagctatt atttaattca
    11821 agaggatttt cagactctaa tttatgtttt ggaagaataa agaattgagt catcatttgc
    11881 tcaaagtcac caactggagc agtaagttta aatgttactt tatttccatc aactgtaaga
    11941 ccagaaattt tatctgcttt atcgtctttg aaatctttag ctccttcaat ttttgtgaat
    12001 gttgaaggga aaattccatt aattactgaa gctttcaatg ctaatttaac actgaattcc
    12061 acatcggaag ctgtcaaagc ttctccatca gaccatttca atccatcttt aagtgtaaat
    12121 tcataagttt tttcatcatc agattttttc caatctttag ctaaatctgg agttgatttt
    12181 tcatattttg aatctgccat taacagtgta cggtataaca aatatggaac taaaccatca
    12241 ccattttgcc aaacgtaagg gatacgatct ccagttcctt gaagaaaacc tgataaatag
    12301 aatacttttt cttttccaga ctctgaaaaa tcagattttt tgcttcccga actacaagca
    12361 accaatccta ctacagctat taaaactgct gcagctgtta aagctaattt aacaattttt
    12421 ttcattttaa tactccttta tttgtattaa gtaattattt atgtgattaa gtaagtattg
    12481 cagtaattaa aaatttaaac tcttcgttac atttcctcct ctaacaaaag tatgtcagaa
    12541 gtacgtcttc ctgggctaca ttccccacta acaacgtaat atccattatc agtttttaaa
    12601 aatcctgccc cacaaagagc aaaacgctca tcgtttgcaa taatcttgac cttacctgtc
    12661 tctaaatcta gtattcgcat gctacgattc caattaaaga aatctctccc tttagaaaaa
    12721 tattcttccc tatagccagg ggttgctaaa tcaataactg ctttattata aacaatttca
    12781 ttaaagccac caagtattaa taaaccactt tcatttattt gtatacttga tgctcctaga
    12841 actgagcttg gtaattcgaa ctcaagtttt tcccacttat ctttttttaa actatatttg
    12901 tatccatcta aataagcttc attgttcgct ccacctaaat aatacaattc attttgatat
    12961 ttgactgaca aaccttggcc tctaccagaa actgggaagt cagatttttt aaaaagctct
    13021 tgagtctcaa tattgaacaa ataactttcc tgaaatccaa agaataagtg gccatcaaaa
    13081 taacaaccat aaccactctc tagttggaaa tcaaaattcc cgatacaggt ttcttctaca
    13141 ctttcaccaa tcgtaatacg ataaatgctc gagcctagaa tgtaatagat ttcattttca
    13201 acttcaatcg ttattccttt atctggagaa atttttccat cttgttcata tagaagatta
    13261 aatttctcat cataaactct aattttattt gattgaactt ttgaactttt taaaggatcg
    13321 ttatttggga aataactacc tccataaact aaaattctat tattaatccg tctacaaatc
    13381 atcccagcta atcctggtga gtctaaatga tttataacat caattttcat attacacctc
    13441 ttactctggc atgctatttt aatcccgcta caaaacgttc tgtaatctct tttggtctag
    13501 taatagcgcc accaacaacg atgcctcgca ctccatattc aaggatttgt ttggcttgtt
    13561 ctggtgtat
//
LOCUS       DBEJZJ010000039        13033 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000039 DBEJZJ010000000
VERSION     DBEJZJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.39"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..1000
                     /locus_tag="ACL3R8_001694"
                     /pseudo
     CDS             1..1000
                     /locus_tag="ACL3R8_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1085..2287)
                     /gene="rpsA"
                     /locus_tag="ACL3R8_001695"
     CDS             complement(1085..2287)
                     /gene="rpsA"
                     /locus_tag="ACL3R8_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR1314537.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2449..2520)
                     /locus_tag="ACL3R8_001696"
     tRNA            complement(2449..2520)
                     /locus_tag="ACL3R8_001696"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2486..2488),aa:Gln,seq:ttg)
     gene            complement(2530..2610)
                     /locus_tag="ACL3R8_001697"
     tRNA            complement(2530..2610)
                     /locus_tag="ACL3R8_001697"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2574..2576),aa:Tyr,seq:gta)
     gene            complement(2660..2890)
                     /locus_tag="ACL3R8_001698"
     CDS             complement(2660..2890)
                     /locus_tag="ACL3R8_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR1314538.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3058..3702)
                     /gene="pcp"
                     /locus_tag="ACL3R8_001699"
     CDS             complement(3058..3702)
                     /gene="pcp"
                     /locus_tag="ACL3R8_001699"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR1314539.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3717..4640)
                     /locus_tag="ACL3R8_001700"
     CDS             complement(3717..4640)
                     /locus_tag="ACL3R8_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR1314540.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4637..5326)
                     /locus_tag="ACL3R8_001701"
     CDS             complement(4637..5326)
                     /locus_tag="ACL3R8_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR1314541.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5391..6095)
                     /locus_tag="ACL3R8_001702"
     CDS             complement(5391..6095)
                     /locus_tag="ACL3R8_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR1314542.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6151..7173)
                     /locus_tag="ACL3R8_001703"
     CDS             complement(6151..7173)
                     /locus_tag="ACL3R8_001703"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR1314543.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7305..9776)
                     /gene="parC"
                     /locus_tag="ACL3R8_001704"
     CDS             complement(7305..9776)
                     /gene="parC"
                     /locus_tag="ACL3R8_001704"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR1314544.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9977..10181)
                     /locus_tag="ACL3R8_001705"
                     /pseudo
     CDS             complement(9977..10181)
                     /locus_tag="ACL3R8_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(10196..12139)
                     /gene="parE"
                     /locus_tag="ACL3R8_001706"
     CDS             complement(10196..12139)
                     /gene="parE"
                     /locus_tag="ACL3R8_001706"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR1314545.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12275..12916
                     /gene="plsY"
                     /locus_tag="ACL3R8_001707"
     CDS             12275..12916
                     /gene="plsY"
                     /locus_tag="ACL3R8_001707"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR1314546.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12959..>13033)
                     /locus_tag="ACL3R8_001708"
     CDS             complement(12959..>13033)
                     /locus_tag="ACL3R8_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR1314547.1"
                     /translation="YNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3761 a         2949 c         2294 g         4029 t
ORIGIN      
        1 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
       61 tcaacttcaa ctgtcattcg caagctcaat gattctcact ttgagcatga tttttcgcgt
      121 cttcctgaga ttatgtcctg ggacgttgaa acagtccggg gagtgactgt ttcaatcggg
      181 agatggagat gagcttcatt gcgcaagatt ttaacaatct caatatcatc actgttcttg
      241 agggaagaac acaagctatc attcgaaatc actttcttcg ctacgataga gctgtccgat
      301 gtcgcgtcaa aattattact atggatatgt ttagccctta ctatgacttg gctaaacagc
      361 ttcgctttca aatttctagg ctcaggctga aacagtctcc cagactgttt cactcccgaa
      421 tgctaaaatc gttcttgatc gctttcacat tgtgcaacat cttagccgtg ctatgagtcg
      481 tgtgcgtgtt caaaacatga atcagtttca tcgaaaatcc catgaataca aggctatcaa
      541 gcgctactgg aagctcatac aacaggatag ccgtaaactg agtgataagc gattttatcg
      601 tcctactttt cgtatgcatt taaccaataa agagatttta gacaagcttt tgagctattc
      661 acaagacttg aaacaccact atcagctcta tcagctcttg ctgtttcact tccagaataa
      721 ggaaccagag aaatttttcg gacttattga ggacaatctt aagcagtctc atcctatttt
      781 tcagactgtc tttaaaacct tcctcaaaga taaagaaaag attatcaacg cccttcaact
      841 acactattct aatgccaaac tggaagcgac caataatctc atcaaactta tcaagcgcaa
      901 tgcctttggt tttcgaaact ttgaaaactt caaaaaacgg atttttatcg ctttgaacat
      961 caaaaaagaa aggacgaaat ttgtcctttc tcaagcttag ctgacttcaa cccactacag
     1021 ttgacaaaga gccagaaaaa tcccttgttt agtaaacaaa ggattttgtg aattttcaat
     1081 ttgattaaag ttcgatatca ccaaacaaat cagccattga aaatcctgtt tgtgtttctg
     1141 gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg tggacgagca gcacgttttt
     1201 cttctttttg tccttcttct tgggctggac gttcttcaag agctttaata gaaagtgaca
     1261 cgcgttctgc atctgcgtta acttcaagaa ctttaacttg aacttcttga ccaactttaa
     1321 gagcttcttt tggattttca atccgtttgt gtgaaatttg tgatacgtga acaagtccat
     1381 cgatacctgg caatacttca acaaatgcac cgaagtcagt caaacgttta actgttcctt
     1441 ctactacatc acctttagcc aatttttgct caacgccatc ccatggtcct ggtactgttg
     1501 ctttaagtga aagtgataca cgtccttctt cttcgttaag atcaaggatt ttcacttcaa
     1561 tttcttcacc aacagttaca actgattttg gtgatacgtt acgttcatgt gacaattcag
     1621 tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa agcgccgaag cttgtgatac
     1681 gagcaacttt accagttaca acatcaccaa cagccaattt accgaatact tcagcgcgag
     1741 ctgctgcagt agctgcttca acaacttcac gacgtgaaag gatgaagcgg ttttctttag
     1801 cgttaacttc tttgatttta gtatcaaatt cttgacctac aaaacgctca gcgttacgta
     1861 cgaaacgagt atccaacatt gaagctggga taaatccacg aacaccttca aattctactg
     1921 aaagtccacc tttaacggca cgcgttcctt taacagtaac aacttcttct tcgcgaccaa
     1981 caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt agatacaagg tatgtaactg
     2041 tatcagtatc tttaccaact acttgacgaa gtacaagaac atccaatact tctcctactt
     2101 taacaaagtc attgatatct gcatcacgat cgtttgtcaa ttcgcgaaga gtcaagacac
     2161 cttcaacacc agttccagag attgcaacgt tagcttgagt cgcatcaact gtcaatactt
     2221 cagcactaac aacatcacca gtctcaactt gactaacgct atttagcaaa tcttcaaatt
     2281 cgttcatcta aaaaatcctc caacaatcaa gtttttctta aacttgacat acttataatt
     2341 tttttcctaa gcacccgcaa ggacatgttc atatcattca cgtctttcaa ttataaaaat
     2401 aaaataccct aagatatttt gctttctatc ttgattatta cctaagaact ggggtagctg
     2461 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     2521 ttaatgaaat ggagagagag ggattcgaac ccccgaaccc gaaggagcgg atttacagtc
     2581 cgccgcgttt agcctcttcg ctatctctcc tacaatcaac atggactatt atatcatgaa
     2641 aatttcaaaa aaacaagact tattttgcta aattataatt ttcaatcaaa atttccacag
     2701 ctttttccaa ttttttataa aaactatcga cattcccatt ctttataatg gcaaattgtc
     2761 cgtctaattc ggcaatttct ccgataactt ttttaccgat agtcaatgta taaccttcaa
     2821 aactgtcttt accaacatta actttggcat ccgctacttg aatttcgatt tttttatctt
     2881 tcttgctcat ttcatacctc tcttcacttt ttctatttta caagaaaatc ctaaaactag
     2941 caagaaaaaa ctctatatca ggcttctctg atatagagtt ttatgtaaac aacctcaatt
     3001 gatttagcat agttaatagt tagtaaacaa gcataattga ctatcctttt taggttatca
     3061 gtgagtctca ccgcctacta actgcaaatc cttatctttg tagtctacaa tagcttcaat
     3121 agctacctct atgcctctta caatatcaca tagactcatt cctgcagtat tcggcttatt
     3181 tactacttgt tccatcatat atggaatatg catgaaacct gctctcatat tagggaattt
     3241 tttatccact aaataaagag cttggtacat caaatgattg caaacaaagg ttcctgcact
     3301 attggataca actgccggaa gtccctgttt tttgatagct tgtaccatcg ctttgatagg
     3361 taaactacta aaataggccg atgctccatc aatacgaatc ggtgtatcaa ttggttgatt
     3421 gccttcgtta tcaggtatgc gagcatcatc ttgattaata gccactcgtt caggtgttaa
     3481 gccggtcctg ccgcctgctt gtccaataca aagtacagca tctggttgat atcgtaatat
     3541 ttctgcctct aaaacttctg acgacttata aaaaaccgtt ggaatttcta cccagcgaac
     3601 ttcagcccca ttaatctcag atggtaataa ttttacagcc tccaaagctg gattaatctt
     3661 ttcacctcca aaaggattaa aacctgtaac caatattttc attttatttt cctttactaa
     3721 aatgcgagaa agtacattaa gaatatgtga ataacaatca ttactagagc aacacctgct
     3781 tgagccttta taacgccatt ctgatctttc atatccatca atgctgctgg tagagcgtta
     3841 aaattagcag ccattggggt caataaggtc ccacaataac ctgctgtcat ggcaagagca
     3901 ccagccacaa ttggattagc tcccagagca aatacaaagg gaactccaac acctgctgta
     3961 ataacggtga atgctgcaaa agcatttccc ataatcattg tgaatagaac cattccaaga
     4021 acataagcca aaactcctat aaagcgacta tctgaaggaa caataccgct aatcagatga
     4081 gagataacat caccaacacc tgctacagta aaaatagccc ccaaagcccc taataattga
     4141 ggaacaatcc cacttgttga aacttgctga gtcattcgat tattttctga taacagactc
     4201 ttagggtgac tattggtaat cacaagaaca gaaattgtag caaacaaggc ggcaaggcta
     4261 atcgaaatct tgctaaattc tggaatcatt tgcgctaaga ccaacgcaag tattgccatc
     4321 agcataactg gaataaaaat tttatttttc aacctgttag attcaatatt ggctttcatt
     4381 tcatctaagg atggcaaggt tccgatacgg acttgcttaa acaatgttaa cagcgataat
     4441 aggattacaa taataccaat actcatattt ggcatatagg aaccacctat aaacgtaata
     4501 gacaatagag tccaaaatgc agatgtccca agtcgaactg ggtttgtttt atctttataa
     4561 ctacaatagg ctgtatggag aaattgacaa ccaatcacaa tataggtcaa ctctaatagt
     4621 tgctttgcca actctgtcat ttttgttctc ctcccctagt cttttttgat atcaattttt
     4681 tatcaaataa ataattgtaa atccccacta caataagtgt tataacagca acaataatag
     4741 atgtagaagc aatccctgca taattgcttt catagcctaa ctgatctaat gttcccccta
     4801 tcaagaggac tcccccagca cctacaaacg tattttgagc aaagaaattt ccaaaatttt
     4861 cattcgcagc cgcacgcgct tttattgtct catcttcaac ctctgttaac tttctaccta
     4921 attgagactc tgcagctgct tctcccatag gttgaaccaa aggtctgaca aactgagggt
     4981 gtcctcctag acgaattgaa aagaaaccag ctaactctcg aataaagaaa taaactgtat
     5041 agaagtttcc aactgtcaga cctttaatct ttcgaatcaa atcgattgat cgttgcttga
     5101 gtccaaaggt ttctgacagc cccacaagag gcaaggtaac cataaaaatc gtgagcactc
     5161 gctgattgct aaattctttt cccaaaatct ccaaaaattc aacgagagaa acacctgaaa
     5221 ctaaagctgt aaccaaacca gctaagacta ctgttgcaat tgtatcaaat tttaaaataa
     5281 aacccacaac aatgattgct attcctatta atctaatcca ctccatatca aactccttta
     5341 tattcaaaat gacagtattt taaaaatttt atcaagatca ataccattcc ttatttaatg
     5401 tatttttcta gttctttttg gtatttgcta ttggattcca atttttcttt ttgccatttt
     5461 ttaaaaacct cgttatattc ttttgttgta acaatatctt tttgcaattt cattccttta
     5521 aagatatatg gttccccctt aataccaact tgtgagtatg gttttgagaa tggtactacg
     5581 ttacttacaa ctggagaacc accagatgaa gctgttggca tcaataatga actatctgtc
     5641 gaccaagctt gagctttggc atatttttca tatctcttct ctaggtcagt ggtctcagaa
     5701 acagcatctt ctaacaattt cttatattta tccaaaccag gtttagctac aacatcctta
     5761 tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac cagattttgg atccataata
     5821 ttcaagtaag acgctggatc ttgatagctt ggagcccatc ctgtactatt caaatcatag
     5881 tctttttgag aaggagcaac attgccgtat ttatcatttt ccatcaaacc atcaataaca
     5941 tttccaataa cgtctgtcgt cgatgttcga gtcgctatac tgtagcccaa tgatgctgga
     6001 tctactgcat agacataaga aaatgttgtc ggtgcatctg cttctttatc agtttttcca
     6061 caagccacta aaatagctga cgtgctcagg accactcctg ctgttaagag ccgctttttc
     6121 tatttcataa aaaatctcct ttggtttatt ttaatctact tttacaatcc aaccttctgg
     6181 cgcttcaata tcgccaaact gaatacccgt caattcatta tataatttac gcgtcacagg
     6241 acctacttct gtttcactat agaatacatg gaaatcatca ccatgttgaa tacctccaat
     6301 tggagaaata accgctgctg taccacaggc acctgcctct acaaaacggt caagattatc
     6361 aattggaaca tcaccctcaa taggagttaa tcccaagcga tgttctgcca aataaagcaa
     6421 ggaatacttg gtaatagatg gcaagataga tggactcaat ggtgttacaa attcattatc
     6481 agctgtaatt ccaaagaagt tagctgatcc gacttcttca atctttgtat gagttgatgg
     6541 gtccagatag ataacatctg agaaatgacg tgacttggcc atttttcctg gtaagagact
     6601 tgcagcatag tttccaccaa ccttagccgc acctgtacca tttggtgctg cacggtcgta
     6661 ctcatcctga atcaagaagt tggttgggac caaaccacct ttaaagtaat ttccaactgg
     6721 catagcaaag atggtgaaaa tgtattcttc tgccggtttt accccgataa tatctccgac
     6781 accaatcaaa agagggcgaa gatataaggt tccacctatt ccgtatggtg gtacgtattc
     6841 ttcattcgca cggacaactg ctttacaagc ttctacaaac atgtctgtcg gaacttgtgg
     6901 catcaagaga cggtcacatg tacgttgcag gcgtttagca ttttcatcag gacggaacag
     6961 ttgaacactg ccatccttag tacgataagc tttcaaacct tcaaatgctt gttgtccata
     7021 gtgaagactt ggagaagact ctgaaatatg caaagttgca tcctctgtaa gctctccttg
     7081 atcccattgt ccatttttga aatgagcaag atagcgataa ggtaatttca tataggaaaa
     7141 accgaggttt tcccaatcaa tcgttactgt catattccac tccttattct aaaaacctat
     7201 ttcttatatt ctacactatt tttctaaaat agcaagtata ttttgtaatt ttcagaaaat
     7261 ttctccaata aaaaccagct cttagaactg attcttcatt tcacttattt atcttcagta
     7321 actacttcct gaagataagc gtcaaaaact tcttcatctg aaatcgtgtc agaaatgaag
     7381 cttccattgc tagtgcgttc tgacaagttc aagtcttgca atcggctttc atagattgtt
     7441 cctttattgg attggacaag cagagtttgg tcgttcacat ccacttccgt actgaagaaa
     7501 tcgccaacaa atccttgctc tgcaactgct cctgccaaga agacacgatg cggtttgttt
     7561 ttcaactcac gcaagacttg taatcctcgt ttggcacggc tggttgctag aatttcctca
     7621 atggaaacac gtttcaagct tccacgctgg gtcaagaggt agaaggacga agtattacag
     7681 ataaagccag attggaggac atcatcttct ttcaaattca tagccttgac acctgctgcc
     7741 ttagcaccga caaccggaac ctcttcgata ttgaaacgca gggcataacc attttgacta
     7801 accaagacaa catcatctag tttaatcgga gccactgcta caatctgatc tgtatcgtct
     7861 ttgagcttag catacttgac agacttagat ctataggtcc gccatggagt gaattctttt
     7921 cgctctaccc gtttgatttg accaaggcga gtcgctgcaa agtaggttgt cgcatcgtca
     7981 aactgatcca gtacttccac ataaaggatt gcttcattcg tttcaaagtt tgtgatggtt
     8041 tggctcagat gctctccgat gtccttccaa cgaatatctg ccaactcatg gattggtctg
     8101 tagatgacat ttccaagact tgtgaacatc aagaggtgct gggttgtctt ggcagattga
     8161 acaaaaatca aacggtcatc atcacgcttg ccaatttctt ccaaggtgga agccgcaaag
     8221 gaacgtggac tggtacgctt gatgtaacct gccttggtca cgctgacgta ggtatcttcc
     8281 tcagcgataa gactagctgt atcaatctca attgctttcg cagtgtcttc taaagaactc
     8341 aaacgaggag ttgcaaattt cttcttgacc tcacgaagtt ctttcttcat gagattgtac
     8401 atagtccttt catcaccgat aatagccacc agcatagcaa tcttctcacg aagctctgct
     8461 tcttcttcct gcaagacaac cacatcggta ttggtcaaac ggtacagttg caaagttacg
     8521 atagcctcag cctgttcttc cgtaaaatca tagctaactt tgaggttttc cttggcgtcc
     8581 gccttattct cagaagcacg gataagagca atgacttcat ccaaaatcga aatcacacga
     8641 atcaaacctt cgacgatatg gagacgtttc tcagcctttt ctttgtcaaa gcgtgaacgc
     8701 gccaaaatca cttctcgacg gtgagcgatg tagctagaca ggattggaac aatcccaacc
     8761 tgacgaggtg tgaaattgtc aatcgccacc atattaaagt tgtagttgat ttgtaggtcg
     8821 gtgtacttaa ataagtagtt gagaacaagc tcagtattag cgtctttctt aagttcgata
     8881 gcgatacgaa gaccatcacg gtcagactca tcacgaacct cagcaatccc agctaccttg
     8941 ttattaacac gaacatcatc gattttcttg actagattgg ccttattgat ttcataagga
     9001 atctcagtaa taacgatttg ttccttacca ccttttagct tttcaatttc agtcttggaa
     9061 cgaacaacca cgcgcccttt cccagtctca taagctttct tgatttcatc acgaccctga
     9121 ataatagccc ctgtagggaa gtctggtcca ggcaagaatt ccatgagttt atcaatcttt
     9181 gcagttgggt ggtcaatcat gtaaactgca gcatctatga cctcagctaa attatgggga
     9241 ggaatgtctg tggcataacc agccgaaatc ccagtcgaac cattgaccaa gaggtttgga
     9301 aaggctgctg gcaagaccgt tggttctttc tccgtatcgt caaagttcca tgcaaaagga
     9361 actgtctttt tctcgatatc ctgaagaagg tagcctgcaa tttcagacaa acgtgcctca
     9421 gtataacgca tagccgcagg aggatctccg tccatagaac cgttattacc gtgcatttca
     9481 actagaatct cacgattttt ccagttctgt gacatacgaa ccatggcgtc atagatagaa
     9541 gaatccccgt gtgggtggaa attccccatg atgttcccga ctgacttggc cgacttacgg
     9601 tagctcttgt caaaagtatt gctatcctta ttcatagaat aaagaatacg gcgctgaacc
     9661 ggcttcaacc catcacgaat atctggcaaa gcccggtctt gaataatgta cttggagtag
     9721 cgaccaaagc gctctcccat gatgtcctcc agggacatgt tttgaatgtt agacataaga
     9781 tacaaagccc ataaaatacc aagtgaaaat agaaaattct tgaagtaagc aaactcacaa
     9841 gagaatttat ctttttcaca cagtatctag ggcgtgttca actcctttca aagaatgtag
     9901 agtaggtttt tatgcagtaa aagatatttt acgggaattc gtcccgtgtt cagttacgat
     9961 aagtaaccaa actatcctgt ttgtattttt caatatgaaa atatggtttt ccaaaattag
    10021 tcttagtttg tgtcttagcc gctcccttaa acgcctcttt gagataagca ctcatagcag
    10081 attcttcatt aataatcctg caattttttc aaaccaagat tttcaaactg ctttttcaca
    10141 tagtcattca catccgactc taatttccag tttactaaca tattattttc tttcattaaa
    10201 acactgtcgc ttcttctagc gtaaacttga cattatcttc aatccattta cggcgtggtt
    10261 ctaccttatc tcccatgaga acattgacgc ggcgttcggc gcgcgctaaa tcttcaattg
    10321 tgacacggat gagggtacgt gtttctgggt tcatggttgt ttcccagagc tggtccgcat
    10381 tcatctcacc aagtcctttg tatcgttgga gggtagcgcc tttaccgaac tgtttacgga
    10441 gttcttctag ttctccgtcc gtccaagcgt aggccacttc ttctttcttg cctttacctt
    10501 tggacatctt gtaaagaggt gggagggcaa tatagacatg acctgcctcg actagcggac
    10561 gcatgtaacg gtagaaaaat gtcaagagca aggtctggat atgggcaccg tcggtatccg
    10621 catcggtcat gataatgatc ttatcatagt tggcatcttc aatagagaag tctgctccaa
    10681 cacccgcacc aatggtataa atcatggtat tgatctcttc atttttgagg atatccgcca
    10741 tcttggcctt ggctgtattg acaaccttac cacgaagagg tagaatagcc tggaacttgc
    10801 ggtcacgacc ttgtttggca gaaccaccgg cagagtcccc ctcaactaga tagagttcat
    10861 tcttagcagg attcttagat tgggctgggg tcaatttccc agacaacaag cccttatctt
    10921 tcttgttttt cttcccattt cggctctcat cacgcgcctt acgtgctgct tcacgagcat
    10981 cacgggcctt gatagccttg cggatgaggt tagaagctaa ttccccattt tccataagga
    11041 aaaaggtcaa cttatcagcc actattccat ccacaactgg gcgagctagg gggcttccta
    11101 gtttatcctt ggtctgtcct tcaaactgca agtgttcttc aggaactaag atagaaagaa
    11161 cggccgctag tccctcacga tagtctgaac cttcaaggtt tttatctttt tccttgagaa
    11221 gacctgtttt acgtgcatag tcattcatga ccttggtaat ggcagacttg agtcctgtct
    11281 cgtgcgttcc accgtccttg gtgcgaacgt tattgacaaa ggatagaatg ttatctgaga
    11341 atccgtcatt gtactggagg gctacttcca cttgaaaacc attgtcttcc ccttcaaagt
    11401 aaagaactgg cgtcaagatt tccttatctt cgttgagata agaaacaaaa tcttgtactc
    11461 cattctcata gtggaactca atcgcttcat ctgttcgctt gtccgttaaa gacaaggtca
    11521 catttttcaa gagaaaggct gattcattaa ggcgctctga aatggtattg tacttgaaat
    11581 ctgtcgtaga aaagatagtc gcgtcaggca taaaagtaac tttggtgcct gttttagact
    11641 tgggtgctgt accgattttc ttcaaagtcg tgacaggttt tccaccattt tcaaaacgtt
    11701 gcttgtaaac tgcgccatca cgggtaattt caacttctaa ccagctagaa agggcgttaa
    11761 caacggaaga acccactccg tgaagtccac ctgatgtctt atagccacct tgaccgaatt
    11821 tccctccggc atgaagaatg gtaaagataa cctcaacagt tggaattccc atagcgtgca
    11881 tacctgtcgg catcccacgt ccatggtctt gaaccgttag actaccgtct ttattgatag
    11941 ttacatcaat acgatcacca aacccagaca aggcttcatc gactgcatta tcaacgattt
    12001 cccaaactag gtgatgaaga ccagcgccat cggtcgatcc aatatacatc cctggacgtt
    12061 ttcggaccgc atccaaccct tctagcacct gaatagcatc atcattataa ttgttaatat
    12121 tgatttcctt ttttgacaca aggaacctcc tattcgttca tctttactat tctacaggtt
    12181 ttccaaggat tttgcaaaat ttttctttct ccgatgtgac aatttcagca gagattctct
    12241 gcttttcttt cccaattcat gatataatag gagtatgatt acaatagttt tattaatcct
    12301 agcctatctg ctgggttcga ttccatctgg tctctggatt ggacaagtat tctttcaaat
    12361 caatctacgc gagcatggtt ctggtaacac tggaacgacc aacaccttcc gcattttagg
    12421 taagaaagct ggtatggcaa cctttgtgat tgactttttc aaaggaaccc tagcaacgct
    12481 gcttccgatt atttttcatc tacaaggcgt ttctcctctc atctttggac ttttggctgt
    12541 tatcggccat accttcccta tatttgcagg atttaaaggt ggtaaggctg tcgcaaccag
    12601 tgctggagtg attttcggat ttgcgcctat cttctgtctc taccttgcga ttatcttctt
    12661 tggagctctc tatcttggca gtatgatttc actgtctagt gtcacagcat cgatcgcggc
    12721 tgttatcggg gttctgctct ttccactttt tggttttatc ctgagtaact atgactctct
    12781 cttcatcgct attatcttag cacttgctag tttgattatc attcgtcata aggacaatat
    12841 agctcgtatc aaaaataaaa ctgaaaattt ggtcccttgg ggattgaacc taacccatca
    12901 agatcctaaa aaataaaacg ccagttctgt actgacccca aaaagttaga caattaattt
    12961 atccgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt accttaattc
    13021 gtttattgtt gta
//
LOCUS       DBEJZJ010000040        12946 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000040 DBEJZJ010000000
VERSION     DBEJZJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.40"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            180..1346
                     /locus_tag="ACL3R8_001709"
     CDS             180..1346
                     /locus_tag="ACL3R8_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR1314548.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            1462..2499
                     /locus_tag="ACL3R8_001710"
     CDS             1462..2499
                     /locus_tag="ACL3R8_001710"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR1314549.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            2616..3829
                     /locus_tag="ACL3R8_001711"
                     /pseudo
     CDS             2616..3829
                     /locus_tag="ACL3R8_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
     gene            4281..9851
                     /gene="zmpC"
                     /locus_tag="ACL3R8_001712"
     CDS             4281..9851
                     /gene="zmpC"
                     /locus_tag="ACL3R8_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HGR1314550.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            10207..11061
                     /locus_tag="ACL3R8_001713"
     CDS             10207..11061
                     /locus_tag="ACL3R8_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR1314551.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            11167..11724
                     /locus_tag="ACL3R8_001714"
     CDS             11167..11724
                     /locus_tag="ACL3R8_001714"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HGR1314552.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            11941..12705
                     /locus_tag="ACL3R8_001715"
     CDS             11941..12705
                     /locus_tag="ACL3R8_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR1314553.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
BASE COUNT         4210 a         2203 c         2906 g         3627 t
ORIGIN      
        1 ttatccggca acctcaaagc agtgctttga gcagcctgcg gctagtttcc tacagatttt
       61 agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat tttatataga
      121 atatacatgg gaatgtagct tactcccatt cccatattta atagaaaaag aggaactcaa
      181 tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact acgcgtgaaa
      241 tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca aaacgtgaag
      301 aaattgcagc cttcctacaa gaaatcgctg ataaacatga ctatattaag gttatcttga
      361 caggtgctgg gacttctgct tatgtgggag ataccttgct accttatttt aaggaagtct
      421 atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt gccaatccag
      481 caacctattt gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt agtgggaatt
      541 cgcctgaaag tttggcgact gttgatttgg ccaaatcctt ggtggatgag ctttatcaag
      601 tgacgattac ttgtgcagca gatggtaaat tggctcttca agctcacggt gatgatcgta
      661 atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg acttctagct
      721 ttacgtctat gatgttgaca actctcttgg tctttgatcc tacagaattt gctgttaagt
      781 ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag gcagaagatg
      841 tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct ggtcctttct
      901 ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt caagttgcga
      961 ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc aacgacaata
     1021 cagttgtttt ggtctttggt acaacgacag actacactcg taagtacgac ttggacttgg
     1081 ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt gatcaagctt
     1141 ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg aatgatattt
     1201 accgtgtctt cccttacatc gtttatgccc aactctttgc tttattgact tcactcaagg
     1261 tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta gtacaaggtg
     1321 tcataattca cgaatatcaa aagtaagaca gtgtttatga attcttgaca agaggatttg
     1381 taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt tgcttgagag
     1441 aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg aaatgttgag
     1501 ggtgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact tgaggttatg
     1561 acttatggtg cgactatctt gcgctatgtc gcacctgaca aggctggaaa ttttgccaat
     1621 gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa gcatggagca
     1681 agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa tggtaagacc
     1741 tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac tggttgggat
     1801 tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta cacagagcgt
     1861 acagatggga caggagggtt ccctggaaat ctcaagattt ggatcagtta tcacttggaa
     1921 gaaactggtg cctatgaaat cagctacaag gtaacgaccg atcaggatac gctggtcaat
     1981 ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat tgaccgtcat
     2041 gtcttccaac taaacacaga gggcatttac tcaatcgctc ctgacggtgt tcctgccaaa
     2101 actccagaag ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt gttgaaggat
     2161 atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca tccatttgcc
     2221 cttcctgcag gccatgacaa tgctggattc ctttatgacc aaaattcagg tcgcttcctg
     2281 cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt ggatgaaagt
     2341 gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga agcgcaagct
     2401 ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc tggtcaaacc
     2461 ttcaccagta agacacgtta tgaacttgtt gtgaagtaaa agagtcattg cgcctacttt
     2521 tgggagctag gaataggtac gcagagacaa atagtaggaa aatatgatat aactaagcgt
     2581 tgaaagctat ctgttaatat aatattcaaa ctacaataag gagtaagaaa gaaacgaaga
     2641 aaattgtatt tgctagtgcc ttggctttga ccttggctgg agcagttttg acaaatgatg
     2701 tttttgcgaa cgacagactt gtggcaacac aaactactga tggtaaaaat gaaaatgtat
     2761 tgacctcaga ggtgctaaaa ccttctagtg gcaatgtttt ggttggaatc aaaggagaat
     2821 ttgtggctcc tcatcaacaa tctattttgg atgccatcaa tgctatctgt aaagaagcgg
     2881 ctgacgaagg tttggtagat aagtatgtcc ctatcaaatg gtcaactgac ctagaaaagg
     2941 cagcttttgc cagagctaca gaagcatcta taaccatgga tcatacccgt ctttctagca
     3001 aagatctttg gagtgccttt ccaacttcta atagtataat gggagaaaat ttggcatgga
     3061 atcatgacgg ttttctaaaa gctattgaac aatggcgtgc tgaaaaagca gattatgtgg
     3121 agaaaaaaat agtggttcag acaacgggaa atctggtcac tatgagtcgc taattaaccc
     3181 taaatttaca cacatgggga tggcagcttt taaaaatcct aacaatcaat acaaagctat
     3241 tacaattgct caaactctag gtgatgatgc ttcttcagag gaattggctg gtagatatgg
     3301 ttctgctgtt cagtgtacag aagtgactgc ctcaaacctt tcaacagtta aaactaaagc
     3361 tacggttgta gaaaaaccac tgaaagattt tagagcgtct acgtctgatc agtctggttg
     3421 ggtggaatct aatggtaaat ggtatttcta tgagtctggt gatgtgaaga caggttgggt
     3481 gaaaacagat ggtaaatggt actatttgaa tgacttaggt gtcatgcaga ctggatttgt
     3541 aaaattttct ggtagctggt attacttgag caattcaggt gctatgttta caggctgggg
     3601 aacagatggt agcagatggt tctactttga cggctcagga gctatgaaga caggctggta
     3661 caaggaaaat ggcacttggt attaccttga cgaagcaggt atcatgaaga caggttggtt
     3721 taaagtcgga ccacactggt actatgccta cggttcagga gctttggctg tgagcacaac
     3781 aacaccagat ggttaccgtg taaatggtaa tggtgaatgg gtaaactagg ctcaggccat
     3841 aggtaaagca ttcatcttac ttagcaaaaa gaatgaacga taagaaagag gttgatggcg
     3901 aacattggcc tcttttgatt tataaagatt ggattcttgt cgcctcaatt tcagactttt
     3961 ctattgtaag ctaatatttt atagcccatt aaaagcataa gcggtaatct aatttaaaaa
     4021 atgctgtaat tagtctgaag tccacactta cttgttgaga tgttatctct gttttttatc
     4081 gttataattt actgtatttt ttatagtatg cagaatattt ttaagtatat ttcaatagaa
     4141 atttctatcg atttattgta taatgataag taattgttga aaagtactca gaaaattcca
     4201 tactatatta tttttatgtt tatactttta tgctataaaa tatagattga tataaagaat
     4261 atagaaaaag cgaggttaat atgagccgaa aaagcattgg tgagaaacgc catagtttct
     4321 cgatgagaaa gttgtcagtg ggattggtat cagttactgt atctagtttc tttttgatga
     4381 gtcaagggat tcaatcggta tcggccgata atatggaaag tccaattcat tataagtata
     4441 tgaccgaggg taaattgaca gacgaggaaa aatccttgct ggtagaggcc cttccacaac
     4501 tggctgaaga atcagatgat acttattact tggtttatag atctcaacag tttttaccga
     4561 atacaggttt taacccaact gttggtactt tcctttttac tgcaggattg agcttgttag
     4621 ttttattggt ttctaaaagg gaaaatggaa agaaacgact tgttcatttt ctgctgttga
     4681 ctagcatggg agttcaattg ttgccggcca gtgcttttgg gttgaccagc cagattttat
     4741 ctgcctataa tagtcagctt tctatcggag tcggggaaca tttaccagag cctctgaaaa
     4801 tcgaaggtta tcaatatatt ggttatatca aaactaagaa acaggataat acagagcttt
     4861 caaggacagt tgatgggaaa tactctgctc aaagagatag tcaaccaaac tctacaaaaa
     4921 catcagatgt agttcattca gctgatttag aatggaacca aggacagggg aaggttagtt
     4981 tacaaggtga agcatcaggg gatgatggac tttcagaaaa atcttctata gcagcagaca
     5041 atctatcttc taatgattca ttcgcaagtc aagttgagca gaatccggat cacaaaggag
     5101 aatctgtagt tcgaccaaca gtgccagaac aaggaaatcc tgtgtctgct acaacggtgc
     5161 agagtgcgga agaggaagta ttggcgacga caaatgatcg accagagtat aaacttccat
     5221 tggaaaccaa aggcacgcaa gaacccggtc atgagggtga agccgcagtc cgtgaagact
     5281 taccagtcta cactaagcca ctagaaacca aaggtacaca aggacccgga catgaaggtg
     5341 aagctgcagt tcgcgaggaa gaaccagctt acacagaacc gttagcaacg aaaggcacgc
     5401 aagagccagg tcatgagggc aaagctacag tccgcgaaga gactctagag tacacggaac
     5461 cggtagcgac aaaaggcaca caagaacccg aacatgaggg cgaagcggca gtagaagaag
     5521 aacttccggc tttagaggtc actacacgaa atagaacgga aatccagaat attccttata
     5581 caacagaaga aattcaggat ccaacacttc tgaaaaatcg tcgtaagatt gaacgacaag
     5641 ggcaagcagg gacacgtaca attcaatatg aagactacat cgtaaatggt aatgtcgtag
     5701 aaactaaaga agtgtcacga actgaagtag ctccggtcaa cgaagtcgtt aaagtaggaa
     5761 cacttgtgaa agttaaacct acagtagaaa ttacaaactt aacaaaagtt gagaacaaaa
     5821 aatctataac tgtaagttat aacttaatag acactacctc agcatatgtt tctgcaaaaa
     5881 cgcaagtttt ccatggagac aagctagtta aagaggtgga tatagaaaat cctgccaaag
     5941 agcaagtaat atcaggttta gattactaca caccgtatac agttaaaaca cacctaactt
     6001 ataatttggg tgaaaataat gaggaaaata ctgaaacatc aactcaagat ttccaattag
     6061 agtataagaa aatagagatt aaagatattg attcagtaga attatacggt aaagaaaatg
     6121 atcgttatcg tagatattta agtctaagtg aagcgccgac tgatacggct aaatactttg
     6181 taaaagtgaa atcagatcgc ttcaaagaaa tgtacctacc tgtaaaatct attacagaaa
     6241 atacggatgg aacgtataaa gtgacggtag ccgttgatca acttgtcgaa gaaggtacag
     6301 acggttacaa agatgattac acatttactg tagctaaatc taaagcagag caaccaggag
     6361 tttacacatc ctttaaacag ctggtaacag ccatgcaaag caatctgtct ggtgtctata
     6421 cattggcttc agatatgacc gcagatgagg tgagcttagg cgataagcag acaagttatc
     6481 tcacaggtgc atttacaggg agcttgatcg gttctgatgg aacaaaatcg tatgccattt
     6541 atgatttgaa aaaaccatta tttgatacat taaatggtgc tacagttaga gatttggata
     6601 ttaaaactgt ttctgctgat agtaaagaaa atgtcgcagc gctggcgaag gcagcgaata
     6661 gcgcgaatat taataatgtt gcagtagaag gaaaaatctc aggtgcgaaa tctgttgcgg
     6721 gattagtagc gagcgcaaca aatacagtga tagaaaacag ctcgtttaca gggaaactta
     6781 tcgcaaatca ccaggacagt aataaaaatg atactggagg aatagtaggt aatataacag
     6841 gaaatagttc gagagttaat aaagttaggg tagatgcctt aatctctact aatgcacgca
     6901 ataataacca aacagctgga gggatagtag gtagattaga aaatggtgca ttgatatcta
     6961 attcggttgc tactggagaa atacgaaatg gtcaaggata ttctagagtc ggaggaatag
     7021 taggatctac gtggcaaaac ggtcgagtaa ataatgttgt gagtaacgta gatgttggag
     7081 atggttatgt tatcaccggt gatcaatacg cagcagcaga tgtgaaaaat gcaagtacat
     7141 cagttgataa tagaaaagca gacagattcg ctacaaaatt atcaaaagac caaatagacg
     7201 cgaaagttgc tgattatgga atcacagtaa ctcttgatga tactgggcaa gatttaaaac
     7261 gtaatctaag agaagttgat tatacaagac taaataaagc agaagctgaa agaaaagtag
     7321 cttatagcaa catagaaaaa ctgatgccat tctacaataa agacctagta gttcactatg
     7381 gtaacaaagt agcgacaaca gataaacttt acactacaga attgttagat gttgtgccga
     7441 tgaaagatga tgaagtagta acggatatta ataataagaa aaattcaata aataaagtta
     7501 tgttacattt caaagataat acagtagaat acctagatgt aacattcaaa gaaaacttca
     7561 taaacagtca agtaatcgaa tacaatgtta caggaaaaga atatatattc acaccagaag
     7621 catttgtttc agactataca gcgataacga ataacgtact aagcgacttg caaaatgtaa
     7681 cacttaactc agaagctact aaaaaagtac taggagcagc gaatgatgca gccttagata
     7741 acctatactt agatagacaa tttgaagaag ttaaagctaa tatagcagaa cacctaagaa
     7801 aagtattagc gatggataaa tcaatcaata ctacaggaga cggtgtagtt gaatacgtaa
     7861 gtgagaaaat caaaaataac aaagaagcat ttatgctagg tcttacttat atgaaccgtt
     7921 ggtacgatat taattatggt aaaatgaata caaaagattt atctacgtac aagtttgact
     7981 ttaacggaaa taatgagact tcaacgttgg atactattgt cgcattagga aatagtggac
     8041 tagataacct gagagcttca aatactgtag gtttatatgc gaataaactt gcatcggtaa
     8101 aaggagaaga ttcagtcttt gacttcgtag aagcgtatag aaaactgttc ttaccaaaca
     8161 aaacaaataa cgagtggttt aaagaaaata caaaggcata tatagtcgaa atgaagtctg
     8221 atattgcaga agtacgagaa aaacaagaat caccaacagc cgatagaaaa tattcattag
     8281 gagtttacga tagaatatca gcaccaagtt gggggcataa gagtatgtta ttaccactac
     8341 taactttacc tgaagaatct gtgtatattt catcgaatat gtctacactt gcattcggtt
     8401 cgtatgaaag atatcgtgat agtgtggatg gagttattct ttcaggagat gctttacgaa
     8461 cttatgtaag aaatagagtt gatatagcag cgaaaaggca tagagaccat tatgatattt
     8521 ggtacaatct tcttgacagt gcttcaaaag aaaaactttt ccgttctgtg atagtttatg
     8581 atggattcaa tgtaaaagat gagacaggaa gaacttattg ggcaaggtta acggataaaa
     8641 acatcggctc tattaaagaa ttcttcggac ctgttgggaa atggtatgag tataatagta
     8701 gtgcaggagc gtatgcgaat ggaagtttaa cgcactttgt gttagataga ttattagatg
     8761 cttatggaac gtcggtttat actcatgaaa tggttcataa ttctgattct gcaatctact
     8821 ttgaaggaaa tggtagacgt gaaggattgg gagcggagtt atacgcactt ggtttactgc
     8881 aatctgtaga tagtgtaaat tctcatattt tagctttaaa tacgttatat aaagcagaaa
     8941 aagatgattt gaatagattg catacatata atccggtgga acgtttcgat tcggatgagg
     9001 cgcttcaaag ttatatgcat ggatcatatg atgtaatgta tacacttgat gcgatggaag
     9061 caaaagcgat attagctcaa aataatgatg ttaagaaaaa atggtttaga aaaatagaaa
     9121 attattacgt tcgtgatact agacataata aagatacaca tgcaggaaat aaagtccgtc
     9181 cattaacaga tgaagaagta gctaacttaa catcgttaaa ctcattaatc gacaacgaca
     9241 tcataaatag acgtagctat gatgataata gagaatataa acgaaatggc tactatacta
     9301 taagtatgtt ctctcctgta tacgcagcgc taagcaattc gaaaggtgct cctggagata
     9361 ttatgtttag aaaaatagct tatgaattac ttgcggaaaa aggttatcac aaaggattcc
     9421 taccttatgt ttctaatcag tacggagcag aagcatttgc cagcggaagc aaaacattct
     9481 catcatggca tggaagagat gttgctttag tgacagatga tttagtattt aagaaagtat
     9541 tcaatggtga gtactcatca tgggctgatt tcaaaaaagc aatgtttaaa caacgtatag
     9601 ataaacaaga taatctgaaa ccaataacaa ttcaatacga attaggtaat cctaatagta
     9661 caaaagaagt aactataaca acggctgcac aaatgcaaca attaattaat gaagcggctg
     9721 cgaaagatat tactaatata gatcgtgcaa cgagtcatac cccagcaagt tgggtgcatt
     9781 tattaaaaca aaaaatctat aatgcatatc ttcgcactac agatgacttt agaaattcta
     9841 tatataaata agattgtaga gtttcattgt tgagtagtgt ttcttgtaag gatgaggagt
     9901 cagatgacaa atcgactcct ttttcttatg gatcgatgta gagatttgat tgaatgcaga
     9961 ttgcaggaat catcttcaac tcatcaacga ccaatggtga caaggtggat ttcaatccca
    10021 cagaaaatgt tgatttgaga aataactttg ctagtctagt aaaataaata caaaacaatc
    10081 ctagaagatt ttttctggga ttgttttttg ctgagtggga tgcttcaagt tgtctggctt
    10141 gactttcttg agggaagtta tataatagtt gtaataatta aagttacaat aaaagaggaa
    10201 atatttatga catatgaata ccagagccac atttatttag cagaggcagt tttaaatgtg
    10261 aaggatttgg tcagtcaaac agttttttat cagcagatta ttggtttaga aatcctatct
    10321 caaacggata cagaggtcgt tctgggactt ggaggaaaag ccttggtaca cttgattcaa
    10381 gcacaagagg gtggagaagt aagggaacat tatggtcttt accatctggc tattcttttg
    10441 ccgacacgaa aggctttggc ggatgtcttg aagcacctga cggatttaca gattcctctt
    10501 gttggcggtg cagatcacgg ttacagtgag gccctttact tagaggactt ggagggaaat
    10561 ggcattgaac tctatcgaga taagccagtt tccacatggg atattcgaga agatggacgt
    10621 attatcgggg tgactgaagt ccttgcggct caggatatct atgagttggg ggaaagagta
    10681 gagcctttta tcctagcaga gggtacgaga atggggcata ttcatctttc tgtcaaggat
    10741 agtcgaaagt ccagacagtt ttatcaaacg gtgttagggc tcgaggataa attcagtgtg
    10801 cctagtgcta gttggatcgc agctggggac taccatcatc atttagcagt caacgaatgg
    10861 ggaggaaaag gtctggatcc gcgtaaacaa gtcctaccag gtttagccta ctatgtcatc
    10921 gaagtcgcac ataaagaaga actgttaacg attgcccaac gagcacaaga agttgacgca
    10981 ccaatcaaat ggatgacatc gatccaattg gaaatcacag actcagatgg catcgtgacc
    11041 cgtattcgtt tagctagata gatggtatgt gatgaaggta gagcatcaat tgtagaaagt
    11101 gctccttatt ctagtcagat acgtggaaaa tttgatatga tagtagggaa taaggagaag
    11161 aataatatga ctagcgaata ccagaaaatg atagcaggag agttttaccg tccatcagac
    11221 ccagaactga gagccttagc tcaggcttct cgccaaaaac aggccgcctt taacaaggaa
    11281 gagaacccct tgaagggagc cgaaatcatc aagacttggt ttgcctcaac cgggaaaaat
    11341 ctttacatca acactcgctt gatggtggac tacggtgtca acatccatct aggggaaaat
    11401 ttttattcta attggaactt gaccatgctg gatatctgtc ccattcgtat cggggacaat
    11461 gctatgattg gtcctaattg tcagtttttg acacccctcc atccactaga tccacaggaa
    11521 cgcaattcag gtatcgagta cggaaagcct atcacaatcg gagataattt ctggactggt
    11581 ggtggcgtca ttgtccttcc tggagtgaca ctgggaaata atgtcgttgc aggagcaggg
    11641 gcagtaatta ccaaatcttt tggcgacaac gttgtcctag ctggcaatcc tgcgcgcgtg
    11701 attaaggaaa tacctgttaa atagaagtaa aaaggaacag ctggggttgt ttcttttttg
    11761 taggtttcat cattttttac ccagttcaca tttacctact ctatctctta gcaagtctgt
    11821 ttcattaagc aagttcaaag catctcgtaa gtgggatgtt tttctcctca gttcatcagc
    11881 ttcctccttg acactcggtc agattttgat acaatagtac aaaattagag gaggcaggct
    11941 atgattcaga aacatgcgat tcctatttta gagtttgatg acaatcctca ggcggttatc
    12001 atgcccaatc acgaggggct ggacttgcag ttgccaaaga agtgtgttta tgcattttta
    12061 ggtgaggaga ttgaccgcta tgcgagggaa gtaggggcga actgtgttgg cgaatttgtt
    12121 tctgccacca agacctatcc agtttatgtc gtgaactaca aggacgagga gatttgtctg
    12181 gttcaggctc ctgtcggttc agctccagca gcccagttta tggattggtt gattggctat
    12241 ggtgtggagc agattatctc tactgggacc tgtggtgtcc tagctgatat agaggaaaat
    12301 gcctttctag tccctgttcg cgctctgcga gatgaaggag ccagttacca ctatgtggca
    12361 ccttctcgtt atatggaaat gcagccagag gctattgctg ccattgagcg agttttggat
    12421 gatagaggga ttccttatga agaagtcatg acctggtcca cagatggttt ttaccgagaa
    12481 acggctgaaa aggtggctta tcgcaaggaa gaagactgtg ctgttgtgga gatggagtgt
    12541 tccgctcttg cggcagtagc tcaattgcgt ggggttctct ggggtgaatt gttgttcaca
    12601 gcagattctc tagcggactt ggaccagtac gacagtcgtg actggggctc ggaagctttt
    12661 aataaggcgc tagaactgag tttagcaagt gttcaccacc tttagttgta ctggcaaagg
    12721 atttgtttta tcataaaatg tctagctcat acttttcaaa aatatgttta aacgaggtca
    12781 ccttcctctt gtcctaggca tgttgaggtt gggaaaaatc tttaaaatca gaaaaacgta
    12841 tcatatcagg tgatgaaaac tttgacacta tgcgttttat gtcgataaga tttagagtga
    12901 gatgaaatga tactcttcga aaatctcttc aaaccaggtc agcttc
//
LOCUS       DBEJZJ010000041        12626 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000041 DBEJZJ010000000
VERSION     DBEJZJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.41"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..290)
                     /locus_tag="ACL3R8_001716"
                     /pseudo
     CDS             complement(1..290)
                     /locus_tag="ACL3R8_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(352..801)
                     /locus_tag="ACL3R8_001717"
     CDS             complement(352..801)
                     /locus_tag="ACL3R8_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR1314554.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(803..1561)
                     /locus_tag="ACL3R8_001718"
     CDS             complement(803..1561)
                     /locus_tag="ACL3R8_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR1314555.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1677..3656)
                     /gene="stkP"
                     /locus_tag="ACL3R8_001719"
     CDS             complement(1677..3656)
                     /gene="stkP"
                     /locus_tag="ACL3R8_001719"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR1314556.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3653..4393)
                     /locus_tag="ACL3R8_001720"
     CDS             complement(3653..4393)
                     /locus_tag="ACL3R8_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR1314557.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4408..5721)
                     /gene="rsmB"
                     /locus_tag="ACL3R8_001721"
     CDS             complement(4408..5721)
                     /gene="rsmB"
                     /locus_tag="ACL3R8_001721"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR1314558.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFTNGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5714..6649)
                     /gene="fmt"
                     /locus_tag="ACL3R8_001722"
     CDS             complement(5714..6649)
                     /gene="fmt"
                     /locus_tag="ACL3R8_001722"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR1314559.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKSEEEKLNWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6662..9058)
                     /locus_tag="ACL3R8_001723"
     CDS             complement(6662..9058)
                     /locus_tag="ACL3R8_001723"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR1314560.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQMVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9124..9438)
                     /gene="rpoZ"
                     /locus_tag="ACL3R8_001724"
     CDS             complement(9124..9438)
                     /gene="rpoZ"
                     /locus_tag="ACL3R8_001724"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR1314561.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9463..10089)
                     /gene="gmk"
                     /locus_tag="ACL3R8_001725"
     CDS             complement(9463..10089)
                     /gene="gmk"
                     /locus_tag="ACL3R8_001725"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR1314562.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10219..11832)
                     /locus_tag="ACL3R8_001726"
     CDS             complement(10219..11832)
                     /locus_tag="ACL3R8_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR1314563.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12023..12277)
                     /locus_tag="ACL3R8_001727"
     CDS             complement(12023..12277)
                     /locus_tag="ACL3R8_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGR1314564.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(12281..12535)
                     /locus_tag="ACL3R8_001728"
     CDS             complement(12281..12535)
                     /locus_tag="ACL3R8_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR1314565.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
BASE COUNT         3366 a         3008 c         2484 g         3768 t
ORIGIN      
        1 gatatccaaa gaaacaattc tcccttgact tgtgacaatc gcttgagcct tcatagcgtg
       61 gcattttttt taccagaatc attcgctaat tgtttttttt agggcgattg atttttactt
      121 ccgtcgcatc aatcattacc gtgtcttcag aactgagagg agttcttgaa atcgtaacac
      181 cacctttgaa caagagttac ttcaacccat tggctccgac ggagtaagtt gctttcgtgg
      241 ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt
      301 tgttaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac
      361 tcgatgtgtt tttatataat gatacagtct gagaatcact gttccgctag ccattccaat
      421 agagattacc aaagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc
      481 ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa
      541 aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac
      601 acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag
      661 caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg
      721 ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa
      781 taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc
      841 ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt
      901 tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg
      961 caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg
     1021 caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt
     1081 tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt
     1141 cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag
     1201 ttacctgcaa cttagtatag ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg
     1261 ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga
     1321 ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt
     1381 caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg
     1441 aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga
     1501 gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca
     1561 tgctttcctc cttttatcaa ctccctctat tctatcacaa atctggactc aaaaaaaaat
     1621 ctttgccatg aaatcatgac aaagattgat tactcatttt gattatccat ctgcttttaa
     1681 ggagtagctg aagttgtttt aggtttgtag attgaaatct tgactctagt cttatttagg
     1741 tctacctttt cacctgctct aggactttgt tcaacaacca tgccttctac actacctgca
     1801 ggcgctgtcg tcacttctac aacttctata ttagcttcct taatcccaac aatttgaatc
     1861 aaattgttct tagtaaactc caagctggaa ccaatgtaac tcggcatggc aacacttgta
     1921 acttttttag ctactgtcaa gacaatttga gtaggtttac tcacatcata agtcgttccg
     1981 gcacctggac tttgtttcat aatcgttcct ggttcgcttt cgctggactc ttcttcctct
     2041 atcttaatca aattctcagg aaccttcttc tgcttgagtt ctgagattac ttctgtagag
     2101 ttccgtccaa tatagttccc taattgaatc gtcgtagctt ttttagctac tgtcaaaaca
     2161 atttgagttg ccttactcaa gtcataggtc gtaccttctg gtagactttg cttcaggacc
     2221 gttccagcct cactctcatt cgactcttct tcctcaattt taatcaaatt atctggaact
     2281 tttttctctt ttaattccgc gataacatca gaagatttcc ggccgacata attactaatt
     2341 tggaaggatt gtttgcctga tgagacaacc agattgattt tcgttccttc ttttcgacca
     2401 gttccagcgc caggatctgt acggataatc cgcccttctt ccaccttttc actagcctct
     2461 gtcttctcct caccaatctc aaaattggct tttttgagcg ttgccttggc ctctgcaact
     2521 gtctgacctg ccacatctgg aatggcaatg gttgcaggag ttctggatag tatccaaata
     2581 agagaagctg ccaccaatac aaggctggcc aacaaaatca ggtaacgcat cttaaatcta
     2641 tgttttttcg gtgcttgtgg ttggtaagtt tcctctgtca cagcctggct tgggtttttg
     2701 attgatttgt gttctgtctg cgcttgaacc ttaggaatag atgtcaaggt actctgagaa
     2761 accttcggca aggtcttggt atctgccttg ctcgtttcat caaagattaa cttactttca
     2821 tttctacgat tgtaggacaa gctactagac aagtccacat acatctctga aaccgagcgg
     2881 tagcgattgg tcaacttttt agcagttgcc ttgataataa cattttctaa agcctgaggt
     2941 acagatggat tttctgcaat aacggacggc aggggtttct ggaaatgctg gagggcaatg
     3001 gtcaccgcgc tatccccgtc ataagggata tggcctgtca acatctcata gaaaataatc
     3061 cccatggcat agatatcact ctgcacagtc gccttcgaac cacgcgcctg ctctggtgac
     3121 aagtaatgaa ctgagcccaa catcgagtta gtctgggtca gacttgtctc tgcaaaggct
     3181 acagcaatcc caaagtctgt gaccttggcc gtcccatctg gtgtcaaaag gatattttga
     3241 ggtttcaagt ccctgtgaac aattcctcga gtatgggcca agcgcatagc caagagaatt
     3301 tgtcccatga tacggactgc ttcttcatta gaaagaggat aatgttcctt gatatagcgt
     3361 ttgaggtcta gtccagcaac atactccatt gcaagatact gttgaccgtc ttcctcacca
     3421 atatctgtta tccgaacgat atgaggatgg tctagatctg ccatagctct cgcttcacgc
     3481 tgaaaacgag ctacagctat cgggtccgtc tggtagttgg tcctcagaac cttcactgcc
     3541 acttcttccc catctaagat taagtctttg gctaggtaga catccgccat gcctcctcga
     3601 ccaatctgtt tgacaatccg atagcgtccg gcaaaaatct tgccgatttg gatcattctt
     3661 catcctcctc gttcatagaa acaagggcaa ccgtaatgtt gtctaaacct cctgcattgt
     3721 tagcaaaacg aacaagtgtc tccgttttat ctgctaaagg aatatcactg gttacaatat
     3781 cacgaatctc actgcctgaa atcatgttgg tcaagccgtc actattgagc aagagatagt
     3841 cacctgactc aaggataact gtcccaaaat caggctgaat ttcatctttt tgcccaatag
     3901 actgggtgat aatatttttt tgcggatgag cttctgcctc ttctggtgtc aattgaccag
     3961 ccttgagcaa ttcattaacc aaggaatgat cgctcgtcaa ctgatggtat tcttctccac
     4021 gaatcaagcc gatacgcgaa tcaccaatat gagcatagat agcctgatta tcaataatag
     4081 caaggacttc caaagtagtt cccatacctc tgtaagcttc atcctgacca agctggtgaa
     4141 tcttttgatt ttcaatttct aggtaatggg cgaaccattc acgcacttca ttgactgtat
     4201 cgatctgggt atcaacccaa gctacaccca ggtctgtgac cgccatttca ctagcgatat
     4261 tccctgcacg atgacctccc atcccatcag ctaaaataat catggtacgt ccagctctat
     4321 tgacatagtg gttgacatag tcttggttat ttgttcgttt ctgaccaaca tctgttaata
     4381 atgaaatttc catgtgtcag ttccttccta atccgatatc ttgcgaaatt gactgatgaa
     4441 gaatccatca cttccataca attcaggtgt aatgaggata cagccgtctt tcatgatatc
     4501 cttacattca tgttctagtt ttacctgctc gaactcggga tgactctcta aaaaggcctt
     4561 aacgacttga aaattctcct ctgagacgat agtgcaggtg ctataagtta ttataccacc
     4621 tttgcctagt atttgacaaa cactacctaa tatttctaac tgaatttcct gcaaggacgc
     4681 gaaatctgcc gtttctttat tgtatttgat atctggtttt cggcgcaaaa gaccgattcc
     4741 tgaacaagga gcatccacca aaatcttatc aaaggaatcc tggtcaaaaa actcatgcac
     4801 ctttctggca tctaattttt gagtttgaac ccgatctgca actcccagac gttgggcatt
     4861 ttcttggatt aaatccaact tgtggtcgta caagtccaga gcagtaacct gacctgtcgt
     4921 aagataagag gctatatggg ctgttttccc acctggagcc gcacaggcat caagcactcg
     4981 ctcatcacct tgtaaatcaa gcgtcggagc aaccagctga ctggactcgt cttggatggt
     5041 aatggctcca ttcgtaaaca aattatgccc tgcaaaatgc ccttgctcct taaccagacc
     5101 agtggttgct aaaagggaat tattcgcctc caacaaggct tggatttcct cttttcgact
     5161 taggtctgtt acacgaatac tggctttgtt tcgcactaac aggctttcaa agatggcttt
     5221 tgctctctcc tctccgtatt cttccttgag tttggcaact agccaaactg ggagagaata
     5281 ggcaatggag tcacgcttgt tttttcgctt gatgctagca atatctggcc agccttcacg
     5341 caagatacgg cgaaggacag cgttgaccaa tttttcactg ccttttttac ggagtttggc
     5401 caattccact gcttcattga ccacagcatg atctggaatc ttgtccaaat agcggagttg
     5461 gtaggcactc atgagaagaa ggacatagag ccagctgtct aactggtctc tgtcttcgat
     5521 aaagtgggat aggtaccatt ccagagtcag tttacgggct accgttccat agaccagctc
     5581 ggtcactaag cccttgtctg ctgcagagag ctgactcccc ttgaggtgtt tatttaaggc
     5641 aatatttgaa tatgcttgat tcacaaaaac atcctctagc actgctagag ctaaacttct
     5701 agccgtttct actttagtca ccaaatcgtt ctcctacagt caatgtacgt ccaactccgt
     5761 tgaggaagga agcaatgtcc atcttaggct taccagctgg ctgcacttgt ttgagggata
     5821 gagccccttc agccgttgcg acaatcaatt ctttcttgcc gatagagaga atctcacctg
     5881 gatttccctg accttctact ggtagggctt cataaatctt aaagcggtca cccttaagga
     5941 aagtatgggc aacaggccag gggttcattc cacgaatttg gttaaagagt tgacgattgg
     6001 ttttgttcca gttcagtttt tcttcctctg actttatatt tggagagaag gtaacctgac
     6061 tcgtatcctg cggttcaggt ttgatatcac cagcaatata ggcaggcaga gtgtccaaaa
     6121 gcaaatcacg accaactagc gccaattttt caaacaaggt gccaacattg tcctcatctg
     6181 tgatcggaat gctgcgacga gaaatcatat ctcctgcatc catttcctta accatttcca
     6241 tgatggtcac accagcttcc tcatcccctt gaatcaaggc ataatggata ggcgcaccac
     6301 cacggtgtct aggaaggagg gaggcatgaa cgttgacagc aaagtccatg ctatcaagga
     6361 gtttgcttgg gagaaactgc ccaaaagcag cagtcacaat tccatctgct cctagcttca
     6421 taagatcttc catctctgga cttccagata atttttcagg ttgatagata gataatcctg
     6481 cttccttggc agcctgcttg actggggttt cttggataac ttttttacga ccaacagcac
     6541 ggtctggctg ggtcacaacg gctagaattt cgtaacggtc atctgtcaaa agtcctttta
     6601 agactgttgc tgaaaagtcg ggggtcccca taaagattag ttttgtcata tcttctcctt
     6661 cttataaaaa ttgctgcggc tcatggtcaa tgctgagacg gagctcacta ttttcccgtt
     6721 cttgagtcaa ggccaggacc tggttgaggg tcggccccag ctcatcttct aaacggtatt
     6781 taattaaaat ctggtaatga tagaggttgt gggtacgggc aatcggtttt ggcgttggcc
     6841 ccagaatggg actggtctct gacaagcctg accgcaaaat gttcatgact tcataggcac
     6901 gtttgaaaac ctcttcttct ttcttgtgag aaagggtaat accaatcgtg aaatagtaag
     6961 gtggatagcc gagttgtcgt ctgattccca tttcataggc ataaaagcct tcgtaatctt
     7021 gatccttggc aaatcgaata gcatagtgct gcggattgta ggactgtatc aagacttgac
     7081 ctgctttttc agcccgacct gctcgacctg ccacctgagt caagagctgg aaggttctct
     7141 cagaagaacg gaaatcaggc agattcaagg ccgtatccgc atttagaact ccgactaggg
     7201 taacattggg aaaatccaaa ccctttgcaa tcatctgagt accaagtaaa atatccgctt
     7261 cccctcgccc aaactggtca agcaaggctt ggtgactgcc tttctttcga gtcgtatcca
     7321 catccatcct caaaatgcga gcttggggaa agagttctgc tagctcatca taagccttct
     7381 gagttcccgt cccatagtaa cgaatactgt ggctcttaca gttaggacag acctgaggaa
     7441 tatccttcga gaaaccacaa taatggcagt tcatagtctt ggtatccata tgcaaggtca
     7501 gagaaatatc gcagttggga caagtatcca ccgtcccaca ctcccgacac atgacaaagc
     7561 tagaataacc acggcgattg agcatgagaa ccatctgctc ttttttaacc agacggtctt
     7621 ggatagcctc tagcaaagga ggcgtaaagt ttgacgtctc attttgtccg atatagtctc
     7681 gaaagtcaat cacttgaacc tcagggattg tagccaaagg attggcacgt tgggttagac
     7741 gtaagtgttg atagacgcct ttgccagcac gtgcccggct ctctaagctc ggcgttgcag
     7801 atccaagtac cagagttgct tgattatact gagcccgtaa aatagctacc tctctggcat
     7861 ggtaacgggg attgctgtcc tgcttataag ccgcttcatg ctcttcatca ataatcatga
     7921 cacccagatt tttcagagga gcaaagatag cagatctggc accaacaaca acttgggcat
     7981 cgccacgctc caccttgcgc cattcatcat acttttcacc attggataat cctgagtgaa
     8041 gaatggctac cttgtcccca aaacgtgcta taaaacgctc ggtcatctga ggagtcaagg
     8101 aaatctcagg taccagcaaa atagctgtct tgcccttatc cagggcacct tggataatct
     8161 gcaagtaaac ctcggtcttc ccacttcctg taatcccttg aagtagaaag ggaggttgag
     8221 aactgccaat agaactcaca accgcatcac gcgcctgtct ttgttctgga tttaactcca
     8281 aaggtctact tgcttcaatt ccttcaaaat aagcagccga gcgtcgaact tccttttgga
     8341 ctatagtaac agcaccttga tccacaaaga agttaacttg ctctcgcgag taggactcta
     8401 acaagctagc caaggaagcg ctctctggat gagacagcag ataatctctc agttccaact
     8461 ttttcttggc acgtgtagaa atctcaacac cttctaattg agcatggtca acctcatacc
     8521 aagactgggt cttgaccttc ttttgatcga ctgcctgata ttccagacca agcaggcctt
     8581 ttctagtcaa acgcatcatt tcagcttgct tacctaaatc cagagaagaa aaggctagcg
     8641 aatcttctga atcaaacagg cgtactcgtt cttcctgact caagccttcc agaggataga
     8701 gaatcttgtc atagctagaa ttcagaaatc ccggaagcat ggccttgagg atagagattt
     8761 tgtaggagaa gacagatttg cgtaactcct cagccagcca gagttgttct ggcgtgagaa
     8821 caggagaaaa atccagcacc tctgcaatat cttttaaatc ttgctccatc tcttctccat
     8881 ctgattggga ctccaaacca agaacaatcc cttgaatcag gcgattaccc ttaccaaaag
     8941 gcacatgaac ccgcatccca acttccagca ttccctcaaa ttcctccgga atcctgtaac
     9001 tatagggctg gtccgtctgc atcaagggca catctacgat aatcttagct agggccatct
     9061 tctcacctcc tccttgtcag tacattcttg caatagaaaa aataagattg agtcccccca
     9121 accttaaatt ttttcaccat cttctttttc tttagcaatt tgctctttga ttttcttttc
     9181 ttcttcttct ttgcggcgtt tttcttcttc gatacggcga cgcactgctt cacgttttcc
     9241 ttctggatct gggtgaattg taacgtttcc tgattcgatt tcttctaaag cgcgaagagt
     9301 tgatttttca gacttgaaac cttgagttgc tggggcacct gcttccaatt cgtgggcacg
     9361 ttttgcttcc aagattacga gtgaatattt tgaaggaacc ttgtcgagca aggtatcaat
     9421 agagggtttt aacatcattt gcttgtacct attttctaaa ttttatcggg tagttggaga
     9481 ttttggtaac atctcctgat agtgaccaat gacacgatcc acacagaagt gttctgcttc
     9541 aatcacacat ttgacacgtt cagcagctag gggcacctga tcgttgacaa tcgcataatc
     9601 atactcacgc atgagggcaa tttcttcctt ggccttttcg attcgttggg caatcacttc
     9661 tgcactatct gttccacgac ctaccaagcg atcttgcaat tcatccaaat ctggtggtgt
     9721 caggaagata aagacagcat ctggaacctt tttcttgacc tgaagagcac cctgaacttc
     9781 aatttcaagg aaaacatcga ttcccttgtc caaggtttca ttgacatagg tcagaggagt
     9841 tccatagtag ttgccgacat attctgcgta ttccaacatc tgtccttgac gaatcagctc
     9901 ttcaaattct tcacgagtac ggaagaaata gtcaacaccg tccacttctc caggacgttg
     9961 tgcgcgtgtc gtcatcgata cagaatattg aaattggttt tcagaactct caaaaatctc
    10021 tcttctaacc gttccttttc caacccctga aggaccagaa aaaacgatta gtaagcctcg
    10081 gtctgccatt gtgtctcctt ttagtcaatc tgtgaaataa catttctcta gaataatggc
    10141 aaaaagccag attatccttt acagtctttc tatctagtgt aacaaaaaag cagtaatttt
    10201 tcaactgctc tttcttattt atttagcata atctactgca cgaagctcgc gaatcacggt
    10261 taccttgata tttcctggat aatcgagatt gttttcaatt ttcttacgaa ctttgtgagc
    10321 caagattgtg actttgtcgt ccttgatttt tcctggattg accatgatac gaatttcacg
    10381 tcctgcttga agggcaaagc tagtttgcac tccttcaaag ccgttagcaa tttcttccaa
    10441 atcatggaga cgcttgatgt agctttcaag agactcacta cgagcacctg gacgggctgc
    10501 gctcaaggca tctgctgcag cgacgataac tgctatcacg ctctcagctt caacatctcc
    10561 gtggtgacta gcaatcgtat tcaccacaac tgggggttcc ttgtacttac gggccaattc
    10621 cataccgatt tcaacgtggc taccttcaac ctcatggtca atggctttcc cgatatcgtg
    10681 aaggaatcca gcacgacggg caagagccgc attttcacca agttcgctcg ccatgatacc
    10741 agccaactta gcaacctcaa tcgaatggcg caaaacattt tgtccatatg aagtacggaa
    10801 ctgcaaacgt cccataatct tcatcaagtc tggatgaagg tttggcgcac caatttcata
    10861 ggcagcagcc tcaccgtatt cacgaatctt attgtcaatc tcttgacggt ttttctcaac
    10921 caactcttcg atacgagctg gatgtatacg accatctttg agcaacattt ccatagtcat
    10981 acgggcaatc tcacgacgaa tcggatcaaa tcctgacaag gtcaccactt ctggtgtatc
    11041 gtcgataatc acatcgaccc ctgtcaaact ttcaaaggta cgaatgttac gaccttcacg
    11101 accaataatg cgtcccttca tagtatcgtc tggcagatga actgttgagt ttgttgactc
    11161 cgctacatat tcaccagcga tacgttgcat agcttgaacc aagatgtcct tggccatttt
    11221 gtcagaacgt tccttgacct cttgctcagc ttcgcgaatg cgactggcaa tctccctggt
    11281 caagttttcc tctgtctgag ccaagataat atctcgtgct tctgcctgag acagagcacc
    11341 aatacgctct agttctgctt ctttttgtct ttcgacttcc tctaattgct cttcacgcgc
    11401 atcaaggttt ttcgctctat cagaaatact ttgttctttt tgttcaagtg tttgttcttt
    11461 actcgtcaaa ttgtcgtcct tacggtcaag gctagtagct ctctctgtca aacgactttc
    11521 gatttgtttg agttcttgac gttctgattt gaattcagcg tccacttctt cacggtattt
    11581 tctggcttct tctttggcct ccaatagtgc ttctttttta agagacttgc tttcacgttt
    11641 ggcttcatta acaagtaaat ccgcttcacg ctcagcttgt ccacgtaaat tagttgcttc
    11701 ttgttcagca tttaaaagca tcaactctgc agcttcctga gatgatttca tcttagctga
    11761 gatgctgaca tatccaatga ctaaaccaat gatgacggca aaaacagcaa tcgcaagcga
    11821 catgatttcc atgtttttac ctcattttat tgttattccg aatgacatac attcttttac
    11881 attctaccat aaaaaagtga ttttcacaaa cctaaaatag aatatgtttt ggggaatttg
    11941 gaacacattt gccaaaataa acttgttttt tagaaatagt agtttagtag agacttgaga
    12001 aaaagcctac ctttcaatag acttagtaat gatctttaaa ggacaagaaa gccacgctat
    12061 ctccatccat catataaatc aagcgatttt ctgcatcaat acgccgtgac caggctcctt
    12121 ggtaatcata tttgagtggc tctggttttc ctattcctgt aaatggatcg cgttgaatat
    12181 ccttgattaa tttattgatt ctttttagtg tttttttatc ttggttttgc cagtagcaat
    12241 aatctgccca cgcatcttct gtaaacttga gtagcattca tcactcctca atcacatgga
    12301 cctgaatgct tccagcacgg acttgagcca ttcctcgcaa aaccttgtct gataactcct
    12361 tattttgagc gattctcagg gtttcctgaa tactgtccca ttcgctcttt gaaagaacta
    12421 caatgtcctc atctggattt ttattgacca ccgtcaaagg ctcaaattca tcatttacct
    12481 tcttcatgta gtcctttaaa tgatttcgga atgttgagta aaggactgct tccataacca
    12541 tacctcgttt tagctctttt ccactattat acacgaaaag aaagaaattg tcaggaactt
    12601 gtacaagatt ttcttttcta tctatt
//
LOCUS       DBEJZJ010000042        12289 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000042 DBEJZJ010000000
VERSION     DBEJZJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.42"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(261..2519)
                     /locus_tag="ACL3R8_001729"
     CDS             complement(261..2519)
                     /locus_tag="ACL3R8_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1314566.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2748..2978)
                     /locus_tag="ACL3R8_001730"
     CDS             complement(2748..2978)
                     /locus_tag="ACL3R8_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR1314567.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3168..3851
                     /locus_tag="ACL3R8_001731"
     CDS             3168..3851
                     /locus_tag="ACL3R8_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR1314568.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3851..4585
                     /locus_tag="ACL3R8_001732"
     CDS             3851..4585
                     /locus_tag="ACL3R8_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR1314569.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQILSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4739..5596
                     /locus_tag="ACL3R8_001733"
     CDS             4739..5596
                     /locus_tag="ACL3R8_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR1314570.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5738..6610
                     /locus_tag="ACL3R8_001734"
     CDS             5738..6610
                     /locus_tag="ACL3R8_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR1314571.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6892..7575
                     /gene="rpiA"
                     /locus_tag="ACL3R8_001735"
     CDS             6892..7575
                     /gene="rpiA"
                     /locus_tag="ACL3R8_001735"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR1314572.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7589..8800
                     /locus_tag="ACL3R8_001736"
     CDS             7589..8800
                     /locus_tag="ACL3R8_001736"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR1314573.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8802..9344
                     /locus_tag="ACL3R8_001737"
     CDS             8802..9344
                     /locus_tag="ACL3R8_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGR1314574.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9360..10169
                     /locus_tag="ACL3R8_001738"
     CDS             9360..10169
                     /locus_tag="ACL3R8_001738"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR1314575.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10645..11040
                     /locus_tag="ACL3R8_001739"
     CDS             10645..11040
                     /locus_tag="ACL3R8_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGR1314576.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11050..11625
                     /locus_tag="ACL3R8_001740"
     CDS             11050..11625
                     /locus_tag="ACL3R8_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR1314577.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11650..12162
                     /locus_tag="ACL3R8_001741"
     CDS             11650..12162
                     /locus_tag="ACL3R8_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGR1314578.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3637 a         2241 c         2778 g         3633 t
ORIGIN      
        1 ccaagttgcg atacctttta tgaggctctt ttgtcttgtt cttgtttcaa ttgactatag
       61 cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
      121 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
      181 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
      241 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
      301 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt
      361 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
      421 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgacctta
      481 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
      541 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
      601 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
      661 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
      721 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
      781 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
      841 tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc
      901 tcatcatagc caacataacc tggaggggcg ccgaccaact tagccacact atgtttttcc
      961 atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc
     1021 agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg
     1081 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     1141 tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag atggatgagt
     1201 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     1261 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     1321 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     1381 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     1441 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     1501 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     1561 gcagcatctg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     1621 atagtgattg tttcgtccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     1681 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     1741 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     1801 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     1861 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     1921 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     1981 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     2041 ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg
     2101 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     2161 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     2221 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     2281 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     2341 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     2401 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     2461 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     2521 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     2581 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     2641 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     2701 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     2761 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     2821 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     2881 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     2941 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     3001 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct
     3061 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     3121 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     3181 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     3241 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa
     3301 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     3361 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     3421 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     3481 atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt ccaaaaggtc
     3541 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     3601 tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     3661 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     3721 tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga
     3781 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     3841 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     3901 gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat
     3961 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     4021 aaccaagggg aagcttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt
     4081 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     4141 tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca gggaagttgc
     4201 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     4261 tccacagatt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg ggttggctat
     4321 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg
     4381 tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg ttatcgtaac
     4441 acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg cagacggtgt
     4501 ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa
     4561 agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     4621 gttcaaccag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     4681 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     4741 gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa
     4801 gactgcaaaa ttaaaggagg aaacagctct agtgcctggt ttggtagtga ttttggttgg
     4861 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     4921 ttcccgtagc gaagtagtgc gagttccaga gactattact caagaggaat tgttagacct
     4981 gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc
     5041 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     5101 tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac
     5161 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     5221 ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
     5281 aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg tggctgctaa
     5341 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
     5401 accaggtgcg gttgtcattg acgttgggat gaatcgagat gaaaatggga agctctgtgg
     5461 agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag tccctggagg
     5521 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
     5581 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
     5641 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
     5701 cctttttatt gtataataaa agtgagagga aaaaaggatg aaagtgatta atcaaacctt
     5761 attagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
     5821 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5881 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5941 gcacagccat ttacctgagt ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     6001 gcaattggag aaggcagaag ttgtcttgct ggggcctggt ttacgagacg atgcttctgg
     6061 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6121 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6181 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6241 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6301 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6361 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6421 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6481 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6541 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa gcaaagataa
     6601 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6661 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
     6721 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6781 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6841 aaaaagcggt ttcatagtaa aataagaatt gagaatgatg gaggtaaatc ggtggaaaat
     6901 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6961 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     7021 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7081 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7141 gcagatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7201 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7261 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7321 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7381 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7441 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7501 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7561 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7621 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7681 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc
     7741 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7801 agctgaaatc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7861 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7921 ctggaacgga ttcccagaag aaatcctgac aaaaattgaa gaattctcag gacgcaaggt
     7981 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     8041 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8101 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8161 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8221 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8281 aactgttttg gataaattga atgaggctga tatcgatact tatgctgtgg gtaaaatcaa
     8341 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8401 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8461 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8521 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8581 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8641 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8701 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
     8761 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8821 tggtgagagg tatcaatgtt ggtagtaaga ataaggtcgt catggcggag cttcatcaag
     8881 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
     8941 ttgcttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     9001 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9061 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9121 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9181 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9241 agactgccta tcagaagtat ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9301 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
     9361 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
     9421 cccctgagtt cggtctaatc cttgggtcag gacttggaga attggcagaa gaaatcgaaa
     9481 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
     9541 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaagggc
     9601 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
     9661 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc agatttggtc
     9721 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
     9781 gggaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag
     9841 aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagatt gatgaaggtg
     9901 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
     9961 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
    10021 ctggcttgaa agttctggga atttcatgta tcactaactt tgcggctggt ttccaagaag
    10081 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    10141 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaaggggg agtgcctctg
    10201 tcttttcagg attgactgcc tatccgtatt aaagaagaaa cagaggaata ctatgagctt
    10261 cttcctgctc ttataactga aagaagcgga agaataggtg tgtctgatct gatagccagc
    10321 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc agactagtat
    10381 gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca
    10441 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    10501 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    10561 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    10621 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    10681 aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg
    10741 cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca
    10801 gagccagctc aagcggatga tatccgcaag gttgttgggg aattagccaa ggatataagt
    10861 attactaagt tgtatatgac aggtcattct cttggaggct acctagctca gattgcagcg
    10921 gttgaagatt accaaaaata tcctgatttt tataaccatg tattgaggaa agtgacaact
    10981 ttcagtgctc ctaaagtgat tacttccaga actgtttggg atgctaagaa tggtttctga
    11041 gatgttggtt tggaaagtcg taaattagct gttagtggaa aaattaagca ttatgtggtt
    11101 gataatgaca atgttgtgac tcccttgatt cataataatc gtgatattgt tacatttaca
    11161 ggtaattcac gctttaaaca ccgttctcgt ggctattttg aaagtccaat gaatgatatt
    11221 cctaacttta atattggtaa acaagctacc ttggataaac atggttatcg tgatccgaaa
    11281 ttggataaag cgcgattctt taagaaacag gctctacctc aatcttctag tcaaccaagc
    11341 gctgaaccaa tggaaaatat tgccttagga aaacaggtta ctcaaagttc gacagctttc
    11401 ggaggagatg ctagaagagc tgtggatggc aaagtcgatg gtaactatgg tcacaattct
    11461 gtcactcata caaacttcca atctaagcct tggtggcaag tagatttggc taaagaagaa
    11521 accattcgcc aaatcaatat ttacaaccga acagacactg cccaggatag attggcaaac
    11581 tttgatgtca ttcttttaga cggttctggt aaagaaattg agtgaaaacg tataatatct
    11641 cctaaagatg tgtcagcaca aattacgatt aaccataaaa aagcgcgcta tgttcggatt
    11701 gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg ctttatagct
    11761 acgaatggtg aaacggcgat acaagtttct aagtcagttc aaccaatcag tcagactcct
    11821 gtgaaagata aaacattgac aattcaacac agtggagctt acattgcccg ctactccata
    11881 acttgggaag aagttacagt agataaagat ggaaaccaag ttgttcgtag tcattcttgg
    11941 gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat caaagaaaat
    12001 atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa tagatggcaa
    12061 acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac ccattggggt
    12121 acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg tacaatgaca
    12181 gttagtttgt ctagtttata agaaagtact acctgagctt gaatagaact caggtagctc
    12241 tctgtgaaag aacaaaatta atactcaatg aaaatcaaag agcaaacta
//
LOCUS       DBEJZJ010000043        12096 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000043 DBEJZJ010000000
VERSION     DBEJZJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.43"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..1623
                     /locus_tag="ACL3R8_001742"
     CDS             <1..1623
                     /locus_tag="ACL3R8_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314579.1"
                     /translation="DVVKFLYELVKSKKLFIEEEKFLESDSEDLISTILIQKLLVQLD
                     NEINLDLEFIKRLIDKIDFSNIHFGEELNTFIKEHRSIIREKNIEIPKKTYRNWISSL
                     EGGFVSQFSYLTQENLVEYDESRVLEILVNAEKEQRGSSFLEEKTINETENFFITVLK
                     ESNEISKKVSDLLKNHIDDLYPKYKRLYVKIISFPEIEENLRKIVREKYLKRFNKESF
                     DSNDRKFFEYHIKQQNTDIDIFEKLLSINVNELSTPKGDNKQLDILHFINSEMGSYFQ
                     CLISLFINHSSYRDVIIQIINSVTDTDYREFAQGILLNEYNPNRINVTYNTFLGFAYY
                     HSTITIEAADVFTDVVRNILNKKIEDNQILNKVYLVALERVDPTIESFSLSKNNYSQM
                     INIIFTGDYEFRYSKEWLGALFKFDSSANYLVTIFYLLYNENLKKNRFALFIEELSDY
                     LTTYNQKLSLRGMNYKLNHEELNNFDLLKKMFLKLMETDKIENDIFYLDGIKSILPLL
                     SLDDRRNVLQHIQKQNNCPPPEIEELQRIIVN"
     gene            1724..2602
                     /gene="truB"
                     /locus_tag="ACL3R8_001743"
     CDS             1724..2602
                     /gene="truB"
                     /locus_tag="ACL3R8_001743"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR1314580.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            2843..3145
                     /locus_tag="ACL3R8_001744"
     CDS             2843..3145
                     /locus_tag="ACL3R8_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR1314581.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            3253..3891
                     /gene="udk"
                     /locus_tag="ACL3R8_001745"
     CDS             3253..3891
                     /gene="udk"
                     /locus_tag="ACL3R8_001745"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR1314582.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            4019..5359
                     /gene="xseA"
                     /locus_tag="ACL3R8_001746"
     CDS             4019..5359
                     /gene="xseA"
                     /locus_tag="ACL3R8_001746"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR1314583.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            5337..5549
                     /locus_tag="ACL3R8_001747"
     CDS             5337..5549
                     /locus_tag="ACL3R8_001747"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR1314584.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            5546..6421
                     /locus_tag="ACL3R8_001748"
     CDS             5546..6421
                     /locus_tag="ACL3R8_001748"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR1314585.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            6414..7229
                     /locus_tag="ACL3R8_001749"
     CDS             6414..7229
                     /locus_tag="ACL3R8_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR1314586.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     NLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            7222..7653
                     /locus_tag="ACL3R8_001750"
     CDS             7222..7653
                     /locus_tag="ACL3R8_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1314587.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            7660..9327
                     /gene="recN"
                     /locus_tag="ACL3R8_001751"
     CDS             7660..9327
                     /gene="recN"
                     /locus_tag="ACL3R8_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR1314588.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMTEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            9329..10057
                     /locus_tag="ACL3R8_001752"
     CDS             9329..10057
                     /locus_tag="ACL3R8_001752"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR1314589.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            10136..11959
                     /gene="lepA"
                     /locus_tag="ACL3R8_001753"
     CDS             10136..11959
                     /gene="lepA"
                     /locus_tag="ACL3R8_001753"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR1314590.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         3748 a         2063 c         2809 g         3476 t
ORIGIN      
        1 gatgttgtta aatttcttta tgagcttgta aagtccaaaa aattatttat tgaagaggaa
       61 aagtttttag aaagtgattc tgaagactta ataagtacta tattaattca aaaattgctt
      121 gttcaattgg ataatgaaat taatttggat ttagaattta tcaagaggtt aattgataaa
      181 attgattttt caaatattca ctttggagag gaattaaaca cttttatcaa agaacataga
      241 agtattatta gagaaaaaaa tattgaaata ccaaaaaaaa cttatagaaa ttggatatct
      301 tcactagaag gaggttttgt ttcacaattt tcatatttaa ctcaagaaaa tcttgtagag
      361 tacgatgaat ctagagtatt agagatatta gtcaacgccg aaaaggaaca aagaggttct
      421 tcatttttgg aagaaaagac gataaatgaa acggaaaatt tctttattac tgttttaaaa
      481 gaatcaaatg aaatatctaa aaaagtttct gatttattga aaaatcatat agatgactta
      541 tatccaaaat ataagagatt atatgtaaaa attatcagtt ttcctgaaat agaagaaaat
      601 ttgagaaaga ttgttagaga aaaatattta aaaagattta acaaagaaag ttttgattct
      661 aacgatcgga aattctttga atatcatata aaacaacaaa atacggatat agatattttt
      721 gaaaaattac ttagtatcaa tgtgaatgaa ctctcaacac caaaaggtga taataaacaa
      781 ttagatatac ttcattttat aaatagtgaa atgggatcat attttcaatg tttaatatca
      841 ttatttataa atcattcaag ttatagagat gtaattattc aaataataaa ttcagtaaca
      901 gataccgatt atagggagtt tgctcaaggt attttattaa atgaatacaa tccaaacaga
      961 atcaatgtaa cttacaacac ctttttagga tttgcgtatt atcattctac aattactatc
     1021 gaagctgcgg atgttttcac agatgtagta aggaatattc taaacaaaaa aattgaggac
     1081 aatcaaattc ttaataaagt ttatctagtt gctttagaga gggtagatcc aactattgaa
     1141 tcattttctt tatcaaagaa taactatagt caaatgataa acatcatttt tacaggagac
     1201 tatgaattta gatattctaa agaatggttg ggagcattat tcaaatttga ctcaagtgca
     1261 aattatttgg tgacaatttt ttatttatta tataatgaaa atcttaaaaa aaatagattt
     1321 gctttgttta tagaggaatt gagtgattac ttaacaactt ataaccagaa attatcttta
     1381 cgagggatga attataaatt gaatcatgaa gaacttaaca attttgattt gttgaaaaaa
     1441 atgtttctga aattaatgga gaccgataaa atagagaatg atatttttta tttagatggc
     1501 atcaaaagta tactcccatt attatcttta gatgacagac gaaatgtatt acaacatatt
     1561 caaaaacaga acaattgtcc tcctccagag attgaggaat tacaaagaat tatagttaat
     1621 taaattttgt aaaaaagaga ataaaaggta gacgacgcct cagtaaaaat tggcccggaa
     1681 aaaagcgaag ttcgaagcac tgaaggggga gtagaaagca aaaatgaacg gtattatcaa
     1741 cttaaaaaaa gaagcaggaa tgacctcgca tgatgcggtt tttaaactgc gtaagatttt
     1801 gggaaccaag aaaattggtc atggtggaac cttggatccg gatgtggtgg gtgttttgcc
     1861 gattgcggtt ggcaaggcga cacgcatggt cgagtttatg caggacgagg gtaagatcta
     1921 tgagggggaa attactctgg gttattccac gacgactgag gatgctagtg gggaagtgat
     1981 cgcagaaacc cctgttttgt ctcccttgga tgaaaagctt gttgatgaag cgattgctag
     2041 cttgactggg cctattaccc agattccccc tatgtattcg gcagttaagg ttaatggtcg
     2101 caagctctat gagtatgcgc gtgctggtca ggaagtggag cgtccagaac gtcaggtgac
     2161 catttatcaa tttgagcgaa caagtccgat ttcttatgat ggccaacttg ctcgattcac
     2221 ttttcgtgta aaatgcagta aagggactta catccgtact ttgtcagttg atttgggtga
     2281 aaagcttggt tatgcggctc atatgtccca tttgactcgt actagtgctg ctggcttaca
     2341 attagaagac gctcttgcct tggaggaaat tgctgaaaaa gtagaggctg ggcaattaga
     2401 ttttctccat cctttagaga ttgggacagg tgaccttgtc aaagttttcc taactccaga
     2461 agaggctaca gaagttcgct ttggtcgttt tattgagcta gaccaaacgg acaaagaact
     2521 ggctgccttt gaagatgata aattgttagc cattctagaa aaacggggca atctctataa
     2581 gccaaggaag gtttttagct agatcgttta ggaataaaaa tcgggtgata gataacaatt
     2641 gcttgataaa accccatact aatagtagaa tggttttggg aattataata ttccaattgt
     2701 tgcgagttgt aggtactcaa ataatctata tagaaattta gaggtgtgaa atgaagcaat
     2761 ttaaaattct ttcagataaa tatttagagt ccattacagg ttctggtggg aacttaggcc
     2821 caggatttgg tgtgataatt ccatgatgcg aaatgagttt cgagaaaggg tggagcaact
     2881 tcttcaacaa aaagaaataa atgaaaatag tgagttgagt cacctgtttc gtcttgctat
     2941 acaaaattta gacagaaatg aaaaatacca atcggtcatg gccaatttga gtcaagggtt
     3001 gtcactttac ctcatgacgc atcattacca ggcacctaag tctgtcattg attttggttt
     3061 atggattgcc aaagctccta gccaggaaag agggagactg gctttcttgc agatgcttgc
     3121 tcaaacccta cagggctttc gttaaaactg tcgaacatca gagggaagac tctggtgttt
     3181 tttgctgatg agactataaa ttttgtaaaa aatgtgatag aatagacgac ggataaaata
     3241 acggaggata gcatgcaaaa tagaccaatc attattggag tgacaggtgg ttctggtggt
     3301 ggtaaaacca gtgtttcaag agccatttta tcgcattttc ctgatgaaaa gatttccatg
     3361 attgagcatg attcatacta caaggatcag tctcatttga cctttgaaga gcgtgtcaaa
     3421 accaactatg accatccttt tgcctttgat acagacttga tgatcgagca gattaaggaa
     3481 ttgttggcag ggcgtccggt ggacatcccg acctacgact atacagagca tacacggagt
     3541 agcaagacct atcgtcagga gcctcaagat gtctttatcg ttgagggcat tttggtcttg
     3601 gaggacaagc gtctgcgcga tttgatggat atcaagattt ttgtggatac ggatgacgat
     3661 gtacgtatta ttcgtcgtat caagcgtgat atggaggagc gtggccgtag ccttgatagc
     3721 gttattaacc agtacttagg tgtggtcaaa ccaatgtacc accagtttat cgagtcaact
     3781 aagcgttatg ctgatatcgt cattcctgaa ggggttagca ataccgtggc tatcgacctg
     3841 ttgacgacca agattgcaaa gattttggaa gaagctcgaa acagcaaata atcacatgtg
     3901 gaggccttgc ctcctttttc tatttttccc tcataatggt acataaatgg agatttttag
     3961 gcatattttt ggtataataa tacccatgaa agagcaagta aatgaatagt aggtggagat
     4021 ggaaaagtat ttatcggtaa caactttgac caagtatctg aaaatgaaat tcgataaaga
     4081 cccatacttg gaacgggtct atttaactgg tcaagtttcc aactttcgta aacgacctac
     4141 tcaccaatat ttctccctaa aggatgacca tgcagttatt caagcgacca tctggtctgg
     4201 gatttatcag aaattagggt ttgacctgga agaaggaatg aagatcaatg tgattgggcg
     4261 tgtacaggtc tatgaaccaa gtggtagcta ctccatcatc attgaaaaag ctgagcctga
     4321 tggggttggg gcgcttgcga ttcagtttga acaacttaag aaaaaattga cagaagaagg
     4381 cctgtttcaa gaacgcttca agcaagctct gccccaattt tctaagagaa ttggtgtagt
     4441 aaccagccgt agtggagccg ttattcgaga tattatcacg accgtcagca ggcgattccc
     4501 aggtgttgac atccttcttt atccgaccaa ggttcaaggt gaaggggctg cggaggaaat
     4561 tgctagaaat attgcgcgtg ctaatcaacg ggacgatttg gatttgctca ttattggtcg
     4621 tggaggtggt tctattgagg atctctgggc ctttaacgaa gaaattgtgg tacgagctat
     4681 ttttgaatct cgtttgccag ttatctctag tgtggggcat gagacggatg tgaccttggc
     4741 agattttgtg gcagatcgac gcgctgcaac gccaacagcg gcggctgaac tggcaacacc
     4801 tgtgaccaag ttggatgtat tagctcattt gcaaaatcag gaaaaacgga tggtaacggc
     4861 agtccgaaat gttctatcta agaaacaaga ggctttgaaa aaatgcagtc agtctgttat
     4921 ctttagacaa cctgagcgct tgtatgacgg ttatttgcaa cgcttggacc aactgcaact
     4981 gcgtttgaaa caaagtttgc gaactcggat ttctgataac aaacaattag ttcaagcaag
     5041 aactcatcaa ttagtacaat tatcacctgt taccaaaatc caacgctatc aagaccgttt
     5101 aggacagttg gacaagctct taggtagcca aatggcgtta gtttatgacg ccaaggttgc
     5161 tgaggccaag cgactttcgg aagctttgct catgttggat actagccgaa tcgtggcgcg
     5221 tggttatgct attgtcaaaa aagaagagtc cgttgtagat tcggttgaga gtttgaagaa
     5281 aaaagaccaa gtaacgcttt tgatgcgaga tggtcaagta gaattagagg ttaaagatgt
     5341 caaaacaaaa gaaatttgag gaaaatctag cagaactgga aaccattgtc caaagtttgg
     5401 aaaatggtga aattgatctg gaagatgcga ttactgcctt tcaaaagggc atggtcttgt
     5461 caaaagagct ccaagctacg ctggacaagg ctgaaaagac cttggtcaag gtcatgcaag
     5521 aagacggaac agaaagtgat tttgaatgaa aaagcaagaa aaattagctc ttgtcgagtc
     5581 ggctttggaa gatttttatg gagaccagca gtttgcctct agtttacggg agtctgttct
     5641 ctattctatt catgctggtg gcaagcgtat tcggcctttt ctcttgttag aagttctgga
     5701 agccttgcag gttaccatca aacctgctca cgcgcaggta gctactgcct tggagatgat
     5761 tcatacaggg agcttgattc acgatgacct tcctgctatg gatgatgacg attatcgaag
     5821 agggcggtta accaatcaca agaaattcgg tgaagctatg gccattttgg ctggagatgc
     5881 cttattctta gactcatatg ccttgattgc gcaggcagat ttgccaagtc agattaaggt
     5941 ggacttgatt gccaacttat cccttgcttc aggtagtctg ggtatggtgg cagggcaagt
     6001 tttggatatg gagggcgaac accagcactt gtctctggaa gaacttcaga ctattcatgc
     6061 caataagact gggaagttac tagcctatcc cttccaagcg gcagctatta tagctgaatt
     6121 gtcacctgaa atgcaggtga agctgaaaac tgtgggtgaa ttgattggac ttgcttttca
     6181 agtcagagat gatgtactgg atgtgacagc tagttttgag gaaatcggca agacacctca
     6241 aaaggatctg caggcagaaa aatcaaccta tcctgccctg ttgggcttgg aagagtccat
     6301 tgccttttgt aaccaaaccc tggatcaagc taatgaaaaa ttagaagaaa ttgcccagca
     6361 gcttcccttt gaaacagaat cgattgtaag tgtagtagaa agtttgagaa tcaatggcta
     6421 aggaaagagt ggatgtacta gcttataaac aggggttgtt tgaaacgaga gagcaggcca
     6481 agcgaggtgt gatggctggc ctagtcgtag cagtccttaa tggagaacgg tttgacaagc
     6541 caggagagaa aattccagat gacaccgaat taaaactcaa gggggagaaa ctcaagtatg
     6601 tcagccgtgg tggtttgaaa ctggaaaagg ccttgcaggt ctttgatttg tcggtggatg
     6661 gcgcgactac gattgatatc ggggcctcta ctggaggttt taccgatgtc atgctacaga
     6721 atagtgccaa gttggtcttt gcagtcgatg ttggtaccaa tcagttggct tggaaattac
     6781 gccaagaccc acgagttgtc agcatggagc agttcaattt ccgctatgct gaaaagactg
     6841 atttcgagca ggagccgagc tttgccagta ttgatgtgag tttcatttcc cttaatctga
     6901 ttttgccagc cttgcaccgt gtcttggctg atcaaggtca ggtggtagca cttgtcaaac
     6961 ctcagtttga ggcaggacgt gagcagattg ggaaaaatgg aattattcga gatgctaagg
     7021 ttcatcagaa tgtccttgaa tctgtaacag ctatggcagt agaggtaggt ttttcagtcc
     7081 ttggcttgga cttttctccc atccaaggtg gacatggaaa tattgaattt ttagcgtatt
     7141 tgaaaaaaga aaagtcagca agcaatcaga ttcttgctga gattaaagaa gcagtagaga
     7201 gggcgcatag tcaattcaaa aatgaataaa aaagaaagac ttgaaaaaat tagaagattg
     7261 gtgacagatt atcaaatcgg cacgcaagaa gaaattgtag aacatttgaa agaagcaggt
     7321 atcactgcca ctcaggcgac ggtatcccga gatatcaaag agttaggtat tgtcaaaatt
     7381 cctttgagag acaacactta tgtctacgaa ttaccaaaat caatcgtaaa aagtctgcaa
     7441 ctggctgaag acaatatcga atcggctgaa ttgatggata agatgatcaa tctccaagtt
     7501 attccaggaa atacggcttt tgtaaaagct cagttaatcg agacttttgc agacaagatt
     7561 tttagctgtt tgactgatga tagctcgatt ttagtcattg ccagaagtgg aagtctagca
     7621 gaggaaatct ttgaacaagt aaaaaattgg taggtctata tgttacttga aatttcgata
     7681 aaaaactttg ccattattga ggctatttcc ctcaattttg aaaaggggat gactgtcctg
     7741 actggtgaaa cgggtgcagg gaagtcgatt atcattgatg ccatgaatat gatgttggga
     7801 gctcgtgcga cgacagatgt tattcgtcat ggtgcaccaa aggcagagat tgaggggctt
     7861 ttctcagttg agaatagtcg tcttttacag gaaatttttg atgagcaagg tttagaatta
     7921 ggtgatgaaa ttatcatccg tcgggaaatc ttgcaaaatg gtcgtagtat cagccgtgta
     7981 aatggtcaga tggttaatct gtctgttttg cgagctattg ggcaacatct tgtagatatt
     8041 catggtcagc atgaccatga ggagttaatg cgtccccaac tgcatatcca gatgttggat
     8101 gaatttggtg atgccgcttt ttgggacttg aaagaaacct atcaaacgag ttttgatgcc
     8161 tatcggaaaa tgcgtaagca ggttctggaa gtcaagaaaa accaacagga acacaaggca
     8221 cgtatcgaaa tgttggaatt tcaaatgaca gagattgagg cagcaaactt gcaggctgga
     8281 gaagacttgg ctctcaatca agaacgagat aaactcctca accacaaaaa tattgcggat
     8341 acactgacca atgcctacag tatgttggac aatgaagatt tttcaagtct ggccaatgtt
     8401 cgttcagcta tgaatgacat ggaaagtgtc gaagagtatg atcctgaata ccgtgaaatt
     8461 tcaagctctc tgtctgagac ctactatgtt ttagaagaca ttagcaaacg tttggaagct
     8521 atcattgagg accttgattt tgatggcaat cgcctcatgc aggttgagaa tcgtttggac
     8581 ctccttcata ctattactcg taagtatggt gggactgttg atgatgtttt gctttatttt
     8641 gccaagatta cggaagaata caatctcttg acaggcaata atctttcgtc tgaggacatg
     8701 gaagcagagc ttaagaagtt ggaagtcaat cttgtcaatt tggcaggtca acttgcttct
     8761 gctcgtcata atttggctca gcaactcgaa gctgagatta aacaagaact gcaagatctt
     8821 tatatggaaa aagcccagtt tcaggttcgt tttagtaagg gaaaattcag tcgtgaggga
     8881 aatgaaatgg ttgagtttta tatttcaacc aaccctggag aagactttaa acccttggtt
     8941 aaggttgctt ctggagggga attatctcgt ctcatgttag ccattaagtc tgccttttca
     9001 cgtaaagaag gcaagactag cattgtcttt gatgaggtgg atacgggagt ttcaggtcgt
     9061 gttgctcaag ctattgctca gaaaattcat aaaattggtc agtatggtca ggttttggct
     9121 atctcccatt tgccacaagt aattgcgatt gcagattatc aattctttat tgagaagatt
     9181 agtaatgacc attcaacggt ttcgactgtt cgtctcttga cagtcgaaga gcgagtggag
     9241 gaagttgcca agatgttggc aggtgatgat gtgacagaag cagccctgac gcaagccaga
     9301 gaattgttga gaaacaggga gaaataagat gacagattat tatgtaattg gagatgttca
     9361 cggaaaagct gggatgctgg aagaccttct taaaacctgg gatggtcaga cccagttgct
     9421 ctttctaggt gatttgattg acagaggtga ggatagtcac cgtgttcttg aaatggtcaa
     9481 ggacttggtg gacaatcaag gggctatctg tttgtctgga aaccacgagt atatgttttt
     9541 gacttggcta gatgacccag aagaaagtta tgaccattat cgtcgcaatg gtggagatac
     9601 aaccattaac tctatcctag gtcgtccctt ggatgcacca gttgatggag tagaagatgc
     9661 caagcgggtt gccgctgaag cggcagactt ggtcgaattc attcgtcaaa tgccatttgt
     9721 agtagagaca gacaagtata tctttgttca cgcaggtatt gatttgacct tggacgactg
     9781 gcatgaaaca acagattata aaaaagtatg gcttagaaaa ccattccacg gagctgaaaa
     9841 tcatactgga aaaaccattg tcttcggtca tacaccggtc tatggtttgt tacagcaaga
     9901 acgcggtaca tctgagcttt ggactacaga agatggcaag attggaatgg atggaggagc
     9961 tgtttatggt ggtgtccttc acgggattgt ctttacagac caaggaatga cagaacacca
    10021 ctttatcgaa aatgacggct ttgtcgctga agattagtac tcttagcagg gtatggtctt
    10081 gtcaaaatat caaaaacaat ttataataaa tagataccct gaaaggaaga gaatcatgaa
    10141 cttagaagaa ttgaaaaaac gacaggagaa gatccgtaac ttctctatta tcgcccatat
    10201 tgaccacgga aaatcaactc tagcagaccg cattttggaa aaaacagaga cggtttcaag
    10261 tcgtgaaatg caggcccagc ttttggatag catggagcta gagcgggaac gtggaattac
    10321 tattaagttg aatgccatcg agttgaatta cactgcaaaa gatggggaaa cttatatttt
    10381 ccacttgatt gacacaccag ggcacgttga ctttacctat gaagtttcac gttcgctagc
    10441 tgcctgtgag ggtgctattt tggtggtcga tgcggctcaa ggaattgagg ctcaaactct
    10501 tgccaacgtt tatctggctt tggataatga tttggaaatc atgcctatca ttaataaaat
    10561 tgacctgccg gctgcagatc cggagcgcgt gcgtacagag attgaagatg tgattggttt
    10621 ggatgccagt gaagcagttt tggcttctgc caaggctggt attgggattg aagaaatcct
    10681 cgagcaaatt gtagaaaaag taccagcacc aacgggtgat gtgacggcgc cacttaaggc
    10741 cttgattttc gactctgttt acgatgctta ccgtggggtt atcctccaag tacgtgtcat
    10801 ggacggagtg gtcaaacctg gtgataagat tcagctcatg agcaatagta agacctttga
    10861 tgtgaccgaa gtcggtattt ttacaccaaa agcggttggt cgtgatttcc ttgcgactgg
    10921 tgatgttggt tacattgcgg cgtctatcaa gacggttcag gatactcgtg tgggtgatac
    10981 cgttaccttg gcaaccaatc ctgcggcaga accattacat ggttataagc agatgaatcc
    11041 tatggtcttt gcgggtctct acccaatcga atcaaacaag tacaatgacc tgcgtgaagc
    11101 gcttgaaaaa ttgcaactga atgatgctag tcttcagttt gaaccagaaa catctcaggc
    11161 acttggattt ggttttcgtt gtggatttct tggacttctc catatggatg tgatccagga
    11221 acgtttagag cgtgagttca atattgacct catcatgaca gctccgtctg ttatttacaa
    11281 agttaatttg accgacggtg agtctatgga tgtgtctaac ccatctgagt ttccagaccc
    11341 aactaagatt gcgaccattg aagagcctta tgtcaaggcg caaatcatgg taccacagga
    11401 gttcgtcgga gcagtaatgg agctagctca gcgtaagcgt ggggactttg tgactatgga
    11461 ctatattgat gataaccgtg tcaatgttat ctatcaaatt cctcttgctg aaattgtctt
    11521 tgacttcttt gataaactta agtcttcgac acgtggttat gcaagctttg actacgaatt
    11581 gtcagaatat cgcccatcta agctggtgaa aatggatatc cttctcaatg gagataaggt
    11641 ggatgccctc agctttatcg ttcacaagga ctttgcctac gaacgtggga aactcatcgt
    11701 tgataaactc aagaaaatca tccctcgcca acaatttgaa gttccaatcc aagcggctat
    11761 tggacacaag attgtcgctc gtactgatat caaggccctt cgtaagaacg tacttgctaa
    11821 atgttatggt ggtgacgttt ctcgtaagcg taaactcctt gaaaaacaaa aagctggtaa
    11881 gaaacgcatg aaatccatcg gatcagttga agttccgcaa gaagccttcc tcagcgtctt
    11941 gagtatggat gaagaataag ttatcagaaa tgcctttcct tgttcacagg aaatttatat
    12001 aagaatcaat agtaaagcag gcttagatgg tctgcttttt tagtttttat actcttcgaa
    12061 aatctcttca aaccacgtca gcgtcgcctt accgta
//
LOCUS       DBEJZJ010000044        11787 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000044 DBEJZJ010000000
VERSION     DBEJZJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.44"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..95
                     /locus_tag="ACL3R8_001754"
     CDS             <1..95
                     /locus_tag="ACL3R8_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR1314591.1"
                     /translation="MFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            111..608
                     /locus_tag="ACL3R8_001755"
                     /pseudo
     CDS             111..608
                     /locus_tag="ACL3R8_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            765..1190
                     /gene="lacA"
                     /locus_tag="ACL3R8_001756"
     CDS             765..1190
                     /gene="lacA"
                     /locus_tag="ACL3R8_001756"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR1314592.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1221..1736
                     /gene="lacB"
                     /locus_tag="ACL3R8_001757"
     CDS             1221..1736
                     /gene="lacB"
                     /locus_tag="ACL3R8_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR1314593.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1747..2676
                     /locus_tag="ACL3R8_001758"
     CDS             1747..2676
                     /locus_tag="ACL3R8_001758"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR1314594.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQDPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2678..3658
                     /gene="lacD"
                     /locus_tag="ACL3R8_001759"
     CDS             2678..3658
                     /gene="lacD"
                     /locus_tag="ACL3R8_001759"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR1314595.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3892..4728
                     /locus_tag="ACL3R8_001760"
     CDS             3892..4728
                     /locus_tag="ACL3R8_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR1314596.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4764..5081
                     /locus_tag="ACL3R8_001761"
     CDS             4764..5081
                     /locus_tag="ACL3R8_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1314597.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5083..6777
                     /locus_tag="ACL3R8_001762"
     CDS             5083..6777
                     /locus_tag="ACL3R8_001762"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR1314598.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVTANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6992..8398
                     /gene="lacG"
                     /locus_tag="ACL3R8_001763"
     CDS             6992..8398
                     /gene="lacG"
                     /locus_tag="ACL3R8_001763"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR1314599.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8441..8692
                     /locus_tag="ACL3R8_001764"
     CDS             8441..8692
                     /locus_tag="ACL3R8_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR1314600.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQMPCLTSEELKSLGKWYVSTGK
                     EWICHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
     gene            complement(8977..9738)
                     /locus_tag="ACL3R8_001765"
     CDS             complement(8977..9738)
                     /locus_tag="ACL3R8_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR1314601.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9920..10882)
                     /gene="nrdF"
                     /locus_tag="ACL3R8_001766"
     CDS             complement(9920..10882)
                     /gene="nrdF"
                     /locus_tag="ACL3R8_001766"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR1314602.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11070..>11787)
                     /locus_tag="ACL3R8_001767"
     CDS             complement(11070..>11787)
                     /locus_tag="ACL3R8_001767"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Catalyzes the rate-limiting step in dNTP synthesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     alpha"
                     /protein_id="HGR1314603.1"
                     /translation="PESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANG
                     SYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQEDGLYHQNRLAVAPNGS
                     ISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDV
                     YAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYV
                     RTFTDDGGEVGANQCESCVI"
BASE COUNT         3691 a         2035 c         2402 g         3659 t
ORIGIN      
        1 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
       61 gtgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aataaagaaa
      121 ctagcaaggt catgccttac tttattggtg gacatccagg atttaattgt cctctacttg
      181 atgatggagt ctatgaagat tattatctag agtctgagaa agaagagact tgctctgttc
      241 cacgtccttt cccagaaaca ggtatgttgg atttccaaga tagaagtcca tggctagagg
      301 gacaaaaaga aatagatctt agttatgatc ttttcagcac agatgcagtg actttggatg
      361 aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc
      421 attttgcaga atttccaaac ctcatcatct ggtcaacttt gaacaaggga cctttcatta
      481 cctttgaacc atggtctggc ttgtcaacat tccttgaaga aggagatcat ttagaagata
      541 agaagaatgt ttgtctctta gaagccaatc aggttgaaga attagggttt gagatagaag
      601 ttttataaaa aagtaaaaaa taaataacaa aaacaaacac aaactattga cttcttcaaa
      661 caatagtagt atattatgtt tgtgaggact aattgactgt tttttaaaga cagccaatac
      721 actgctggaa tccagcatag aaaaaataaa aaggagtata caatatgtct attgttatcg
      781 gtgcagatgc tgcaggtttg agattgaaag aagttgtgaa agacttctta gaaaaagaaa
      841 acttccacct tgtggatgtt acagctgaag gtcaagactt tgttgatgtg actctcgctg
      901 ttgctgcaga agtaaacaaa gaagaacaaa accttggtat cgtgattgat gcttatggag
      961 ctggtccatt tatggttgca actaagatca aaggaatggt tgctgcagaa gtatctgacg
     1021 aacgttcagc ttatatgact cgtggccaca acaactcacg tatgatcact atgggggcac
     1081 aacttgttgg tgatgaattg gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg
     1141 acggtggacg tcatcaaatc cgggttgaca tgttgaacaa aatgggctaa ttagattaca
     1201 gtaagaaagg taagttaaaa atgagaattg caattggatg tgaccacatc gtaactgatg
     1261 aaaaaatggc ggtttcagaa tttttgaaat caaaaggata tgaagtcatt gactttggta
     1321 cctatgacca tacacggact cactacccaa tctttggtaa aaaagtaggg gaagcagtaa
     1381 ctagtggtca agctgatctc ggggtatgta tctgtggtac tggtgttggt atcaacaacg
     1441 ctgtaaataa agttccaggt gttcgttctg ccttggttcg tgatatgaca acagcccttt
     1501 atgctaaaga acaattgaac gccaacgtta tcggttttgg tggtaagatt actggtgaat
     1561 tgcttatgtg tgatatcatc gaagctttca ttcatgctga atacaaacca tctgaagaaa
     1621 acaaaaaatt gattgcgaaa attgaacacc atgaaagtca caatgctcaa caaacagacg
     1681 caaacttctt cactgaattc cttgaaaaat gggatcgcgg agaataccac gactaagagg
     1741 taacctatga ttttaacagt tacaatgaac ccatccattg atatttccta tcccttggat
     1801 gagttgaaga ttgatactgt caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag
     1861 ggactcaatg ttacccgagt actttcagaa tttggtgatt ctgttcttgc tactggttta
     1921 gtgggtggca aacttggtga gtttttggtt gaacatatcg ataatcaagt aaagaaagat
     1981 ttcttctcaa ttcagggaga aactcgtaac tgtatcgcta ttctccacgg agacaaccaa
     2041 acagaagttc ttgaaaaagg tcctgaagta ttggaacagg aaggtcaaga gtttttggaa
     2101 catttcaaaa aactcttgga atcagttgaa gtagtggcca tctcaggtag tctgccagct
     2161 ggccttccag ttgattacta tgcgagcttg gtagaacttg ctaatcaagc tggcaagcct
     2221 gtagtcttgg actgctcagg tgcagcactt caggctgttc ttgaatcacc ccataaacca
     2281 acagtcatca aaccaaataa tgaagaattg tctcagcttc ttggaagaga agtttctgag
     2341 gatttggatg aattaaaaga agtacttcaa gaccctttgt ttgcagggat tgaatggatt
     2401 atcgtttcac ttggtgccaa cggtactttt gccaaacatg gtgacacttt ctacaaggta
     2461 gatattccta gaattcaggt ggtaaatcct gttggatctg gagactctac tgtggcagga
     2521 atttcttcag gacttcttca caaagaatcg gatgcagaat tactcatcaa ggcaaatgtc
     2581 cttggtatgc tcaatgctca agaaaaaatg actggtcatg tcaacatggc caactatcaa
     2641 gttctatatg atcaattaat agtaaaagag gtataaaatg gctttaacag aacaaaaacg
     2701 tgtacgctta gaaaaacttt ctgatgaaaa tggtatcatc tcagctcttg catttgacca
     2761 acgtggtgct ttgaaacgcc tcatggctca acaccaaaca gaagaaccaa ctgtggccca
     2821 aatggaagaa cttaaagtct tggtagcaga tgaattgact aaatacgctt catctatgct
     2881 tcttgaccct gagtatggac ttccagcaac taaagctctt gatgaaaaag ctggtcttct
     2941 ccttgcttat gaaaaaacag gttatgacac aacaagcaca aaacgcttgc cagactgctt
     3001 ggatgtctgg tctgcaaaac gtattaaaga agaaggtgca gatgcagtta aattcttgct
     3061 ttactatgat gtagatagct cagacgaact caatcaagaa aaacaagcct acatcgaacg
     3121 catcggttct gagtgtgtgg ctgaagatat cccattcttc cttgaaatcc ttgcttacga
     3181 tgaaaaaatt gcggatgcag gttctgtaga atacgcgaaa gtaaaaccac acaaagttat
     3241 cggcgctatg aaagtctttt cagacccacg ctttaacatt gatgtcttga aagttgaagt
     3301 tcctgttaac attaaatatg ttgaaggctt cgctgaaggt gaagtagttt atacacgtga
     3361 agaagcagca gccttcttca aagcgcaaga tgaagcaacg aacttgccat acatctactt
     3421 gagtgctggt gtatcagcta aactcttcca agatactctt gtatttgctc atgaatcagg
     3481 tgcaaacttt aacggagttc tttgtggccg tgctacatgg gcaggatcag ttgaagctta
     3541 catcaaagat ggtgaagcag cagctcgcga atggcttcgc acaactggat ttgaaaacat
     3601 tgatgagctc aataaagttc ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga
     3661 aagtcctcct agtttaggaa catgaatcta aaaaaattta aaaaaagttg tatgtaaagg
     3721 tttacaaaat aacttacttg tgctatactt aaatcacaag ttaatacaag gtgagtgtta
     3781 ctaagtaata ttaggcatga tcacaggtga attagaaatc agctgatttt ctagttcatt
     3841 tgtggtcatt ttttgtactt atataccttt aagatataaa aggaggttga catgtatcga
     3901 attctaaatc caatgaatca caatgtctcg cttgtcagaa atgataaggg agaagaggtg
     3961 attgtaattg gtaagggaat tgcattcgga aagaagaagg gggatttgat tgctgaaaat
     4021 caggttgaga aaatctttcg gatgaagacc gaagagtcca gagaaaactt tatggctctt
     4081 ctcaaagatg ttccgcttga ttttatcaca gtgacctatg aaatcattga taagctatca
     4141 aagaaatatc attatccgat tcaagagtat ctctatgtaa ccttgacaga tcatatttac
     4201 tgttcttatc aagctctaac tcaaggaagg tacaaggata gtaatctgcc agatatttcc
     4261 gctaagtatc ctgtcgcttt tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag
     4321 ctagcagatc attttcctga ggacgaaatt attcggattg cttatcattt cattaatgct
     4381 gaaggtgaaa atgaagtgga acttgtggag tcgattgata agaggaaaga aattctcagg
     4441 aatgttgaag aagttttaac ggactatgca attcaacgaa ctaaaaagaa taaccatttc
     4501 tatgatcgct ttatgatcca tttgaattat ttcttggatt atttagacag atctagagat
     4561 gataaccaat cacttctgga tatggaagat catattaaac aatcctatcc aaaagccttc
     4621 gagattggtt ccaagatcta tgatgtgatt acgcaacata cgggtcttga tttgtataaa
     4681 agtgaacgag tttatctagt tctacatatc caacgtttat tgtcataaaa atttatttaa
     4741 aactatataa ggagaattct atcatgaata gagaagaagt aacattgtta ggttttgaaa
     4801 tcgtagccta tgctggcgat gctcgttcaa aactattgga agccttgaag gctgctgaag
     4861 ctggtgattt tgaaaaagcg gacgctctgg tagaggaagc tggtagctgt attgcagagg
     4921 ctcaccacgc gcaaacaagt ctattgacta aggaagcttc tggtgaggac ttagcgtata
     4981 gtgtgaccat gatgcatggt caagatcact tgatgacaac tatcttgtta aaagacctaa
     5041 tgcaccattt aattgaactt tacaagagag gagttaaata aaatggataa gttaataatt
     5101 tttattgaga aaggaaagcc tttctttgag aaattatcga gaaatatata cttaagagcg
     5161 ataaaagatg gttttatttc cagtatgcca gcagtattat tctcaagtat ttttatacta
     5221 atagctgctg tgcccaatat ttttgggttt aaatggtctg atgaacagtt agcttttatt
     5281 ttgaaacctt acaactactc aatggggatt ttagctctct tagtagctgg gacaactgca
     5341 aaatcgttaa cagattcagt taatacacgt agtatggaga aaaccaacca aatcaactac
     5401 atgtcaactt ttttagcagc tgttgttgga ttgttaatac tggcagctga tccaattgaa
     5461 ggtggatttg ctaatggtct tttaggtact agaggattac ttactgcatt tttggcagct
     5521 tttattacag taaatatcta taaagtatgt attaaaaata atgtaaccat tagacttcct
     5581 gaagaggttc caccaaatat tgcacaagtt tttaaagatg ttattccgtt tgccttatct
     5641 gttctttcaa tatatggatt ggatttaatt gttagaaata tttttggtac aaatgtagca
     5701 gaatctgttg gtaaaatatt agcccctcta ttttcagcta ctgatggtta tatcggttta
     5761 gctattgtat ttggtgctta tgctttcttt tggtttgttg gaattcatgg gccatctgtt
     5821 gtagaacctt taattgtagc tatcagttat gcaaatatag aagctaatgt tcagcttgtg
     5881 caagctggta tgcacgcaga taaaatttta aatccagtta ctcaaacttt tgttgtaaca
     5941 atgggtggta ctggtgcaac actagtagtt ccatttatgt ttatgtggtt atgtaaatca
     6001 aaaagaaata gaattgtcgg acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa
     6061 ccaatcctat ttggtgctcc aattgtttta aatcctatct tctttattcc gtttgttact
     6121 gctcctatta tcaatgtttg gattatgaaa ttttttgtag atgttctaca aatgaatagt
     6181 ttcagtatta ttttaccttg gacaacacct gctccaattg gtattgttat gggaacggcg
     6241 ctggctccat tgtcattcgt cttggctata actttaatca ttatcgacac tttaatctat
     6301 tatccatttg ttaaagttta tgaccatcaa attttagaag aagaacggaa aggaaactct
     6361 tcatctgaat tgaaagaaaa agttactgca aacttcaaca ctgcaaaagc ggatgctatt
     6421 cttgaaaaag cgggtgtcga tgcagcacaa aataccatca ctgaagaaac aaatgtcctc
     6481 gttctctgtg caggtggagg tacaagtggt ctccttgcaa atgctttgaa taaggcagca
     6541 gcagaataca atgtccctgt gaaagcagca gcaggcggct atggtgctca ccgtgaaatg
     6601 ttgccagagt ttgatttggt tatccttgct cctcaagttg cttcaaactt tgaagatatg
     6661 aaggcagaaa cagataagct cggtattaaa cttgctaaga cagaaggcgc tcaatacatc
     6721 aaattaactc gtgatggaaa aggtgcccta gcattcgtac aagagcaatt cgattaaggc
     6781 taggaactgt gaaacagtct cccatcgtta cggaaatcgc tatggcgaat ttcctaatcg
     6841 ccttattaat tcgtcggtaa aaagatatcg tttttacctc ctcatgtcac aattcagtga
     6901 cttggtacaa gaagtgagat ggagaagcat ggctcactga ctcctctcct ctcactttta
     6961 ctttatttaa atcaagaaat aggtgaaaaa aatgacaaaa acacttccaa aagactttat
     7021 tttcggtggc gcaacagctg cttatcaagc agaaggtgct acacatactg atggaaaagg
     7081 accagttgct tgggataaat atcttgagga taactactgg tacactgccg aaccagctag
     7141 tgatttttac aatcgatatc cagttgacct caagctagca gaagagtatg gtgtcaatgg
     7201 tattcgaatt tctattgctt ggtcacgtat tttcccgact ggttacggcc aagtaaatgc
     7261 taaaggtgtt gagttttatc ataatttatt tgcagagtgt cataaacgtc atgttgagcc
     7321 ttttgtaact cttcatcact ttgacacgcc agaagctctc cactcaaatg gagacttctt
     7381 aaaccgtgaa aatatcgaac attttgtaga ctacgctgcc ttctgttttg aagaatttcc
     7441 agaagtaaac tattggacaa cctttaatga aattggacca atcggtgatg gtcaatattt
     7501 ggttgggaaa ttccctccag gtatccagta cgaccttgcc aaagtctttc aatcacacca
     7561 caatatgatg gtgtctcatg cacgcgcggt aaaattgtac aaagagaaag gctataaagg
     7621 ggaaattggt gttgttcacg ccctgcctac taaatatcct ctagatcctg aaaatccagc
     7681 agatgttcgt gcagctgagt tggaagatat catccacaat aaattcatct tagacgcaac
     7741 ttatctaggt cgctattcag ctgaaaccat ggaaggtgtc aaccatatct tatcagtcaa
     7801 tggtggtagt ttggatcttc gtgaagaaga ttttacagca ttagaagctg caaaagactt
     7861 gaatgatttc ctaggaatca actactatat gagtgactgg atggaagcct ttgatggaga
     7921 aactgaaatt atccataatg gtaaaggtga aaaaggaagc tctaagtatc aaatcaaagg
     7981 tgttggtcgt cgtgtagctc ctgactatgt accacgcacg gattgggatt ggattatcta
     8041 ccctcaaggt ttgtatgacc aaatcatgcg tgtgaagaaa gattatccta actacaagaa
     8101 gatttacatc actgaaaatg gtctcggcta taaagatgag ttcgttgata acactgttta
     8161 cgatgatggt cgtattgatt acgtgaaaca acacttggag atcttgtctg atgcgattgc
     8221 agatggagct aatgtaaaag gttacttcat ttggtcatta atggatgtct tctcatggtc
     8281 aaacggttat gagaaacgtt atggtctctt ctacgtagat tttgaaactc aagaacgtta
     8341 tcctaagaaa tcagctcact ggtacaagaa agtagcggaa actcagatta tagactagta
     8401 gaattagtca ttagatatag aattttagta agtcaaaaag atgttcaaag attttatcca
     8461 atctatttat gaaaaagttt atattataaa tttcgaaaaa tgctctcaaa tgccgtgttt
     8521 gacgagtgaa gaattgaaaa gtcttggaaa atggtatgtc tcgactggta aagaatggat
     8581 ttgtcattca gatgctgatc tggaagaatt taaaaatcta tttttaaatt ttatcaatcc
     8641 tgaagaatgg gatactatct cctttgattc agattttatg ccgtttcaat aatcgtaacc
     8701 aatttctcaa aaaagttaaa tcttatattt agtactctgt aaaactctta tctaatcacg
     8761 ttgcttatac tcaatgaaaa tcaaagagca actttaaact aggaagcgag tcgcagattt
     8821 ctcaatgtat agctttgagg aattgggcaa aaagtctttg atatagaaaa aagcatagta
     8881 tcaggtgttt caacacctga tactatgctt tttattgtgg gaagatttac tttttttctt
     8941 ctgaaattga gttgttaccc aggctctttc agtttattaa ggcttgatga ctttaatgtg
     9001 tttagatagc ttaaaaagga ttgaatcact tagtttagaa tctgaaacaa tagtatcaag
     9061 atttgatata ttataaaaag tataaaaatc aaacttattg aacttactat gatctgcgag
     9121 taaatatttt ttattagaat tatttaaagc gatgcgttga gcctctccct cttcctcgct
     9181 aaaagtagct agagctccgt tttgaatacc attacagcta acgaaagctt tagaaaattg
     9241 gagattagag agattttgta gggtcaatgt accaacaaaa gcacctgtaa tatcgcgata
     9301 atttccacct attaaaatca aatctgttaa ttttcgttcg cttaaaatca gaaaaacagg
     9361 tagactgttg gttacgacgc ggatattgtc aataggcaac tcacgcgcaa aaaactctaa
     9421 tgttgttcct ggtccaatga aaatagtttc tctttcttct actagactgc ctgcaaaatg
     9481 ggctatttct tgtttttctg ccgtttggag ggcttgtttt tcaatatttg atcgctcatt
     9541 agtcaaaagg gagttggttc gaagtttttc agctccacca tgcacacgaa tcagcaaatc
     9601 tttatcagct aattcctgta aatagcgcct tgcagtcata tctgaaacgg ctatttcgtc
     9661 cataatctgt ttaactgtta tggttccttt actatttact atctctaaaa ttttggttaa
     9721 tttttcttgt ttgagcatat tatcacctcg tttcctacta ctatcttacc ataaacaaac
     9781 tcatcattca aatacaaaaa caacaaaatg aaacaaaaac aaaaatatcg aagtttgttt
     9841 tcaaaacttt cgatattttt gttgggttat aactttgatg tttctagttt actttttgat
     9901 gattgagagt gatggagaat tagtctaaac cgtagttata gtcatcgtct tgcatggctt
     9961 caacttcgcc aagaaggtaa ccatttccga cttgagagaa gaagtcatgg ttggaagttc
    10021 ctgttgaaat accgttcata acgattgggt tgacatcttc agctgaatct gggaaaagtg
    10081 gatcttgtcc catgttcatg agagctttat tggcattgta gcgaaggaag gttttaacct
    10141 cttcagtcca accaacaccg tcataaagac tctctgtgta gccttcttca ttttcataaa
    10201 gagtatagag taggtcgtac atccattctt tgagtttttc ttgctcttct tcaggcaatt
    10261 cattgaaacc aagttggaat ttgtaaccaa tgtaggttcc gtgaacagac tcgtcacgaa
    10321 taatcaattt aatgatttct gcaacgttgg ctagtttgtt gttaccgaga tagtagaggg
    10381 gagtgaagaa accagagtag aagaggaagg tttcgaggaa gacgctggca actttctttt
    10441 caagtgggct gccgtttagg tagatttcgt tgacaatctc agccttcttt tgtaggtaag
    10501 gattggtatt ggtccattcg aaaatttctt caatctcagc cttagtattc aaggtagaaa
    10561 agattgatga gtaagattta gcgtggacag attccataaa ttggatgtta ttgaaaacag
    10621 cttcctcatg tggtgtacgg atgtctgcgc gaagggcttg aaccccagtt tcagattgca
    10681 tagtgtcaag aagggttaaa ccaccaaaaa cttttccgac caagtctttc tctttgttag
    10741 atagctttct ccagtcatcc aagtcgtttg ataagggaat acgtgtatcg agccaaaatt
    10801 gctccgtcag tttttcccaa gttgatttgt cgatgacatc ttcgatggca ttccagttaa
    10861 tggctttgta gtaagtttcc atttaaaatc tctttctgtg tttagtattg cgaactcaca
    10921 attatttcta ctttaccata attctatagg agtatcgcac aaaaagtcgg aagcccgact
    10981 tttaaaatgt tacataaatt atgttatgac atagtagatt tgattttatc agtgctgctt
    11041 agggaaaaat aatgtttcta tgctagaaac taaatcacac agctttcaca ttggttggcg
    11101 ccgacttctc caccgtcatc tgtaaaggta cggacgtagt agatagactt gattcccttg
    11161 ttaaaggcat agttacgaag gatggacaaa tcacgtgtcg tttgtttatt ttccctcttc
    11221 cattcgtaaa ggccttttgg aatgtcactg cgcatgaaga gggtgagtga aagtccttga
    11281 tccacgtgtt cagtcgcagc agcgtaaaca tcgatgactt tacgcatatc catatcgtag
    11341 gcagaagtgt agtaaggaat ggtttctgta gacaagccag cagcagggta gtagatttta
    11401 ccaattttct tctcttggcg ttcttcgata cgttgcgtaa tcgggtggat agaagcagaa
    11461 acgtcgttga tatagctgat agaaccattt ggcgctacag caaggcgatt ttggtggtaa
    11521 agaccatctt cttgaacctt gtcgcgaagt tcagcccaat cagcaacacc agggataaaa
    11581 acatttttga agagttcttt aacacggtct gatgttggaa caaattcacc agttacatac
    11641 ttgtcaaagt aacttccgtt agcatagtct gatttttcaa agttgtggaa ggtaatacca
    11701 cgttcacgcg caatattgtt tgactctacc aaggtccagt agttcataag cataaagtag
    11761 atgcttgtaa attcaacaga ctcaggt
//
LOCUS       DBEJZJ010000045        11545 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000045 DBEJZJ010000000
VERSION     DBEJZJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.45"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="ACL3R8_001768"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="ACL3R8_001768"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR1314604.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="ACL3R8_001769"
     CDS             complement(1165..1689)
                     /locus_tag="ACL3R8_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR1314605.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL3R8_001770"
     CDS             complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL3R8_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR1314606.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RTASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL3R8_001771"
     CDS             complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL3R8_001771"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR1314607.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3156..3559
                     /locus_tag="ACL3R8_001772"
                     /pseudo
     CDS             3156..3559
                     /locus_tag="ACL3R8_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3766..4356
                     /locus_tag="ACL3R8_001773"
     CDS             3766..4356
                     /locus_tag="ACL3R8_001773"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1314608.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4353..5630
                     /locus_tag="ACL3R8_001774"
     CDS             4353..5630
                     /locus_tag="ACL3R8_001774"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR1314609.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5648..6310
                     /gene="deoC"
                     /locus_tag="ACL3R8_001775"
     CDS             5648..6310
                     /gene="deoC"
                     /locus_tag="ACL3R8_001775"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR1314610.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6297..6686
                     /locus_tag="ACL3R8_001776"
     CDS             6297..6686
                     /locus_tag="ACL3R8_001776"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR1314611.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6777..7829
                     /locus_tag="ACL3R8_001777"
     CDS             6777..7829
                     /locus_tag="ACL3R8_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR1314612.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7973..9508
                     /locus_tag="ACL3R8_001778"
     CDS             7973..9508
                     /locus_tag="ACL3R8_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314613.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9501..10559
                     /locus_tag="ACL3R8_001779"
     CDS             9501..10559
                     /locus_tag="ACL3R8_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314614.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFL
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10562..11518
                     /locus_tag="ACL3R8_001780"
     CDS             10562..11518
                     /locus_tag="ACL3R8_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314615.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3287 a         2062 c         2645 g         3551 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttggtctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgt gtgttttgat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt ggtgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcaccgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaagaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgcccatcc caaagaatcc atctgataaa
     1321 ctcccagtca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcaaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg gttaacatcc attcgcagtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg gaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgt
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagtt gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agtacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattact tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgca gatttgtgag attgatactg
     2161 atccagacct gatgggcaaa ggactccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctagg ctcagcatct tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattaa ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttcttttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     3121 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     3181 tggaactctg ttttatttta agttttgctt taccttttat aaaaggaacc aatgcagata
     3241 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     3301 taacagctgt ctttatctgt tcgttcttaa ttgctttctt actaaaaaac gatggacgaa
     3361 atggattgct gcgggtagtt attgcttttt agtcctacgg attgcgacag agggttattt
     3421 cttccacatg tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca
     3481 aacgtatcag ttgggctttt atctaaacat tttgttagga attttgttga taataaagta
     3541 ttttaaggtt aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt
     3601 tttatctgga ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga
     3661 gattgaagaa aatggcttcg tgacttgctt tcttcggtct ttttcgtttt attatcaatt
     3721 tgtaaacgat ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtac
     3781 tatgcagaaa atcctgacgc tgctcacgac attcatgagt tgagagtgga cttgttggga
     3841 gaaaaaatga cttttttgac agatgcgggt gtttttagca agaaaatggt tgactttgga
     3901 agtcaactct tgctcaagtg tctggatgtc aaccaaggag agacagtcct agatgtaggc
     3961 tgtggttatg gtccattagg tttgtccttg gtcaaggttt acggagttca ggcgaccatg
     4021 gttgatatta acactcgtgc cctggattta gctcagagaa atgctgaaaa aaataatgca
     4081 aaagcgacga tatttcaatc taatatttat gcaagagttc aagggcgatt tgaccatgtc
     4141 atttccaatc ctcctatccg tgcgggcaag caagtcgttc atgaaatcat cgagaaaagt
     4201 aaagatttct tggaaattgg tggagatttg accatcgtca tccagaaaaa acaaggagct
     4261 ccaagtgcca aatctaagat ggaagatgtg tttggcaatt gtgaaatcct taaaaaagac
     4321 aagggatact atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa
     4381 aacgagacgg tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtat
     4441 caggaactgt tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa
     4501 tgacgactcg agaaatctct gatttaacga tgaatatggt taagactggg caagagtttg
     4561 acctgtcagc cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata
     4621 aggtaacctt gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga
     4681 gtggtcgtgg tcttggccat acaggcggaa caattgataa attggagtcc attaggggct
     4741 atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg
     4801 tcattgggca atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg
     4861 tgaccgcaac tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg
     4921 cggcaggggc ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga
     4981 cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac
     5041 ggaagacagt agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc
     5101 gtctggaaat ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc
     5161 actttatttg tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg
     5221 aagaagttcg ccaacatctt gaaaatggtc aagcactggc taagtttgag gaaatggtgc
     5281 aagcccaagg tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg
     5341 aaatccctgc tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt
     5401 atgccatgag gctgggtgct ggtcgtgcag ttaagtctga tgtcttggac tatgaaacag
     5461 gaattgtttt tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag
     5521 tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa
     5581 taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa
     5641 aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa
     5701 aaaacaaatt gatagtttgt tgtctgaggc tagagagtat ggctttgcca gtgtttgcgt
     5761 taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg
     5821 cacagtagta ggtttcccct tgggagcaac aacttcaact gtgaaagctt ttgaaacaaa
     5881 agaagctatc caaaatgggg ctgatgagat tgacatggta atcaatgttg gggctctcaa
     5941 gtcaggtgat ttggccttgg ttgagtcgga tattcgtgca gtagtggaag caagtgggga
     6001 caagttagtg aaagttatta ttgaagcttg ccttctgaca gaccaagaaa aagttttggc
     6061 ttgccaatta gcccaaaaag caggagctga ctttgtcaaa acatctactg gcttttcaac
     6121 tggtggtgct acgatagcag atgttagatt aatgcgtgaa acagttggac ctgatatggg
     6181 tgtcaaggcc gccggtggag ctcgttctta tgcagatgct cttacctttg tcgaagcagg
     6241 tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg
     6301 cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt
     6361 ctcactttcc tatcggagca gttttagtag ccaaagacgg aagtgtttac acgggagtga
     6421 atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct atttttaagg
     6481 ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac
     6541 cgatttcacc atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa
     6601 aagtgaccct agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gagttacttc
     6661 catactcttt tacagactta aattagtctg agtcgctctt tgagtggcaa gggtctttgt
     6721 gaccaatcaa tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga
     6781 acaagaaaca atggctaggt cttggcctag ttgcagtggc agcagttgga cttgctgcat
     6841 gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa
     6901 tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt
     6961 tgcaagactg gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat
     7021 caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa
     7081 tctttggtgt tggttttgcc cttcacaatg cagttgaaga agcagctaaa gaacacactg
     7141 acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaaaaatgtt gcgagcgtaa
     7201 ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga
     7261 caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaggcag
     7321 gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtacaagtt gactacgctg
     7381 gttcatttgg tgatgcggct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg
     7441 cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat
     7501 ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc
     7561 aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat
     7621 ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag
     7681 aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag
     7741 taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg
     7801 atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca
     7861 agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag
     7921 acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca
     7981 cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg ttgccaacga
     8041 caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc
     8101 tggtaagtcc acgctaatga acatgttagc aggccttctt gaaccaacca gtggtgaaat
     8161 cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat
     8221 cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat
     8281 tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat
     8341 caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat
     8401 ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat
     8461 ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc
     8521 tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga
     8581 tgaaattcgc gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac
     8641 cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt
     8701 ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga
     8761 tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg
     8821 tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca
     8881 agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat
     8941 tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg
     9001 tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta
     9061 ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc
     9121 taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc
     9181 actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga
     9241 tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca
     9301 caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt
     9361 ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg
     9421 tattgtatca ccagaaacaa ccaataaaca aggacttggt gtcttgatgg ctggtggaaa
     9481 cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt
     9541 ctgtattcct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta
     9601 tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa
     9661 tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag
     9721 ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt
     9781 ggtttgccct gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga
     9841 ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag
     9901 ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg
     9961 cctttatcca tgctttcctt aaagacttca tgcaaagtac agattcgacc attcgtgttg
    10021 gggctaatgc aacctatcag acaccttggt tagctgagtt gactggtaac tcacggatga
    10081 atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa
    10141 caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg
    10201 gtatttctgc caagcggact attatcctat ctatgattat ttcaggtgcc ttggcaggtc
    10261 ttggtggagc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat
    10321 tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta
    10381 tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg
    10441 cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg
    10501 ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa
    10561 gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc
    10621 tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg
    10681 ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc
    10741 agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag
    10801 tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag
    10861 cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta
    10921 taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt
    10981 ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct
    11041 ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg
    11101 tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa
    11161 gatgagatat ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta
    11221 tgcgcaatca atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc
    11281 ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt
    11341 ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt
    11401 gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt
    11461 ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc
    11521 atacaaaaaa acgtcagtcc aatga
//
LOCUS       DBEJZJ010000046        11500 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000046 DBEJZJ010000000
VERSION     DBEJZJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.46"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(80..394)
                     /gene="trxA"
                     /locus_tag="ACL3R8_001781"
     CDS             complement(80..394)
                     /gene="trxA"
                     /locus_tag="ACL3R8_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR1314616.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(411..632)
                     /locus_tag="ACL3R8_001782"
     CDS             complement(411..632)
                     /locus_tag="ACL3R8_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR1314617.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(732..1112)
                     /locus_tag="ACL3R8_001783"
     CDS             complement(732..1112)
                     /locus_tag="ACL3R8_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR1314618.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(1256..2209)
                     /locus_tag="ACL3R8_001784"
     CDS             complement(1256..2209)
                     /locus_tag="ACL3R8_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR1314619.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(2277..3495)
                     /gene="sstT"
                     /locus_tag="ACL3R8_001785"
                     /pseudo
     CDS             complement(2277..3495)
                     /gene="sstT"
                     /locus_tag="ACL3R8_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            3634..4194
                     /locus_tag="ACL3R8_001786"
     CDS             3634..4194
                     /locus_tag="ACL3R8_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR1314620.1"
                     /translation="MQKFIQAYIEKLDVTSIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            4251..5159
                     /locus_tag="ACL3R8_001787"
     CDS             4251..5159
                     /locus_tag="ACL3R8_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR1314621.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5174..5701
                     /locus_tag="ACL3R8_001788"
     CDS             5174..5701
                     /locus_tag="ACL3R8_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR1314622.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            5704..6810
                     /gene="yqeH"
                     /locus_tag="ACL3R8_001789"
     CDS             5704..6810
                     /gene="yqeH"
                     /locus_tag="ACL3R8_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR1314623.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7025..7336
                     /gene="yhbY"
                     /locus_tag="ACL3R8_001790"
     CDS             7025..7336
                     /gene="yhbY"
                     /locus_tag="ACL3R8_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR1314624.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            7388..8017
                     /locus_tag="ACL3R8_001791"
     CDS             7388..8017
                     /locus_tag="ACL3R8_001791"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR1314625.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8017..8610
                     /gene="yqeK"
                     /locus_tag="ACL3R8_001792"
     CDS             8017..8610
                     /gene="yqeK"
                     /locus_tag="ACL3R8_001792"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR1314626.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            8611..9111
                     /locus_tag="ACL3R8_001793"
     CDS             8611..9111
                     /locus_tag="ACL3R8_001793"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR1314627.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            9124..9477
                     /gene="rsfS"
                     /locus_tag="ACL3R8_001794"
     CDS             9124..9477
                     /gene="rsfS"
                     /locus_tag="ACL3R8_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR1314628.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            9586..10326
                     /locus_tag="ACL3R8_001795"
     CDS             9586..10326
                     /locus_tag="ACL3R8_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR1314629.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            10336..11433
                     /locus_tag="ACL3R8_001796"
     CDS             10336..11433
                     /locus_tag="ACL3R8_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR1314630.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHTIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
BASE COUNT         3435 a         2252 c         2630 g         3183 t
ORIGIN      
        1 tatagtctag catatttttt gaaaaatagc aaagggcaag aaaaaagaga ccaaagaaag
       61 tacttggtct ctcgtttgat tagctcaatt cagcaatgat ggccttgatt tgttctgctg
      121 tgtgaacacc tgcaacttgt ttgacaactt ggccgtcttt tttgaagaga agagttggaa
      181 tagacatgat tccaaaagca cgagctgtgt ttggattttc atcaacgtcc attttaacga
      241 ttttcaagac atcttctgaa agttcttcag acaatttgtc caagattgga ccttgcatac
      301 gacatggacc acaccaagtt gcccagaagt ctactaagac caaaccgtct tttgtttctt
      361 gttcgaatgt tgcatctgta attgcttttg ccattgtatt tctccttttt ttagttatat
      421 tggcttaaat cttgtttcat gagatagaag aagatatctc cataagtccc atggtagtcc
      481 aaattatgac ccttgtaagt taatttttgg acagggtagt agtctgcgac gccgataagg
      541 caagcttgtt gcgaacgttc aaagtcttca taagactcga aagtcacagt tctttcgttc
      601 ttgctggcat ctatataggt aatttcaatc atatttaaaa ctcctttgtt taatgctaac
      661 tttattttac tccttataaa agagaatgtc aagaaaaatg attgcgcacg caactttttt
      721 taaaaatcat cttaaatcaa gaaatccaaa cctgcttcca agctttcttc gacagttttt
      781 tgtagcgagg ccagtgtctt ttgcccatca tttgtcaggc agataaaact agagcgtcta
      841 tcttgatggc aacacatgcg actgagtaga ccgcaatttt tagcttccaa gcgagccacc
      901 atcctagaaa ctgcgctcgg gctcagatga agtttatctg gcaggtcaat ctggcgtaga
      961 gatttttctt cagccaagtc cagatagtag agcaggtaga actctttcaa ggtcagactt
     1021 tgctcgctct gttgggcaat ggtctcttcc aagagacttt caatttcttt ctgacgccga
     1081 ttgaagtcaa accatttttc caaataggtc atagtgtctc ctttcttttt agagtcataa
     1141 tatagaagaa agtccattaa cgggcagtct ctgcgtcaca agatgattgc gcatgcaata
     1201 attatactac ttttcaagaa tgctggcaag ctctgttttt tagtggtttt cttttttact
     1261 gtccatattt ttggtaaaaa tcaactttta cttggatgaa ggttttggct tcacgtagga
     1321 gttgaagaag agtggcgcgg gtttcaaact cttctcttgt cttgggcaga ctgcggttcc
     1381 ggaagacttc cagataacgt tcaatttcat ctagcaaatc agaagcagga ttggtctggc
     1441 tcagttgacc tgcaattttt gaaaagagtt gcgctaagat caggctttca ctggcggcaa
     1501 ggtgacaagt gttaatctgt tgggccatgt ttctcaggat acgactttgt cgctgtctca
     1561 tctcaaagta gtggatatgg tagtcggtct ggtgaaagag gtggtcagag tgatccaaat
     1621 agaccagtct gagggcttct ttcaaaagcg tgtctaattc tgctaccagc tgtgctcggt
     1681 tgcgtccgtc tcctctggat aaatagtatt tgaagcgctg gaggatatct tttaactttt
     1741 cttccaccag cgtgtggtag tgctggattt tctcttctcg tgaaggcata tagagattaa
     1801 caagcaaggc aaatcctgta ccaatagcaa agagaaggaa ttcattgact agaaggtctg
     1861 gagaggttga ctcttgaacc aagagatggc taaccaaaac agtgcttggt gtgatgccaa
     1921 tttcccagcc catcttgtag gctaaaggaa cgtagaaggc cagatagagg ccgagactcc
     1981 agatatgaaa tccgctcaag tgaaaagcta gaacaccgat agccagagct agaagcatag
     2041 aaaaaagacg attgcgagcc agttttaaag tacttctacg cgtatcagat aggctcaaga
     2101 gagcgataat tccagccgaa actgctgacg aaagattgag aaaataagca agcaggcagg
     2161 caagacaggt agctaagatg agcttggtcg tacgttggct aatagacata agaatttcct
     2221 aataagttag aataaaagcg taaaagacaa gacatgagca ggcttgcctt gatgagttat
     2281 tttttacggg ttgctgcgta ttcggcaacg gcggtaaaga ggacatctgt agaagagtta
     2341 agggctgttt cacatgagtc ttggatgaca ccaatcacaa aaccaacccc aacaacttgt
     2401 atggcaatat cgttagaaat accgaaaagg ctacaagcaa ctgggataag aaggagggaa
     2461 cctccggcaa tacctgaagc accacaggct gagatagctg ctaccacact gaggacaaag
     2521 gctgtggcaa agtcaacagg aattccaaga gtgttaactg taacaagggt caaaacgtta
     2581 atggtaatcg ctactccagc catattgata gtagaaccga gtgggataga aacagaatag
     2641 gtatctgggt tgagtccaag gtcatggcag agtttcatgt tgacaggaat gttagtcgca
     2701 gaactacgag tgaaaaaggc tgtcacaccg ctgacacgga ggcagttcca aactagagag
     2761 taaggattgc gtctcataaa gaagaaggca atcaaagggt tgaccacagg ggcaacaaaa
     2821 agcatagtcg ttactaatgg aaccaataaa ataccgtagt tggcaaggct tccgactccc
     2881 ttgtcagaaa tggttttaaa aacaagacca aggattccaa atggagccag attgatgatc
     2941 cattcgacaa ttttagaagt cacgtcagcg atagttttta gcaattcttt actattttta
     3001 ctggttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga taagattcca
     3061 atatagttag cagtaagcag ggcgttgact gggctgtcaa ccagtttgag caagaggttg
     3121 ctgaggacct gcccaatccc atctggtggt gcaatttcag tattagcact atttagggta
     3181 atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcgtc gaaagtctct
     3241 atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc ttttgatgtt
     3301 gggaaagggc attggcaacg agggcaaaga ctaggatagg agcaacagct tttagacctc
     3361 caacgaataa atccccgagt agcccaatcc ctgagagatt aggaagggtc agttctagga
     3421 ttccccacaa agcataccaa tcaagatacg cttgacaagg cttgccttat tccaagcatg
     3481 aatgattctt ttcataataa tctccttttt gtgtagtgat tatgattata gtataaatga
     3541 tagacaaaat caagaatttt ctgtctattt tttgaatatt tatggagaat gagactgatg
     3601 aaaatatggt ataatgaaat aaaggagttt tatatgcaaa aatttattca ggcttatatt
     3661 gaaaagctag atgtgacaag cattatcgag aatattctaa ccaaggtcat ttctctttta
     3721 ctgcttttga ttgtatttta tattgctaaa aaaatgcttc ataccatggt gcagagaatt
     3781 gtcaaacctt ctctaaaaat gtctcgtcat gatgtcggac gccaaaaaac catctcacgt
     3841 ttactagaaa atgtgtttaa ttatacgcta tatttctttt tactctactg cattttgtcg
     3901 attttaggtt tgccagtttc tagtttgctg gctggagctg gtattgctgg ggtagcgatt
     3961 ggtatgggag cccaaggctt tctgtctgat gtcattaatg gcttttttat cctctttgaa
     4021 cgtcaactgg atgtgggaga tgaggtcgtt ctgacaaatg gaccgattac tgtatcgggt
     4081 aaggttgtca gtgtgggaat tcgtacgaca cagcttcgta gcgaggagca agcccttcac
     4141 tttgtcccta accgaaatat cacagttgtt agcaatttct cacgcacaga ctagacctgt
     4201 tattttaagt aatttgtggt acaatagagg gagtttaata aggagaaaag atggttttag
     4261 aaaagcagtt gggcaatggt tgtacctgga tagacctaga cctaggaaag ttgaataaac
     4321 tagaagacct ttctgaaatt tacggtttgg acaaggaaac cattgaatac gcactggata
     4381 gaaacgagcg cgcccacatg gactaccacc gtgaaagtgg gacggttacc tttatctata
     4441 atgtcctaga cgtaaaaaag gacaaggcct actatgagac ttttcccatg acctttatcg
     4501 tcgagcatcg tcgcctgatt accattagta ataccaagaa cgcctatgtc attgaacaga
     4561 tgactcgtta tctggagaac catgacacgc tttcgattta taagtttctc tttgccagtc
     4621 tggaaatcat cagcaatgcc tactatcctg tcattgagca gatggacaag agtagggatg
     4681 aggtcaatga cctcttgcgc cagcgaacta ccaagaaaaa cctctttgcc ctgtctgatt
     4741 tggagactgg tatggtttat ctgacggcag ctgccaaaca aaatcggatt ttgttagagc
     4801 atattcaagg tcatgccttg tatcgtagtt ttgatgagat tgagagagaa cagtttgatg
     4861 atgccatgat tgaggctcat cagctggtat ccatgacaga cctaatctct cagattttac
     4921 agcagctttc agcctcttac aacaatattc taaacaataa tctgaatgac aatttgacaa
     4981 ccttgactat catttcagtc ttgctagctg ttttggcagt cgtgacaggc tttttcggaa
     5041 tgaatgttcc cttaccttta acagatgagc cccatgcttg gctctatatc agtttggcta
     5101 gtgcaggttt gtggattgtt ttatccttgt tactaaggaa aattgcgaaa aaaagttaag
     5161 aaaaggagcc agaatggcga ttgaaaatta tataccagat tttgctgtgg aagcagtcta
     5221 tgatctgaca gtcccaagcc tgcaggcgca gggaatcaag gctgttttgg tcgatttgga
     5281 taataccctc attgcttgga acaaccctga tggaacgcca gagatgaagc aatggctaca
     5341 tgaccttcgg gacgcgggta ttggcattat cgtagtgtca aataacacca aaaaacgcgt
     5401 tcaacgagca gttgagaaat ttgggattga ttacgtttac tgggccttga agcccttcac
     5461 atttggtatt gaccgtgcta tgaaggaatt ccactatgac aaaaaggaag tggtcatggt
     5521 tggcgaccag ctcatgacag atatacgagc agcccaccgt gcagggattc ggtcaatttt
     5581 agtcaaaccc ttggtccaac atgactcaat caaaacgcag attaaccgaa ctcgtgagcg
     5641 tcgtgttatg agaaaaatca ctgaaaagta cggaccgatt acatataaaa aaggaattta
     5701 actatggaag aaattctctg tattggttgt ggagcaacca ttcagacgac agataaagct
     5761 ggtcttggtt ttacccccca gtcggcactt gaaaaaggtt tggagactgg cgaagtctat
     5821 tgccaacgct gtttccgtct ccgccactac aatgaaatca cagatgtcca gttgacgaac
     5881 gatgatttcc tcaagctctt gcacgaggtg ggagacagtg atgctttagt ggtcaatgtt
     5941 attgatatct ttgattttaa tggatctgtc atcccaggtt taccacgttt cgtctcgggc
     6001 aatgatgtcc tcttggtagg aaataaaaaa gatatccttc ctaagtcagt taagtctggt
     6061 aagattagcc agtggctcat gaaacgtgcc tatgaagaag gtcttcgtcc agtcgatgtg
     6121 gtcctaactt cagcacaaaa taaacatgcc attaaggaag tcattgacaa gattgaacac
     6181 taccgtaagg gccgcgatgt ctatgtggtc ggtgtgacca acgttggaaa atcaactcta
     6241 atcaatgcta ttatccaaga aatcacgggt gatcagaatg tcatcactac ttcacgcttc
     6301 ccagggacaa ccttggacaa aatagagatt ccgcttgacg acggatctta tatttacgat
     6361 acgccgggaa ttatccaccg ccaccagatg gctcactact tgacggccaa aaacctcaag
     6421 tatgtcagtc ctaaaaagga aatcaagcct aagacctatc agcttaatcc tgagcaaacc
     6481 ctatttttag gtggtttggg acgctttgac tttatagcag gagaaaagca aggatttact
     6541 gctttctttg ataatgaact caaactccat cgtagcaagc ttgaaggagc tagtgctttc
     6601 tacgataagc acctgggaac tcttctgaca ccaccaaata gcaaggaaaa agaagatttc
     6661 ccaaggctag tccagcatgt ctttaccatt aaagataaga cagacctagt catttcaggc
     6721 ctaggctgga ttcgtgtaac aggcatagca aaagtcgccg tctgggcacc agaaggcgtc
     6781 gccgtcgtca cacgaaaagc aattatttaa gcacagaaag gaaagggttg tctgaatttg
     6841 ggcgagcaag gcgagcccca tagagaatac ttttcgctgt ggtgtaagtt ggtacaagtg
     6901 attgtaccaa ctgcggaaaa tttgagacct taggctcaaa ttttagtcat gaaagtccga
     6961 aggactttgc tgacgtccgt caccacttca gaaaagtata aaaagaaact cttttaaaga
     7021 aattatgtca ttaacatcaa aacaacgtgc cttcctcaac agccaggcac acaccctcaa
     7081 acctatcatc caaatcggga aaaatggact caacgaccaa atcaaaacca gcgtccgtca
     7141 agctcttgat gcgcgtgaat taatcaaggt tactctctta caaaacacag atgaaaacat
     7201 ccacgaagta gctgaaattt tggaagaaga aatcggtgtg gatacagtcc aaaaaatagg
     7261 acgcatcttg attttgttta aacaatctag caagaaagaa aatcgcaaga tttctaagaa
     7321 agtcaaagaa atctaagacc gaaactccaa ataactgttt ttatagagaa ataaagggga
     7381 ctagcctatg acaatcgaac tattgactcc ctttaccaag gtagagttgg agccagaaat
     7441 caaggagaaa aaacgcaaac aagttgggat tttagggggg aattttaacc ctgttcacaa
     7501 tgcccatctc attgttgcgg atcaagtacg gcaacagttg ggactggatc aagttcttct
     7561 catgcctgaa taccaacctc ctcacgttga taaaaaggaa accatccctg aacaccatcg
     7621 tctcaagatg cttgagttgg caattgaggg aattgacggc ctagtcattg aaaccattga
     7681 gttggagcgc aagggtattt cctacaccta cgacaccatg aagattttga cagagaagaa
     7741 tccagatacg gattattact ttatcatcgg tgccgacatg gttgactatc tgcctaagtg
     7801 gtaccgaatt gatgaactgg ttgacatggt tcagtttgtg ggggttcagc gtccacgcta
     7861 caaggcaggg acttcctatc cagttatctg ggtggacgta ccgctcatgg atatctcgtc
     7921 cagcatggtg cgggacttca ttgcccaagg tcggaaaccc aactttctcc tacctcagcc
     7981 agtgctagac tacatcgaga aggaggggct ctactgatgt cctatcaaga ctatatcaac
     8041 tgctcccgtg aggccttgtt ggaaaaaatg gcagagcttc tacctgagaa acgtctaacc
     8101 cattgtctag gtgtggagcg tgccgctatg gaattagctc agcgctttgg tgtagatgtt
     8161 gagaaagcaa gtctagcagg tcttcttcat gactatgcta aaaagttgtc agatcaggaa
     8221 tttctagact tgattgaccg ttatcagcta gatttcgacc tcaaaaactg gggtaataat
     8281 gtctggcatg gtatggtcgg aatttacaaa attcaggaag atttggattt gcatgattct
     8341 gaaattctgc gagccattga aattcataca gtcggagctg gtcaaatgac agacctagat
     8401 aaggtcatct acgtcgcaga ctatatcgag cacaatcggg catttcctgg agtggatgtg
     8461 gcgcgtgaga ttgcaagtct atcgctcaat aaggcggtgg cctacgaaac agctcgtacc
     8521 gtggagtatc tagctcatca gggattcccc atctatcccc aaacccttga aacctataac
     8581 gcctttgtgc actatttgaa agaggactaa atgaagacgg cttttataat cattgatgtt
     8641 cagaatgttt tagtagaaac tgggttccag acaaaaagtc tattggaaaa aatttcttat
     8701 ttacaaaacc aggctagaag caagaatatt gaaattatct atgttcaaca tattgagaac
     8761 tctgaagctc aaacatcaga agattggcag ttatctgcgc ttttaaatcg aaaacctgct
     8821 gaaaaggtct ttcagaagaa gtataacagt attttcaaag aaactggctt aaaagaatac
     8881 ttggataagc aggggattga aaaattagtt ttatgtggta tgcagacaga atattgtgtg
     8941 gatacctctg tcaaggttgc ctttgaatat ggctatcagc ttattgttcc agaaggtgct
     9001 gtcacaacct ttgatgggga tgacattcca gcagaaacga ttaatgaatt ttatgaggac
     9061 atttgggagg agcgctttgc agatgttcta gattacaaac atattttcta aaaagaggat
     9121 taaatgaacg aaaaagaatt actagaacta gtcgtgaaag cggctgatga gaaacgtgcg
     9181 gaggatatcc tcgcacttga tgtacaagat ttgactagtg tgacggacta ctttgtcatc
     9241 actagctcaa tgaatagccg tcagttggac gctatcgcag ctaatatccg tgaaaaagta
     9301 gctcaagcag gctttaaagg tagccatgtc gaaggcgatg cagctggagg ctgggtctta
     9361 ctggacctcg gtgctgttgt cgtgcatatc ttttcagaag aaatgcgtgc ccattataat
     9421 ctagagaagc tatggcatga ggcgaattca gtagatattt cagaagctct tgcttagaag
     9481 atgaactcag ttgtagtcaa ctgggtttct ttgcttattt tagaaaaatt gatagaaagg
     9541 taaagggcta gtggtgttta ccatggagct cttagtatca tgattatggc gacttatgaa
     9601 acctttgcgg cggtctatga tgcggtcatg gacgatagtt tatacgacaa atggacgaat
     9661 ttttctctgc gtcatttgcc taagaccaag gagagaaaga aactcttgga attggcttgt
     9721 gggacaggaa ttcaatcagt gcgcttctct caggctggtt ttgatgtgac tggacttgac
     9781 ttgagtgcgg atatgttgaa gattgcggag aagagagcaa cttcagccaa gcaaaagatt
     9841 gcttttatag aaggtaatat gctgaatttg tccaaggcag ggaaatacga ttttgtcacg
     9901 tgttattcgg actctatctg ctatatgcag gatgaggtgg aagtagggga cgtctttaag
     9961 gacgtgtaca atgcgctgaa tgaagaggga gttttcatct ttgacgtgca ctcgacctac
    10021 cagacagatg aagtattccc tggctattcc taccatgaaa atgcggaaga ttttgccatg
    10081 ctttgggata catatgagga cgaagctcct cactccatcg tgcatgagct gactttcttt
    10141 atcaaggagg ctgacggttc ctttagtcgc cacgatgaag tacatgagga gaggacttat
    10201 gagatcttga cctatgatat cttgctggaa caggctggat tcaagtcctt caaactctat
    10261 gcagactttg aggataagga accaacagaa actagcaccc gttggttttt tgtggcgcag
    10321 aagtaggaga acatcatgac catcacaggt attatcgcag agttcaatcc ttttcataat
    10381 ggccataaat acctgctgga tcaggcagag ggactgaaaa ttgttgccat gtcagggaat
    10441 ttcatgcagc gtggagagcc tgctattgtg gataagtgga caagggccca gatggcgctg
    10501 gaaaatggcg cagacttggt agtggaattg ccctttttag tcagtgttca ggcagctgat
    10561 ttctttggtc aaggagctgt ggatatcttg gatcgcttgg gcattgatag tctagttttt
    10621 gggacagagg aagttcgaga ttatcagaaa atcgctgact tatacacaga gaaaggtgct
    10681 gagatggaga aatttgtgga aaatctgcct gattcccttt cctatcccca gaaaacccaa
    10741 tctatgtgga aggaatttgc tggtcttgat ttttcaggta atacccccaa tcatgttctt
    10801 gctctggcct atgcaaaggc ggttgcagga cgaaatatca agctgcatac gattcagcgt
    10861 cagggggcag gttaccattc tgtgaataaa gatgtggact ttgcctcggc gacagccctc
    10921 cgtcaacatc agaaggacca agatttctta gaacgcttta tgccttctgt tgccctattt
    10981 gagcaggcca gtaaggtgat ctgggaagac tattttccct tgctccgcta tcaaatcttg
    11041 tcaaatcccg acctaaccac catctatcag gtcaatcaag aaatggctgt gcgcattaaa
    11101 gaagctatta aaacagccca gtctgtagaa gagttggtcg aggcggttgc gaccaaacgt
    11161 tacaccaagg cgcgtgtcag acgcctattg acctatattt tggtgcaggc tagagaaaat
    11221 gtcttgccag aagccattca tgtccttgga tttactgaaa aaggcaggca acatctcaag
    11281 tctctgaaag gacaggtcaa tctagtcagc cgaattggca aagaaccttg ggatgctatg
    11341 acccaaaaag cagaccagat ttaccaacta ggaaagccaa gtatagcaga gcaaaatttt
    11401 ggaagagtgc cgattagaat agaaacaagc taagtctacc gaaaggtagg ctttttgaga
    11461 ttttttacga ataatactct tcgaaaatca aattcaaatc
//
LOCUS       DBEJZJ010000047        11107 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000047 DBEJZJ010000000
VERSION     DBEJZJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.47"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..608)
                     /locus_tag="ACL3R8_001797"
     CDS             complement(<1..608)
                     /locus_tag="ACL3R8_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR1314631.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRW"
     gene            1205..1786
                     /locus_tag="ACL3R8_001798"
                     /pseudo
     CDS             1205..1786
                     /locus_tag="ACL3R8_001798"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            1783..2973
                     /locus_tag="ACL3R8_001799"
     CDS             1783..2973
                     /locus_tag="ACL3R8_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR1314632.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3483..4475)
                     /locus_tag="ACL3R8_001800"
     CDS             complement(3483..4475)
                     /locus_tag="ACL3R8_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1314633.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4635..6389
                     /locus_tag="ACL3R8_001801"
     CDS             4635..6389
                     /locus_tag="ACL3R8_001801"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314634.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6373..8094
                     /locus_tag="ACL3R8_001802"
     CDS             6373..8094
                     /locus_tag="ACL3R8_001802"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314635.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8105..8689
                     /locus_tag="ACL3R8_001803"
     CDS             8105..8689
                     /locus_tag="ACL3R8_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR1314636.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            8689..9384
                     /locus_tag="ACL3R8_001804"
     CDS             8689..9384
                     /locus_tag="ACL3R8_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR1314637.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            9372..10736
                     /locus_tag="ACL3R8_001805"
     CDS             9372..10736
                     /locus_tag="ACL3R8_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314638.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4072 a         1549 c         1888 g         3598 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact catgtggttt
       61 gaaagagtac aacgtccaga gtatgaaata cacatagctc catggacaaa ggcttcaatt
      121 tcaacatctg tacgtttgcg gatttcagct aattcttcca ttgaaacctc acgcgctaaa
      181 acgacacgag tcaagcctag ctctttccag aactcaaggg tttcatagtt agtggcactg
      241 gcttgggtag aaaggtggat ttcaaggcct ggtgcttcag tagctgcaat cataatcaag
      301 gctgggtcag atacgataac tgctgcaatc ccgatatcac gcagtttacg gaaccactca
      361 ccagcaccag cttcatttcc ttcgtgcata accatattag ccgctacata gaccttggca
      421 ccatacttgg ccgcaaactg cacgccttct tccatctgtt cgaaagtaaa gtttccggca
      481 cggctacgaa gaccataggc ctgaccaccg ataaagacag catctgctcc atactgaaca
      541 gctaccttta gcttctctaa agtccctgca ggtgataaaa cctcaggacg ttttaatgtt
      601 tttgtcataa tttctcctat ttgcaatata aaagtttgac atttttcctt ctcattttat
      661 agtaaataaa ggataaaatc aagcctagac ggattgtttt gacaattcta atcttttaga
      721 ctttgcataa taactgttaa acagtcgaaa attatcccag ttttaacaag tagtcaaaaa
      781 gtctagaaaa gtaaaaacca gtatccaaag atactgactc gtaaaaatac ataaattagt
      841 ccttagatga ctactcccac tctgttgctc ctataatgga aaaggattga tacagtctag
      901 aatatcgctt ttttatttat tattctgata taaaactgtt agaattgatt ttttgtttta
      961 tacccaaata tgaatagaga cgtagctaat aagttgaata acatatttgg aaaaatgaga
     1021 aatagcaata ttactagaac ttttagaaac aatcaatatt taaaaagaaa aaagctcaaa
     1081 gaatttatta aaccatgtta taatagatat agctataatt ttatttataa caagaggata
     1141 gaaatgaccg aattagaaag aaaaaatcga aaaattagct aagaaatatt ctgataactt
     1201 aaacatcaaa gttcaagaga gagttcgtga aatggcaaat gataataaga gccattattt
     1261 gatatacaga gttttaggta tttcatttga agaaggagaa aatatcgatt tgtatcaaaa
     1321 taaaggtcgt tttttataca aatatgctgg ttcattttta gaagaagctg cagtactatc
     1381 ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt aacattccta attctgaaag
     1441 tacaaaacct aagacttttg aaattgattg tttagtcgga gaaaaacacg catacgaaat
     1501 aaaatggtgg gatgcaacta cagatggaga ccatataact aaagaacaca ctagaataaa
     1561 agttattcat aacaaaggat atataccaat tcggttaatg ttctactatc caaatagaac
     1621 tcaagctata aaaattcagc aaactttaga aacattgtat aacggtattg gagggaaata
     1681 ttatggagat tctgcctggg aacatttaag agcagtgacc ggtattgatt tacttagtat
     1741 tctaacagat attgcaaata aaaaaacagg ggtaaaatca aaatgacagt attaaaagga
     1801 gataacttag aaatattaaa aactattgaa tcctcaagta ttgatttaat ctatatggac
     1861 cctcctttct ttacacagaa aacccaaaaa ttatctaata acaaaaatat tatgtattca
     1921 ttcgaagata cgtggacttc gattgaggat tacaaagaat ttttgtctgt aagattagaa
     1981 gaatgcaaaa gagtgctaaa aaatagtggc agtattttcg ttcattgtga taaaattgca
     2041 aatcatcata ttagattaat tttagataat atctttggag cagatatgtt tcaaagcgaa
     2101 attatatgga actataagcg gtggtctaat tcaaaaaagg gattattgaa caatcatcaa
     2161 aacatttact tttattcaaa gtcaaaagat tttaaattta atacaatttt tacagagtat
     2221 tcttctacta caaatatcga ccaaatacta gtggaacgaa aacgagatgg aaactctaaa
     2281 actatatata aagttgataa taatggtaac tatattctag caaaagagaa aaatggagtt
     2341 cccctttcag atgtttggaa tataccattt cttaatccaa aagctaaaga aagagtaggt
     2401 tatcctacac aaaaacctat tctgttatta gaacaaatta taaagattgc tactgataaa
     2461 aatgatatag ttttagaccc gttctgtgga agtggaacta ctttagtagc ctccaagatt
     2521 ttgaatagaa attatatggg gattgattta tctgaggaag ctatcaatat aactcagcaa
     2581 cgtctggaaa atgttataaa aacaagttca aatttattga ataaaggaat cgaagcatat
     2641 agaaccaaaa ctgaggaaga ggaaaacatt cttaaattat tacaggcaaa aattgttcaa
     2701 agaaataaag gaattgatgg ttttttacct aaacattttc aaaaaaaacc gatacctata
     2761 aaaattcaaa aaaataatga atgtctgaat gagagtatct ctttattaca gaatgctata
     2821 aactccaaaa aacttgattt tggagtagtt ataaaaactc attcagataa tttattattt
     2881 gattttgata cgattcctga aaatataata gtagttgacc attttgaact tacaatcgaa
     2941 aaatggttaa gtaaaagtca acagttacta tagtttgcaa attatttaca gaaagaacaa
     3001 aaaatgctct gaaacactga tttcaaagca ttttttgtta gtttaaaatt actcccattc
     3061 ttcttttcca aacgtacaat atatccaaaa ccattcaaaa tactagattc tattttttat
     3121 aatatcacta aatccaccta attataggac gttttcagat ttttagtccc agtcccagta
     3181 ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct taaaagcaaa
     3241 agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa taaaaagctt
     3301 taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg cagagagata
     3361 aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat caaatttatt
     3421 cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg taaaaaatta
     3481 ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt acggacttca
     3541 cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc agatgaatat
     3601 ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag agtttcagct
     3661 acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt ttccttaaat
     3721 aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc ttgatttaca
     3781 ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt atcatcatca
     3841 atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact tatccattca
     3901 tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca atttaatatt
     3961 tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg aagcaaggtt
     4021 gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat tagctctttt
     4081 ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa aacaaaatca
     4141 tcttttatat tatcaaaatc aaaagtacat agagagtttg cggtaatagt ttgatacgga
     4201 ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac atagtctgac
     4261 atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg tatatcgata
     4321 atgaagctgc ctccttcata aaaccaatat agtccttctg cataagttga attctctttt
     4381 ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca ttcatctact
     4441 ttcatataat cttttacaaa atcataatat gacataacac actatccctt ttagacaata
     4501 ttccaattag ccttattaat tcaaaactat tgtattagta attataacag atgtataata
     4561 gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg atattaaaga
     4621 aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa gataagaaat
     4681 atcttggggt tttggccata attttttctg ctatatctgc tctacttaca gtatatggat
     4741 attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta tccggtgcag
     4801 agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt tattttgtct
     4861 caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga aaaaggggaa
     4921 tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct ggtcaaataa
     4981 gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagcacac atgattcccg
     5041 atagttctca ggcaataatc acacccgtac ttgtacttgc acttggcttt atagtaagta
     5101 taagggttgg cataattttg cttgctctta ctataattgg tggcttaatt ttaggggcaa
     5161 tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa ctaagtgctg
     5221 aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca aatgtagagt
     5281 cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat gattattccc
     5341 tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg attgcaattt
     5401 taattattcc tatagtttat tttatgacta gcttagctag cgcaaaggtg attttacttg
     5461 agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg agaatgatgt
     5521 ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag gcgctttacg
     5581 aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa aactataata
     5641 tagaatttga gaatgttagc tttgcttata atgataaagc tgtcattgaa aatttatcct
     5701 ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca ggcaaatcaa
     5761 cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata aagataggcg
     5821 ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc tttgtttttc
     5881 aagattcaaa attattcaag aagagcattt atgataatgt agctttagct aataaagatg
     5941 cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta atattagaca
     6001 aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta tccggtggag
     6061 aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt attattatgg
     6121 atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa gcttttaaaa
     6181 atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca attaaagacc
     6241 ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct gacaaagaat
     6301 taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt gcgaatgaat
     6361 ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga tggaggagca
     6421 agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa catgcttcct
     6481 gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa aagcaatggc
     6541 ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct ttctatcgaa
     6601 tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat aaggacagcg
     6661 gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc cgacatttca
     6721 caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc aataccaaag
     6781 gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc gggcaatgtc
     6841 aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat acctttatct
     6901 aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa aaactcagaa
     6961 agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt atcgaaggat
     7021 attaaagatg acttatataa aaaaatggaa gatagtgaga gagtacactt aaaggcggaa
     7081 gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc tcttgctgtt
     7141 gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct ctaccttata
     7201 ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa agagggcttg
     7261 atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca aaatcaagat
     7321 ctacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa agatgttgag
     7381 tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc taagcaggga
     7441 gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt gaaacttata
     7501 tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga tataaaagaa
     7561 atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt ggttctcttt
     7621 aatcaaagcg ttatggaaaa tattagaatc ggaaagcaag atgcaagtga cgaagaggtt
     7681 aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga taaaggtttc
     7741 gatacagtta ttggtgagaa cggagctgag ctatcaggag gagaaagaca aagattatca
     7801 atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat aacagcaagc
     7861 cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt taaagataaa
     7921 actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa gatagtagtt
     7981 cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca aaaatcaaaa
     8041 atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta ttaggaggac
     8101 tacaatggat aataaaaaat taaaagtaaa agatttagta agcatcggtg tttttggcgt
     8161 aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa tattgttctt
     8221 aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat ttatggctaa
     8281 ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg tgatgtttgc
     8341 agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa tagcagaatt
     8401 aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt atgcaatctt
     8461 cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa aatatatgga
     8521 gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt taataactta
     8581 tcctcacatg gctttagtag ccttaggtgc tttcttagga ggaattcttg gagcatatat
     8641 aggcaaggct ctattgaaaa aacactttga aaaagcaggc attgtataat gcctactttt
     8701 tcttcaaatg ctccctttaa tcccaatccg atctctaaga tattagtcgt atttatcaca
     8761 ggcttaactg ttatgcatag cataaacatc cgttttgagc tggcaattgt ttgtcttatt
     8821 ggtattttgc tttatttgaa tggatacaaa aaaacacttt tcaaatggat tatattgtgt
     8881 gggatacttt actccttgcc taattttatg gtgttatctg aattaaaccc tatagttaag
     8941 atgtttttga gtatacctat tgttattaga atgtttattt taccatttat ggcagcaagc
     9001 tttatgataa agacctcgga tgtaggcgca ataatttcat cgatggataa gcttaagatt
     9061 tcaaagaatg tatccatacc tattgcggtt atgtttagat tcttcccatc ttttaaggag
     9121 gagaagaaaa acatcaaaat ggctatgaga gtaagaggga taaattttaa aaacccagtc
     9181 aaatatcttg aatatgtttc tgtgccacta ctcattatat catctaatat atcagatgac
     9241 attgcaaaag cggcagaaac aaaggcaata gaaaatccaa ttgccaagac cagatacatt
     9301 cgcgtaaaga tacagctaat tgattttgtt tatgttttag cggttgttgg acttattgtg
     9361 ggaggcttaa tatggttgaa ataaaaaatt taagtcttga ttatggtgaa gagcatatat
     9421 tagatgatat atcactatcc atagccgagg gagagtgcgt gctatttaca ggaaaaagtg
     9481 gaaatggtaa gtcatcttta ataaattcaa tcaatggact agctgtaagg tatgataacg
     9541 caaagacaaa ggtcgaaata attattgatg gtaagaatat aaaaaatttg gaactttatc
     9601 aaatctcaat gcttgtttca actgtttttc aaaatcctaa gacatatttt tttaatgtca
     9661 atacgacatt agaattatta ttttatttgg aaaatatcgg tcttgcaaga gaagagatgg
     9721 acaggcgttt gaaggatatg cttgagatat tcccgataaa aaatcttttg aacagaaata
     9781 tatttaatct atccggcggt gaaaaacaaa ttctttgcat tgcagcttct tatatagcag
     9841 gtacaaagat tatagttatg gatgagcctt catcgaattt agatattaaa agcataagtg
     9901 ttttggcaaa gatgctaaag atattaaaag agaaaggcat aagcataatt gttgcagagc
     9961 atagaattta ttatttgatg gacatagttg accgtgtatt tttaatagat aaaggaaagc
    10021 ttaaaaaaac ttatactaga agtgaatttt taaagctaga taaaaatgaa ttaaatgctt
    10081 taagtttaag agataaagaa ttaagtaaat taaaagttcc ttatttaaaa gaaggtggag
    10141 agtatcagat aaaaaatctt agctacaaat ttactgatga tgagtgttta agcttaaaag
    10201 atatttcgtt caagcttggg aaaatttatg gcataatagg atccaacgga cgaggaaaat
    10261 caacgctttt aagatgttta ataggtcttg agaaaaaatc aaaagaagaa atttatttta
    10321 agggagagaa gctatctaaa aaagaaagac tcaaaaactc ttcacttgtt atgcaagatg
    10381 taaatcatca attattcaca gatgaagtat tcaacgagct tagattagga gtaaagaatt
    10441 ttgatgaaga aaaggcgaaa atcattttaa aagatttagg cctggacgaa tttattgaaa
    10501 ggcatccgat gagtttatca ggagggcaaa agcaaaggct tgcaatagca tctgttatgt
    10561 gcaagaattc tccatttgtc ttttttgacg aaccttcaag tggtatggat tattccaata
    10621 tgataaaaat atctgaactg attaataagt ataaaaccat ggataaaata atttttattg
    10681 tttcccatga tatagaattt ttaaatgaag tggcagatga aatttttgaa ttgtaaaata
    10741 gagtctgtta aacatgtcta tagaactagt aaattgtcta aaaatttaaa agatactaac
    10801 acatattgat atttattaga aaattaactt caggattttt acagtattta taaactttat
    10861 aatatgtatt tatagtatta ataatttcca tatctttagg gaaattcttt atttacttac
    10921 cataattaaa gagatgagag ataaatatcg gcagtcttcg gactgccttt atttttttac
    10981 ttaatttaat gcagtaaatc atacgattga aaggaatctg cgttatatgc tataattaga
    11041 tggttaatct atacatttag aaaggtaaaa tatagaattg gagaatgata tgggattttc
    11101 atataat
//
LOCUS       DBEJZJ010000048        10669 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000048 DBEJZJ010000000
VERSION     DBEJZJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.48"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            118..895
                     /locus_tag="ACL3R8_001806"
                     /pseudo
     CDS             118..895
                     /locus_tag="ACL3R8_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            897..1079
                     /locus_tag="ACL3R8_001807"
                     /pseudo
     CDS             897..1079
                     /locus_tag="ACL3R8_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1541..1774
                     /locus_tag="ACL3R8_001808"
     CDS             1541..1774
                     /locus_tag="ACL3R8_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR1314639.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPIMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            1774..3108
                     /locus_tag="ACL3R8_001809"
     CDS             1774..3108
                     /locus_tag="ACL3R8_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR1314640.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQERFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            3118..3372
                     /locus_tag="ACL3R8_001810"
     CDS             3118..3372
                     /locus_tag="ACL3R8_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR1314641.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            3468..3863
                     /locus_tag="ACL3R8_001811"
     CDS             3468..3863
                     /locus_tag="ACL3R8_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR1314642.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            4389..4724
                     /locus_tag="ACL3R8_001812"
     CDS             4389..4724
                     /locus_tag="ACL3R8_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314643.1"
                     /translation="MSHQEKLERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDG
                     ICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIK
                     KARKKDGKN"
     gene            4711..5271
                     /locus_tag="ACL3R8_001813"
     CDS             4711..5271
                     /locus_tag="ACL3R8_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR1314644.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            5271..5849
                     /locus_tag="ACL3R8_001814"
     CDS             5271..5849
                     /locus_tag="ACL3R8_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR1314645.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            5842..8493
                     /locus_tag="ACL3R8_001815"
     CDS             5842..8493
                     /locus_tag="ACL3R8_001815"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR1314646.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            8563..9318
                     /locus_tag="ACL3R8_001816"
     CDS             8563..9318
                     /locus_tag="ACL3R8_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR1314647.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            9597..10400
                     /locus_tag="ACL3R8_001817"
     CDS             9597..10400
                     /locus_tag="ACL3R8_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR1314648.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(10516..>10669)
                     /locus_tag="ACL3R8_001818"
     CDS             complement(10516..>10669)
                     /locus_tag="ACL3R8_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR1314649.1"
                     /translation="EMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQY
                     RTKSFG"
BASE COUNT         3213 a         1988 c         2375 g         3093 t
ORIGIN      
        1 tttcatttca ctataaaaaa ggggttctgt attttttaat gttatctaat tagaaaatgc
       61 tttttttgta ggaaatataa tatgataagg tgcaaaaaag aaataaggag tttgtatatg
      121 gctgaacaag acttagctat gcaagtattg caacaagtgg tgaaactacc tgttgttaag
      181 gttgatcgtt cgaaattttt agtggataag ttttccaaag aattgggtcc acaggacatt
      241 cctaccttat tggaacaagg tccagtctct cttatctcaa gaaatcttag atcgagtggc
      301 taatgcctgt attagggata atgttttatt agcgagtggg acttctgttt tggcaggatt
      361 acctggaggg cttgctatgg caattaccat tccagctgat gtggctcaat tttatacttt
      421 ctctctaaaa ttggctcaag aattaggtta tatttatggt tatgaggatc tttgggcttc
      481 acgcgaggag ttgagtgaag atgctcaaaa taccctcttg ctttatctag gcgtcatgtt
      541 gggggtgaat ggaaccgctg ctttgctacg tgctggtggt ataacaattg ccaaacaggt
      601 aatgaaaaca gtgcctaata aagctttaac aaagacgctt tggtacccta ttttgaaaaa
      661 agtcttaaaa atatttggtg tgaatcttac caagggaggg ctggccaaag gaatagggaa
      721 atttattcct atcttgggtg gtatcatttc aggtggttta acctttgcaa ctatgaaacc
      781 gatgggtgaa agcttgcaga aagaattgtc caagctagtt aactatagtg aagttcaata
      841 tcaagaagat gttgaaacaa tccgaaaaga ggctgaaatc atcgaaggag agtaatatgg
      901 gactcataaa aactctagct aaaatttatg gtaattactt tttgaccgtg taaggtgtaa
      961 aagtaatgaa aacgataaag aaagatgata atgccgttgt cggtctgggg aaacttttta
     1021 ttgccgacaa gttaatggat acggctcggt ggctcattaa gccagaggat aaaaaatgaa
     1081 atttttctgg ggacttcttg ccattatttt tatcaaaccg attattggga ttgtgaaatt
     1141 cttttggatg atcatctctt ttacagtcca attgctgttt tacaagatag tgtttaagat
     1201 attggattgg ctctttaaac ttatctagat ggtaatccaa gtcgcagaga actagcagga
     1261 actccactgc tagtttttta ttctctttcc atatggtata atataagcag taaaatcatt
     1321 ttatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgctgta tatatgttac
     1381 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagctgact tcgtcagttc
     1441 tatctacaac ctcaaagcac tgttttgagc aacctgcggc tagcttccta gtttgctctt
     1501 tgattttcat tgagtattag aacatacaat ggaggtcgtc atggacaata tcatcgatgt
     1561 gtcaattcct gttgcagaag tggtggacaa gcatccagaa gtcttggaaa ttctagtgga
     1621 gttgggtttt aaaccccttg ccaatcccat aatgcgcaat acagttggtc gtaaagtatc
     1681 acttaaacag ggttctaagc tagcaggaac tcctatggac aagattgtac gcacactgga
     1741 agcgaatggc tacgaagtga ttggattaga ctaatgacag atgaacggat tcatatccta
     1801 cgggatattt tgttagaatt gcacaatggc gcctctcctg agtcggttca agagcgcttt
     1861 gatgcgacct ttacgggcgt gtcagccatc gagatttccc ttatggagca cgagctgatg
     1921 aactcggatt cgggcgtcac ttttgaagat gttatggaac tctgtgatgt ccatgccaat
     1981 ctttttaaaa atgctatcaa aggtgtcgaa gttttagata ccgaacaccc tgggcaccca
     2041 gttcgtgtct ttaaggaaga aaatttggcc ctccgtgcag ctttgattcg cattcgtaga
     2101 ttgttagata cctatgagtc tatggaagac gaggaaatgc ttgcggagat gcgcaagggc
     2161 ttggtgcgtc agatgggact tgtggggcaa tttgacatcc attaccaacg taaggaagaa
     2221 ctcttctttc ctatcatgga gcgctatgga cacgattcac ctcccaaagt tatgtgggga
     2281 gtggatgatc agattaggga actctttcaa acagctctaa cgacagccaa gtcactacca
     2341 gaagtgtcaa ttagcagtgt aaaggaagct tttgaagctt ttgcgacaga gtttgaaagt
     2401 atgattttca aggaagagtc catcctcctc atgattctcc ttgagtcttt tactcaggat
     2461 gactggcttc agattgcgga tgagagcgat gcctatggct atgccatcat ccgtccgtca
     2521 gagaaatggg tgccagaacg acagagcttt attgaggaaa agattgcaga ggagcctgta
     2581 cagctagata cggcagaagg tcaagttcaa caagtcatag atacgccaga aggccatttt
     2641 accattacct ttacccctaa ggaaaaggaa gctgtgctgg accgccatag tcaacaggct
     2701 tttggtaatg gctatctttc agtcgagcag gccaatctca tcctcaatca tctccctatg
     2761 gagattacct ttgtcaataa agaagatatt ttccagtatt acaatgacaa tacgccagct
     2821 gatgagatga ttttcaaacg gacgccgtcc caagtcgggc gcaatgtcga actctgtcat
     2881 ccgcctaagt atttggacaa ggtcaaaact atcatgaagg ggcttcgtga ggggaccaag
     2941 gacaagtatg aaatgtggtt caagtctgag tcgcgaggta agtttgtcca catcacctat
     3001 gctgcagtac acgatgaaga cggagaattc caaggagtgt tggagtatgt tcaggatatc
     3061 cagccctacc gtgagattga tacggactat tttcgtggat tagaataagg agaaaaaatg
     3121 agttacgaac aagaatttat gaaggaattt gaagcttggg tcaataccca aatcatgatt
     3181 aacgacatgg cgcacaagga aagtcaaaaa gtttacgaag aagaccagga cgagcgtgcc
     3241 aaagatgcca tgattcgcta cgagagtcgc ttggatgctt atcagttctt gcttggtaag
     3301 tttgaaaact tcaaagcagg caagggattc catgatttgc cagaaggctt gtttggtgag
     3361 cgaaattatt aaacgagaaa gattcttgat ttttcactaa aatcttgata gaatgtttat
     3421 gttaaatcct tgtcagagca gggatttttt attgaaagga ttttatcatg tcaaagaaac
     3481 tcaatcgtaa aaaacaatta cgaaatggcc tccgtcgcgc aggtgccttt tcaagtactg
     3541 tgactaaggt tgtagatgag acaaaaaaag tcgtgaagcg tgcagaacag tcagcaagcg
     3601 cagctggtaa ggctgtttct aaaaaagttg aacaagcagt agaagctacc aaagagcaag
     3661 ctcaaaaagt agctaattct gtagaagatt ttgcagcaaa cttgggtgga cttccacttg
     3721 atcgtgccaa aactttctat gatgaaggaa tcaagtctgc ttcagatttc aaaaactgga
     3781 ctgaaaaaga actccttgcc ttgaaaggaa tcggcccagc taccatcaag aaattgaaag
     3841 aaaatggcat caagttcaag taatttttct tgagccttgc atttccgaga aaaacttgct
     3901 acaatagagc cattagaggt gttttgaatc ccacatttta cagaaagtgg cggcgctgag
     3961 aagtccacaa atgtgtcaaa actggttgct aatgactgaa aaaatgaaat atttctgtct
     4021 ttttatttta aagactaaag atgcgggctt ggcccgaaat tgggtggtac cgcggataaa
     4081 cacattcgtc cctgtcatgt agatggcagg gcttttcttt tgtgtcttag tcaaaggagg
     4141 ttgttataaa acaatcattt aaaactaata aactatatta tggttttcct gtttttattt
     4201 taggatatca agattagaat tttggctata acatcacgac ctgtagttcc tcttatagtc
     4261 taggagattg ggttgtgatt ggagtcgttg cgagagagaa tgccgcagag cagatcaaac
     4321 agtatcaaaa atttactgtg aatatttctg atgaaacttc tatgcttgcg atggagtagg
     4381 ctggttttat cagtcatcag gagaaattgg aacgtttggg agtgcattat gaaatttctg
     4441 aacgaactca gattcctatt ttagacgcct gtccacttgt tttagattgt cgggtagata
     4501 ggattgttga ggaagacggt atttgccaca tctttgccaa gattcttgag cgacttgttg
     4561 ccccagaact cctggatgaa aagggacatt ttaaaaatca actgtttgcc ccaacctatt
     4621 tcatgggaga tggatatcag cgcgtttatc gctatctgga caagcgtgta gatatgaagg
     4681 gcagtttcat caaaaaagcg aggaagaagg atggcaagaa ctgagctgcc agataaaatc
     4741 gaaacagaac gtctcgtttt acgagtccgt actgtggcgg atgctgagga tatctttgac
     4801 tatgctagtt tgccagaggt cgcctatcca gcaggttttc ctccagtcaa gaccttggaa
     4861 gatgagattt attatctgga gcacattctt ccggagcgta atcaaaagga aaatctccca
     4921 gcaggctacg ggattgtcgt caaaggaacg gataagatcg ttggctctat ctatttcaac
     4981 catcgccatg aagatgatgt gatggaaatc ggctatacct tacactcaga ctattggggg
     5041 cgaggttatg tgccagaagc tgcgcgtgcc ttgattgact tagcctttaa agatttgggt
     5101 cttcacaaga ttgaactaac ttgctttgga tataaccttc aaagtcaacg agtcgcggaa
     5161 aagcttggct ttaccctcga agctcgcata agagaccgta aagatgctca aggcaactgc
     5221 tgtgatgatt tgagatatgc cttgctgaag agtgagtggg aggtgatttg atgcatcttt
     5281 tcatcattgg tgctccagca tcaggaaaaa tgaccattgg tcaagaatta tctcgactga
     5341 cggatgctac cctattttat aaccatcaag ccattgattt tgcactagaa atctatcagg
     5401 actatacaga ggaaatgtgg gaatttgttc gtggaatcac tttttcattc cttggagcaa
     5461 gtgcaagaaa tcagcgatca gtaattttaa cagatgtaat tgatttttca aatcagtatc
     5521 agctgatgta tttaaagcaa attcagaatt tgttggatga ttatcatcaa gagattcttt
     5581 ttgttgagtt ggaaacaagt cttgaagagt gcatacgtcg aaatcgaacg gagaatcgat
     5641 taaagcacaa acccttaaaa cgacatattg aggtatctga aagagaaatt ttagagaccg
     5701 ctgaaacact tcaattaaat tcccaatatc aaccgaatga gttgcaccac tactttaaaa
     5761 taaataatac gaatttgtct gcagaagaag ctgctaagca aattcaaaat aaaataaaca
     5821 aaatagagaa aggacacaca catgtctaaa gaactttcat ctaaatacaa tccagccgag
     5881 gttgaggctg gtcgttacca aaaatggctt gatgcggatg ttttcaagcc ttcaggcgat
     5941 caaaaggcta agccttattc aatcgtgatt ccaccaccaa acgtaactgg gaaacttcac
     6001 cttggtcacg cttgggatac gactttgcag gatatcatca tccgtcaaaa acgcatgcag
     6061 ggctttgata ccctttggct tccaggtatg gaccacgctg gtattgcgac tcaggctaag
     6121 gttgaggagc gcttacgtgg tgagggtatt acgcgttatg acctaggtcg tgagtctttc
     6181 ttgacgaagg tctgggaatg gaaagacgaa tatgccacta ccatcaagga acaatggggc
     6241 aagatggggc tttctgtaga ctattctcgt gagcgtttca ctcttgacga aggtttgtca
     6301 aaagctgttc gtaaggtctt tgtggacctt tacaagaaag gctggatcta tcgtggtgag
     6361 tttatcatca actgggaccc agcagctcgc acagcccttt ctgatattga ggtgattcac
     6421 aaggatgtag aaggtgcctt ctaccacatg aattacatgc tggaagatgg ttcacgcgcc
     6481 cttgaagttg ctacaactcg tcctgagact atgtttgggg acgttgcggt tgcgattaat
     6541 ccagaagacc cgcgctacaa ggacttgatt ggtaaaaacg tcatccttcc aatcgctaat
     6601 aaactcatcc caatcgttgg agatgagcac gcagatcctg agtttggtac tggtgtcgtg
     6661 aaaatcacac ctgcccacga tccaaatgac ttcttggttg gccaacgtca taacttgcca
     6721 caagtcaacg tcatgaacga cgacggaact atgaatgagc ttgcctttga attttcaggc
     6781 atggatcgtt ttgaagctcg taaggcagtc gttgctaagt tggaagaaat cggtgccctt
     6841 gtcaaaatcg aaaaacgtgt ccattcagtc ggtcactcag aacggacagg tgtcgtagtt
     6901 gagccacgct tgtctactca atggttcgtc aagatggacc aattggctaa gaacgccatt
     6961 gccaaccaag acacagagga caaggtcgaa ttctacccac ctcgtttcaa cgataccttc
     7021 cttcaatgga tggaaaatgt ccacgactgg gttatctctc gtcagctttg gtggggtcac
     7081 caaatccctg cctggtacaa tgctgatggt gaaatgtatg tcggcgaaga agctccagaa
     7141 ggtgacggat ggactcagga cgaagacgtc ttggatactt ggttcagttc tgccctctgg
     7201 ccattttcaa ccatgggctg gcctgaagtc gactcagaag actttaaacg ttatttccca
     7261 acttcaacct tggtaacagg ttacgacatc atcttcttct gggtgtctcg tatgatcttc
     7321 cagtcattgg aattcacagg ccgtcaacca ttccaaaacg tccttatcca cggtctcatt
     7381 cgtgacgagc aaggacgcaa gatgtctaag tctctcggta acgggattga cccaatggat
     7441 gttatcgaga aatacggtgc cgatgccctt cgatggttcc tttcaaacgg ttctgcgcca
     7501 ggacaagacg tgcgtttctc ttatgagaaa atggatgctt catggaactt tattaacaag
     7561 atttggaaca tttctcgcta tatcctcatg aacaatggag gtttgacgct ggatgtggcg
     7621 catgacaatg tcacaaaagt tgcaacaggt gaggctggta atgtgacgga ccgctggatt
     7681 ctccacaatc tcaacgaaac cattgcaaaa gttactgaaa actttgataa gttcgagttt
     7741 ggtgtggctg gtcatatcct ttacaacttc atttgggaag aatttgccaa ctggtatgtt
     7801 gagttgacca aggaagtcct ttatagcgat aacgaagaag agaaagtcat cacacgttct
     7861 gttctactat acactttgga caagatcctt cgtctccttc acccaatcat gccattcgtg
     7921 acagaggaaa tctttggaca aatctcagaa ggttctatcg tgacagctgc atacccaact
     7981 gttaatctag cctttgaaga ccttgcggct cacactggtg tggaaagtct caaagacttg
     8041 attcgtgctg ttcggaatgc gcgtgcggaa gtaaatgtag caccaagcaa gcctatcacc
     8101 atccttgtta agacaagcga tagcgacttg gaagccttct ttaacagcaa tgtcaactat
     8161 atcaaacgct ttacaaatcc agaacacttg gaaatcgcat caaccatccc tgcacctgaa
     8221 ctggctatgt caagcgttat tacaggagcc gaaatcttct tgccactggc cgatctcctc
     8281 aatgttgaag aagaactagc tcgtctcgac aaagaactcg ctaaatggca aaaagaactg
     8341 gacatggttg gtaagaaact ctctaacgaa cgcttcgtcg ccaacgctaa accagaagtt
     8401 gtccaaaaag aaaaagacaa acaagccgac taccaagcca agtatgatgt gaccgtagca
     8461 cgtattgatg agatgaagaa gttggtgaaa taaacacaga aacacggtga tgagccgtgt
     8521 tttttggtat aatgaaatca atatctattg atggagaaag tgatgtccaa acaccctcat
     8581 tatgaattgt taaatttaat tggctacggt cttgccaagt ttgacaagct ttttataaaa
     8641 gaatttcaat gctctagcaa gtcggagttt tatcgctatg tggtttctct gggaattgct
     8701 gaaacaactg gagttgtaaa aaatagaatg gatttatttg atccttattt tgacaataat
     8761 cgaaaaggtt ggtggcagaa agctgaagtt tatcgttttc gtaaagattt aattgatatg
     8821 atgtttggaa atgaagatgt tcatagttat gctgaaatag ttaaaatgtt acttgccagt
     8881 gaagggaaga aaacaggcat aaccatcgtt gaaaaaccaa tagttcgaac taaattcaaa
     8941 cgtctacagg aaacgggaat ggaggctgag aattatttta tccttcattt tgataaagaa
     9001 gaaaaattcc aaggtggaca gttaaccgat gcccgtcttt atggtgatgg atatgacttt
     9061 caggtagatg tccaagagta ttcttacctt gccgaagtaa aaggtatccg aaaatctaag
     9121 gggcgtgtgc gtttaactgc aaaagaattt gaaaaagtca aggagtttca atcggatttt
     9181 attttatcct tggtcacaaa tctagatgat attccaaagt tagtgttaat cgataatcct
     9241 ttaaaacatt ttgagtttaa aaagaatatt atcaaaaatg aaatcattga atatagaagc
     9301 gtagaggatt tgtattagtt cccccttaac ttttccagtt gaaggaacga gaagtcttga
     9361 taggtcaacg acttaatgaa ctggaaatca acggtattcg tttgactaag ttttaagatg
     9421 gcgaaatcgg tattgaattt atcagtagtg ctgattataa ctcttttatt atttacatga
     9481 agtatatata tatatatcat agaacctatt gtgaggactt tttatagttt aagccagttt
     9541 ccaaccaatt tcgtgattta ctggtaatga agaaaaacaa ttgaaaggat atttctatgc
     9601 aaccaactta caacattgac aatccaaact tgtcttatga agctaagcgt gatttatggc
     9661 ggataggttt tggtctgcag aaagttgaca atctagtgcc atcagcttat atggaatctt
     9721 tggctgagaa acaggctcgg ggtgaactga cttatgagca ggtttatgag gatgcaacgg
     9781 cttatcacca tactattgat gcaagtacgg aggaggcaga cttggtttct ctacgcattg
     9841 tagaactatt gtctcgaaga ggctttagct tcagtcctgc gaccttactt gctattcata
     9901 aggagttgtt tcaagatata tttgaaccct cgattccggt aggtcaattt cgtcagacta
     9961 atatcacaaa gaatgaacct gttttgaatg gtgaaagtgt tgtgtactct gattactcca
    10021 tgattcaaat gacattggat tatgatttta atcaggaaaa acaagttgca tatgcgacac
    10081 taacccaggc ggatatggtt aaaaaaatcc agcattttat ttcaggaatc tggcagattc
    10141 atccatttcg cgaaggaaac gctcggacag taacggtctt tttgattcag tatcttcgtg
    10201 agtttggttt tgatattgat aatataccat ttcagcaaca ttccaagtat tttcgtgatg
    10261 ccttggtatt agataatgca aagattttac agcgacgtcc tgagttttta acagcttttt
    10321 ttgaaaatct cttgctcggt ggtcaaaatg atttgtcttc agaaaaaatg tatctagatt
    10381 tagacctcga tttttcataa tccaaatact gagtaaacat tgaattttag gaaaaaatga
    10441 agtaaacatt cccacaataa aacgcatagt atcaagtgtt aaaatgtact gccccccaaa
    10501 agttagacaa ttaatttatc cgaaggattt agttctgtat tgcacagggc taagtccttt
    10561 tagttttacc ttaattctct tattgttgta ataatcaata tagtctacaa tggcttgttc
    10621 caattgctta agcgactgaa acgacttctc ataaccgtaa aacatttcc
//
LOCUS       DBEJZJ010000049        10459 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000049 DBEJZJ010000000
VERSION     DBEJZJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.49"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(145..217)
                     /locus_tag="ACL3R8_001819"
     tRNA            complement(145..217)
                     /locus_tag="ACL3R8_001819"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(182..184),aa:Thr,seq:ggt)
     gene            complement(317..826)
                     /locus_tag="ACL3R8_001820"
     CDS             complement(317..826)
                     /locus_tag="ACL3R8_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR1314650.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(824..920)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            949..1380
                     /locus_tag="ACL3R8_001821"
     CDS             949..1380
                     /locus_tag="ACL3R8_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR1314651.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            1462..1839
                     /gene="mscL"
                     /locus_tag="ACL3R8_001822"
     CDS             1462..1839
                     /gene="mscL"
                     /locus_tag="ACL3R8_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR1314652.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(1881..2975)
                     /gene="hemH"
                     /locus_tag="ACL3R8_001823"
     CDS             complement(1881..2975)
                     /gene="hemH"
                     /locus_tag="ACL3R8_001823"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR1314653.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVSISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            3130..4353
                     /gene="pepT"
                     /locus_tag="ACL3R8_001824"
     CDS             3130..4353
                     /gene="pepT"
                     /locus_tag="ACL3R8_001824"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR1314654.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(4389..5039)
                     /locus_tag="ACL3R8_001825"
                     /pseudo
     CDS             complement(4389..5039)
                     /locus_tag="ACL3R8_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            5040..5204
                     /locus_tag="ACL3R8_001826"
                     /pseudo
     CDS             5040..5204
                     /locus_tag="ACL3R8_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(5475..6487)
                     /locus_tag="ACL3R8_001827"
                     /pseudo
     CDS             complement(5475..6487)
                     /locus_tag="ACL3R8_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(6713..9832)
                     /gene="phtE"
                     /locus_tag="ACL3R8_001828"
     CDS             complement(6713..9832)
                     /gene="phtE"
                     /locus_tag="ACL3R8_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR1314655.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(10042..>10459)
                     /locus_tag="ACL3R8_001829"
     CDS             complement(10042..>10459)
                     /locus_tag="ACL3R8_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR1314656.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQLAPIQ"
BASE COUNT         3008 a         2030 c         1792 g         3629 t
ORIGIN      
        1 acctgcggct agtttcctag tttactcttt gattttcatt gagtattagt tttatttaca
       61 caggtgcata agaaatatat tggaaaaatt gggggcagac ataacaaaaa cccttgtaaa
      121 tcaagggctt ttctgtctat ttaatgctaa ttgccgggat tgaaccggcg acctcatcct
      181 taccatggat gcgctctgcc aactgagcta aatcagctta cttaagaagt atactataat
      241 cagaaaaact tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta
      301 cctagcttat cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa
      361 tcgctccaat aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga
      421 atggtaattc tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga
      481 ggattgaaaa gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa tccttgctat
      541 attttgcaaa aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa
      601 agacatctag cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga
      661 tgatgtactt aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat
      721 aagcaccata gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag
      781 cgacgattgc aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg
      841 cggttatccg cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgattcattc
      901 aaccttacta gtatagcaca atagcctgct ttatgctata cttaaagcat gaaaaaacct
      961 attcaaaaat tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact
     1021 ctagtttcga ttctctcacg actagtcatt tatcaactaa gtcatcagga actccttgct
     1081 acggccttgg caaatattat cggtatctta tttgccttta tcacaaatga tacgattgta
     1141 tttaagcaaa aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt
     1201 tctacttttc tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatc
     1261 atagggcaat tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca
     1321 caaatattca ttattatcat caattatatc ttgagcaagg tctatatttt tagaaaataa
     1381 tgctccattt atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg
     1441 aaacattgaa aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat
     1501 gttattgacc ttgctgtcgg tgttgtcatt gcctctgctt ttggtgctat cgttacttca
     1561 cttgtaaacg acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtc
     1621 gaacgtatcg ctcaactttc ttggcatgga gtcggctatg gtaacttttt aagtgctatt
     1681 atcaatttta tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca
     1741 cagaaactga ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac cgaattggaa
     1801 gtccttcaag aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc
     1861 aaagctaaat ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt
     1921 ttgataagat aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca
     1981 aattctggca tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc gtctgaagga
     2041 actaactcat caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg
     2101 actctaactg tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga
     2161 cgatggtagt ttaccccaaa ttcctggcat aagtcataac attctacatc attgtcaaac
     2221 aagacctcaa tatgctcact gatgaaacta atagatacaa aaatataatg gtctggatgt
     2281 tctgtctgtt ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca
     2341 ctctcactct gccaagtgtt ggtatattgt tctgaactca agcccagttt ttcagcgact
     2401 agcttgctat tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaatg
     2461 ggcacactat gggctgaaaa gatgacttta aagctgtctt gctttacttc ttcttttaaa
     2521 atcttagcaa tttcatctgc ccaatagttt aagagcgctt cttcctgata ccagtcctta
     2581 atgaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag
     2641 aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt
     2701 tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat
     2761 tcattcccca gcctagcttc taccaaggca acctcttgac gggtaatttt ttgcagaggc
     2821 gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc
     2881 accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt
     2941 gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat
     3001 caagtttatt ttatcattaa ttcatcgata agtaaacgct aacataggga cattctcaat
     3061 cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg
     3121 agttttttta tgacttatcc aaatctcttg gaccgcttct taacctacgt taaggtcaac
     3181 acgcgctctg atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca
     3241 acaaatgtcc taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg
     3301 aatggttttg ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt
     3361 tttatatcgc acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt
     3421 gaaaactacg atggtggtgt gattgaacta gggaattctg gtttcaaact cgatccagct
     3481 gacttcaaga gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaagc
     3541 ttgctaggtg ctgatgacaa gtcaggaatt gctgaaatta tgacaaccat tgaatatcta
     3601 actgctcatc ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa
     3661 atcggtgttg gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact
     3721 gttgatggtg gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa
     3781 ttgcatttcc aaggccgtaa tgtccaccct ggtactgcca aagggcagat ggtcaatgcc
     3841 cttcagctag caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact
     3901 gaaggttacc aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggtgcgt
     3961 gcaagctaca tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg
     4021 caatctatcg ctgataagat gaatgaagaa cttgggagcg accgtgtcac tctcaacttg
     4081 acagaccagt actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt
     4141 gctaaagccg ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccggggtgga
     4201 acagacggct ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc
     4261 gaaaatatgc acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat
     4321 accatcattg gcatcgtagc ttataaaggc taaaaagacg aggtagctca gctacttcgc
     4381 ctttcttttt attctactgg tttttcttga tttccagtag ttgtagaaga ttctgttgtt
     4441 tcattttctg aagttgattc agcaggttta gaatctcttg tattgcttgg tttgttttcg
     4501 tcgctagcag tttcaatgtt agattctgca gttgcgtttg gttggttctc agcactggtg
     4561 ttatcactat ttgcttcagc atttcttgct ggacttgttt cttcacttgc gctagctttt
     4621 gactggattt gatgattcaa aactagaata gcttttgtcg attcaagtaa agctgttttg
     4681 tctttactct tagcagaaag ttgatctaat aatgcatcca ccttatcaaa gtccgcatca
     4741 gatccattat tactttctaa ataagagtga agcgacatga gaatatcgta gagtttttga
     4801 tagagtacaa gtgtctgaga atcttgctca gcattttcct tttcttgttg aagggcgcta
     4861 gcgatacgag tcaaaacatc ttttacctga ctgtttactt catccaagtc tgcatcagcc
     4921 ttgtttgtgg cagcttttag attttctact tcttctgcca aggattgtct gattccttct
     4981 tcatggattt gttccaagag ttgatttgca ttgttcaaaa gactttctac ttcttccttt
     5041 ctatctgtcg cagattattg gttgctatct accatgtact cctaaaacag gagagttata
     5101 atccaagatt acaaggcctt acagaaataa gaaatccaga taagacaatg ttcgtccaag
     5161 acgctattcg cttcgcacag cagcacagat tcaatatact ttaattttaa agtttaggtg
     5221 tcaagacctc tttttagtgt gcccaaaatt tagagaagta atcaatcaac taacttttat
     5281 ttttttcaaa ctttcagtaa actgacctaa agctaactca atctgtcttt gtagatgctt
     5341 ctgctatcag ctagaagttg atctactttt gccaagactg ccttctcatc aaaagttcca
     5401 ggttgatagt tggattgcag ggatggaatc ttgtttttca aagccgcttc atatccctta
     5461 gtttgaacct tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc ttctgaatct
     5521 tcacttataa ttcgattggc atcaaaaacc atgaccatct tcttcctcat ggtggacatg
     5581 tagtgacgga ttacttaata cagaactaga agaacttcct acctcttccg tgttagagtg
     5641 tgatggggga ttgttaagag atgacttagg aatatagtga tagtgttccc catgtcttac
     5701 tatataagca tcacctatat ctctgacaat atcattaggg ttaaagacat atgtggctgc
     5761 taattcacct gccgacaagt cactctcagg aatgaaatga tagtgaccac catgtggtac
     5821 tatagtaggt tgaaatagaa tatgagcaaa ttgataaggg gattttaaag taatttctaa
     5881 caatgattta gaaactatga tgtgctattc taaattcaac tcactatata taaccatcat
     5941 cggtagtata acgtccctgt aattttgcta cagatacttc tgcactagct cctttatcgt
     6001 ctttaccatg ttcttgtttt tggcgattga tttcatcttt tgttcgtaca ttttctgcat
     6061 gagcttgatc tttaaggtaa acataatact ttccatctac cttaataata tatcctccct
     6121 taacctaact gacgatatct tgatctttcg gctgatagtt gggggctttc attagtagct
     6181 cttcactaaa gagcgcatca aaaggaactt taccattata gtagtgataa tgatcgccat
     6241 gagaagttac ataaccttga tctgtaatct taataacaat ttgttttgct tgaattcctt
     6301 ctttttgact aacctagtct ggagtcaaat tttcagtctt cttagtgtct ttattactgt
     6361 ttacatatga aacacgattt ttatctgtat tggcctgtta gctatgttgg ttcagagcat
     6421 aaacacacag acttaaggaa aggataacaa cagatccagc tgctatatat ttctttttaa
     6481 atttcataat tacctcattt ctataattat ttatatgatg tcttcattat taaatgatta
     6541 aataaattaa ttaaccagtt aattaactag tgaatattcc acctcttttt aagttgtatg
     6601 tcaagaaatt ttatatatta ataataaaat gaaattctcc caaagtcaga gttttatttc
     6661 taacttttga gagaacttca tttttgattc agactttttc tactgctatt ccttacgcta
     6721 tgagatcaga taaattcttt tttatcactt ctccacttgg caatcttaat tcaatcgttc
     6781 catccatatt gaatataaca ctatctaagc ctaatccgta actagctgta aatttttcta
     6841 atttttcttg tacaggatct actgctggag cttcctctaa tgctggatct aacatagggt
     6901 cactccccac attcccttct ggattcaaca ttccattatc cgttgagttt tctggtttta
     6961 caggtttttc gtttggtgcc tctggtaaag aatctgctgg tttattttct gttggttggt
     7021 tctcaactgt tccagtagat acttttccat tttcagatgg tttattttca ccatttcctt
     7081 gaggtgcttc tcctgtaaaa tctgccatat tctttttaat gacttctccc gatggtaaat
     7141 ataattcaat tgttccgtcc atattaaaca agacattttc tagcttcatc ccataacttt
     7201 cagcaaattt tgctactttt tcttgtacag gatccactgt aggaacttct tctaacgttg
     7261 aattactagt actattccca gtttcagaaa gtttttcttt ttctaccttc tcactagtct
     7321 ttggttcttc taccttttca tcaagttttg agttttcttg tgctttattc cttttaaatt
     7381 gtggtagaat acttggttta tcagtttgat tttctttttc caagataggt acttccacaa
     7441 tataagtcga ttgattgtcc aaataagcat ttgccatgaa ggttacagga attttatttc
     7501 cggccgttct ggttgttcct tggtttaatt tcggaatcgg taatttgatt tcaccaactt
     7561 tatagttatt ttctaaataa gcatttccat gaaattcatc aaacactctg actaaagcat
     7621 cagttccttt aggcactgca aattgagggt tcactcttaa ataagtatcc cctgcatgga
     7681 aaggatagaa aatcgtttga ctggccattt tgtaagctaa agaggttgga actgtaaatg
     7741 taccatcata acttacttct ggataatctt ttgaagcgat agtatactta aatgtttgtc
     7801 ctggtaaata aggttgatct aattcaaagt ttgcaatatt ccctactcct tctccaaata
     7861 ctttaccaga tactttctcc aatacttttc catctggtgt tattaatttt actagcatat
     7921 tgatacctaa ttttttctcc aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat
     7981 tggctagagt aaagttttga ttattaaacg tactattttt taacaaatta acaacattcg
     8041 ttaattcttc tccagtataa actttattcc cttctttttt agcaactcct tcttcgggtt
     8101 taaacagttc atagttactg tgagaatgac caattccaac cggtttatgt tcatcaatcg
     8161 gatctgcatg atggtgatct ccatgcggat aaataatcgc atttttttct ttattcacga
     8221 caatactttc acgtttgaca ccatattgtt tcataatgcc agcaattttt tcttcgattt
     8281 ttttatctaa atctttcatt tctttggcat tacttggata atcctgttca tgagatgaca
     8341 aagaatctaa tccattatga ctagttttaa cttcctctaa atgtttttgc gcagccttaa
     8401 tttgctcttc tgtcaagtcc ttcttgaaga aataatgatt gtggtctccg tgactcatga
     8461 caaaacctga ttcatcttca gcgataatac gattagcatc aaatccgtat ccatcttctt
     8521 catgtttctc atgtgaagtt cctggattga ttggaagaga tggagaaggt gttgctagac
     8581 tattgtttgg aagagtcggt tgcccaattt gatttgattt tggaatgtaa tggaaatgat
     8641 caccatgtct tacaatataa gctgtagccg tttcttcaac gatatctttt ggattaaaaa
     8701 tataaccatc agatgctgaa gagagctcct tacttgtcgt taaagaagaa ggattgcttg
     8761 aaagactgcc tagactagac actacttcat taggttttgc atttgtagaa actgtagaac
     8821 cagttccact gataggcacc attctggcaa tcttttcttc taaggcagaa agcttgctgt
     8881 aaggaataaa gtggtaatgg tcgccatgcg gaatcgcaac tccatttggt gtacgactga
     8941 taatcttagc agggtcaaag accaggccat ctgattcact gtaacgttgg gcgctaggtg
     9001 aatcatagag ttccttcaaa agactctgga gattttcaga tttatttgct ggcttgctag
     9061 ttgatccttt tgctacagat tgcgtgttat tgtcactagc tgttgaagaa tagcttaact
     9121 gactcggttg catatttttt ccagccagat gtgctttagc tgctgctaat tcactagcag
     9181 ataaatcgct tttgggaatg tagtgatagt gacctccatg aggaacgata taagcattac
     9241 ccgtatcttc gataatatca gctggattaa agacataacc atcatttgtc gtatatcgtc
     9301 cctgagacct tgctacagca acattagagt taaccttctc attatctttg acatgttctt
     9361 gtttttgacg attgatttca tctttagttc gaacattatc agcatgagct gcatctttca
     9421 ggtagacata atattttcca tcgaccttga tgatataacc acccttgact tcattgacaa
     9481 tatcagcgtc tttaagttga tagtttggat ccttcatcaa gagttcttca ctaaagaggg
     9541 catcataagg aactttccca ttatagtaat gatagtggtc accgtgtgac gttacatagc
     9601 cctgatctgt aattttgatt acaatttgct cggcctgaat tccttctttc tggctaacct
     9661 ggtctggtgt caagttttca cttttctgac ttgactggct gccatccaca taagagacac
     9721 gattattgtc cttattttcc tgcgaacgat gctggtttag tgcataggca catagactca
     9781 aggatacgat aacagctgat ccagctgcta tatatttttt actgaatttc ataaatccct
     9841 catttcaata aatgatgaag ttttttctca acttctttta ctttattaaa tagttttcta
     9901 aaccggttat ttaaccattt aattaaccag taaatagttt actatttaaa attacttttg
     9961 tcaagtttct gttacgtttt tctaaaaaag agaagtaaca cgaaaggtta cttctccata
    10021 aaatatgctc cattcatttt actactgtat aggagccagt tgactttttt ttaacaaagc
    10081 caagagacta tctacttctg ctgaaatagt gttattatct ttcgttccga gaagaagact
    10141 actttttaga ccagtcaatg tctccatagc attttgtcta atactaggat ctgttacttt
    10201 ttctagcaag gcctccgcat ctgctatctt agcgttaata acagaatgct ctacttgagg
    10261 aatttcagcc tcatctgtag tatcttcagc ttcttcctct gtctcttccg tatcagtgct
    10321 tggtttataa agattatctg ctgaaggatt taaaccagcg tgattctctt tttcatcaga
    10381 ttcagggtga gttggctcac ttacttcatc atgtccctta tcttcatcag gtttactatc
    10441 ttggtctgcc ttattttta
//
LOCUS       DBEJZJ010000050         9931 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000050 DBEJZJ010000000
VERSION     DBEJZJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.50"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(28..1731)
                     /gene="ilvD"
                     /locus_tag="ACL3R8_001830"
     CDS             complement(28..1731)
                     /gene="ilvD"
                     /locus_tag="ACL3R8_001830"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR1314657.1"
                     /translation="MTELDKRHHSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1964..2896)
                     /locus_tag="ACL3R8_001831"
     CDS             complement(1964..2896)
                     /locus_tag="ACL3R8_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR1314658.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2893..3750)
                     /locus_tag="ACL3R8_001832"
     CDS             complement(2893..3750)
                     /locus_tag="ACL3R8_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR1314659.1"
                     /translation="MILSKNREDELRKFAANIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPETFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(3754..5100)
                     /locus_tag="ACL3R8_001833"
     CDS             complement(3754..5100)
                     /locus_tag="ACL3R8_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1314660.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5113..5397)
                     /locus_tag="ACL3R8_001834"
     CDS             complement(5113..5397)
                     /locus_tag="ACL3R8_001834"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1314661.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5401..7431)
                     /locus_tag="ACL3R8_001835"
     CDS             complement(5401..7431)
                     /locus_tag="ACL3R8_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR1314662.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPIIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            7622..8629
                     /locus_tag="ACL3R8_001836"
     CDS             7622..8629
                     /locus_tag="ACL3R8_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR1314663.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8632..8832
                     /locus_tag="ACL3R8_001837"
     CDS             8632..8832
                     /locus_tag="ACL3R8_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR1314664.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            8983..9165
                     /gene="rpmF"
                     /locus_tag="ACL3R8_001838"
     CDS             8983..9165
                     /gene="rpmF"
                     /locus_tag="ACL3R8_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR1314665.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9181..9330
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001839"
     CDS             9181..9330
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1314666.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9822..>9931)
                     /locus_tag="ACL3R8_001840"
     CDS             complement(9822..>9931)
                     /locus_tag="ACL3R8_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR1314667.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3225 a         2105 c         1598 g         3003 t
ORIGIN      
        1 gatttgaaga gattttcgag tatgagttta ttttttacct gacttgtcca tattccagaa
       61 gtctgtcacg gctccgcgtg aagcagatga tacgatgtgg gcatatttac cgaggacacc
      121 acggctgtaa agtggtggca aggttgtttc tgccttgcgt ttttcaagtt cttcttcgga
      181 tacggccatg gaaatttctt tggtatcttg gtcaaccgta acgatatcgc cggtacggag
      241 ataggcaatt ggtccaccat cctgagcttc aggagcgata tgtccaacaa ccagaccata
      301 agtaccacca gagaaacgtc cgtccgtcaa gagggccacc ttatctccct gacctttacc
      361 aacaatcatt gaagaaagtg acagcatctc aggcatacca ggaccacctt taggtccaac
      421 aaaacgaaca acgactacat cgccatcaac gatttcatct gtcagaacgg cctgaatcgc
      481 atcttcttct gagtcaaaga ccttagctgg cccaacgtga cgacgcactt taacacctga
      541 taccttggca actgcaccgt caggagcaag gttcccgttc aagatgataa gcggaccatc
      601 cgcacgtttt ggattttcaa gtggcatgat aactttttgg cctggagtca agtctgcaaa
      661 gtcagccaag ttttcagcta cagtcttacc agtacatgtg atgcgatctc cgtgaaggaa
      721 accatttgcc aacaagtact tcataaccgc agggacacca ccgacttcgt agaggtcttg
      781 gaagacatac tgaccagatg gtttcaagtc ggccaagtga ggcacacgtt cttgaatcgt
      841 attgaagtcc tcaagtgaca agtcaacatt tgcggcatgg gcaatggcga gcaagtgaag
      901 agtggcgttt gtagaaccac cgagagccat cgttacagta atagcatctt caaaggcttc
      961 acgagtcaag atatctgatg gtttgagacc aagttccaac atcttaacaa cagcacgtcc
     1021 tgctgcttcg atatcttctt tcttatcagc tgattcagct gggtgagagg atgaccctgg
     1081 caaactcatc cctagaactt cgatagcagt tgccatggta ttagcagtat acataccacc
     1141 acagccacca gggccagggc aggcattaca ttcaagacgt ttcacgtcct cagctgtcat
     1201 gtcaccgtgg ttccattttc cgataccttc aaagacagaa accaagtcga tatctttacc
     1261 atcaagattt cccggtgcaa tagttccacc ataggcgaaa atagctggga tatccatatt
     1321 agcaatagca atcatagatc caggcatgtt cttgtcacag ccaccgatag cgacaaaggc
     1381 atccacgttg tgaccactca tagccgcctc gatggagtcc gcgatgatgt cacgagatgt
     1441 tagagagaaa cgcataccag gcgttcccat agcgatcccg tctgctacgg taatggttcc
     1501 aaactgtaca ggccaagcgc ctgcagattt gacaccttct ttagccagtt tcccgaaatc
     1561 atgcaagtga atgttacatg gtgtattttc cgcccaagtc gaaatcactc ccacaatcgg
     1621 tgtttcaaag tccttatctg tcataccagt cgcacgaagc atagcacggt taggtgattt
     1681 aaccatgctg tcataaatgc tactgtggtg acgtttatct aattcagtca tcttatccct
     1741 cccatttcag tttttactat tatagcacaa ttttcgcatg aagaacagaa taaaaatctt
     1801 gaattttcag aaaattctat acacatgtga aatatttaaa attaaaaaca acaaagcgga
     1861 ttagtgcact ttctgatgac cagaatatgc tttttaatcc gctttcttta aataacgtac
     1921 tgtaattttt acagaaattc tttcagataa gtgtatttaa catctatctt gcattataaa
     1981 tttctagaac cttctctttt atattcgatt cactcaaacc atactcatta agaagataat
     2041 ccattttccc tacttgaccg aatctttctt gaacacccat ccgatgaatt tttgtcattc
     2101 catcatcaga gaataattca cataaagaac tgccaattcc acctatctga ttgtggtttt
     2161 ctacagtaaa tatagttttt ccacttaaca ttgtttttat ctgttctggt atcggtttga
     2221 ttctaaataa atctatcaca cttactgaat aacctaattt agacagttca tctgcaactc
     2281 gaatacttgg agcaaccatt ataccagaag caacgattac aagatcttca ccatgcctta
     2341 actcaatgta gcctttagaa aaatcttctc caccttgata cacaggaact ggagcttttc
     2401 taattgttcg aatatatttt agtcctttta agtctaatgt ctggttcaat atttcacgaa
     2461 attggatatc atcagttgct tcaaaaatga tcgatttagg aattaaacgt aacaatccaa
     2521 tttcttcaaa tggcatatgt gttccaccat tcatctctgc cgttactcct gcatctgatc
     2581 caatcacagt ggcatccaat tgtgcgtatc caagagaaat aaataattga tcaaatactc
     2641 ttcgtgaagc aaaaggacca aatgtatgaa gataaggtct aaacccctga atagacaagc
     2701 ctgctgcaag gccgaccatt tctgcttcca taatcccaac attcacataa cggtctccaa
     2761 aatccttttc aagattatta gtagccatcg aacttgacaa atcggcttct aagactacta
     2821 tatcagaata actttgatta gcctctaaaa ggaagtctct atatacatgc cgtaattctt
     2881 tcgtgcttct catcattctg tttcctccaa ttcctgactt aatctttcta caactgaagt
     2941 taacatttgt ctctcctcta cagtagggcg aagatgatgg ttggatttca tttcttccag
     3001 ctcttgaacc ccttgacctt taatagtatc taatacaatg cacttaggtg atgaattatt
     3061 tgactgtttt aattggacaa tcccttcata aatttctcta atatctgaac ccttgaccct
     3121 aatggattca aatccaaatg ctgaaaattt ttctacgaaa tcacctggat tacaaatatc
     3181 ctttgtaaaa ccatctaatt gttttttgtt atcatcaaca aatacaatta agttggataa
     3241 ctgttgatga gaagcaaact gtatagcctc ccaacattgt ccctcattta actcaccatc
     3301 tccaacaata gcataagtat aaaagggact ctttcttatt ctctgaccat atgcaagtcc
     3361 agttgcaaca ctaattcctt gtcctaaaga gcccgttgtc atatctatgc ctggcgttag
     3421 atttctatca ggatgagacg gtaatttggt tccatttgta tttaaagaat ataagaattc
     3481 tttgtcaaag aaaccattca aatagagtgt actgtataga gctggtcctc catgaccttt
     3541 tgataatatg aaataatctc tatctcgtgc tgcaaatgtt tctggagtca ttggcattat
     3601 ttcaccataa agcactgcta aaacttctac gatagacaga cttcctccgt aatgtccgaa
     3661 tccaagatga ttcaatgttc taagagtatt taatcggatg ttagccgcaa attttcttaa
     3721 ctcatcttct ctatttttac ttaaaatcat cccttattcc tcctttgcag atggcttttt
     3781 aataaaggat actccaaaca taactgctaa aataagaaca agaccaatca caatgcctgc
     3841 ttgtgagcca aattgattta acattcctaa aataattcct gatagaccaa aatctgcatc
     3901 tgagaaagtt gatccttgga aaccgagtcc tcccaaaact ggcattaaaa agactgggag
     3961 aaaactgatt aaaatacctt gtaaaaatgc tccaatagtg gctccacgaa caccaccaga
     4021 tgcattccca ataacacctg cagtcgctcc acagaagaaa tgaggcacaa cgcctggtaa
     4081 gataacaacc gttcctgaag caatcataat tgccatactt actaaaccac caataaaact
     4141 agagataaat ccaattagaa ctgcattagg tgcataagta taaacaatcg gacaatccaa
     4201 agcaggtttt gaattaggta caagacgctc tgaaatacct ttaaaggctg gaacaatttc
     4261 gcccaaaata aggcgaacac ctgctaaaat aacaaatacc cctgctgcaa attgacctgc
     4321 taattgtaaa gcataaacta gaccacttgt accactactg atttcttttt ctatatattc
     4381 tgaccctgca aagatagcta caataatgta aataactgcc atagataaag tgatactaac
     4441 agtactatca cgtaaaaaag ctaaactctt tggaaattta atgtcctctg ttgattttga
     4501 tttgtcaccg ataaggctac cagtaaaacc actcaaccaa tatcccaaag aactgaaatg
     4561 acctaaagcc accttgtcat ttccagttaa ttgaaccata tatttttgca caaatgctgg
     4621 ggaaatactc ataataatac cgagtgctaa tcctcctagt aagatgagag gcaagctagt
     4681 aaagccagca actgataaaa tgaccgcaat catacatgcc atatatagag tgtggtgccc
     4741 tgttaaaaaa atatatttaa atcgagtaaa acgagcgatt aagatattga acaccattcc
     4801 tgcaaacata atcattgcag tagctgagcc atatgttgtt aaagctacag ctacaattgc
     4861 ttcattattc ggcacaacgc cagataaatg aaaagcatgc tcaaacatgg taccaaatgg
     4921 atttaaagaa ttttgtacaa ttcctgcacc accagataca actaagaaac caacaaaggt
     4981 cttaattcca cctttaataa tatcaggtaa tttcttcttc tgaagaacta atcctaaaat
     5041 tgcaattaaa gctactaaaa tagctggtgt actaacaata tccaatatga acttcatcat
     5101 gacgctagcc tcctatataa gtcctttttc ttcacaaagt ttagtaatta attctcgtag
     5161 ttcatccata tcaataatac tatttaagat acgaacatct ccaagatgac tagctgaatc
     5221 agctagatca cgaccaacaa tccaaatatc agctgcattt ggatctgctc cacctaaatc
     5281 ataatgttca acttctacat ccgaaacatt caaatcactc aatacagatt caatattcat
     5341 ctgtaccata aaacttgaac ctaatcctga accacaagct gtaccaattt ttaacattat
     5401 ctaatcctcc tgtttaatta tcattttaat atcattatag ttttttgatg atattaaagt
     5461 ttgaacatga tttttatctc ttaaaattgt tgttaaatgt gacaaagcct ttaaatgact
     5521 ctcattatca atggctgcaa tacaaatcaa caatcttacc tcttgttctg gattatccaa
     5581 taaataaatc ggttcttcca aaactaacat tgacattcct atttcattca caccttcatc
     5641 tggccgagcg tgaggaattg ctactccctt ccctaaatta ataaaaggtc caaactcttc
     5701 tactttttga atcattgcct cagggtagtt ctcagttatc ttatcttgat ccaaaagcgg
     5761 tttagctgct aaacgaatcg cctccttcca tcctaatttt tgcgaactaa cctgataggt
     5821 ttctttggta ataagttgtt ctagcactgg tacaatttcc tttctatcat ttttttgata
     5881 aagataattc tttaacgcca atcttaattc caattcttgt gtaataattc catatctttt
     5941 gacaatattc aggatttgtt caatctcaaa atctccatac tctaaattcg gaaaatcttt
     6001 taacactagt tctactagtt gtattgcttg ctcttcagtc atcataaccg aaactagata
     6061 atttggcttt tctgtctcca cctttatggt agaaaaaacc atatcatagt cactactaac
     6121 tttcacctgt aaatcatcaa tctttgaggt tcctataaac tcaatttgag gaaataatgc
     6181 taatagattc tcttttaaca tcaatgaaga actaacacca ttaggacaaa tgattgctgc
     6241 tttataccat ttttgaggca aagtatctgc tttctttaaa taacctccga aatggataac
     6301 aaaatatgct gtttcactat caggtatggg attgtcaata gcgtccatca agggcatcaa
     6361 agaatctttg actaattcaa ataaatcagg ataatgttct ttaacatgca atacatattc
     6421 atttgaacta ggtaggccga actttaatct atagtaagcc ggtataaggt ggcggcgaag
     6481 attttctctc aatccttccc tttgtttaaa atgtaacaaa gaaatatctt ccattctact
     6541 tataatagcc tctgttaatt gattaaagta aaccggagca acatctactt caccttcaaa
     6601 gcaacttgat aataaaacgg tgatatagcg ataatcatcc tcagaaaaca ccgtatctat
     6661 aattcccaaa tcaaccactg tatccaataa aatagtcgtt atatcttgaa taataggaga
     6721 tactaatgtc tctgaaagac acactctttc aacatccctt tgatacctac acagaatgaa
     6781 tactaaaccg aaaaggtaaa cttttaattg attaacaata ggtactagct gtagcttctc
     6841 ataataatct ttaactacct gatcaatcaa atcataagtt aatgaatacc cccaactgga
     6901 taaaacataa tccaaacccc aaatccctat ggaggattcc agcaactcac taaccatttg
     6961 aaaagctaag cggtgcttat tccactctga accgtgtaaa gtataacctt ttgctctact
     7021 gtaccctagc tccaaatcat tatctaacat aatctttctt aatgattgaa tatcagataa
     7081 ggttgtattc ttacttactt tcaaaaagtc ttggtaatga ctattcgata taaaatctaa
     7141 tcggcaaaaa gtgtaaagat agattaaagc taagcgagtc gactttggta aaaccaattc
     7201 atccgactta ataatatctg tcaaagactg cttcgtacga tttgataaac tatagcgacc
     7261 ttgcttttta tccagcacta tccctttatt agctagataa ggcactaaat aatctattcc
     7321 ttctttgact tcctttatag gtaagctcac cttaacagat aattcatata atgatagctc
     7381 acaatgatcc atcaaagtca tcaaaataac tagtgctcta taatcaaaca tctctcttcc
     7441 tttctaacta caattatagt gtaaaaatta taagaataaa agagtatttg agcacaatat
     7501 aatctcacct tttaaaagaa attattgggc tgaaactttt tagtgattat tttcaacttt
     7561 ctattgactt ttaaaaacaa agtgatatca tttagatatc aaataatggg aggtcattct
     7621 tatgactgaa aaactaatca attcaaaacc aaatggtgta ttcgcattga ttctcattga
     7681 gttgacaatc gtacttggta tctttatatt tataatgggg gttggttcgg aaaacatttt
     7741 tggaattatt atcggacctt tactaatcgt aattgcaggt ctagctcatg ctggtttaaa
     7801 agttgtcaaa cctcaggaag ctctggttct gacactcttt ggtaattata caggtaccat
     7861 caaagaacct ggtttttact ttgtcaatcc cttcagcgta gcagtcaacc ctgcaaacca
     7921 cactcgactt ggacaaagtg gtgatgttag cacaaaatct ccttttttag gagctaaatc
     7981 atcaaatgac aatgatgtaa atcttgaaat tggcaagaaa cacatttccc tcaaagtcat
     8041 gaccttgagc aattctcgtc aaaaaatcaa tgattgctta ggaaaccctg tagaaatcgg
     8101 tatcgcggta acttggagag ttgtcgatac cgctaaggca gtcttcaacg ttgataacta
     8161 caaagaatat ctttcattgc aatgtgatag cgccctccgt aatattgtcc gcatctatcc
     8221 ttacgatgtg tctcctaatg tggatactac gggtgacggg caagcagatg aaggtagtct
     8281 ccgtggctct agcgaaattg ttgctaaccg tattcgtgaa gaaatccaaa gtcgtgttga
     8341 ggatgctggc ttggaaatcc ttgaagcacg tatcacttac ctagcttatg ctccagaaat
     8401 tgctgccgtt atgcttcaac gccaacaagc atctgccatt attgatgcac ggaagatgat
     8461 tgtagatggt gctgtaggaa tggttgaaat ggcactagaa cggctcaatg aaggggaatt
     8521 ggtagaactt gacgaagaac gaaaagctgc catggtttca aatctccttg tcgttctttg
     8581 tggcaatcat gatgcacaac caattgtcaa cacaggaagt ctttactaaa gatggctgaa
     8641 gctaaaaaaa agcagatccc ccttcgactc tcaacaaagt tatacgctgc actcgcatca
     8701 tgggcagaag acgactttcg ttcagtcaat gggcaaatcg aatatctcct cacagagtgt
     8761 gtcaagcaac ggaagaaaga cggaaaatac gtatcagaaa ccattgacga accatttgag
     8821 attgatattt aacaccttct cctgtctgcc gtgtcggata ggagaatttt ttcatctttt
     8881 ttgtcaagta actttacttt acaaaaaaaa tgtgttatcc tagtatggtt gatgaaaatc
     8941 agtagattga atcgaatata aatacctaaa ggagaaatca aaatggcagt acctgcacgt
     9001 cgcacttcaa aagcgaagaa aaacaaacgt cgtacacact acaaagtaac agctccatct
     9061 gtaaactttg acgaaactac tggagattac tcacgttctc accgtgtatc acttaaagga
     9121 tactacaaag gacgtaaaat cactaaagct gcatcagctg aataatagaa gggagatacc
     9181 atgcgcgtaa atattacact tgaacacaaa gaatctggtg aacgcttgta ccttacttct
     9241 aaaaacaaac gtaacactcc agaccgcctt caattgaaga aatactcacc aaaacttcgc
     9301 aaacacgttg tgtttacaga agttaagtaa gcattcaata cgaatcaata cagaagaaaa
     9361 acgcttgatc agcggttttt ctttttgtta atttcactat attgcaaggg aaatcattcg
     9421 aatgactaca tttttcacta ccttttttga aataagaata cggattcgga cgattaaaag
     9481 taagagaaac tcaaatgtaa gttggggttc cttttttgta tatttttcaa ataacgcctc
     9541 tacactattt gtagcaaatt caccaactac agttgtatct tagttaaaat aagttagaat
     9601 atgtaagtga gtaccagata taccaagaca tcgtcaccat ctaaggtata ttcaaaatac
     9661 aaaagttgac caactagatt tctgaatatc cttatatatc cattcttaaa attggtttaa
     9721 atagcgtagt cttttaaact agttttgaga atccaaaaaa tcttcctaca tatgtaagaa
     9781 gattttttag ttcagaatga ttagatttag ctaatggata cctatcctac ccactcaccg
     9841 ttagcattga ctcgatagcc atcgggtgta gtcgtgttta ctaataaatc tcctgaatta
     9901 taggtatagt accatttacc agaaactgta a
//
LOCUS       DBEJZJ010000051         9748 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000051 DBEJZJ010000000
VERSION     DBEJZJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.51"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            272..6703
                     /locus_tag="ACL3R8_001841"
     CDS             272..6703
                     /locus_tag="ACL3R8_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR1314668.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDNNTSNEEARIKE
                     DSNQSQGDNAHSSANKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLTGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYINGKEYTSFDDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REEHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            7330..7806
                     /locus_tag="ACL3R8_001842"
     CDS             7330..7806
                     /locus_tag="ACL3R8_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR1314669.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7844..8149
                     /locus_tag="ACL3R8_001843"
     CDS             7844..8149
                     /locus_tag="ACL3R8_001843"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1314670.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8197..9672
                     /locus_tag="ACL3R8_001844"
     CDS             8197..9672
                     /locus_tag="ACL3R8_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR1314671.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNTAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYATKAK"
BASE COUNT         3601 a         1466 c         1877 g         2804 t
ORIGIN      
        1 acctgcggct agtttcctag tttgctcttt gattttcatt gagtactaat cttatttttt
       61 aacgtgtgct aaaaaataaa ttaatgcatg ttaatttttc ttgaattaaa tttttttaaa
      121 tgatatactg tttttatgga gagataacaa ttatatataa atgtactact ctatttccta
      181 gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt tattatctat
      241 tggagtttaa ataaatatgt aaggaattaa aatgaaaaaa agtacagtat tgtcattaac
      301 cacagctgca gttattttag cagcctatgc ccctcatgag gtagtcttag cagacacatc
      361 taactctgaa gatgctttaa gcatctctga taaagaaaaa gtagtagtag ataaggaaac
      421 agaaaataaa gagaaacata aagatattca taatgctata gaaacttcaa aggatactga
      481 agaaaagaaa acaacaatta ttgaggaaaa agaagttgtt agtaaaaatc ctgtgataga
      541 caataacact agcaatgaag aagcaagaat caaagaagat tccaatcaat ctcaaggaga
      601 taatgcacac tcgtctgcaa ataaaaacac agaaaatccc aaaaaagaag ataaagttgt
      661 ctatattgct gaatttaaag ataaagaatc tggagaaaaa gcaatcaagc aactatccag
      721 tcttaagaat acaaaagttt tatatactta tgatagaatt tttaacggta gtgctataga
      781 aacaactcca gataacttgg acaaaattaa acaaatagaa ggtatttcat cggttgaaag
      841 ggcacaaaaa gtccaaccca tgatgaatca tgccagaaag gaaattggag ttgaggaagc
      901 tattgattac ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg gtagaggtat
      961 ggtcatttca aatatcgata ctggaacaga ttatagacat aaggctatga gaatcgatga
     1021 tgatgccaaa gcctcaatga gatttaaaaa agaagactta aaaggtactg ataaaaatta
     1081 ttggttgagt gataaaatcc ctcatgcgtt caattattat aatggtggca aaatcactgt
     1141 agaaaaatat gatgatggaa gggattattt tgacccacat gggatgcata ttgcagggat
     1201 tcttgctgga aatgatactg aacaagatat caaaaacttt aacggcatag atggaattgc
     1261 acctaatgca caaattttct cttacaaaat gtattctgac gcaggatctg ggtttgcggg
     1321 tgatgaaaca atgtttcatg ctattgaaga ttctatcaaa cacaacgttg atgttgtttc
     1381 ggtatcatct ggttttacag gaacaggtct tgtaggtgag aaatattggc aagctattag
     1441 ggcattaaga aaagcaggca ttccaatggt tgtcgctacg ggtaactatg cgacttctgc
     1501 ttcaagttct tcatgggatt tagtagcaaa taatcatctg aaaatgaccg acactggaaa
     1561 tgtaacacga actgcagcac atgaggatgc gatagcggtc gcttctgcta aaaatcaaac
     1621 agttgagttt gataaagtta acataggtgg agaaagtttt aaatacagaa atataggggc
     1681 ctttttcgat aagaataaaa tcacaacaaa tgaagatgga acaaaagctc ctagtaaatt
     1741 aaaatttgta tatataggca aggggcaaga ccaagatttg ataggtttgg atcttagggg
     1801 caaaattgca gtaatggata gaatttatac aaaggattta aaaaatgctt ttaaaaaagc
     1861 tatggataag ggtgcacgcg ccattatggt tgtaaatact gtaaattact acaatagaga
     1921 taattggaca gagcttccag ctatgggata tgaagcggat gaaggtacta aaagtcaagt
     1981 gttttcaatt tcaggagatg atggtgtaaa gctatggaac atgattaatc ctgataaaaa
     2041 aactgaagtc aaaagaaata ataaagaaga ttttaaagat aaattggagc aatactatcc
     2101 aattgatatg gaaagtttta attccaacaa accgaatgta ggtgacgaaa aagagattga
     2161 ctttaagttt gcacctgaca cagacaaaga actctataaa gaagatatca tcgttccagc
     2221 aggatctaca tcttgggggc caagaataga tttactttta aaacccgatg tttcagcacc
     2281 tggtaaaaat attaaatcca cgcttaatgt tattaatggc aaatcaactt atggctatat
     2341 gtcaggaact agtatggcga ctccaatcgt ggcagcttct actgttttga ttagaccgaa
     2401 attaaaggaa atgcttgaaa gacctgtatt gaaaaatctt acgggagatg acaaaataga
     2461 tcttacaagt cttacaaaaa ttgccctaca aaatactgcg cgacctatga tggatgcaac
     2521 ttcttggaaa gaaaaaagtc aatactttgc atcacctaga caacagggag caggcctaat
     2581 taatgtggcc aatgctttga gaaatgaagt tgtagcaact ttcaaaaaca ctgattctaa
     2641 aggtttggta aactcatatg gttccatttc tcttaaagaa ataaaaggtg ataaaaaata
     2701 ctttacaatc aagcttcaca atacatcaaa cagacctttg acttttaaag tttcagcatc
     2761 agcgataact acagattctc taactgacag attaaaactt gatgaaacat ataaagatga
     2821 aaaatctcca gatggtaagc aaattgttcc agaaattcac ccagaaaaag tcaaaggagc
     2881 aaatatcaca tttgagcatg atactttcac tataggcgca aattctagct ttgatttgaa
     2941 tgcggttata aatgttggag aggccaaaaa caaaaataaa tttgtagaat catttattca
     3001 ttttgagtca gtggaagaaa tggaagctct aaactccaac gggaagaaaa taaacttcca
     3061 accttctttg tcgatgcctc taatgggatt tgctgggaat tggaaccacg aaccaatcct
     3121 tgataaatgg gcttgggaag aagggtcaag atcaaaaaca ctgggaggtt atgatgatga
     3181 tggtaaaccg aaaattccag gaaccttaaa taagggaatt ggtggagaac atggtataga
     3241 taaatttaat ccagcaggag ttatacaaaa tagaaaagat aaaaatacaa catccctgga
     3301 tcaaaatcca gaattatttg ctttcaataa cgaagggatc aacgctccat catcaagtgg
     3361 ttctaagatt gctaacattt atcctttaga ttcaaatgga aatcctcaag atgctcaact
     3421 tgaaagagga ttaacacctt ctccacttgt attaagaagt gcagaagaag gattgatttc
     3481 aatagtaaat acaaataaag agggagaaaa tcaaagagac ttaaaagtca tttcgagaga
     3541 acactttatt agaggaattt taaattctaa aagcaatgat gcaaagggaa tcaaatcatc
     3601 taaactaaaa gtttggggtg acttgaagtg ggatggactc atctataatc ctagaggtag
     3661 agaagaaaat gcaccagaaa gtaaggataa tcaagatcct gctactaaga taagaggtca
     3721 atttgaaccg attgcggaag gtcaatattt ctataaattt aaatatagat taactaaaga
     3781 ttacccatgg caggtttcct atattcctgt aaaaattgat aacaccgccc ctaagattgt
     3841 ttcggttgat ttttcaaatc ctgaaaaaat taagttgatt acaaaggata cttatcataa
     3901 ggtaaaagat cagtataaga atgaaacgct atttgcgaga gatcaaaaag aacatcctga
     3961 aaaatttgac gagattgcga acgaagtttg gtatgctggc gccgctcttg ttaatgaaga
     4021 tggagaggtt gaaaaaaatc ttgaagtaac ttacgcaggt gagggtcaag gaagaaatag
     4081 aaaacttgac aaagacggaa ataccattta tgaaattaaa ggtgcgggag atttaagggg
     4141 aaaaatcatt gaagtcattg cattagatgg ttctagcaat ttcacaaaga ttcatagaat
     4201 taaatttgct aatcaggctg atgaaaaggg gatgatttcc tattatctag tagatcctga
     4261 tcaagattca tctaaatatc aaaagcttgg cgagattgca gaatctaaat ttaaaaattt
     4321 aggaaatgga aaagagggta gtctaaaaaa agatacaact ggggtagaac atcatcatca
     4381 agaaaatgaa gagtctatta aagaaaaatc tagttttact attgatagaa atatttcaac
     4441 aattagagac tttgaaaata aagacctaaa gaaactcatt aaaaagaaat ataaggaaga
     4501 agacgacttt gtaactggtg gaaaaagaac agtagaactt gattataaat atgacgataa
     4561 aggaaatata actgcctatg aagatgaaag tgctctagaa tatgaaactg aaaaatttga
     4621 cgaaataaaa tcaaaaattt atggtgttct aagcccatct aaagatggac actttgaaat
     4681 tcttggaaag ataagcaatg tttctaaaaa tgccaaggta tattatggaa ataactataa
     4741 atttatagaa atcaaagcga ctaagtatga ctcacattca aaaacgatga tatttgattt
     4801 atacgctaat attaatgata ttgtagatgg attagctttt gctggagata tgagattatt
     4861 tgttaaagat gacaatcaaa taaaagctga aactaaaatt agaatgcctg aaaaaaataa
     4921 ggaaactaaa gcagaatatc cctatgtatc aagttatggg aatgtaatcg aattaggaga
     4981 aggagacctt tcaaaaaaca aaccagacaa tttaactaaa atggaatctg gtaaaatcta
     5041 ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa gaaaaggcta
     5101 tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag gaaatggagt
     5161 ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa gagtcctttc
     5221 agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta cccaagctgt
     5281 attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta catttaaaat
     5341 gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt cttctaaact
     5401 tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca atgtagaagc
     5461 tataaaagaa gatggctcca tgttatttat tgataccaaa ccagtaaacc tttcaatgga
     5521 taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc cagaatttta
     5581 tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag ttaatgaatc
     5641 ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta gagattttaa
     5701 tattaagctg aatgttaaag acggtgacat catggactgg ggaatgaaag actataaagc
     5761 aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc aaactggcta
     5821 tagtgatttg aatgctaaag cagttggagt ccactatcag tttttatatg ataatgttaa
     5881 acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg atggaaaatc
     5941 tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga ttcaagaaca
     6001 acatatttat ataaatggaa aagaatatac atcatttgat gatattaaac aaataataga
     6061 caagacacta aacattaaga ttgttgtaaa agattttgca agaaatacaa ccgtaaaaga
     6121 attcatttta aataaagata cgggagaggt aagtgaatta aaacctcata gggtaactgt
     6181 gaccattcaa aatggaaaag aaatgagttc aacgatagtg tcggaagaag attttatttt
     6241 acctgtttat aagggtgaat tagaaaaagg ataccaattt gatggttggg aaatttctgg
     6301 tttcgaaggt aaaaaagacg ctggctatgt tattaatcta tcaaaagata cctttataaa
     6361 acctgtattc aagaaaatag aggagaaaaa ggaggaagaa aataaaccta cttttgatgt
     6421 atcgaaaaag aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa gtcacagaaa
     6481 agaggattta caaagagaag agcattcaca aaaatctgat tcaactaagg atgttacagc
     6541 tacagttctt gataaaaaca atatcagtag taaatcaact actaacaatc ctaataagtt
     6601 gccaaaaact ggaacagcaa gcggagccca gacactatta gctgccggaa taatgtttat
     6661 agtaggaatt tttcttggat tgaagaaaaa aaatcaagat taagataaaa gctatagaaa
     6721 aaaatggttt atgtactgag attagatagt gaggtgatga catagttttg tgaaaacagc
     6781 catttataac tcaattattt agtttacttc actattgata ctatttggag ttattaatgg
     6841 acttagttta gataactaat gaattgattg aaagggttag tattgacaat attggtcata
     6901 ttgattagaa aatagagtct atcaaaattt aaaggctaat agaggtgatg agacaatttc
     6961 aaggaattaa gtagcgtttg gttgcttaat tcctttttat ttggaaggaa gtttttcgta
     7021 accgcccaat aacgaagtct attggacggt tacgatatga tcactgactt cgtcagtctt
     7081 atctacaacc tcaaaactgt gttttgagca acctgcggct agcttcttag cttactcttt
     7141 gattttcatt gagtattaga acagaaaaaa tgcttggagt atttgtttgt gtgtttgttt
     7201 ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa
     7261 gtaattgaca acggtttcat atagtgttat acttatggca taaagttaat ggaaagaagg
     7321 gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg
     7381 gataatcaag aacaactttt tgatcaggta gcaagcttgt tggaagaacg agaaattgtc
     7441 actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac tggtttagat
     7501 atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga tattgttcat
     7561 aatctagctg agaaagtggt ggttgttcga ttagaaaaac cagtaacttt tcacaatatg
     7621 atagctcctg ataaggaagt agaagtatcc ctactcttct ttattattaa caattcaagt
     7681 tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa tggacatctt
     7741 gaagacctat caaaaatttc cgaaccagaa aaactttatg cttacattgc tgaagcaacc
     7801 gcttaatctt gtctattaaa aaataaaatc ggaggaaatc caaatgatta aaattcttgc
     7861 tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag aagaagaact
     7921 ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg taaacgaaga
     7981 ccttatgaaa ggttacgata tctttacacc aatcgctgca acagaccttg gttttgaacc
     8041 aggtatccca gttatcgaag ctgggccaat cttattccgt atcccagcaa tgagcgctcc
     8101 agtatttgac aatattgaag cagctattaa agaacacgga ttaagctaat tctaatttgt
     8161 taacattcat ataacataaa aaagggagga actgttatgg atgcaatctt tgacctaatc
     8221 ggaaaggttt tcaatcccat cttagaaatg ggtggacctg tcatcatgtt gatcattttg
     8281 acagtattgg ctttactttt tggagtgaaa ttctccaaag cgcttgaagg tggtatcaaa
     8341 cttgccatcg ctcttacagg tatcggtgct atcatcggta tgctaaacac tgctttctca
     8401 gcatcacttg caaaattcgt tgaaaacact ggtatccaat tgagtattac cgacgttggt
     8461 tgggcaccac tcgcaacaat cacttggggt tctgcttgga cactatactt cttgctcatc
     8521 atgttgattg tcaacgtagt gatgcttgct atgaagaaaa ccgatacact tgatgtcgat
     8581 atctttgata tctggcactt gtctatcaca ggtctcttga ttaaatggta tgctgataac
     8641 aatggtgtga gtcaaggggt ttcactcttt attgctacag cagctatcgt ccttgtcggt
     8701 gtgttgaaaa ttatcaactc tgacttgatg aaacctacat ttgatgacct tcttaacgcc
     8761 ccaagttcat caccaatgac atcaactcac atgaactaca tgatgaaccc agttatcatg
     8821 gttttggata agatttttga aaaattcttc ccaggccttg ataaatatga ctttgatgct
     8881 gctaaattga acaagaaaat cggtttctgg ggatctaaat tcttcatcgg tttcatcctt
     8941 ggtatcgtta tcggtattat gggaactcca catccaattg caggtgttgc agatgcagat
     9001 aaatggcgtc ttgttatcaa aggatggttg tctcttggtt tgactgccgg tgtatctttg
     9061 gaactcttct cacttatcgg ttcatggttc atcgcagccg tagaaccact atcacaaggt
     9121 attacaaacg ttgctactaa acgtcttcaa ggacgtaaat tcaatatcgg tcttgactgg
     9181 ccattcatcg ctggtcgtgc tgaaatctgg gcttgtgcca acgtacttgc accaatcatg
     9241 ttgattgaag cagtgcttct ttcaaaagtt ggaaatggta tcttgccact tgcaggtatc
     9301 atcgctatgg gtgttactcc agctctcttg gttgtaactc gtggtaaatt gctccgtatg
     9361 attatcttcg gaacactctt gttgccactc ttccttcttt caggtacact tattgcacca
     9421 tttgcaacag aacttgctaa aggtgtaggt gccttcccag aaggtgtgag ccaaactcaa
     9481 ttgattactc actctactct tgaaggacca atcgaaaaac ttcttggttg gacaattggt
     9541 aacactacaa ctggtgatat caaagcaatc cttggtgcag tagtcttcct tgtattctat
     9601 atcggtatct ttgcttggta cagaaaacaa atgatcaaac gtaacgaaga gtacgcaaca
     9661 aaagcaaaat aatgcgctcc tataaaatat aaacttaatg aaaatcaaag agcaaactag
     9721 gaagctagcc gcaggttgct caaaacac
//
LOCUS       DBEJZJ010000052         9104 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000052 DBEJZJ010000000
VERSION     DBEJZJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.52"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(64..971)
                     /locus_tag="ACL3R8_001845"
                     /pseudo
     CDS             complement(64..971)
                     /locus_tag="ACL3R8_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            1227..3860
                     /gene="polA"
                     /locus_tag="ACL3R8_001846"
     CDS             1227..3860
                     /gene="polA"
                     /locus_tag="ACL3R8_001846"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR1314672.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3945..4382
                     /locus_tag="ACL3R8_001847"
     CDS             3945..4382
                     /locus_tag="ACL3R8_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR1314673.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(4565..5575)
                     /locus_tag="ACL3R8_001848"
     CDS             complement(4565..5575)
                     /locus_tag="ACL3R8_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR1314674.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            5724..6893
                     /locus_tag="ACL3R8_001849"
     CDS             5724..6893
                     /locus_tag="ACL3R8_001849"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR1314675.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6890..7660
                     /gene="recO"
                     /locus_tag="ACL3R8_001850"
     CDS             6890..7660
                     /gene="recO"
                     /locus_tag="ACL3R8_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR1314676.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            7657..8649
                     /gene="plsX"
                     /locus_tag="ACL3R8_001851"
     CDS             7657..8649
                     /gene="plsX"
                     /locus_tag="ACL3R8_001851"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR1314677.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            8655..8888
                     /locus_tag="ACL3R8_001852"
     CDS             8655..8888
                     /locus_tag="ACL3R8_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR1314678.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            8934..9104
                     /locus_tag="ACL3R8_001853"
                     /pseudo
     CDS             8934..9104
                     /locus_tag="ACL3R8_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         2580 a         1714 c         2262 g         2548 t
ORIGIN      
        1 acacaaaata ggctccataa tatccatagt gggtaaatcc cctatggata ttatggagcc
       61 attttacaac agtgcctcaa attcagatac tgacatacct aattgctggc tggcaacctc
      121 agaagtcaga agaccttggc gtactatgtc taggaaggca aaaagtttcc tttctgccct
      181 tccttcaact ttcccacgct ctagtccttg ttcaaggcct tcagccctag cagtttccaa
      241 ggcatagtcc tgtgctaaca agacttgttc ttctcgcata tgtagttgac taaacatttt
      301 cctgtcctcc tcggaccagc tcttgtagtc cagcagttga tttgcttggg taatggctcg
      361 ttgcggttgc tgggtaaagg gcttgttgcc gaaaaactcc aaccatggct tgcgaacctt
      421 gtctttgctg gtttctctgt attttttaat tccaagaatg ccatcttaac cagatggttt
      481 tcctgtccat tgttggtaat cgccaatacc tcacctgttg tgtcttcgcg catactaaag
      541 ctatgaaaag ccaggtcatc tgagaaataa ttactatcca cgatagcaat gacgtaaaca
      601 ggagcgatgt gtttgtagat ctagtgagta tcaccttctc gctgacgaat tttttcaaga
      661 ttttgattaa cctgactgca caggtaagcc cacaagtgat tgatgaaaaa attctgatga
      721 tggacttgaa tctcaataat tacttgagta ccgttatcca actccgccaa gacgtctata
      781 ctggtataaa aatcctgcac cgagtaaggc atggagagta atacgtgaat atcgcttccc
      841 tccaaaatgg tcacattttt tgctggcaag tccagcatat cgcgaataaa ttgacaagtg
      901 atttctggat tgctgaatat tttcttagca atcaaatcat tagttgggct gatgcccgga
      961 tgtctgagaa tcctcctatt cctccttcta tagtgagttg aaataagatg tgaataactc
     1021 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gtcaaggtgt actattatag
     1081 attcaatata ctatattata gcacattttt aaatctaggt ttactaaatt ctctggctct
     1141 atctatttat tcggaaaaag tttgaaaaat acttgctcta gctcttccca atggtatttt
     1201 ttgattcttt cctttataat gggtgtatgg ataagaaaaa attattattg attgatgggt
     1261 cttctgtagc ttttcgggcg ttttttgcgc tgtatcagca gttggaccgt tttaagaatg
     1321 cggctggttt gcataccaat gcgatttatg gttttcagtt gatgttgagt catttgttgg
     1381 agcgggttga gccgagtcat attttggtgg cttttgatgc gggaaagacg accttccgga
     1441 cagagatgta tgcggactat aagggtggtc gggccaagac tcctgatgag tttcgtgagc
     1501 aatttccttt cattcgtgag ttgctggatc atatggggat tcgtcactat gagctggctc
     1561 agtatgaggc ggatgacatc attgggacgc tggataagct agcagagcag gatggttttg
     1621 atattaccat tgtcagtggg gacaaggatt tgattcagct gacggatgag catacggtgg
     1681 ttgaaatttc caagaaaggt gtggctgagt ttgaggcctt tacgccagat tacctcatgg
     1741 aagaaatggg cctcacacca gctcagttta tcgatctcaa ggcgctcatg ggtgataagt
     1801 cggataatat ccctggggtg accaaagtcg gtgaaaagac gggtattaag ctcttgctgg
     1861 agcatggttc gcttgagggg atttatgaaa atattgatgg aatgaagact tctaagatga
     1921 aggaaaatct catcaatgac aaggaacagg cctttttgtc taaaacacta gcgaccattg
     1981 ataccaaggc accgattgcg attggtttag aggacttggt ctatagtggt ccagatgttg
     2041 aaaatcttgg gaaattctac gatgagatgg gcttcaaaca gctaaagcag gctttaaatg
     2101 tgtcgtcagc tgatgtgtct gagagtttgg attttactat tgttgaccaa atcagtcaag
     2161 atatgctgag tgaagagtct atcttccact ttgagctttt tggtgagaat taccatacgg
     2221 ataatttggt tggatttgcc tggtcttgtg gggataagct ctatgccaca gacaagcttg
     2281 agctgttgca agacccgatt ttcaaggatt tcttagaaaa aacatctctg agagtttatg
     2341 actttaagaa ggttaaagtt cttttgcaac gttttggtgt ggatttgcag gcgcctgctt
     2401 ttgacatccg tttggctaaa tacctccttt cgactgtgga ggacaatgaa attgcgacca
     2461 tcgctagtct ttatggtcag acttacttgg ttgatgatga aactttctac ggtaagggtg
     2521 ttaaaaaggc cattcctgaa cgtgagaaat tcttggaaca cttagcttgt aaacttgctg
     2581 ttttggtaga aacagagcct attttacttg aaaaactcag cgaaaatggg caattagagc
     2641 ttctttatga tatggagcaa cctctggctt ttgtccttgc caagatggaa attgctggga
     2701 ttatggtcaa gaaagagacc ttgcttgaga tgcaggctga aaatgagctt gtcattgaaa
     2761 aactgactca agagatttac gagctggctg gtgaggagtt taatgtcaac tcgcctaagc
     2821 agttgggcgt gcttctcttt gagaaattgg gacttcctct agaatacact aagaaaacca
     2881 agacaggtta ttcgacagca gtggatgttt tggagcgtct cgctcctatt gctccgattg
     2941 ttaagaaaat cctggattac cgtcaaattg ctaagattca atctacttat gtaattggct
     3001 tgcaggactg gattttggct gatggaaaga ttcatactcg ctatgtgcag gatttgaccc
     3061 agaccgggcg tttgtctagt gtggatccaa acttgcaaaa tattcctgcc cgattggaac
     3121 aggggcgctt gattcggaag gcttttgtgc cagagtggga ggatagtgtg ctactcagct
     3181 ctgactattc acagattgaa ttgcgcgttt tggcgcatat ttctaaggat gagcacttga
     3241 ttaaggcctt ccaagagggg gcagatatcc atacttcgac agccatgcgg gtctttggca
     3301 ttgagcgtcc tgatgatgtg actgcaaacg accgtcgcaa tgccaaggca gttaactttg
     3361 gagtggttta tgggatttca gactttggct tgtctaataa tttgggaatt agtcgtaagg
     3421 aagccaaagc ctacattgat acctactttg aacgttttcc aggtattaaa aactacatgg
     3481 atgaagtggt gcgggaggcg cgtgataagg gctatgtaga gaccctcttt aagcgtcgcc
     3541 gtgagttgcc agatatcaat tcgcgcaact tcaatattcg tggttttgcg gaacgaactg
     3601 ctatcaactc acctatccag ggttcggcag cagatattct caagattgcc atgattcagc
     3661 tggataaagc cttggttgca ggtggttatc agactaagat gctgttacaa gtgcacgatg
     3721 aaatcgtcct tgaagtgcct aaatctgaat tggtagagat gaaaaaattg gtgaaacaaa
     3781 ccatggaaga agccattcaa ctcagtgttc ctcttatcgc agatgagaat gaaggggcaa
     3841 cctggtacga ggctaaataa aaagggggct agtcctcctt ttttgtagta taattctgca
     3901 aaccttttca aaatgtgcta tactgatgaa aaaggaggat ttctatgagt caagaattta
     3961 tcaatccaag tgatggcgtg attcgtcagt atctcgcaac gagtaaaacc cttgctgtgg
     4021 tgggtttgtc tgaccgtgaa gaaacaacca gcaatcgagt aacaaaggaa atgcaggctc
     4081 ggggctataa aatcatccca gtcaatccca aggcggcagg tggcgaaatc ttgggtgaaa
     4141 aggcttatgc tagcctcgct gaaattcctt ttcctgtaga tattgtcaat gtttatcgtc
     4201 gcagtgaatt tctgcccgat gtggcgcgtg attttctcaa agctgatgcc aagatttttt
     4261 gggcacagct aggacttgaa agtttagaag cgaaagagat tttgcgtgat ggtggatgtg
     4321 atgatatcgt gatgaatcgc tgtatcaaga gagaacatac tcgcttgatt gaggaagcat
     4381 aagaaaaagg tagctgatgg gctacctttt gtgttatact caatgaaaat caaagagcaa
     4441 actaggaaac tagccgcggg ctgctcaaaa caccgttttg aggttgcaga tagaactgac
     4501 gaagtcagta acatatatac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag
     4561 agtgttagaa aatgccgata agggtctgca taccaagagt ggtgaggatg atggcaatcc
     4621 agcagatggc tccaagaaga atggattttc cactggattt gaccatagcg accagattgg
     4681 ttttgagacc gatagcactc atggccatga caataaggaa tttagagagt tctttgagag
     4741 gagtaaagaa actactggac acacctagag aggtgagtag tgtagtgagg agagaggcaa
     4801 ggataaagta aaggataaaa agtgggaaga cttttttcag ttgcaggctt tgcttgtttt
     4861 cttgttggcg actttgccag taggatagaa agagcgtgat agggataatg gccaaagtac
     4921 gtgtgagttt aacaatggtt gcagactcga gggtattgct ttggtaaaga ctgtcccaag
     4981 cgctggcggc agccgttaca gaggaagtgt cgttgaccgc agtccctgca aagagggcga
     5041 agccttcatt ggatagatga agccaggtgc cgagggttgg aaagatgagc gcagccaaga
     5101 cattgaagaa aaagataacg gaaatggctt gggctacttc cttttcctta gcatcaataa
     5161 cgggcgctgt cgctgcaatg gcagaacccc cacagataga agaacctact ccaaccaagg
     5221 tagccagttt tgtatccagg gcaaagaaac gctggaagag gtaggcaata atcagagcta
     5281 ttgagatagt ggacaggatg acagggagtg aagattggcc aactgcgaag acctgcgaga
     5341 tattgagacc aaaaccaagc aagacaacgg catattggag caacttcttg gaactaaagg
     5401 tcaaaccagc atccagttgt ttataggacg agagaaaggg atgtaggagc atgcctatga
     5461 aaatggcaaa aacgggcgcg ccaatcacag ggaagaatcc tcctaagtac caagatacga
     5521 tagaaatgag aaggcaggcc aagatacctg ctccattttt tgatagaaat gacataaaaa
     5581 cctccaaata aaatctatta ccattataga cctataaaca ggaaaagtaa aatagaaagt
     5641 ggaaagctat cctctaatgt atttttgcgg tcggggggct tttgtagtat aatagagata
     5701 cgttttgaaa gtaggaggta tctatggact taactaagcg ctttaataaa cagttagata
     5761 aaattcaagt ttcgttgatt cgtcagtttg accaggctat ttcggagatt cctggggtct
     5821 tgcgtttgac cttgggggaa cctgatttta caacgccaga ccatgtcaag gaggcggcca
     5881 agcgagcgat tgatcagaac caatcctact atacagggat gagtggtctg ctgactctac
     5941 gtcaggcagc tagtgacttt gttaaggaaa agtaccaact ggactatgct cctgaaaatg
     6001 aaatcttggt tacaattggg gcgacagagg ctttatctgc gactttgacg gctattttgg
     6061 aagagggaga caaggtactt ttgccagctc ctgcttatcc aggctatgaa ccgattgtta
     6121 acttagttgg ggcagaaatt gttgagattg atacgactga aaatggtttt gtcttgactc
     6181 ctgagatgtt ggagaaggcc attttggagc agggtgataa gctcaaggcg gttattctca
     6241 actatccagc caatccgaca ggaattacct acagtcgaga gcagttagag gccttggcag
     6301 ctgttttacg caagtacgaa atttttgttg tctgtgatga ggtttactca gaattgacct
     6361 acacaggcga agcccatgtg tctctaggaa cgatgttgag agaccaggct attattatca
     6421 atggtttgtc taaatcgcat gccatgacag gttggcgttt ggggctgatt ttcgctcctg
     6481 cggccttcac atcccagtta atcaagagtc accaatactt ggtcactgcc gcaaatacca
     6541 tggcgcaaca tgctgcggta gaagccttga cggctggtaa aaatgatgcg gagcccatga
     6601 agaaggaata tatccagcgt cgggactata tcatcgaaaa aatgactgct cttggttttg
     6661 agattatcaa accagacggt gccttctata tttttgctaa aattccagcg ggctacaatc
     6721 aagactcctt tgcttttctg aaggattttg ctcagaagaa ggccgttgcc tttatccctg
     6781 gtgcagcctt tggacgttac ggggaaggct acgtccgcct atcttatgca gccagcatgg
     6841 agactatcaa agaagccatg aaacgacttg aggagtatat gagagaagca tgattcagtc
     6901 tatcacgagt caaggcttgg tgctttacaa tcgcaatttt cgtgaggatg acaagcttgt
     6961 caaaattttt acagagcagg ttggcaaatg catgtttttt gtcaaacacg ctggtcagtc
     7021 taagctggcg cctgttattc agcccttggt gctggcacga tttctcttgc gaatcaatga
     7081 tgacggactc agttacatcg aagactatca tgaggtcatg acttttccca agattaatag
     7141 tgacctcttt gtcatggcct atgcgaccta tgtggcagct cttgcagatg ctagtttgca
     7201 ggacaatcag caggatgctc ccttgtttgc ttttttgcaa aagactttgg agttgatgga
     7261 agcaggcttg gattatcagg ttttgaccaa tatttttgaa attcaaattt tgactcgatt
     7321 tggaatcagc ctcaatttta atgagtgtgt cttctgccat cgggttggtc aggcttttga
     7381 cttttctttc aaatatggag cctgtctctg tccagagcat tatcatgagg atgagagacg
     7441 ttgccatctc aatcccaata tcccctatct gctcaatcaa tttcaagcta ttgattttga
     7501 gactttggag accatttcgc tcaagcctgg aatcaagcaa gagctacgcc aatttatgga
     7561 tcaactatat gaagagtacg ttgggattca cctaaaatca aagaaattta ttgattccct
     7621 agcagactgg ggacaattac taaaagagga aaagaaatga aaaaaatcgc agtagatgcc
     7681 atggggggcg attacgcacc tcaggccatc gttgagggtg tcaatcaagc cctatctgac
     7741 ttttcagata tcgaggttca actctacgga gatgaagcta aaatcaagca atatctgaca
     7801 gcgacagagc gcgtcagcat tatccatacg gatgagaaga ttgattcgga tgatgaacct
     7861 acgagagcta ttcggaataa gaaaaatgcc agtatggtat tggcagccaa ggctgtcaaa
     7921 gatggtgaag cagacgctgt cctttcggct gggaatacag gtgctttgtt ggctgctgga
     7981 ttcttcatcg tgggtcgtat caagaatatc gaccgtcctg gacttatgtc aacattgccg
     8041 actgtagatg ggaaaggttt tgacatgctt gacctcggtg ctaatgcaga aaatacagcc
     8101 cagcacctcc atcaatacgc tgtcctaggt tctttctatg ccaagaatgt tcgtggcatt
     8161 gcgcaaccac gtgttggttt gctcaacaac ggaacagaga gtagcaaggg cgacccgctt
     8221 cgtaaggaaa cttatgaatt actggcggct gatgaaagtt tgaactttat cggaaacgtg
     8281 gaagcgcgtg atttgatgaa tggtgttgca gatgttgttg tggcagatgg tttcacggga
     8341 aacgctgtgc tcaaatccat cgaagggaca gctatgggaa tcatgggctt gctcaagaca
     8401 gctattacag gtggtggtct tcgagcgaaa ctaggtgccc tccttctcaa ggacagcctc
     8461 agaggtttga aaaaacagct caattattca gatgttggtg gagcggtctt gtttggtgtc
     8521 aaggcacctg ttgtcaagac tcatggctca agcgatgcca aggctgttta tagtacgatt
     8581 cgccagattc gtaccatgct agaaacagaa gtagttgccc agactgcgcg tgaattttca
     8641 ggagaataaa agagatgaaa gaaaaagaaa tttttgacag tattgtgacc attatccaag
     8701 agcgacaggg agaggacttt gtcgtgacag aatccttgag tctgaaagac gacttggatg
     8761 ctgactcagt tgatttgatg gagtttatct tgacgctgga ggatgaattt agtatcgaaa
     8821 tcagcgatga ggaaattgac caactccaaa gtgtaggaga tgtggttaaa atcattcaag
     8881 gaaaatagca atcggagttc caagtcaacg gaagtagatg gtttttagaa atgagaaata
     8941 tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc
     9001 ctcaagcaca aacttccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa
     9061 gcctgtaatc atgcgctatc taaggagaga agcaaggttg agaa
//
LOCUS       DBEJZJ010000053         8943 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000053 DBEJZJ010000000
VERSION     DBEJZJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.53"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..109
                     /locus_tag="ACL3R8_001854"
                     /pseudo
     CDS             1..109
                     /locus_tag="ACL3R8_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(246..1214)
                     /locus_tag="ACL3R8_001855"
     CDS             complement(246..1214)
                     /locus_tag="ACL3R8_001855"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR1314679.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1359..2173)
                     /locus_tag="ACL3R8_001856"
                     /pseudo
     CDS             complement(1359..2173)
                     /locus_tag="ACL3R8_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2198..2695)
                     /locus_tag="ACL3R8_001857"
     CDS             complement(2198..2695)
                     /locus_tag="ACL3R8_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR1314680.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2768..4129)
                     /gene="radA"
                     /locus_tag="ACL3R8_001858"
     CDS             complement(2768..4129)
                     /gene="radA"
                     /locus_tag="ACL3R8_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR1314681.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGMTTIQEVLKK
                     VFA"
     gene            complement(4143..4658)
                     /locus_tag="ACL3R8_001859"
     CDS             complement(4143..4658)
                     /locus_tag="ACL3R8_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR1314682.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4660..5103)
                     /locus_tag="ACL3R8_001860"
     CDS             complement(4660..5103)
                     /locus_tag="ACL3R8_001860"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR1314683.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(5163..5256)
                     /gene="ffs"
                     /locus_tag="ACL3R8_001861"
     ncRNA           complement(5163..5256)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3R8_001861"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5289..5756)
                     /gene="tadA"
                     /locus_tag="ACL3R8_001862"
     CDS             complement(5289..5756)
                     /gene="tadA"
                     /locus_tag="ACL3R8_001862"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR1314684.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5957..7243)
                     /locus_tag="ACL3R8_001863"
     CDS             complement(5957..7243)
                     /locus_tag="ACL3R8_001863"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR1314685.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7474..7710)
                     /gene="comW"
                     /locus_tag="ACL3R8_001864"
     CDS             complement(7474..7710)
                     /gene="comW"
                     /locus_tag="ACL3R8_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR1314686.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7975..8748
                     /locus_tag="ACL3R8_001865"
                     /pseudo
     CDS             7975..8748
                     /locus_tag="ACL3R8_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8867..8940)
                     /locus_tag="ACL3R8_001866"
     tRNA            complement(8867..8940)
                     /locus_tag="ACL3R8_001866"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8904..8906),aa:Asn,seq:gtt)
BASE COUNT         2870 a         2140 c         1423 g         2510 t
ORIGIN      
        1 accttctaaa attccttatc ttgaaacgac tggtatacct actagaattc tccttagaaa
       61 gcgtcgattc aagtgctatc actgttcaaa aatgatggtc gctgaaactt ctgatgacgt
      121 acagtcatat ttcttctctt tttattatat cacagtttta aatctagctt tactagattc
      181 accgctacta tctatttatt cggaaaaaag acgaaaaaac ctgagaatca tctcaggctt
      241 ggtcattaaa tttttttctc aatatcgaaa agtggagaaa gtggtcgttt ttcatgaata
      301 cgtacgatag catcccctag gagatgagcg attgaaatct gctcaatctt atcaatcaaa
      361 cgctcttctg gcagatagat ggtatccaaa acaaccaatt tcttaatagc tgatttttgg
      421 atattgtccg tagcaggacc agaaagaact gggtgcgtac agcttgcata gacttcaaca
      481 gcaccagctt ccgcaagagc atctgccgca tgacaaatcg ttccagcggt atcaatcata
      541 tcatcaatca agatacaagt cttgccttca accttaccga tgatgttcat aacttcacta
      601 gtattcatct tatcaacgct acgacgttta tcaataatag cgatagatgt tttcaaaaat
      661 tctgccaact tacgagcacg agtcacccct ccatggtccg ggctgacaac cacatagtca
      721 gaaccaacca taccacgacg ctcaaaataa tctgcaatca gaggagcacc catcaaatga
      781 tccacaggaa tatcaaagaa tccttgaatt tgcgcagcat gcaagtcgat ggtcaataaa
      841 cgatccactc cagctacttc aagcatattt gcgacaagtt ttgaagtgat tggctcacgc
      901 gctctcgcct ttctatcctg acgtgcatac ccatagtaag gcatgacaac attaacagat
      961 tctgcactcg cacgcttcaa agcatctacc ataatcaaaa tttcaagcag attgtcattt
     1021 acaggcgaac tagttgattg taagataaag acgtgtttcc cacggattga ttcttcaatg
     1081 ttgacctgaa tctctccatc tgaaaattgg cgaacacttg atttccccaa ctctatccca
     1141 atctcctgcg ccacacgttc tgccaattct ttattagaag aaagggcaaa cagctttaaa
     1201 tcagaaaaag acatgatttc ctccggtata tatgtataac ttgtgctttt cacaagattt
     1261 tccatctacc attgtagcgc tttttgcact atttttcaat caaaaataaa agaagggcac
     1321 catatttgta cccttgcatc attcttttga aaaatattct aggtcatcaa ctcattgtgt
     1381 ttctcaacaa agcaataagc atgataaaaa ccatagagag caatagccgt aaccactgga
     1441 atcgctaaag gcaactctgt ttccaactcc acaaaaggag agttaaacaa gaagtgagtt
     1501 cccaaggcta aacctagaaa aataagtccc tgtttcttgc caaccttctg tcctttatag
     1561 gctctgtaaa gcaagtaaac acctactaca gctagacctg aaaaagtcca gtgagaggca
     1621 attcctgaga tgatacgctc taaaattcgc gaaatagtaa agtcaaagcc ctctggcaaa
     1681 tccgtacgaa tataaccaat atcctcaatc atttggaatc ccaaaccgga agcaattcca
     1741 agtaaaaaca aagattttaa ttttcgcaca ggaatcaaag ccaaaacaaa aacaagtggc
     1801 aataatttca agggttcttc taccaaagga gccacaatag cactttcaaa ggcatttaaa
     1861 aatgtactat ctgggaaaag aacccccagt aaatcatgga tataagtatt agcaaaacta
     1921 gacaaccatc ctgaaaggaa catccctccc aataaagaca gaatcaaaac cttctttggc
     1981 aattcccatt tttcccaata cggaagagaa aataaagagc cggaatcatg taaaagagag
     2041 ctagaaagat agaaattccc attagtccat attccgcacc tgacctcgaa ccgtccgtat
     2101 agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata aataaaatac
     2161 tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg actgtcatac
     2221 ttcctgtatc aacattgtaa atagcaccag agataatgac atcgtctggt attaggggag
     2281 actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg aagggcaaga
     2341 agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga aaaggttcat
     2401 tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct cttgtcccca
     2461 tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga ccacctgcat
     2521 tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg tgcagacgag
     2581 agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga tttaactgcc
     2641 catgtagggc aacataagcc tgattggctt gcataaactg ttcaaaatac gacacgattc
     2701 cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta agagaatttg
     2761 tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcatg ccaatgacct
     2821 gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa atcttagtaa
     2881 agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc cgaatctctc
     2941 ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggtttg tctttgtagc
     3001 tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat ttaacaccac
     3061 cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt ttttccaaaa
     3121 cagccataat caagctagca cggttaaaat caagtcctgt cgtagtacgc ttggcatttc
     3181 caaacatggt cggtgttact aaagcctgaa cctccgccaa aatcggacgc gtcccttcca
     3241 tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg aaaacttgac
     3301 tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca atctcattag
     3361 tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga cgctcccctt
     3421 caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc aaggttcctt
     3481 ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc aactgcatga
     3541 gttcagcggt cacttcacgt acctgagaaa cagacccctg cacccctgaa atctcaggag
     3601 acatgatggt ctggatggaa tcaataataa gaaagtctgg ctggatacgc tccacttctg
     3661 cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca atatcaccta
     3721 agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca tagagaactg
     3781 tccccacttg ggacaactgg gttgagactt gttggagaag agttgatttc ccaatcccag
     3841 gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc acacggttga
     3901 attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca gctagtttca
     3961 tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg gcaacctcaa
     4021 cctcttccac aaaagaagac caagatccac agttggggca acgtcccaga tatttagggg
     4081 aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg acaaacctct
     4141 tcctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc atttggcaca
     4201 aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc tcgatactta
     4261 gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg aataggacta
     4321 ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc aaagttttct
     4381 attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa aggaagaccc
     4441 gtagcacaga ccacatacga agccgtttct aaagctcttg tgactgcaga agatacgatt
     4501 atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg ccgtcccatc
     4561 tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc taactcacgg
     4621 taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg tcgatccaaa
     4681 tccaccagtt cgaacgccac cagctgcatc tccatctgca attaagaaag tagcaaaaac
     4741 agcctggaca atacgttccc caacttcaag aacaacctct tggtctgtga tattcttcat
     4801 ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat caatgacccc
     4861 aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat catagaggta
     4921 gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga caatctctcc
     4981 tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat gcgctgtctc
     5041 acgcttgggc aataaatttt catctgtaaa acttgaaacc aattcaaaac cacgaatttt
     5101 cataattttc tcttttctat tatcatttat tctagattat tctatcttat ttattcggaa
     5161 aaagcacgaa aaaagagcac acaattcaaa tcgcttaggg ctgctggatt cctcccctga
     5221 cccgcttcac gcagaactgt tgctccacta tttattatat cacattccta ttcattttaa
     5281 aagcaaaatt attttttccg tctatttcta aaaaaatcct gcatgatagc tgcgcattca
     5341 tcttccaaaa ttcctatttc aacctccaca cgatgattga gacgctcatc tgtcaagata
     5401 ttgtacaaac tcccagcagc gccaaatttc tggtttttag ccccatagac cacatttgga
     5461 atgcgggcaa gcccaatcgc tccactacac atgacacaag gttcaatggt cacaaaaagt
     5521 gtgcaatcca gcaagcgcca gctctcctca ctcaagttcg catcctctat agccataatt
     5581 tccgcatgca taaccgctcg ctgtaattcc tcacgcgcat tatgcccacg accaatgatt
     5641 tccccatctt tgacaatcac acaaccaatt ggaatttcat cgtgttcaag agcaatctca
     5701 gcctctctca aagcctccct cataaagact tctttttctt caagcgtata atacatctct
     5761 tttctctttt cctacttatc gattttatta ttatatcatg aatcccaaca caaaaaaagc
     5821 caccgaatgc ggtgactcta tagggagatt attatgaaaa agaaaagttt aggatatttg
     5881 ttacaacaag ttaggaggtc ttcttgtaac cgtctatagt atacccgacc tatcttaaac
     5941 aaatcttaaa aatctcttag gaccaaacac tttctaaaat atttgtttgt tcacgaccag
     6001 gacctactga gaaagtagaa atacgaacgc caaccaattc actcacacga cgaacatagt
     6061 tacgcgcatt ctcaggaaga tcttccaaat tgcgaactcc ggtaatatct tctgaccaac
     6121 ctggcaactc ttcatagata ggcttgcaac gtttcaattg ctcaagacta gctggatagt
     6181 agtcaatacg ttgaccgtca agatcatagg ccacacagat tttcacagta tccaaaccgc
     6241 tcaaaacatc aatagagttc aaagaaaggt tagtaatacc agaaacacga cggctatgac
     6301 gcatcacaac tgagtcaaac caacctacac gacgtggacg accagttgtt gtaccatact
     6361 catgacccac ttcacggata cgttctccca cttcatcaaa caactcagtt gggaaaggac
     6421 catctcctac acgactcgta taagctttac atacacctac aaccttgtca atcttgcttg
     6481 gaccgacacc agaaccaatt gtcacaccac cagctacagg gtttgatgac gtaacaaatg
     6541 gataagtacc ttggtcgata tctagcataa caccttgtgc accttcaaaa agcacacgtt
     6601 tgccattatc aagcgcatca ttcaagataa cagatgtatc tatcacgtat ttcttgattt
     6661 gttgaccata ttcgtaatat tcttcaaaaa tatcatcgaa aacaatcgct ttactgtcat
     6721 acaatttttc aaaaagacga ttcttttcag caaggttacg ttctaaacgc tcacggaaaa
     6781 tatctttatc taaaagatct gcaatacgaa ttccaacacg agcagccttg tccatataag
     6841 ctggaccaat tcccttaatt gtcgtaccaa tcttattgtc gcccttagct tcttcttgca
     6901 agcgatccaa ctcgatatga taaggcaaaa taacatgcgc acgatcagaa atacgcaagt
     6961 tatcagttgt tacaccttcc tcatgaagat agctcaactc ttttacaaga gatttaggat
     7021 ttacaaccat accattccca atgacagata ttttttcagg gaagaaaatc ccagatggaa
     7081 tcaagtgcaa cttaaatttc ttaccgtcaa tcacaatcgt gtgaccagca ttatcaccac
     7141 cttggtaacg tgcaatcact tctgcattcg ctgaaaggaa gtctgtaatc ttccctttac
     7201 cttcatcacc ccattgggta cctacaacaa caactgaagt cataatcttg tctgagccct
     7261 caggctcttc ctttctcaca tacatggcag gactctcacc tgcaattata tcttacaatt
     7321 tattataata aaaaatcgcc tttttatcaa gaagaaacaa tagaaagatt tgctatttcc
     7381 aactattaaa aaatgattta gaaaaattac tagctattta ctatcatctt tccataaaag
     7441 agtaaattag ttcggaaatt tactaaaatt acctcaacaa gaaataaaac cccgattcat
     7501 taccaatttt tcaagataca aacgataagc aacacgataa tggtaaacga taaaatccct
     7561 acgacaacca atgccatatc tcactaaata ataaattaaa aatttaaaat gaacatgttc
     7621 ccagtcaaaa ttatcaccaa atgtaggacc atactcttct tcaatactat catagaaatt
     7681 agccatctgc tcataaattt tttgtaacat aatcaaatac tccttttctt ttttataaac
     7741 ttattctaac aaaaaatttt acacattcac tatcaattcc tgaattgtta aaataccagg
     7801 ctcaacaaga taaaaatagg aaaagttgac agaatagaaa caaatttgct acctaaattt
     7861 caaacgatta aagttctaaa aagaccgcct taaaactttt gggtaaatcc tattagaact
     7921 ataatatttt tatataggta ttatggttct gattttctag tataaaaaat tcaaactaga
     7981 attcttctta gaaaaggccg ttttaagtgc tatcactgtt caaaaatgag ggtcgctgaa
     8041 acttctatcg tcaagaagaa tcatcaaatt ccttgtatca tcaaccaaaa gattgctcag
     8101 aagctaatta aaaagacttc tatgaccgac attgatcatc agttgtctat ttcaacttca
     8161 actgtcattc gcaagatcaa tgattttcac tttgagcatg atttttcgcg tcttcctgag
     8221 attatgtcct aggacgttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga
     8281 tgagctttat tgctcaagac tttgataagc tcaatatcat aactgttctt gagagcagaa
     8341 cacaagccat catccgaaat cccatgaata caaggctatc aagcgatact gaaagctcat
     8401 tcaacaagat agtcagaaac tgagtgataa acgattttat cgccctactt ttcgtatgca
     8461 cttgactaat aaagaaattc tagataaact tttgagctat tccgaagact tgaaacacca
     8521 ctataatctc tatcagctct tgcttttcca cctctttttc agactctgtt taaaaccttc
     8581 ctcaaagata aagaaaaaat cgtcaacggc cttcaattac cttattccaa cgccaaactg
     8641 gaagccacca ataatctcat caaacttatc aagtacaatg cctttggttt taggaacttt
     8701 gaaaacttca aaaaagaaag gacgaaattt gtcctttctc aagcttagct tttcttcaac
     8761 ccactacagt tgacaaagag ccactatttt tggttcattt tactataaca cgaaatagat
     8821 tattattaca taataaaaaa gaggtctaaa cctcttaact aaattactcc gccagtagga
     8881 ctcgaaccta cgacatcatg attaacagtc atgcgctact accaactgag ctatggcgga
     8941 tta
//
LOCUS       DBEJZJ010000054         8895 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000054 DBEJZJ010000000
VERSION     DBEJZJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.54"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            179..1672
                     /locus_tag="ACL3R8_001867"
     CDS             179..1672
                     /locus_tag="ACL3R8_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR1314687.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1685..2212
                     /locus_tag="ACL3R8_001868"
                     /pseudo
     CDS             1685..2212
                     /locus_tag="ACL3R8_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2224..2729
                     /locus_tag="ACL3R8_001869"
                     /pseudo
     CDS             2224..2729
                     /locus_tag="ACL3R8_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840532.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2861..3097
                     /locus_tag="ACL3R8_001870"
     CDS             2861..3097
                     /locus_tag="ACL3R8_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR1314688.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3094..3507
                     /locus_tag="ACL3R8_001871"
     CDS             3094..3507
                     /locus_tag="ACL3R8_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR1314689.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            3625..4590
                     /gene="xerA"
                     /locus_tag="ACL3R8_001872"
     CDS             3625..4590
                     /gene="xerA"
                     /locus_tag="ACL3R8_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR1314690.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4613..5194
                     /locus_tag="ACL3R8_001873"
     CDS             4613..5194
                     /locus_tag="ACL3R8_001873"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR1314691.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            5224..8574
                     /locus_tag="ACL3R8_001874"
     CDS             5224..8574
                     /locus_tag="ACL3R8_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR1314692.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYCATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQEIYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISDQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         3050 a         1346 c         1789 g         2710 t
ORIGIN      
        1 gaactgacag agtcagtatc atatacctac ggcaaggtga agctgacgtg gtttgaagag
       61 attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg aagctttgtt
      121 tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa gggaagatat
      181 gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt ggacagaagg
      241 aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta tgaaagattt
      301 ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc cttatgaggg
      361 agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata taggagatgc
      421 tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa atctcaaggg
      481 ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc aaataaataa
      541 acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta ggggattaga
      601 tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct atgaatatct
      661 gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc gtcacatcat
      721 cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag atcccgctat
      781 gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga aagatgaatg
      841 ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg gaaatgatac
      901 ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag tagaaaatcc
      961 acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata aatatacttt
     1021 ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct ctaatgacct
     1081 tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt tcttgcgaac
     1141 tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt ttggttcgtc
     1201 taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg atgctgtaat
     1261 ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca ttctcatctt
     1321 tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga aagcggatgg
     1381 tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag atattatcga
     1441 acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat ctttctttgt
     1501 tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat ataaagagat
     1561 tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa tcaatgattt
     1621 agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt agggaggtgg
     1681 ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt acgcttttaa
     1741 atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc gagatgtaga
     1801 aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc ttattaaaaa
     1861 tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg agggggattt
     1921 agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg tagatgaagg
     1981 ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga ccccttttgt
     2041 tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat tgcctaataa
     2101 actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt atgattttcg
     2161 taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatattccg aggaggtggt
     2221 tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatgtaaa cctcaagatt
     2281 ggtcatctga agggaaagag attatcagaa tacagaatct gactaaaact tcaaaaggga
     2341 taaattatta ttcgggtacg attgataaaa aatacattgt tgaagctggt gatattctta
     2401 tttcgtggtc gggtacatta ggggtttttc agtggtgtgg aagatccgca gtgttaaatc
     2461 agcacatttt taaagtggtt tttgataaga tagatataga taaatcgtat tttaaatatg
     2521 ttgttgaaaa aggtttacaa gatgctgtaa aacatactca tggttccaca atgaaacatt
     2581 taactaaaaa atattttgat aatattatgg tttcatatac aaatttggga gagcaacaaa
     2641 gaattgcaag tgagctggat ttgttaagca agctgatttt aaggagacaa gaacaacttg
     2701 aagagcttaa tctacttgta aaatcacaat tggcaatcca aaaatctctg gaagaacttg
     2761 aaactttgaa gaaatctctg atgcaggagt attttggctg atattctgcc attgtaatta
     2821 cggtaatgat ttgttataat acttcaaagg aggaaatcag atggtagtaa aaacaagaaa
     2881 acaaggaaat tcaatcacca ttacgattcc aagtgaattt aatattccaa gtggtgttaa
     2941 atacgaagcg aaattgttac caagtggtga gattatcttt actcctgaag aattggggca
     3001 gcaggtttct tatgtatctg atgatgcctt tgacttaaat ttagataaaa tatttgacga
     3061 atacgacgat gttttcaaag ctttggtgga aaaatgacaa tctatctgac agaaaagcaa
     3121 attgaaaaaa taaatgcttt agcaattcaa cggtattctc caaatgagaa aattcaaaca
     3181 gttagttctt ctgccttaaa tatgattgtg aacttaccag aacaatttgt ctttgggaag
     3241 tctctttatc caacaatttt tgataaagca acgatactat ttgtccaatt gataaagaag
     3301 catgtttttg ctaatgctaa taaaagaact gctttcttcg ttttggtcaa atttttacaa
     3361 ttaaacggct atcgtttttc tgtaacggta gaagaagcag taaaaatgtg tgtaaccatc
     3421 gcagtagaag ctttaactga tgaaaaaatg acaagctact ccaaatgggt ttctgaacat
     3481 tctgttagag aaaaggtcaa aaagtaacct agtatgctgg atttgaatga gcacaagaaa
     3541 ataaatgaac agacaatatt agaattctgt aatgcagaaa ctgatattgt ctctttttat
     3601 tgatgaataa gaaagtgaga aattatggaa tcaaaagtta caattatcat gcaagaaatg
     3661 ttacctcttt taaataatga acaattacta gcgttgagag agagtttaga acatcatcta
     3721 gtagacggaa aaaagcagca gaagtattcg aataataacc tgttgcaact atttattacc
     3781 gccaagcagg tagagggctg tagctcaaaa acaattcgtt attaccagag gacgattgaa
     3841 aacttgttta atgctattaa agagtctgtg acacaactca caacagatga tttaaggagt
     3901 tatttagcaa attaccagtc tgaaaaggat tgtagtaagg caaatttaga caatattagg
     3961 cgtatattgt cttctttttt tgcttggctt gagcaagagg aatatatcat taaaaatccc
     4021 attcgacgga taaagaaaat taagactgag caaaatgtga aggaaactta tactgatgaa
     4081 catttggaaa ttatgcgtga taactgtgaa aatttgagag atttggcaat aatagaccta
     4141 ctagcatcga caggtatgcg tgtaggggag cttgtacagt tgaatcgttc agatattgat
     4201 tttgaaaaca gagagtgtgt tgtctttggt aaaggaaaga aggagagacc agtatatttt
     4261 gatgctcgga cgaaaattca tttaagaaat tatcttaacg acagaaaaga tagtcaccct
     4321 gctctttttg taacgctagt tggaaaagcc cagagacttg gaattgctgg tgtagagatt
     4381 cgcttaagaa agttaggaga caaactcggc atacaaaagg ttcacccaca taagttcaga
     4441 agaactttag cgactaaggc aattgataaa ggtatgccta tcgaacaagt ccaaaaactg
     4501 ctaggtcata gcaagattga cacaaccctg gcctatgcca tggtcaatca aaataatgtc
     4561 aagcattcac accaaaaatt catctcttaa aagcaaatcc cgatttaacg agatgtttgg
     4621 ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg gtgatagggg
     4681 caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat ttttaaatac
     4741 aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca ctaaaacaaa
     4801 ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga caacaagagg
     4861 tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt tacgtataaa
     4921 ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat ttattatcca
     4981 tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc ctcagttacc
     5041 aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc aaaatgagtt
     5101 cgcagacttt gtagtccagg tcgacaaatc acaatttgct tgtgagatag ctataaaagt
     5161 gtggagaaat agcttgaaat ttagtataat atagctaaac tatttgttta aagtgagaaa
     5221 aaaatgggaa attttagctt tcttttaaaa aatgacgaat atgaatcttt ttcaaaacct
     5281 tgcattgaag ctgaaaatat gattgctaca tcaactgtgg ctactgcctt tatggcgcgt
     5341 cgtgctttgg agcaggctgt ccattggata tatagtcacg attcatattt agaagctccc
     5401 tattgtgcta ctctatcttc tttagtatgg gatgatgatt ttagggatat cgtagattct
     5461 gaactccaca agcagatagt tctgttgatt cggtggggaa accatgctgc tcatggtggt
     5521 gaaattaagg aacgagaagc gattttagct ttacatcatt tgtatcagtt tgttaatttt
     5581 atcgattatt gttacagcaa tgaatttgtg gagcgttatt ttgatgagaa gtgtttacca
     5641 ctttcagcaa acatcaaata ccgagaaact ccacaatcta tgataaagtt acaagacagt
     5701 ttaccagaac tgcctgattt tcatgaacag atggctgctc agtccgtaga agttcaagag
     5761 atttatactg aaaaacgtga gactgcagcg caacggcaag atgtgccttt ccatattgaa
     5821 caattatctg aggcagagac aagaaagctc tttattgata tcgatctccg tttagcagga
     5881 tggatatttg aagaaaactg tcgtgttgag atagccgttg atggtctcaa gcacggttca
     5941 ggaattggtt actgtgacta tgtactttat ggtaaaaatg ggaaaatttt agcgattgtg
     6001 gaggctaaaa aagcctctgt caatccagaa gtaggggaag tacaggtcaa agaatatgct
     6061 gaagctttgg agaaacatat cggctatcag ccaatttgct ttattacaaa tgggttgaag
     6121 cactatatac ttgatggtcc gaaccgccgc cagattgcag gcttttactc tcaagaagaa
     6181 ttgcaattag tgatggatag acgtcatctt caaaaaccgc ttgaggatat ttctagtaaa
     6241 attagggacg atatttccgg gcgtcactac caaaaacatg ccattgcaag cgtttgtgaa
     6301 gctttctcta atcatcgtag acaggcactt ttggttatgg caactggggc ggggaaaact
     6361 cgtacagcag tttctctagt tgatatctta tcacgtcata actgggtaaa aaacgttctc
     6421 ttcttagccg atagaacttc cttggttaag caagcctatg attcgtttag aaaattactc
     6481 ccagatcttt ccgtttgtaa cttcttagaa gataaagaag gagctcaatc aagtcgtatg
     6541 gtcttttcaa cttatccgac catgattgga gcgattagtg atcaagaaga agtaaatcaa
     6601 cgccctttta ctgttgggca ttttgacctt atcataattg acgaatctca ccgttctatt
     6661 tatcagaaat acaagtccat ttttgattat tttgatgcaa ggattgtagg cttaacagct
     6721 actccgcgtc aagatttaga taaaaacacc tatggattct ttaatttgga gaatggggtt
     6781 ccaacatatg catatgattt ggaagaggct gttaaagacg gatatttagt agcctatcat
     6841 tctatcgaaa ccaaactgaa actacctacg gatggtctac attatgatga tttgtccgaa
     6901 gaagaaaagg aacattttga tagcaaattt gaagacgata gctgtgaaaa agatattgat
     6961 gggagtgtgt ttaattcctt tattttcaat aaaagtacag tagaaattgt tttaaatgaa
     7021 ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac tattattttt
     7081 gctaaaaatc atgaccatgc ggaatatatc agaggtattt ttaacaaccg ctatcctgaa
     7141 aaagggagcg actatgctca ggtgattgat tatagtatta agcattatca gaccttgatt
     7201 gatgatttta aaattaagga gaagtatcct caaattgcga tttctgtcga tatgttagat
     7261 acaggtattg atgtaccaga ggttgttaat ttagtcttct tcaagaaagt acgctctaaa
     7321 actaagtttt ggcagatgat tggtcgagga acccgtctat gtaaagattt atttggacct
     7381 gagcaggata aggaaaactt cttggtattt gattatgggg acaattttga ttattttcgt
     7441 gcagatccaa gagatggaga gggtcgtcac attgtttcgt tgactcagcg tttatttaat
     7501 atcaaagtgg acttgattcg agaacttcag ggacttcaat accaagaaga tcagtttgcg
     7561 agagcatacc gtcagcagct tgtctcggaa cttcaaggtc gtatagagag cttaaatgag
     7621 ttggacttca gggttcgtat ggttttagat acagtttata gctataggaa attggaaagt
     7681 tggcagaatc taactgctgt tacaagtgaa accattcaaa aaaatctctc tccgctttta
     7741 tttgatgaag ataaagaaga tgagatggcc aggagatttg atttgtggtt gcttcatatt
     7801 cagttggggc aactgacagc taaatcttcc actgttcata tttcccaagt gatgaagacg
     7861 gctagagctc tttctgctat tggcaatatc ccgcaggttt ttgagcaggc tgaaattatc
     7921 aggaaagtac aggagcctga attttggaaa gaagttaact tgtctgattt ggaaaaaatt
     7981 cgtcttgcta ttcgagattt attacagttt ttggataaaa cagaccgtaa accctactat
     8041 gttaactttg aagatcgtat actctccact gttcacgaga ccacagcatt tttgcaggtc
     8101 aacgatcttc ggtcttacaa tgaaaaagtt gagcattatt tgaaaactca tctggatgag
     8161 gagtccattt ctaagctata ccataataaa aagttgacat ctgatgatat gcttgcactt
     8221 gaaaaattgc tctgggaaaa attaggtagt aaagcagact accaaagtca ttatgaaaat
     8281 aaggcaattc cgagattggt tcgtgagatt attggcttag atagagagtc tgccaatcgt
     8341 attttttcta aatttttgtc ggatgagaat cttaatgcca ggcagatttc atttgtaaaa
     8401 ttgattgtag actacattgt agaaaatggt tttttagaga cgaaagtgtt aacgcaagag
     8461 ccgtttaaat cttatggttc tgttcaacta ctcttccaac accaactacc agtacttcgt
     8521 aatattgttc aaatcattga acttatcaat aatcgagctg gagaagcggc ttaaattcta
     8581 aagtgattgc catgctgaga ctcatttaaa attaaaaaga gtagaaattt atgctatata
     8641 tgagaagttt tattaggaag aatgtcatcg ttttcctaga atacagtatc agttgttaag
     8701 tggttgataa atttcaaagt agatacttgt accacgatgt ttgttgatcg agttattaac
     8761 aaaagagcta ctttgatttt aaagaaatag aaaacaaaaa gctgagcaag aattcaattg
     8821 caggagaaaa tgaaataata ctcaatgaaa atcaaagagc aaactaggaa actagctgca
     8881 ggctgctcaa aacac
//
LOCUS       DBEJZJ010000055         8418 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000055 DBEJZJ010000000
VERSION     DBEJZJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.55"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(629..937)
                     /locus_tag="ACL3R8_001875"
     CDS             complement(629..937)
                     /locus_tag="ACL3R8_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR1314693.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(934..1242)
                     /locus_tag="ACL3R8_001876"
     CDS             complement(934..1242)
                     /locus_tag="ACL3R8_001876"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR1314694.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1247..2542)
                     /locus_tag="ACL3R8_001877"
     CDS             complement(1247..2542)
                     /locus_tag="ACL3R8_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR1314695.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2560..3969)
                     /locus_tag="ACL3R8_001878"
     CDS             complement(2560..3969)
                     /locus_tag="ACL3R8_001878"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR1314696.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4127..4855
                     /locus_tag="ACL3R8_001879"
     CDS             4127..4855
                     /locus_tag="ACL3R8_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR1314697.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5314..5493
                     /locus_tag="ACL3R8_001880"
     CDS             5314..5493
                     /locus_tag="ACL3R8_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR1314698.1"
                     /translation="MKGKEYENRTVSFAISSKGENISYRVDHRILFDNISFDTSSSGV
                     TLITGKNGTGKSTLL"
     gene            complement(5615..5781)
                     /locus_tag="ACL3R8_001881"
                     /pseudo
     CDS             complement(5615..5781)
                     /locus_tag="ACL3R8_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5859..7169)
                     /locus_tag="ACL3R8_001882"
     CDS             complement(5859..7169)
                     /locus_tag="ACL3R8_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR1314699.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWSTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7406..8278
                     /gene="nadC"
                     /locus_tag="ACL3R8_001883"
     CDS             7406..8278
                     /gene="nadC"
                     /locus_tag="ACL3R8_001883"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR1314700.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2621 a         1476 c         1593 g         2728 t
ORIGIN      
        1 ctgatagagt tgttcacatc ttatttcaat tcactatagt ttaatttaag agtagtattt
       61 actaaggccc aattaaaatc aaagagcaaa ctagaaaacg agtgccattc agctcaaaac
      121 actgatttga gattgcagat aagactagcc ccctcattaa cagatttacg ataaaacgat
      181 gacaaggtgt gttgcttttt gatttctaaa gagtataatg atagatcttt ataaaataag
      241 tgcgaaggaa atgagctttt atagtccttt cgttttaaaa tactatctca gatattctta
      301 tatcgacaag aagtttttga gtcattccct catcatacat attaaataaa tagtggctca
      361 ttcaattttt cactagaata ataagctagt atagtaaact gaaataagat ataaacaaat
      421 aaattggagc ttaacatcca tttccagcaa ttttttagaa actacagtgg actattctag
      481 attcaacata ttataaaaac tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga
      541 tccaatcctt tcaatcattt tgtccaactt ttggaggttc ctacaatgta gtcgtcatta
      601 ataaagacag atgggaatga cagtgttcct atttattttg atagagatcg atgaattctt
      661 tagatagcaa ctgaataatc tctgttgaag ccatttggtc ttctgcatgc ataaatagca
      721 aggagaatcc tattttttct ccagtagctt ctttttgtat gagattagag tgaatcttgt
      781 gcgcttctac taaggagtct tccgcttctt caactttaat tttcgcttct tttaaatttc
      841 ctgccttagc tagttggatg gcttcaataa aggatgattt ggctgctcca ctattggcaa
      901 tgagctgaaa acagatatat tccatttctt ctgtcatctt atttctccta tccatgcaag
      961 tgcttgttcc agaacttttg ctccattcat cattccgtaa tcccgcatat caatggtatc
     1021 tacagggata tttcctgcaa tttctttcac agcaagtaac tcataacgaa tttgtggccc
     1081 aattagaatg acatctgctt catggatatt ctttttagct tctgtcattg attttgcttg
     1141 gatagagatt tcaatcccac gttcagtcgc actttgttgc atttttttaa caagcatact
     1201 tgtcgacatt cccgcattac atactaataa aatttgtttc ataatcttaa ccttccattt
     1261 cttgttcaac aactttgtca ttaactttga taaatggaat gtatagaaga actccaagtg
     1321 caaagatgat gaattgaact agaactgctc tcacgtcccc tgctgttgct aaccatgcat
     1381 ttaagaatac tggtgtagtc caaggaactt gtataaatgc aggactcatg aatcctgtaa
     1441 ctgttgctaa gtagctgatt aaaataccaa ggactggaac tgtgataaat ggaatagcta
     1501 atgaaatgtt ataaacgatt gggtaaccga ataatactgg ttcattgata ttgaagatac
     1561 caggtccaaa agataattta gccacgtttt tagagacagc attgcgactc actaagaatg
     1621 ttgctattaa taaacataat gtagatccac taccacccat taaagcgaat gtttgtattt
     1681 gtgataggtt gatgatgtgt ggaatggctt gtccattatt tgctgcagtg atgttttcag
     1741 taatgttaat taatagtaat ggttctagga tggcactgta aataactgct tggtgaatac
     1801 caaatagcca taacatattt cctaaagagt aaataataat gaccccgatt aagcttgtac
     1861 caatatgacg aattggttct tgaataaaga ttgtaatgat tgagattaag ttcattccag
     1921 ttatattgaa taataatgct gaaacaaccc caaataagga gatgacggtc atgactggaa
     1981 gtaatacgct aaatgatcta ctaacagctg gtggaatatt ttcaccaagg ttcatttgta
     2041 aagctttaac gtttgataat tcaatgaata attctgttgc aataatcgct acgataaccc
     2101 cggcgaacat tgcgcctgta cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg
     2161 catcttttgc tccgtcagga actacagaaa ctgtatttgg catcatcaca attaaagaaa
     2221 ctaatgatag cattgatgct gctaacgggt tttcgaaatc tctgttttta gctaagaaat
     2281 aaccaaccat tacagcaata atcatacctg aaatacttaa agtaccgttt gcaattgtta
     2341 ttccccaata ttggaatctt gttaatgtat ccccttggaa aatccactta aataccgtgt
     2401 tgttcaaaag aacgattaaa cctgccaaaa tatataatgg cattactgtt acgaatgcat
     2461 ctcttagggt ttttaaatga atttggttcc ctagtttacc agcaaaggtg gcaaattggt
     2521 ctataaattt tgagtttttc atatgaatat ctcctctctt tactcctcaa tttctacttc
     2581 aaaaccgtta ttgtcactta ctttgcgata ccatcttcct gagctcttga tggttctctt
     2641 ttgcgtttct aaatcaacgg agataaatcc gtaacgattc ttatatgcat tattccaaga
     2701 ccagcaatca aatgcggtcc aagcgtggta tccaaaacag tgacttccct cttcaatggc
     2761 tttatgtagc catcttaaat gttcttcata aaattcaata cgatacacgt catcgataac
     2821 tccattttca tcgataaacc gtgcttcgtt ttcaacaccc attccgtttt cactgataaa
     2881 ccatgggata ttaccatatt cttccttcac aatcatagca atatcataaa tggctttcgg
     2941 aaaaatttcc caaccacgat atggattcat gcgacgctcc agccattcat actctttgaa
     3001 gtattggtct ggcatccagg gcgtctgata ttcctcagga tttgcttgtg cttgaacacg
     3061 ttttggatgg tagtagttta ctccaagaaa atcaaccgta tttgatttca tcagttgaag
     3121 ctctttttcg gtatgactcc ataacacgcc atctctctct agctgtttta ccaatctttc
     3181 tgggaaagtt cctttaacag ctggattcaa gaagactttg ttaaagaagt catctgtaaa
     3241 tcgacttgct tctaagtctt ctggagaatt acttcttgga taagcaggtg tcaagtttaa
     3301 aataatccca atctttccat caagttctaa tgagcgatat agttgaatca cttttgcact
     3361 agcaaggttt agattataga tgacttgtac ggcctctttt ccctttcctt ttagatttgg
     3421 ataatggaaa gcatataagt atcctgcttc tggaatgacc attggctcat tgaaagttgt
     3481 ccagtaatga accttatctc caaagcatgt gaaagcagtc ttggcaaact tcacgaataa
     3541 ctccactaca tgtttgcttt cccaaccacc gtatttttga agaagttcca ctggtaaatc
     3601 aaaatgatgt aaattcatca caagatccat ctggttcttt ttagcttctt caatgatggc
     3661 attgtagaaa gcaatacctt ttggatcagg ctcacctgtc tctaaattct tgatgagtcg
     3721 actccattgg atggaagtgc ggaaagaatt aactccaatt tccttcatca agtggaaatc
     3781 ttcggtgtaa gtatgaaaaa agttactggc tacaagaggt ccgacattat cgaaaaaatc
     3841 ttctggatgc gttttgaacc agtagtccat cacattttca tgtacttttc catattgacc
     3901 ttctgtctga ggtccgctag aagcagctcc ccaccaaaac agattaggaa atactaactt
     3961 ttttttcatg ctcaacctcc tttctattat tctatacata aagtatagca taattttaaa
     4021 atttgtctag acatttttaa aaattgttga tacatatctt gtgtttgcct catttcttga
     4081 actttgttat actactatta gaatattata gagagaacca gattaaatga gtacaaaata
     4141 tttatttatt tacaatgaga ttcgtgaaaa gattctttgt aataaatata ccatgaacga
     4201 acaattgcct gatgaaatga cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa
     4261 aaaagcttta gacttgttag tttctgaggg cttaattttt agaaaacgtg ggcagggaac
     4321 ctttgttctc tctcgtggca gctcaaaaag aaaattaatc gttccagaaa gagatatccg
     4381 gggactgaca aaaatatctg aagatgctca ttctacaatt gactcgagga ttattcactt
     4441 caaattagaa tttgcaaatg aatttttagc agaaaaacta caggtcgctt tgcagagtcc
     4501 agtttataat atttaccgtc tgcgtattat tgacggtaaa ccttatgttc tggaacaaac
     4561 ttatatgagt accgatgtta ttccaggtat tactgaagat attttacaaa aatcgattta
     4621 caattacatt gaaggaaagt taggattgca tattgccagt gctacaaaaa tcttgcgagc
     4681 ttcttctagt tcagaaaatg agcaacatta cttgcagctc cttccaacgg aaccggtatt
     4741 tgaagtagaa caagtggctt atttggataa cggaactccg tttgagtact cgattagtcg
     4801 tcatcgctat gatttatttg aatttaattc ttttgcatta cgacattcct cctaggagaa
     4861 aatgtgaaaa tgaagccaat cttttacaga ctctagttta agaaaaattt aaaacagggc
     4921 aagaaggtcc catctatgct taaatggttt ctcttttcta aataagatgg ctttaaaaga
     4981 gtgatcgttt tatccatcat gttgaaaaat atcttcgtat agcttataga gtaggtactg
     5041 aaattgttca cctgatctac ttcttatagt tatttagttt taaatggtgt ttcaaacatt
     5101 cttacactga cgagaagttt ttgagtcttt tcttgtaaca catatagtat actgaggtta
     5161 gaatagtaga ctgtgacttc taaaaaattg ctagaaatga atttcaatct cccaatttat
     5221 ttgttcatat cttcttttaa tatattaaat aaattctgaa tcataatcat ttaaaaaaat
     5281 tttatttttt atttttcatt acgaataata tagatgaagg ggaaagagta tgaaaacaga
     5341 actgtttctt ttgctattag ttcaaaagga gaaaatattt cgtatagggt ggatcatcgt
     5401 atattgtttg ataatatttc ttttgatact tcgagttcag gcgtgacatt aattactggt
     5461 aaaaatggta caggaaagtc aactttacta tagtagattg aaactagaat agtacacatc
     5521 tacttctaaa atattgttag aaatcgattt gactatcctg atctatttgt cctgttctta
     5581 tttcatttca ctacatctca aattgagtat gacgaagtgc gctcccatgt cctgggaacg
     5641 cactttcttc atatttttca tattcttgaa tccatcgata aagactattg ggatgaattt
     5701 ttaaagttga actaatcatt tttacaggat gaggtttaca gcagagagtt tgaaggcttt
     5761 atcaaaggtt tttcttggca taatgacttt tcctcgtttc cacttaattt tgtgtctact
     5821 ttattatacc aagtccaccc ttaagttaga taataaatct aacttaagga agctagaagg
     5881 atgagaatcc aggtggtcaa gagtcccaaa cttaagctga tggggacacc cagaataatt
     5941 tgctttttga aggcaaggcc acgttcctct atattgggaa gtgagagttg aatgagagaa
     6001 ccagctgatg aaaagggtga gatattagta gatagagcgc caataacggt ggctgttgtg
     6061 agtaagtgaa tatcaatctg aggattttga gcactgatga tagcaatgat gggaaagagg
     6121 gctggagcta caacggatag ggtggaacta aagagtgaca tcactccggc tatcacacaa
     6181 aagaacagag gtaaccagaa atgaggaatg gatgttgtca tgaggtgccc tatcagtgtg
     6241 actaaacctg acttgaccgc tagagacatt agtaagctca tgccgcagag catgataatt
     6301 gtagcccagg gaactttagc caaaatggct tcttgcttcc ctaatttgag ccttaaggcg
     6361 aggcagacca tgagtattga gacaaagcca atatcaaatg ttttttgata agtagctatc
     6421 caggcgatgt ttgggaaaat gagatgcaac aagggaaaaa gccaaaccaa aaccatgctg
     6481 ctgatcatga gcaaggtggt ttgtctttga accttgctga ggagtggtgg ttggtcaata
     6541 gtcaaggatg agtttgttct tcccttacta tagtgactgt aacaggataa taaaagcaag
     6601 acgatgagtg ggtagataat gctgacgata aagatatgat tgccaagtga aaaagcttgc
     6661 tcttcccatc ccatttgctt aaacaggcct tgaaagacaa tgcctgagct actggttatc
     6721 aaattagccc ctcctgaagc tccccaattg acggcttgag ctccaatcaa agggtgtttg
     6781 tccgcttttt gacagagggt aatcgctaga ggacagcaaa cggccatagt agtgaaaaat
     6841 ccagcaccta aagcagacaa aagggttgcc atcaggtata aaatcatgta gagggcgtta
     6901 gggtaggtgc gtgtgcggta gagaatgtgt tgagccaaaa catcaagagt accgttagtt
     6961 attgcaaagt tataaaagag agagacgcta aaaatggtaa aaaagagtga ggttgaccaa
     7021 aaatgaagaa gttctttggg gcttaatccc atgagagtgg ttgcgatgag gtaagaaaaa
     7081 gcaatagcca gcaggccaat attgattttg gtgcggtaac caattccaat ggctagagca
     7141 atggcgctaa tcattattaa atgaatcatt gaattgtcct ttcagttaga atatggaaat
     7201 aggttggcaa ttttggcgct caaaagacca cctgtttcct attggtactt gactattata
     7261 cacaaaaaaa atacaattgt cttgacaatt gtattgacaa ttgttagaat taaaaatgag
     7321 gtattcaggc ttgtgatttc ctatggaagt taatagtgat tgcctctaat gcttacaagt
     7381 gatattaaaa atagaggacc tagtgatgtc aatcatttca actgatttaa ccccttttca
     7441 aatagatgat acattgaaag cagccttgcg agaagatgtt cattccgaag attacagtac
     7501 caatgccatt tttgatcatc atggccaagc caaggtgtcg ctttttgcca aggaagctgg
     7561 tgttttagcg gggctaaccg tttttcaaag ggtttttacc ctatttgatg ccgaggtgac
     7621 cttccagaat cctcatcaat ttaaggatgg ggatcgtttg actagtggcg atttggtttt
     7681 agaaatcata ggctcggtga gaagtctctt aacatgtgaa cgcgttgcct tgaatttttt
     7741 acaacattta tcagggattg cttcgatgac agctgcttat gtagaagcct taggcgatga
     7801 ttgcattaag gtatttgata ctcgaaaaac tactcctaat ttacgtcttt ttgagaaata
     7861 tgccgtgaga gttggcggtg gctataatca tcgctttaat ttatcagatg ctatcctgct
     7921 aaaagacaat cacattgcgg cagtaggtag tgttcaaaag gcaattgctc aagcgcgtgc
     7981 ctatgcccct tttgtgaaaa tggtcgaggt ggaagtggaa agccttgctg ctgccgaaga
     8041 agctgcggcg gcgggtgctg atattatcat gttggataat atgtcattgg aacagattga
     8101 acaggccatt accctaattg caggacgttc tcggattgaa tgttctggaa atattgatat
     8161 gaccactatt agccgttttc gtggtttagc gattgattac gtctccagtg gtagtttaac
     8221 ccatagtgct aagagtcttg atttttccat gaaggggtta acctaccttg atgtctaagt
     8281 tgtaaaataa actaactttt taaaggatgt ctttcctcta gaacgagttt tatgtcagat
     8341 agtttaaacg cctcttcaaa tatagtaaaa tgaaccaaaa atagtacaca atgtggtata
     8401 atctttttat ggcatatt
//
LOCUS       DBEJZJ010000056         7652 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000056 DBEJZJ010000000
VERSION     DBEJZJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.56"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..741)
                     /gene="phtB"
                     /locus_tag="ACL3R8_001884"
     CDS             complement(<1..741)
                     /gene="phtB"
                     /locus_tag="ACL3R8_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGR1314701.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNAN"
     gene            complement(899..3349)
                     /gene="phtA"
                     /locus_tag="ACL3R8_001885"
     CDS             complement(899..3349)
                     /gene="phtA"
                     /locus_tag="ACL3R8_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGR1314702.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3602..5335)
                     /gene="ptsP"
                     /locus_tag="ACL3R8_001886"
     CDS             complement(3602..5335)
                     /gene="ptsP"
                     /locus_tag="ACL3R8_001886"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR1314703.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5341..5604)
                     /locus_tag="ACL3R8_001887"
     CDS             complement(5341..5604)
                     /locus_tag="ACL3R8_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR1314704.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5955..6173
                     /gene="nrdH"
                     /locus_tag="ACL3R8_001888"
     CDS             5955..6173
                     /gene="nrdH"
                     /locus_tag="ACL3R8_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR1314705.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            6254..>7652
                     /gene="nrdE"
                     /locus_tag="ACL3R8_001889"
     CDS             6254..>7652
                     /gene="nrdE"
                     /locus_tag="ACL3R8_001889"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR1314706.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAM"
BASE COUNT         2117 a         1606 c         1416 g         2513 t
ORIGIN      
        1 atttgcatta taactagaac ttgaagaagg acgagatccc tgcttcccat tccaataggc
       61 ttctgcagca gctaactcgc tagctgataa ctcattctta ggaatgtaat ggtaatggtc
      121 gccgtgagga acgatataag catcacccgt gtcctcaatg atatcagatg cattgaagat
      181 atacccatca tccgttgtat aacgtccttg ggctctggct gcagcaacag cattatctgc
      241 tcttgagtta tgattatgac tgcgttcctg cttctgacgt ttaatctctt cttttgtccg
      301 aatattatcc gcatgagctg catccttaag gtaaacatag tatttaccgt ttaccttaag
      361 gacataacca cccttgattt cattgacaat gtctgaatcc ttcaactgat aattcggatc
      421 tttcatgagg agctcttcac tgatgatggc atcataagga accttgccat tatagtaatg
      481 ataatggtct ccatgagagg tcacataacc ttgatccgta atcttgataa caatttgttc
      541 ggcgttgatc ccctccctct tactgacttc atctggtgtc aagttttctg ccttttgacc
      601 agcctgatca ccatctatat aagcaactcg attagactct ttcttatcct gaccagcttg
      661 gtaacgtcca agctcatagg aacaaacact tagggcaagg actgccactg aacctgctag
      721 atatttttta ttgattttca ttctttcctc ttttcttaag tatatttgat tcactataaa
      781 gtaataaacc ggttaattaa ctagttaata gtttactctt tttaatattg cttgtcaaga
      841 attttacata tatacataat aaaaatgaaa gcctctttat cgagactttc atttttcatt
      901 agtttatttt ttccttactt acagatgaag gattacttcc ttttaacaac gcaagtaatt
      961 tttctgcttc tgccatgata ctattgttat ccataatttg aagagtcaaa ttatttcgta
     1021 aaccagctag agtttctgtt gcattggctt tcagactaga atccgttact ttcgcaagca
     1081 aaacttctgc ttctttgagt tgggcttcta ctttttcagt ctctacttga gggacttctg
     1141 gctcagcagg tgtttcctct actggctctt catccgcttt gaagttctta tttggatctt
     1201 cactgtggtc tttcttgcct aacacatgct cactggcatt gccccatcca tcattagaat
     1261 gtggacgttc gtcagggtgt tctacgtagt acttaatcgt cgcaaacaaa tcttccaagg
     1321 tatagccatt tggagctttg tatgtgtgat catcaaacca agcaaattta atgttatggt
     1381 aatgatcctt atgaggaata atcaaattac cgtttttaac ctcaactgta tgctcaacca
     1441 tatatggaag tcgaacgagt ggaattcgtt tttccccttt cacacgattg taaatagctg
     1501 ctgcactatc tccagttgga tttgctttaa catctgcgtc tggagatgga ggtaggatac
     1561 ctttttcttt agtataggct tgagctgcaa ctttttcctt atcagaaagg ctgtcttttc
     1621 caatccagtg actatggccc atatgaggcg ttacatatgc atctccttca tcactgatta
     1681 tatcatgttc atcaaaaata taaccatctg acgttgtata cttatcagct aattgagcaa
     1741 tacgaacttc gtcttcagta tactcaattt gagaatttgg cttgccaagt cgctctggat
     1801 gggtaattgg tgctaggaat gccaataaat catctaccaa tttttcttta ttagtcgatt
     1861 catcattcaa gcgttctaat aatttgtcta aggcttggaa atcagaatta cgacccttat
     1921 tttcaaacaa ggctttatga gcctcagtta acagattata tgctttatca taaaattctt
     1981 ggtcacgagg agcaacattt tcttttttag cagttaaagt gtgtgaaaca ctctcttgtt
     2041 ttgataactt gctttcaaga tttttaacag tttcagatgg taaatctttc gcaaagacat
     2101 aacgagagat gcccttttct tcgaatacat atccttcccc aacttttcgt accagctgac
     2161 taaccaaaga agaatttgag tctattttaa gatttggtgc aggttgcggg cctggactag
     2221 gttccggagt cggttgtgga cttggttgtt ctggccttga atctggtacc caatggtttg
     2281 aacgataacg aaggggaata atacgagcga ttcgttcttc caattcagac atttgagagt
     2341 aagggatgaa gtggtaatga tctccgtgtg gcactgcaac acctctagct gttcgacttg
     2401 tgatttgcgc tgggtcgaaa acaaggccat cagattctac atgtcgttga ctcaaaggca
     2461 gtttgtagag ctgtttcaag agactatcaa tgtcattact ttgacttgtt tgactgttag
     2521 tgttgctgtt gttgcttgtg ttagtatttg tagttcctgg attgcttaca gaaggtaccc
     2581 agtttgttct tgaagtgtta tcgctatttt gtcggcgata ggttcttgaa tttgacagat
     2641 ttccccgacc agataggaag gcttctgcag cagccaactc gctagctgat aactcattct
     2701 taggaatgta atggtaatga tctccatgag gaacgatata agcatcacca gtatcctcta
     2761 tgatatcaga agcattaaag atataaccat catctgtagt atagcgtcct tgcgaacgtg
     2821 ccaaggcaac agcaccatcg tttcttggag tcccaccttc acgatgttga ctatgttctt
     2881 gtttttgtcg attgatttcc tcttttgtac ggacgttatc cgcgtgggca gcatccttaa
     2941 ggtaaacata gtattttcca tctaccttga taacatatcc acccttgacc tcattaacaa
     3001 tatcctcatc ttttagctta tagttcggat ctttcatgag taattcttca ctgaaaatcg
     3061 catcataagg aaccttacca ttgtaataat gatagtggtc gccatgtgaa gtgacatagc
     3121 cttggtctgt tatcttgatg acgatttgct cagcattgat tccttcacgc ttgctaacct
     3181 catcaggagt caaattctcc gttttttgcg tcgcttgttt tccatctata taggaaacac
     3241 gattattttc cttaaccgtt ctagcttgat acagtcccaa ctcgtaagaa caaacactta
     3301 aaatcaaagc tgccgcagaa ccaacaaggt atttcttatt aattttcatc gaaactctct
     3361 ttctatttga tatttctagt tgcaattcat ttctaaattg cagaaactcc tctctattac
     3421 ttaactggtt aatagtttac tcctaaatct ccaacttgtc aagaatttta tgaaccattt
     3481 aagtattttt tgttctgact actacttttt caagaaaatc tttctataag aaagattttc
     3541 ttgaaaattc tttttaaaat atcaaaaaaa tccctgtaac tgagttgcag ggacttttcg
     3601 attaatcaaa attaacgtat tctttttgaa gttcaagaac ttcttccatt gttgagcatt
     3661 ctgtaagggc acggtttgcg tactcttcca tcttagctgt gtcgagtttc ttcatcaagc
     3721 tgcgtgtacg aagtacagat gttgctgaca tagagaactc atccaagccc attccgacaa
     3781 gaagtggaac agcttgttgg tcaccagcca tctcaccaca cataccagcc catttacctt
     3841 cagcgtgagc tgctttgatc acattgttaa tcaagcgtag gattgatggg ttgtatggtt
     3901 ggtaaaggta tgaaacttgt tcgttcatac ggtctgctgc cattgtatat tggatcaagt
     3961 cgtttgtacc aattgagaag aagtcaactt ctttagcaaa ttggtctgca agcatagccg
     4021 ctgcaggaat ctcgatcatg ataccaactt ggatgttatc cgcaactgca acaccttcag
     4081 caagaaggtt tgctttttct tcatcaaaga ctgctttcgc tgcacggaat tctttcaaga
     4141 gcgcaaccat tgggaacatg atacgcaatt gaccgtgaac agacgcacga agaagagcac
     4201 ggatttgtgt gcggaacata gcatctccag tctcagagat agagatacga agagcacgga
     4261 atccaaggaa tgggttcatt tcgtgaggca tatcgaagta aggaagttcc ttatctccac
     4321 cgatatccat tgtacgaacg acaacaggtt taccgttcat tccttcaaga acagccttgt
     4381 atgcttcata ctgctcatct tcagttggga agtcttgaga atccatgtac aagaactctg
     4441 tacggtaaag tccaacagct tctgcaccgt tgttgttaac accttcaacg tcttttggag
     4501 taccgatatt agcagccaac tcgaagtgtt taccgtcagc agtcactgtt tgagcatctt
     4561 tcaagagcgc ccattcagct ttttgtttcg cataagcttc accagctgct ttaaattctg
     4621 ccgcttgttc atcagttggg ttgataataa cctcaccagt gatcccgtta acagcaagga
     4681 tgtcaccgtc tttaacgatt tcagtgatgt tgtttgtacc taatacagct gcaatttcaa
     4741 gtgtacgtgc catgatagct gagtggcttg tacgtccacc gatgttggtt acaaaagctt
     4801 ttacaaagtt tttgtccaat tgagctgtat cagatggtgt caagtcatgt gcaatcacaa
     4861 tcacttcttc attgatagaa gctgggtttg gcaatttttt accaagaagg tttgccaata
     4921 cacgttttgt cacatcgcgg atatccgctg cgcgttcttg catgtatggg ttgtcttcca
     4981 tgccttcaaa gatagtgata aacatatctg taacttcttt cagacctgct tctgcattca
     5041 ctttcttcgc acggatagtt tccttgattt ggctgatcat ttctgggtca gcaagaacca
     5101 ttaagtgagc atcaaaaact tgagctgctt cttcaccgag cgtacctact gctttctcgc
     5161 gaataacaga aagctcgtct tgtgatgcct gtagagcggc atcaaggcga gcttcttctg
     5221 cgtttgtatc ttcgactgta atagtctcaa atgacaaatc cggctgaacg agtagatatg
     5281 cttttgcaac tgcaacaccg tcagatgctg cgattccttt aagcatttct gtcatttccc
     5341 ttatgccaat ccttcttttt ccattgtttc tgagattgca gcgatagcgt catctgcatc
     5401 tgcaccttca gctgagatag ttacgtcagc accttggcca acaccaagac tcataacacc
     5461 cataattgat ttaaggttaa ctgatttacc tttgtactca agagtgatat ctgaagcaaa
     5521 tttgctagca gtttgtacca acaatgttgc tggacgtgcg tgaatacctg tttctgccac
     5581 tacgtggaaa tctttagaag ccatagtttg actctccttt tgttctttct ttttttgagt
     5641 tatatgtgat aacccttaca atttagtatt ataccatctt ctaggatttt tttcaagcat
     5701 tttctggatt ttccttcaat ttcctttcag ataacttgct gaaaatcttc tatcctagat
     5761 aacaaaacac aggatatagt ttctttaaaa acaatttata ggataatcat tgctatttca
     5821 caatacaaac actatatatt gtgtttatat ataaaaacaa caaaagaaca ccactatatt
     5881 tagttcaaat cattgacaaa attttatttt ctgatatact aagatagtat taaattttga
     5941 agaggagtta cacaatggta accgtttatt ctaaaaacaa ttgtgtccaa tgtaaaatga
     6001 ccaagcgttt cttggacagt aataatgtct cttatcgtga aatcaatctt gatgagcaac
     6061 ctgagtacgt cgatcaagtt aaagagctcg gttttagcgc agctcctgtt atccaaacac
     6121 caactgaagt cttttcaggt ttccaaccag gaaaactgaa acaattagca taatcttagt
     6181 acatcatcca gaagaaactg cttttagggc taacttagaa gcctttcttt tgtaattaga
     6241 taagggaaat tttatgggat taaaacatct tgaagacgtg acttacttcc gtcttaataa
     6301 cgaaattaac cgtcctgtta atggacaaat catgcttcat aaagataagg aagccttgga
     6361 tgctttcttt aaagaaaatg tagttccaaa cactatggtt tttgattcaa tcaaagacaa
     6421 aatcaattac ctcattgaac acaactacat cgaaacagcc tttatcaaga aataccgtcc
     6481 agagttcttg gaagaattgg ctcaatttat caaagaccaa aacttccaat tcaagtcatt
     6541 catggcagct tataaatttt acaatcaata tgccttaaag actaatgacg gtgaatacta
     6601 tcttgaaaat atggaagacc gtgtcttctt caacgccctt tatttcgctg atgggaatga
     6661 agctgttgca atcgatattg ccaatgaaat catccaccaa cgctaccaac ctgctactcc
     6721 ttccttcttg aatgctggac gtgctcgtcg tggggagttg gtatcttgtt tcctaatcca
     6781 agtgacggat gatatgaact ctatcggacg ttctatcaac tcagctcttc aactttcacg
     6841 tattggtggt ggtgtgggaa ttaccctcag caaccttcgt gaagctggtg cacctatcaa
     6901 aggctatgaa ggagctgctt caggtgtcgt tcctgttatg aagctttttg aagacagctt
     6961 ctcttactcc aaccaattgg ggcaacgtca aggtgctggt gttgtctacc tcaacgtctt
     7021 tcacccagat atcatcgctt tcctttcaac taagaaagaa aacgctgatg aaaaagtacg
     7081 tgtcaagact ctatcacttg gtgttgtagt acctgataaa ttctacgaat tggctcgtaa
     7141 aaatgaagaa atgtacctct tcagccctta ctctgtagaa aaagaatacg gtgtgccatt
     7201 caattacatc gacattactg aaaaatacga tgaattggtc gcaaatccaa atattcgcaa
     7261 gacaaaaatc aaggcgcggg atttggaaac tgaaatctct aaattgcaac aagagtctgg
     7321 ctatccttat gtagtcaaca tcgatacggc taaccgtgca aatcctgttg atggaaagat
     7381 tatcatgagt aacttgtgtt ctgagattct tcaagttcaa gaaccaagct tgatcaacga
     7441 tgctcaagaa ttccttcaaa tgggaacaga tgtttcatgt aatctgggtt caaccaacgt
     7501 ggttaacatg atgacttcac ctgattttgg tcgttctatc cgtgctatgg ttcgtgccct
     7561 tactttcgtt acagatagtt cacatatcgt agctgtacca acgattgacc atggaaatag
     7621 ccaagcccac acctttggtc tcggtgccat gg
//
LOCUS       DBEJZJ010000057         7466 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000057 DBEJZJ010000000
VERSION     DBEJZJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.57"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            129..284
                     /locus_tag="ACL3R8_001890"
                     /pseudo
     CDS             129..284
                     /locus_tag="ACL3R8_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            484..3759
                     /gene="rexB"
                     /locus_tag="ACL3R8_001891"
     CDS             484..3759
                     /gene="rexB"
                     /locus_tag="ACL3R8_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR1314707.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3756..7406
                     /gene="addA"
                     /locus_tag="ACL3R8_001892"
     CDS             3756..7406
                     /gene="addA"
                     /locus_tag="ACL3R8_001892"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR1314708.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2277 a         1569 c         1585 g         2035 t
ORIGIN      
        1 actatattag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
       61 gaaatatttt agcatccacg atgtactatt atagtttcaa tttactatag ttcaatcatt
      121 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
      181 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
      241 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagtcttgtt
      301 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
      361 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
      421 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
      481 gagatgaaat tactttatac tgatattcga acttctttga cagaaattct aacaagagag
      541 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
      601 tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttctattacc
      661 gtcacgcgct ttgctcaaat ggctcgttat ctggtcctga atgatttacc agttaaaact
      721 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
      781 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
      841 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
      901 gatgaggata agaggacgga tttactcttg atttttgaga aagtaacagc ctatcttaat
      961 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
     1021 aaggtaagta gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct
     1081 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
     1141 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
     1201 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
     1261 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
     1321 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
     1381 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagcattcg tcagaaatta
     1441 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
     1501 taccagttat ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga
     1561 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
     1621 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
     1681 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
     1741 ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
     1801 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
     1861 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
     1921 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
     1981 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
     2041 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
     2101 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
     2161 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
     2221 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
     2281 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
     2341 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
     2401 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
     2461 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
     2521 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
     2581 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat
     2641 ccagctatcc caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
     2701 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
     2761 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
     2821 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct
     2881 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
     2941 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
     3001 gatgttgcac ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
     3061 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
     3121 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
     3181 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
     3241 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
     3301 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
     3361 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa
     3421 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
     3481 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
     3541 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
     3601 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
     3661 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
     3721 gcttggtttg aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg
     3781 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
     3841 ctgccgaaca aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg
     3901 ctggttctgg aaagaccttt gtcatggtag agcgcattct ggaccaattg gcgcgtggtg
     3961 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
     4021 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
     4081 aacacttggg tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
     4141 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
     4201 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
     4261 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
     4321 ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc
     4381 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
     4441 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
     4501 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
     4561 atttagaaaa tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata
     4621 gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
     4681 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
     4741 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata gcgattctcg
     4801 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
     4861 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
     4921 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
     4981 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggatatcaac catattcaag
     5041 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
     5101 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
     5161 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
     5221 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
     5281 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
     5341 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
     5401 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
     5461 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
     5521 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
     5581 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacacc cttcgtgtca
     5641 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
     5701 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
     5761 atctctatga gaaactagtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
     5821 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
     5881 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
     5941 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
     6001 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
     6061 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
     6121 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
     6181 ttatcctcaa tatggatcaa gatttcaaca aacaagactc tatgtcagaa gtcattctca
     6241 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
     6301 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
     6361 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
     6421 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaatccaagg
     6481 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
     6541 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
     6601 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
     6661 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
     6721 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
     6781 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
     6841 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
     6901 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
     6961 tgcagagaat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
     7021 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
     7081 ttgacacagc actcggtcag gaaatttttg ctaataccga ccatctctat cgcgagcaac
     7141 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
     7201 ttgatggcta tctgctttac gaaaacaaaa ttgttttgtt cgactacaag acagaccgct
     7261 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
     7321 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
     7381 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
     7441 agcttcgcct tgctgtatat atggtt
//
LOCUS       DBEJZJ010000058         6993 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000058 DBEJZJ010000000
VERSION     DBEJZJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.58"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(296..1987)
                     /gene="argS"
                     /locus_tag="ACL3R8_001893"
     CDS             complement(296..1987)
                     /gene="argS"
                     /locus_tag="ACL3R8_001893"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR1314709.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2123..2569
                     /gene="argR"
                     /locus_tag="ACL3R8_001894"
     CDS             2123..2569
                     /gene="argR"
                     /locus_tag="ACL3R8_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR1314710.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2620..5154
                     /gene="mutS"
                     /locus_tag="ACL3R8_001895"
     CDS             2620..5154
                     /gene="mutS"
                     /locus_tag="ACL3R8_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR1314711.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5301..>6993
                     /locus_tag="ACL3R8_001896"
     CDS             5301..>6993
                     /locus_tag="ACL3R8_001896"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314712.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1902 a         1368 c         1649 g         2074 t
ORIGIN      
        1 tttggttagg tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc
       61 tctaaatcga ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa
      121 gcggctagcg tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt
      181 aggacataaa tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga
      241 ataggatttg gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca
      301 tcttctctgg cgcttctact ccaagcaagc gaagggcttc tttgagaacg actgcggttg
      361 cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg
      421 catagtattt gttaaaggat tgagccaggc taattgcaaa tttagcaatg atagaaggtt
      481 caaagttatc tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt
      541 cccagctttc agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt
      601 tgcgtaagat agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct
      661 cgaaggatac catagcttct aggtcgaagt cgtatccatt tgtacggtca gttttgaggt
      721 catagaattt aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt
      781 caggattttt agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct
      841 ctagcaagat gacattccct ttacgagtag agagcttctt cccttctttt gtaaccagac
      901 caaaaggaac gtgggtaatg tcgtcactcc aatcgtagcc catctcttgc aagacagctt
      961 tgagttgttt aaagtgggca gattgctctt gaccaacgac gtagatagat ttagcaaatt
     1021 ggtattcatt tttacggtag agggctgcag ccaagtcacg tgtgatatag agagttgcac
     1081 catcagactt cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt
     1141 gggcaccttc tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca
     1201 tcttatcatt gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt
     1261 aaaggcggtt aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt
     1321 cctcatctcc attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt
     1381 cattttcagc ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag
     1441 cttttacagc ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt
     1501 taccccagtc tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat
     1561 gtgacaagct atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga
     1621 tattcggact agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat
     1681 agtgttcttt ttcagtggta acagcttgca atacttgagc agaaatggca gatttatcaa
     1741 ggaaaaagtt aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt
     1801 tttcagccag ttcagccgca atcatttgtg gtgctttacg ttcgactttt gcaagagaaa
     1861 aagcagggaa agcaatgtct cccatttctg agtttttagg ggtttccagt aactttaaaa
     1921 tagcctcttg gtccaggcta tcaatgatgc tagataattc gctagcaatc aattcttttg
     1981 tattcattaa gagctccttt ttggactttt ctactatttt atcacaattt taaagaaaga
     2041 agaaaaaatt tttgaaatct cctgtttttt tggtataata tggttataaa tatagttata
     2101 aatatgcacg caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat
     2161 gattactgag gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa
     2221 tgtttgtgtg acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt
     2281 caagaaaaat gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt
     2341 ggaatttttg tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca
     2401 taccaaattg ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggatgaatg
     2461 gattttagga acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt
     2521 tgccaaactc atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag
     2581 ttgctctcaa gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca
     2641 cccggcatgc aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt
     2701 cggatgggtg atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg
     2761 gaaatttcct taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt
     2821 ccctatcatt ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct
     2881 atcgcagagc agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt
     2941 caggtcatta cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt
     3001 ttggtttcca tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg
     3061 ggtgactttt atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac
     3121 ctcaaggctc gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc
     3181 agccgccaga tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta
     3241 ttggatttgc gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt
     3301 catcggactc agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag
     3361 gatttcttgc agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc
     3421 tcaggtaaga aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg
     3481 atgcgtctct tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa
     3541 cgtcaagaag tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac
     3601 agtctcaagg gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc
     3661 aatccaaagg atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg
     3721 attttagaag ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc
     3781 cctgagttgg agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca
     3841 gatgggggaa ttatccgaac tggatttgat gagactttag acaagtatcg ttgcgttctc
     3901 agagaaggga ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc
     3961 agcacgctca agattgacta caataaaaag gatggctact attttcatgt gaccaattcg
     4021 caactaggaa atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc
     4081 tttggaaccg aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca
     4141 gccaacctcg aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag
     4201 cgtttacaag ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt
     4261 gtggctgaaa cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc
     4321 cggaaagggc gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat
     4381 acgattcaga tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg
     4441 aagtctacct atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat
     4501 gttcctgctg aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca
     4561 gcagatgact tggtttcggg tcagtcaacc tttatggtgg agatgatgga ggccaataat
     4621 gccatttcgc atgcgaccaa gaactctctc attctctttg atgaattggg acgtggaact
     4681 gcaacttatg acggaatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc
     4741 ggagctaaga ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta
     4801 caacacttgg tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt
     4861 cacaagattg aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct
     4921 ggcttgccag cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa
     4981 ggaacagaga gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc
     5041 tttgataggg cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat
     5101 atgacaccta tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa
     5161 gactcactag ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg
     5221 ctagaataac atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt
     5281 ctatttttta aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggcct
     5341 tggcttcgct cctgatgaca ggcttgatgg ttgctagttc acttctgcaa ccgcgttatc
     5401 tgcaggaagt attagacgcc ctccttactg ggaaatatga agctatttat agtatcgggg
     5461 cttggttgat tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg
     5521 cagcctatat tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc
     5581 aaaccttttc ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga
     5641 caaatgatat caaccagatt cagaacgttg tcatgatgac cttccaaatt cttttcagac
     5701 ttcccctctt gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt
     5761 gggtgattgt tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga
     5821 tggggcctcg ttttgctaaa tttcaaaccc ttcttgagcg catcaatgcc attgccaagg
     5881 aaaatttacg tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta
     5941 agtttacaga ggtctcaaac gagcttcttg gtcaaaacct ttacattggt tatgcctttt
     6001 cagtagtgga accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc
     6061 tggtcgcggg aatgattcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta
     6121 attacctaag ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca
     6181 gccgtgccat gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga
     6241 ccttcaagga tatcccagat gaagagttgg ttggaagtct tagctttgaa aatgtgacct
     6301 ttacctatcc aatggacaag gaaccgatgc tgaaaaatgt gagctttact attgaacctg
     6361 gtcaaatggt tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga
     6421 ttccacgtct ctttgatcca caggacgggg ccattaaaat tggtggcaag gatattcgag
     6481 aagtgagtga aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt
     6541 ttagtggaac gattgcagat aacttgagac aggggaaggg aaatgctacc ctatttgaaa
     6601 tggagcgcgc agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct
     6661 ttgaaagtcc agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt
     6721 cgattgcgcg tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag
     6781 ccttggatgc caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga
     6841 cgacaaccat tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg
     6901 ttctaaatca aggacgattg attggtcaag gtacgcatgc agacttggtt gccaacaatg
     6961 ccgtttaccg tgaaatctat gaaacacaga aat
//
LOCUS       DBEJZJ010000059         6692 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000059 DBEJZJ010000000
VERSION     DBEJZJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.59"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(8..271)
                     /locus_tag="ACL3R8_001897"
                     /pseudo
     CDS             complement(8..271)
                     /locus_tag="ACL3R8_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            465..2231
                     /gene="patB"
                     /locus_tag="ACL3R8_001898"
     CDS             465..2231
                     /gene="patB"
                     /locus_tag="ACL3R8_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR1314713.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2370..3059
                     /locus_tag="ACL3R8_001899"
     CDS             2370..3059
                     /locus_tag="ACL3R8_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR1314714.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3063..3242
                     /locus_tag="ACL3R8_001900"
     CDS             3063..3242
                     /locus_tag="ACL3R8_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314715.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3229..4578
                     /locus_tag="ACL3R8_001901"
     CDS             3229..4578
                     /locus_tag="ACL3R8_001901"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR1314716.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4702..6162
                     /gene="gltX"
                     /locus_tag="ACL3R8_001902"
     CDS             4702..6162
                     /gene="gltX"
                     /locus_tag="ACL3R8_001902"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR1314717.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6176..6610
                     /locus_tag="ACL3R8_001903"
     CDS             6176..6610
                     /locus_tag="ACL3R8_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR1314718.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT         2101 a         1285 c         1436 g         1870 t
ORIGIN      
        1 tgagtaccta ccgcagatga ggggaacccc gtttgaccat tctttctgct aaatcaatct
       61 gacctgactg ataaatagaa gaatccagtc cagcgaaagc ttgtaattga gcaggattat
      121 caaaggcatg aatatttcga atctcggcta aaatgaccgc ccctaaacga ttctcaatcc
      181 cagtaaccgt cgtgatgacc gagttgaact cagccatcaa gtcattgaca catttttccg
      241 ccttgtcact gagcctcttg taatgtttga tgttttcatt acacgagata aaacgtctat
      301 gcgttatcaa actcattacc aattaaaaca aatgtggtta gatcctttcg gaaattgtca
      361 agcgattgga ggaaatgaac taatccacag cggcttattc caagtatacc acttgggctt
      421 tggcagtagc taactgcgct aaatataata taaggaggag taaaatgaag acagttcaat
      481 ttttttggca ttattttaag gtctacaagt tctcatttgt agttgtcatc ctgatgattg
      541 ttctggcgac ttttgcccaa gccctctttc cagtcttttc tggacaagcg gtgacgcagc
      601 tagccaattt agttcaagct tatcaaaatg gcaatccaga acttgtatgg caaagcctat
      661 caggaatcat ggtcaatctt ggcctgctgg ttttggttct atttatctct agtgtaatat
      721 acatgtgtct catgacgcgc gtgattgcag aatcgaccaa cgagatgcgc aaaggtctct
      781 ttggtaagct tgctcagttg acggtttctt tctttgaccg tcgacaagat ggcgatatcc
      841 tgtctcattt taccagtgat ttggataata tcctccaagc ctttaacgaa agcttgattc
      901 aggtcatgag caatattgtt ttatacattg gtctgattct tgtcatgttt tcgagaaatg
      961 tgacgctggc tctcatcact attgccagca ccccattggc tttccttatg ctgattttca
     1021 tcgtgaaaat ggcacgtaaa tacaccaacc tccagcagaa agaggtaggg aagctcaacg
     1081 cctatatgga tgagagcatc tcaggccaaa aagccgtgat tgtgcaagga attcaagagg
     1141 atatgatggc aggatttctt gaacaaaatg agcgcgtgcg caaggcaacc tttaaaggaa
     1201 gaatgttctc aggaattctt ttccctgtca tgaatgggat gagcctgatt aatacagcca
     1261 tcgtcatctt tgctggttcg gctgtacttt tgaatgataa gtctattgaa acaagtacag
     1321 ccctaggttt gattgttatg tttgcacaat tttcacagca gtactaccag cctattatcc
     1381 aagttgcagc gagttgggga agccttcagt tggcctttac tggagctgaa cgaattcagg
     1441 aaatgtttga tgcagaggag gaaatccgac ctgaaaaggc tccaaccttc actaagttgc
     1501 aagaaagtgt tgaaatcagt catatcgatt tttcatactt gcctgataaa cctattttga
     1561 aagatgtcag catttctgcc cctaaaggcc agatgacagc agttgttggg ccgacaggtt
     1621 caggaaaaac gactattatg aacctcatca atcgctttta tgatgttgat gctggtggta
     1681 tttattttga tggtaaagac attcgtggct atgacttaga tagtcttaga agcaaggtgg
     1741 gaattgtatt gcaagattcg gtcttgttta gcggaacgat tcgagacaat atccgatttg
     1801 gtgtgccaga tgctagtcag gaaatggttg aggtagcagc aaaagcaacc cacattcacg
     1861 actatatcga aagtttgcct gataagtacg atactcttat tgatgatgac cagagcatct
     1921 tttcaacagg gcagaagcaa ttgatttcaa tcgctcgaac cctgatgaca gatccagaag
     1981 ttctcattct cgatgaagca acttcaaacg tagatacggt gacagaaagc aagattcagc
     2041 atgccatgga ggtggttgta gcaggtagaa ctagtttcgt cattgcccac cgcttgaaaa
     2101 ccattctcaa tgcagatcag attattgtcc ttaaagatgg agaagtcatt gaacgtggta
     2161 accaccatga acttttgaag ctaggtggtt tttattcaga actctatcac aatcaatttg
     2221 ttttcgaata agaaagaagt tgtcctatgt gggcagcttt ttcttgtcca taaaaaatgt
     2281 ttatcacagc cttaaaaaaa acatattaga cgaaagtcat tttgagtgat atgataggac
     2341 tatcgttagc attcgaaagg agaggcatca tggctagaac ggttgtagga gttgctgcaa
     2401 atctatgtcc cgtagacgca gaaggcaaaa tcattcattc atctgtatct tgtagattcg
     2461 cagagatcat tcgtcaagtc ggtggtctcc ctttagtcat tcctgttggt gatgagtcag
     2521 ttgtacgtga ttatgtggaa atgattgaca aactcatttt gacaggaggc caaaatgttc
     2581 atcctcagtt ttatggagag aaaaagaccg tcgagagcga tgattacaat ctggtccgtg
     2641 acgaatttga attggcactc ttgaaggaag cgcttcgtca gaataaacca attatggcaa
     2701 tctgtcgcgg tgtccaactt gtcaatgttg cctttggtgg aaccctcaat caagaaatcg
     2761 aaggtcactg gcaaggacta cctttcggga catctcactc tattgagaca gtagaaggaa
     2821 gcgtggtggc taagctattt gggaaagaaa gtcaggtcaa ctcagtccat cgtcaaagca
     2881 ttaaacattt ggcacctaat ttccgtgtaa ctgctattga ttcaagagac caaactattg
     2941 aagcgattga gtctatcgac gagcaccgca ttatcggttt acagtggcat ccagagtttc
     3001 tggttaatga agaagatggc aatttagaat tatttgagta tttattgaat gaactgtaac
     3061 gattggaaca tctggtcgtt ctttttttta ttttttcaaa atttttagaa tgtggtattt
     3121 tacgcaaacg tttgaattct gataaaaatt ggagaaattc gacaaaaaaa cttgaaaaaa
     3181 acgaaggtaa gcgttatgat agaaaagaag aaatattgga ggaagaacat gtcacatatt
     3241 aaatttgatt attcaaaagt tttagacaaa tttgttgcac cacatgaagt ggaatacatg
     3301 caatcacaag taacagcagc agatgaattg atccgtaaag gaactggtgc tggtagcgac
     3361 ttcttgggat ggttggacct tcctgaaaaa tacgatcgcg aagaatttga ccgcatcttg
     3421 aaagctgctg agaaaatcaa gtcagacagc gatgttttgg ttgtgatcgg tattggtgga
     3481 tcttaccttg gtgcaaaagc agcaatcgac ttcttgaatc accattttgc taacttgcaa
     3541 acaaaagaag aacgcaaagc tccacaaatc ctttacgcag gaaactcaat ctcatctact
     3601 taccttgctg acttggtaga gtatgttgca gacaaggact tctcagtaaa cgtaatttct
     3661 aaatcaggta caacaactga accagcgatt gctttccgtg tctttaaaga actcttggtt
     3721 aagaaatacg gtcaagaaga agctaacaag cgtatctatg caacaactga ccgccaaaag
     3781 ggtgctgtta aggttgaagc agacgctaac ggttggggaa catttgttgt tccagatgat
     3841 atcggtggac gcttctcagt attgacagcc gttggtttgc ttccaatcgc agcatcagga
     3901 gctgacatca aagctcttat ggaaggtgcg aatgcagctc gcaaagacta cacttcagac
     3961 aaaatctctg aaaacgaagc ttaccaatac gcagccgttc gtaacatcct ttatcgtaaa
     4021 ggctatgcaa ctgagatctt ggtaaactat gagccatcac ttcaatactt ctcagaatgg
     4081 tggaaacaat tggctggtga atcagaagga aaagaccaaa aaggtatcta cccaacttca
     4141 gccaacttct caactgactt gcactcactt ggtcaattta tccaagaagg aactcgtatc
     4201 atgtttgaaa cagttgtccg tgttgacaaa cctcgtaaaa acgtgcttat tcctactttg
     4261 gaagaagacc ttgacggact tggttacctt caaggaaaag acgttgactt tgtaaacaaa
     4321 aaagcaactg acggtgttct tcttgcccac acagatggtg atgtaccaaa catgtatgtg
     4381 actcttccag agcaagacgc tttcactctt ggttacacta tatacttctt cgaattggca
     4441 attgcccttt caggttactt gaatgctatc aacccatttg accaaccagg tgttgaagct
     4501 tataaacgta acatgtttgc ccttcttgga aaaccaggat ttgaagaatt gagcaaagaa
     4561 cttaacgcac gtctataata gaagaaaaga gtggtttgcc cactcttttt actctcttta
     4621 tccatagaaa ttggactcag ccaagacttg tgatataata tagaaagcaa aaaggcagac
     4681 gcctagataa taggagaaac tatgtcaaaa gatatccgcg tacgttacgc accaagtcca
     4741 acaggactac tacacatcgg aaatgctcgt acagcattgt ttaattactt gtatgcgcgc
     4801 catcatggtg gaacatttct catccgtatc gaagatactg accgtaaacg ccatgtcgag
     4861 gatggtgaac gttcacaact tgaaaacctt cgctggttag gcatggattg ggatgaaagt
     4921 ccagaatcac atgagaatta tcgccagtct gagcgtttgg acttgtatca aaaatacatc
     4981 gaccaactat tagctgaagg aaaagcctac aaatcttacg ttacagaaga agagttggca
     5041 gctgaacgtg aacgtcaaga agtagctggc gaaacaccac gctacatcaa tgaatacctt
     5101 ggtatgagtg aagaagaaaa agcagcttac atcgcagaac gtgaagcagc agggaccatc
     5161 ccaactgttc gtttggctgt caatgagtca ggtatctaca agtggcatga tatggtcaaa
     5221 ggcgatatcg aatttgaagg tggcaatatc ggtggtgact gggttatcca aaagaaagac
     5281 ggttacccaa cttacaactt tgccgttgtt atcgatgacc acgatatgca aatctctcat
     5341 gttatccgtg gagatgacca tattgctaat acaccaaaac agcttatggt ctatgaagct
     5401 cttggttggg aagctccaga gttcggtcac atgaccttga ttatcaactc tgagactggt
     5461 aagaagttat ctaaacgtga tactaataca cttcaattta tcgaagatta ccgaaagaaa
     5521 ggttaccttc cagaagcagt ctttaatttt attgctcttc ttggttggaa cccaggtggt
     5581 gaagatgaga ttttctctcg tgaagaactc attaaacttt ttgatgaaaa ccgcctcagc
     5641 aagtcaccag cagcctttga tcagaaaaaa ctagactgga tgagcaatga ttatatcaag
     5701 aatgcagacc ttgaaaccat ctttgaaatg gcaaaaccat tcttagagga agcaggccgt
     5761 ttgactgaca aggctgaaaa attagttgag ctctataaac cacaaatgaa atcagtagat
     5821 gagattatcc cattgacaga tcttttcttc tcagatttcc cagaattgac agaagcagag
     5881 cgcgaagtca tgacgggtga aacagttcca acagttcttg aagcattcaa agcaaaactt
     5941 gaagcgatga cagatgataa atttgtgaca gaaaatatct tcccacaaat taaagcagtt
     6001 caaaaagaaa caggtattaa agggaaaaat cttttcatgc ctattcgtat cgcagtttca
     6061 ggcgaaatgc atgggccaga attaccagat acaattttct tgcttggacg tgaaaaatca
     6121 attcagcata tcgaaaacat gctaaaagaa atctctaaat aaagaggata caataatgga
     6181 catctgggaa aagatgtacg aagaagcaca gaaactatac aatccacatg aagtatcaga
     6241 ctttgtttat gccaatcatg ttgtagctgc agtagaagca gaagatggac aaatatttac
     6301 aggattctgt atggagggaa cctgtggtgt tttccatctc tgcgcagaac gggcggccct
     6361 cttcaatatg taccaatttt caggacaaac taaggttaag aaagtattag cctttcgaga
     6421 taaaccacct tatggtggaa gttcagccat gccttgcggt gcttgtagag aattcctttt
     6481 agagcttaat gctgaaaata aagatgcaga attcatgatg gactataata taagaaaaac
     6541 agttaaagtc gcagaactaa tcccttattg gtggggagaa gaacgtgctt ctaagtttaa
     6601 tgagcaatag aagagtcagt ataattctgg ctctttttac tataagtttc aaaaaaaatg
     6661 aaaaaaatta gaaaaagtag ttgacaaagt tt
//
LOCUS       DBEJZJ010000060         6662 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000060 DBEJZJ010000000
VERSION     DBEJZJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.60"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..230
                     /locus_tag="ACL3R8_001904"
     CDS             <1..230
                     /locus_tag="ACL3R8_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR1314719.1"
                     /translation="TTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIE
                     KTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            291..1253
                     /locus_tag="ACL3R8_001905"
     CDS             291..1253
                     /locus_tag="ACL3R8_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1314720.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1430..2437
                     /gene="gap"
                     /locus_tag="ACL3R8_001906"
     CDS             1430..2437
                     /gene="gap"
                     /locus_tag="ACL3R8_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR1314721.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2505..3380)
                     /locus_tag="ACL3R8_001907"
     CDS             complement(2505..3380)
                     /locus_tag="ACL3R8_001907"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR1314722.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3467..5662
                     /gene="pbp2a"
                     /locus_tag="ACL3R8_001908"
     CDS             3467..5662
                     /gene="pbp2a"
                     /locus_tag="ACL3R8_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR1314723.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5715..5867
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001909"
     CDS             5715..5867
                     /gene="rpmG"
                     /locus_tag="ACL3R8_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR1314724.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5877..6053
                     /gene="secE"
                     /locus_tag="ACL3R8_001910"
     CDS             5877..6053
                     /gene="secE"
                     /locus_tag="ACL3R8_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR1314725.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6108..6644
                     /gene="nusG"
                     /locus_tag="ACL3R8_001911"
     CDS             6108..6644
                     /gene="nusG"
                     /locus_tag="ACL3R8_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR1314726.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2073 a         1168 c         1439 g         1982 t
ORIGIN      
        1 taaccacacc atcggttatt attatggata atgcaagatt ccatagaatg ggtaagctag
       61 aactcttgtg tgaagagttt gggcataaac ttttacctct tcctccctac tcacctgagt
      121 acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag gtattaccaa
      181 gttgcaatac cttttacgag gcttttttat cctgctcttg tttcaattga ctatagttca
      241 cggatacagt tgggaaagaa gctattaaat atttggagag tccttttggg atgaacatgt
      301 caaatattac tatagatggg caagaaatgg atctgagtca aacgatgcct tcttatgctc
      361 aagtagtgag tctttatgat gatacaagta tctctgttag taataatgag acggacaaag
      421 tgttggctgg atccctctat actgatacaa atgaacaggg attaacgatt ccaagcagtt
      481 tactaaaaaa ttggaatgaa cagacaggaa aaaatttgac agctaatgat cttattggca
      541 aatcagtctc agccagcatt gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc
      601 aaacgaagat tgtacgtgta atcaatgatg aagatgacat ggaggacagc aacagtttca
      661 tgctgtctca tcaaatggaa acgattttga aagaggctgg atttacgaaa gctgtatctt
      721 attttatctt ggaactcaaa gatccatcac agacaaaagt agtaacagaa gaattacaga
      781 aaaataagaa gtatactgtg ctttctcaac agagagttct tgatattgtg attaccttta
      841 ttcgtgttat tcagggatta ttgattgtgc tttcatcaca agctattgtg gtagcagcgg
      901 ttatgattgg tatcattatt tacatcaata tcatgcaacg ttccaaggaa ataggtgtca
      961 tgaaagcagt tggttatcag aatcgtgatg tcaaaggaat ttttatttac gaggctatct
     1021 ggattgtagg catcgccttg ctgctggcat ttttggttgc acaaggggtg ggaagtttgg
     1081 cgaatgcgat tgtaagtcac ttttacccat ccatcactaa ggtttttgaa ttaaatcttt
     1141 tatctgtttt aggaactcta gttttcgctc tattacttgg ttatgtctca gcctacttcc
     1201 cggcgcgtaa gattagtaaa atggatccta tagaatcgtt atgctatgaa tagtaaggga
     1261 ttccttggtt tacagtctta aaaagaaact aacatagaaa aacaatggcc atacttgcaa
     1321 ttcaactcaa atagttgtat aataggtttg ttgaaaggtg atttgtagtg attcaagtta
     1381 ctcttttcac aataaaaatt tcatgatttt cataaggagg aaatcactaa tggtagttaa
     1441 agttggtatt aacggtttcg gacgtatcgg tcgtcttgct ttccgtcgta tccaaaacgt
     1501 agaaggtgtt gaagttacac gcatcaacga ccttacagat ccagttatgc ttgcacactt
     1561 gttgaaatac gacacaactc aaggtcgttt cgacggtact gttgaagtta aagaaggtgg
     1621 atttgaagtt aacggtaaat tcatcaaagt ttctgctgaa cgtgatccag aacaaatcga
     1681 ctgggctact gacggtgtag aaatcgttct tgaagctact ggtttctttg ctaagaaaga
     1741 agcagctgaa aaacacctta aaggtggagc taaaaaagtt gttatcactg ctcctggtgg
     1801 aaacgacgtt aaaacagttg tattcaacac taaccacgac gttcttgacg gtactgaaac
     1861 agttatctca ggtgcttcat gtactacaaa ctgcttggct ccaatggcta aagctcttca
     1921 agacaacttt ggtgttgttg aaggattgat gactactatc cacgcttaca ctggtgacca
     1981 aatgatcctt gacggaccac accgtggtgg tgaccttcgc cgtgctcgcg ctggtgctgc
     2041 aaacatcgtt cctaactcaa ctggtgctgc aaaagctatc ggtcttgtaa tcccagaatt
     2101 gaatggtaaa cttgacggat ctgcacaacg cgttccaact ccaactggat cagttactga
     2161 attggtagca gttcttgaaa agaacgttac tgttgatgaa gtgaacgcag ctatgaaagc
     2221 agcttcaaac gaatcatacg gttacacaga agatccaatc gtatcttcag atatcgtagg
     2281 tatgtcttac ggttcattgt ttgacgcaac tcaaactaaa gttcttgacg ttgacggtaa
     2341 acaattggtt aaagttgtat catggtacga caacgaaatg tcatacactg cacaacttgt
     2401 tcgtactctt gaatacttcg caaagattgc taaataattc ttgagttgat agaaagcaag
     2461 gctttgtggt cttgcttttt tatatggaaa aatggatgac acgatcatcc attctttttt
     2521 aattcttttt caaatgtatt tgaaagggta gtgaaagtta gcctctctaa agtaagtggg
     2581 tgggtaaagg aaagtcggaa ggcatgaagc ataagccggc ttgtctttga tttactatta
     2641 tagagagggt ctcccaggat aggaagatta tgatgcaaaa ggtgcacacg aatctgatgg
     2701 gttcgccctg tctttagctt gcaatgagcc aaggaagtct tgtttgagaa ttgctttaat
     2761 ctgcttacat gcgtttcagc atattgccca ttttttgcat caactattct ttttctacga
     2821 tcatggcgat cacgtccaat tttgtctctg aaaacaagtt cttttctgtt gatatttcca
     2881 tcaactagag cccaatattc tctagaaatc tcttttttct ccaataagcg attgagaatg
     2941 ggcaggataa aaggattttt ggcaaagaga actaagccac tggtttccat gtccagacga
     3001 tgaacgacat agcaggtttg gccaacatag gtactgacat ggttaagaag ggcaatttcg
     3061 tttggttgat taccatgcgt tttcatcccc tctggtttgt ttacaataat caagtgttga
     3121 tcttgataaa cttcctgcac taagtctggg ttgccccaag ggatcgtctt ttgggaataa
     3181 tcttcctcgt caaaagtcaa ctggcaaaca tctccaggat ttacgatttc gttccagtgg
     3241 acttcttctt gatttatcaa aatatgtttc ttgattctca aaaaatgacg gatttttcta
     3301 gggatgagga gttgttcctc aagtaattgc tttaccgtca tttgaggtag agaggcgggt
     3361 aatgtaaatg tgaattgcat acagatattg taacaaaaaa agccctattt ggataggaaa
     3421 tagctaaatt cttgtcttcc tatgatgaag atgataaaat aaacgcatga aattagataa
     3481 attatttgag aaatttcttt ctctttttaa aaaagaaaca agtgaactag aggactctga
     3541 ttctactatc ttacgtcgct ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat
     3601 tcgaaaattc tggcgtcgtt atcatctaac aaagattatc cttatactag gtttgagtgc
     3661 aggattgcta gttggaatct atttgtttgc tgtagccaag tcgaccaatg tcaatgattt
     3721 gcaaaatgcc ttgaaaactc ggactcttat ttttgaccgt gaagaaaaag aggctggtgc
     3781 cttgtctggt caaaagggaa cctatgttga gctgactgac atcagtaaaa acttgcagaa
     3841 tgctgttatt gcgacagaag accgttcttt ctataaaaat gacgggatta actatggccg
     3901 tttcttcttg gctattgtca ctgctggacg ttcaggtggt ggctctacca ttacccaaca
     3961 gctggctaaa aacgcctatt tatcgcagga tcaaactgtt gagagaaaag cgaaagaatt
     4021 tttccttgcc ttagaattaa gcaaaaaata tagtaaggag caaattctaa ccatgtacct
     4081 taacaacgct tattttggaa atggtgtgtg gggtgtagaa gatgcgagta agaaatactt
     4141 tggagtttct gcatcagaag tgagtctgga tcaagctgcg actctggcag ggatgctcaa
     4201 ggggccggaa ctgtataatc ccttgaattc cgtagaagat tctactaatc ggcgcgatac
     4261 tgtcttgcag aatatggttg cagcaggata tattgataaa aaccaagaaa ccgaagctgc
     4321 tgaagttgat atgacttcgc aattgcacga taagtatgaa ggaaaaatct cagattaccg
     4381 ttacccctct tattttgatg cggtggttaa tgaagctgtt tccaagtata atctaacaga
     4441 ggaagagatt gtcaataatg gctaccgcat ttacacagag ctggaccaaa actaccaagc
     4501 aaatatgcag attgtttatg aaaacacatc gctatttccg agggcagagg atggaacgtt
     4561 tgctcaatca ggaagtgtag ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg
     4621 tcaagttgct gacaatgata aaactggatt ccggaatttc aactatgcaa cccaatcaaa
     4681 gcgtagtcct ggttctacaa ttaagccttt agttgtttat acgccagcag ttgaagcagg
     4741 ctgggctttg aataagcagt tggataacca taccatgcag tatgacagct ataaggttga
     4801 taactatgca gggatcaaaa cgagtcgaga agttcctatg tatcaagcct tggcagaatc
     4861 gcttaatcta cctgctgttg ccactgttaa tgatttgggt gtcgacaagg cttttgaggc
     4921 aggcgaaaaa ttcggactca acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg
     4981 aagcggtgtt gaaaccaacc ctcttcaaat ggctcaagca tacgctgcct ttgcaaatga
     5041 aggtttaatg cctgaagctc attttattag tagaattgaa aatgctagtg gacaagttat
     5101 tgcgagtcat aaaaattcac aaaaacgggt gattgataag tctgtagctg acaagatgac
     5161 cagtatgatg ttggggactt tcaccaacgg taccggtatt agttcatcgc ctgcagacta
     5221 tattatggca gggaaaactg gaacaactga agcagttttt aatccggagt acacaagtga
     5281 ccaatgggta attggttata ctccggatgt agtgattagc cactggcttg gctttccgac
     5341 cactgatgaa aatcactatc tagctggctc tacttcaaac ggtgcagctc atgtctttag
     5401 aaacattgcc aataccattt taccttatac gccaggaagt acctttacgg ttgaaaatgc
     5461 ttataagcaa aatggaattg caccagccaa tacaaaaaga caagtacaaa ccaatgataa
     5521 tagccagaca gatgataatt tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga
     5581 ggctagccgg gctatctcag atgcgaagat taaggaaaag gctcaaacaa tatgggattc
     5641 gatagtcaat ctatttcgct aagatgcttg tcaaagccta gctttcttgt tataatggat
     5701 aagatggagg cgttatggca ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga
     5761 gaaactattc aatcaagatc agcggaaacc ccaagcctac acgactagaa gtaaataaat
     5821 tttgtaagca ttgtggcaag tacactacac acagagaaac gagataggag agagcgatgc
     5881 gttttattgg agatattttt agacttctta aagacacaac atggccaact cgcaaggaaa
     5941 gctggagaga ttttcgttct atcatggaat acacagcttt ctttgtagta attatttaca
     6001 tttttgacca gttgattgtt tcaggtttga ttcgatttat taacattttt tagaagatta
     6061 gtggagttaa ttacactaga aatcttctat ttatgaaagg aaatatcatg gatagttttg
     6121 ataaaggatg gtttgtttta caaacttatt ctggttatga aaataaggtg aaagaaaatc
     6181 tattacaacg tgcacaaacc tacaatatgt tggataatat tttacgcgtt gaaattccaa
     6241 cacaaacagt gcaagttgaa aaaaatggaa agagaaaaga agtagaagaa aatcgctttc
     6301 caggttatgt tcttgtagaa atggtcatga cagatgaagc ttggtttgtt gttcgaaaca
     6361 caccaaatgt tacaggattt gtcggatcac acgggaacag atcaaaacca actccattat
     6421 tggaacaaga aattcgtgac attttggtat ctatgggaca aactgttcaa gaatttgatt
     6481 tcgatgttga gattggtcaa actgtacgta ttattgatgg tgcttttgca gactacactg
     6541 gtaagattac agaaattgat aataacaaag tgaaaatgat tatctctatg tttggtaatg
     6601 acacagttgc agaagtaaac ctaaaccaaa tcgcagaatt ataaccctga gagaggctgg
     6661 ag
//
LOCUS       DBEJZJ010000061         6660 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000061 DBEJZJ010000000
VERSION     DBEJZJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.61"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(148..1158)
                     /gene="ccpA"
                     /locus_tag="ACL3R8_001912"
     CDS             complement(148..1158)
                     /gene="ccpA"
                     /locus_tag="ACL3R8_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR1314727.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1583..2182)
                     /locus_tag="ACL3R8_001913"
     CDS             complement(1583..2182)
                     /locus_tag="ACL3R8_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR1314728.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDITILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2184..3281)
                     /locus_tag="ACL3R8_001914"
     CDS             complement(2184..3281)
                     /locus_tag="ACL3R8_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR1314729.1"
                     /translation="MLERLKSIHYMFCASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTVFVAGNYIWFLFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     ERVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(3281..4018)
                     /locus_tag="ACL3R8_001915"
     CDS             complement(3281..4018)
                     /locus_tag="ACL3R8_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314730.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGIYQETP
                     GGPANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEIPLGSWVGAAILLILGSVAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(4020..4904)
                     /locus_tag="ACL3R8_001916"
     CDS             complement(4020..4904)
                     /locus_tag="ACL3R8_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314731.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(4891..5085)
                     /locus_tag="ACL3R8_001917"
     CDS             complement(4891..5085)
                     /locus_tag="ACL3R8_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314732.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(5082..5288)
                     /locus_tag="ACL3R8_001918"
     CDS             complement(5082..5288)
                     /locus_tag="ACL3R8_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314733.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
     gene            complement(5877..5950)
                     /locus_tag="ACL3R8_001919"
     tRNA            complement(5877..5950)
                     /locus_tag="ACL3R8_001919"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5914..5916),aa:Pro,seq:tgg)
     gene            complement(5966..6039)
                     /locus_tag="ACL3R8_001920"
     tRNA            complement(5966..6039)
                     /locus_tag="ACL3R8_001920"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6003..6005),aa:Arg,seq:acg)
     gene            complement(6049..6134)
                     /locus_tag="ACL3R8_001921"
     tRNA            complement(6049..6134)
                     /locus_tag="ACL3R8_001921"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6098..6100),aa:Leu,seq:taa)
     gene            complement(6142..6213)
                     /locus_tag="ACL3R8_001922"
     tRNA            complement(6142..6213)
                     /locus_tag="ACL3R8_001922"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6179..6181),aa:Gly,seq:gcc)
     gene            complement(6236..6308)
                     /locus_tag="ACL3R8_001923"
     tRNA            complement(6236..6308)
                     /locus_tag="ACL3R8_001923"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6273..6275),aa:Thr,seq:tgt)
     gene            complement(6327..6408)
                     /locus_tag="ACL3R8_001924"
     tRNA            complement(6327..6408)
                     /locus_tag="ACL3R8_001924"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6372..6374),aa:Leu,seq:tag)
     gene            complement(6414..6486)
                     /locus_tag="ACL3R8_001925"
     tRNA            complement(6414..6486)
                     /locus_tag="ACL3R8_001925"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6451..6453),aa:Lys,seq:ttt)
     gene            complement(6511..6583)
                     /locus_tag="ACL3R8_001926"
     tRNA            complement(6511..6583)
                     /locus_tag="ACL3R8_001926"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6548..6550),aa:Asp,seq:gtc)
     gene            complement(6586..6658)
                     /locus_tag="ACL3R8_001927"
     tRNA            complement(6586..6658)
                     /locus_tag="ACL3R8_001927"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6623..6625),aa:Val,seq:tac)
BASE COUNT         2071 a         1530 c         1135 g         1924 t
ORIGIN      
        1 gacttcgtca gttctatctg caacctcaaa acagtgtgtt gcacagcctt taaccagccg
       61 cctagtccgc tctatggtat tcattaagtc aacatctctt gtttaagagc acaaaatcag
      121 gaaatcttct cgattccctg attttttcta tttacgtttt cgtgttgagc tacgttctgt
      181 caaaccatga ggtaagagaa cttcacgttc ttccaactct tccttatgca taatcttggt
      241 caacatacgc atactaatgg caccaaggtc ataaagaggt tgggcaatcg ttgtcaagtt
      301 tggacgggta aagcgtgaga tttgtgaatc atcactagta ataatttcaa aatcttctgg
      361 cacagaaaca cccttatcag ccaaaccgtt caagactcct gctgccaact catcacctgt
      421 cacaactgct gcagttgcat ttgatgaaat caaacgctct gctaaggcgt aaccatcatc
      481 atagctatat ttagattcaa ataccaaacc ctcactataa gcgattcctg cttttttcaa
      541 ggtttccttg tagccaacta aacgaacctt accattgatg tcatccacta gcggaccgct
      601 aacgaaagca atacgctcat tttctttagc aaggtaactc actgcatcaa ttgttgcttg
      661 cttatagtca atattgacac ttggcaactg gtgctcaaca tcgacagttc ctgcgagaac
      721 aatcggagta cgtgaacgcg aaaattctga gcgaatttta tctgtcaagt gataacccat
      781 atagataatg ccatctacct gctttgaaaa gagggtattg acaacagaaa cttctttctc
      841 gttatcttca tcgctattag ctaggacaat attgtacttg tacatttctg caatatcatc
      901 aatcccctta gccaaactcg aaaaataacc attggtaata tttggaatca cgacaccgac
      961 agtggttgtc tttttacttg caagaccacg cgcaactgca tttggacgat aatccaaacg
     1021 atcaattacc tctagcactt ttttacgggt attctctttt acatttttat tgccattgac
     1081 cacacggctg accgtcgcca tggaaacacc tgcttcacga gcgacatcat aaatggttac
     1141 tgtatcatct gcattcattc cttttcctgt cctttctatc tcacacattc ttttacaagt
     1201 agaggtactg attgaagctc tatatctact tacaaaagtg aagatgtgaa aatttcgttt
     1261 tcatatttct acttattcca ttctatcact aattgtaaac actttcaagt gttttttgaa
     1321 gattgattga aaaaatttca tagaaaacct aggtttagct ccttgctacc accttagact
     1381 aaacaaaaag gaggaaacta agccctccta aagttatagt aaaatgaaat aagaacagga
     1441 taaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
     1501 ttctagtttc catctactat aggtattgtt ccattcacta ccgtcaattt tagcacatag
     1561 tcttcatgaa aatattatat catcataacc aaccagattc ttttgcgata ttagctgcct
     1621 ctgttcgatt accagcatcc agttttgaaa gaatattggt gacatagttt cgaatagttc
     1681 cgtttgagag gtaaagctga tctgcgattt cttggttgga taagccccgg gcgattccct
     1741 ttaagacagc aatctcttgt tctgtcaacg gattgggacg ggtcatcacc acttccatca
     1801 attcaggcga atactccttg cgtccttcga ggacggtgtg caaggtttgc atgaggtctg
     1861 caatgcttcg ttcctttaat acataagcat ccactccagc cttgaccgca cgttcaaaat
     1921 acccagcacg cttgaaggtc gtcaccacaa ccacctttgt ttcaagcctt tctgatcgta
     1981 tccactccaa gacttcaaga cctgtcttaa caggcatttc tacgtcaagg atggtgatat
     2041 ctacagactc cttttctaat agttggattg cttcttgccc atttttggct tgaaggacag
     2101 actccacatc tggttgaagc gtgagcaatt gacacatggc atctcgcaac atactttgat
     2161 cttctgcgac taatactttc atcttagttt ctctccttat aaggtagtcg aacttgcact
     2221 tccgttggat gtttctgact gattacactt acttctcctg aaaatggaaa aacacgttct
     2281 cggactgtat ggagctcatc tccttttaga aaagcaaagc cgcagccatc atcacttact
     2341 gttaaaatga gttccttctc tgtccgttct aattttaagt aagctttaga cgctttggca
     2401 tgtttgatga tattggtcac caactcaagc aaaatcatag aagccattga ctccaattct
     2461 tgagtaaggc tagcagtatc tagttggtta tctgtttcca cctcaattcc agcaatttct
     2521 aacatctttt tcacagtctc tagttcggat gtcaaagttc tagacttaag attttccaca
     2581 atggttcgaa cttcacgcat tgattctttg ctaatttgct gtatttctct taattccttt
     2641 tccacttgtg gataagcctg catttgaaat agctgcaagg ctagatctgt cttgacacta
     2701 agcatagcaa aggtatgtcc cagactatca tgcaaatcct gaccgatacg attgcgctca
     2761 ttttctgcta gcaatagatt tatctgggta ttttgcttga cctgagcttc tttcaaatcc
     2821 tcgacaaggc gaattcgaac cgagcccaaa gtcatcaaat cgacaaaagt aagaattaca
     2881 agcatataga ctagaaactc aacttcgatt ctctgaaaaa tcaaaagtcg ccccacaaca
     2941 aggacttgag caaggagaaa tgtccataca tgtaaagact ttaaactacg tacgccaaaa
     3001 tgataaatta agagattgga aaggaaaaat aaaaaccaga tataattccc agcaacaaag
     3061 acggtattcc cagctacata gaccagcatg atcccccaga aaagccaaga taggcgctgg
     3121 ttcttagtta ttaaaacacc caaatacgtc actacaaata gaatatcaac caataaatgc
     3181 caagcaggaa gctccccaat cactacaggt aggatgggaa aaagcataaa aatcaaactg
     3241 gcacaaaaca tatagtgtat gcttttcagt ctttcaagca ttaagcattc tccttatgac
     3301 cttgaaggta aatagtcaaa ccaaataaaa ctgctgaaaa aacaagtaaa taaactgtgg
     3361 ctgatagatt gatgccaccc tcgtttaaga aggtcttgag caactccatc aactgataag
     3421 ttgggagaca cttaccgatc gcttgcatcc agtctggaaa taaagagata ggcatccaga
     3481 gtccgcctaa aacagccaat cctagataaa gaagattgcc cacaacagac atcagctgac
     3541 tagttggtaa gagagtcaag gtcaagccaa gggctacaaa agctacactt cccaaaataa
     3601 gcaaaatcgc agccccaacc cagcttccta gaggaatctc tacacctctt acaaagtgcc
     3661 caactgagaa aaccaccaag attgaaacca aataatcaac cagcatactt gttatctttg
     3721 atagataata ttctaccata tttacagggc tatgacgtaa tgttttctgc cagttgttga
     3781 ttttatctgt atgtaaaaca gctgggaatg aaaacatagc tgtcgacatc atggaaaagg
     3841 ctgtcatgga gatgaggtaa tcacgcataa aattagctgg tccacctggt gtctcctggt
     3901 agatgccaga aaagaataaa tagaaagccg tcggcattcc tacggataat aaataataga
     3961 cgagttgccg tttggtcaat aaaaattcta tcttatttaa tgctatccat cgtttcatct
     4021 tagtcatctc ctttttgcgt ttcttcaaag attgtatcca gcaaactacg attattaact
     4081 tcgatttctt gcatcctaca tcctgcttgg gctaatagtt cccagaaagc atctgcttct
     4141 cgagtgacta cttgtaaaga atcttgcttt agggtccagt tttcaaccaa atttgactgc
     4201 tctacgactt ccttgtaagc tataggaagg ataaagtgct tttctatttc ctcgctacgc
     4261 atagctagag gcgtcgtatc tcgaatcaac tctcccttat ttaagagcaa aatgcggtct
     4321 gcagtgtgtt ccacttcctc aatataatgg gacgaataga gaatggtgac tccttgcgct
     4381 tttaactcct ggacaatttc ccaaaaacgt tgacgagttg aggtatccat ggacgcagta
     4441 ggctcatcta aaaaaacaat ctttggtcgc ccaattaagg tcaagacgaa agaaaagaga
     4501 cgcttttgac cgcctgataa tttttctgcc aactgttctt tttgttgctt gacaaactgc
     4561 aatagttgat caatttcctg attgctcaaa ggatttggat agatacgttg aaagaaagca
     4621 atcaactctt taacttttaa tttctgaacg attacatttt cttgagggag gtaagcccta
     4681 gtatagtcta acttagaact cgtcactggt aaaccttgaa tagatacttg accgcttgtg
     4741 accagtttat ctccaagcaa acaatctaag agtgttgtct ttccggcacc atttggacca
     4801 attaaggcaa cacattcacc atcgttgatt tcaaaggaga tattccgcaa aatttccttg
     4861 tcttttattt tcttactcaa tttctcaact ttaaccaccg tcatgagact ctcctttcaa
     4921 ccactccatt cccataagga aaacgacgaa aatcataaat ccaaacccca aagcaccacg
     4981 aatgaattgg cgaagcaagg cttgatcaaa ccaatcagta aacatttcca ctaaccatac
     5041 caagagtgac aggccgataa agaaatagat gatccctctc ttcattcctc aaactccttt
     5101 ttcacatctc tgactaattt caaaccttct ctaacaagcc aagacatgat tccaaagcca
     5161 gcaaagacct tccaaggaaa atggtagaaa tcctcatcca atcccgaaaa catgagatag
     5221 gtcataactc ctgctactac taaacttact gcgataatca ttttatttct catctcttct
     5281 tcccccattt catactacaa ttatagtctt ttaaaatcag aggagacaga agcttctgtc
     5341 actagaaaat atgacaaatg tcataaaaaa ttctgttcaa aacaagcaag atacactata
     5401 caataaaaca caatcagaaa aatctaaggc aacttcctca aaagagatat caaacccaat
     5461 tcacaccata atgtaaacta atacttattt aaaatcaaaa agagtaaaaa tttttatcag
     5521 acaaacacat atatagtgta ttgaatctat aacagtaggc cttaaatact aaaatatttc
     5581 tataaattaa tttaactttc ctgatagaac tgttcatatc ttatttcaat tctctatatt
     5641 atacgttgaa ccaaaccctt ctattgcttt cttaaaaatt tataagagtt ataaaatctg
     5701 ttaaatttca atgtgtatac ctaaactacg gtatttattg aaaaaactgg agacaaaaag
     5761 tatacgttgc caaaatgaat tactgaaaat caaaaaagag aggaccaaac tgattccctc
     5821 ttaatgtata taatatctag ttttaaaaat acacactcac atatctctgt aatgaatcgg
     5881 gaagacagga ttcgaacctg cgacaccttg gtcccaaacc aagtactcta ccaagctgag
     5941 ctacttcccg agttaaatag aaaaatgcac cctagaggag tcgaacctct aaccgcctga
     6001 ttcgtagtca ggtactctat ccagttgagc taagggtgct ccatattatg ccgaggaccg
     6061 gaatcgaacc ggtacgatcg ttaccaatcg caggatttta agtcctgtgc gtctgccagt
     6121 tccgccaccc cggcctctct aagcgaacga cgggattcga acccgcgacc cccaccttgg
     6181 caaggtggtg ttctaccact gaactacgtt cgcactgttt tcttctatct aaaaatgccg
     6241 gctacatgac ttgaacacgc gaccctctga ttacaaatca gatgctctac caactgagct
     6301 aagccggctc atttgttata tcttaatgcg ggttaaggga cttgaacccc cacgccgtta
     6361 agcgccagat cctaaatctg gtgcgtctgc caattccgcc aaacccgcat atatgacccg
     6421 tactgggctc gaaccagtga cccattgatt aaaagtcaat tgctctacca actgagctaa
     6481 cgagtctaaa ataacttgcg ttaccttaaa cggtcccgac gggaatcgaa cccgcgatct
     6541 tcgccgtgac agggcgacgt gataaccgct acactacggg acctttggga gttaacggga
     6601 tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc cagctgagct aaactcccta
//
LOCUS       DBEJZJ010000062         5882 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000062 DBEJZJ010000000
VERSION     DBEJZJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.62"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            162..362
                     /locus_tag="ACL3R8_001928"
     CDS             162..362
                     /locus_tag="ACL3R8_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314734.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            387..803
                     /locus_tag="ACL3R8_001929"
     CDS             387..803
                     /locus_tag="ACL3R8_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR1314735.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1034..1741
                     /gene="ccdA2"
                     /locus_tag="ACL3R8_001930"
     CDS             1034..1741
                     /gene="ccdA2"
                     /locus_tag="ACL3R8_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR1314736.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLTLASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1752..2309
                     /gene="sdbB"
                     /locus_tag="ACL3R8_001931"
     CDS             1752..2309
                     /gene="sdbB"
                     /locus_tag="ACL3R8_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR1314737.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2683..4074
                     /locus_tag="ACL3R8_001932"
     CDS             2683..4074
                     /locus_tag="ACL3R8_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR1314738.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4217..5134
                     /gene="adcAII"
                     /locus_tag="ACL3R8_001933"
     CDS             4217..5134
                     /gene="adcAII"
                     /locus_tag="ACL3R8_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR1314739.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5142..>5882
                     /gene="phtD"
                     /locus_tag="ACL3R8_001934"
     CDS             5142..>5882
                     /gene="phtD"
                     /locus_tag="ACL3R8_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR1314740.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNAN"
BASE COUNT         1789 a         1054 c         1255 g         1784 t
ORIGIN      
        1 aaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
       61 gcctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      121 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      181 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      241 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      301 caacccaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      361 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      421 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      481 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      541 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      601 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      661 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      721 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      781 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      841 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      901 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
      961 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1021 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1081 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1141 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1201 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1261 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1321 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1381 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1441 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1501 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1561 tctgggcatg gcccttcctt tcttggtctt gacactagct tcaggtctag tcatgccata
     1621 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1681 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1741 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1801 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1861 aaacgactgt acaacaaatt tctgttggaa aagatgctcc agactttaca ttgcaatcca
     1921 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     1981 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2041 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2101 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2161 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2221 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2281 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2341 agattttggt aacttctaaa actaacttcc agtttcccac aacttagctt ttagtatgag
     2401 aaaaacgcgt gacatcagtg gaaatccgtc ttagactaac ttccactggt tttctttttc
     2461 ttgatatata agggttcaaa agcgaaaaga ctcagaaaaa gtgcacgaca aatagcccta
     2521 aaacagagtc gtcttagagt aacttccagt tttgggagag agatggaagt tactttgaga
     2581 agttacggta gtcagatttt tttagaaaaa cattttataa atattcacat atctcctata
     2641 tttatggtaa aatagaatta tcagtttatt ttggagtcaa agatgaatat atttagaaca
     2701 aagaatgtta gtttagataa aacagagatg cataggcatt tgaagttatg ggatttgatt
     2761 ttgctgggta tcggagccat ggtagggaca ggcgtcttta caatcacagg tactgcagct
     2821 gcaacacttg ctggcccagc cctagtgatt tcaatcgtta tttctgcctt gtgtgtggga
     2881 ttatcagccc tcttttttgc agaatttgcc tcgcgagtac ccgctacagg aggtgcctat
     2941 agttacctct atgctatctt aggagaattc cctgcctggt tggctggttg gttaaccatg
     3001 atggagttca tgacagccat atcaggcgta gcttcgggtt gggcagctta ttttaaaggc
     3061 ttgctctctc aatatgggat agcccttcct caggctttaa atggtacctt taatcctcaa
     3121 gcagggacat ttgttgattt attgcctatt cttgtcttgg tcttggtgac ttcgcttgtt
     3181 ttactaaatg ccaaggcagc cttacgcttt aattcgattc tagttatttt gaaattttcc
     3241 gctttagctc tctttgtttt agtaggaatt tggaatatta agtttgataa ttggagcaat
     3301 tttgctcctt acggctttgg acaaatctat ggagctagta ctggtattat ggctggtgcg
     3361 tccttgatgt tcttcggttt tttgggattt gaatccatct ctatggctgt agatgaagtc
     3421 aagactcctc aaaaaaatat tcctagaggg attgtcttat cgctttctat cgtaaccatt
     3481 ctctatgcct tggtgaccct tgttttgact ggtgtggttc actatagtca tttaaatgtc
     3541 gatgatgccg ttgcctttgc ccttcgtagt gttgggatta gttgggcagc caactatgtg
     3601 tcattagtgg ctatcttgac cttgattaca gtttgtattt cgatgaccta tgccctatcg
     3661 cgtatgattt acagtttagc acgtgacggc ttagtgcctg ctgcctttaa ggaactgacg
     3721 aagactagca aggtaccaaa gaatgctact atcttgacag gtctagcttc agcagtagca
     3781 gcaggaatgt tcccactagc cagtattgca gcctttttaa atatttgtac cttagcctac
     3841 ttgatcatgc tggcttatgg tctgattcgc ttacggaaag aaaaaggaat gcccaaagct
     3901 ggggaattta aaacaccatt ggtacctctg ttaccaattt tatcgatcat catttgttta
     3961 tccttcatgt tacagtataa tatgaatacc tggattgctt tcctagttgc gttgttagta
     4021 ggaagtatta tttacttcac ttatggctat aagcattcta ccatagaaga ataaagtgaa
     4081 agtctattga gttgttgaca ctcagcagat ttttatatgt gaaagaaatt tcaaattttt
     4141 tctaaaaata tcttgacaga ttaaattttc aggagtagaa tatttactag ttaattaaat
     4201 ggttaaggag ttgttcatga agaaacaaaa tttattttta gtcctgttaa gtgtctttct
     4261 tttgtgcttg ggggcttgtg gtcaaaagga aagtcagaca ggaaagggga tgaaaattgt
     4321 gaccagtttt tatcctatct acgctatggt taaggaagta tctggtgact tgaatgatgt
     4381 tcggatgatt cagtcaagta gtggtattca ctcctttgaa ccttcggcaa atgatatcgc
     4441 agccatctat gatgcagatg tctttgttta ccattctcat acactcgaat cttgggcagg
     4501 aagtctggat ccaaatctaa aaaaatccaa agtgaaggtc ttagaggctt ctgagggaat
     4561 gaccttggaa cgtgtccctg gactagagga tgtggaagca ggggatggag ttgatgaaaa
     4621 aacgctctat gaccctcaca catggctaga tcctgaaaaa gctggagaag aagcccaaat
     4681 tatcgctgat aaactttcag aggtggatag tgagcataaa gagacttatc aaaaaaatgc
     4741 gcaagccttt atcaaaaaag ctcaggaatt gactaagaaa ttccaaccaa aatttgaaaa
     4801 agcgactcag aaaacatttg taacacaaca tacagccttt tcttatctag cgaagagatt
     4861 tgggcttaat caacttggta ttgcaggtat ctctcctgaa caagaaccaa gtccacgaca
     4921 actaacagaa attcaggaat ttgttaagac ctataaggtt aaaacgattt ttacagaaag
     4981 taacgcttct tcaaaagtag ctgaaactct tgtcaaatca acaggtgtgg gtcttaaaac
     5041 tctgaatcct ttagagtcag acccacaaaa tgacaagacc tatttagaaa atcttgaaga
     5101 aaatatgagt attctagcag aagaattaaa gtgaggaaag aatgaaaatc aataaaaaat
     5161 atctagcagg ttcagtggca gtccttgccc taagtgtttg ttcctatgaa cttggtcgtc
     5221 accaagctgg tcaggttaag aaagagtcta atcgagtttc ttatatagat ggtgatcagg
     5281 ctggtcaaaa ggcagaaaat ttgacaccag atgaagtcag taagagagag gggatcaacg
     5341 ccgaacaaat tgttatcaag attacggatc aaggttatgt gacctctcat ggagaccatt
     5401 atcattacta taatggcaag gttccttatg atgccatcat cagtgaagaa cttctcatga
     5461 aagatccgaa ttatcagttg aaggattcag acattgtcaa tgaaatcaag ggtggctatg
     5521 tgattaaggt agacggaaaa tactatgttt accttaaaga tgcggcccat gcggacaata
     5581 ttcggacaaa agaagagatt aaacgtcaga agcaggaacg cagtcataat cataactcaa
     5641 gagcagataa tgctgttgct gcagccagag cccagggacg ctacaccaca gatgatggtt
     5701 atatctttaa tgcttctgat atcattgagg acacgggtga tgcttatatc gttcctcacg
     5761 gcgaccatta ccattacatt cctaagaatg agttatcagc tagcgagtta gctgctgcag
     5821 aagcctattg gaatgggaag cagggatctc gtccttcttc aagttctagt tataatgcaa
     5881 at
//
LOCUS       DBEJZJ010000063         5743 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000063 DBEJZJ010000000
VERSION     DBEJZJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.63"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..558
                     /locus_tag="ACL3R8_001935"
     CDS             <1..558
                     /locus_tag="ACL3R8_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR1314741.1"
                     /translation="YAYSRYNFLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALN
                     HNWFLIFLYVGGGIPMNAWLMKGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPM
                     VAVQALWAFMGPFGDYILSSFLLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIA
                     LPICILFFFLQKNFVSGLTSGGDKG"
     gene            811..1611
                     /locus_tag="ACL3R8_001936"
     CDS             811..1611
                     /locus_tag="ACL3R8_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR1314742.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            1621..2607
                     /locus_tag="ACL3R8_001937"
     CDS             1621..2607
                     /locus_tag="ACL3R8_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR1314743.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(2898..3839)
                     /locus_tag="ACL3R8_001938"
     CDS             complement(2898..3839)
                     /locus_tag="ACL3R8_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR1314744.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3817..5580)
                     /gene="aspS"
                     /locus_tag="ACL3R8_001939"
     CDS             complement(3817..5580)
                     /gene="aspS"
                     /locus_tag="ACL3R8_001939"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR1314745.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT         1650 a         1356 c         1080 g         1657 t
ORIGIN      
        1 tatgcttaca gccgttacaa cttcttggct cgtaaacaaa gtttggtctt cttcttaatc
       61 atccaaatgg tgccaactat ggccgctttg acagccttct tcgttatggc gcttatgttg
      121 aacgccctta accacaactg gttcctcatc ttcctctacg ttggtggtgg tatcccgatg
      181 aatgcttggc tcatgaaagg ctacttcgat acagtgccaa tgtctttaga cgaatctgca
      241 aaactagacg gtgcaggaca cttccgccgc ttctggcaaa ttgttctacc acttgttcgc
      301 ccaatggttg ccgtacaagc tctctgggcc ttcatgggac ctttcgggga ctacatcctc
      361 tctagtttct tgcttcgtga gaaagaatac tttactgttg ccgtaggtct ccaaaccttc
      421 gttaacaatg cgaaaaactt gaagattgcc tacttctcag caggtgctat cctcatcgcc
      481 cttccaatct gtattctctt cttcttccta caaaagaact ttgtttcagg acttacaagt
      541 ggtggcgaca agggataatt tatccccgcc accctttttc attttatact cttcgaaaat
      601 ctcttcaaac cacgtcagct ttatctccaa cctcaaagtt gtgctttgag caacctgtgg
      661 ctagtttgca ctttgatttt cattgattat tagcaattgt cactgtaaat aatatccttg
      721 tagcaagcaa tttttctcct agacttgaaa taaagcgcat ttctctatat aataatactc
      781 atatagaaaa caccttttag aaagatacct atgcttccat atccattttc ctatttttca
      841 agtatttggg ggtttcgtaa gcccctgtcc aaacgtttcg agctcaactg gtttcaactt
      901 ctctttacca gtatcttcct tatcagcttg tctatggtac ccattgctat ccaaaacagc
      961 tcccaggaga cctatccgct agaaactttt atcgataatg tctatgaacc tctgacagat
     1021 aaggttgtcc aggatctctc tgaacatgct acaattgtcg atggcacatt aacttatact
     1081 ggaacagcta gtcaagcccc ttctgttgtg attggtccaa gtcaaatcaa ggaattacct
     1141 aaggacttgc aactgcattt cgatacaaat gaactagtca tcagcaagga aagcaaggaa
     1201 ctgacccgca tctcttaccg agccattcag actgagagtt tcaaaagcaa agacagcttg
     1261 acccaagcaa tttctaaaga ctggtaccaa caaaatcgtg tctatatcag cctcttccta
     1321 gttctcggtg cgagcttcct ctttggtttg aatttcttta tcgtctctct aggagctagt
     1381 cttctccttt atatcactaa gaaatcacgc ctcttttcat ttagaacctt taaagagtgc
     1441 tatcacttta tcttgaactg tttaggattg ccgactctga ttacacttat tttgggatta
     1501 tttggccaaa atatgacaac cctgattact gtacaaaata ttctttttgt tctgtatctg
     1561 gtcactatct tttataaaac acatttccgt gatccaaatt accataaata ggagattttt
     1621 atgcccgtta cgattaaaga cgtggccaag gctgctggtg tttcgccttc aaccgtaacc
     1681 cgtgttattc aaaataaatc aaccattagc gacgaaacaa aaaaacgcgt tcgcaaagct
     1741 atgaaggaac tcaactacca cccaaacctc aacgctcgta gcttggtaag cagctatact
     1801 caggttatcg gattagttct tcctgatgac tcagacgcct tctaccagaa tcctttcttt
     1861 ccatcggttc tacgtggcat ctctcaagtc gcatctgaaa accactatgc cattcagata
     1921 gcaacaggga aagatgagaa ggagcgtctc aacgctattt cacaaatggt ctacggcaag
     1981 cgtgtagatg ggctaatctt tctctatgcc caagaagaag accctctcgt aaaactcgtc
     2041 gcagaagaac agttcccctt ccttatccta ggtaaatctc tatctccttt catcccactt
     2101 gtcgacaacg acaatgttca agctggtttt gatgcgactg aatatttcat caaaaaaggc
     2161 tgcaaacgca ttgcctttat cggaggaagt aaaaagctct tcgtgaccaa agaccgttta
     2221 acaggctatg aacaggcgct taaacattac aaacttacca ctgacaacaa tcgcatctac
     2281 tttgccgacg agtttctgga agaaaagggc tataaattta gcaagcgatt attcaagcac
     2341 gatccacaaa ttgatgctat catcacaacc gatagcctcc tagctgaagg tgtttgtaac
     2401 tatattgcca aacaccagct ggatgtccct gttctcagct ttgactcggt taatcccaag
     2461 ctcaacttgg cagcctatgt cgatatcaat agtttagagc ttggtcgtgt ttcccttgaa
     2521 actattctcc agattattaa tgataataaa aacaataaac aaatttgtta ccgtcaattg
     2581 atcgcccaca aaattatcga aaaataagag actgggcaaa aagtcgttaa aagcaaaaac
     2641 gcatactatc aggtattgaa aaaacttgat actatgcgtt ttattgtggg aagatttact
     2701 tccttttctt ctgaaattga gttgttaccc aagatctttt tatactcaat aaaaatcaaa
     2761 gtgcaaacta ggaagctagc cgcaggttgc tcaaaacact gttttgaggt tgtggataga
     2821 actgacgaag tcagtaacat acctacggca aggcgacgct gacgtggttt gaagagattt
     2881 tcgaagagta ttaatcacta attatctatc tcaacaaatc ttcctagaat atgaacattt
     2941 tccgagacag agacaaagga gcttggatcc acttgtgtca taatctgttt aaattcatta
     3001 aactctgcac gtgtaatgac agtgattaaa actgcctttc tctcgtgatt ataggttcct
     3061 tctgcatcgt ggatcatggt tgctccgcgg tgcaattttt tatggatttt ttcaattacc
     3121 ttctctggat gatttgtcac aatcatggcc tgcatacgct tttgcttagt aaagactgcg
     3181 tctgtcacac ggctagagac aaagatggta atcatagaat aaagagcgta tttccaacca
     3241 aaggtcaaac ctgctatcag catgatagtt ccatttacca agaaagaaat actaccgaca
     3301 ttcttacccg ttttcttgcg aatagtcagg ctgacgatat ccgtcccacc actggagata
     3361 ttgtttcgaa gagcaaaacc aatccccaaa cccataacaa cacccccaaa aagggaattg
     3421 ataatgggat cctccgtcaa ggttgccaca gggacaaact ggataaagaa ggaactcata
     3481 gataccgtga taaaggtaaa gacggtgaac ttatggccaa tctgatacca agctaagacc
     3541 atcaaaggga agttaatggc gtagaagctt agcgaaatcg gaatatgaaa accaaaccag
     3601 tgattactca aggcagagat aatctgtgcc agacctgttg caccactcga atacacatgc
     3661 cctggttgga aaaagaaatt aactgctact gctgataaaa aaccatagac cagagaggcc
     3721 gaaatcttct catcatactt ttctcgagag atactttgta agacacgtaa aatttttatc
     3781 tgataagcaa agcggcgcag ataatagcgc caccgcttaa ttcgttttgt ttgtttcatc
     3841 ttcttctact tgtaagctga gttcctctag ttgtttgaga gcgactgttg atggagcttg
     3901 tgtcattgga tcagttgcct tgttgttctt aggaaaggca atgacttcac ggatattttc
     3961 ttctccagca agcaacatga caaaacggtc aagcccgata gccaaaccac cgtgtggtgg
     4021 gaaaccatag tccatggctt caagaaggaa accaaactgg tcattggctt cttcagctga
     4081 gaaaccaaga gccttgaaca tgcgttcttg aaggtctttt tggttgatac gaaggctacc
     4141 accaccaagc tcataaccgt tcaagacgat atcgtaagca atggcacgaa ccttagccaa
     4201 atcaccttct aattcgtgag cagtctcttc ctgtggaagt gtgaatggat ggtgggcgct
     4261 catgtagcgg ccttcttctt cagaccattc aaacatcggc cagtcaacca cccaaaggaa
     4321 gttgaactta tcattatcaa tcaagccaag ctctttagca atacgtccac gaagggcacc
     4381 cagtgttgca ttagccactt caagcgtatc cgccacaaag agaaccaagt ccttatcttc
     4441 aagagcaagc gctgttgtca attcttcttg gataccagtc aagaacttgg caactggtcc
     4501 gtttaattct ccatcaacca ccttgaccca agcaagacct ttggcaccat actgtttggc
     4561 tacttccgtc atcttgtcga tgtctttacg tgaatagttg tccgcagctc ctttgaccac
     4621 aatcgctttt acagcaagtg cttctgaaaa gactttaaag tctacacctt tgaccacttc
     4681 tgtcaagtcc tgaagcaaca tgtcaaaacg agtatctggc ttgtcagaac cgtaaagagc
     4741 catagcatca tcgtatttca tacgagggaa cggtagcgtt acttcgatgc cttttgtttc
     4801 cttcatcaca cgcgcgatca agccttctgt aatatcttgg atttcttgct cagtaaggaa
     4861 ggacgtttcc aagtcgacct gagtaaattc aggctggcgg tctccacgca agtcctcgtc
     4921 acggaaacat ttaacgattt ggtagtaacg gtcaaaacca gcattcatca agagctgttt
     4981 cgtgatttgt ggactttgag gaagagcgta aaaatgcccc ttattaacac gagacggcac
     5041 taaataatca cgcgcccctt caggcgttga cttagaaagg aatggtgtct ccacgtcgat
     5101 aaactccaac tcatccaagt agttgcggat agagtgggtc accttggcac gaagtttaag
     5161 attttccaac atttctggac gacgaaggtc aaggtaacgg taacgcaaac gtgtatcgtc
     5221 atttgcctca atgccatcct taatctcaaa tggtgttgtc ttagctgtgt taagcacaat
     5281 aagagctgtc acgtttaact caaccgcacc agttggcaac ttatcattgg cttgctcacg
     5341 cgcagcgacc tgaccagtca cctcaataac aaattcgcta cgaaggcttt cagctgttgc
     5401 cataacctct gcagatactt tttcagggtt gataaccaac tgcatgattc cttcacggtc
     5461 acgaagatcg ataaagatca aaccaccaag gtcacgacga cggccaaccc atcctttcaa
     5521 ggttatttct tgtccgatgt gttcctcacg aacacgacca gcatacatac tacgtttcat
     5581 tatttctctc ctcttttatt ctgttactat tttaccataa aagcgcaggc tcttcatgaa
     5641 aatcatcaga aaagtttgcc agtctttaaa agtcaggtga aagccctaaa aattagcgct
     5701 aatgctcttc gaaaatctct tcaaaccacg tcagcgtcgc ctt
//
LOCUS       DBEJZJ010000064         4790 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000064 DBEJZJ010000000
VERSION     DBEJZJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.64"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(173..1588)
                     /locus_tag="ACL3R8_001940"
     CDS             complement(173..1588)
                     /locus_tag="ACL3R8_001940"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR1314746.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="ACL3R8_001941"
     CDS             complement(1601..3439)
                     /locus_tag="ACL3R8_001941"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR1314747.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAASFSALLAGITEPAVYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGIELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /gene="licT"
                     /locus_tag="ACL3R8_001942"
     CDS             complement(3457..4296)
                     /gene="licT"
                     /locus_tag="ACL3R8_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR1314748.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFVALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..>4790)
                     /locus_tag="ACL3R8_001943"
     CDS             complement(4597..>4790)
                     /locus_tag="ACL3R8_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HGR1314749.1"
                     /translation="SSQLKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEM
                     TILRLESASIVSELVAGLR"
BASE COUNT         1603 a          933 c          623 g         1631 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtaccttt
      301 tagaaagttg tgcagtggac atagaaacac agtcaataca tccccaagac gtatagccca
      361 taatttcaac accatcctgt agagcttcag caacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg acggttaagt tattaagttc atcttttatt agttgatctt
      481 tagcacctaa tccattttct actataaata atgggatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactctgaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggttatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaataccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggga taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaatg accgccacaa
     2161 ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 ctgcaggttc ggtaatccct gcaagtaagg ctgagaaact tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggtccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaatagc tggtgttaat ttagcaatta
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gatgaaccat
     2821 aactagctgg tgtcacaggt gcaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaatgattac caagactttc aacatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccgtatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactccgt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta cgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctaga ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc caatttttct
     4201 tccaaaagct atgccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tgtgaactac
//
LOCUS       DBEJZJ010000065         4412 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000065 DBEJZJ010000000
VERSION     DBEJZJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.65"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(97..1386)
                     /gene="hisS"
                     /locus_tag="ACL3R8_001944"
     CDS             complement(97..1386)
                     /gene="hisS"
                     /locus_tag="ACL3R8_001944"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR1314750.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1464..2711)
                     /locus_tag="ACL3R8_001945"
     CDS             complement(1464..2711)
                     /locus_tag="ACL3R8_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR1314751.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGSQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(2901..3752)
                     /gene="rgg"
                     /locus_tag="ACL3R8_001946"
     CDS             complement(2901..3752)
                     /gene="rgg"
                     /locus_tag="ACL3R8_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR1314752.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3876..4217
                     /locus_tag="ACL3R8_001947"
     CDS             3876..4217
                     /locus_tag="ACL3R8_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR1314753.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1390 a          930 c          866 g         1226 t
ORIGIN      
        1 cgtaggtatg gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc
       61 aacctgcggc tagcttccta gtttgctctt tgatttttat tgagtataaa atcctagttt
      121 ttcaaagatt tctgagaagt tttggctgat tgtctcaagt gacacttgca cttcttctcg
      181 agtttggttg ttcttgaccg tcacttgtcc gctttcgact tcgctctctc ctagggtgat
      241 gagggtctta gccacaaaga catcggctga cttgaactga gcttttagtt tacggttgag
      301 gtaatcacgc tctgctttga aaccttgttg gcgaagagcc tgtaccaatt ccaaggcctt
      361 gatatttgcc ccttcgccca agactgcgat atagacatct agggcgtttt cgatagggag
      421 ggtcacgcct tgtttttcaa ggatgagaag caggcgctct acaccaagtc caaaaccaaa
      481 tccagcagtt tcagggcctc caaagtaagc aaccaaacca tcgtagcgac cacccgcaca
      541 gactgtcaag tcattgccct caatctctgt gataaactcg aaaatggtgt ggttgtagta
      601 gtccagacca cgcaccatat tggtatcgat gatgtaatct actccaagat tttccaacat
      661 ctgacgcaca gcatcaaaat gagtttggct ttcttcatca agaaagtcca agatagacgg
      721 cgcattctct actgccacct tgtcttcttt ttccttagag tccaagacac gaagaggatt
      781 ttcctccaag cgacgttggc tatccttaga caaggtctcc ttgagcggtg tcaaatagtc
      841 aatcaaggct tggcggtagg ctgcacggct ctcaggattt ccaagagtgt tgaggtgcaa
      901 tttgacacct tgaataccga tttccttcaa aaaatgggct gccataacga ttgtttccac
      961 atcggtagct ggattgctag agccaaaaca ctcaacacca atctggtgga attggcgcaa
     1021 gcgccctgcc tgtggacgct cataacggaa cataggtccc atgtagtaga acttgcttgg
     1081 cttttgcact tctggggcga agagtttatt ttccacatag gaacggacaa cgggcgcagt
     1141 tccttctgga cggagggtaa tatggcggtc acccttgtca tagaaatcgt acatttcctt
     1201 ggttacgata tccgttgtat ctccgacaga gcggctgata acctcgtaat gctcgaaaat
     1261 aggcgtacgc acttctgcgt agttgtagcg cttgaaaatt tcacgggcaa agccctcaac
     1321 gtactgccac ttagcagact cagcaggtaa aatatcctgc gttccttttg gtttttgtaa
     1381 tttcataggg aatcctcttt aaacttaata gtcttatttt accataaata gagggattaa
     1441 aacagtaaga aaaaaattag gatttagata tcatttttga gattaagaat tgttaaaaaa
     1501 atagctagca aggaaaaacc aacaaatagc atccaagtca actgcatgtt ccatacggct
     1561 actagtgaaa aacaagctgt tcccacaggt atggataagg taaacaatag accgaaaaaa
     1621 ttactagtac gagctagaac ctctggagct agatttttca tgagcatggc actaatcttt
     1681 ggttgaactt taccagacac atacagagta aagaagagaa atagcaaacc aagcacgact
     1741 tgattgaata aattagccaa accaactaga ctaagtccta cggtctccca catcatcaat
     1801 ctaggcaagg actgcttccc aaaataatca ttgcccgtaa ggctactgat gatgattgct
     1861 actaaaacac agaattgatt gataaatagt gcctctgtat aagaaaaatt caagagagaa
     1921 tggctcaaaa agaagatatt ataaattcca cccaaagcgc cacccaagga attaataagc
     1981 aagacagcaa agagcataaa accaaagttt ttctgtccac ttttaagaaa aacgagacgt
     2041 aaatttcggt aaattgttag gaaccggtct ttgatagaaa gcttctcatt ttttaagttt
     2101 tcaccatcag cagatgacat tgacaggctc aatttgcttt ttcctaaaaa gaggatagtg
     2161 gctgatacta ggaaaaagca ggcattgatt cccgcaacga gagaaaaatt attgaccgat
     2221 agagctaaga gccagactcc gaaagcttga ctaccaatag ctgaaatata ggtgatgaac
     2281 tgtgaaaaag aataagcctc catcaaatca tcttcagcta ctttttcctt aataagaggc
     2341 atacgcaggc cacctgcaaa atcactgatg acatcactaa tgacattgat caaacacagg
     2401 ctagaaaagg caaagagact agcttgctga acaactaggg ctgctagaaa aaatagaacc
     2461 gcctgaaaca aaccgctata gaccatccat ttgaccttgt ccctcgtgta atctgcccga
     2521 atccctgcaa aaactgtaaa gagggtcgga agaatcatga caatattcgc catagcaaca
     2581 gcaaaagatg cttgtggcaa ggtcgatgca tagacgataa agaccaggtt gaaaatcgaa
     2641 gcaccaaaag cattgaagaa gcgtgacaaa gtcaataggc gataagcttg atttctaaac
     2701 aatagtttca tagataatct ccctccttgt tctaagttct acatcaagaa tagctttagt
     2761 atagcactta tgaatttgcg aaacaattct tttgaatata tgcaacaaat aaaatgagca
     2821 aaaaacgata gaacttttgt aatgacctga gaaagggcaa cagttctatc gcttcaaatt
     2881 ttttcttagt ttgcagatat tcaacattcg gtcgtatttc tatagtattc ggcagattta
     2941 ttacagccaa gcatctcaaa aatacggaca gcatcctcca tctttttctg gccttccttg
     3001 actctacctt gcttgctatc aaggagacct tctgcccaca gataaacaat tcggaaatag
     3061 gtctcatttt ccttgtagaa atgctcttcg ataacacgtt taaaataata ggcattggta
     3121 aattcttcac actcaatact agctaaaaag ccattcaata gtatagtatg aaaaaggttt
     3181 cgattgccag acatttccat tagaaaatca gatttacgta ccatttctcg tacatatcta
     3241 gtaaaaagag aaacagataa aaatggagaa ctgactgaaa ataaattgag tttatagatt
     3301 ccccagatct cggtagaaaa caaataatca tgaaggactt ttccttcctc tgctgttaac
     3361 tctacccttt catccatgct cttcatataa gacttgatca taatggcatt tagaatatgt
     3421 ttctgtttgt tgtgagaatg ggcatgcttt tgatactccc tgcgatataa gtcctcaaga
     3481 ggtgctatat tctttggttc caagacatct gtaatttctt ttctcaactc agaatctgta
     3541 tcatactgga aacctctcgc cagaaagagg atctcctcca cactggcaga tatattttcc
     3601 agagcaaata gaaacttttc caccgaaagc tcactctgac ctgtttcaaa acgggacaac
     3661 atagacggcg aaaattgtcc tccggttgct tgtctcagtg agatatttct tgattctcgt
     3721 aattgtctaa agacttttcc aatctgctcc atagacttcc ccttgatccc gtattttctt
     3781 cattttatca tatttttcag aaaattcatc aaaaacttgc caaattgtca gaatcatgag
     3841 aaaatagagg atatttatca cgtggaggga ctgctatgag agacgatatc aaaatcaatg
     3901 accgtgcttt ggccttgcaa gaccaaatta tcgaaaaact agagaaagtt tttgatacag
     3961 atgtggaatt ggatgtttac aatctaggtc tgatttatga aatcaatctg gatgaaacgg
     4021 ggctctgcaa gattgtcatg accttcaccg atactgcctg tgattgcgcc gaaagcctgc
     4081 ctattgaaat cgtggcaggt ctgaaacaaa tcgagggtat caaagatatc aaggttgaag
     4141 ttacctggtc gcctgcttgg aaaatcacac gaatcagtcg ctatggccgt attgcccttg
     4201 gactaccacc tcgttaagca ggccaatcac ttttaaagat gaaaaaagca agccgaaaat
     4261 ggcttgcttt ttgatactca atgaaaatca aagggcaaac tagaaaacta gccgcaggtt
     4321 gctcaaaaca ctgttttgaa gttatggata gaactgacga agtcagctca aaacactgtt
     4381 ttgaggttgt ggatagaact gacgaagtca gc
//
LOCUS       DBEJZJ010000066         4394 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000066 DBEJZJ010000000
VERSION     DBEJZJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4394
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.66"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            89..1168
                     /locus_tag="ACL3R8_001948"
     CDS             89..1168
                     /locus_tag="ACL3R8_001948"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314754.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSEIERVYANLWTVA"
     gene            1113..2090
                     /locus_tag="ACL3R8_001949"
     CDS             1113..2090
                     /locus_tag="ACL3R8_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314755.1"
                     /translation="MSFILKLRGFTLTYGQWRKEFQSRFFPVHYYGLNFNQGIAFSDL
                     AILWSYQQLAKKVKNFKFDDYYEIRTQVINEAVNNFKKSSLSGLFDDKIGTIWLIYEF
                     GEIDRAVELFTTHFIEIFENSQNKNLYSGQVSIDFSFKSPFRVLLTGTSGSGKTTILN
                     LINGSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQII
                     EVLKKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISAN
                     LDNDNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            2105..2845
                     /locus_tag="ACL3R8_001950"
     CDS             2105..2845
                     /locus_tag="ACL3R8_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR1314756.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            2848..4167
                     /locus_tag="ACL3R8_001951"
     CDS             2848..4167
                     /locus_tag="ACL3R8_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR1314757.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            4300..>4394
                     /locus_tag="ACL3R8_001952"
     CDS             4300..>4394
                     /locus_tag="ACL3R8_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR1314758.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT         1512 a          545 c          811 g         1526 t
ORIGIN      
        1 gaatccaaag gattctccct ttttatttaa ataagtctgt ctagctatag atatattaag
       61 tttgataaaa tttcttggag attttgttat ggattataat ttcaatttgg agcatccttt
      121 ctttttcact aataatgatt atagtacaga tactagcata aagtaccaag taagtctgcc
      181 ttttaattgg cacgaagtaa tgaataatga tgagtgggtt tatcaatacc ctattggaaa
      241 atttgttgaa agacaagggt ggaaaataca cattagttca gagtataaca gttcacatga
      301 attgttacaa gatgtagcaa aaatttgcca tgaaatgcga attccattta aacatcttag
      361 tacagaagac aaatttatca tgcgaaacgg gaaattggtt agtcgaggat tttctggtaa
      421 atttattaca tgttatccaa atcaaaatga attagagtcg gttttgcaaa ggttagaaag
      481 tgccttaaag caatataatg ggccatatat tttaagcgat aaacgttggg atgaagcacc
      541 aatatatctg aggtatggtg tgtttaggcc gtcaagggat gatgaaaaga aggttgctat
      601 tgatgaatta attgttggcg atgaagttgt taaagatgaa cgtttaccag tatttaaaat
      661 tccaaaaggt atagtgcccc ctgacttttt gaataaatgg cttgacaaga aagataaaaa
      721 acagggagac tttcccttta ttatagataa tgcaattaga ttttcaaaca gtggtgggat
      781 atataatgct aggctaaaag aagatgggaa aaaaataatt ttaaaagagg ctagaccgta
      841 tacaggtcta ggatttgatg gtacttattc ttcagagaaa ttagcttcgg agtgcaaagc
      901 actaaaaatt ctaaatgaat ggagtgagac gcctaaaata tactggcacg gtaagatctg
      961 ggagcacacc ttcttaggaa ttgaacatat gaagggcgtt ccactaaata gatgggttac
     1021 caataatttt cctttatatg aagttgttga taagaccaaa gattatctat tgagagtttc
     1081 aaagatagta gaaaaactca tcgatttaac gaataagttt cattctgaaa ttgagagggt
     1141 ttacgctaac ttatggacag tggcgtaaag aatttcaatc aagattcttc ccagttcatt
     1201 attatggtct gaattttaat caaggaattg cgttttcaga tttagctatc ctttggagtt
     1261 atcaacaact agctaagaaa gtaaaaaatt tcaagtttga tgactattat gagattcgaa
     1321 cacaggttat taatgaggca gtaaataatt ttaagaaatc gtccctttct ggtctttttg
     1381 atgataaaat tggtacaatc tggctcattt atgaatttgg ggagatagat cgggcagttg
     1441 aactttttac aactcatttt atagagatat ttgagaattc acaaaataaa aatttatata
     1501 gtgggcaggt aagtattgac ttctcattta agtcaccatt tagggtatta ttaacaggaa
     1561 cttctggcag tgggaaaaca acgattttaa atttaattaa tggttcttta aagccacaaa
     1621 aaggttatgt aaatttgtta tcacatggga aaaagagttc agattcaata ccaacagttg
     1681 atcagacacc atatattttt gacactacta ttcgtgagaa cgtaacttta tttcaaaatg
     1741 aatatttttc agatgatcag ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat
     1801 tagaaaagat agatatacta aattatcaat gtggtgaaaa tggtagtaat ttgtctggag
     1861 gtcaaaaaca aaaaatagct ttagctagag ctctgattag aaataataaa gtgtacttat
     1921 ttgacgaaat atcagctaat ttagataatg ataattcaaa ttccatacat gatattctgt
     1981 tcaatttagg tatttcattt attgaagttt cacatcatta tgacttaaat gacaagagat
     2041 acactgatat atataaattg gaaaatggaa cacttttcaa aattaagtga ttggaggcaa
     2101 gaatatggat aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg
     2161 aaataataaa acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt
     2221 tataagtatt ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag
     2281 tttgcttgaa ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag
     2341 aaatgcaaaa ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa
     2401 tttaatacct tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa
     2461 aaaattaact attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt
     2521 aaacgatttt gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc
     2581 ggttattgct gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt
     2641 ttctcgtgaa gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat
     2701 tatggtaacg cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga
     2761 tggaaaaatt ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga
     2821 ggtacaatca actacggagg aatagagatg ctcagattag tttactatca atttttacat
     2881 aataagaaac aatggttagg cgtttcacca gtaatttttg tttcgagttt agttatggga
     2941 ttggctgtta atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca
     3001 gatcctaaac caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg
     3061 ctctctaaca taataaatat gttggttgaa atttttagag atgattacga acttttggag
     3121 gtgttgggag caagtcgcct tcaactatca tttcttgtgg ggggacagat ttttatcatt
     3181 tcctcgatta ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat
     3241 tattttttac aatacttttt cggggaaaat atattacctg atatccaatt tcaaacgagt
     3301 gctgttggat gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc
     3361 ttttatacgt tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca
     3421 atagtaaaaa gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa
     3481 caaattttcc aagatagcac aattttagcg aaggcccaga taatattcaa tattgtaatc
     3541 ttagatattg tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta
     3601 ctttctataa ttatatttag aaataatttt atgttcattg tttcgaagtg gaatttacta
     3661 tattgtaagt cttatataaa atctatcagt gctgcaatta caggagctat attactaatt
     3721 tctagttttc aaatgatttc tcagaatata ctatctcaat ttcaagatga cagtgattta
     3781 gagctaaaag tagcatttat tgtctatgta ggagcaccaa ttttgatagt acttgcaaat
     3841 attatttcaa ttgcattttt gtcatcgcat caagaaagga ttgagattca gcaatttgaa
     3901 attttaggaa cttctaatta ccagatggtt aagattaaag ttggtgaggc tatatttttg
     3961 acatttgtta cttcattaat tgcattttta cttaacatta aaattatggc tttaatatac
     4021 tactctttag aggatatttt aatagatgat atgaatcttt tggggttaat acttccaaat
     4081 tttatagtat ctattatttt atttatttta atatttatta ctaaaagttc ctattttatc
     4141 tttaagaatg caaaaattat ttcttaaaaa tttgtaagtt ttcgctatat aaaatagtta
     4201 aatctatttt gtatcattgc ttgcatttta ctggtggaga gagtatatga gggtggataa
     4261 agtacttaat cccaaaaatt taaataggag gagctagcta tggcagcaga agtattaaat
     4321 cttcaattag tatctgttca agttgacgaa acagatgaag ttgatggaat gcgatttagt
     4381 acattcagta caaa
//
LOCUS       DBEJZJ010000067         4383 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000067 DBEJZJ010000000
VERSION     DBEJZJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.67"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            289..1668
                     /locus_tag="ACL3R8_001953"
     CDS             289..1668
                     /locus_tag="ACL3R8_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR1314759.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            1682..2347
                     /locus_tag="ACL3R8_001954"
     CDS             1682..2347
                     /locus_tag="ACL3R8_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR1314760.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            2702..2875
                     /locus_tag="ACL3R8_001955"
     CDS             2702..2875
                     /locus_tag="ACL3R8_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR1314761.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGWDQVGNFSKGQYIMMHS
                     LIYRTDLLRASQF"
     gene            2942..3352
                     /locus_tag="ACL3R8_001956"
     CDS             2942..3352
                     /locus_tag="ACL3R8_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR1314762.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            3468..>4383
                     /gene="pavB"
                     /locus_tag="ACL3R8_001957"
     CDS             3468..>4383
                     /gene="pavB"
                     /locus_tag="ACL3R8_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR1314763.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT         1239 a          833 c          964 g         1347 t
ORIGIN      
        1 ctatttgcaa cctcaaaaca gtgttttgag caacctgtga ctagctttct aatcgatgcc
       61 ttggttttca ttgcctataa tcaaaaagag aaattttctc ctgaaaagca tatagagtag
      121 ctggcgttaa aagctcctgt cttgcttttt tgacctatag tcacatctat caagtattgt
      181 tcttgcctaa gctatcaata aaaaggtggc attttttagg cttggtgtta gtagattttg
      241 ccttatccta tctaagtcat ttcgaacttt ttatggtaca atggaaacat gttattcaaa
      301 ttatctaagg aaaaaataga gctaggctta tctcgtttat cgccagcccg tcgtattttt
      361 ttgagttttg ccttggtcat tttactaggc tctcttcttt tgagcttgcc ctttgtccaa
      421 gttgaaagct cacgagcgac ttattttgat catcttttca ctgctgtatc tgcagtctgt
      481 gtgacgggtc tctcaaccct tccagtagct cacacctata atatctgggg tcaaataatc
      541 tgtttgctct tgattcagat cggtggtcta gggctcatga cctttattgg ggttttctat
      601 atccagagca agcaaaagct tagtcttcgt agccgtgcaa ctattcagga tagttttagt
      661 tatggagaaa ctcgatcttt gagaaagttt gtctattcta tttttctcac gacctttttg
      721 gttgagagct tgggagctat tttgcttagt tttcgcctta ttcctcaact tggctgggga
      781 cgtggtcttt ttagttccat ttttctagcg atctcagcct tctgtaatgc cggttttgat
      841 aatttaggga gcaccagttt atttgctttt cagaccgatt tactggtcaa tctggtgatt
      901 gcaggcttaa ttattacagg cggccttggt tttatggtct ggtttgattt ggctggtcat
      961 gtaggaagaa agaaaaaagg acgtctgcac tttcatacga agcttgtact attgttgact
     1021 ataggtttgt tgttatttgg aacggcaact actctctttc ttgagtggaa caatgctgga
     1081 acgattggca atctccctgt tgccgataag gttttagtta gcttttttca aacagtgacg
     1141 atgcgaacag ctggcttttc tacgatagat tatactcagg ctcatcctgt gactcttttg
     1201 atttatatct tacagatgtt tctaggtggg gcacctggag gaacagctgg gggactcaag
     1261 attacgacat tttttgtcct cttggtcttt gcacgaagtg agcttctagg cttgcctcat
     1321 gccaatgttg cgagacgaac gattgcgccg cgaacggttc aaaaatcctt tagtgtcttt
     1381 attatctttt tgatgagctt cttaatagga ttgattctgc tagggataac agccaaaggc
     1441 aatcctccct ttatccacct catatttgaa accatttcag ctcttagtac agttggtgta
     1501 acggcaaatc tgactcctga ccttgggaaa ttggctctca gtgttatcat gccacttatg
     1561 tttatgggac gaattggtcc cttgaccttg tttgttagct tggcagatta ccatccagaa
     1621 aagaaagata tgattcacta tatgaaagca gatattagta ttggttaaga aaggaaagag
     1681 catgtcagat cgtacgattg gaattttggg cttgggaatt tttgggagca gtgtcctagc
     1741 tgccctagcc aagcaggata tgaatattat cgctattgat gaccacgcag agcgcatcaa
     1801 tcagtttgag ccagttttgg cgcgtggagt gattggtgac atcacagatg aagaattatt
     1861 gagatcagca gggattgata cctgcgatac cgttgtagtc gcgacaggtg aaaatctgga
     1921 gtcgagtgtg cttgcggtta tgcactgtaa gagtttgggg gtaccgactg ttattgctaa
     1981 ggtcaaaagt cagaccgcta agaaagtgct agaaaagatt ggagctgact cggttatctc
     2041 gccagagtat gaaatggggc agtctctagc acagaccatt cttttccata atagtgttga
     2101 tgtctttcag ttggataaaa atgtgtctat cgtggagatg aaaattcctc agtcttgggc
     2161 aggtcaaagt ctgagtaaat tagacctccg tggcaaatac aatctgaata ttttgggttt
     2221 ccgagagcag gaaaattccc cattggatgt tgaatttgga ccagatgacc tcttgaaagc
     2281 agatacctat attttggcag tcatcaacaa ccagtatttg gataccctag tagcattgaa
     2341 ttcgtaaaga gggatgaccc ctcttttttg atgcccaaga tggcaaatag agacagaagc
     2401 cccttgtctt ctagtaaaag ttcttcaaag gctggacttt atggtaaaat agaaggaagt
     2461 gacaagagag agtaatactc aatgaaaatc aaagatcaaa ctaggaaact agctacgggc
     2521 tgcttaaaac actgttttga ggttgtggat agaactgacg aagtcagctc aaaacactgt
     2581 tttgaggttg cagatagaac tgacgaagtc agtaacatct atacggcaag gcgatgttga
     2641 cgcggtttga agagattttc gaagagtata agaaaaaatc agtcccctaa aggagcagat
     2701 tatgaagtta ttgtctatcg ccatttctag ctataatgca gcagcctatc ttcattactg
     2761 tgtggagtcg ctagtgattg gctgggacca ggtcggaaat ttctccaaag gccagtatat
     2821 catgatgcac tcgctgattt atcggacaga tttgttgcgt gctagccagt tctaattgcc
     2881 tgaacatact ttttatgtcg ataatctctt tgtctttacg ccccttcagc aggtcaagac
     2941 catgtactat ctgcctgtcg atttctatcg ttatttgatt gggcgtgagg gccagtctgt
     3001 caatgagcaa gtgatgatta agtgcattga ccagcaactc aaggtcaatc gactcttggt
     3061 agaccagctt gatttgtccc aagtgagtca tcccaaaatg cgagaatatc tgctgaatca
     3121 tattgaaatc acgacggtga tttccagtac cctgctcaac cgatctgaaa cagcggagca
     3181 tctggcaaaa aaacgccaat tgtggaccta tattcagcag aaaaatccag aagtctttca
     3241 ggctattcgt aagaccatgt tgagccgttt gaccaaacat tctgtcttgc cagatcgcaa
     3301 actgtccaat gtcgtctatc aaatcaccaa atctgtttat ggatttaatt aatataagtg
     3361 ttttataaga gggatttaag aaaaatttta actttttctt agtccttttt aatttcagga
     3421 gattatacta gagtcatcaa ataaagaaag actctaagga gaatcctatg aaattcaatc
     3481 caaatcaaag atatactcgt tggtctattc gccgtctcag tgtcggtgtt gcctcagttg
     3541 ttgtggctag tggcttcttt gtcctagttg gtcagccaag ttctgtacgt gccgatgtgg
     3601 tcaatccgac cccaggtcaa gtcttacctg aagagacatc gggaacgaaa gagggtgact
     3661 tatcagaaaa accaggagac accgttctca ctcaagcgaa acctgagggc gttactggaa
     3721 atacgaattc acttccgaca cctacagaaa gaactgaagt gagcgaggaa acaaactctt
     3781 ctagtctgga tacacttttt gaaaaagatg aagaagctca aaaaaatcca gagctaacag
     3841 atgtcttaaa agaaactgta gatacagctg atgtggatgg gacacaagca agtccagcag
     3901 aaactactcc tgaacaagta aaaggtggag tgaaagaaaa tacaaaagac agcatcgatg
     3961 ttcctgctgc ttatcttgaa aaagctgaag ggaaaggtcc tttcactgcc ggtgtaaacc
     4021 aagtaatccc ttatgaacta ttcgctggtg atggtatgtt aactcgtcta ttactaaaag
     4081 cttcggataa tgctccttgg tctgacaatg gtactgctaa aaatcctgct ttacctcctc
     4141 ttgaaggatt aacaaaaggg aaatacttct atgaagtaga cttaaatggc aatactgttg
     4201 gtaaacaagg tcaagcttta attgatcaac ttcgcgctaa tggtactcaa acttataaag
     4261 ctactgttaa agtttacgga aataaagacg gtaaagctga cttgactaat ctagttgcta
     4321 ctaaaaatgt agacatcaac atcaatggat tagttgctaa agaaactgtc gaaaaagctg
     4381 tta
//
LOCUS       DBEJZJ010000068         4130 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000068 DBEJZJ010000000
VERSION     DBEJZJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.68"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            67..312
                     /locus_tag="ACL3R8_001958"
     CDS             67..312
                     /locus_tag="ACL3R8_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314764.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            713..1705
                     /locus_tag="ACL3R8_001959"
     CDS             713..1705
                     /locus_tag="ACL3R8_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR1314765.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="ACL3R8_001960"
     CDS             1707..2525
                     /locus_tag="ACL3R8_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314766.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="ACL3R8_001961"
     CDS             2527..3312
                     /locus_tag="ACL3R8_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR1314767.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="ACL3R8_001962"
                     /pseudo
     CDS             3351..3629
                     /locus_tag="ACL3R8_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
     gene            3566..3811
                     /locus_tag="ACL3R8_001963"
     CDS             3566..3811
                     /locus_tag="ACL3R8_001963"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR1314768.1"
                     /translation="MSRRKKAYQGRKIGSQLLATLESEAHKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1155 a          696 c          891 g         1388 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattataaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcattctgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaataca atgttgctat tccttatgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccaga acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcgaact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcatgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgttttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cataagccta tataaaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactgg atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cataaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcttcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc taatattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt
//
LOCUS       DBEJZJ010000069         3457 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000069 DBEJZJ010000000
VERSION     DBEJZJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.69"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            166..591
                     /gene="rplK"
                     /locus_tag="ACL3R8_001964"
     CDS             166..591
                     /gene="rplK"
                     /locus_tag="ACL3R8_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR1314769.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            799..1488
                     /gene="rplA"
                     /locus_tag="ACL3R8_001965"
     CDS             799..1488
                     /gene="rplA"
                     /locus_tag="ACL3R8_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR1314770.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1577..2883)
                     /locus_tag="ACL3R8_001966"
                     /pseudo
     CDS             complement(1577..2883)
                     /locus_tag="ACL3R8_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3179..3337
                     /locus_tag="ACL3R8_001967"
                     /pseudo
     CDS             3179..3337
                     /locus_tag="ACL3R8_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         1092 a          609 c          756 g         1000 t
ORIGIN      
        1 cggctagctt cctagtttgc tctttgattt tcattgagta taaaaaataa acttttctct
       61 tgcaattcca gataaatagt gtataatgaa tgggtatgcg aaaaacatac ttgtgggagg
      121 taaaaatctc taattaccgc caaaaccaca aaggaggatt taaaaatggc taaaaaagtc
      181 gaaaaacttg taaaattgca aatccctgct ggtaaagcta caccagctcc accggttgga
      241 cctgctcttg gtcaagctgg tatcaacatc atgggattca caaaagagtt caacgctcgt
      301 acagctgacc aagctggtat gatcattcca gttgttatct cagtttacga agataaatca
      361 tttactttcg ttacgaaaac accaccagct gctgttcttt tgaaaaaagc tgcaggtgtt
      421 gaaaaaggat caggtacacc taataaaact aaagttgcta cagttactcg tgcacaagta
      481 caagaaattg cagaaactaa gatgccagat ttgaacgcag caaacgtaga gtctgcaatg
      541 cgtatgatcg aaggtactgc tcgttctatg ggattcactg ttgttgacta atcaataaca
      601 cagtagaaaa tctcacagca gtctattagt tgcttttcat actaggcaag tgactgaggc
      661 ttgtacttgg gtacagcaag ggagcttaag gccgtaggaa gagaaaaata gtagactgaa
      721 aacccgcaag acttcatcat ttcgagaagt gacgtgggag atgaaaatcg attgaaccac
      781 ttacaaggag aatagaaaat ggctaaaaaa agcaaacaac ttcgtgctgc tcttgagaaa
      841 atcgacagca caaaagcata cagcgtagaa gaagctgtag cacttgcaaa agaaactaac
      901 tttgcaaaat ttgacgcaac tgtagaagtt gcttacaact tgaacatcga cgttaaaaaa
      961 gctgaccaac aaatccgtgg agcaatggta ttgccaaacg gtactggtaa aacttcacgt
     1021 gttcttgttt tcgcacgtgg tgcaaaagct gaagaagcaa aagctgctgg tgcagacttt
     1081 gttggtgaag atgaccttgt tgctaaaatc aacgacggtt ggttggactt cgacgtagtt
     1141 atcgctacac ctgatatgat ggctcttgtt ggacgtcttg gacgtgtcct tggaccacgt
     1201 aacttgatgc caaaccctaa aactggtact gtaacaatgg atgttgctaa agcagttgaa
     1261 gagtctaaag gtggtaaaat cacttaccgt gctgaccgtg caggtaacgt tcaagcaatc
     1321 atcggtaaag tatcatttga agctgaaaaa ttggttgaaa actttaaagc tttcaacgaa
     1381 acaatccaaa aagcaaaacc agctacagct aaaggaactt acgtaacaaa cttgactatc
     1441 acaactactc aaggtgttgg tatcaaagtt gatgtaaact cactttaatc agtagttaaa
     1501 gtaatgtaaa aaagttgaag acgctatgtc tcaacttttt ttggctcttt gtcaactgta
     1561 gtgggttgaa aaaaagctaa gctcgagaaa ggacaaattt tgtcctttct tttttgatat
     1621 tcagagcgat aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc
     1681 gcttgataag tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt
     1741 gaagggcgtt gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa
     1801 taggatgagc ctgcttaaga ttgtcctcaa taagtccgaa aaatttctct ggttccttat
     1861 tctggaagtg aaaaagcaag agctgataga gctgatagtg gtgtttcaag tcttccgaat
     1921 agctcaaaag cttgtttaaa atctctttat tggttaagtg catacgaaaa gtaggacgat
     1981 aaaatcgctt atcactcagt ttacggctat cctgttgaat gagtttccag tagcgcttaa
     2041 tagccttgta ttcatgggat tttcgatgaa actgattcat gatttggaca cgcacacgac
     2101 tcatagcacg gctaagatgt tgtacaatgt gaaagcgttc aagaacgatt ttagcattcg
     2161 ggagtgaaac agtctgggag actgtttcag cctgagccta gaaatttgaa agcgaagctg
     2221 tttagccaag tcatagtaaa ggctaaacat atccatagta atgattttga cgcgacatcg
     2281 gacagctcta tcgtagcgaa gaaagtgatt tcggatgaca gcttgtgttc tgcctttaag
     2341 aatagtgata atattaagat tatcaaaatc ttgcgcaatg aagctcatct ttccctttgt
     2401 aaaagcatac tcatcccaag acataatctc aggaagacaa gaaaaatcat gtttaaagtg
     2461 aaaatcattg agcttacgaa taacagttga agttgagatg gaaagctgat gggcaatatc
     2521 agtcatagaa atcttttcaa ttaacttttg agcaatcttt tggttgatga tacgagggat
     2581 ttggtgattt ttctttacca ggggagtctc agcaaccatc atttttgaac agtgatagca
     2641 cttgaaacgg cgttttctaa ggagaattct agtaggcata ccagtcgttt caagataagg
     2701 aattttagaa ggtctttgaa agtcatattt cttcaattgg tttccgcact cagggcaaga
     2761 tggggcgtcg tagtccagtt tggcgatgat ttccttgtgt gtatccttat tgatgatgtc
     2821 taaaatctgg atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc
     2881 catatgaatc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
     2941 ttttctacac aaaataggct ccataatatc tatagggggg ttacccacta caaatattat
     3001 agagcccttt ttttgatgta cgacgggcat gtcgtatatc tgaggtgtaa gtcctcagtg
     3061 ggcacctgct accggtgaac ccaatagcga ttcccaagtc tgacgcagga aataagaatc
     3121 gtcagaggaa gggatagcga aatcgtggct ctacgaacag gaacgtgata ataaggccta
     3181 tatagcggat aaggtatctg gctggggcga ccactatcaa ttagtagctc agaagtcggt
     3241 acttaaacgt gctatatcaa aaccagtcct tgaaaaacgt gaactggttt cgtgtttgga
     3301 ttattacctt gaacgacatg cgttaaaagt tagttgaact gccgtatgcc gaacggcacg
     3361 tacggtggtg tgagaggggc tagagattat cccctactcg atttcgaaat ctagtggaat
     3421 gaatctggaa tagtccatcg agctttctaa tactctt
//
LOCUS       DBEJZJ010000070         2952 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000070 DBEJZJ010000000
VERSION     DBEJZJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.70"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(249..617)
                     /locus_tag="ACL3R8_001968"
                     /pseudo
     CDS             complement(249..617)
                     /locus_tag="ACL3R8_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            838..1815
                     /locus_tag="ACL3R8_001969"
     CDS             838..1815
                     /locus_tag="ACL3R8_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HGR1314771.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFARMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1812..2894
                     /locus_tag="ACL3R8_001970"
     CDS             1812..2894
                     /locus_tag="ACL3R8_001970"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR1314772.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT          912 a          637 c          533 g          870 t
ORIGIN      
        1 cttttattca tatttatatc ataacaaatt tgagcaataa tttcaatgat acaatttggc
       61 aatccacaat tcctctagca agccaaagca tcttacatca actccaacat ccgtatctgt
      121 agagattatg tagttttcta tctatggaat ttctagtaga ttgaagctag aatagtagac
      181 ctatacttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgtcctgttc
      241 tcatttcatt tcactataaa actatgaaaa gctaggtcat ctgagaagta attactatcg
      301 acaattgcga tagcgtatac tagtgcgatt tgtttgtagc tctggtgggt atcaccttca
      361 cgttggcgaa ttttttctag gttttgatta acctgactgc acagataagc ccataggcga
      421 ttgatgaaaa aattctgatg atgaacctga atttcgatga taacttggat tccattatct
      481 aactccgcca agacgtctat actagtatag aaatcttgcg ctgagtaggg catggaaggc
      541 aagacgtgaa tgttacttcc ctccaaaatc gtcacatttt ttgctggcaa gtccagcata
      601 tcgcggataa attgacaaat cattagttgg gctgatacct ggatgtctga gaatcctcct
      661 tttcctcctt ctattatagc acatttttaa atctaggttt gctagattct atgcttctat
      721 ctatttattc ggaaaagaaa gctaatagct tatttgaaat tttctcctct ctgttggata
      781 gtcccgtcta tctatgttat aatgaaagaa ggatttaaaa tcggaaaagg agtatttatg
      841 ctaaaattag gtgtcatcgg aactggcgct atcagccatc atttcataga agcagcccat
      901 accagtggag aataccaact ggtcgcaatc tattctagaa aactagaaac tgcagcaacc
      961 tttgcttctc gctatcagaa tatccaacta ttcgatcaat tagaagtctt cttcaaatct
     1021 tcttttgatt tagtctatat cgccagtcca aactccttac attttgctca ggcaaaagct
     1081 gccttgtctg ctggtaaaca tgttattctt gaaaagccag ctgtcactca accacaagaa
     1141 tggtttgatt tgattcaaac agctgaaaaa aataactgtt ttatctttga agcagctcgt
     1201 aattatcacg agaaagcctt tactactatc aaaaactttt tagcagataa gcaagtgtta
     1261 ggagcagatt tcaactatgc caaatactct tccaagatgc ctgacttatt ggctggacaa
     1321 acaccaaatg tcttttcaga ccgttttgct ggtggagccc tcatggattt ggggatttat
     1381 cccctctatg ctgctgttcg tctttttgaa aaagctaatg acgcgactta ccatgctcaa
     1441 cagcttgaca atagcattga cctaaatgga gatggtatcc tcttctaccc agactatcaa
     1501 gttcacatca aggctggaaa aaacatcact tccaatcttc cttgcgagat ttatacaaca
     1561 gatggaacct tgactctcaa cacgattgag catattcgct cagctatttt taccgaccac
     1621 caaggaaatc aagtccagct tcctatccaa caggctcctc atacgatgac tgaggaagtc
     1681 gctgcatttg cacgcatgat ccagcaacca gatctgaatc tctaccaaac ttggctgtat
     1741 gatgcaggct ctgttcatga gctactatat accatgcgcc agactgctgg cgttagattt
     1801 gaggcagaaa aatgaaaacc aaactaccga ctgaatggca agaactgagt gaccaactcg
     1861 gtttccaaga attcaccccc attcaaactc aactatttga gctccttctt gctggagaaa
     1921 acctcctagg agtgagccaa accggaactg gtaagaccct agcgtatctc ctaccaagtc
     1981 ttctcagact acaaaagaaa aaagcccaac aactcttgat tctagcacca aacacggaac
     2041 ttgctggaca gatttttgat gtatgtaaaa cgtgggcaga agctatcgga ttgactgctc
     2101 aactcttcct ttcaggttca agtcagaaac gacaaattga acgtcttaaa aaggggccag
     2161 aaattctgat tggaactcct ggccgtatct ttgaactcat taaacttaaa aaaatcaaga
     2221 tgatgaatgt ggaaaccatc atcctggatg aatttgacca attactagat gattctcaga
     2281 ttcactttgt agagaaaatc actcactacg cacctcgtga ccaccaactg gtctacatga
     2341 gtgccacgac caagtttgac caagaaaaga ttgtgccgaa tacacgcact attgatctct
     2401 ctgatcaaaa attggacaat atccagcatt tctacatgca ggtagaccaa cgtcatcgag
     2461 tggatatgct acgaaaactg gctcatgtag aggatttccg tggtctagtc ttcttcaata
     2521 gcctgtcaga ccttgggaat gccgaggaaa aactacagta tcgtgatata ttggctgttt
     2581 ccctcgctag tgatgttaat gttaaattta gaaaaatcat cttagaaaag tttaaagata
     2641 accaactaac cctgcttctt gcaactgacc ttttggctcg tggaattgat atcgatagcc
     2701 tagaatgtgt cgtaaacttt gatattccta gagatagcga aacctacaca caccgtgctg
     2761 gccgtactgg tcgtatgggc aaggaaggtt atgttatcac tctcgtcact catccagaag
     2821 aaatcaaaaa acttaaaaag tttgcaagta tccgagaaat tgtcctaaaa aaccaagaac
     2881 tctatatcaa ataaagcccc attgctctat acacatccag tgtatggagc ttttttataa
     2941 gcaattcaat tt
//
LOCUS       DBEJZJ010000071         2874 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000071 DBEJZJ010000000
VERSION     DBEJZJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.71"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..2702
                     /locus_tag="ACL3R8_001971"
     rRNA            <1..2702
                     /locus_tag="ACL3R8_001971"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2779..>2874
                     /gene="rrf"
                     /locus_tag="ACL3R8_001972"
     rRNA            2779..>2874
                     /gene="rrf"
                     /locus_tag="ACL3R8_001972"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          817 a          579 c          843 g          635 t
ORIGIN      
        1 gtagctgcag gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga
       61 agggcaaacc gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt
      121 atagaagaat gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt
      181 ctttgtactt agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg
      241 aggaccatct cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg
      301 gaaaggtgaa aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa
      361 caagttcgag cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac
      421 gttatgatgc gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg
      481 cgccttagta tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
      541 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
      601 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
      661 agggctagcg tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca
      721 tcccggatta ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga
      781 ctgcgagtgc taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc
      841 aaaataattg ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta
      901 gaagcagcta ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga
      961 aaatgtaccg gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg
     1021 agagcgttct atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag
     1081 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt
     1141 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta
     1201 tccgatggac aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt
     1261 aggctaacta aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc
     1321 aaatgcttaa ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag
     1381 tgacgtcaca ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa
     1441 ccgacacagg tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac
     1501 tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg acttaaagtc agccgcagtg
     1561 aataggccca agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt
     1621 atagggggtg acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag
     1681 gtatgaattg aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa
     1741 ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa
     1801 cgagagactc ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga
     1861 aagaccccat ggagctttac tgcagtttga tattgagtgt ctgtaccaca tgtacaggat
     1921 aggtaggagt ctaagagatc gggacgccag tttcgaagga gacgctgttg ggatactacc
     1981 cttgtgttat ggccactcta acccagatag gtgatcccta tcggagacag tgtctgacgg
     2041 gcagtttgac tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca
     2101 gaatggttgg aaatcattcg cagagtgtaa aggtataagg gagcttgact gcgagagcta
     2161 caactcgagc agggacgaaa gtcgggctta gtgatccggt ggttccgtat ggaagggcca
     2221 tcgctcaacg gataaaagct accctgggga taacaggctt atctccccca agagttcaca
     2281 tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct gtagtcggtc
     2341 ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag aacgtcgtga
     2401 gacagttcgg tccctatccg tcgcgggcgt aggaaatttg agaggatctg ctcctagtac
     2461 gagaggacca gagtggactt accgctggtg taccagttgt cttgccaaag gcatcgctgg
     2521 gtagctatgt agggaaggga taaacgctga aagcatctaa gtgtgaaacc cacctcaaga
     2581 tgagatttcc catgattata tatcagtaag agccctgaga gatgatcagg tagataggtt
     2641 agaagtggaa gtgtggcgac acatgtagcg gactaatact aatagctcga ggacttatcc
     2701 aaagtaactg agaatatgaa agcgaacggt tttcttaaat tgaatagata ttcaattttg
     2761 agtaggtatt actcagagtt aagtgacgat agcctaggag atacacctgt acccatgccg
     2821 aacacagaag ttaagcccta gaacgccgga agtagttggg ggttgccccc tgtg
//
LOCUS       DBEJZJ010000072         2809 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000072 DBEJZJ010000000
VERSION     DBEJZJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.72"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            62..1240
                     /locus_tag="ACL3R8_001973"
     CDS             62..1240
                     /locus_tag="ACL3R8_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314773.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
     gene            1449..>2809
                     /locus_tag="ACL3R8_001974"
     CDS             1449..>2809
                     /locus_tag="ACL3R8_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR1314774.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAV"
BASE COUNT         1007 a          492 c          574 g          736 t
ORIGIN      
        1 gactgcggct agctttctag tttgctcttt gatttttatt gagtattaga aaggagacct
       61 catgacactt ccagttagaa aatccctgca cgatgcagtt ttacaggctt cgaaagcgga
      121 tacttgggaa caagctacca aggaatggaa tgaagtttcc ttgatgttta acggtatcgg
      181 ccgtagcaat tgtgtctgtg gaaatgccat caaatacgct tatgaactct ttaacggtgt
      241 cacaggccaa cgcctctttc caattggtag cgactgtgtt cgtcattttc atcgattgtc
      301 ccttgaccag caattggaag aggaagaaaa actgctcaga aaggttgaaa atctaaccag
      361 aaaagctcag aaaaaggaaa aaatcaaggt caataaaagt gactttgacg agcgacttct
      421 aaaatggctc tgggaaaaag gtgttttcaa acccaatcgt ggcaatcaat ttgcgcctga
      481 gagagactac cagcttttcc tagaagtctt tcagggagga agttggacca aggcggaacc
      541 aaagaaaaag gctcggatgg aagaagtcct tgaaaagtgt atcaaaccat ttttacttgg
      601 gaaatcggat gaccaactct accttgtcaa gctaggcaag gagaaaattg actacgaaca
      661 agaactccgt atccaggcag agaaagaacg caagaagagg gataaaatcg ccaagcaata
      721 tgcagataat ctggttctag ccatgggacc cgcagagcgt gcttatcaag attactttgg
      781 ctttacagag accctgactc aagaagaacg caagtgggaa aaaattcttt ttggtaaaaa
      841 tagagcagaa cgggctatca aggccaaaca ataccaaaaa gagctggaaa aagaccaacg
      901 aattgccagt caggatccaa ttgaaagaaa acagaagcag acttggctcc tcaattccta
      961 ttttcgagag cttcctgaag aaaaagctcg attttctagg ctcttattag aatatcgaaa
     1021 aagtggtgaa gtaccctttt caactgaata cctgtcagat catctcatcg actttttcta
     1081 taaaatgaaa gcctttgaat ttgaaatcgc accagaacaa gtccgagatt ttctaaaaaa
     1141 aagcctgcag gaagaccatc gctcatcagc acaaggaagc tggatagaag gaattctcct
     1201 caactgcctc aaaccatttt taggacgatt agtgatatga gtaacaccta ccgtgtaaat
     1261 ttcatggtag gtgttattgt accccaaaat aatataaaac aaagtatgaa agcgcatctc
     1321 aattttaaga cttttttgta aattaagagt ataattaagg tatactgcct tttctataga
     1381 taatagataa tacactaata taataaaggt ctttgtaaca tatataaatt ttatttcaag
     1441 gaggaataat ggaaaagtat tttggtgaaa aacaagagcg tttttcattt agaaaattat
     1501 cagtaggact tgtatctgca acgatttcaa gtttattttt tatgtctgta ttagctagtt
     1561 catctgtgga tgctcaagaa actgcgggag ttcactataa atatgtggca gattcagagc
     1621 tatcatcaga agaaaagaag cagcttgtct atgatattcc gacatacgtg gagaatgatg
     1681 atgaaactta ttatcttgtt tataagttaa attctcaaaa tcaactggcg gaattaccaa
     1741 atactggaag caagaatgag aggcaagccc tagttgctgg tgctagctta gctgctctgg
     1801 gaattttaat ttttgctgtt tccaagaaaa aggttaagaa taaaacggta ttacatttag
     1861 tattggttgc gggaatagga aatggtgtct tagtttcagt ccatgcttta gaaaatcatc
     1921 ttttgctaaa ttacaatacg gactatgaat tgacctctgg agaaaaatta cctcttccta
     1981 aagagatttc aggttacact tatattggat atatcaaaga gggaaaaacg acttctgatt
     2041 ttgaagtaag taatcaagaa aaatcagcag ccactcctac aaaacaacaa aaggtggatt
     2101 ataatgttac accaaatttt gtagaccatc catcaacagt acaagctatt caggaacaaa
     2161 cacctgtttc ttcaactaag ccgacagaag ttcaagtagt tgaaaaacct ttctctactg
     2221 aattaatcaa tccaagaaaa gaagagaaac aatcttcaga ttctcaagaa caattagccg
     2281 aacataagaa tctagaaacg aagaaagagg agaagatttc tccaaaagaa aagactgggg
     2341 taaatacatt aaatccacag gatgaagttt tatcaggtca attgaacaaa cctgaactct
     2401 tatatcgtga ggaaactata gagacaaaaa tagattttca agaagaaatt caagaaaatc
     2461 ctgatttagc tgaaggaact gtaagagtaa aacaagaagg taaattaggt aagaaagttg
     2521 aaatcgtcag aatattctct gtaaacaagg aagaagtttc gcgagaaatt gtttcgactt
     2581 caacgactgc gcctattcca agaatagtcg aaaaaggtac taaaaaaact caagttataa
     2641 aggaacaacc tgagactggt gtagaacata aggacgtaca gtctggagct attgttgaac
     2701 ccgcaattca gcctgagttg ccagaagctg tagtaagtga taaaggcgta ccagaagttc
     2761 aaccagcgtt accggaagca gtcgtaaccg acaaaggtga gcccgctgt
//
LOCUS       DBEJZJ010000073         2602 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000073 DBEJZJ010000000
VERSION     DBEJZJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.73"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            51..518
                     /locus_tag="ACL3R8_001975"
     CDS             51..518
                     /locus_tag="ACL3R8_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314775.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLEKKIKRLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            528..734
                     /locus_tag="ACL3R8_001976"
     CDS             528..734
                     /locus_tag="ACL3R8_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR1314776.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            734..931
                     /locus_tag="ACL3R8_001977"
     CDS             734..931
                     /locus_tag="ACL3R8_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314777.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            934..1668
                     /locus_tag="ACL3R8_001978"
     CDS             934..1668
                     /locus_tag="ACL3R8_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR1314778.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1680..2321
                     /locus_tag="ACL3R8_001979"
     CDS             1680..2321
                     /locus_tag="ACL3R8_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR1314779.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2339..2569
                     /locus_tag="ACL3R8_001980"
     CDS             2339..2569
                     /locus_tag="ACL3R8_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314780.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          762 a          427 c          535 g          878 t
ORIGIN      
        1 tacggcaagg tgaagctgac gtggtttgaa gagattttag aagagtatta atgatagata
       61 aagtggtcag gaacctactc ctgacctttt tcttttgcaa aatgacaaaa atcataaact
      121 ttttgacaac tataattgtc aaaaagaaaa agatatgtta caatgaattc aagttaagaa
      181 ataggaagca gaaaggagtt ataatgtggg tactaggatt tatactattt atgattttct
      241 tttattctaa taattctaaa aaaatcaaga aactagagaa gaaaatcaaa agacttgagc
      301 gaaaagagaa aggaaacgca gaaatgtcga gattattaca agaaatgatt ggaaaggaac
      361 caattataac gggagtgtat attgggccag ataactggga agttgtggat gttgatgagg
      421 aatgggtaaa gctacgacgt gtagataata cgggaaaaga aaaattcaag ttgcaacgta
      481 ttgaggatat ccaaaccgtt gaatttgacg gagagtaggt gtgtaacatg caactaaaaa
      541 atcgtctaaa agagcttcga gctcgcgatg gtctcaatca aaccgaccta gccaaactgg
      601 caggggtttc cagacagacc attagcctac tagaacggga tgagtacacc ccatccatta
      661 tcattgccct gaaaatatct caaattttca acgaaacagt cgaatcggta tttcgtttgg
      721 aggaggacga gtgatgaaca agtataaagt gatttattat gtagtggtca tagctttatt
      781 agtcagcgta tttctactga ttgggatgga cctaagctgg tttaatccct atcaaagcga
      841 ccaatttgtt tgggtctact ttgctctcat cccagtaatt gaatggattg aaaagaaatc
      901 caaaaatcta gcaagtgaaa aaggagaatg aatatgaaaa agaaacgtag attgttattt
      961 ttgatgtcta ttgtcttggg ggggttcttg ggcatgtttg tagggatgtt taaggcacgt
     1021 gtcgaatccc acgaaattat tttagatgta aaagccttga tgccatggat atcagctatt
     1081 tgtttactga taggtttcat tagtatgttt ttgactttca atttcttaaa gaaaagcaga
     1141 aaatttcatt ccttgtatca agaggaaatg gatgacgatc tgaatgaaac ctattatgtg
     1201 caaatgtatc ggaatcttga gtttggaacc attgctttta atattacagg tgtagcgatt
     1261 ccattggcta tttttatttc attaagtgag gtgattatat tgcatacaaa ccctcaaaca
     1321 tttttccttt ctttcttact ctttgtggta ttcttagtcg ctcaaaaatc tctttttaaa
     1381 accattgcga ttgttcgtca gtttgatttg gaatttttcg ctacaccaaa ggatgtcttg
     1441 aactatataa attcttatga tgaaggggag cgtcaggcta atttggaaca gagttttcga
     1501 attttattcc aattacacca atatgtctta ccagccttat atatttttct tattatcatt
     1561 tctttcttga caggagagat tcagttacta gctttcttgc ttgtaggagc catccatgtt
     1621 tatatcaatg tgatgcagtt acctatggta aaacgttatt tcaaataaag gagttatcta
     1681 tgaaactact taaaaacctt ggctggtttc ttctagccct tctatccttt ttctttatct
     1741 atggctttat tcaggggctc gcgactgcgt cgcttgcttt aggcgcttca ccctatgctg
     1801 ttactctact ctatgtggtc ttggctggag tatatgtgta cggcatttac aaatggtatc
     1861 agaaagctcc tgtttatatt gagaagagcg gctttaaccg atttatttgg cttcctgcct
     1921 tggtttggtt cttatctctg gtcgttcaat tcttcttgcc agatgatcct tcagtaaatc
     1981 aacaaatagc gacagacttg accttgtctc aaccactttt ctcattcttt gctgtggtta
     2041 tttttgctcc tttgacggaa gagattgttt ttagagggat gttagcacgc tatctctttc
     2101 ctaagcagga caatagtaaa cgaaccctga tttttcttct ggtatctagt cttctatttg
     2161 ccttgattca ttttccaggt gatgtgcaac aattttttgt ctattttagc cttggtttta
     2221 gtttgggttt ggcttacatt agcagaaaag gtctggtcta cagtatttct cttcacgctt
     2281 tgaataattt agtcggcttt ttgatgattc tcatgctata atagagtcag gaggtcacat
     2341 gaaacgagta attttattag cagtgattca ggcagtcgtt ctatttttca tcattggagc
     2401 gctagcttat gccttcaaag gcgatttctt ctataactat ctagcagttg tctttgctcc
     2461 tattgcaggt gtactgcgtt ttgggacggc ttacataacg gaaattgtct tgcctcgaaa
     2521 ggcagccgaa atcgctgaaa agcgtaaagc aggcaaaaat tcaaaataaa agagtccggt
     2581 gaagttcatc ggatttttgt at
//
LOCUS       DBEJZJ010000074         2355 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000074 DBEJZJ010000000
VERSION     DBEJZJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.74"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..96
                     /locus_tag="ACL3R8_001981"
                     /pseudo
     CDS             1..96
                     /locus_tag="ACL3R8_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(68..1543)
                     /locus_tag="ACL3R8_001982"
     CDS             complement(68..1543)
                     /locus_tag="ACL3R8_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR1314781.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2278..2355
                     /locus_tag="ACL3R8_001983"
                     /pseudo
     CDS             2278..2355
                     /locus_tag="ACL3R8_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          701 a          522 c          431 g          701 t
ORIGIN      
        1 gctttttgcc atgctctaaa atcatcgcca aatcatcaaa ttgaaataag aaatagttta
       61 gataaaacta ttgacttttc ttatagtttg tctttctctt aatgacgttg atgtgattga
      121 cctctggatc ttccgtccct tggagggagc aaccacgttc cttggcaaat tggatatagt
      181 cgacaatttc tcgtgtgatg cgttcgccag gagccaagat agggattcct ggagggtaac
      241 acatgacaaa ttccccacag acctgtccaa cagattcgtc caaggtcaaa ctttttctct
      301 ctgaatagaa ggcttcttgc ggagacagca ctaactcggg ctgaatatat tctcctgcta
      361 tcaaatcttt tccatctctt gaatagagtc tcttaatatc agccagagca ccaaccaagc
      421 gctcgatgtc ttggatgcgg tcgccgatgg aaatataggc caagatattg ccgatatcac
      481 caaactcgat ctgaatgtcg tattcgtctc gcaagaggtc ataaacctcg atacctgtta
      541 agcctattcc ctgagtgtaa actgacaact tggttacatc aaaatcacag accgacacac
      601 catctattaa ctcttttgag taagcatagt aaccgccaat ggtattgatt tcatgacgag
      661 cgtactcgga tagctcaatg acttcctcaa acgactcttt accacgaagg gccaagttgc
      721 gacgtgaaat atccaaacta gccatcaata agtaagaggc agatgtagac tgggtcaggt
      781 ttataatctg acgaacgtac tcgggattca tctgctcccc gattaaaaga agcgaacttt
      841 gtgtcaaact cccaccagac ttatgcatgg aaactgctgc catatcagct cctgcatcca
      901 tagcagaaat tggaagttta ccagtgaaat gcaaatgcgc tccatgggct tcatctacta
      961 aaaccatcat gccagcttca tgagccattt ctgtcaaccc ctttaggtct gaacagatgc
     1021 cgtagtaagt aggattgttg attaggatag ccttagcatc tggatggtcc tttatggcct
     1081 gtgctactcg gtcattttca agacctaaag cgataccaat cttaggatct acactcatct
     1141 cgatatagat gggaatggca ccacatagaa ccaacgcatt gatagcagat ttatggacat
     1201 ttcgtggcag aataatctta tctcctgcct tgcaggttgc cagaatcata gtctgcaccg
     1261 atgaagttgt tccaccaatc attagaaagg catggctagc tccaaaagca tctgcagcca
     1321 gctcctctgc atcacgaata atcgaaatag gatggcctaa attatccaag ggtttcatcg
     1381 aattgacatc aatgcctaca catttttctc ctaagagttc gacaagttct ggatttcccc
     1441 gtccacgctt gtgacctgga acatcaaagg gaacaatcct tttcttgcgt aacttcacca
     1501 aggcctcata aattggggct tggttttgat ctaactcttt caaaacatac tcctttcaat
     1561 atttttagga ccttatgaaa actaaggaac taaaggttga ctcatgaaaa aagagcaggt
     1621 tttcacctgc tctgcaatct tctgacgtgt ttattttggt ttctgttgag tatgtctgtt
     1681 cccgatgttt cctaactctc tagtagcaaa tattacgtac tttattgatc gtttcacaag
     1741 atgacgtgtg ctttcaccac actaaaaatt tatgaattag aacaagtgtc ctaacatcaa
     1801 cttataaaag taggctttta accctatcaa taatgtggct tttcaaccac gcttcggcat
     1861 tcaaccctgc ctgtccgtag gcatttttta ctcgggttta tatttgctag aaaacatcat
     1921 ctcattttct aagctttatt actatatcat gtttttaaga acttgtaaag tattttttga
     1981 taaaaaataa aaatatagta gattgaaact agaatagtac acctctgctt ctaaaacatt
     2041 gttagaaata gattttactg tcctgatcga tttgttctgt tcttgtttca ttttactata
     2101 tgttcgtaaa tgaaagttct ataatgaagt tagccaccca gccctcctaa aaattagatg
     2161 gttcaactag ccgatagctc ttgtaggcat aagaaaacac ctctgtgtta tacttgttgt
     2221 tcaaccacaa acacaagaaa ggcgcagaga tgcaagacca ttatactaca aaaggcgaac
     2281 aaagggaaat caaatagaga aattgcctct ctgcttggaa aagttcctca aactatccac
     2341 actgaaatca agcgt
//
LOCUS       DBEJZJ010000075         2215 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000075 DBEJZJ010000000
VERSION     DBEJZJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.75"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            265..1810
                     /locus_tag="ACL3R8_001984"
     rRNA            265..1810
                     /locus_tag="ACL3R8_001984"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1862..1934
                     /locus_tag="ACL3R8_001985"
     tRNA            1862..1934
                     /locus_tag="ACL3R8_001985"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1895..1897,aa:Ala,seq:tgc)
     gene            2059..>2215
                     /locus_tag="ACL3R8_001986"
     rRNA            2059..>2215
                     /locus_tag="ACL3R8_001986"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          622 a          455 c          643 g          495 t
ORIGIN      
        1 cccgtacgga ctatggtatg ttgcgtcagg accacttgat gaaaaaaagt ttaaaaaaac
       61 ttaaaaatct tcaaaaaagt gttgacaagt gaaagtggct gtgatatact aatatagttg
      121 tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg aacaagacga accaatgtgc
      181 agggcgctac aacataagtt gtagtactga acaatgaaaa aacaataaat ctgtcagtga
      241 cagaaatgag tgagaactca aacttttaat gagagtttga tcctggctca ggacgaacgc
      301 tggcggcgtg cctaatacat gcaagtagaa cgctgaagga gaagcttgct tctctggatg
      361 agttgcgaac gggtgagtaa cgcgtaggta acctgcctgg tagcggggga taactattgg
      421 aaacgatagc taataccgca taagagtgga tgttgcatga catttgctta aaaggtgcac
      481 ttgcatcact accagatgga cctgcgttgt attagctagt tggtggggta acggctcacc
      541 aaggcgacga tacatagccg acctgagagg gtgatcggcc acactgggac tgagacacgg
      601 cccagactcc tacgggaggc agcagtaggg aatcttcggc aatggacgga agtctgaccg
      661 agcaacgccg cgtgagtgaa gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa
      721 cgagtgtgag agtggaaagt tcacactgtg acggtatctt accagaaagg gacggctaac
      781 tacgtgccag cagccgcggt aatacgtagg tcccgagcgt tgtccggatt tattgggcgt
      841 aaagcgagcg caggcggtta gataagtctg aagttaaagg ctgtggctta accatagtag
      901 gctttggaaa ctgtttaact tgagtgcaag aggggagagt ggaattccat gtgtagcggt
      961 gaaatgcgta gatatatgga ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg
     1021 acgctgaggc tcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgctg
     1081 taaacgatga gtgctaggtg ttagaccctt tccggggttt agtgccgtag ctaacgcatt
     1141 aagcactccg cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc
     1201 cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg cgaagaacct taccaggtct
     1261 tgacatccct ctgaccgctc tagagataga gttttccttc gggacagagg tgacaggtgg
     1321 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa
     1381 cccctattgt tagttgccat catttagttg ggcactctag cgagactgcc ggtaataaac
     1441 cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg ctacacacgt
     1501 gctacaatgg ctggtacaac gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc
     1561 agtctcagtt cggattgtag gctgcaactc gcctacatga agtcggaatc gctagtaatc
     1621 gcggatcagc acgccgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc
     1681 acgagagttt gtaacacccg aagtcggtga ggtaaccgta aggagccagc cgcctaaggt
     1741 gggatagatg attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat
     1801 cacctccttt ctaaggataa ggaactgcgc attggtcttg tttagtcttg agaggtcttg
     1861 tggggcctta gctcagctgg gagagcgcct gctttgcacg caggaggtca gcggttcgat
     1921 cccgctaggc tccattggtg agagatcacc aagtaatgca cattgaaaat tgaatatcta
     1981 tatcaaatag taacaagaaa ataaaccgaa aacgctgtag tattaataag agtttatgac
     2041 tgaaaggtca gaaaataagg ttaagttaat aagggcgcac ggtggatgcc ttggcactag
     2101 gagccgacga aggacgtgac aaacgacgat atgccttggg tagctgtaag taagcgatga
     2161 tccagggatt tccgaatggg ggaacccaac aggtaatacc tgttacccac atctg
//
LOCUS       DBEJZJ010000076         2156 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000076 DBEJZJ010000000
VERSION     DBEJZJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.76"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(<1..286)
                     /locus_tag="ACL3R8_001987"
     CDS             complement(<1..286)
                     /locus_tag="ACL3R8_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR1314782.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTAYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAAVFCIHES"
     gene            complement(231..413)
                     /locus_tag="ACL3R8_001988"
     CDS             complement(231..413)
                     /locus_tag="ACL3R8_001988"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR1314783.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            748..>2156
                     /gene="pcpA"
                     /locus_tag="ACL3R8_001989"
     CDS             748..>2156
                     /gene="pcpA"
                     /locus_tag="ACL3R8_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR1314784.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKGTKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
BASE COUNT          774 a          305 c          350 g          727 t
ORIGIN      
        1 tgctttcgtg gatacaaaaa acagccgcaa tttcttcata agtgcggtat tctcgcacat
       61 attgaagagt ggccataaga aggtcttcta gacttaattt aggttttcgt ccaccttttg
      121 cgtgtttaag ttgataagct gtttttaata cagctaacat ctctttaaaa gtggtacgct
      181 gaacaccaac aagacgctta aatcgtgtat cagttaattg tttacttgct tcataatttc
      241 gcagggagtc tattgactct ttggtaggtg tcaatgtttt tttcatctat cccgagaatt
      301 attttcccgc catttgtatt tgcaaatgct gagtaggttt cccagaaaga ctctggaaga
      361 ttgtttttag cttttttgta ttctaaatca accccttcaa attttaagtc catatttttc
      421 ctttacatct gttttttgtg gttctggtat ttgttcaagt tgagtgataa tatagcgaat
      481 tgaatttcga gagtttttac tcagttaatt tcttttttaa cccactttaa tttctttttt
      541 aacacgtgtt aaaaaagaaa ttaaagtggg ttaatttttc ttgacttaaa atttaaaaat
      601 gatatactgt gtttatggag agatgacaat ttataaaatg tactactcta ttctactaga
      661 taatgattga ataaaacttt ttataacaac ggctagcaaa gttataattt tatatctatt
      721 agaaaataaa tatgtaagga aatttaaatg aaaaaaacta caatattatc attaactaca
      781 gctgcagtta ttttagcagc atatgtccct aatgaaccaa tcctagcaga tactcctagt
      841 tcggaagtaa tcaaagagac taaagttgga agtattattc aacaaaataa tatcaaatat
      901 aaggttctaa ctgtagaagg taacatagga actgttcaag tgggtaatgg agttactcct
      961 gtagagtttg aagctggtca agatggaaaa ccattcacga ttcctacaaa aatcacagta
     1021 ggtgataaag tatttaccgt tactgaagta gctagtcaag cttttagtta ttatccagat
     1081 gaaacaggta gaattgtcta ctatcctagc tctattacta tcccatcaag cataaaaaaa
     1141 atacaaaaaa aaggcttcca tggaagtaaa gctaaaacta ttatttttga caaaggtagt
     1201 cagctggaga aaattgaaga tagagctttt gatttttctg aattagaaga gattgaattg
     1261 cctgcatctc tagaatatat tggaacaagt gcattttctt ttagtcaaaa attgaaaaag
     1321 ctaacctttt cctcaagttc aaaattagaa ttaatatcac atgaggcttt tgctaattta
     1381 tcaaatttag agaaactaac attaccaaaa tcggttaaaa cattaggaag taatctattt
     1441 agactcacta ctagcttaaa acatgttgat gttgaagaag gaaatgaatc gtttgcctca
     1501 gttgatggtg ttttgttttc aaaagataaa acccaattaa tttattatcc aagtcaaaaa
     1561 aatgacgaaa gttataaaac gcctaagggg acaaaagaac ttgcatcata ttcgtttaat
     1621 aaaaattctt acttgaaaaa actcgaattg aatgaaggtt tagaaaaaat tggtactttt
     1681 gcatttgcag atgcgattaa acttgaagaa attagcttac caaatagttt agaaactatt
     1741 gaacgtttag ccttttacgg taatttagaa ttaaaagaac ttatattacc agataatgtt
     1801 aaaaattttg gtaaacacgt tatgaacggt ttaccaaaat taaaaagttt aacaattggt
     1861 aataatatca actcattgcc gtccttcttc ctaagtggcg tcttagattc attaaaggaa
     1921 attcatatta agaataaaag tacagagttt tctgtgaaaa aagatacatt tgcaattcct
     1981 gaaactgtta agttctatgt aacatcagaa catataaaag atgttcttaa atcaaattta
     2041 tctactagta atgatatcat tgttgaaaaa gtagataata taaaacaaga aactgatgta
     2101 gctaaaccta aaaagaattc taatcaggga gtagttggtt gggttaaaga caaagg
//
LOCUS       DBEJZJ010000077         1653 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000077 DBEJZJ010000000
VERSION     DBEJZJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.77"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            704..922
                     /locus_tag="ACL3R8_001990"
                     /pseudo
     CDS             704..922
                     /locus_tag="ACL3R8_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1222..1509)
                     /locus_tag="ACL3R8_001991"
                     /pseudo
     CDS             complement(1222..1509)
                     /locus_tag="ACL3R8_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1502..1653
                     /locus_tag="ACL3R8_001992"
                     /pseudo
     CDS             1502..1653
                     /locus_tag="ACL3R8_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT          569 a          251 c          303 g          530 t
ORIGIN      
        1 gaacagaatc ctctcttgat tgaagacaag ctagtcatta ggctggtttg tctttttgtc
       61 aactgtagtg ggttgatata atagtattag tgagtgggat aaaagtttca tttagtttat
      121 tcagtacaaa tttaacgggt caagatttat atactagtgg tgtttttggg gctgagagaa
      181 gtatcttgat tttatgtgtg gtttttatac ttacagttgt tctgctccaa agagcttgta
      241 gagaagaatt agctcataaa ggagattgat tattttgata tcaaaaaaat gcacaggata
      301 acctgatgca tttttttagc gacaatgctt gctacttcct tctgtcgaat ttagacaatt
      361 ttaaataaaa gaatgaaata ttccctactg tatttttaga cgaagaacgt tagttaataa
      421 tactcaaatt tatttcaaac tctttgatta gtatgaattt agctctacag aaaaataaaa
      481 aatgtgataa aaatttcaac tactcttatc tataataaag ctacctgttc tttgaaaatt
      541 gaatccactc cgtcttgatt agcgtgcctg tgtaagtagg gactgagagt atttccctgt
      601 gaagggcaac tggcacaaga cgtgtgtgag aattttctaa cagacacgga gtttatcgtt
      661 tccagactca aacgatgcga caaactagat aaaggagtta atcatgaagg tagtaaactt
      721 gtatgatttg aaacaaatgg gaaataaagg tggttgtacc atccaattga ttcatcactt
      781 tccttttggt atgggcttag gacatctcaa aaaagactac attgaattta aacgtgttgg
      841 tatctttgat gggaaagcag tagaagttac tcttcgagaa ccttattcga gagatctact
      901 tcaggttgtc aagtcaataa agtaactgac accatgagta taattattag aaacgtggaa
      961 tcttattaaa ttttataata aatatattaa atgaaaaatt attagatata aacttatgta
     1021 ataaaacatt gaggaaataa taaaaatcta tgggtaatgt tctgaaagta cttttaggtt
     1081 aggagagaaa tataatgatt tttgaaaatt gattcaaaaa atagcgaatt gtagaaaacg
     1141 cttaacaaat ggtgtataat agacttccag cgaaacaaaa tatgctacaa taaacctatg
     1201 aattataaag caaccttata ctcatctgtc ttcacaaagc attctagtcc atctccgatt
     1261 aacgatggac tttatcatct ccttctccag tccttgtatg acatcttcca aagttcgaaa
     1321 ggctttattc ttaaatccac gtttacgaat ctctttccac acttattcaa tggggttcat
     1381 ttctggtgtg tatggaggaa taaatgcaaa gccaatatta gtcggaatct ttaaggcact
     1441 tgatttatgc catatagcat tgtccataac gaataaaaga taatcatctg gataagcttg
     1501 tgaaagcttg gctgacagtg gttatcaagg gctcatgaag atatatcttc aagcacaaac
     1561 tccacgtaaa tccagcaaac tcaagccgct aacagctgaa gataaagcct ataaccatgc
     1621 gctatctaag gagagaagca aggttgagaa tat
//
LOCUS       DBEJZJ010000078         1475 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000078 DBEJZJ010000000
VERSION     DBEJZJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.78"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(1..647)
                     /locus_tag="ACL3R8_001993"
                     /pseudo
     CDS             complement(1..647)
                     /locus_tag="ACL3R8_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(735..1256)
                     /locus_tag="ACL3R8_001994"
                     /pseudo
     CDS             complement(735..1256)
                     /locus_tag="ACL3R8_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1276..1371)
                     /locus_tag="ACL3R8_001995"
                     /pseudo
     CDS             complement(1276..1371)
                     /locus_tag="ACL3R8_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          390 a          329 c          286 g          470 t
ORIGIN      
        1 ggtaaatagg cctctaaaac ctctttgttt acgagagttt cctcgtttgg aagacattct
       61 agaagatagg atagatattt ctcactattt agttgatgac gtttagctgt ttccaataag
      121 ctcataataa tagctcttgc tttagctcct tcaaaaactt tgagaaaaca accaccctcg
      181 cttttttaaa ctgagcttag gctaaaagag tccagtggac tcttttactc cgtcccataa
      241 ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt ccgtctttta
      301 aaatggtctt aaaggtttct tcatacttga ggctgtattc aattgccctt cctagttttg
      361 aacccgataa aactgactga cgacggcacc aagcaaagaa gtcttctatt aggggttgga
      421 gctcttcttg acgtttctgt agtcgttcat cagctggcaa agcctcccag tctctttcca
      481 aggaaaataa ctgatcacaa taggctaatc ctttagctcc taaagatgat ttatccgctt
      541 gcttgggggg cgcttcaaaa aacttccttc tcacatgtgc ccaacatcca acaagttcag
      601 cttctgccag ttgactgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      661 gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac taaagtccta
      721 agttactgcc gcaacatgtc acaatgcaca tagccagaat aatctcctag gaattcttgt
      781 actactaaac cactccgacg ctgatcatgg tggtacagcg tgattgcttg attttcagct
      841 ttcccagaca aaaaggtcca atagtaggtc agctgactat cactctctag caccctataa
      901 gaagtttcat ctgcatgaag taagggcttg agtcaatagt ctcgttataa aggggcttta
      961 ggaataggag ctttcacgat tttatcactc ggatttttat cactgcatgc ttggcatttg
     1021 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac caattcttgt
     1081 ccttgaagac tccctccaat ctcttttaga tctccctgac aatcagggca aatcctctct
     1141 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
     1201 ttagatttct tacgtttgta ggtaatttct tctgtttcaa ctgggaacat ctccatcttc
     1261 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
     1321 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgca gaagggcaag
     1381 ttcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
     1441 atgagcttcc ctctctgttt tctaacttta ttata
//
LOCUS       DBEJZJ010000079         1323 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000079 DBEJZJ010000000
VERSION     DBEJZJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.79"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            1..291
                     /locus_tag="ACL3R8_001996"
                     /pseudo
     CDS             1..291
                     /locus_tag="ACL3R8_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(1032..1292)
                     /locus_tag="ACL3R8_001997"
     CDS             complement(1032..1292)
                     /locus_tag="ACL3R8_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR1314785.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT          449 a          254 c          224 g          396 t
ORIGIN      
        1 atcaaaaaag tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg
       61 aagatatatc ctcaagcaca aactccacgt aaagccagca aactcaagcc gctaacagct
      121 gaagataaag cctataacca tgcgctatcc aaggagagaa gcaaggttga gaacatcttt
      181 gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc
      241 ggattacgaa tgaatttgat tgctggtatt atcaatcatg aactaggatt ttggtttcgc
      301 aggaagtcta ttatatatgc acagacatat gaaatctttt tgagacagca gttatgatat
      361 atttatccat tcacaacatc ttctgtacta atactacaat attggtacat tttgattaca
      421 caatcgtttc aaaaaatatg atggaagcct gagtatttta tagtaattcc cttcctatca
      481 actagatcaa ccagttgagt gttgaatgtt gaaacaccct agcctcagca aaggactatg
      541 atcagcattt cctagccaat aggacgctcc aaatcaccta ttctaagtcc atcactagct
      601 tggtcagtaa gatacagact gcaaggcgag actgacgtgg ttgatgagat tttggaagag
      661 tattacaatc atagattcac cagtagactt gaccgcagat ttaactatag tagattgaaa
      721 ctagaatagt acatctctgc ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
      781 aatttgtcct gttctcgttt catttcacta tactaaaaaa ccacctgaaa caaatcaagt
      841 gactagagga taaaaacaaa gactaggcaa aaagttttga aaagcaaaaa acgcataata
      901 tcaggtcttg aaaaaccttg atactatacg tttgattgtg ggaagattga cttcattttc
      961 tcctgaaatt gaagtttttt ctagtttcca gatatagacg aattcaatat agccatctcg
     1021 ctacaattat tttaaccatc gagaaaattt ttcagaattt caaaaatttc attttgatcc
     1081 aatgaaatgt catcattttg aagaatagtt gacttcacag gctctaattc tatcacaaag
     1141 cggtgtatgt ctgcttttac cgcactactt gatgttatag ccgataactt ttcatctcct
     1201 agcaaggaag ctgtcaaacg ggtaaggtca ttcaaatgct ttttaatgga cttacttaaa
     1261 ccttgagcac ctgtagcaga gcgttccctc atatccagcc aagctttagc cttaaaaata
     1321 att
//
LOCUS       DBEJZJ010000080          956 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000080 DBEJZJ010000000
VERSION     DBEJZJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.80"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            <1..>956
                     /gene="phtD"
                     /locus_tag="ACL3R8_001998"
     CDS             <1..>956
                     /gene="phtD"
                     /locus_tag="ACL3R8_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR1314786.1"
                     /translation="PAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETA
                     AGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEA
                     LDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKY
                     TTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPS
                     TGHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNI
                     KFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          308 a          187 c          215 g          246 t
ORIGIN      
        1 accagctcca agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg
       61 cgatggttat gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc
      121 agcagaaaca gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa
      181 gctaggagct aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta
      241 tgacttacta gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt
      301 tgaggctttg gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt
      361 agtggatgat attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc
      421 aaatgcgcaa attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta
      481 cacaacagaa gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc
      541 ctatgtaact ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc
      601 tgagagagcg gcagcccagg cttatgctaa agagaaaggt ttgacccctc cttcgacagg
      661 ccatcaggat tcaggaaata ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa
      721 agcagctaag aaggtgccac ttgatcgtat gccttacaat cttcaatata ctgtagaagt
      781 caaaaacggt agtttaatca tacctcatta tgaccattac cataacatca aatttgagtg
      841 gtttgacgaa ggcctttatg aggcacctaa ggggtatagt cttgaggatc ttttggcgac
      901 tgtcaagtac tatgtcgaac atccaaacga acgtccgcat tcagataatg gttttg
//
LOCUS       DBEJZJ010000081          745 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.81, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000081 DBEJZJ010000000
VERSION     DBEJZJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.81"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            151..684
                     /gene="queF"
                     /locus_tag="ACL3R8_001999"
     CDS             151..684
                     /gene="queF"
                     /locus_tag="ACL3R8_001999"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR1314787.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKPLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT          219 a          182 c          143 g          201 t
ORIGIN      
        1 gtcctgttct tatttcattt tactatataa gtagaatatt acgatgtttg ggatatgcca
       61 tcgctaaaaa aacctcgatt tggtattttt tagctcccta atgggagctt tttgcgtgct
      121 ctgaacattt cccattttgg aaggagtact atgaaacgtc aatcagcctt ggtcgtcttt
      181 agtggtggtc aagattcaac aacctgcctt ttctgggcca tgcaacacta tgaaacagtc
      241 gaagctgtca cctttgccta cggccaacgt catcacctcg aaattcaaat tgctagagaa
      301 atcgctaagg aacagggcat tcgtcaccat atcctcgata tgtctctgct gggacaaatc
      361 actgctcagc cagactttgc gacgattcat atttcctaca ttcctgacaa gctctgtgtc
      421 gagtcaaaac ccctcaaact atatctattt agctaccgaa accacggaga tttccacgaa
      481 aactgtatca acaccatcgg gaaagacttg gtcaacttgc tagaccctcg ctatttagaa
      541 gtctggggaa aattcactcc gcgcggtggc atttcaatcg acccctacta taactacggt
      601 aagcaaggaa ctaagtatga gggcttggca gaacaacgcc tcttccaaca cgacctttat
      661 ccagagaaaa ttgacaaccg ctaaactcat actcaatgaa aatcaaagag caaactagga
      721 agttagccgc aggttgctca aagca
//
LOCUS       DBEJZJ010000082          711 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.82, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000082 DBEJZJ010000000
VERSION     DBEJZJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.82"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            complement(296..607)
                     /locus_tag="ACL3R8_002000"
     CDS             complement(296..607)
                     /locus_tag="ACL3R8_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR1314788.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(622..>711)
                     /locus_tag="ACL3R8_002001"
     CDS             complement(622..>711)
                     /locus_tag="ACL3R8_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR1314789.1"
                     /translation="VQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          231 a          131 c          112 g          237 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact ctagacggat
       61 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag ttgaaaatta
      121 acccagtttt aacaagtagt caaaatacca gataaaggaa aaaagtcttt aaaatcttaa
      181 aaacgcatag tatcaggtat tgaacaatct tgatattatg cgttttattg tgggaagatt
      241 tacttcattt tctcttggaa ttgagttttc tcctacttca aaactagatg atttgctatt
      301 taaaatagcg ttccttatga ttttggcaac ctggattaaa gcgagaaaaa caaaaggggc
      361 aacttaaact ttctttatat tgcttatatg ttagtagttt tagacaaaca ccacataaaa
      421 taggcttatc ctgtatcaaa gataagggat acggctcaaa agggtgattt tctaatgaat
      481 catgacaccg ataacaagca taatactttt tacaatcata gcattgtaaa gcaataatat
      541 ccagcttgct atggtaatga atgcatcttg tttgcttatc cactaagaaa ccctgtgcct
      601 ctatcatttc cttttccttt cttaagctcg aactgtgacg ctggttccat cttccttata
      661 aaaattgatg agtccttctt ttaatgcacg aaccatgtct cctgattgaa c
//
LOCUS       DBEJZJ010000083          641 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.83, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000083 DBEJZJ010000000
VERSION     DBEJZJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.83"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            56..418
                     /locus_tag="ACL3R8_002002"
     CDS             56..418
                     /locus_tag="ACL3R8_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR1314790.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          212 a           81 c          120 g          228 t
ORIGIN      
        1 gcaacctgag gctagtttcc tagtctgctc tttggttttc attgagtata acacattgtt
       61 agaagttggt ttaaattccc taatcagttt gttcacattt accttcgata tattatatcc
      121 catagttaag gttggtcata cagatgatta tagtcatgga gccgtaaaac ttagtgtttc
      181 tttagttgac aaagatgcca tgaaaaaaat atctgtaact gtaataggat attttgaaat
      241 aaatatagat gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttatcc
      301 ttatttacgt tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct
      361 acctaccatt aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt
      421 tattagctca ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat
      481 tatacagcaa ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat
      541 gatttatctg tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat
      601 aatcagtaga agccttgcta ataatgagga ggttagttta t
//
LOCUS       DBEJZJ010000084          619 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 638195
            SAMN38240094-rid24860983.denovo.84, whole genome shotgun sequence.
ACCESSION   DBEJZJ010000084 DBEJZJ010000000
VERSION     DBEJZJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38240094
            Sequence Read Archive: SRR26818462
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002575659.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002575659.1
            Genome Coverage       :: 52x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 13:13:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,003
            CDSs (total)                      :: 1,967
            Genes (coding)                    :: 1,821
            CDSs (with protein)               :: 1,821
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 69 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 44 of 146
            Pseudo Genes (multiple problems)  :: 30 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38240094-rid24860983.denovo.84"
                     /strain="GPSC3"
                     /isolate="638195"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2018"
                     /collected_by="UKHSA"
     gene            82..561
                     /locus_tag="ACL3R8_002003"
     CDS             82..561
                     /locus_tag="ACL3R8_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR1314791.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          240 a           77 c          145 g          157 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tgtcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaat gaaaaaaatt agaaaaagta
      601 gttgacaaag tttgaaaag
//
